% alzhub.org library filter
% Source: https://alzhub.org/research?category=drug_development&year=2015
% 35 entries, in the order the page lists them. Built from alzhub.org's own records.
% 0 entries have no readable author in the source record and carry no author field.

@article{ott2015-25575908,
  author  = {Ott, B. R. and Daiello, L. A. and Dahabreh, I. J. and Springate, B. A. and Bixby, K. and Murali, M. and Trikalinos, T. A.},
  title   = {{Do statins impair cognition? A systematic review and meta-analysis of randomized controlled trials}},
  journal = {Journal of general internal medicine},
  year    = {2015},
  doi     = {10.1007/s11606-014-3115-3},
  pmid    = {25575908},
  url     = {https://doi.org/10.1007/s11606-014-3115-3}
}

@article{xu2015-26294005,
  author  = {Xu, W. and Tan, L. and Wang, H. F. and Jiang, T. and Tan, M. S. and Zhao, Q. F. and Li, J. Q. and others},
  title   = {{Meta-analysis of modifiable risk factors for Alzheimer's disease}},
  journal = {Journal of neurology, neurosurgery, and psychiatry},
  year    = {2015},
  doi     = {10.1136/jnnp-2015-310548},
  pmid    = {26294005},
  url     = {https://doi.org/10.1136/jnnp-2015-310548}
}

@article{haroon2015-26258401,
  author  = {Haroon, N. N. and Paterson, J. M. and Li, P. and Inman, R. D. and Haroon, N.},
  title   = {{Patients With Ankylosing Spondylitis Have Increased Cardiovascular and Cerebrovascular Mortality: A Population-Based Study}},
  journal = {Annals of internal medicine},
  year    = {2015},
  doi     = {10.7326/m14-2470},
  pmid    = {26258401},
  url     = {https://doi.org/10.7326/m14-2470}
}

@article{ostergaard2015-26079503,
  author  = {Østergaard, S. D. and Mukherjee, S. and Sharp, S. J. and Proitsi, P. and Lotta, L. A. and Day, F. and Perry, JR. and Boehme, K. L. and others},
  title   = {{Associations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study}},
  journal = {PLoS medicine},
  year    = {2015},
  doi     = {10.1371/journal.pmed.1001841},
  pmid    = {26079503},
  url     = {https://doi.org/10.1371/journal.pmed.1001841}
}

@article{sridhar2015-26069723,
  author  = {Sridhar, G. R. and Lakshmi, G. and Nagamani, G.},
  title   = {{Emerging links between type 2 diabetes and Alzheimer's disease}},
  journal = {World journal of diabetes},
  year    = {2015},
  doi     = {10.4239/wjd.v6.i5.744},
  pmid    = {26069723},
  url     = {https://doi.org/10.4239/wjd.v6.i5.744}
}

@article{zhang2015-25946000,
  author  = {Zhang, Ming and Luo, Heng and Xi, Zhengrui and Rogaeva, Ekaterina},
  title   = {{Drug repositioning for diabetes based on 'omics' data mining}},
  journal = {PloS one},
  year    = {2015},
  doi     = {10.1371/journal.pone.0126082},
  pmid    = {25946000},
  url     = {https://doi.org/10.1371/journal.pone.0126082}
}

@article{zack2015-2d3045db,
  author  = {Zack, Julia and Berg, Jolene and Juan, Axel and Pannacciulli, Nicola and Allard, Martine and Gottwald, Mildred and Zhang, Heather and Shao, Yongwu and others},
  title   = {{Pharmacokinetic drug–drug interaction study of ranolazine and metformin in subjects with type 2 diabetes mellitus}},
  journal = {Clinical Pharmacology in Drug Development},
  year    = {2015},
  doi     = {10.1002/cpdd.174},
  url     = {https://doi.org/10.1002/cpdd.174}
}

@article{hansen2016-26746341,
  author  = {Hansen, H. H. and Barkholt, P. and Fabricius, K. and Jelsing, J. and Terwel, D. and Pyke, C. and Knudsen, L. B. and Vrang, N.},
  title   = {{The GLP-1 receptor agonist liraglutide reduces pathology-specific tau phosphorylation and improves motor function in a transgenic hTauP301L mouse model of tauopathy}},
  journal = {Brain research},
  year    = {2016},
  doi     = {10.1016/j.brainres.2015.12.052},
  pmid    = {26746341},
  url     = {https://doi.org/10.1016/j.brainres.2015.12.052}
}

