% alzhub.org library filter % Source: https://alzhub.org/research?category=genetics&year=2017 % 60 entries, in the order the page lists them. Built from alzhub.org's own records. % 0 entries have no readable author in the source record and carry no author field. @article{liu2017-28092683, author = {Liu, J. Z. and Erlich, Y. and Pickrell, J. K.}, title = {{Case-control association mapping by proxy using family history of disease}}, journal = {Nature genetics}, year = {2017}, doi = {10.1038/ng.3766}, pmid = {28092683}, url = {https://doi.org/10.1038/ng.3766} } @article{lupton2017-28582860, author = {Lupton, Michelle K and Benyamin, Beben and Proitsi, Petroula and Nyholt, Dale R and Ferreira, Manuel A and Montgomery, Grant W and Heath, Andrew C and Madden, Pamela A and others}, title = {{No Genetic Overlap Between Circulating Iron Levels and Alzheimer's Disease}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2017}, doi = {10.3233/jad-170027}, pmid = {28582860}, url = {https://doi.org/10.3233/jad-170027} } @article{guerreiro2018-29263008, author = {Guerreiro, R. and Ross, O. A. and Kun-Rodrigues, C. and Hernandez, D. G. and Orme, T. and Eicher, J. D. and Shepherd, C. E. and Parkkinen, L. and others}, title = {{Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study}}, journal = {The Lancet. Neurology}, year = {2018}, doi = {10.1016/s1474-4422(17)30400-3}, pmid = {29263008}, url = {https://doi.org/10.1016/s1474-4422(17)30400-3} } @article{littlejohns2017-28531320, author = {Littlejohns, Thomas J. and Sudlow, Cathie L. M. and Allen, Naomi E. and Collins, Rory}, title = {{UK Biobank: opportunities for cardiovascular research}}, journal = {European Heart Journal}, year = {2017}, doi = {10.1093/eurheartj/ehx254}, pmid = {28531320}, url = {https://doi.org/10.1093/eurheartj/ehx254} } @article{gottesman2017-28399252, author = {Gottesman, R. F. and Schneider, A. L. and Zhou, Y. and Coresh, J. and Green, E. and Gupta, N. and Knopman, D. S. and Mintz, A. and others}, title = {{Association Between Midlife Vascular Risk Factors and Estimated Brain Amyloid Deposition}}, journal = {JAMA}, year = {2017}, doi = {10.1001/jama.2017.3090}, pmid = {28399252}, url = {https://doi.org/10.1001/jama.2017.3090} } @article{neu2017-28846757, author = {Neu, S. C. and Pa, J. and Kukull, W. and Beekly, D. and Kuzma, A. and Gangadharan, P. and Wang, L. S. and Romero, K. and others}, title = {{Apolipoprotein E Genotype and Sex Risk Factors for Alzheimer Disease: A Meta-analysis}}, journal = {JAMA neurology}, year = {2017}, doi = {10.1001/jamaneurol.2017.2188}, pmid = {28846757}, url = {https://doi.org/10.1001/jamaneurol.2017.2188} } @article{deming2017-28247064, author = {Deming, Y. and Li, Z. and Kapoor, M. and Harari, O. and Del-Aguila, J. L. and Black, K. and Carrell, D. and Cai, Y. and others}, title = {{Genome-wide association study identifies four novel loci associated with Alzheimer's endophenotypes and disease modifiers}}, journal = {Acta neuropathologica}, year = {2017}, doi = {10.1007/s00401-017-1685-y}, pmid = {28247064}, url = {https://doi.org/10.1007/s00401-017-1685-y} } @article{nagga2018-29196581, author = {Nägga, K. and Gustavsson, A. M. and Stomrud, E. and Lindqvist, D. and van Westen, D. and Blennow, K. and Zetterberg, H. and Melander, O. and others}, title = {{Increased midlife triglycerides