% alzhub.org library filter
% Source: https://alzhub.org/research?category=genetics_genes&institution=I136199984
% 59 entries, in the order the page lists them. Built from alzhub.org's own records.
% 0 entries have no readable author in the source record and carry no author field.

@article{lambert2013-24162737,
  author  = {Lambert, Jean‐Charles and Ibrahim‐Verbaas, Carla A. and Harold, Denise H. and Naj, Adam Christian and Sims, Rebecca and Bellenguez, Céline and others},
  title   = {{Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease}},
  journal = {Nature Genetics},
  year    = {2013},
  doi     = {10.1038/ng.2802},
  pmid    = {24162737},
  url     = {https://doi.org/10.1038/ng.2802}
}

@article{schultz2024-39074479,
  author  = {Schultz, S. A. and Liu, L. and Schultz, A. P. and Fitzpatrick, C. D. and Levin, R. and Bellier, J. P. and Shirzadi, Z. and Joseph-Mathurin, N. and others},
  title   = {{γ-Secretase activity, clinical features, and biomarkers of autosomal dominant Alzheimer's disease: cross-sectional and longitudinal analysis of the Dominantly Inherited Alzheimer Network observational study (DIAN-OBS)}},
  journal = {The Lancet. Neurology},
  year    = {2024},
  doi     = {10.1016/s1474-4422(24)00236-9},
  pmid    = {39074479},
  url     = {https://doi.org/10.1016/s1474-4422(24)00236-9}
}

@article{chan2015-26414614,
  author  = {Chan, G. and White, C. C. and Winn, P. A. and Cimpean, M. and Replogle, J. M. and Glick, L. R. and Cuerdon, N. E. and Ryan, K. J. and others},
  title   = {{CD33 modulates TREM2: convergence of Alzheimer loci}},
  journal = {Nature neuroscience},
  year    = {2015},
  doi     = {10.1038/nn.4126},
  pmid    = {26414614},
  url     = {https://doi.org/10.1038/nn.4126}
}

@article{delafuentearrillaga2025-40882668,
  author  = {de la Fuente‐Arrillaga, Carmen and Carlos, Silvia and Toledo, Estefanía and Barbería-Latasa, María and Razquín, Cristina and Ruiz‐Canela, Miguel and Gea, Alfredo and Martínez‐González, Miguel Ángel and others},
  title   = {{Cohort Profile Update: The ‘Seguimiento Universidad de Navarra’ (SUN) study after 24 years of follow-up}},
  journal = {International Journal of Epidemiology},
  year    = {2025},
  doi     = {10.1093/ije/dyaf149},
  pmid    = {40882668},
  url     = {https://doi.org/10.1093/ije/dyaf149}
}

@article{scheuner1996-8705854,
  author  = {Scheuner, Donalyn and Eckman, Christopher B. and Jensen, M. and Song, X.H. and Citron, Martin and Suzuki, Nobuhiro and Bird, Thomas D. and Hardy, John and Hutton, Melanie L. and Kukull, Walter A. and Larson, Eric B. and Levy‐Lahad, Ephrat and Viitanen, Matti H. and Peskind, Elaine R. and Poorkaj, Parvoneh and Schellenberg, Gerald D. and Tanzi, Rudolph E. and Wasco, Wilma and Lannfelt, Lars and Selkoe, Dennis J. and Younkin, Samuel G.},
  title   = {{Secreted amyloid β–protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease}},
  journal = {Nature Medicine},
  year    = {1996},
  doi     = {10.1038/nm0896-864},
  pmid    = {8705854},
  url     = {https://doi.org/10.1038/nm0896-864}
}

@article{griciuc2013-23623698,
  author  = {Griciuc, Ana and Serrano‐Pozo, Alberto and Parrado, Antonio and Lesinski, Andrea N. and Asselin, Caroline and Mullin, Kristina and Hooli, Basavaraj V. and Choi, Se Hoon and Hyman, Bradley T. and Tanzi, Rudolph E.},
  title   = {{Alzheimer’s Disease Risk Gene CD33 Inhibits Microglial Uptake of Amyloid Beta}},
  journal = {Neuron},
  year    = {2013},
  doi     = {10.1016/j.neuron.2013.04.014},
  pmid    = {23623698},
  url     = {https://doi.org/10.1016/j.neuron.2013.04.014}
}

