% alzhub.org library filter % Source: https://alzhub.org/research?category=genetics&institution=I180670191 % 46 entries, in the order the page lists them. Built from alzhub.org's own records. % 0 entries have no readable author in the source record and carry no author field. @article{jansen2015-25988462, author = {Jansen, W. J. and Ossenkoppele, R. and Knol, D. L. and Tijms, B. M. and Scheltens, P. and Verhey, F. R. and Visser, P. J. and {Amyloid Biomarker Study Group} and others}, title = {{Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis}}, journal = {JAMA}, year = {2015}, doi = {10.1001/jama.2015.4668}, pmid = {25988462}, url = {https://doi.org/10.1001/jama.2015.4668} } @article{belloy2023-37930705, author = {Belloy, M. E. and Andrews, S. J. and Le Guen, Y. and Cuccaro, M. and Farrer, L. A. and Napolioni, V. and Greicius, M. D.}, title = {{APOE Genotype and Alzheimer Disease Risk Across Age, Sex, and Population Ancestry}}, journal = {JAMA Neurology}, year = {2023}, doi = {10.1001/jamaneurol.2023.3599}, pmid = {37930705}, url = {https://doi.org/10.1001/jamaneurol.2023.3599} } @article{naj2011-21460841, author = {Naj, A. C. and Jun, G. and Beecham, G. W. and Wang, L. S. and Vardarajan, B. N. and Buros, J. and Gallins, P. J. and Buxbaum, J. D. and others}, title = {{Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease}}, journal = {Nature genetics}, year = {2011}, doi = {10.1038/ng.801}, pmid = {21460841}, url = {https://doi.org/10.1038/ng.801} } @article{bergeron2018-30255971, author = {Bergeron, D. and Gorno-Tempini, M. L. and Rabinovici, G. D. and Santos-Santos, M. A. and Seeley, W. and Miller, B. L. and Pijnenburg, Y. and Keulen, M. A. and others}, title = {{Prevalence of amyloid-β pathology in distinct variants of primary progressive aphasia}}, journal = {Annals of neurology}, year = {2018}, doi = {10.1002/ana.25333}, pmid = {30255971}, url = {https://doi.org/10.1002/ana.25333} } @article{jansen2022-36066633, author = {Jansen, I. E. and van der Lee, S. J. and Gomez-Fonseca, D. and de Rojas, I. and Dalmasso, M. C. and Grenier-Boley, B. and Zettergren, A. and Mishra, A. and others}, title = {{Genome-wide meta-analysis for Alzheimer's disease cerebrospinal fluid biomarkers}}, journal = {Acta neuropathologica}, year = {2022}, doi = {10.1007/s00401-022-02454-z}, pmid = {36066633}, url = {https://doi.org/10.1007/s00401-022-02454-z} } @article{naj2014-25199842, author = {Naj, A. C. and Jun, G. and Reitz, C. and Kunkle, B. W. and Perry, W. and Park, Y. S. and Beecham, G. W. and Rajbhandary, R. A. and others}, title = {{Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study}}, journal = {JAMA neurology}, year = {2014}, doi = {10.1001/jamaneurol.2014.1491}, pmid = {25199842}, url = {https://doi.org/10.1001/jamaneurol.2014.1491} } @article{fleisher2011-21917762, author = {Fleisher, A. S. and Truran, D. and Mai, J. T. and Langbaum, J. B. and Aisen, P. S. and Cummings, J. L. and Jack, C. R. and Weiner, M. W. and others}, title = {{Chronic divalproex sodium use and brain atrophy in Alzheimer disease}}, journal = {Neurology}, year = {2011}, doi = {10.1212/wnl.0b013e318230a16c}, pmid = {21917762}, url = {https://doi.org/10.1212/wnl.0b013e318230a16c} } @article{peter2025-40513084, author = {Peter, Christopher and Sathe, Aditi and Shashikumar, Niranjana and Pechman, Kimberly R. and Workmeister, Abigail W. and Jackson, Trevor Bryan and Huo, Yuankai and Mukherjee, Shubhabrata