% alzhub.org library filter % Source: https://alzhub.org/research?category=drug_development&year=2016 % 22 entries, in the order the page lists them. Built from alzhub.org's own records. % 0 entries have no readable author in the source record and carry no author field. @article{gauthier2016-27863809, author = {Gauthier, S. and Feldman, H. H. and Schneider, L. S. and Wilcock, G. K. and Frisoni, G. B. and Hardlund, J. H. and Moebius, H. J. and others}, title = {{Efficacy and safety of tau-aggregation inhibitor therapy in patients with mild or moderate Alzheimer's disease: a randomised, controlled, double-blind, parallel-arm, phase 3 trial}}, journal = {Lancet (London, England)}, year = {2016}, doi = {10.1016/s0140-6736(16)31275-2}, pmid = {27863809}, url = {https://doi.org/10.1016/s0140-6736(16)31275-2} } @article{luchsinger2016-26890736, author = {Luchsinger, J. A. and Perez, T. and Chang, H. and Mehta, P. and Steffener, J. and Pradabhan, G. and Ichise, M. and Manly, J. and others}, title = {{Metformin in Amnestic Mild Cognitive Impairment: Results of a Pilot Randomized Placebo Controlled Clinical Trial}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2016}, doi = {10.3233/jad-150493}, pmid = {26890736}, url = {https://doi.org/10.3233/jad-150493} } @article{islam2016-28013304, author = {Islam, M. M. and Iqbal, U. and Walther, B. and Atique, S. and Dubey, N. K. and Nguyen, P. A. and Poly, T. N. and Masud, J. H. and others}, title = {{Benzodiazepine Use and Risk of Dementia in the Elderly Population: A Systematic Review and Meta-Analysis}}, journal = {Neuroepidemiology}, year = {2016}, doi = {10.1159/000454881}, pmid = {28013304}, url = {https://doi.org/10.1159/000454881} } @article{saito2016-29067312, author = {Saito, Satoshi and Kojima, Shinsuke and Oishi, Naoya and Kakuta, Ryosuke and Maki, Takakuni and Yasuno, Fumihiko and Nagatsuka, Kazuyuki and Yamamoto, Haruko and others}, title = {{A multicenter, randomized, placebo-controlled trial for cilostazol in patients with mild cognitive impairment: The COMCID study protocol}}, journal = {Alzheimer's \& dementia (New York, N. Y.)}, year = {2016}, doi = {10.1016/j.trci.2016.10.001}, pmid = {29067312}, url = {https://doi.org/10.1016/j.trci.2016.10.001} } @article{gejl2016-27252647, author = {Gejl, M. and Gjedde, A. and Egefjord, L. and Møller, A. and Hansen, S. B. and Vang, K. and Rodell, A. and Brændgaard, H. and others}, title = {{In Alzheimer's Disease, 6-Month Treatment with GLP-1 Analog Prevents Decline of Brain Glucose Metabolism: Randomized, Placebo-Controlled, Double-Blind Clinical Trial}}, journal = {Frontiers in aging neuroscience}, year = {2016}, doi = {10.3389/fnagi.2016.00108}, pmid = {27252647}, url = {https://doi.org/10.3389/fnagi.2016.00108} } @article{panza2016-27429978, author = {Panza, F. and Solfrizzi, V. and Seripa, D. and Imbimbo, B. P. and Lozupone, M. and Santamato, A. and Zecca, C. and Barulli, M. R. and others}, title = {{Tau-Centric Targets and Drugs in Clinical Development for the Treatment of Alzheimer's Disease}}, journal = {BioMed research international}, year = {2016}, doi = {10.1155/2016/3245935}, pmid = {27429978}, url = {https://doi.org/10.1155/2016/3245935} } @article{daniels2016-27509875, author = {Daniels, M. J. and Rivers-Auty, J. and Schilling, T. and Spencer, N. G. and Watremez, W. and Fasolino, V. and Booth, S. J. and White, C. S. and others}, title = {{Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer's disease in rodent models}}, journal = {Nature communications}, year = {2016}, doi = {10.1038/ncomms12504}, pmid = {27509875}, url = {https://doi.org/10.1038/ncomms12504} } @article{malia2016-26800003, author = {Malia, T. J. and Teplyakov, A. and Ernst, R. and Wu, S. J. and Lacy, E. R. and Liu, X. and Vandermeeren, M. and Mercken, M. and others}, title = {{Epitope mapping and structural basis for the recognition of phosphorylated tau by the anti-tau antibody AT8}}, journal = {Proteins}, year = {2016}, doi = {10.1002/prot.24988}, pmid = {26800003}, url = {https://doi.org/10.1002/prot.24988} } @article{hinrich2016-26902204, author = {Hinrich, A. J. and Jodelka, F. M. and Chang, J. L. and Brutman, D. and Bruno, A. M. and Briggs, C. A. and James, B. D. and Stutzmann, G. E. and others}, title = {{Therapeutic correction of ApoER2 splicing in Alzheimer's disease mice using antisense oligonucleotides}}, journal = {EMBO molecular medicine}, year = {2016}, doi = {10.15252/emmm.201505846}, pmid = {26902204}, url = {https://doi.org/10.15252/emmm.201505846} } @article{hughes2016-27199640, author = {Hughes, R. E. and Nikolic, K. and Ramsay, R. R.}, title = {{One for All? Hitting Multiple Alzheimer's Disease Targets with One Drug}}, journal = {Frontiers in neuroscience}, year = {2016}, doi = {10.3389/fnins.2016.00177}, pmid = {27199640}, url = {https://doi.org/10.3389/fnins.2016.00177} } @article{hansen2016-27421117, author = {Hansen, Henrik H. and Fabricius, Katrine and Barkholt, Pernille and Wismann, Pernille and Schlumberger, Chantal and Jelsing, Jacob and Terwel, Dick and Termont, Annelies and others}, title = {{Long-Term Treatment with Liraglutide, a Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist, Has No Effect on β-Amyloid Plaque Load in Two Transgenic APP/PS1 Mouse Models of Alzheimer’s Disease}}, journal = {PLoS ONE}, year = {2016}, doi = {10.1371/journal.pone.0158205}, pmid = {27421117}, url = {https://doi.org/10.1371/journal.pone.0158205} } @article{muscogiuri2017-27871675, author = {Muscogiuri, G. and DeFronzo, R. A. and Gastaldelli, A. and Holst, J. J.}, title = {{Glucagon-like Peptide-1 and the Central/Peripheral Nervous System: Crosstalk in Diabetes}}, journal = {Trends in endocrinology and metabolism: TEM}, year = {2017}, doi = {10.1016/j.tem.2016.10.001}, pmid = {27871675}, url = {https://doi.org/10.1016/j.tem.2016.10.001} } @article{kosaraju2017-27699599, author = {Kosaraju, J. and Holsinger, R. M. D. and Guo, L. and Tam, K. Y.}, title = {{Linagliptin, a Dipeptidyl Peptidase-4 Inhibitor, Mitigates Cognitive Deficits and Pathology in the 3xTg-AD Mouse Model of Alzheimer's Disease}}, journal = {Molecular neurobiology}, year = {2017}, doi = {10.1007/s12035-016-0125-7}, pmid = {27699599}, url = {https://doi.org/10.1007/s12035-016-0125-7} } @article{dey2017-28043897, author = {Dey, A. and Bhattacharya, R. and Mukherjee, A. and Pandey, D. K.