% alzhub.org library filter % Source: https://alzhub.org/research?category=genetics&year=2018 % 68 entries, in the order the page lists them. Built from alzhub.org's own records. % 0 entries have no readable author in the source record and carry no author field. @article{savage2018-29942086, author = {Savage, J. E. and Jansen, P. R. and Stringer, S. and Watanabe, K. and Bryois, J. and de Leeuw, C. A. and Nagel, M. and Awasthi, S. and others}, title = {{Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence}}, journal = {Nature genetics}, year = {2018}, doi = {10.1038/s41588-018-0152-6}, pmid = {29942086}, url = {https://doi.org/10.1038/s41588-018-0152-6} } @article{cai2018-30258348, author = {Cai, Qixuan and Xin, Zhuoyuan and Zuo, Lin and Li, Fan and Liu, Bin}, title = {{Alzheimer's Disease and Rheumatoid Arthritis: A Mendelian Randomization Study}}, journal = {Frontiers in neuroscience}, year = {2018}, doi = {10.3389/fnins.2018.00627}, pmid = {30258348}, url = {https://doi.org/10.3389/fnins.2018.00627} } @article{klimentidis2018-29899525, author = {Klimentidis, Y. C. and Raichlen, D. A. and Bea, J. and Garcia, D. O. and Wineinger, N. E. and Mandarino, L. J. and Alexander, G. E. and Chen, Z. and others}, title = {{Genome-wide association study of habitual physical activity in over 377,000 UK Biobank participants identifies multiple variants including CADM2 and APOE}}, journal = {International journal of obesity (2005)}, year = {2018}, doi = {10.1038/s41366-018-0120-3}, pmid = {29899525}, url = {https://doi.org/10.1038/s41366-018-0120-3} } @article{bergeron2018-30255971, author = {Bergeron, D. and Gorno-Tempini, M. L. and Rabinovici, G. D. and Santos-Santos, M. A. and Seeley, W. and Miller, B. L. and Pijnenburg, Y. and Keulen, M. A. and others}, title = {{Prevalence of amyloid-β pathology in distinct variants of primary progressive aphasia}}, journal = {Annals of neurology}, year = {2018}, doi = {10.1002/ana.25333}, pmid = {30255971}, url = {https://doi.org/10.1002/ana.25333} } @article{hohman2018-29801024, author = {Hohman, T. J. and Dumitrescu, L. and Barnes, L. L. and Thambisetty, M. and Beecham, G. and Kunkle, B. and Gifford, K. A. and Bush, W. S. and others}, title = {{Sex-Specific Association of Apolipoprotein E With Cerebrospinal Fluid Levels of Tau}}, journal = {JAMA neurology}, year = {2018}, doi = {10.1001/jamaneurol.2018.0821}, pmid = {29801024}, url = {https://doi.org/10.1001/jamaneurol.2018.0821} } @article{kern2018-29653987, author = {Kern, S. and Zetterberg, H. and Kern, J. and Zettergren, A. and Waern, M. and Höglund, K. and Andreasson, U. and Wetterberg, H. and others}, title = {{Prevalence of preclinical Alzheimer disease: Comparison of current classification systems}}, journal = {Neurology}, year = {2018}, doi = {10.1212/wnl.0000000000005476}, pmid = {29653987}, url = {https://doi.org/10.1212/wnl.0000000000005476} } @article{brookes2018-29914034, author = {Brookes, Keeley J and McConnell, George and Williams, Kirsty and Chaudhury, Sultan and Madhan, Gaganjit and Patel, Tulsi and Turley, Christopher and Guetta-Baranes, Tamar and others}, title = {{Genotyping of the Alzheimer's Disease Genome-Wide Association Study Index Single Nucleotide Polymorphisms in the Brains for Dementia Research Cohort}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2018}, doi = {10.3233/jad-180191}, pmid = {29914034}, url = {https://doi.org/10.3233/jad-180191} } @article{dejager2018-30084846, author = {De Jager, P. L. and Ma, Y. and McCabe, C. and Xu, J. and Vardarajan, B. N. and