predict brain β-amyloid and tau pathology 20 years later}}, journal = {Neurology}, year = {2018}, doi = {10.1212/wnl.0000000000004749}, pmid = {29196581}, url = {https://doi.org/10.1212/wnl.0000000000004749} } @article{schilling2017-28350817, author = {Schilling, S. and Tzourio, C. and Soumaré, A. and Kaffashian, S. and Dartigues, J. F. and Ancelin, M. L. and Samieri, C. and Dufouil, C. and others}, title = {{Differential associations of plasma lipids with incident dementia and dementia subtypes in the 3C Study: A longitudinal, population-based prospective cohort study}}, journal = {PLoS medicine}, year = {2017}, doi = {10.1371/journal.pmed.1002265}, pmid = {28350817}, url = {https://doi.org/10.1371/journal.pmed.1002265} } @article{pilling2017-29227965, author = {Pilling, L. C. and Kuo, C. L. and Sicinski, K. and Tamosauskaite, J. and Kuchel, G. A. and Harries, L. W. and Herd, P. and Wallace, R. and others}, title = {{Human longevity: 25 genetic loci associated in 389,166 UK biobank participants}}, journal = {Aging}, year = {2017}, doi = {10.18632/aging.101334}, pmid = {29227965}, url = {https://doi.org/10.18632/aging.101334} } @article{shi2017-28959956, author = {Shi, Y. and Yamada, K. and Liddelow, S. A. and Smith, S. T. and Zhao, L. and Luo, W. and Tsai, R. M. and Spina, S. and others}, title = {{ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy}}, journal = {Nature}, year = {2017}, doi = {10.1038/nature24016}, pmid = {28959956}, url = {https://doi.org/10.1038/nature24016} } @article{aarsland2017-28257128, author = {Aarsland, D. and Creese, B. and Politis, M. and Chaudhuri, K. R. and Ffytche, D. H. and Weintraub, D. and Ballard, C.}, title = {{Cognitive decline in Parkinson disease}}, journal = {Nature reviews. Neurology}, year = {2017}, doi = {10.1038/nrneurol.2017.27}, pmid = {28257128}, url = {https://doi.org/10.1038/nrneurol.2017.27} } @article{vemuri2017-28418521, author = {Vemuri, P. and Knopman, D. S. and Lesnick, T. G. and Przybelski, S. A. and Mielke, M. M. and Graff-Radford, J. and Murray, M. E. and Roberts, R. O. and others}, title = {{Evaluation of Amyloid Protective Factors and Alzheimer Disease Neurodegeneration Protective Factors in Elderly Individuals}}, journal = {JAMA neurology}, year = {2017}, doi = {10.1001/jamaneurol.2017.0244}, pmid = {28418521}, url = {https://doi.org/10.1001/jamaneurol.2017.0244} } @article{steele2017-28350795, author = {Steele, N. Z. and Carr, J. S. and Bonham, L. W. and Geier, E. G. and Damotte, V. and Miller, Z. A. and Desikan, R. S. and Boehme, K. L. and others}, title = {{Fine-mapping of the human leukocyte antigen locus as a risk factor for Alzheimer disease: A case-control study}}, journal = {PLoS medicine}, year = {2017}, doi = {10.1371/journal.pmed.1002272}, pmid = {28350795}, url = {https://doi.org/10.1371/journal.pmed.1002272} } @article{qian2017-28323826, author = {Qian, J. and Wolters, F. J. and Beiser, A. and Haan, M. and Ikram, M. A. and Karlawish, J. and Langbaum, J. B. and Neuhaus, J. M. and others}, title = {{APOE-related risk of mild cognitive impairment and dementia for prevention trials: An analysis of four cohorts}}, journal = {PLoS medicine}, year = {2017}, doi = {10.1371/journal.pmed.1002254}, pmid = {28323826}, url = {https://doi.org/10.1371/journal.pmed.1002254} } @article{lafaillemagnan2017-28659431, author = {Lafaille-Magnan, M. E. and Poirier, J. and Etienne, P. and Tremblay-Mercier, J. and Frenette, J. and Rosa-Neto, P. and Breitner, J. C. S. and {PREVENT-AD Research Group}}, title = {{Odor identification as a biomarker of preclinical AD in older adults at risk}}, journal = {Neurology}, year = {2017}, doi = {10.1212/wnl.0000000000004159}, pmid = {28659431}, url = {https://doi.org/10.1212/wnl.0000000000004159} } @article{krellroesch2017-28135351, author = {Krell-Roesch, J. and Vemuri, P. and Pink, A. and Roberts, R. O. and Stokin, G. B. and Mielke, M. M. and Christianson, T. J. and Knopman, D. S. and others}, title = {{Association Between Mentally Stimulating Activities in Late Life and the Outcome of Incident Mild Cognitive Impairment, With an Analysis of the APOE ε4 Genotype}}, journal = {JAMA neurology}, year = {2017}, doi = {10.1001/jamaneurol.2016.3822}, pmid = {28135351}, url = {https://doi.org/10.1001/jamaneurol.2016.3822} } @article{yu2017-28108637, author = {Yu, L. and Lutz, M. W. and Wilson, R. S. and Burns, D. K. and Roses, A. D. and Saunders, A. M. and Gaiteri, C. and De Jager, P. L. and others}, title = {{TOMM40'523 variant and cognitive decline in older persons with APOE ε3/3 genotype}}, journal = {Neurology}, year = {2017}, doi = {10.1212/wnl.0000000000003614}, pmid = {28108637}, url = {https://doi.org/10.1212/wnl.0000000000003614} } @article{nadkarni2017-27842173, author = {Nadkarni, N. K. and Perera, S. and Snitz, B. E. and Mathis, C. A. and Price, J. and Williamson, J. D. and DeKosky, S. T. and Klunk, W. E. and others}, title = {{Association of Brain Amyloid-β With Slow Gait in Elderly Individuals Without Dementia: Influence of Cognition and Apolipoprotein E ε4 Genotype}}, journal = {JAMA neurology}, year = {2017}, doi = {10.1001/jamaneurol.2016.3474}, pmid = {27842173}, url = {https://doi.org/10.1001/jamaneurol.2016.3474} } @article{escottprice2017-28727176, author = {Escott-Price, V. and Myers, A. J. and Huentelman, M. and Hardy, J.}, title = {{Polygenic risk score analysis of pathologically confirmed Alzheimer disease}}, journal = {Annals of neurology}, year = {2017}, doi = {10.1002/ana.24999}, pmid = {28727176}, url = {https://doi.org/10.1002/ana.24999} } @article{mez2017-28983503, author = {Mez, Jesse and Marden, Jessica R and Mukherjee, Shubhabrata and Walter, Stefan and Gibbons, Laura E and Gross, Alden L and Zahodne, Laura B and Gilsanz, Paola and others}, title = {{Alzheimer's disease genetic risk variants beyond APOE ε4 predict mortality}}, journal = {Alzheimer's \& dementia (Amsterdam, Netherlands)}, year = {2017}, doi = {10.1016/j.dadm.2017.07.002}, pmid = {28983503}, url = {https://doi.org/10.1016/j.dadm.2017.07.002} } @article{desikan2017-28323831, author = {Desikan, R. S. and Fan, C. C. and Wang, Y. and Schork, A. J. and Cabral, H. J. and Cupples, L. A. and Thompson, W. K. and Besser, L. and others}, title = {{Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score}}, journal = {PLoS medicine}, year = {2017}, doi = {10.1371/journal.pmed.1002258}, pmid = {28323831}, url = {https://doi.org/10.1371/journal.pmed.1002258} } @article{jun2017-28183528, author = {Jun, G. R. and Chung, J. and Mez, J. and Barber, R. and Beecham, G. W. and Bennett, D. A. and Buxbaum, J. D. and Byrd, G. S. and others}, title = {{Transethnic genome-wide scan