@article{wolfe1999-10206644,
  author  = {Wolfe, Michael S. and Xia, Weiming and Ostaszewski, Beth L. and Diehl, Thekla S. and Kimberly, William Taylor and Selkoe, Dennis J.},
  title   = {{Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and γ-secretase activity}},
  journal = {Nature},
  year    = {1999},
  doi     = {10.1038/19077},
  pmid    = {10206644},
  url     = {https://doi.org/10.1038/19077}
}

@article{citron1992-1465129,
  author  = {Citron, Martin and Oltersdorf, Tilman and Haass, Christian and McConlogue, Lisa and Hung, Albert Y. and Seubert, Peter A. and Vigo‐Pelfrey, Carmen and Lieberburg, Ivan M. and Selkoe, Dennis J.},
  title   = {{Mutation of the β-amyloid precursor protein in familial Alzheimer's disease increases β-protein production}},
  journal = {Nature},
  year    = {1992},
  doi     = {10.1038/360672a0},
  pmid    = {1465129},
  url     = {https://doi.org/10.1038/360672a0}
}

@article{liu2025-39903689,
  author  = {Liu, Haiyan and Marsh, Thomas W. and Shi, Xinyu and Renton, Alan Edward and Bowling, Kevin M. and Ziegemeier, Ellen and Wang, Guoqiao and Cao, Yuchen and others},
  title   = {{The landscape of autosomal-dominant Alzheimer’s disease: global distribution and age of onset}},
  journal = {Brain},
  year    = {2025},
  doi     = {10.1093/brain/awaf038},
  pmid    = {39903689},
  url     = {https://doi.org/10.1093/brain/awaf038}
}

@article{tanzi1988-2893290,
  author  = {Tanzi, Rudolph E. and McClatchey, Andrea I. and Lamperti, Edward D. and Villa‐Komaroff, Lydia and Gusella, James F. and Neve, Rachael L.},
  title   = {{Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease}},
  journal = {Nature},
  year    = {1988},
  doi     = {10.1038/331528a0},
  pmid    = {2893290},
  url     = {https://doi.org/10.1038/331528a0}
}

@article{fleisher2015-25580592,
  author  = {Fleisher, A. S. and Chen, K. and Quiroz, Y. T. and Jakimovich, L. J. and Gutierrez Gomez, M. and Langois, C. M. and Langbaum, J. B. and Roontiva, A. and others},
  title   = {{Associations between biomarkers and age in the presenilin 1 E280A autosomal dominant Alzheimer disease kindred: a cross-sectional study}},
  journal = {JAMA neurology},
  year    = {2015},
  doi     = {10.1001/jamaneurol.2014.3314},
  pmid    = {25580592},
  url     = {https://doi.org/10.1001/jamaneurol.2014.3314}
}

@article{nitsch1992-1411529,
  author  = {Nitsch, R. M. and Slack, B. E. and Wurtman, R. J. and Growdon, J. H.},
  title   = {{Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors}},
  journal = {Science (New York, N.Y.)},
  year    = {1992},
  doi     = {10.1126/science.1411529},
  pmid    = {1411529},
  url     = {https://doi.org/10.1126/science.1411529}
}

@article{lemere1996-8837617,
  author  = {Lemere, C. A. and Lopera, F. and Kosik, K. S. and Lendon, C. L. and Ossa, J. and Saido, T. C. and Yamaguchi, H. and Ruiz, A. and others},
  title   = {{The E280A presenilin 1 Alzheimer mutation produces increased A beta 42 deposition and severe cerebellar pathology}},
  journal = {Nature medicine},
  year    = {1996},
  doi     = {10.1038/nm1096-1146},
  pmid    = {8837617},
  url     = {https://doi.org/10.1038/nm1096-1146}
}

@article{leissring2003-14687544,
  author  = {Leissring, M. A. and Farris, W. and Chang, A. Y. and Walsh, D. M. and Wu, X. and Sun, X. and Frosch, M. P. and Selkoe, D. J.},
  title   = {{Enhanced proteolysis of beta-amyloid in APP transgenic mice prevents plaque formation, secondary pathology, and premature death}},
  journal = {Neuron},
  year    = {2003},
  doi     = {10.1016/s0896-6273(03)00787-6},
  pmid    = {14687544},
  url     = {https://doi.org/10.1016/s0896-6273(03)00787-6}
}