Felsky, D. and Klein, H. U. and White, C. C. and others}, title = {{A multi-omic atlas of the human frontal cortex for aging and Alzheimer's disease research}}, journal = {Scientific data}, year = {2018}, doi = {10.1038/sdata.2018.142}, pmid = {30084846}, url = {https://doi.org/10.1038/sdata.2018.142} } @article{weuve2018-28863046, author = {Weuve, J. and Barnes, L. L. and Mendes de Leon, C. F. and Rajan, K. B. and Beck, T. and Aggarwal, N. T. and Hebert, L. E. and Bennett, D. A. and others}, title = {{Cognitive Aging in Black and White Americans: Cognition, Cognitive Decline, and Incidence of Alzheimer Disease Dementia}}, journal = {Epidemiology (Cambridge, Mass.)}, year = {2018}, doi = {10.1097/ede.0000000000000747}, pmid = {28863046}, url = {https://doi.org/10.1097/ede.0000000000000747} } @article{habes2018-30076276, author = {Habes, M. and Sotiras, A. and Erus, G. and Toledo, J. B. and Janowitz, D. and Wolk, D. A. and Shou, H. and Bryan, N. R. and others}, title = {{White matter lesions: Spatial heterogeneity, links to risk factors, cognition, genetics, and atrophy}}, journal = {Neurology}, year = {2018}, doi = {10.1212/wnl.0000000000006116}, pmid = {30076276}, url = {https://doi.org/10.1212/wnl.0000000000006116} } @article{ge2018-29592889, author = {Ge, T. and Sabuncu, M. R. and Smoller, J. W. and Sperling, R. A. and Mormino, E. C. and {Alzheimer's Disease Neuroimaging Initiative}}, title = {{Dissociable influences of APOE ε4 and polygenic risk of AD dementia on amyloid and cognition}}, journal = {Neurology}, year = {2018}, doi = {10.1212/wnl.0000000000005415}, pmid = {29592889}, url = {https://doi.org/10.1212/wnl.0000000000005415} } @article{taylor2018-29546429, author = {Taylor, Adele M. and Pattie, Alison and Deary, Ian J.}, title = {{Cohort Profile Update: The Lothian Birth Cohorts of 1921 and 1936}}, journal = {International Journal of Epidemiology}, year = {2018}, doi = {10.1093/ije/dyy022}, pmid = {29546429}, url = {https://doi.org/10.1093/ije/dyy022} } @article{tao2018-30646251, author = {Tao, Q. and Ang, T. F. A. and DeCarli, C. and Auerbach, S. H. and Devine, S. and Stein, T. D. and Zhang, X. and Massaro, J. and others}, title = {{Association of Chronic Low-grade Inflammation With Risk of Alzheimer Disease in ApoE4 Carriers}}, journal = {JAMA network open}, year = {2018}, doi = {10.1001/jamanetworkopen.2018.3597}, pmid = {30646251}, url = {https://doi.org/10.1001/jamanetworkopen.2018.3597} } @article{rajabli2018-30517106, author = {Rajabli, F. and Feliciano, B. E. and Celis, K. and Hamilton-Nelson, K. L. and Whitehead, P. L. and Adams, L. D. and Bussies, P. L. and Manrique, C. P. and others}, title = {{Ancestral origin of ApoE ε4 Alzheimer disease risk in Puerto Rican and African American populations}}, journal = {PLoS genetics}, year = {2018}, doi = {10.1371/journal.pgen.1007791}, pmid = {30517106}, url = {https://doi.org/10.1371/journal.pgen.1007791} } @article{ruttenjacobs2018-29752348, author = {Rutten-Jacobs, L. C. A. and Tozer, D. J. and Duering, M. and Malik, R. and Dichgans, M. and Markus, H. S. and Traylor, M.