and others}, title = {{White Matter Abnormalities and Cognition in Aging and Alzheimer Disease}}, journal = {JAMA Neurology}, year = {2025}, doi = {10.1001/jamaneurol.2025.1601}, pmid = {40513084}, url = {https://doi.org/10.1001/jamaneurol.2025.1601} } @article{bernath2020-32358220, author = {Bernath, M. M. and Bhattacharyya, S. and Nho, K. and Barupal, D. K. and Fiehn, O. and Baillie, R. and Risacher, S. L. and Arnold, M. and others}, title = {{Serum triglycerides in Alzheimer disease: Relation to neuroimaging and CSF biomarkers}}, journal = {Neurology}, year = {2020}, doi = {10.1212/wnl.0000000000009436}, pmid = {32358220}, url = {https://doi.org/10.1212/wnl.0000000000009436} } @article{ossenkoppele2020-32091549, author = {Ossenkoppele, R. and Lyoo, C. H. and Jester-Broms, J. and Sudre, C. H. and Cho, H. and Ryu, Y. H. and Choi, J. Y. and Smith, R. and others}, title = {{Assessment of Demographic, Genetic, and Imaging Variables Associated With Brain Resilience and Cognitive Resilience to Pathological Tau in Patients With Alzheimer Disease}}, journal = {JAMA neurology}, year = {2020}, doi = {10.1001/jamaneurol.2019.5154}, pmid = {32091549}, url = {https://doi.org/10.1001/jamaneurol.2019.5154} } @article{shi2017-28959956, author = {Shi, Y. and Yamada, K. and Liddelow, S. A. and Smith, S. T. and Zhao, L. and Luo, W. and Tsai, R. M. and Spina, S. and others}, title = {{ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy}}, journal = {Nature}, year = {2017}, doi = {10.1038/nature24016}, pmid = {28959956}, url = {https://doi.org/10.1038/nature24016} } @article{donohue2014-24886908, author = {Donohue, M. C. and Sperling, R. A. and Salmon, D. P. and Rentz, D. M. and Raman, R. and Thomas, R. G. and Weiner, M. and Aisen, P. S. and others}, title = {{The preclinical Alzheimer cognitive composite: measuring amyloid-related decline}}, journal = {JAMA neurology}, year = {2014}, doi = {10.1001/jamaneurol.2014.803}, pmid = {24886908}, url = {https://doi.org/10.1001/jamaneurol.2014.803} } @article{harrison2019-30597624, author = {Harrison, T. M. and La Joie, R. and Maass, A. and Baker, S. L. and Swinnerton, K. and Fenton, L. and Mellinger, T. J. and Edwards, L. and others}, title = {{Longitudinal tau accumulation and atrophy in aging and alzheimer disease}}, journal = {Annals of neurology}, year = {2019}, doi = {10.1002/ana.25406}, pmid = {30597624}, url = {https://doi.org/10.1002/ana.25406} } @article{steele2017-28350795, author = {Steele, N. Z. and Carr, J. S. and Bonham, L. W. and Geier, E. G. and Damotte, V. and Miller, Z. A. and Desikan, R. S. and Boehme, K. L. and others}, title = {{Fine-mapping of the human leukocyte antigen locus as a risk factor for Alzheimer disease: A case-control study}}, journal = {PLoS medicine}, year = {2017}, doi = {10.1371/journal.pmed.1002272}, pmid = {28350795}, url = {https://doi.org/10.1371/journal.pmed.1002272} } @article{raya2026-41729539, author = {Raya, Maison Abu and Suemoto, Claudia Kimie and Paes, Vitor Ribeiro and Leite, Renata Elaine Paraizo and Pasqualucci, Carlos Augusto and Naslavsky, Michel Satya and Rodriguez, Roberta Diehl and Nitrini, Ricardo and others}, title = {{Sex Differences in Amyloid Pathology by Race, Ancestry, and Apolipoprotein E ε4 in an Admixed Autopsy Sample}}, journal = {JAMA neurology}, year = {2026}, doi = {10.1001/jamaneurol.2026.0054}, pmid = {41729539}, url = {https://doi.org/10.1001/jamaneurol.2026.0054} } @article{qian2017-28323826, author = {Qian, J. and Wolters, F. J. and Beiser, A. and Haan, M. and Ikram, M. A. and Karlawish, J. and Langbaum, J. B. and Neuhaus, J. M. and others}, title = {{APOE-related risk of mild cognitive impairment and dementia for prevention trials: An analysis of four cohorts}}, journal = {PLoS medicine}, year = {2017}, doi = {10.1371/journal.pmed.1002254}, pmid = {28323826}, url = {https://doi.org/10.1371/journal.pmed.1002254} } @article{delcampo2016-26643548, author = {Del Campo, N. and Payoux, P. and Djilali, A. and Delrieu, J. and Hoogendijk, E. O. and Rolland, Y. and Cesari, M. and Weiner, M. W. and others}, title = {{Relationship of regional brain β-amyloid to gait speed}}, journal = {Neurology}, year = {2016}, doi = {10.1212/wnl.0000000000002235}, pmid = {26643548}, url = {https://doi.org/10.1212/wnl.0000000000002235} } @article{sperling2012-22305802, author = {Sperling, R. and Salloway, S. and Brooks, D. J. and Tampieri, D. and Barakos, J. and Fox, N. C. and Raskind, M. and Sabbagh, M. and others}, title = {{Amyloid-related imaging abnormalities in patients with Alzheimer's disease treated with bapineuzumab: a retrospective analysis}}, journal = {The Lancet. Neurology}, year = {2012}, doi = {10.1016/s1474-4422(12)70015-7}, pmid = {22305802}, url = {https://doi.org/10.1016/s1474-4422(12)70015-7} } @article{duchowny2022-35737388, author = {Duchowny, K. A. and Ackley, S. F. and Brenowitz, W. D. and Wang, J. and Zimmerman, S. C. and Caunca, M. R. and Glymour, M. M.}, title = {{Associations Between Handgrip Strength and Dementia Risk, Cognition, and Neuroimaging Outcomes in the UK Biobank Cohort Study}}, journal = {JAMA network open}, year = {2022}, doi = {10.1001/jamanetworkopen.2022.18314}, pmid = {35737388}, url = {https://doi.org/10.1001/jamanetworkopen.2022.18314} } @article{toledo2015-25822737, author = {Toledo, J. B. and Bjerke, M. and Da, X. and Landau, S. M. and Foster, N. L. and Jagust, W. and Jack, C. and Weiner, M. and others}, title = {{Nonlinear Association Between Cerebrospinal Fluid and Florbetapir F-18 β-Amyloid Measures Across the Spectrum of Alzheimer Disease}}, journal = {JAMA neurology}, year = {2015}, doi = {10.1001/jamaneurol.2014.4829}, pmid = {25822737}, url = {https://doi.org/10.1001/jamaneurol.2014.4829} } @article{chiang2010-20980669, author = {Chiang, G. C. and Insel, P. S. and Tosun, D. and Schuff, N. and Truran-Sacrey, D. and Raptentsetsang, S. T. and Jack, C. R. and Aisen, P. S. and others}, title = {{Hippocampal atrophy rates and CSF biomarkers in elderly APOE2 normal subjects}}, journal = {Neurology}, year = {2010}, doi = {10.1212/wnl.0b013e3181ffe4d1}, pmid = {20980669}, url = {https://doi.org/10.1212/wnl.0b013e3181ffe4d1} } @article{protas2013-23599929, author = {Protas, H. D. and Chen, K. and Langbaum, J. B. and Fleisher, A. S. and Alexander, G. E. and Lee, W. and Bandy, D. and de Leon, M. J. and others}, title = {{Posterior cingulate glucose metabolism, hippocampal glucose metabolism, and hippocampal volume in cognitively normal, late-middle-aged persons at 3 levels of genetic risk for Alzheimer disease}}, journal = {JAMA neurology}, year = {2013}, doi = {10.1001/2013.jamaneurol.286}, pmid = {23599929}, url = {https://doi.org/10.1001/2013.jamaneurol.286} } @article{yokoyama2016-27088644, author = {Yokoyama, J. S. and Wang, Y. and Schork, A. J. and Thompson, W. K. and Karch, C. M. and Cruchaga, C. and McEvoy, L. K. and