@article{lee1998-9623986,
  author  = {Lee, S. J. and Liyanage, U. and Bickel, P. E. and Xia, W. and Lansbury, P. T. and Kosik, K. S.},
  title   = {{A detergent-insoluble membrane compartment contains A beta in vivo}},
  journal = {Nature medicine},
  year    = {1998},
  doi     = {10.1038/nm0698-730},
  pmid    = {9623986},
  url     = {https://doi.org/10.1038/nm0698-730}
}

@article{wolozin1996-8939861,
  author  = {Wolozin, B. and Iwasaki, K. and Vito, P. and Ganjei, J. K. and Lacanà, E. and Sunderland, T. and Zhao, B. and Kusiak, J. W. and others},
  title   = {{Participation of presenilin 2 in apoptosis: enhanced basal activity conferred by an Alzheimer mutation}},
  journal = {Science (New York, N.Y.)},
  year    = {1996},
  doi     = {10.1126/science.274.5293.1710},
  pmid    = {8939861},
  url     = {https://doi.org/10.1126/science.274.5293.1710}
}

@article{schultz2023-37291760,
  author  = {Schultz, S. A. and Shirzadi, Z. and Schultz, A. P. and Liu, L. and Fitzpatrick, C. D. and McDade, E. and Barthelemy, N. R. and Renton, A. and others},
  title   = {{Location of pathogenic variants in PSEN1 impacts progression of cognitive, clinical, and neurodegenerative measures in autosomal-dominant Alzheimer's disease}},
  journal = {Aging cell},
  year    = {2023},
  doi     = {10.1111/acel.13871},
  pmid    = {37291760},
  url     = {https://doi.org/10.1111/acel.13871}
}

@article{mcdade2021-34548654,
  author  = {McDade, E. and Voytyuk, I. and Aisen, P. and Bateman, R. J. and Carrillo, M. C. and De Strooper, B. and Haass, C. and Reiman, E. M. and others},
  title   = {{The case for low-level BACE1 inhibition for the prevention of Alzheimer disease}},
  journal = {Nature reviews. Neurology},
  year    = {2021},
  doi     = {10.1038/s41582-021-00545-1},
  pmid    = {34548654},
  url     = {https://doi.org/10.1038/s41582-021-00545-1}
}

@article{busciglio1993-8446635,
  author  = {Busciglio, J. and Gabuzda, D. H. and Matsudaira, P. and Yankner, B. A.},
  title   = {{Generation of beta-amyloid in the secretory pathway in neuronal and nonneuronal cells}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {1993},
  doi     = {10.1073/pnas.90.5.2092},
  pmid    = {8446635},
  url     = {https://doi.org/10.1073/pnas.90.5.2092}
}

@article{tanzi2001-11683989,
  author  = {Tanzi, R. E. and Bertram, L.},
  title   = {{New frontiers in Alzheimer's disease genetics}},
  journal = {Neuron},
  year    = {2001},
  doi     = {10.1016/s0896-6273(01)00476-7},
  pmid    = {11683989},
  url     = {https://doi.org/10.1016/s0896-6273(01)00476-7}
}

@article{hemming2005-16154999,
  author  = {Hemming, M. L. and Selkoe, D. J.},
  title   = {{Amyloid beta-protein is degraded by cellular angiotensin-converting enzyme (ACE) and elevated by an ACE inhibitor}},
  journal = {The Journal of biological chemistry},
  year    = {2005},
  doi     = {10.1074/jbc.m508460200},
  pmid    = {16154999},
  url     = {https://doi.org/10.1074/jbc.m508460200}
}

@article{sultana2006-15950321,
  author  = {Sultana, R. and Boyd-Kimball, D. and Poon, H. F. and Cai, J. and Pierce, W. M. and Klein, J. B. and Markesbery, W. R. and Zhou, X. Z. and others},
  title   = {{Oxidative modification and down-regulation of Pin1 in Alzheimer's disease hippocampus: A redox proteomics analysis}},
  journal = {Neurobiology of aging},
  year    = {2006},
  doi     = {10.1016/j.neurobiolaging.2005.05.005},
  pmid    = {15950321},
  url     = {https://doi.org/10.1016/j.neurobiolaging.2005.05.005}
}