}, title = {{Genetic Study of White Matter Integrity in UK Biobank (N=8448) and the Overlap With Stroke, Depression, and Dementia}}, journal = {Stroke}, year = {2018}, doi = {10.1161/strokeaha.118.020811}, pmid = {29752348}, url = {https://doi.org/10.1161/strokeaha.118.020811} } @article{dickson2018-30143564, author = {Dickson, D. W. and Heckman, M. G. and Murray, M. E. and Soto, A. I. and Walton, R. L. and Diehl, N. N. and van Gerpen, J. A. and Uitti, R. J. and others}, title = {{APOE ε4 is associated with severity of Lewy body pathology independent of Alzheimer pathology}}, journal = {Neurology}, year = {2018}, doi = {10.1212/wnl.0000000000006212}, pmid = {30143564}, url = {https://doi.org/10.1212/wnl.0000000000006212} } @article{fischer2018-29966314, author = {Fischer, K. and Melo van Lent, D. and Wolfsgruber, S. and Weinhold, L. and Kleineidam, L. and Bickel, H. and Scherer, M. and Eisele, M. and others}, title = {{Prospective Associations between Single Foods, Alzheimer's Dementia and Memory Decline in the Elderly}}, journal = {Nutrients}, year = {2018}, doi = {10.3390/nu10070852}, pmid = {29966314}, url = {https://doi.org/10.3390/nu10070852} } @article{mishra2018-29672664, author = {Mishra, S. and Blazey, T. M. and Holtzman, D. M. and Cruchaga, C. and Su, Y. and Morris, J. C. and Benzinger, T. L. S. and Gordon, B. A.}, title = {{Longitudinal brain imaging in preclinical Alzheimer disease: impact of APOE ε4 genotype}}, journal = {Brain : a journal of neurology}, year = {2018}, doi = {10.1093/brain/awy103}, pmid = {29672664}, url = {https://doi.org/10.1093/brain/awy103} } @article{hughes2018-29549223, author = {Hughes, T. M. and Wagenknecht, L. E. and Craft, S. and Mintz, A. and Heiss, G. and Palta, P. and Wong, D. and Zhou, Y. and others}, title = {{Arterial stiffness and dementia pathology: Atherosclerosis Risk in Communities (ARIC)-PET Study}}, journal = {Neurology}, year = {2018}, doi = {10.1212/wnl.0000000000005259}, pmid = {29549223}, url = {https://doi.org/10.1212/wnl.0000000000005259} } @article{wennberg2018-30422173, author = {Wennberg, A. M. and Tosakulwong, N. and Lesnick, T. G. and Murray, M. E. and Whitwell, J. L. and Liesinger, A. M. and Petrucelli, L. and Boeve, B. F. and others}, title = {{Association of Apolipoprotein E ε4 With Transactive Response DNA-Binding Protein 43}}, journal = {JAMA neurology}, year = {2018}, doi = {10.1001/jamaneurol.2018.3139}, pmid = {30422173}, url = {https://doi.org/10.1001/jamaneurol.2018.3139} } @article{vardarajan2018-29688227, author = {Vardarajan, Badri N and Barral, Sandra and Jaworski, James and Beecham, Gary W and Blue, Elizabeth and Tosto, Giuseppe and Reyes-Dumeyer, Dolly and Medrano, Martin and others}, title = {{Whole genome sequencing of Caribbean Hispanic families with late-onset Alzheimer's disease}}, journal = {Annals of clinical and translational neurology}, year = {2018}, doi = {10.1002/acn3.537}, pmid = {29688227}, url = {https://doi.org/10.1002/acn3.537} } @article{buckley2018-29803541, author = {Buckley, R. F. and Mormino, E. C. and Amariglio, R. E. and Properzi, M. J. and Rabin, J. S. and Lim, Y. Y. and Papp, K. V. and Jacobs, H. I. L. and others}, title = {{Sex, amyloid, and APOE ε4 and risk of cognitive decline in preclinical Alzheimer's disease: Findings from three well-characterized cohorts}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2018}, doi = {10.1016/j.jalz.2018.04.010}, pmid = {29803541}, url = {https://doi.org/10.1016/j.jalz.2018.04.010} } @article{wang2018-30204156, author = {Wang, M. and Beckmann, N. D. and Roussos, P. and Wang, E. and Zhou, X. and Wang, Q. and Ming, C. and Neff, R. and others}, title = {{The Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer's disease}}, journal = {Scientific data}, year = {2018}, doi = {10.1038/sdata.2018.185}, pmid = {30204156}, url = {https://doi.org/10.1038/sdata.2018.185} } @article{jawinski2019-29703947, author = {Jawinski, Philippe and Kirsten, Holger and Sander, Christian and Spada, Janek and