% alzhub.org library filter % Source: https://alzhub.org/research?category=genetics&year=2023 % 75 entries, in the order the page lists them. Built from alzhub.org's own records. % 0 entries have no readable author in the source record and carry no author field. @article{belloy2023-37930705, author = {Belloy, M. E. and Andrews, S. J. and Le Guen, Y. and Cuccaro, M. and Farrer, L. A. and Napolioni, V. and Greicius, M. D.}, title = {{APOE Genotype and Alzheimer Disease Risk Across Age, Sex, and Population Ancestry}}, journal = {JAMA Neurology}, year = {2023}, doi = {10.1001/jamaneurol.2023.3599}, pmid = {37930705}, url = {https://doi.org/10.1001/jamaneurol.2023.3599} } @article{orr2024-37994989, author = {Orr, Miranda E and Kotkowski, Eithan and Ramirez, Paulino and Bair-Kelps, Darcy and Liu, Qianqian and Brenner, Charles and Schmidt, Mark S and Fox, Peter T and others}, title = {{A randomized placebo-controlled trial of nicotinamide riboside in older adults with mild cognitive impairment}}, journal = {GeroScience}, year = {2024}, doi = {10.1007/s11357-023-00999-9}, pmid = {37994989}, url = {https://doi.org/10.1007/s11357-023-00999-9} } @article{leguen2023-36809323, author = {Le Guen, Y. and Raulin, A. C. and Logue, M. W. and Sherva, R. and Belloy, M. E. and Eger, S. J. and Chen, A. and Kennedy, G. and Kuchenbecker, L. and O'Leary, J. P. and Zhang, R. and Merritt, V. C. and others}, title = {{Association of African Ancestry-Specific APOE Missense Variant R145C With Risk of Alzheimer Disease}}, journal = {JAMA}, year = {2023}, doi = {10.1001/jama.2023.0268}, pmid = {36809323}, url = {https://doi.org/10.1001/jama.2023.0268} } @article{lake2023-37198259, author = {Lake, Julie and Solsberg, Caroline Warly and Kim, Jonggeol Jeffrey and Acosta-Uribe, Juliana and Makarious, Mary B and Li, Zizheng and Levine, Kristin and Heutink, Peter and others}, title = {{Multi-ancestry meta-analysis and fine-mapping in Alzheimer's disease}}, journal = {Molecular psychiatry}, year = {2023}, doi = {10.1038/s41380-023-02089-w}, pmid = {37198259}, url = {https://doi.org/10.1038/s41380-023-02089-w} } @article{mummery2023-37095250, author = {Mummery, C. J. and Börjesson-Hanson, A. and Blackburn, D. J. and Vijverberg, E. G. B. and De Deyn, P. P. and Ducharme, S. and Jonsson, M. and Schneider, A. and Rinne, J. O. and Ludolph, A. C. and Bodenschatz, R. and Kordasiewicz, H. and others}, title = {{Tau-targeting antisense oligonucleotide MAPTRx in mild Alzheimer's disease: a phase 1b, randomized, placebo-controlled trial}}, journal = {Nature Medicine}, year = {2023}, doi = {10.1038/s41591-023-02326-3}, pmid = {37095250}, url = {https://doi.org/10.1038/s41591-023-02326-3} } @article{rubinski2023-36571564, author = {Rubinski, Anna and Frerich, Simon and Malik, Rainer and Franzmeier, Nicolai and Ramirez, Alfredo and Dichgans, Martin and Ewers, Michael}, title = {{Polygenic Effect on Tau Pathology Progression in Alzheimer's Disease}}, journal = {Annals of neurology}, year = {2023}, doi = {10.1002/ana.26588}, pmid = {36571564}, url = {https://doi.org/10.1002/ana.26588} } @article{yu2023-37177856, author = {Yu, C. and Ryan, J. and Orchard, S. G. and Robb, C. and Woods, R. L. and Wolfe, R. and Renton, A. E. and Goate, A. M. and Brodtmann, A. and Shah, R. C. and Chong, T. T. and Sheets, K. and others}, title = {{Validation of newly derived polygenic risk scores for dementia in a prospective study of older individuals}}, journal = {Alzheimer's \& Dementia}, year = {2023}, doi = {10.1002/alz.13113}, pmid = {37177856}, url = {https://doi.org/10.1002/alz.13113} } @article{li2023-37658353, author = {Li, Qingqin S and Francke, Stephan and Snoeys, Jan and Thipphawong, John and Romano, Gary and Novak, Gerald P}, title = {{Genome-wide association study of abnormal elevation of ALT in patients exposed to atabecestat}}, journal = {BMC genomics}, year = {2023}, doi = {10.1186/s12864-023-09625-6}, pmid = {37658353}, url = {https://doi.org/10.1186/s12864-023-09625-6} } @article{verdi2023-37127353, author = {Verdi, S. and Kia, S. M. and Yong, K. X. X. and Tosun, D. and Schott, J. M. and Marquand, A. F. and Cole, J. H.