identifies novel Alzheimer's disease loci}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2017}, doi = {10.1016/j.jalz.2016.12.012}, pmid = {28183528}, url = {https://doi.org/10.1016/j.jalz.2016.12.012} } @article{slattery2017-28578156, author = {Slattery, C. F. and Zhang, J. and Paterson, R. W. and Foulkes, A. J. M. and Carton, A. and Macpherson, K. and Mancini, L. and Thomas, D. L. and others}, title = {{ApoE influences regional white-matter axonal density loss in Alzheimer's disease}}, journal = {Neurobiology of aging}, year = {2017}, doi = {10.1016/j.neurobiolaging.2017.04.021}, pmid = {28578156}, url = {https://doi.org/10.1016/j.neurobiolaging.2017.04.021} } @article{huynh2017-29216448, author = {Huynh, T. V. and Liao, F. and Francis, C. M. and Robinson, G. O. and Serrano, JR. and Jiang, H. and Roh, J. and Finn, M. B. and others}, title = {{Age-Dependent Effects of apoE Reduction Using Antisense Oligonucleotides in a Model of β-amyloidosis}}, journal = {Neuron}, year = {2017}, doi = {10.1016/j.neuron.2017.11.014}, pmid = {29216448}, url = {https://doi.org/10.1016/j.neuron.2017.11.014} } @article{woodward2017-28243501, author = {Woodward, M. R. and Amrutkar, C. V. and Shah, H. C. and Benedict, R. H. and Rajakrishnan, S. and Doody, R. S. and Yan, L. and Szigeti, K.}, title = {{Validation of olfactory deficit as a biomarker of Alzheimer disease}}, journal = {Neurology. Clinical practice}, year = {2017}, doi = {10.1212/cpj.0000000000000293}, pmid = {28243501}, url = {https://doi.org/10.1212/cpj.0000000000000293} } @article{nsongo2017-28480329, author = {N'Songo, Aurelie and Carrasquillo, Minerva M and Wang, Xue and Burgess, Jeremy D and Nguyen, Thuy and Asmann, Yan W and Serie, Daniel J and Younkin, Steven G and others}, title = {{African American exome sequencing identifies potential risk variants at Alzheimer disease loci}}, journal = {Neurology. Genetics}, year = {2017}, doi = {10.1212/nxg.0000000000000141}, pmid = {28480329}, url = {https://doi.org/10.1212/nxg.0000000000000141} } @article{li2017-28641921, author = {Li, Jin and Zhang, Qiushi and Chen, Feng and Meng, Xianglian and Liu, Wenjie and Chen, Dandan and Yan, Jingwen and Kim, Sungeun and others}, title = {{Genome-wide association and interaction studies of CSF T-tau/Aβ42 ratio in ADNI cohort}}, journal = {Neurobiology of aging}, year = {2017}, doi = {10.1016/j.neurobiolaging.2017.05.007}, pmid = {28641921}, url = {https://doi.org/10.1016/j.neurobiolaging.2017.05.007} } @article{bellenguez2017-28789839, author = {Bellenguez, C. and Charbonnier, C. and Grenier-Boley, B. and Quenez, O. and Le Guennec, K. and Nicolas, G. and Chauhan, G. and Wallon, D. and others}, title = {{Contribution to Alzheimer's disease risk of rare variants in TREM2, SORL1, and ABCA7 in 1779 cases and 1273 controls}}, journal = {Neurobiology of aging}, year = {2017}, doi = {10.1016/j.neurobiolaging.2017.07.001}, pmid = {28789839}, url = {https://doi.org/10.1016/j.neurobiolaging.2017.07.001} } @article{yassine2017-28114437, author = {Yassine, H. N. and Braskie, M. N. and Mack, W. J. and Castor, K. J. and Fonteh, A. N. and Schneider, L. S. and Harrington, M. G. and Chui, H. C.