}, title = {{Natural products against Alzheimer's disease: Pharmaco-therapeutics and biotechnological interventions}}, journal = {Biotechnology advances}, year = {2017}, doi = {10.1016/j.biotechadv.2016.12.005}, pmid = {28043897}, url = {https://doi.org/10.1016/j.biotechadv.2016.12.005} } @article{seripa2016-26822031, author = {Seripa, Davide and Solfrizzi, Vincenzo and Imbimbo, Bruno P and Daniele, Antonio and Santamato, Andrea and Lozupone, Madia and Zuliani, Giovanni and Greco, Antonio and others}, title = {{Tau-directed approaches for the treatment of Alzheimer's disease: focus on leuco-methylthioninium}}, journal = {Expert review of neurotherapeutics}, year = {2016}, doi = {10.1586/14737175.2016.1140039}, pmid = {26822031}, url = {https://doi.org/10.1586/14737175.2016.1140039} } @article{zhang2016-28005991, author = {Zhang, Ming and Schmitt-Ulms, Gerold and Sato, Christine and Xi, Zhengrui and Zhang, Yalun and Zhou, Ye and George-Hyslop, Peter St and Rogaeva, Ekaterina}, title = {{Drug Repositioning for Alzheimer's Disease Based on Systematic 'omics' Data Mining}}, journal = {PloS one}, year = {2016}, doi = {10.1371/journal.pone.0168812}, pmid = {28005991}, url = {https://doi.org/10.1371/journal.pone.0168812} } @article{son2016-26967226, author = {Son, Sung Min and Shin, Hong-Joon and Byun, Jayoung and Kook, Sun Young and Moon, Minho and Chang, Yu Jin and Mook-Jung, Inhee}, title = {{Metformin Facilitates Amyloid-β Generation by β- and γ-Secretases via Autophagy Activation}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2016}, doi = {10.3233/jad-151200}, pmid = {26967226}, url = {https://doi.org/10.3233/jad-151200} } @article{lee2016-27475227, author = {Lee, S. H. and Le Pichon, C. E. and Adolfsson, O. and Gafner, V. and Pihlgren, M. and Lin, H. and Solanoy, H. and Brendza, R. and others}, title = {{Antibody-Mediated Targeting of Tau In Vivo Does Not Require Effector Function and Microglial Engagement}}, journal = {Cell reports}, year = {2016}, doi = {10.1016/j.celrep.2016.06.099}, pmid = {27475227}, url = {https://doi.org/10.1016/j.celrep.2016.06.099} } @article{athauda2016-26851597, author = {Athauda, D. and Foltynie, T.}, title = {{The glucagon-like peptide 1 (GLP) receptor as a therapeutic target in Parkinson's disease: mechanisms of action}}, journal = {Drug discovery today}, year = {2016}, doi = {10.1016/j.drudis.2016.01.013}, pmid = {26851597}, url = {https://doi.org/10.1016/j.drudis.2016.01.013} } @article{qi2016-27131827, author = {Qi, L. and Ke, L. and Liu, X. and Liao, L. and Ke, S. and Wang, Y. and Lin, X. and others}, title = {{Subcutaneous administration of liraglutide ameliorates learning and memory impairment by modulating tau hyperphosphorylation via the glycogen synthase kinase-3β pathway in an amyloid β protein induced alzheimer disease mouse model}}, journal = {European journal of pharmacology}, year = {2016}, doi = {10.1016/j.ejphar.2016.04.052}, pmid = {27131827}, url = {https://doi.org/10.1016/j.ejphar.2016.04.052} } @article{ji2016-26351802, author = {Ji, C. and Xue, G. F. and Li, G. and Li, D. and Hölscher, C.}, title = {{Neuroprotective effects of glucose-dependent insulinotropic polypeptide in Alzheimer's disease}}, journal = {Reviews in the neurosciences}, year = {2016}, doi = {10.1515/revneuro-2015-0021}, pmid = {26351802}, url = {https://doi.org/10.1515/revneuro-2015-0021} } @article{beckmann2016-27459925, author = {Beckmann, N. and Doelemeyer, A. and Zurbruegg, S. and Bigot, K. and Theil, D. and Frieauff, W. and Kolly, C. and Moulin, P. and others}, title = {{Longitudinal noninvasive magnetic resonance imaging of brain microhemorrhages in BACE inhibitor-treated APP transgenic mice}}, journal = {Neurobiology of aging}, year = {2016}, doi = {10.1016/j.neurobiolaging.2016.05.009}, pmid = {27459925}, url = {https://doi.org/10.1016/j.neurobiolaging.2016.05.009} }