}, title = {{Revealing Individual Neuroanatomical Heterogeneity in Alzheimer Disease Using Neuroanatomical Normative Modeling}}, journal = {Neurology}, year = {2023}, doi = {10.1212/wnl.0000000000207298}, pmid = {37127353}, url = {https://doi.org/10.1212/wnl.0000000000207298} } @article{lopera2023-37188781, author = {Lopera, F. and Marino, C. and Chandrahas, A. S. and O'Hare, M. and Villalba-Moreno, N. D. and Aguillon, D. and Baena, A. and Sanchez, J. S. and Vila-Castelar, C. and Ramirez Gomez, L. and Chmielewska, N. and Oliveira, G. M. and others}, title = {{Resilience to autosomal dominant Alzheimer's disease in a Reelin-COLBOS heterozygous man}}, journal = {Nature Medicine}, year = {2023}, doi = {10.1038/s41591-023-02318-3}, pmid = {37188781}, url = {https://doi.org/10.1038/s41591-023-02318-3} } @article{deklein2023-36823318, author = {de Klein, Niek and Tsai, Ellen A. and Vochteloo, Martijn and Baird, Denis A. and Huang, Yunfeng and Chen, Chia‐Yen and van Dam, Sipko and Oelen, Roy and others}, title = {{Brain expression quantitative trait locus and network analyses reveal downstream effects and putative drivers for brain-related diseases}}, journal = {Nature Genetics}, year = {2023}, doi = {10.1038/s41588-023-01300-6}, pmid = {36823318}, url = {https://doi.org/10.1038/s41588-023-01300-6} } @article{agarwal2023-36889921, author = {Agarwal, P. and Leurgans, S. E. and Agrawal, S. and Aggarwal, N. T. and Cherian, L. J. and James, B. D. and Dhana, K. and others}, title = {{Association of Mediterranean-DASH Intervention for Neurodegenerative Delay and Mediterranean Diets With Alzheimer Disease Pathology}}, journal = {Neurology}, year = {2023}, doi = {10.1212/wnl.0000000000207176}, pmid = {36889921}, url = {https://doi.org/10.1212/wnl.0000000000207176} } @article{brase2023-37085492, author = {Brase, L. and You, S. F. and D'Oliveira Albanus, R. and Del-Aguila, J. L. and Dai, Y. and Novotny, B. C. and Soriano-Tarraga, C. and Dykstra, T. and others}, title = {{Single-nucleus RNA-sequencing of autosomal dominant Alzheimer disease and risk variant carriers}}, journal = {Nature communications}, year = {2023}, doi = {10.1038/s41467-023-37437-5}, pmid = {37085492}, url = {https://doi.org/10.1038/s41467-023-37437-5} } @article{ramanan2023-37279785, author = {Ramanan, Vijay K and Gebre, Robel K and Graff-Radford, Jonathan and Hofrenning, Ekaterina and Algeciras-Schimnich, Alicia and Figdore, Daniel J and Lowe, Val J and Mielke, Michelle M and others}, title = {{Genetic risk scores enhance the diagnostic value of plasma biomarkers of brain amyloidosis}}, journal = {Brain : a journal of neurology}, year = {2023}, doi = {10.1093/brain/awad196}, pmid = {37279785}, url = {https://doi.org/10.1093/brain/awad196} } @article{vivek2023-37926392, author = {Vivek, Sithara and Faul, Jessica and Thyagarajan, Bharat and Guan, Weihua}, title = {{Explainable variational autoencoder (E-VAE) model using genome-wide SNPs to predict dementia}}, journal = {Journal of biomedical informatics}, year = {2023}, doi = {10.1016/j.jbi.2023.104536}, pmid = {37926392}, url = {https://doi.org/10.1016/j.jbi.2023.104536} } @article{sun2023-37264161, author = {Sun, Na and Akay, Leyla Anne and Murdock, Mitchell H and Park, Yongjin and Galiana-Melendez, Fabiola and Bubnys, Adele and Galani, Kyriaki and Mathys, Hansruedi and others}, title = {{Single-nucleus multiregion transcriptomic analysis of brain vasculature in Alzheimer's disease}}, journal = {Nature neuroscience}, year = {2023}, doi = {10.1038/s41593-023-01334-3}, pmid = {37264161}, url = {https://doi.org/10.1038/s41593-023-01334-3} } @article{yang2023-37082508, author = {Yang, Mu and Matan-Lithwick, Stuart and Wang, Yanling and De Jager, Philip L and Bennett, David A and Felsky, Daniel}, title = {{Multi-omic integration via similarity network fusion to detect molecular subtypes of ageing}}, journal = {Brain communications}, year = {2023}, doi = {10.1093/braincomms/fcad110}, pmid = {37082508}, url = {https://doi.org/10.1093/braincomms/fcad110} } @article{li2023-37260021, author = {Li, D. and Farrell, J. J. and Mez, J. and Martin, E. R. and Bush, W. S. and Ruiz, A. and Boada, M. and de Rojas, I. and