@article{daniels2026-41709913,
  author  = {Daniels, Alisha J. and McDade, Eric and Llibre‐Guerra, Jorge J. and Xiong, Chengjie and Perrin, Richard J. and Ibáñez, Laura and Supnet‐Bell, Charlene and Cruchaga, Carlos C and others},
  title   = {{15 years of longitudinal genetic, clinical, cognitive, imaging, and biochemical measures in DIAN}},
  journal = {npj Dementia},
  year    = {2026},
  doi     = {10.1038/s44400-025-00047-7},
  pmid    = {41709913},
  url     = {https://doi.org/10.1038/s44400-025-00047-7}
}

@article{selkoe1988-3140239,
  author  = {Selkoe, D. J. and Podlisny, M. B. and Joachim, C. L. and Vickers, E. A. and Lee, G. and Fritz, L. C. and Oltersdorf, T.},
  title   = {{Beta-amyloid precursor protein of Alzheimer disease occurs as 110- to 135-kilodalton membrane-associated proteins in neural and nonneural tissues}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {1988},
  doi     = {10.1073/pnas.85.19.7341},
  pmid    = {3140239},
  url     = {https://doi.org/10.1073/pnas.85.19.7341}
}

@article{rogers1999-10037734,
  author  = {Rogers, J. T. and Leiter, L. M. and McPhee, J. and Cahill, C. M. and Zhan, S. S. and Potter, H. and Nilsson, L. N.},
  title   = {{Translation of the alzheimer amyloid precursor protein mRNA is up-regulated by interleukin-1 through 5'-untranslated region sequences}},
  journal = {The Journal of biological chemistry},
  year    = {1999},
  doi     = {10.1074/jbc.274.10.6421},
  pmid    = {10037734},
  url     = {https://doi.org/10.1074/jbc.274.10.6421}
}

@article{dong2009-19433662,
  author  = {Dong, Y. and Zhang, G. and Zhang, B. and Moir, R. D. and Xia, W. and Marcantonio, E. R. and Culley, D. J. and Crosby, G. and others},
  title   = {{The common inhalational anesthetic sevoflurane induces apoptosis and increases beta-amyloid protein levels}},
  journal = {Archives of neurology},
  year    = {2009},
  doi     = {10.1001/archneurol.2009.48},
  pmid    = {19433662},
  url     = {https://doi.org/10.1001/archneurol.2009.48}
}

@article{vonarnim2005-15749709,
  author  = {von Arnim, C. A. and Kinoshita, A. and Peltan, I. D. and Tangredi, M. M. and Herl, L. and Lee, B. M. and Spoelgen, R. and Hshieh, T. T. and others},
  title   = {{The low density lipoprotein receptor-related protein (LRP) is a novel beta-secretase (BACE1) substrate}},
  journal = {The Journal of biological chemistry},
  year    = {2005},
  doi     = {10.1074/jbc.m414248200},
  pmid    = {15749709},
  url     = {https://doi.org/10.1074/jbc.m414248200}
}

@article{hemming2008-18942891,
  author  = {Hemming, M. L. and Elias, J. E. and Gygi, S. P. and Selkoe, D. J.},
  title   = {{Proteomic profiling of gamma-secretase substrates and mapping of substrate requirements}},
  journal = {PLoS biology},
  year    = {2008},
  doi     = {10.1371/journal.pbio.0060257},
  pmid    = {18942891},
  url     = {https://doi.org/10.1371/journal.pbio.0060257}
}

@article{citron1994-7991571,
  author  = {Citron, M. and Vigo-Pelfrey, C. and Teplow, D. B. and Miller, C. and Schenk, D. and Johnston, J. and Winblad, B. and Venizelos, N. and others},
  title   = {{Excessive production of amyloid beta-protein by peripheral cells of symptomatic and presymptomatic patients carrying the Swedish familial Alzheimer disease mutation}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {1994},
  doi     = {10.1073/pnas.91.25.11993},
  pmid    = {7991571},
  url     = {https://doi.org/10.1073/pnas.91.25.11993}
}