}, title = {{Association of Docosahexaenoic Acid Supplementation With Alzheimer Disease Stage in Apolipoprotein E ε4 Carriers: A Review}}, journal = {JAMA neurology}, year = {2017}, doi = {10.1001/jamaneurol.2016.4899}, pmid = {28114437}, url = {https://doi.org/10.1001/jamaneurol.2016.4899} } @article{holstege2017-28537274, author = {Holstege, H. and van der Lee, S. J. and Hulsman, M. and Wong, T. H. and van Rooij, J. G. and Weiss, M. and Louwersheimer, E. and Wolters, F. J. and others}, title = {{Characterization of pathogenic SORL1 genetic variants for association with Alzheimer's disease: a clinical interpretation strategy}}, journal = {European journal of human genetics : EJHG}, year = {2017}, doi = {10.1038/ejhg.2017.87}, pmid = {28537274}, url = {https://doi.org/10.1038/ejhg.2017.87} } @article{deters2017-28577822, author = {Deters, Kacie D and Nho, Kwangsik and Risacher, Shannon L and Kim, Sungeun and Ramanan, Vijay K and Crane, Paul K and Apostolova, Liana G and Saykin, Andrew J and others}, title = {{Genome-wide association study of language performance in Alzheimer's disease}}, journal = {Brain and language}, year = {2017}, doi = {10.1016/j.bandl.2017.04.008}, pmid = {28577822}, url = {https://doi.org/10.1016/j.bandl.2017.04.008} } @article{lu2017-29220677, author = {Lu, Q. and Li, B. and Ou, D. and Erlendsdottir, M. and Powles, R. L. and Jiang, T. and Hu, Y. and Chang, D. and others}, title = {{A Powerful Approach to Estimating Annotation-Stratified Genetic Covariance via GWAS Summary Statistics}}, journal = {American journal of human genetics}, year = {2017}, doi = {10.1016/j.ajhg.2017.11.001}, pmid = {29220677}, url = {https://doi.org/10.1016/j.ajhg.2017.11.001} } @article{jellinger2018-29222591, author = {Jellinger, K. A.}, title = {{Dementia with Lewy bodies and Parkinson's disease-dementia: current concepts and controversies}}, journal = {Journal of neural transmission (Vienna, Austria : 1996)}, year = {2018}, doi = {10.1007/s00702-017-1821-9}, pmid = {29222591}, url = {https://doi.org/10.1007/s00702-017-1821-9} } @article{calderon2017-29106824, author = {Calderon, D. and Bhaskar, A. and Knowles, D. A. and Golan, D. and Raj, T. and Fu, A. Q. and Pritchard, J. K.}, title = {{Inferring Relevant Cell Types for Complex Traits by Using Single-Cell Gene Expression}}, journal = {American journal of human genetics}, year = {2017}, doi = {10.1016/j.ajhg.2017.09.009}, pmid = {29106824}, url = {https://doi.org/10.1016/j.ajhg.2017.09.009} } @article{huang2017-28735012, author = {Huang, Chao and Thompson, Paul and Wang, Yalin and Yu, Yang and Zhang, Jingwen and Kong, Dehan and Colen, Rivka R and Knickmeyer, Rebecca C and others}, title = {{FGWAS: Functional genome wide association analysis}}, journal = {NeuroImage}, year = {2017}, doi = {10.1016/j.neuroimage.2017.07.030}, pmid = {28735012}, url = {https://doi.org/10.1016/j.neuroimage.2017.07.030} } @article{kovacs2017-28340083, author = {Kovacs, G. G. and Robinson, J. L. and Xie, S. X. and Lee, E. B. and Grossman, M. and Wolk, D. A. and Irwin, D. J. and Weintraub, D. and others}, title = {{Evaluating the Patterns of Aging-Related Tau Astrogliopathy Unravels Novel Insights Into Brain Aging and Neurodegenerative Diseases}}, journal = {Journal of neuropathology and experimental neurology}, year = {2017}, doi = {10.1093/jnen/nlx007}, pmid = {28340083}, url = {https://doi.org/10.1093/jnen/nlx007} } @article{parcon2018-28945989, author = {Parcon, P. A. and Balasubramaniam, M. and Ayyadevara, S. and Jones, R. A. and Liu, L. and Shmookler Reis, R. J. and Barger, S. W. and Mrak, R. E. and others}, title = {{Apolipoprotein E4 inhibits autophagy gene products through direct, specific binding to CLEAR motifs}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2018}, doi = {10.1016/j.jalz.2017.07.754}, pmid = {28945989}, url = {https://doi.org/10.1016/j.jalz.2017.07.754} } @article{michaud2017-28413413, author = {Michaud, T. L. and Su, D. and Siahpush, M. and Murman, D. L.