Mayeux, R. and Haines, J. L. and Vance, M. A. P. and Wang, L. S. and others}, title = {{Novel loci for Alzheimer's disease identified by a genome-wide association study in Ashkenazi Jews}}, journal = {Alzheimer's \& Dementia}, year = {2023}, doi = {10.1002/alz.13117}, pmid = {37260021}, url = {https://doi.org/10.1002/alz.13117} } @article{zhang2023-38094504, author = {Zhang, Junyao and Wang, Yinuo and Zhang, Yingying and Yao, Junyan}, title = {{Genome-wide association study in Alzheimer's disease: a bibliometric and visualization analysis}}, journal = {Frontiers in aging neuroscience}, year = {2023}, doi = {10.3389/fnagi.2023.1290657}, pmid = {38094504}, url = {https://doi.org/10.3389/fnagi.2023.1290657} } @article{schork2023-37661888, author = {Schork, Nicholas J and Elman, Jeremy A and {Alzheimer’s Disease Neuroimaging Initiative}}, title = {{Pathway-Specific Polygenic Risk Scores Correlate with Clinical Status and Alzheimer's Disease-Related Biomarkers}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2023}, doi = {10.3233/jad-230548}, pmid = {37661888}, url = {https://doi.org/10.3233/jad-230548} } @article{he2023-38017580, author = {He, K. Y. and Khramtsova, E. A. and Cabrera-Socorro, A. and Zhang, Y. and Li, S. and Sarver, B. A. J. and Smets, B. and Li, Q. S. and De Muynck, L. and Parrado, A. R. and Lovestone, S. and Black, M. H.}, title = {{Characterization of APOE Christchurch carriers in 455,306 UK Biobank participants}}, journal = {Molecular Neurodegeneration}, year = {2023}, doi = {10.1186/s13024-023-00684-7}, pmid = {38017580}, url = {https://doi.org/10.1186/s13024-023-00684-7} } @article{reitz2023-37024647, author = {Reitz, C. and Pericak-Vance, M. A. and Foroud, T. and Mayeux, R.}, title = {{A global view of the genetic basis of Alzheimer disease}}, journal = {Nature reviews. Neurology}, year = {2023}, doi = {10.1038/s41582-023-00789-z}, pmid = {37024647}, url = {https://doi.org/10.1038/s41582-023-00789-z} } @article{weigand2023-36780762, author = {Weigand, Alexandra J and Ortiz, Gema and Walker, Kayla S and Galasko, Douglas R and Bondi, Mark W and Thomas, Kelsey R and {Alzheimer's Disease Neuroimaging Initiative}}, title = {{APOE differentially moderates cerebrospinal fluid and plasma phosphorylated tau181 associations with multi-domain cognition}}, journal = {Neurobiology of aging}, year = {2023}, doi = {10.1016/j.neurobiolaging.2022.10.016}, pmid = {36780762}, url = {https://doi.org/10.1016/j.neurobiolaging.2022.10.016} } @article{neumann2023-37794492, author = {Neumann, Alexander and Ohlei, Olena and Küçükali, Fahri and Bos, Isabelle J and Timsina, Jigyasha and Vos, Stephanie and Prokopenko, Dmitry and Tijms, Betty M and others}, title = {{Multivariate GWAS of Alzheimer's disease CSF biomarker profiles implies GRIN2D in synaptic functioning}}, journal = {Genome medicine}, year = {2023}, doi = {10.1186/s13073-023-01233-z}, pmid = {37794492}, url = {https://doi.org/10.1186/s13073-023-01233-z} } @article{lai2023-38007651, author = {Lai, Dongbing and Zhang, Michael and Li, Rudong and Zhang, Chi and Zhang, Pengyue and Liu, Yunlong and Gao, Sujuan and Foroud, Tatiana}, title = {{Identifying Genes Associated with Alzheimer's Disease Using Gene-Based Polygenic Risk Score}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2023}, doi = {10.3233/jad-230510}, pmid = {38007651}, url = {https://doi.org/10.3233/jad-230510} } @article{deschepper2023-36747024, author = {De Schepper, S. and Ge, J. Z. and Sierksma, A. and Crowley, G. and Ferreira, L. S. S. and Garceau, D. and Toomey, C. E. and Sokolova, D. and others}, title = {{Perivascular cells induce microglial phagocytic states and synaptic engulfment via SPP1 in mouse models of Alzheimer's disease}}, journal = {Nature neuroscience}, year = {2023}, doi = {10.1038/s41593-023-01257-z}, pmid = {36747024}, url = {https://doi.org/10.1038/s41593-023-01257-z} } @article{xiong2023-37774680, author = {Xiong, X. and James, B. T. and Boix, C. A. and Park, Y. P. and Galani, K. and Victor, M. B. and Sun, N. and Hou, L. and others}, title = {{Epigenomic dissection of Alzheimer's disease pinpoints causal variants and reveals epigenome