% alzhub.org library filter % Source: https://alzhub.org/research?category=genetics&year=2012 % 43 entries, in the order the page lists them. Built from alzhub.org's own records. % 0 entries have no readable author in the source record and carry no author field. @article{coric2012-22892585, author = {Coric, V. and van Dyck, C. H. and Salloway, S. and Andreasen, N. and Brody, M. and Richter, R. W. and Soininen, H. and Thein, S. and others}, title = {{Safety and tolerability of the γ-secretase inhibitor avagacestat in a phase 2 study of mild to moderate Alzheimer disease}}, journal = {Archives of neurology}, year = {2012}, doi = {10.1001/archneurol.2012.2194}, pmid = {22892585}, url = {https://doi.org/10.1001/archneurol.2012.2194} } @article{zou2012-22685416, author = {Zou, F. and Chai, H. S. and Younkin, C. S. and Allen, M. and Crook, J. and Pankratz, V. S. and Carrasquillo, M. M. and Rowley, C. N. and others}, title = {{Brain expression genome-wide association study (eGWAS) identifies human disease-associated variants}}, journal = {PLoS genetics}, year = {2012}, doi = {10.1371/journal.pgen.1002707}, pmid = {22685416}, url = {https://doi.org/10.1371/journal.pgen.1002707} } @article{bettens2012-22248099, author = {Bettens, K. and Brouwers, N. and Engelborghs, S. and Lambert, J. C. and Rogaeva, E. and Vandenberghe, R. and Le Bastard, N. and Pasquier, F. and others}, title = {{Both common variations and rare non-synonymous substitutions and small insertion/deletions in CLU are associated with increased Alzheimer risk}}, journal = {Molecular neurodegeneration}, year = {2012}, doi = {10.1186/1750-1326-7-3}, pmid = {22248099}, url = {https://doi.org/10.1186/1750-1326-7-3} } @article{vanrossum2012-23019259, author = {van Rossum, I. A. and Vos, S. J. and Burns, L. and Knol, D. L. and Scheltens, P. and Soininen, H. and Wahlund, L. O. and Hampel, H. and others}, title = {{Injury markers predict time to dementia in subjects with MCI and amyloid pathology}}, journal = {Neurology}, year = {2012}, doi = {10.1212/wnl.0b013e3182704056}, pmid = {23019259}, url = {https://doi.org/10.1212/wnl.0b013e3182704056} } @article{kamboh2012-22832961, author = {Kamboh, M. I. and Demirci, F. Y. and Wang, X. and Minster, R. L. and Carrasquillo, M. M. and Pankratz, V. S. and Younkin, S. G. and Saykin, A. J. and others}, title = {{Genome-wide association study of Alzheimer's disease}}, journal = {Translational psychiatry}, year = {2012}, doi = {10.1038/tp.2012.45}, pmid = {22832961}, url = {https://doi.org/10.1038/tp.2012.45} } @article{horvath2012-23034122, author = {Horvath, S. and Zhang, Y. and Langfelder, P. and Kahn, R. S. and Boks, M. P. and van Eijk, K. and van den Berg, L. H. and Ophoff, R. A.}, title = {{Aging effects on DNA methylation modules in human brain and blood tissue}}, journal = {Genome biology}, year = {2012}, doi = {10.1186/gb-2012-13-10-r97}, pmid = {23034122}, url = {https://doi.org/10.1186/gb-2012-13-10-r97} } @article{buchman2012-22517108, author = {Buchman, A. S. and Boyle, P. A. and Yu, L. and Shah, R. C. and Wilson, R. S. and Bennett, D. A.}, title = {{Total daily physical activity and the risk of AD and cognitive decline in older adults}}, journal = {Neurology}, year = {2012}, doi = {10.1212/wnl.0b013e3182535d35}, pmid = {22517108}, url = {https://doi.org/10.1212/wnl.0b013e3182535d35} } @article{sperling2012-22305802, author = {Sperling, R. and Salloway, S. and Brooks, D. J. and Tampieri, D. and Barakos, J. and Fox, N. C. and Raskind, M. and Sabbagh, M. and others}, title = {{Amyloid-related imaging abnormalities in patients with Alzheimer's disease treated with bapineuzumab: a retrospective analysis}}, journal = {The Lancet. Neurology}, year = {2012}, doi = {10.1016/s1474-4422(12)70015-7}, pmid = {22305802}, url = {https://doi.org/10.1016/s1474-4422(12)70015-7} } @article{allen2012-22722634, author = {Allen, M. and Zou, F. and Chai, H. S. and Younkin, C. S. and Crook, J. and Pankratz, V. S. and Carrasquillo, M. M. and Rowley, C. N. and others}, title = {{Novel late-onset Alzheimer disease loci variants associate with brain gene expression}}, journal = {Neurology}, year = {2012}, doi = {10.1212/wnl.0b013e3182605801}, pmid = {22722634}, url = {https://doi.org/10.1212/wnl.0b013e3182605801} } @article{dumitriu2012-22761592, author = {Dumitriu, A. and Latourelle, J. C. and Hadzi, T. C. and Pankratz, N. and Garza, D. and Miller, J. P. and Vance, J. M. and Foroud, T. and others}, title = {{Gene expression profiles in Parkinson disease prefrontal cortex implicate FOXO1 and genes under its transcriptional regulation}}, journal = {PLoS genetics}, year = {2012}, doi = {10.1371/journal.pgen.1002794}, pmid = {22761592}, url = {https://doi.org/10.1371/journal.pgen.1002794} } @article{hu2012-22855860, author = {Hu, W. T. and Holtzman, D. M. and Fagan, A. M. and Shaw, L. M. and Perrin, R. and Arnold, S. E. and Grossman, M. and Xiong, C. and others}, title = {{Plasma multianalyte profiling in mild cognitive impairment and Alzheimer disease}}, journal = {Neurology}, year = {2012}, doi = {10.1212/wnl.0b013e318266fa70}, pmid = {22855860}, url = {https://doi.org/10.1212/wnl.0b013e318266fa70} } @article{rodrigue2012-22302550, author = {Rodrigue, K. M. and Kennedy, K. M. and Devous, M. D. and Rieck, JR. and Hebrank, A. C. and Diaz-Arrastia, R. and Mathews, D. and Park, D. C.}, title = {{β-Amyloid burden in healthy aging: regional distribution and cognitive consequences}}, journal = {Neurology}, year = {2012}, doi = {10.1212/wnl.0b013e318245d295}, pmid = {22302550}, url = {https://doi.org/10.1212/wnl.0b013e318245d295} } @article{vanhimbergen2012-22213409, author = {van Himbergen, T. M. and Beiser, A. S. and Ai, M. and Seshadri, S. and Otokozawa, S. and Au, R. and Thongtang, N. and Wolf, P. A. and others}, title = {{Biomarkers for insulin resistance and inflammation and the risk for all-cause dementia and alzheimer disease: results from the Framingham Heart Study}}, journal = {Archives of neurology}, year = {2012}, doi = {10.1001/archneurol.2011.670}, pmid = {22213409}, url = {https://doi.org/10.1001/archneurol.2011.670} } @article{jack2012-22409939, author = {Jack, C. R. and Vemuri, P. and Wiste, H. J. and Weigand, S. D. and Lesnick, T. G. and Lowe, V. and Kantarci, K. and Bernstein, M. A. and others}, title = {{Shapes of the trajectories of 5 major biomarkers of Alzheimer disease}}, journal = {Archives of neurology}, year = {2012}, doi = {10.1001/archneurol.2011.3405}, pmid = {22409939}, url = {https://doi.org/10.1001/archneurol.2011.3405} } @article{mielke2012-22972644, author = {Mielke, M. M. and Wiste, H. J. and Weigand, S. D. and Knopman, D. S. and Lowe, V. J. and Roberts, R. O. and Geda, Y. E. and Swenson-Dravis, D. M. and others}, title = {{Indicators of amyloid burden in a population-based study of cognitively normal elderly}}, journal = {Neurology}, year = {2012}, doi = {10.1212/wnl.0b013e31826e2696}, pmid = {22972644}, url = {https://doi.org/10.1212/wnl.0b013e31826e2696} } @article{vemuri2012-23280791, author = {Vemuri, P. and Lesnick, T. G. and Przybelski, S. A. and Knopman, D. S. and Roberts, R. O. and Lowe, V. J. and Kantarci, K. and Senjem, M. L. and others}, title = {{Effect of lifestyle activities on Alzheimer disease biomarkers and cognition}}, journal = {Annals of neurology}, year = {2012}, doi = {10.1002/ana.23665}, pmid = {23280791}, url = {https://doi.org/10.1002/ana.23665} } @article{allen2012-22494505, author = {Allen, M. and Zou, F. and Chai, H. S. and Younkin, C. S. and