% alzhub.org library filter % Source: https://alzhub.org/research?category=genetics_genes&year=2012 % 38 entries, in the order the page lists them. Built from alzhub.org's own records. % 0 entries have no readable author in the source record and carry no author field. @article{lohmann2012-22503161, author = {Lohmann, Ebba and Guerreiro, Rita J and Erginel-Unaltuna, Nihan and Gurunlian, Nicole and Bilgic, Basar and Gurvit, Hakan and Hanagasi, Hasmet A and Luu, Nga and others}, title = {{Identification of PSEN1 and PSEN2 gene mutations and variants in Turkish dementia patients}}, journal = {Neurobiology of aging}, year = {2012}, doi = {10.1016/j.neurobiolaging.2012.02.020}, pmid = {22503161}, url = {https://doi.org/10.1016/j.neurobiolaging.2012.02.020} } @article{areagomez2012-22892566, author = {Area-Gomez, E. and Del Carmen Lara Castillo, M. and Tambini, M. D. and Guardia-Laguarta, C. and de Groof, A. J. and Madra, M. and Ikenouchi, J. and Umeda, M. and others}, title = {{Upregulated function of mitochondria-associated ER membranes in Alzheimer disease}}, journal = {The EMBO journal}, year = {2012}, doi = {10.1038/emboj.2012.202}, pmid = {22892566}, url = {https://doi.org/10.1038/emboj.2012.202} } @article{verret2012-22541439, author = {Verret, L. and Mann, E. O. and Hang, G. B. and Barth, A. M. and Cobos, I. and Ho, K. and Devidze, N. and Masliah, E. and others}, title = {{Inhibitory interneuron deficit links altered network activity and cognitive dysfunction in Alzheimer model}}, journal = {Cell}, year = {2012}, doi = {10.1016/j.cell.2012.02.046}, pmid = {22541439}, url = {https://doi.org/10.1016/j.cell.2012.02.046} } @article{chavezgutierrez2012-22505025, author = {Chávez-Gutiérrez, L. and Bammens, L. and Benilova, I. and Vandersteen, A. and Benurwar, M. and Borgers, M. and Lismont, S. and Zhou, L. and others}, title = {{The mechanism of γ-Secretase dysfunction in familial Alzheimer disease}}, journal = {The EMBO journal}, year = {2012}, doi = {10.1038/emboj.2012.79}, pmid = {22505025}, url = {https://doi.org/10.1038/emboj.2012.79} } @article{pera2013-23224319, author = {Pera, M. and Alcolea, D. and Sánchez-Valle, R. and Guardia-Laguarta, C. and Colom-Cadena, M. and Badiola, N. and Suárez-Calvet, M. and Lladó, A. and others}, title = {{Distinct patterns of APP processing in the CNS in autosomal-dominant and sporadic Alzheimer disease}}, journal = {Acta neuropathologica}, year = {2013}, doi = {10.1007/s00401-012-1062-9}, pmid = {23224319}, url = {https://doi.org/10.1007/s00401-012-1062-9} } @article{haass2012-22553493, author = {Haass, C. and Kaether, C. and Thinakaran, G. and Sisodia, S.}, title = {{Trafficking and proteolytic processing of APP}}, journal = {Cold Spring Harbor perspectives in medicine}, year = {2012}, doi = {10.1101/cshperspect.a006270}, pmid = {22553493}, url = {https://doi.org/10.1101/cshperspect.a006270} } @article{esparza2013-23225543, author = {Esparza, T. J. and Zhao, H. and Cirrito, JR. and Cairns, N. J. and Bateman, R. J. and Holtzman, D. M. and Brody, D. L.