erosion}}, journal = {Cell}, year = {2023}, doi = {10.1016/j.cell.2023.08.040}, pmid = {37774680}, url = {https://doi.org/10.1016/j.cell.2023.08.040} } @article{zhou2023-36546403, author = {Zhou, Shan and Zhu, Gaizhi and Xu, Yaqi and Gao, Ran and Zhang, Min and Zeng, Qi and Su, Wenting and Wang, Renxi}, title = {{Mendelian randomization study on the causal effect of chickenpox on dementia}}, journal = {Journal of medical virology}, year = {2023}, doi = {10.1002/jmv.28420}, pmid = {36546403}, url = {https://doi.org/10.1002/jmv.28420} } @article{li2023-37824643, author = {Li, Y. E. and Preissl, S. and Miller, M. and Johnson, N. D. and Wang, Z. and Jiao, H. and Zhu, C. and others}, title = {{A comparative atlas of single-cell chromatin accessibility in the human brain}}, journal = {Science (New York, N.Y.)}, year = {2023}, doi = {10.1126/science.adf7044}, pmid = {37824643}, url = {https://doi.org/10.1126/science.adf7044} } @article{meneses2023-36546684, author = {Meneses, Axel D and Koga, Shunsuke and Li, Zonghua and O'Leary, Justin and Li, Fuyao and Chen, Kai and Murakami, Aya and Qiao, Wenhui and others}, title = {{APOE2 Exacerbates TDP-43 Related Toxicity in the Absence of Alzheimer Pathology}}, journal = {Annals of neurology}, year = {2023}, doi = {10.1002/ana.26580}, pmid = {36546684}, url = {https://doi.org/10.1002/ana.26580} } @article{wang2023-37693453, author = {Wang, Yanbing and Sarnowski, Chloé and Lin, Honghuang and Pitsillides, Achilleas N and Heard-Costa, Nancy L and Choi, Seung Hoan and Wang, Dongyu and Bis, Joshua C and others}, title = {{Key variants via Alzheimer's Disease Sequencing Project whole genome sequence data}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2023}, doi = {10.1101/2023.08.28.23294631}, pmid = {37693453}, url = {https://doi.org/10.1101/2023.08.28.23294631} } @article{lundberg2023-37848535, author = {Lundberg, Mischa and Sng, Letitia M F and Szul, Piotr and Dunne, Rob and Bayat, Arash and Burnham, Samantha C and Bauer, Denis C and Twine, Natalie A}, title = {{Novel Alzheimer's disease genes and epistasis identified using machine learning GWAS platform}}, journal = {Scientific reports}, year = {2023}, doi = {10.1038/s41598-023-44378-y}, pmid = {37848535}, url = {https://doi.org/10.1038/s41598-023-44378-y} } @article{kuchroo2023-37147305, author = {Kuchroo, Manik and DiStasio, Marcello and Song, Eric and Calapkulu, Eda and Zhang, Le and Ige, Maryam and Sheth, Amar H and Majdoubi, Abdelilah and others}, title = {{Single-cell analysis reveals inflammatory interactions driving macular degeneration}}, journal = {Nature communications}, year = {2023}, doi = {10.1038/s41467-023-37025-7}, pmid = {37147305}, url = {https://doi.org/10.1038/s41467-023-37025-7} } @article{li2023-37714849, author = {Li, Junhao and Jaiswal, Manoj K and Chien, Jo-Fan and Kozlenkov, Alexey and Jung, Jinyoung and Zhou, Ping and Gardashli, Mahammad and Pregent, Luc J and others}, title = {{Divergent single cell transcriptome and epigenome alterations in ALS and FTD patients with C9orf72 mutation}}, journal = {Nature communications}, year = {2023}, doi = {10.1038/s41467-023-41033-y}, pmid = {37714849}, url = {https://doi.org/10.1038/s41467-023-41033-y} } @article{daly2023-37248224, author = {Daly, James L and Danson, Chris M and Lewis, Philip A and Zhao, Lu and Riccardo, Sara and Di Filippo, Lucio and Cacchiarelli, Davide and Lee, Daehoon and others}, title = {{Multi-omic approach characterises the neuroprotective role of retromer in regulating lysosomal health}}, journal = {Nature communications}, year = {2023}, doi = {10.1038/s41467-023-38719-8}, pmid = {37248224}, url = {https://doi.org/10.1038/s41467-023-38719-8} } @article{andradeguerrero2023-36835161, author = {Andrade-Guerrero, J. and Santiago-Balmaseda, A. and Jeronimo-Aguilar, P. and Vargas-Rodríguez, I. and Cadena-Suárez, A. R. and Sánchez-Garibay, C. and Pozo-Molina, G. and Méndez-Catalá, C. F. and others}, title = {{Alzheimer's Disease: An Updated Overview of Its Genetics}}, journal = {International journal of molecular sciences}, year = {2023}, doi = {10.3390/ijms24043754}, pmid = {36835161}, url = {https://doi.org/10.3390/ijms24043754} } @article{morabito2023-37426759, author = {Morabito, S. and Reese, F. and Rahimzadeh, N. and Miyoshi, E. and Swarup, V.