Ulke, Christine and Huang, Jue and Burkhardt, Ralph and Scholz, Markus and others}, title = {{Human brain arousal in the resting state: a genome-wide association study}}, journal = {Molecular psychiatry}, year = {2019}, doi = {10.1038/s41380-018-0052-2}, pmid = {29703947}, url = {https://doi.org/10.1038/s41380-018-0052-2} } @article{dubois2018-29500152, author = {Dubois, B. and Epelbaum, S. and Nyasse, F. and Bakardjian, H. and Gagliardi, G. and Uspenskaya, O. and Houot, M. and Lista, S. and others}, title = {{Cognitive and neuroimaging features and brain β-amyloidosis in individuals at risk of Alzheimer's disease (INSIGHT-preAD): a longitudinal observational study}}, journal = {The Lancet. Neurology}, year = {2018}, doi = {10.1016/s1474-4422(18)30029-2}, pmid = {29500152}, url = {https://doi.org/10.1016/s1474-4422(18)30029-2} } @article{apostolova2018-29340569, author = {Apostolova, L. G. and Risacher, S. L. and Duran, T. and Stage, E. C. and Goukasian, N. and West, J. D. and Do, T. M. and Grotts, J. and others}, title = {{Associations of the Top 20 Alzheimer Disease Risk Variants With Brain Amyloidosis}}, journal = {JAMA neurology}, year = {2018}, doi = {10.1001/jamaneurol.2017.4198}, pmid = {29340569}, url = {https://doi.org/10.1001/jamaneurol.2017.4198} } @article{shi2018-30140051, author = {Shi, Y. and Holtzman, D. M.}, title = {{Interplay between innate immunity and Alzheimer disease: APOE and TREM2 in the spotlight}}, journal = {Nature reviews. Immunology}, year = {2018}, doi = {10.1038/s41577-018-0051-1}, pmid = {30140051}, url = {https://doi.org/10.1038/s41577-018-0051-1} } @article{liao2018-29600961, author = {Liao, F. and Li, A. and Xiong, M. and Bien-Ly, N. and Jiang, H. and Zhang, Y. and Finn, M. B. and Hoyle, R. and others}, title = {{Targeting of nonlipidated, aggregated apoE with antibodies inhibits amyloid accumulation}}, journal = {The Journal of clinical investigation}, year = {2018}, doi = {10.1172/jci96429}, pmid = {29600961}, url = {https://doi.org/10.1172/jci96429} } @article{adams2018-30053297, author = {Adams, J. W. and Alvarez, V. E. and Mez, J. and Huber, B. R. and Tripodis, Y. and Xia, W. and Meng, G. and Kubilus, C. A. and others}, title = {{Lewy Body Pathology and Chronic Traumatic Encephalopathy Associated With Contact Sports}}, journal = {Journal of neuropathology and experimental neurology}, year = {2018}, doi = {10.1093/jnen/nly065}, pmid = {30053297}, url = {https://doi.org/10.1093/jnen/nly065} } @article{farrell2018-30305451, author = {Farrell, M. E. and Chen, X. and Rundle, M. M. and Chan, M. Y. and Wig, G. S. and Park, D. C.}, title = {{Regional amyloid accumulation and cognitive decline in initially amyloid-negative adults}}, journal = {Neurology}, year = {2018}, doi = {10.1212/wnl.0000000000006469}, pmid = {30305451}, url = {https://doi.org/10.1212/wnl.0000000000006469} } @article{quadri2018-29887161, author = {Quadri, M. and Mandemakers, W. and Grochowska, M. M. and Masius, R. and Geut, H. and Fabrizio, E. and Breedveld, G. J. and Kuipers, D. and others}, title = {{LRP10 genetic variants in familial Parkinson's disease and dementia with Lewy bodies: a genome-wide linkage and sequencing study}}, journal = {The Lancet. Neurology}, year = {2018}, doi = {10.1016/s1474-4422(18)30179-0}, pmid = {29887161}, url = {https://doi.org/10.1016/s1474-4422(18)30179-0} } @article{rasmussen2018-30181149, author = {Rasmussen, K. L. and Tybjærg-Hansen, A. and Nordestgaard, B. G. and Frikke-Schmidt, R.