Witoelar, A. and others}, title = {{Association Between Genetic Traits for Immune-Mediated Diseases and Alzheimer Disease}}, journal = {JAMA neurology}, year = {2016}, doi = {10.1001/jamaneurol.2016.0150}, pmid = {27088644}, url = {https://doi.org/10.1001/jamaneurol.2016.0150} } @article{jack2012-22409939, author = {Jack, C. R. and Vemuri, P. and Wiste, H. J. and Weigand, S. D. and Lesnick, T. G. and Lowe, V. and Kantarci, K. and Bernstein, M. A. and others}, title = {{Shapes of the trajectories of 5 major biomarkers of Alzheimer disease}}, journal = {Archives of neurology}, year = {2012}, doi = {10.1001/archneurol.2011.3405}, pmid = {22409939}, url = {https://doi.org/10.1001/archneurol.2011.3405} } @article{mahley1988-3283935, author = {Mahley, Robert W.}, title = {{Apolipoprotein E: Cholesterol Transport Protein with Expanding Role in Cell Biology}}, journal = {Science}, year = {1988}, doi = {10.1126/science.3283935}, pmid = {3283935}, url = {https://doi.org/10.1126/science.3283935} } @article{desikan2017-28323831, author = {Desikan, R. S. and Fan, C. C. and Wang, Y. and Schork, A. J. and Cabral, H. J. and Cupples, L. A. and Thompson, W. K. and Besser, L. and others}, title = {{Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score}}, journal = {PLoS medicine}, year = {2017}, doi = {10.1371/journal.pmed.1002258}, pmid = {28323831}, url = {https://doi.org/10.1371/journal.pmed.1002258} } @article{wu2026-42427166, author = {Wu, Y. and Rojas-Saunero, L. P. and Zhou, Y. and Hayes-Larson, E. and Fong, J. O. and Mobley, T. and Brenowitz, W. D. and Hoffmann, T. J. and Deters, K. D. and Whitmer, R. A. and Gilsanz, P. and Gee, G. C. and others}, title = {{APOE-ε4 carriership and dementia risk over 10 years among Asian American and White older adults}}, journal = {Alzheimer's \& Dementia}, year = {2026}, doi = {10.1002/alz.71615}, pmid = {42427166}, url = {https://doi.org/10.1002/alz.71615} } @article{decarli2004-15277612, author = {DeCarli, C. and Mungas, D. and Harvey, D. and Reed, B. and Weiner, M. and Chui, H. and Jagust, W.}, title = {{Memory impairment, but not cerebrovascular disease, predicts progression of MCI to dementia}}, journal = {Neurology}, year = {2004}, doi = {10.1212/01.wnl.0000130531.90205.ef}, pmid = {15277612}, url = {https://doi.org/10.1212/01.wnl.0000130531.90205.ef} } @article{vemuri2010-20373342, author = {Vemuri, P. and Wiste, H. J. and Weigand, S. D. and Knopman, D. S. and Shaw, L. M. and Trojanowski, J. Q. and Aisen, P. S. and Weiner, M. and others}, title = {{Effect of apolipoprotein E on biomarkers of amyloid load and neuronal pathology in Alzheimer disease}}, journal = {Annals of neurology}, year = {2010}, doi = {10.1002/ana.21953}, pmid = {20373342}, url = {https://doi.org/10.1002/ana.21953} } @article{strittmatter1993-8367470, author = {Strittmatter, W. J. and Weisgraber, K. H. and Huang, D. Y. and Dong, L. M. and Salvesen, G. S. and Pericak-Vance, M. and Schmechel, D. and Saunders, A. M. and others}, title = {{Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease}}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, year = {1993}, doi = {10.1073/pnas.90.17.8098}, pmid = {8367470}, url = {https://doi.org/10.1073/pnas.90.17.8098} } @article{migliaccio2009-19901249, author = {Migliaccio, R. and Agosta, F. and Rascovsky, K. and Karydas, A. and Bonasera, S. and Rabinovici, G. D. and Miller, B. L. and Gorno-Tempini, M. L.