@article{luo2015-26057852,
  author  = {Luo, W. and Liu, W. and Hu, X. and Hanna, M. and Caravaca, A. and Paul, S. M.},
  title   = {{Microglial internalization and degradation of pathological tau is enhanced by an anti-tau monoclonal antibody}},
  journal = {Scientific reports},
  year    = {2015},
  doi     = {10.1038/srep11161},
  pmid    = {26057852},
  url     = {https://doi.org/10.1038/srep11161}
}

@article{sankaranarayanan2015-25933020,
  author  = {Sankaranarayanan, S. and Barten, D. M. and Vana, L. and Devidze, N. and Yang, L. and Cadelina, G. and Hoque, N. and DeCarr, L. and others},
  title   = {{Passive immunization with phospho-tau antibodies reduces tau pathology and functional deficits in two distinct mouse tauopathy models}},
  journal = {PloS one},
  year    = {2015},
  doi     = {10.1371/journal.pone.0125614},
  pmid    = {25933020},
  url     = {https://doi.org/10.1371/journal.pone.0125614}
}

@article{hochgrafe2015-25958115,
  author  = {Hochgräfe, K. and Sydow, A. and Matenia, D. and Cadinu, D. and Könen, S. and Petrova, O. and Pickhardt, M. and Goll, P. and others},
  title   = {{Preventive methylene blue treatment preserves cognition in mice expressing full-length pro-aggregant human Tau}},
  journal = {Acta neuropathologica communications},
  year    = {2015},
  doi     = {10.1186/s40478-015-0204-4},
  pmid    = {25958115},
  url     = {https://doi.org/10.1186/s40478-015-0204-4}
}

@article{li2015-25792818,
  author  = {Li, X. and Song, D. and Leng, S. X.},
  title   = {{Link between type 2 diabetes and Alzheimer's disease: from epidemiology to mechanism and treatment}},
  journal = {Clinical interventions in aging},
  year    = {2015},
  doi     = {10.2147/cia.s74042},
  pmid    = {25792818},
  url     = {https://doi.org/10.2147/cia.s74042}
}

@article{hansen2015-25869785,
  author  = {Hansen, H. H. and Fabricius, K. and Barkholt, P. and Niehoff, M. L. and Morley, J. E. and Jelsing, J. and Pyke, C. and Knudsen, L. B. and others},
  title   = {{The GLP-1 Receptor Agonist Liraglutide Improves Memory Function and Increases Hippocampal CA1 Neuronal Numbers in a Senescence-Accelerated Mouse Model of Alzheimer's Disease}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2015},
  doi     = {10.3233/jad-143090},
  pmid    = {25869785},
  url     = {https://doi.org/10.3233/jad-143090}
}

@article{yamagishi2015-25582643,
  author  = {Yamagishi, S. and Fukami, K. and Matsui, T.},
  title   = {{Crosstalk between advanced glycation end products (AGEs)-receptor RAGE axis and dipeptidyl peptidase-4-incretin system in diabetic vascular complications}},
  journal = {Cardiovascular diabetology},
  year    = {2015},
  doi     = {10.1186/s12933-015-0176-5},
  pmid    = {25582643},
  url     = {https://doi.org/10.1186/s12933-015-0176-5}
}

@article{solmaz2015-26386291,
  author  = {Solmaz, V. and Çınar, B. P. and Yiğittürk, G. and Çavuşoğlu, T. and Taşkıran, D. and Erbaş, O.},
  title   = {{Exenatide reduces TNF-α expression and improves hippocampal neuron numbers and memory in streptozotocin treated rats}},
  journal = {European journal of pharmacology},
  year    = {2015},
  doi     = {10.1016/j.ejphar.2015.09.024},
  pmid    = {26386291},
  url     = {https://doi.org/10.1016/j.ejphar.2015.09.024}
}

@article{xu2015-25479064,
  author  = {Xu, W. and Yang, Y. and Yuan, G. and Zhu, W. and Ma, D. and Hu, S.},
  title   = {{Exendin-4, a glucagon-like peptide-1 receptor agonist, reduces Alzheimer disease-associated tau hyperphosphorylation in the hippocampus of rats with type 2 diabetes}},
  journal = {Journal of investigative medicine : the official publication of the American Federation for Clinical Research},
  year    = {2015},
  doi     = {10.1097/jim.0000000000000129},
  pmid    = {25479064},
  url     = {https://doi.org/10.1097/jim.0000000000000129}
}