}, title = {{Amyloid-β oligomerization in Alzheimer dementia versus high-pathology controls}}, journal = {Annals of neurology}, year = {2013}, doi = {10.1002/ana.23748}, pmid = {23225543}, url = {https://doi.org/10.1002/ana.23748} } @article{pottier2012-22472873, author = {Pottier, C. and Hannequin, D. and Coutant, S. and Rovelet-Lecrux, A. and Wallon, D. and Rousseau, S. and Legallic, S. and Paquet, C. and others}, title = {{High frequency of potentially pathogenic SORL1 mutations in autosomal dominant early-onset Alzheimer disease}}, journal = {Molecular psychiatry}, year = {2012}, doi = {10.1038/mp.2012.15}, pmid = {22472873}, url = {https://doi.org/10.1038/mp.2012.15} } @article{ly2013-23202730, author = {Ly, P. T. and Wu, Y. and Zou, H. and Wang, R. and Zhou, W. and Kinoshita, A. and Zhang, M. and Yang, Y. and others}, title = {{Inhibition of GSK3β-mediated BACE1 expression reduces Alzheimer-associated phenotypes}}, journal = {The Journal of clinical investigation}, year = {2013}, doi = {10.1172/jci64516}, pmid = {23202730}, url = {https://doi.org/10.1172/jci64516} } @article{tweedie2012-22642825, author = {Tweedie, D. and Ferguson, R. A. and Fishman, K. and Frankola, K. A. and Van Praag, H. and Holloway, H. W. and Luo, W. and Li, Y. and others}, title = {{Tumor necrosis factor-α synthesis inhibitor 3,6'-dithiothalidomide attenuates markers of inflammation, Alzheimer pathology and behavioral deficits in animal models of neuroinflammation and Alzheimer's disease}}, journal = {Journal of neuroinflammation}, year = {2012}, doi = {10.1186/1742-2094-9-106}, pmid = {22642825}, url = {https://doi.org/10.1186/1742-2094-9-106} } @article{zhou2012-22692213, author = {Zhou, L. and Barão, S. and Laga, M. and Bockstael, K. and Borgers, M. and Gijsen, H. and Annaert, W. and Moechars, D. and others}, title = {{The neural cell adhesion molecules L1 and CHL1 are cleaved by BACE1 protease in vivo}}, journal = {The Journal of biological chemistry}, year = {2012}, doi = {10.1074/jbc.m112.377465}, pmid = {22692213}, url = {https://doi.org/10.1074/jbc.m112.377465} } @article{oules2012-22915123, author = {Oulès, B. and Del Prete, D. and Greco, B. and Zhang, X. and Lauritzen, I. and Sevalle, J. and Moreno, S. and Paterlini-Bréchot, P. and others}, title = {{Ryanodine receptor blockade reduces amyloid-β load and memory impairments in Tg2576 mouse model of Alzheimer disease}}, journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience}, year = {2012}, doi = {10.1523/jneurosci.0875-12.2012}, pmid = {22915123}, url = {https://doi.org/10.1523/jneurosci.0875-12.2012} } @article{vardarajan2012-22673115, author = {Vardarajan, B. N. and Bruesegem, S. Y. and Harbour, M. E. and Inzelberg, R. and Friedland, R. and St George-Hyslop, P. and Seaman, M. N. and Farrer, L. A.}, title = {{Identification of Alzheimer disease-associated variants in genes that regulate retromer function}}, journal = {Neurobiology of aging}, year = {2012}, doi = {10.1016/j.neurobiolaging.2012.04.020}, pmid = {22673115}, url = {https://doi.org/10.1016/j.neurobiolaging.2012.04.020} } @article{mori2012-22219198, author = {Mori, T. and Rezai-Zadeh, K. and Koyama, N. and Arendash, G. W. and Yamaguchi, H. and Kakuda, N. and Horikoshi-Sakuraba, Y. and Tan, J. and others}, title = {{Tannic acid is a natural β-secretase inhibitor that prevents cognitive impairment and mitigates Alzheimer-like pathology in transgenic mice}}, journal = {The Journal of biological chemistry}, year = {2012}, doi = {10.1074/jbc.m111.294025}, pmid = {22219198}, url = {https://doi.org/10.1074/jbc.m111.294025} } @article{avrahami2013-23155049, author = {Avrahami, L. and Farfara, D. and Shaham-Kol, M. and Vassar, R. and Frenkel, D. and Eldar-Finkelman, H.