}, title = {{Clinical syndromes associated with posterior atrophy: early age at onset AD spectrum}}, journal = {Neurology}, year = {2009}, doi = {10.1212/wnl.0b013e3181c0d427}, pmid = {19901249}, url = {https://doi.org/10.1212/wnl.0b013e3181c0d427} } @article{blumenfeld2024-38191720, author = {Blumenfeld, J. and Yip, O. and Kim, M. J. and Huang, Y.}, title = {{Cell type-specific roles of APOE4 in Alzheimer disease}}, journal = {Nature reviews. Neuroscience}, year = {2024}, doi = {10.1038/s41583-023-00776-9}, pmid = {38191720}, url = {https://doi.org/10.1038/s41583-023-00776-9} } @article{wingo2019-31135820, author = {Wingo, T. S. and Cutler, D. J. and Wingo, A. P. and Le, N. A. and Rabinovici, G. D. and Miller, B. L. and Lah, J. J. and Levey, A. I.}, title = {{Association of Early-Onset Alzheimer Disease With Elevated Low-Density Lipoprotein Cholesterol Levels and Rare Genetic Coding Variants of APOB}}, journal = {JAMA neurology}, year = {2019}, doi = {10.1001/jamaneurol.2019.0648}, pmid = {31135820}, url = {https://doi.org/10.1001/jamaneurol.2019.0648} } @article{mahley2016-27174096, author = {Mahley, R. W.}, title = {{Central Nervous System Lipoproteins: ApoE and Regulation of Cholesterol Metabolism}}, journal = {Arteriosclerosis, thrombosis, and vascular biology}, year = {2016}, doi = {10.1161/atvbaha.116.307023}, pmid = {27174096}, url = {https://doi.org/10.1161/atvbaha.116.307023} } @article{chatterjee2025-41235132, author = {Chatterjee, Aadrita and Cavaillès, Clémence and Davies, Neil M and Yaffe, Kristine S. and Andrews, Shea J.}, title = {{Disentangling the Causal Effects of Education and Participation Bias on Alzheimer Disease Using Mendelian Randomization}}, journal = {Neurology Genetics}, year = {2025}, doi = {10.1212/nxg.0000000000200307}, pmid = {41235132}, url = {https://doi.org/10.1212/nxg.0000000000200307} } @article{evans1995-7846048, author = {Evans, K. C. and Berger, E. P. and Cho, C. G. and Weisgraber, K. H. and Lansbury, P. T.}, title = {{Apolipoprotein E is a kinetic but not a thermodynamic inhibitor of amyloid formation: implications for the pathogenesis and treatment of Alzheimer disease}}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, year = {1995}, doi = {10.1073/pnas.92.3.763}, pmid = {7846048}, url = {https://doi.org/10.1073/pnas.92.3.763} } @article{chen2011-21118811, author = {Chen, H. K. and Ji, Z. S. and Dodson, S. E. and Miranda, R. D. and Rosenblum, C. I. and Reynolds, I. J. and Freedman, S. B. and Weisgraber, K. H. and others}, title = {{Apolipoprotein E4 domain interaction mediates detrimental effects on mitochondria and is a potential therapeutic target for Alzheimer disease}}, journal = {The Journal of biological chemistry}, year = {2011}, doi = {10.1074/jbc.m110.151084}, pmid = {21118811}, url = {https://doi.org/10.1074/jbc.m110.151084} } @article{buttini2002-12486146, author = {Buttini, M. and Yu, G. Q. and Shockley, K. and Huang, Y. and Jones, B. and Masliah, E. and Mallory, M. and Yeo, T. and others}, title = {{Modulation of Alzheimer-like synaptic and cholinergic deficits in transgenic mice by human apolipoprotein E depends on isoform, aging, and overexpression of amyloid beta peptides but not on plaque formation}}, journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience}, year = {2002}, doi = {10.1523/jneurosci.22-24-10539.2002}, pmid = {12486146}, url = {https://doi.org/10.1523/jneurosci.22-24-10539.2002} } @article{zhang2025-40715455, author = {Zhang, Sai Mei and Shu, Hantao and Zhou, Jingtian and Rubin-Sigler, Jasper and Yang, Xiaoyu Jenny and Liu, Yuxi and Cooper‐Knock, Johnathan and Monte, Emma and others}, title = {{Single-cell polygenic risk scores dissect cellular and molecular heterogeneity of complex human diseases}}, journal = {Nature Biotechnology}, year = {2025}, doi = {10.1038/s41587-025-02725-6}, pmid = {40715455}, url = {https://doi.org/10.1038/s41587-025-02725-6} } @article{karch2018-29630712, author = {Karch, C. M. and Wen, N. and Fan, C. C. and Yokoyama, J. S. and Kouri, N. and Ross, O. A. and Höglinger, G. and Müller, U. and others}, title = {{Selective Genetic Overlap Between Amyotrophic Lateral Sclerosis and Diseases of the Frontotemporal Dementia Spectrum}}, journal = {JAMA neurology}, year = {2018}, doi = {10.1001/jamaneurol.2018.0372}, pmid = {29630712}, url = {https://doi.org/10.1001/jamaneurol.2018.0372} } @article{krogsaeter2025-41103078, author = {Krogsaeter, Einar Kleinhans and McKetney, Justin and Valiente‐Banuet, Leopoldo and Marquez, Angelica and Willis, Alexandra R. and Cakir, Zeynep and Stevenson, Erica J. and Jang, Gwendolyn Μ. and others}, title = {{Lysosomal proteomics reveals mechanisms of neuronal APOE4-associated lysosomal dysfunction}}, journal = {Autophagy}, year = {2025}, doi = {10.1080/15548627.2025.2576613}, pmid = {41103078}, url = {https://doi.org/10.1080/15548627.2025.2576613} } @article{huang2006-16432152, author = {Huang, Y.}, title = {{Apolipoprotein E and Alzheimer disease}}, journal = {Neurology}, year = {2006}, doi = {10.1212/01.wnl.0000192102.41141.9e}, pmid = {16432152}, url = {https://doi.org/10.1212/01.wnl.0000192102.41141.9e} } @article{nassan2025-40103583, author = {Nassan, Malik M. and Daghlas, Iyas and Diamond, Bram R and Martersteck, Adam and Rogalski, Emily Joy}, title = {{The causal association between resting state intrinsic functional networks and neurodegeneration}}, journal = {Brain Communications}, year = {2025}, doi = {10.1093/braincomms/fcaf098}, pmid = {40103583}, url = {https://doi.org/10.1093/braincomms/fcaf098} } @article{hatters2005-16076841, author = {Hatters, D. M. and Budamagunta, M. S. and Voss, J. C. and Weisgraber, K. H.}, title = {{Modulation of apolipoprotein E structure by domain interaction: differences in lipid-bound and lipid-free forms}}, journal = {The Journal of biological chemistry}, year = {2005}, doi = {10.1074/jbc.m506044200}, pmid = {16076841}, url = {https://doi.org/10.1074/jbc.m506044200} } @article{graff2025-41128446, author = {Graff, Rebecca E. and Chen, Dorothy M. and Swinnerton, Kaitlin N. and Ackley, Sarah F. and Ospina‐Romero, Monica and Zimmerman, Scott C. and Wang, Jingxuan and Buto, Peter T. and others}, title = {{Evaluation of Polygenic Risk Scores for a Possible Genetic Basis of the Inverse Association Between Cancer and Cognitive Decline}}, journal = {Alzheimer Disease \& Associated Disorders}, year = {2025}, doi = {10.1097/wad.0000000000000696}, pmid = {41128446}, url = {https://doi.org/10.1097/wad.0000000000000696} } @article{jiang2025-41434402, author = {Jiang, Xiaqing and O’Bryant, Sid E. and Rissman, Robert A. and Johnson, Leigh A and Braskie, Meredith N. and Yaffe, Kristine S.}, title = {{Multimorbidity, Cognition, and Alzheimer Disease Biomarkers: A Pathway Analysis}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz70862_110144}, pmid = {41434402}, url = {https://doi.org/10.1002/alz70862_110144} }