@article{ma2015-26183127,
  author  = {Ma, D. L. and Chen, F. Q. and Xu, W. J. and Yue, W. Z. and Yuan, G. and Yang, Y.},
  title   = {{Early intervention with glucagon-like peptide 1 analog liraglutide prevents tau hyperphosphorylation in diabetic db/db mice}},
  journal = {Journal of neurochemistry},
  year    = {2015},
  doi     = {10.1111/jnc.13248},
  pmid    = {26183127},
  url     = {https://doi.org/10.1111/jnc.13248}
}

@article{sigurdsson2016-26551002,
  author  = {Sigurdsson, Einar M},
  title   = {{Tau Immunotherapy}},
  journal = {Neuro-degenerative diseases},
  year    = {2016},
  doi     = {10.1159/000440842},
  pmid    = {26551002},
  url     = {https://doi.org/10.1159/000440842}
}

@article{yang2016-26640240,
  author  = {Yang, Yan and Ma, Delin and Xu, Weijie and Chen, Fuqiong and Du, Tingting and Yue, Wenzhu and Shao, Shiying and Yuan, Gang},
  title   = {{Exendin-4 reduces tau hyperphosphorylation in type 2 diabetic rats via increasing brain insulin level}},
  journal = {Molecular and cellular neurosciences},
  year    = {2016},
  doi     = {10.1016/j.mcn.2015.10.005},
  pmid    = {26640240},
  url     = {https://doi.org/10.1016/j.mcn.2015.10.005}
}

@article{siavelis2016-26197808,
  author  = {Siavelis, John C and Bourdakou, Marilena M and Athanasiadis, Emmanouil I and Spyrou, George M and Nikita, Konstantina S},
  title   = {{Bioinformatics methods in drug repurposing for Alzheimer's disease}},
  journal = {Briefings in bioinformatics},
  year    = {2016},
  doi     = {10.1093/bib/bbv048},
  pmid    = {26197808},
  url     = {https://doi.org/10.1093/bib/bbv048}
}

@article{corbett2015-25961694,
  author  = {Corbett, Anne and Williams, Gareth and Ballard, Clive},
  title   = {{Drug repositioning in Alzheimer's disease}},
  journal = {Frontiers in bioscience (Scholar edition)},
  year    = {2015},
  doi     = {10.2741/s432},
  pmid    = {25961694},
  url     = {https://doi.org/10.2741/s432}
}

@article{pedersen2015-25846560,
  author  = {Pedersen, J. T. and Sigurdsson, E. M.},
  title   = {{Tau immunotherapy for Alzheimer's disease}},
  journal = {Trends in molecular medicine},
  year    = {2015},
  doi     = {10.1016/j.molmed.2015.03.003},
  pmid    = {25846560},
  url     = {https://doi.org/10.1016/j.molmed.2015.03.003}
}

@article{sengupta2015-25676491,
  author  = {Sengupta, U. and Guerrero-Muñoz, M. J. and Castillo-Carranza, D. L. and Lasagna-Reeves, C. A. and Gerson, J. E. and Paulucci-Holthauzen, A. A. and Krishnamurthy, S. and Farhed, M. and others},
  title   = {{Pathological interface between oligomeric alpha-synuclein and tau in synucleinopathies}},
  journal = {Biological psychiatry},
  year    = {2015},
  doi     = {10.1016/j.biopsych.2014.12.019},
  pmid    = {25676491},
  url     = {https://doi.org/10.1016/j.biopsych.2014.12.019}
}

@article{stratmann2016-26193084,
  author  = {Stratmann, K. and Heinsen, H. and Korf, H. W. and Del Turco, D. and Ghebremedhin, E. and Seidel, K. and Bouzrou, M. and Grinberg, L. T. and others},
  title   = {{Precortical Phase of Alzheimer's Disease (AD)-Related Tau Cytoskeletal Pathology}},
  journal = {Brain pathology (Zurich, Switzerland)},
  year    = {2016},
  doi     = {10.1111/bpa.12289},
  pmid    = {26193084},
  url     = {https://doi.org/10.1111/bpa.12289}
}

@article{castillocarranza2015-25810517,
  author  = {Castillo-Carranza, D. L. and Guerrero-Muñoz, M. J. and Sengupta, U. and Hernandez, C. and Barrett, A. D. and Dineley, K. and Kayed, R.},
  title   = {{Tau immunotherapy modulates both pathological tau and upstream amyloid pathology in an Alzheimer's disease mouse model}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2015},
  doi     = {10.1523/jneurosci.4989-14.2015},
  pmid    = {25810517},
  url     = {https://doi.org/10.1523/jneurosci.4989-14.2015}
}