}, title = {{Absolute 10-year risk of dementia by age, sex and APOE genotype: a population-based cohort study}}, journal = {CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne}, year = {2018}, doi = {10.1503/cmaj.180066}, pmid = {30181149}, url = {https://doi.org/10.1503/cmaj.180066} } @article{carmona2018-29478590, author = {Carmona, S. and Hardy, J. and Guerreiro, R.}, title = {{The genetic landscape of Alzheimer disease}}, journal = {Handbook of clinical neurology}, year = {2018}, doi = {10.1016/b978-0-444-64076-5.00026-0}, pmid = {29478590}, url = {https://doi.org/10.1016/b978-0-444-64076-5.00026-0} } @article{ping2018-29533394, author = {Ping, L. and Duong, D. M. and Yin, L. and Gearing, M. and Lah, J. J. and Levey, A. I. and Seyfried, N. T.}, title = {{Global quantitative analysis of the human brain proteome in Alzheimer's and Parkinson's Disease}}, journal = {Scientific data}, year = {2018}, doi = {10.1038/sdata.2018.36}, pmid = {29533394}, url = {https://doi.org/10.1038/sdata.2018.36} } @article{wolfe2018-30587772, author = {Wolfe, C. M. and Fitz, N. F. and Nam, K. N. and Lefterov, I. and Koldamova, R.}, title = {{The Role of APOE and TREM2 in Alzheimer's Disease-Current Understanding and Perspectives}}, journal = {International journal of molecular sciences}, year = {2018}, doi = {10.3390/ijms20010081}, pmid = {30587772}, url = {https://doi.org/10.3390/ijms20010081} } @article{karch2018-29630712, author = {Karch, C. M. and Wen, N. and Fan, C. C. and Yokoyama, J. S. and Kouri, N. and Ross, O. A. and Höglinger, G. and Müller, U. and others}, title = {{Selective Genetic Overlap Between Amyotrophic Lateral Sclerosis and Diseases of the Frontotemporal Dementia Spectrum}}, journal = {JAMA neurology}, year = {2018}, doi = {10.1001/jamaneurol.2018.0372}, pmid = {29630712}, url = {https://doi.org/10.1001/jamaneurol.2018.0372} } @article{shokrikojori2018-29632177, author = {Shokri-Kojori, E. and Wang, G. J. and Wiers, C. E. and Demiral, S. B. and Guo, M. and Kim, S. W. and Lindgren, E. and Ramirez, V. and others}, title = {{β-Amyloid accumulation in the human brain after one night of sleep deprivation}}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, year = {2018}, doi = {10.1073/pnas.1721694115}, pmid = {29632177}, url = {https://doi.org/10.1073/pnas.1721694115} } @article{bis2020-30108311, author = {Bis, J. C. and Jian, X. and Kunkle, B. W. and Chen, Y. and Hamilton-Nelson, K. L. and Bush, W. S. and Salerno, W. J. and Lancour, D. and others}, title = {{Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation}}, journal = {Molecular psychiatry}, year = {2020}, doi = {10.1038/s41380-018-0112-7}, pmid = {30108311}, url = {https://doi.org/10.1038/s41380-018-0112-7} } @article{zhu2018-29335400, author = {Zhu, Z. and Zheng, Z. and Zhang, F. and Wu, Y. and Trzaskowski, M. and Maier, R. and Robinson, M. R. and McGrath, J. J. and others}, title = {{Causal associations between risk factors and common diseases inferred from GWAS summary data}}, journal = {Nature communications}, year = {2018}, doi = {10.1038/s41467-017-02317-2}, pmid = {29335400}, url = {https://doi.org/10.1038/s41467-017-02317-2} } @article{olah2018-29416036, author = {Olah, M. and Patrick, E. and Villani, A. C. and Xu, J. and White, C. C. and Ryan, K. J. and Piehowski, P. and Kapasi, A. and others}, title = {{A transcriptomic atlas of aged human microglia}}, journal = {Nature communications}, year = {2018}, doi = {10.1038/s41467-018-02926-5}, pmid = {29416036}, url = {https://doi.org/10.1038/s41467-018-02926-5} } @article{cole2019-29892055, author = {Cole, J. H. and Marioni, R. E. and Harris, S. E. and Deary, I. J.