Miles, R. and Nair, A. A. and Crook, J. E. and Pankratz, V. S. and others}, title = {{Glutathione S-transferase omega genes in Alzheimer and Parkinson disease risk, age-at-diagnosis and brain gene expression: an association study with mechanistic implications}}, journal = {Molecular neurodegeneration}, year = {2012}, doi = {10.1186/1750-1326-7-13}, pmid = {22494505}, url = {https://doi.org/10.1186/1750-1326-7-13} } @article{barral2012-22539578, author = {Barral, S. and Bird, T. and Goate, A. and Farlow, M. R. and Diaz-Arrastia, R. and Bennett, D. A. and Graff-Radford, N. and Boeve, B. F. and others}, title = {{Genotype patterns at PICALM, CR1, BIN1, CLU, and APOE genes are associated with episodic memory}}, journal = {Neurology}, year = {2012}, doi = {10.1212/wnl.0b013e3182553c48}, pmid = {22539578}, url = {https://doi.org/10.1212/wnl.0b013e3182553c48} } @article{fu2012-23023945, author = {Fu, Rao and Yanjanin, Nicole M and Elrick, Matthew J and Ware, Christopher and Lieberman, Andrew P and Porter, Forbes D}, title = {{Apolipoprotein E genotype and neurological disease onset in Niemann-Pick disease, type C1}}, journal = {American journal of medical genetics. Part A}, year = {2012}, doi = {10.1002/ajmg.a.35395}, pmid = {23023945}, url = {https://doi.org/10.1002/ajmg.a.35395} } @article{ayalew2012-22584867, author = {Ayalew, M. and Le-Niculescu, H. and Levey, D. F. and Jain, N. and Changala, B. and Patel, S. D. and Winiger, E. and Breier, A. and others}, title = {{Convergent functional genomics of schizophrenia: from comprehensive understanding to genetic risk prediction}}, journal = {Molecular psychiatry}, year = {2012}, doi = {10.1038/mp.2012.37}, pmid = {22584867}, url = {https://doi.org/10.1038/mp.2012.37} } @article{seppala2012-22517093, author = {Seppälä, T. T. and Nerg, O. and Koivisto, A. M. and Rummukainen, J. and Puli, L. and Zetterberg, H. and Pyykkö, O. T. and Helisalmi, S. and others}, title = {{CSF biomarkers for Alzheimer disease correlate with cortical brain biopsy findings}}, journal = {Neurology}, year = {2012}, doi = {10.1212/wnl.0b013e3182563bd0}, pmid = {22517093}, url = {https://doi.org/10.1212/wnl.0b013e3182563bd0} } @article{xi2012-22964832, author = {Xi, Z. and Zinman, L. and Grinberg, Y. and Moreno, D. and Sato, C. and Bilbao, J. M. and Ghani, M. and Hernández, I. and others}, title = {{Investigation of c9orf72 in 4 neurodegenerative disorders}}, journal = {Archives of neurology}, year = {2012}, doi = {10.1001/archneurol.2012.2016}, pmid = {22964832}, url = {https://doi.org/10.1001/archneurol.2012.2016} } @article{holtzman2012-22393530, author = {Holtzman, D. M. and Herz, J. and Bu, G.}, title = {{Apolipoprotein E and apolipoprotein E receptors: normal biology and roles in Alzheimer disease}}, journal = {Cold Spring Harbor perspectives in medicine}, year = {2012}, doi = {10.1101/cshperspect.a006312}, pmid = {22393530}, url = {https://doi.org/10.1101/cshperspect.a006312} } @article{tanzi2012-23028126, author = {Tanzi, R. E.}, title = {{The genetics of Alzheimer disease}}, journal = {Cold Spring Harbor perspectives in medicine}, year = {2012}, doi = {10.1101/cshperspect.a006296}, pmid = {23028126}, url = {https://doi.org/10.1101/cshperspect.a006296} } @article{youmans2012-23060451, author = {Youmans, K. L. and Tai, L. M. and Nwabuisi-Heath, E. and Jungbauer, L. and Kanekiyo, T. and Gan, M. and Kim, J. and Eimer, W. A. and others}, title = {{APOE4-specific changes in Aβ accumulation in a new transgenic mouse model of Alzheimer disease}}, journal = {The Journal of biological chemistry}, year = {2012}, doi = {10.1074/jbc.m112.407957}, pmid = {23060451}, url = {https://doi.org/10.1074/jbc.m112.407957} } @article{basak2012-22383525, author = {Basak, J. M. and Verghese, P. B. and Yoon, H. and Kim, J. and Holtzman, D. M.