@article{citron1996-8917563,
  author  = {Citron, M. and Diehl, T. S. and Gordon, G. and Biere, A. L. and Seubert, P. and Selkoe, D. J.},
  title   = {{Evidence that the 42- and 40-amino acid forms of amyloid beta protein are generated from the beta-amyloid precursor protein by different protease activities}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {1996},
  doi     = {10.1073/pnas.93.23.13170},
  pmid    = {8917563},
  url     = {https://doi.org/10.1073/pnas.93.23.13170}
}

@article{xie2006-16645451,
  author  = {Xie, Z. and Dong, Y. and Maeda, U. and Alfille, P. and Culley, D. J. and Crosby, G. and Tanzi, R. E.},
  title   = {{The common inhalation anesthetic isoflurane induces apoptosis and increases amyloid beta protein levels}},
  journal = {Anesthesiology},
  year    = {2006},
  doi     = {10.1097/00000542-200605000-00015},
  pmid    = {16645451},
  url     = {https://doi.org/10.1097/00000542-200605000-00015}
}

@article{xia1997-9223340,
  author  = {Xia, W. and Zhang, J. and Perez, R. and Koo, E. H. and Selkoe, D. J.},
  title   = {{Interaction between amyloid precursor protein and presenilins in mammalian cells: implications for the pathogenesis of Alzheimer disease}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {1997},
  doi     = {10.1073/pnas.94.15.8208},
  pmid    = {9223340},
  url     = {https://doi.org/10.1073/pnas.94.15.8208}
}

@article{hemming2007-17760499,
  author  = {Hemming, M. L. and Patterson, M. and Reske-Nielsen, C. and Lin, L. and Isacson, O. and Selkoe, D. J.},
  title   = {{Reducing amyloid plaque burden via ex vivo gene delivery of an Abeta-degrading protease: a novel therapeutic approach to Alzheimer disease}},
  journal = {PLoS medicine},
  year    = {2007},
  doi     = {10.1371/journal.pmed.0040262},
  pmid    = {17760499},
  url     = {https://doi.org/10.1371/journal.pmed.0040262}
}

@article{cho2010-20558735,
  author  = {Cho, H. H. and Cahill, C. M. and Vanderburg, C. R. and Scherzer, C. R. and Wang, B. and Huang, X. and Rogers, J. T.},
  title   = {{Selective translational control of the Alzheimer amyloid precursor protein transcript by iron regulatory protein-1}},
  journal = {The Journal of biological chemistry},
  year    = {2010},
  doi     = {10.1074/jbc.m110.149161},
  pmid    = {20558735},
  url     = {https://doi.org/10.1074/jbc.m110.149161}
}

@article{kook2014-24853300,
  author  = {Kook, S. Y. and Jeong, H. and Kang, M. J. and Park, R. and Shin, H. J. and Han, S. H. and Son, S. M. and Song, H. and others},
  title   = {{Crucial role of calbindin-D28k in the pathogenesis of Alzheimer's disease mouse model}},
  journal = {Cell death and differentiation},
  year    = {2014},
  doi     = {10.1038/cdd.2014.67},
  pmid    = {24853300},
  url     = {https://doi.org/10.1038/cdd.2014.67}
}

@article{xu2014-24441878,
  author  = {Xu, Z. and Dong, Y. and Wang, H. and Culley, D. J. and Marcantonio, E. R. and Crosby, G. and Tanzi, R. E. and Zhang, Y. and others},
  title   = {{Age-dependent postoperative cognitive impairment and Alzheimer-related neuropathology in mice}},
  journal = {Scientific reports},
  year    = {2014},
  doi     = {10.1038/srep03766},
  pmid    = {24441878},
  url     = {https://doi.org/10.1038/srep03766}
}

@article{ostergranite1996-8824314,
  author  = {Oster-Granite, M. L. and McPhie, D. L. and Greenan, J. and Neve, R. L.},
  title   = {{Age-dependent neuronal and synaptic degeneration in mice transgenic for the C terminus of the amyloid precursor protein}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {1996},
  doi     = {10.1523/jneurosci.16-21-06732.1996},
  pmid    = {8824314},
  url     = {https://doi.org/10.1523/jneurosci.16-21-06732.1996}
}