}, title = {{Brain age and other bodily 'ages': implications for neuropsychiatry}}, journal = {Molecular psychiatry}, year = {2019}, doi = {10.1038/s41380-018-0098-1}, pmid = {29892055}, url = {https://doi.org/10.1038/s41380-018-0098-1} } @article{fu2019-30559469, author = {Fu, H. and Possenti, A. and Freer, R. and Nakano, Y. and Hernandez Villegas, N. C. and Tang, M. and Cauhy, P. V. M. and Lassus, B. A. and others}, title = {{A tau homeostasis signature is linked with the cellular and regional vulnerability of excitatory neurons to tau pathology}}, journal = {Nature neuroscience}, year = {2019}, doi = {10.1038/s41593-018-0298-7}, pmid = {30559469}, url = {https://doi.org/10.1038/s41593-018-0298-7} } @article{johnson2018-30286791, author = {Johnson, E. C. B. and Dammer, E. B. and Duong, D. M. and Yin, L. and Thambisetty, M. and Troncoso, J. C. and Lah, J. J. and Levey, A. I. and others}, title = {{Deep proteomic network analysis of Alzheimer's disease brain reveals alterations in RNA binding proteins and RNA splicing associated with disease}}, journal = {Molecular neurodegeneration}, year = {2018}, doi = {10.1186/s13024-018-0282-4}, pmid = {30286791}, url = {https://doi.org/10.1186/s13024-018-0282-4} } @article{finucane2018-29632380, author = {Finucane, Hilary K. and Reshef, Yakir and Anttila, Verneri and Slowikowski, Kamil and Gusev, Alexander and Byrnes, Andrea and Gazal, Steven and Loh, Po‐Ru and others}, title = {{Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types}}, journal = {Nature Genetics}, year = {2018}, doi = {10.1038/s41588-018-0081-4}, pmid = {29632380}, url = {https://doi.org/10.1038/s41588-018-0081-4} } @article{horwitz2019-29942042, author = {Horwitz, Tanya and Lam, Katie and Chen, Yu and Xia, Yan and Liu, Chunyu}, title = {{A decade in psychiatric GWAS research}}, journal = {Molecular psychiatry}, year = {2019}, doi = {10.1038/s41380-018-0055-z}, pmid = {29942042}, url = {https://doi.org/10.1038/s41380-018-0055-z} } @article{hartl2020-29988083, author = {Hartl, Daniela and May, Patrick and Gu, Wei and Mayhaus, Manuel and Pichler, Sabrina and Spaniol, Christian and Glaab, Enrico and Bobbili, Dheeraj Reddy and others}, title = {{A rare loss-of-function variant of ADAM17 is associated with late-onset familial Alzheimer disease}}, journal = {Molecular psychiatry}, year = {2020}, doi = {10.1038/s41380-018-0091-8}, pmid = {29988083}, url = {https://doi.org/10.1038/s41380-018-0091-8} } @article{rangaraju2018-29784049, author = {Rangaraju, S. and Dammer, E. B. and Raza, S. A. and Rathakrishnan, P. and Xiao, H. and Gao, T. and Duong, D. M. and Pennington, M. W. and others}, title = {{Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimer's disease}}, journal = {Molecular neurodegeneration}, year = {2018}, doi = {10.1186/s13024-018-0254-8}, pmid = {29784049}, url = {https://doi.org/10.1186/s13024-018-0254-8} } @article{nativio2018-29507413, author = {Nativio, R. and Donahue, G. and Berson, A. and Lan, Y. and Amlie-Wolf, A. and Tuzer, F. and Toledo, J. B. and Gosai, S. J. and others}, title = {{Dysregulation of the epigenetic landscape of normal aging in Alzheimer's disease}}, journal = {Nature neuroscience}, year = {2018}, doi = {10.1038/s41593-018-0101-9}, pmid = {29507413}, url = {https://doi.org/10.1038/s41593-018-0101-9} } @article{musi2018-30126037, author = {Musi, N. and Valentine, J. M. and Sickora, K. R. and Baeuerle, E. and Thompson, C. S. and Shen, Q. and Orr, M. 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