}, title = {{Low-density lipoprotein receptor represents an apolipoprotein E-independent pathway of Aβ uptake and degradation by astrocytes}}, journal = {The Journal of biological chemistry}, year = {2012}, doi = {10.1074/jbc.m111.288746}, pmid = {22383525}, url = {https://doi.org/10.1074/jbc.m111.288746} } @article{xiao2012-22539346, author = {Xiao, Q. and Gil, S. C. and Yan, P. and Wang, Y. and Han, S. and Gonzales, E. and Perez, R. and Cirrito, JR. and others}, title = {{Role of phosphatidylinositol clathrin assembly lymphoid-myeloid leukemia (PICALM) in intracellular amyloid precursor protein (APP) processing and amyloid plaque pathogenesis}}, journal = {The Journal of biological chemistry}, year = {2012}, doi = {10.1074/jbc.m111.338376}, pmid = {22539346}, url = {https://doi.org/10.1074/jbc.m111.338376} } @article{westlye2012-23100402, author = {Westlye, L. T. and Reinvang, I. and Rootwelt, H. and Espeseth, T.}, title = {{Effects of APOE on brain white matter microstructure in healthy adults}}, journal = {Neurology}, year = {2012}, doi = {10.1212/wnl.0b013e3182735c9c}, pmid = {23100402}, url = {https://doi.org/10.1212/wnl.0b013e3182735c9c} } @article{li2012-23132858, author = {Li, J. and Kanekiyo, T. and Shinohara, M. and Zhang, Y. and LaDu, M. J. and Xu, H. and Bu, G.}, title = {{Differential regulation of amyloid-β endocytic trafficking and lysosomal degradation by apolipoprotein E isoforms}}, journal = {The Journal of biological chemistry}, year = {2012}, doi = {10.1074/jbc.m112.420224}, pmid = {23132858}, url = {https://doi.org/10.1074/jbc.m112.420224} } @article{tan2012-23232270, author = {Tan, Lan and Yu, Jin‐Tai and Zhang, Wei and Wu, Zhong‐Chen and Zhang, Qun and Liu, Qiu‐Yan and Wang, Wei and Wang, Hui-Fu and others}, title = {{Association of GWAS‐linked loci with late‐onset Alzheimer's disease in a northern Han Chinese population}}, journal = {Alzheimer s \& Dementia}, year = {2012}, doi = {10.1016/j.jalz.2012.08.007}, pmid = {23232270}, url = {https://doi.org/10.1016/j.jalz.2012.08.007} } @article{jun2012-22869155, author = {Jun, G. and Vardarajan, B. N. and Buros, J. and Yu, C. E. and Hawk, M. V. and Dombroski, B. A. and Crane, P. K. and Larson, E. B. and others}, title = {{Comprehensive search for Alzheimer disease susceptibility loci in the APOE region}}, journal = {Archives of neurology}, year = {2012}, doi = {10.1001/archneurol.2012.2052}, pmid = {22869155}, url = {https://doi.org/10.1001/archneurol.2012.2052} } @article{ossenkoppele2013-23255822, author = {Ossenkoppele, R. and van der Flier, W. M. and Zwan, M. D. and Adriaanse, S. F. and Boellaard, R. and Windhorst, A. D. and Barkhof, F. and Lammertsma, A. A. and others}, title = {{Differential effect of APOE genotype on amyloid load and glucose metabolism in AD dementia}}, journal = {Neurology}, year = {2013}, doi = {10.1212/wnl.0b013e31827f0889}, pmid = {23255822}, url = {https://doi.org/10.1212/wnl.0b013e31827f0889} } @article{cruchaga2012-22821396, author = {Cruchaga, C. and Kauwe, J. S. and Nowotny, P. and Bales, K. and Pickering, E. H. and Mayo, K. and Bertelsen, S. and Hinrichs, A. and others}, title = {{Cerebrospinal fluid APOE levels: an endophenotype for genetic studies for Alzheimer's disease}}, journal = {Human molecular genetics}, year = {2012}, doi = {10.1093/hmg/dds296}, pmid = {22821396}, url = {https://doi.org/10.1093/hmg/dds296} } @article{cramer2012-22323736, author = {Cramer, P. E. and Cirrito, JR. and Wesson, D. W. and Lee, C. Y. and Karlo, J. C. and Zinn, A. E. and Casali, B. T. and Restivo, J. L. and others}, title = {{ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models}}, journal = {Science (New York, N.Y.)