}, title = {{Inhibition of glycogen synthase kinase-3 ameliorates β-amyloid pathology and restores lysosomal acidification and mammalian target of rapamycin activity in the Alzheimer disease mouse model: in vivo and in vitro studies}}, journal = {The Journal of biological chemistry}, year = {2013}, doi = {10.1074/jbc.m112.409250}, pmid = {23155049}, url = {https://doi.org/10.1074/jbc.m112.409250} } @article{ho2012-22606286, author = {Ho, Y. S. and Yang, X. and Yeung, S. C. and Chiu, K. and Lau, C. F. and Tsang, A. W. and Mak, J. C. and Chang, R. C.}, title = {{Cigarette smoking accelerated brain aging and induced pre-Alzheimer-like neuropathology in rats}}, journal = {PloS one}, year = {2012}, doi = {10.1371/journal.pone.0036752}, pmid = {22606286}, url = {https://doi.org/10.1371/journal.pone.0036752} } @article{wallon2012-22475797, author = {Wallon, D. and Rousseau, S. and Rovelet-Lecrux, A. and Quillard-Muraine, M. and Guyant-Maréchal, L. and Martinaud, O. and Pariente, J. and Puel, M. and others}, title = {{The French series of autosomal dominant early onset Alzheimer's disease cases: mutation spectrum and cerebrospinal fluid biomarkers}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2012}, doi = {10.3233/jad-2012-120172}, pmid = {22475797}, url = {https://doi.org/10.3233/jad-2012-120172} } @article{krstic2013-23183882, author = {Krstic, D. and Knuesel, I.}, title = {{Deciphering the mechanism underlying late-onset Alzheimer disease}}, journal = {Nature reviews. Neurology}, year = {2013}, doi = {10.1038/nrneurol.2012.236}, pmid = {23183882}, url = {https://doi.org/10.1038/nrneurol.2012.236} } @article{muller2012-22355794, author = {Müller, U. C. and Zheng, H.}, title = {{Physiological functions of APP family proteins}}, journal = {Cold Spring Harbor perspectives in medicine}, year = {2012}, doi = {10.1101/cshperspect.a006288}, pmid = {22355794}, url = {https://doi.org/10.1101/cshperspect.a006288} } @article{hitt2012-22988240, author = {Hitt, B. and Riordan, S. M. and Kukreja, L. and Eimer, W. A. and Rajapaksha, T. W. and Vassar, R.}, title = {{β-Site amyloid precursor protein (APP)-cleaving enzyme 1 (BACE1)-deficient mice exhibit a close homolog of L1 (CHL1) loss-of-function phenotype involving axon guidance defects}}, journal = {The Journal of biological chemistry}, year = {2012}, doi = {10.1074/jbc.m112.415505}, pmid = {22988240}, url = {https://doi.org/10.1074/jbc.m112.415505} } @article{maesako2012-22563077, author = {Maesako, M. and Uemura, K. and Kubota, M. and Kuzuya, A. and Sasaki, K. and Hayashida, N. and Asada-Utsugi, M. and Watanabe, K. and others}, title = {{Exercise is more effective than diet control in preventing high fat diet-induced β-amyloid deposition and memory deficit in amyloid precursor protein transgenic mice}}, journal = {The Journal of biological chemistry}, year = {2012}, doi = {10.1074/jbc.m112.367011}, pmid = {22563077}, url = {https://doi.org/10.1074/jbc.m112.367011} } @article{bien2012-22879596, author = {Bien, J. and Jefferson, T. and Causević, M. and Jumpertz, T. and Munter, L. and Multhaup, G. and Weggen, S. and Becker-Pauly, C. and others}, title = {{The metalloprotease meprin β generates amino terminal-truncated amyloid β peptide species}}, journal = {The Journal of biological chemistry}, year = {2012}, doi = {10.1074/jbc.m112.395608}, pmid = {22879596}, url = {https://doi.org/10.1074/jbc.m112.395608} } @article{chami2012-22654105, author = {Chami, L. and Buggia-Prévot, V. and Duplan, E. and Del Prete, D. and Chami, M. and Peyron, J. F. and Checler, F.