@article{schnoder2016-26663083,
  author  = {Schnöder, L. and Hao, W. and Qin, Y. and Liu, S. and Tomic, I. and Liu, X. and Fassbender, K. and Liu, Y.},
  title   = {{Deficiency of Neuronal p38α MAPK Attenuates Amyloid Pathology in Alzheimer Disease Mouse and Cell Models through Facilitating Lysosomal Degradation of BACE1}},
  journal = {The Journal of biological chemistry},
  year    = {2016},
  doi     = {10.1074/jbc.m115.695916},
  pmid    = {26663083},
  url     = {https://doi.org/10.1074/jbc.m115.695916}
}

@article{benowitz1989-2591522,
  author  = {Benowitz, L. I. and Rodriguez, W. and Paskevich, P. and Mufson, E. J. and Schenk, D. and Neve, R. L.},
  title   = {{The amyloid precursor protein is concentrated in neuronal lysosomes in normal and Alzheimer disease subjects}},
  journal = {Experimental neurology},
  year    = {1989},
  doi     = {10.1016/0014-4886(89)90156-8},
  pmid    = {2591522},
  url     = {https://doi.org/10.1016/0014-4886(89)90156-8}
}

@article{mcphie2003-12890786,
  author  = {McPhie, D. L. and Coopersmith, R. and Hines-Peralta, A. and Chen, Y. and Ivins, K. J. and Manly, S. P. and Kozlowski, M. R. and Neve, K. A. and others},
  title   = {{DNA synthesis and neuronal apoptosis caused by familial Alzheimer disease mutants of the amyloid precursor protein are mediated by the p21 activated kinase PAK3}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2003},
  doi     = {10.1523/jneurosci.23-17-06914.2003},
  pmid    = {12890786},
  url     = {https://doi.org/10.1523/jneurosci.23-17-06914.2003}
}

@article{hoe2009-19164281,
  author  = {Hoe, H. S. and Fu, Z. and Makarova, A. and Lee, J. Y. and Lu, C. and Feng, L. and Pajoohesh-Ganji, A. and Matsuoka, Y. and others},
  title   = {{The effects of amyloid precursor protein on postsynaptic composition and activity}},
  journal = {The Journal of biological chemistry},
  year    = {2009},
  doi     = {10.1074/jbc.m900141200},
  pmid    = {19164281},
  url     = {https://doi.org/10.1074/jbc.m900141200}
}

@article{armstrong2021-33180114,
  author  = {Armstrong, G. W. and Kim, L. A. and Vingopoulos, F. and Park, J. Y. and Garg, I. and Kasetty, M. and Silverman, R. F. and Zeng, R. and others},
  title   = {{Retinal Imaging Findings in Carriers With PSEN1-Associated Early-Onset Familial Alzheimer Disease Before Onset of Cognitive Symptoms}},
  journal = {JAMA ophthalmology},
  year    = {2021},
  doi     = {10.1001/jamaophthalmol.2020.4909},
  pmid    = {33180114},
  url     = {https://doi.org/10.1001/jamaophthalmol.2020.4909}
}

@article{lu2010-20460993,
  author  = {Lu, Y. and Wu, X. and Dong, Y. and Xu, Z. and Zhang, Y. and Xie, Z.},
  title   = {{Anesthetic sevoflurane causes neurotoxicity differently in neonatal naïve and Alzheimer disease transgenic mice}},
  journal = {Anesthesiology},
  year    = {2010},
  doi     = {10.1097/aln.0b013e3181d94de1},
  pmid    = {20460993},
  url     = {https://doi.org/10.1097/aln.0b013e3181d94de1}
}

@article{cataldo1990-2350688,
  author  = {Cataldo, A. M. and Thayer, C. Y. and Bird, E. D. and Wheelock, T. R. and Nixon, R. A.},
  title   = {{Lysosomal proteinase antigens are prominently localized within senile plaques of Alzheimer's disease: evidence for a neuronal origin}},
  journal = {Brain research},
  year    = {1990},
  doi     = {10.1016/0006-8993(90)90456-l},
  pmid    = {2350688},
  url     = {https://doi.org/10.1016/0006-8993(90)90456-l}
}