}, title = {{The Risk of Incident Mild Cognitive Impairment and Progression to Dementia Considering Mild Cognitive Impairment Subtypes}}, journal = {Dementia and geriatric cognitive disorders extra}, year = {2017}, doi = {10.1159/000452486}, pmid = {28413413}, url = {https://doi.org/10.1159/000452486} } @article{colomcadena2017-28395086, author = {Colom-Cadena, M. and Grau-Rivera, O. and Planellas, L. and Cerquera, C. and Morenas, E. and Helgueta, S. and Muñoz, L. and Kulisevsky, J. and others}, title = {{Regional Overlap of Pathologies in Lewy Body Disorders}}, journal = {Journal of neuropathology and experimental neurology}, year = {2017}, doi = {10.1093/jnen/nlx002}, pmid = {28395086}, url = {https://doi.org/10.1093/jnen/nlx002} } @article{moser2017-28612048, author = {Moser, V. A. and Pike, C. J.}, title = {{Obesity Accelerates Alzheimer-Related Pathology in APOE4 but not APOE3 Mice}}, journal = {eNeuro}, year = {2017}, doi = {10.1523/eneuro.0077-17.2017}, pmid = {28612048}, url = {https://doi.org/10.1523/eneuro.0077-17.2017} } @article{robert2017-28994390, author = {Robert, Jerome and Button, Emily B and Yuen, Brian and Gilmour, Megan and Kang, Kevin and Bahrabadi, Arvin and Stukas, Sophie and Zhao, Wenchen and others}, title = {{Clearance of beta-amyloid is facilitated by apolipoprotein E and circulating high-density lipoproteins in bioengineered human vessels}}, journal = {eLife}, year = {2017}, doi = {10.7554/elife.29595}, pmid = {28994390}, url = {https://doi.org/10.7554/elife.29595} } @article{sen2017-28569173, author = {Sen, Abhik and Nelson, Thomas J and Alkon, Daniel L}, title = {{ApoE isoforms differentially regulates cleavage and secretion of BDNF}}, journal = {Molecular brain}, year = {2017}, doi = {10.1186/s13041-017-0301-3}, pmid = {28569173}, url = {https://doi.org/10.1186/s13041-017-0301-3} } @article{gause2017-29520379, author = {Gause, J W and Day, R J and Caraway, C A and Poon, W W and Rohn, T T}, title = {{Evaluation of Apolipoprotein E Fragmentation as a Biomarker for Alzheimer's Disease}}, journal = {Journal of neurology and neurological disorders}, year = {2017}, doi = {10.15744/2454-4981.3.204}, pmid = {29520379}, url = {https://doi.org/10.15744/2454-4981.3.204} } @article{estradacuzcano2017-28137957, author = {Estrada-Cuzcano, A. and Martin, S. and Chamova, T. and Synofzik, M. and Timmann, D. and Holemans, T. and Andreeva, A. and Reichbauer, J. and others}, title = {{Loss-of-function mutations in the ATP13A2/PARK9 gene cause complicated hereditary spastic paraplegia (SPG78)}}, journal = {Brain : a journal of neurology}, year = {2017}, doi = {10.1093/brain/aww307}, pmid = {28137957}, url = {https://doi.org/10.1093/brain/aww307} } @article{mathys2017-29020624, author = {Mathys, H. and Adaikkan, C. and Gao, F. and Young, J. 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