}, title = {{Nuclear factor-κB regulates βAPP and β- and γ-secretases differently at physiological and supraphysiological Aβ concentrations}}, journal = {The Journal of biological chemistry}, year = {2012}, doi = {10.1074/jbc.m111.333054}, pmid = {22654105}, url = {https://doi.org/10.1074/jbc.m111.333054} } @article{wang2012-23024364, author = {Wang, C. and Sun, B. and Zhou, Y. and Grubb, A. and Gan, L.}, title = {{Cathepsin B degrades amyloid-β in mice expressing wild-type human amyloid precursor protein}}, journal = {The Journal of biological chemistry}, year = {2012}, doi = {10.1074/jbc.m112.371641}, pmid = {23024364}, url = {https://doi.org/10.1074/jbc.m112.371641} } @article{haining2012-23035126, author = {Haining, E. J. and Yang, J. and Bailey, R. L. and Khan, K. and Collier, R. and Tsai, S. and Watson, S. P. and Frampton, J. and others}, title = {{The TspanC8 subgroup of tetraspanins interacts with A disintegrin and metalloprotease 10 (ADAM10) and regulates its maturation and cell surface expression}}, journal = {The Journal of biological chemistry}, year = {2012}, doi = {10.1074/jbc.m112.416503}, pmid = {23035126}, url = {https://doi.org/10.1074/jbc.m112.416503} } @article{leroy2012-23026200, author = {Leroy, K. and Ando, K. and Laporte, V. and Dedecker, R. and Suain, V. and Authelet, M. and Héraud, C. and Pierrot, N. and others}, title = {{Lack of tau proteins rescues neuronal cell death and decreases amyloidogenic processing of APP in APP/PS1 mice}}, journal = {The American journal of pathology}, year = {2012}, doi = {10.1016/j.ajpath.2012.08.012}, pmid = {23026200}, url = {https://doi.org/10.1016/j.ajpath.2012.08.012} } @article{winkler2012-22532566, author = {Winkler, E. and Kamp, F. and Scheuring, J. and Ebke, A. and Fukumori, A. and Steiner, H.}, title = {{Generation of Alzheimer disease-associated amyloid β42/43 peptide by γ-secretase can be inhibited directly by modulation of membrane thickness}}, journal = {The Journal of biological chemistry}, year = {2012}, doi = {10.1074/jbc.m112.356659}, pmid = {22532566}, url = {https://doi.org/10.1074/jbc.m112.356659} } @article{ringman2012-22232349, author = {Ringman, J. M. and Schulman, H. and Becker, C. and Jones, T. and Bai, Y. and Immermann, F. and Cole, G. and Sokolow, S. and others}, title = {{Proteomic changes in cerebrospinal fluid of presymptomatic and affected persons carrying familial Alzheimer disease mutations}}, journal = {Archives of neurology}, year = {2012}, doi = {10.1001/archneurol.2011.642}, pmid = {22232349}, url = {https://doi.org/10.1001/archneurol.2011.642} } @article{catricala2012-22985434, author = {Catricala, S. and Torti, M. and Ricevuti, G.}, title = {{Alzheimer disease and platelets: how's that relevant}}, journal = {Immunity \& ageing : I \& A}, year = {2012}, doi = {10.1186/1742-4933-9-20}, pmid = {22985434}, url = {https://doi.org/10.1186/1742-4933-9-20} } @article{jeppsson2012-23048024, author = {Jeppsson, F. and Eketjäll, S. and Janson, J. and Karlström, S. and Gustavsson, S. and Olsson, L. L. and Radesäter, A. C. and Ploeger, B. and others}, title = {{Discovery of AZD3839, a potent and selective BACE1 inhibitor clinical candidate for the treatment of Alzheimer disease}}, journal = {The Journal of biological chemistry}, year = {2012}, doi = {10.1074/jbc.m112.409110}, pmid = {23048024}, url = {https://doi.org/10.1074/jbc.m112.409110} } @article{fisette2012-22303960, author = {Fisette, J. F. and Montagna, D. R. and Mihailescu, M. R. and Wolfe, M. S.