@article{darochasouto2011-21487307,
  author  = {DaRocha-Souto, B. and Scotton, T. C. and Coma, M. and Serrano-Pozo, A. and Hashimoto, T. and Serenó, L. and Rodríguez, M. and Sánchez, B. and others},
  title   = {{Brain oligomeric β-amyloid but not total amyloid plaque burden correlates with neuronal loss and astrocyte inflammatory response in amyloid precursor protein/tau transgenic mice}},
  journal = {Journal of neuropathology and experimental neurology},
  year    = {2011},
  doi     = {10.1097/nen.0b013e318217a118},
  pmid    = {21487307},
  url     = {https://doi.org/10.1097/nen.0b013e318217a118}
}

@article{hung1992-1409654,
  author  = {Hung, A. Y. and Koo, E. H. and Haass, C. and Selkoe, D. J.},
  title   = {{Increased expression of beta-amyloid precursor protein during neuronal differentiation is not accompanied by secretory cleavage}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {1992},
  doi     = {10.1073/pnas.89.20.9439},
  pmid    = {1409654},
  url     = {https://doi.org/10.1073/pnas.89.20.9439}
}

@article{albanus2025-40737431,
  author  = {Albanus, Ricardo D’Oliveira and Finan, Gina M. and Brase, Logan and Sweeney, Nicholas and Kim, Tae Yeon and Chen, Shuo and Ryoo, Yeonsu and others},
  title   = {{Systematic analysis of cellular cross-talk reveals a role for SEMA6D-TREM2 regulating microglial function in Alzheimer’s disease}},
  journal = {Science Translational Medicine},
  year    = {2025},
  doi     = {10.1126/scitranslmed.adx0027},
  pmid    = {40737431},
  url     = {https://doi.org/10.1126/scitranslmed.adx0027}
}

@article{oltersdorf1990-1968460,
  author  = {Oltersdorf, T. and Ward, P. J. and Henriksson, T. and Beattie, E. C. and Neve, R. and Lieberburg, I. and Fritz, L. C.},
  title   = {{The Alzheimer amyloid precursor protein. Identification of a stable intermediate in the biosynthetic/degradative pathway}},
  journal = {The Journal of biological chemistry},
  year    = {1990},
  doi     = {10.1016/s0021-9258(19)39590-0},
  pmid    = {1968460},
  url     = {https://doi.org/10.1016/s0021-9258(19)39590-0}
}

@article{fraser1994-7966323,
  author  = {Fraser, P. E. and McLachlan, D. R. and Surewicz, W. K. and Mizzen, C. A. and Snow, A. D. and Nguyen, J. T. and Kirschner, D. A.},
  title   = {{Conformation and fibrillogenesis of Alzheimer A beta peptides with selected substitution of charged residues}},
  journal = {Journal of molecular biology},
  year    = {1994},
  doi     = {10.1006/jmbi.1994.1704},
  pmid    = {7966323},
  url     = {https://doi.org/10.1006/jmbi.1994.1704}
}

@article{cataldo2004-15330337,
  author  = {Cataldo, A. M. and Peterhoff, C. M. and Schmidt, S. D. and Terio, N. B. and Duff, K. and Beard, M. and Mathews, P. M. and Nixon, R. A.},
  title   = {{Presenilin mutations in familial Alzheimer disease and transgenic mouse models accelerate neuronal lysosomal pathology}},
  journal = {Journal of neuropathology and experimental neurology},
  year    = {2004},
  doi     = {10.1093/jnen/63.8.821},
  pmid    = {15330337},
  url     = {https://doi.org/10.1093/jnen/63.8.821}
}

@article{kinoshita2003-12888553,
  author  = {Kinoshita, A. and Shah, T. and Tangredi, M. M. and Strickland, D. K. and Hyman, B. T.},
  title   = {{The intracellular domain of the low density lipoprotein receptor-related protein modulates transactivation mediated by amyloid precursor protein and Fe65}},
  journal = {The Journal of biological chemistry},
  year    = {2003},
  doi     = {10.1074/jbc.m306403200},
  pmid    = {12888553},
  url     = {https://doi.org/10.1074/jbc.m306403200}
}