}, year = {2012}, doi = {10.1126/science.1217697}, pmid = {22323736}, url = {https://doi.org/10.1126/science.1217697} } @article{lee2013-23193196, author = {Lee, S. H. and Harold, D. and Nyholt, D. R. and {ANZGene Consortium} and {International Endogene Consortium} and {Genetic and Environmental Risk for Alzheimer's disease Consortium} and Goddard, M. E. and Zondervan, K. T. and others}, title = {{Estimation and partitioning of polygenic variation captured by common SNPs for Alzheimer's disease, multiple sclerosis and endometriosis}}, journal = {Human molecular genetics}, year = {2013}, doi = {10.1093/hmg/dds491}, pmid = {23193196}, url = {https://doi.org/10.1093/hmg/dds491} } @article{rao2012-22760556, author = {Rao, J. S. and Keleshian, V. L. and Klein, S. and Rapoport, S. I.}, title = {{Epigenetic modifications in frontal cortex from Alzheimer's disease and bipolar disorder patients}}, journal = {Translational psychiatry}, year = {2012}, doi = {10.1038/tp.2012.55}, pmid = {22760556}, url = {https://doi.org/10.1038/tp.2012.55} } @article{kim2013-22828738, author = {Kim, S. M. and Kim, M. J. and Rhee, H. Y. and Ryu, C. W. and Kim, E. J. and Petersen, E. T. and Jahng, G. H.}, title = {{Regional cerebral perfusion in patients with Alzheimer's disease and mild cognitive impairment: effect of APOE epsilon4 allele}}, journal = {Neuroradiology}, year = {2013}, doi = {10.1007/s00234-012-1077-x}, pmid = {22828738}, url = {https://doi.org/10.1007/s00234-012-1077-x} } @article{mahley2012-23217737, author = {Mahley, Robert W and Huang, Yadong}, title = {{Apolipoprotein e sets the stage: response to injury triggers neuropathology}}, journal = {Neuron}, year = {2012}, doi = {10.1016/j.neuron.2012.11.020}, pmid = {23217737}, url = {https://doi.org/10.1016/j.neuron.2012.11.020} } @article{zhu2012-22228589, author = {Zhu, Yuangui and Nwabuisi-Heath, Evelyn and Dumanis, Sonya B and Tai, Leon M and Yu, Chunjiang and Rebeck, G William and LaDu, Mary Jo}, title = {{APOE genotype alters glial activation and loss of synaptic markers in mice}}, journal = {Glia}, year = {2012}, doi = {10.1002/glia.22289}, pmid = {22228589}, url = {https://doi.org/10.1002/glia.22289} } @article{hitayanez2012-22211488, author = {Hita-Yañez, E. and Atienza, M. and Gil-Neciga, E. and Cantero, J. L.}, title = {{Disturbed sleep patterns in elders with mild cognitive impairment: the role of memory decline and ApoE ε4 genotype}}, journal = {Current Alzheimer research}, year = {2012}, doi = {10.2174/156720512800107609}, pmid = {22211488}, url = {https://doi.org/10.2174/156720512800107609} } @article{talbot2012-22476197, author = {Talbot, K. and Wang, H. Y. and Kazi, H. and Han, L. Y. and Bakshi, K. P. and Stucky, A. and Fuino, R. L. and Kawaguchi, K. R. and others}, title = {{Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline}}, journal = {The Journal of clinical investigation}, year = {2012}, doi = {10.1172/jci59903}, pmid = {22476197}, url = {https://doi.org/10.1172/jci59903} } @article{sultana2013-23044265, author = {Sultana, R. and Perluigi, M. and Butterfield, D. A.}, title = {{Lipid peroxidation triggers neurodegeneration: a redox proteomics view into the Alzheimer disease brain}}, journal = {Free radical biology \& medicine}, year = {2013}, doi = {10.1016/j.freeradbiomed.2012.09.027}, pmid = {23044265}, url = {https://doi.org/10.1016/j.freeradbiomed.2012.09.027} } @article{johnson2012-23098078, author = {Johnson, A. A. and Akman, K. and Calimport, SR. and Wuttke, D. and Stolzing, A. and de Magalhães, J. P.}, title = {{The role of DNA methylation in aging, rejuvenation, and age-related disease}}, journal = {Rejuvenation research}, year = {2012}, doi = {10.1089/rej.2012.1324}, pmid = {23098078}, url = {https://doi.org/10.1089/rej.2012.1324} }