}, title = {{A G-rich element forms a G-quadruplex and regulates BACE1 mRNA alternative splicing}}, journal = {Journal of neurochemistry}, year = {2012}, doi = {10.1111/j.1471-4159.2012.07680.x}, pmid = {22303960}, url = {https://doi.org/10.1111/j.1471-4159.2012.07680.x} } @article{guo2013-23262393, author = {Guo, C. and Wang, P. and Zhong, M. L. and Wang, T. and Huang, X. S. and Li, J. Y. and Wang, Z. Y.}, title = {{Deferoxamine inhibits iron induced hippocampal tau phosphorylation in the Alzheimer transgenic mouse brain}}, journal = {Neurochemistry international}, year = {2013}, doi = {10.1016/j.neuint.2012.12.005}, pmid = {23262393}, url = {https://doi.org/10.1016/j.neuint.2012.12.005} } @article{fuso2012-22221883, author = {Fuso, A. and Nicolia, V. and Ricceri, L. and Cavallaro, R. A. and Isopi, E. and Mangia, F. and Fiorenza, M. T. and Scarpa, S.}, title = {{S-adenosylmethionine reduces the progress of the Alzheimer-like features induced by B-vitamin deficiency in mice}}, journal = {Neurobiology of aging}, year = {2012}, doi = {10.1016/j.neurobiolaging.2011.12.013}, pmid = {22221883}, url = {https://doi.org/10.1016/j.neurobiolaging.2011.12.013} } @article{tokutake2012-22910909, author = {Tokutake, T. and Kasuga, K. and Yajima, R. and Sekine, Y. and Tezuka, T. and Nishizawa, M. and Ikeuchi, T.}, title = {{Hyperphosphorylation of Tau induced by naturally secreted amyloid-β at nanomolar concentrations is modulated by insulin-dependent Akt-GSK3β signaling pathway}}, journal = {The Journal of biological chemistry}, year = {2012}, doi = {10.1074/jbc.m112.348300}, pmid = {22910909}, url = {https://doi.org/10.1074/jbc.m112.348300} } @article{jin2012-22448035, author = {Jin, Seok Min and Youle, Richard J.}, title = {{PINK1- and Parkin-mediated mitophagy at a glance}}, journal = {Journal of Cell Science}, year = {2012}, doi = {10.1242/jcs.093849}, pmid = {22448035}, url = {https://doi.org/10.1242/jcs.093849} } @article{schenk2012-22951439, author = {Schenk, D. and Basi, G. S. and Pangalos, M. N.}, title = {{Treatment strategies targeting amyloid β-protein}}, journal = {Cold Spring Harbor perspectives in medicine}, year = {2012}, doi = {10.1101/cshperspect.a006387}, pmid = {22951439}, url = {https://doi.org/10.1101/cshperspect.a006387} } @article{wu2012-22728850, author = {Wu, Liyong and Rosa-Neto, Pedro and Hsiung, Ging-Yuek R and Sadovnick, A Dessa and Masellis, Mario and Black, Sandra E and Jia, Jianping and Gauthier, Serge}, title = {{Early-onset familial Alzheimer's disease (EOFAD)}}, journal = {The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques}, year = {2012}, doi = {10.1017/s0317167100013949}, pmid = {22728850}, url = {https://doi.org/10.1017/s0317167100013949} } @article{sanchez2012-22869752, author = {Sanchez, P. E. and Zhu, L. and Verret, L. and Vossel, K. A. and Orr, A. G. and Cirrito, JR. and Devidze, N. and Ho, K. and others}, title = {{Levetiracetam suppresses neuronal network dysfunction and reverses synaptic and cognitive deficits in an Alzheimer's disease model}}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, year = {2012}, doi = {10.1073/pnas.1121081109}, pmid = {22869752}, url = {https://doi.org/10.1073/pnas.1121081109} }