@article{yagi2025-40143815,
  author  = {Yagi, Hitomi and Boeck, Myriam and Neilsen, Katherine and Yang, Jay and Ko, Minji and Tomita, Yohei and Negishi, Kazuno and Fu, Zhongjie and others},
  title   = {{Choroidal Neovascularization Is Suppressed With Activation of TREM2 in Mononuclear Phagocytes—Brief Report}},
  journal = {Arteriosclerosis Thrombosis and Vascular Biology},
  year    = {2025},
  doi     = {10.1161/atvbaha.124.321809},
  pmid    = {40143815},
  url     = {https://doi.org/10.1161/atvbaha.124.321809}
}

@article{fraser1993-8515277,
  author  = {Fraser, P. E. and Nguyen, J. T. and McLachlan, D. R. and Abraham, C. R. and Kirschner, D. A.},
  title   = {{Alpha 1-antichymotrypsin binding to Alzheimer A beta peptides is sequence specific and induces fibril disaggregation in vitro}},
  journal = {Journal of neurochemistry},
  year    = {1993},
  doi     = {10.1111/j.1471-4159.1993.tb03568.x},
  pmid    = {8515277},
  url     = {https://doi.org/10.1111/j.1471-4159.1993.tb03568.x}
}

@article{greenberg1994-8041753,
  author  = {Greenberg, S. M. and Koo, E. H. and Selkoe, D. J. and Qiu, W. Q. and Kosik, K. S.},
  title   = {{Secreted beta-amyloid precursor protein stimulates mitogen-activated protein kinase and enhances tau phosphorylation}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {1994},
  doi     = {10.1073/pnas.91.15.7104},
  pmid    = {8041753},
  url     = {https://doi.org/10.1073/pnas.91.15.7104}
}

@article{fisette2012-22303960,
  author  = {Fisette, J. F. and Montagna, D. R. and Mihailescu, M. R. and Wolfe, M. S.},
  title   = {{A G-rich element forms a G-quadruplex and regulates BACE1 mRNA alternative splicing}},
  journal = {Journal of neurochemistry},
  year    = {2012},
  doi     = {10.1111/j.1471-4159.2012.07680.x},
  pmid    = {22303960},
  url     = {https://doi.org/10.1111/j.1471-4159.2012.07680.x}
}

@article{devkota2025-40723827,
  author  = {Devkota, Sujan and Maesako, Masato and Wolfe, Michael S.},
  title   = {{Presenilin-1 Familial Alzheimer Mutations Impair γ-Secretase Cleavage of APP Through Stabilized Enzyme–Substrate Complex Formation}},
  journal = {Biomolecules},
  year    = {2025},
  doi     = {10.3390/biom15070955},
  pmid    = {40723827},
  url     = {https://doi.org/10.3390/biom15070955}
}

@article{bateman2011-21211070,
  author  = {Bateman, R. J. and Aisen, P. S. and De Strooper, B. and Fox, N. C. and Lemere, C. A. and Ringman, J. M. and Salloway, S. and Sperling, R. A. and others},
  title   = {{Autosomal-dominant Alzheimer's disease: a review and proposal for the prevention of Alzheimer's disease}},
  journal = {Alzheimer's research \& therapy},
  year    = {2011},
  doi     = {10.1186/alzrt59},
  pmid    = {21211070},
  url     = {https://doi.org/10.1186/alzrt59}
}

@article{geula1995-8534419,
  author  = {Geula, C. and Mesulam, M. M.},
  title   = {{Cholinesterases and the pathology of Alzheimer disease}},
  journal = {Alzheimer disease and associated disorders},
  year    = {1995},
  doi     = {10.1097/00002093-199501002-00005},
  pmid    = {8534419},
  url     = {https://doi.org/10.1097/00002093-199501002-00005}
}

@article{arafi2025-99d20e91,
  author  = {Arafi, Parnian and Devkota, Sujan and Williams, Emily L. and Maesako, Masato and Wolfe, Michael S.},
  title   = {{Alzheimer-mutant γ-secretase complexes stall amyloid β-peptide production}},
  journal = {eLife},
  year    = {2025},
  doi     = {10.7554/elife.102274.3},
  url     = {https://doi.org/10.7554/elife.102274.3}
}