}, title = {{hdWGCNA identifies co-expression networks in high-dimensional transcriptomics data}}, journal = {Cell reports methods}, year = {2023}, doi = {10.1016/j.crmeth.2023.100498}, pmid = {37426759}, url = {https://doi.org/10.1016/j.crmeth.2023.100498} } @article{gazestani2023-37774681, author = {Gazestani, V. and Kamath, T. and Nadaf, N. M. and Dougalis, A. and Burris, S. J. and Rooney, B. and Junkkari, A. and Vanderburg, C. and others}, title = {{Early Alzheimer's disease pathology in human cortex involves transient cell states}}, journal = {Cell}, year = {2023}, doi = {10.1016/j.cell.2023.08.005}, pmid = {37774681}, url = {https://doi.org/10.1016/j.cell.2023.08.005} } @article{zeng2023-36732642, author = {Zeng, H. and Huang, J. and Zhou, H. and Meilandt, W. J. and Dejanovic, B. and Zhou, Y. and Bohlen, C. J. and Lee, S. H. and others}, title = {{Integrative in situ mapping of single-cell transcriptional states and tissue histopathology in a mouse model of Alzheimer's disease}}, journal = {Nature neuroscience}, year = {2023}, doi = {10.1038/s41593-022-01251-x}, pmid = {36732642}, url = {https://doi.org/10.1038/s41593-022-01251-x} } @article{windham2024-37805344, author = {Windham, Ian A and Cohen, Sarah}, title = {{The cell biology of APOE in the brain}}, journal = {Trends in cell biology}, year = {2024}, doi = {10.1016/j.tcb.2023.09.004}, pmid = {37805344}, url = {https://doi.org/10.1016/j.tcb.2023.09.004} } @article{litvinchuk2024-37995685, author = {Litvinchuk, Alexandra and Suh, Jung H and Guo, Jing L and Lin, Karin and Davis, Sonnet S and Bien-Ly, Nga and Tycksen, Eric and Tabor, G Travis and others}, title = {{Amelioration of Tau and ApoE4-linked glial lipid accumulation and neurodegeneration with an LXR agonist}}, journal = {Neuron}, year = {2024}, doi = {10.1016/j.neuron.2023.10.023}, pmid = {37995685}, url = {https://doi.org/10.1016/j.neuron.2023.10.023} } @article{he2024-37697966, author = {He, Mingyue and Lian, Tenghong and Guo, Peng and Zhang, Weijiao and Zhang, Yanan and Huang, Yue and Liu, Gaifen and Guan, Huiying and others}, title = {{The roles of apolipoprotein E ε4 on neuropathology and neuroinflammation in patients with Alzheimer's disease}}, journal = {CNS neuroscience \& therapeutics}, year = {2024}, doi = {10.1111/cns.14440}, pmid = {37697966}, url = {https://doi.org/10.1111/cns.14440} } @article{sun2023-37227619, author = {Sun, Yu-Ying and Wang, Zhun and Huang, Han-Chang}, title = {{Roles of ApoE4 on the Pathogenesis in Alzheimer's Disease and the Potential Therapeutic Approaches}}, journal = {Cellular and molecular neurobiology}, year = {2023}, doi = {10.1007/s10571-023-01365-1}, pmid = {37227619}, url = {https://doi.org/10.1007/s10571-023-01365-1} } @article{eskandarisedighi2023-38115077, author = {Eskandari-Sedighi, Ghazaleh and Blurton-Jones, Mathew}, title = {{Microglial APOE4: more is less and less is more}}, journal = {Molecular neurodegeneration}, year = {2023}, doi = {10.1186/s13024-023-00693-6}, pmid = {38115077}, url = {https://doi.org/10.1186/s13024-023-00693-6} } @article{mah2023-37014788, author = {Mah, Dylan and Zhu, Yanan and Su, Guowei and Zhao, Jing and Canning, Ashely and Gibson, James and Song, Xuehong and Stancanelli, Eduardo and others}, title = {{Apolipoprotein E Recognizes Alzheimer's Disease Associated 3-O Sulfation of Heparan Sulfate}}, journal = {Angewandte Chemie (International ed. in English)}, year = {2023}, doi = {10.1002/anie.202212636}, pmid = {37014788}, url = {https://doi.org/10.1002/anie.202212636} } @article{zhao2023-37686334, author = {Zhao, Tianyu and Zhong, Tangsheng and Zhang, Meishuang and Xu, Yang and Zhang, Ming and Chen, Li}, title = {{Alzheimer's Disease: Causal Effect between Obesity and APOE Gene Polymorphisms}}, journal = {International journal of molecular sciences}, year = {2023}, doi = {10.3390/ijms241713531}, pmid = {37686334}, url = {https://doi.org/10.3390/ijms241713531} } @article{adaku2023-37335131, author = {Adaku, Nneoma and Ostendorf, Benjamin N and Mei, Wenbin and Tavazoie, Sohail F}, title = {{Apolipoprotein E2 Stimulates Protein Synthesis and Promotes Melanoma Progression and Metastasis}}, journal = {Cancer research}, year = {2023}, doi = {10.1158/0008-5472.can-23-1252}, pmid = {37335131}, url = {https://doi.org/10.1158/0008-5472.can-23-1252} } @article{shinohara2023-37414536, author = {Shinohara, Mitsuru and Gheni, Ghupurjan and Hitomi, Junichi and Bu, Guojun and Sato, Naoyuki}, title = {{APOE genotypes modify the obesity paradox in dementia}}, journal = {Journal of neurology, neurosurgery, and psychiatry}, year = {2023}, doi = {10.1136/jnnp-2022-331034}, pmid = {37414536}, url = {https://doi.org/10.1136/jnnp-2022-331034} } @article{stuchellbrereton2023-36749730, author = {Stuchell-Brereton, Melissa D and Zimmerman, Maxwell I and Miller, Justin J and Mallimadugula, Upasana L and Incicco, J Jeremías and Roy, Debjit and Smith, Louis G and Cubuk, Jasmine and others}, title = {{Apolipoprotein E4 has extensive conformational heterogeneity in lipid-free and lipid-bound forms}}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, year = {2023}, doi = {10.1073/pnas.2215371120}, pmid = {36749730}, url = {https://doi.org/10.1073/pnas.2215371120} } @article{hou2023-37040764, author = {Hou, Xianglong and Zhang, Xuexin and Zou, Huan and Guan, Mingfeng and Fu, Chaoying and Wang, Wenyuan and Zhang, Zai-Rong and Geng, Yang and others}, title = {{Differential and substrate-specific inhibition of γ-secretase by the C-terminal region of ApoE2, ApoE3, and ApoE4}}, journal = {Neuron}, year = {2023}, doi = {10.1016/j.neuron.2023.03.024}, pmid = {37040764}, url = {https://doi.org/10.1016/j.neuron.2023.03.024} } @article{davies2023-37600228, author = {Davies, Caitlin and Tulloch, Jane and Yip, Ellie and Currie, Lydia and Colom-Cadena, Marti and Wegmann, Susanne and Hyman, Bradley T and Wilkins, Lewis and others}, title = {{Apolipoprotein E isoform does not influence trans-synaptic spread of tau pathology in a mouse model}}, journal = {Brain and neuroscience advances}, year = {2023}, doi = {10.1177/23982128231191046}, pmid = {37600228}, url = {https://doi.org/10.1177/23982128231191046} } @article{sung2023-37163733, author = {Sung, Jin Hee and Ou, Yang and Barger, Steven W}, title = {{Amyloid β-Peptide Effects on Glucose Regulation Are Dependent on Apolipoprotein E Genotype}}, journal = {eNeuro}, year = {2023}, doi = {10.1523/eneuro.0376-22.2023}, pmid = {37163733}, url = {https://doi.org/10.1523/eneuro.0376-22.2023} } @article{lv2023-37594184, author = {Lv, Shuixin and Zhang, Yusi and Lin, Yingbin and Fang, Wenting and Wang, Yu and Li, Zihang and Lin, Anlan and Dai, Xiaoman and others}, title = {{ApoE4 exacerbates the senescence of hippocampal neurons and spatial cognitive impairment by downregulating acetyl-CoA level}}, journal = {Aging cell}, year = {2023}, doi = {10.1111/acel.13932}, pmid = {37594184}, url = {https://doi.org/10.1111/acel.13932} } @article{chernyaeva2023-37155564, author = {Chernyaeva, Larisa and Ratti, Giorgio and Teirilä, Laura and Fudo, Satoshi and Rankka, Uni and Pelkonen, Anssi and Korhonen, Paula and Leskinen, Katarzyna and others}, title = {{Reduced binding of apoE4 to complement factor H promotes amyloid-β oligomerization and neuroinflammation}}, journal = {EMBO reports}, year = {2023}, doi = {10.15252/embr.202256467}, pmid = {37155564}, url = {https://doi.org/10.15252/embr.202256467} } @article{liemisa2023-38058491, author = {Liemisa, Braison and Newbury, Samantha F and Novy, Mariah J and Pasato, Jonathan A and Morales-Corraliza, Jose and Peng, Katherine Y and Mathews, Paul M}, title = {{Brain apolipoprotein E levels in mice challenged by a Western diet increase in an allele-dependent manner}}, journal = {Aging brain}, year = {2023}, doi = {10.1016/j.nbas.2023.100102}, pmid = {38058491}, url = {https://doi.org/10.1016/j.nbas.2023.100102} } @article{zhang2023-36766752, author = {Zhang, Xin and Wu, Long and Swerdlow, Russell H and Zhao, Liqin}, title = {{Opposing Effects of ApoE2 and ApoE4 on Glycolytic Metabolism in Neuronal Aging Supports a Warburg Neuroprotective Cascade against Alzheimer's Disease}}, journal = {Cells}, year = {2023}, doi = {10.3390/cells12030410}, pmid = {36766752}, url = {https://doi.org/10.3390/cells12030410} } @article{wainberg2023-37328865, author = {Wainberg, Michael and Andrews, Shea J and Tripathy, Shreejoy J}, title = {{Shared genetic risk loci between Alzheimer's disease and related dementias, Parkinson's disease, and amyotrophic lateral sclerosis}}, journal = {Alzheimer's research \& therapy}, year = {2023}, doi = {10.1186/s13195-023-01244-3}, pmid = {37328865}, url = {https://doi.org/10.1186/s13195-023-01244-3} } @article{rajabli2023-38168201, author = {Rajabli, Farid}, title = {{Addressing Overlapping Sample Challenges in Genome-Wide Association Studies: Meta-Reductive Approach}}, journal = {PloS one}, year = {2023}, doi = {10.1101/2023.12.08.570867}, pmid = {38168201}, url = {https://doi.org/10.1101/2023.12.08.570867} } @article{nott2023-37359515, author = {Nott, Alexi and Holtman, Inge R}, title = {{Genetic insights into immune mechanisms of Alzheimer's and Parkinson's disease}}, journal = {Frontiers in immunology}, year = {2023}, doi = {10.3389/fimmu.2023.1168539}, pmid = {37359515}, url = {https://doi.org/10.3389/fimmu.2023.1168539} } @article{janardhanan2023-38028602, author = {Janardhanan, Meghana and Sen, Somdatta and Shankarappa, Bhagylakshmi and Purushottam, Meera}, title = {{Molecular genetics of neuropsychiatric illness: some musings}}, journal = {Frontiers in genetics}, year = {2023}, doi = {10.3389/fgene.2023.1203017}, pmid = {38028602}, url = {https://doi.org/10.3389/fgene.2023.1203017} } @article{besin2023-37211175, author = {Besin, Valentinus and Humardani, Farizky Martriano and Mulyanata, Lisa Thalia}, title = {{Neurogenomics of Alzheimer's disease (AD): An Asian population review}}, journal = {Clinica chimica acta; international journal of clinical chemistry}, year = {2023}, doi = {10.1016/j.cca.2023.117389}, pmid = {37211175}, url = {https://doi.org/10.1016/j.cca.2023.117389} } @article{logue2023-37629231, author = {Logue, Mark W and Dasgupta, Shoumita and Farrer, Lindsay A}, title = {{Genetics of Alzheimer's Disease in the African American Population}}, journal = {Journal of clinical medicine}, year = {2023}, doi = {10.3390/jcm12165189}, pmid = {37629231}, url = {https://doi.org/10.3390/jcm12165189} } @article{praschberger2023-36948206, author = {Praschberger, Roman and Kuenen, Sabine and Schoovaerts, Nils and Kaempf, Natalie and Singh, Jeevanjot and Janssens, Jasper and Swerts, Jef and Nachman, Eliana and others}, title = {{Neuronal identity defines α-synuclein and tau toxicity}}, journal = {Neuron}, year = {2023}, doi = {10.1016/j.neuron.2023.02.033}, pmid = {36948206}, url = {https://doi.org/10.1016/j.neuron.2023.02.033} } @article{anderson2023-36950385, author = {Anderson, Ashlyn G and Rogers, Brianne B and Loupe, Jacob M and Rodriguez-Nunez, Ivan and Roberts, Sydney C and White, Lauren M and Brazell, J Nicholas and Bunney, William E and others}, title = {{Single nucleus multiomics identifies ZEB1 and MAFB as candidate regulators of Alzheimer's disease-specific cis-regulatory elements}}, journal = {Cell genomics}, year = {2023}, doi = {10.1016/j.xgen.2023.100263}, pmid = {36950385}, url = {https://doi.org/10.1016/j.xgen.2023.100263} } @article{yu2023-37925638, author = {Yu, Min and Nie, Yage and Yang, Jiawen and Yang, Shilun and Li, Rui and Rao, Varsha and Hu, Xiaoyan and Fang, Cheng and others}, title = {{Integrative multi-omic profiling of adult mouse brain endothelial cells and potential implications in Alzheimer's disease}}, journal = {Cell reports}, year = {2023}, doi = {10.1016/j.celrep.2023.113392}, pmid = {37925638}, url = {https://doi.org/10.1016/j.celrep.2023.113392} } @article{fan2023-37735671, author = {Fan, Li-Yuan and Yang, Jing and Liu, Ruo-Yu and Kong, Ying and Guo, Guang-Yu and Xu, Yu-Ming}, title = {{Integrating single-nucleus sequence profiling to reveal the transcriptional dynamics of Alzheimer's disease, Parkinson's disease, and multiple sclerosis}}, journal = {Journal of translational medicine}, year = {2023}, doi = {10.1186/s12967-023-04516-6}, pmid = {37735671}, url = {https://doi.org/10.1186/s12967-023-04516-6} } @article{qian2023-37189441, author = {Qian, Zhenwei and Qin, Jinglin and Lai, Yiwen and Zhang, Chen and Zhang, Xiannian}, title = {{Large-Scale Integration of Single-Cell RNA-Seq Data Reveals Astrocyte Diversity and Transcriptomic Modules across Six Central Nervous System Disorders}}, journal = {Biomolecules}, year = {2023}, doi = {10.3390/biom13040692}, pmid = {37189441}, url = {https://doi.org/10.3390/biom13040692} } @article{kwon2023-39329069, author = {Kwon, Sang Ho and Parthiban, Sowmya and Tippani, Madhavi and Divecha, Heena R and Eagles, Nicholas J and Lobana, Jashandeep S and Williams, Stephen R and Mak, Michelle and others}, title = {{Influence of Alzheimer's disease related neuropathology on local microenvironment gene expression in the human inferior temporal cortex}}, journal = {GEN biotechnology}, year = {2023}, doi = {10.1089/genbio.2023.0019}, pmid = {39329069}, url = {https://doi.org/10.1089/genbio.2023.0019} } @article{coleman2023-37684260, author = {Coleman, Claire and Wang, Minghui and Wang, Erming and Micallef, Courtney and Shao, Zhiping and Vicari, James M and Li, Yuxin and Yu, Kaiwen and others}, title = {{Multi-omic atlas of the parahippocampal gyrus in Alzheimer's disease}}, journal = {Scientific data}, year = {2023}, doi = {10.1038/s41597-023-02507-2}, pmid = {37684260}, url = {https://doi.org/10.1038/s41597-023-02507-2} } @article{fan2023-36910261, author = {Fan, Li-Yuan and Yang, Jing and Li, Ming-Li and Liu, Ruo-Yu and Kong, Ying and Duan, Su-Ying and Guo, Guang-Yu and Yang, Jing-Hua and others}, title = {{Single-nucleus transcriptional profiling uncovers the reprogrammed metabolism of astrocytes in Alzheimer's disease}}, journal = {Frontiers in molecular neuroscience}, year = {2023}, doi = {10.3389/fnmol.2023.1136398}, pmid = {36910261}, url = {https://doi.org/10.3389/fnmol.2023.1136398} } @article{sanna2023-37308288, author = {Sanna, Pietro Paolo and Cabrelle, Chiara and Kawamura, Tomoya and Mercatelli, Daniele and O'Connor, Nathan and Roberts, Amanda J and Repunte-Canonigo, Vez and Giorgi, Federico M}, title = {{A History of Repeated Alcohol Intoxication Promotes Cognitive Impairment and Gene Expression Signatures of Disease Progression in the 3xTg Mouse Model of Alzheimer's Disease}}, journal = {eNeuro}, year = {2023}, doi = {10.1523/eneuro.0456-22.2023}, pmid = {37308288}, url = {https://doi.org/10.1523/eneuro.0456-22.2023} } @article{niu2023-36646931, author = {Niu, Muchun and Cao, Wenjian and Wang, Yongcheng and Zhu, Qiangyuan and Luo, Jiayi and Wang, Baiping and Zheng, Hui and Weitz, David A and others}, title = {{Droplet-based transcriptome profiling of individual synapses}}, journal = {Nature biotechnology}, year = {2023}, doi = {10.1038/s41587-022-01635-1}, pmid = {36646931}, url = {https://doi.org/10.1038/s41587-022-01635-1} } @article{sun2023-37774678, author = {Sun, N. and Victor, M. B. and Park, Y. P. and Xiong, X. and Scannail, A. N. and Leary, N. and Prosper, S. and Viswanathan, S. and others}, title = {{Human microglial state dynamics in Alzheimer's disease progression}}, journal = {Cell}, year = {2023}, doi = {10.1016/j.cell.2023.08.037}, pmid = {37774678}, url = {https://doi.org/10.1016/j.cell.2023.08.037} } @article{wu2023-37904974, author = {Wu, Yuchang and Sun, Zhongxuan and Zheng, Qinwen and Miao, Jiacheng and Dorn, Stephen and Mukherjee, Shubhabrata and Fletcher, Jason M and Lu, Qiongshi}, title = {{Pervasive biases in proxy GWAS based on parental history of Alzheimer's disease}}, journal = {bioRxiv : the preprint server for biology}, year = {2023}, doi = {10.1101/2023.10.13.562272}, pmid = {37904974}, url = {https://doi.org/10.1101/2023.10.13.562272} } @article{alvarado2023-37577689, author = {Alvarado, Chelsea X and Weller, Cory A and Johnson, Nicholas and Leonard, Hampton L and Singleton, Andrew B and Reed, Xylena and Blauewendraat, Cornelis and Nalls, Mike}, title = {{Human brain single nucleus cell type enrichments in neurodegenerative diseases}}, journal = {medRxiv : the preprint server for health sciences}, year = {2023}, doi = {10.1101/2023.06.30.23292084}, pmid = {37577689}, url = {https://doi.org/10.1101/2023.06.30.23292084} }