@article{kim2015-26538644,
  author  = {Kim, J. and Yoon, H. and Horie, T. and Burchett, J. M. and Restivo, J. L. and Rotllan, N. and Ramírez, C. M. and Verghese, P. B. and others},
  title   = {{microRNA-33 Regulates ApoE Lipidation and Amyloid-β Metabolism in the Brain}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2015},
  doi     = {10.1523/jneurosci.2053-15.2015},
  pmid    = {26538644},
  url     = {https://doi.org/10.1523/jneurosci.2053-15.2015}
}

@article{funk2015-26126828,
  author  = {Funk, K. E. and Mirbaha, H. and Jiang, H. and Holtzman, D. M. and Diamond, M. I.},
  title   = {{Distinct Therapeutic Mechanisms of Tau Antibodies: Promoting Microglial Clearance Versus Blocking Neuronal Uptake}},
  journal = {The Journal of biological chemistry},
  year    = {2015},
  doi     = {10.1074/jbc.m115.657924},
  pmid    = {26126828},
  url     = {https://doi.org/10.1074/jbc.m115.657924}
}

@article{xia2015-25558816,
  author  = {Xia, D. and Li, C. and Götz, J.},
  title   = {{Pseudophosphorylation of Tau at distinct epitopes or the presence of the P301L mutation targets the microtubule-associated protein Tau to dendritic spines}},
  journal = {Biochimica et biophysica acta},
  year    = {2015},
  doi     = {10.1016/j.bbadis.2014.12.017},
  pmid    = {25558816},
  url     = {https://doi.org/10.1016/j.bbadis.2014.12.017}
}

@article{liu2015-26141845,
  author  = {Liu, W. and Jalewa, J. and Sharma, M. and Li, G. and Li, L. and Hölscher, C.},
  title   = {{Neuroprotective effects of lixisenatide and liraglutide in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease}},
  journal = {Neuroscience},
  year    = {2015},
  doi     = {10.1016/j.neuroscience.2015.06.054},
  pmid    = {26141845},
  url     = {https://doi.org/10.1016/j.neuroscience.2015.06.054}
}

@article{mcclean2015-26205827,
  author  = {McClean, P. L. and Jalewa, J. and Hölscher, C.},
  title   = {{Prophylactic liraglutide treatment prevents amyloid plaque deposition, chronic inflammation and memory impairment in APP/PS1 mice}},
  journal = {Behavioural brain research},
  year    = {2015},
  doi     = {10.1016/j.bbr.2015.07.024},
  pmid    = {26205827},
  url     = {https://doi.org/10.1016/j.bbr.2015.07.024}
}

@article{nassar2015-25446674,
  author  = {Nassar, N. N. and Al-Shorbagy, M. Y. and Arab, H. H. and Abdallah, D. M.},
  title   = {{Saxagliptin: a novel antiparkinsonian approach}},
  journal = {Neuropharmacology},
  year    = {2015},
  doi     = {10.1016/j.neuropharm.2014.10.007},
  pmid    = {25446674},
  url     = {https://doi.org/10.1016/j.neuropharm.2014.10.007}
}

@article{ji2016-26453833,
  author  = {Ji, C. and Xue, G. F. and Lijun, C. and Feng, P. and Li, D. and Li, L. and Li, G. and Hölscher, C.},
  title   = {{A novel dual GLP-1 and GIP receptor agonist is neuroprotective in the MPTP mouse model of Parkinson's disease by increasing expression of BNDF}},
  journal = {Brain research},
  year    = {2016},
  doi     = {10.1016/j.brainres.2015.09.035},
  pmid    = {26453833},
  url     = {https://doi.org/10.1016/j.brainres.2015.09.035}
}

@article{calsolaro2015-26666230,
  author  = {Calsolaro, V. and Edison, P.},
  title   = {{Novel GLP-1 (Glucagon-Like Peptide-1) Analogues and Insulin in the Treatment for Alzheimer's Disease and Other Neurodegenerative Diseases}},
  journal = {CNS drugs},
  year    = {2015},
  doi     = {10.1007/s40263-015-0301-8},
  pmid    = {26666230},
  url     = {https://doi.org/10.1007/s40263-015-0301-8}
}

@article{candeias2015-26131323,
  author  = {Candeias, E. M. and Sebastião, I. C. and Cardoso, S. M. and Correia, S. C. and Carvalho, C. I. and Plácido, A. I. and Santos, M. S. and Oliveira, C. R. and others},
  title   = {{Gut-brain connection: The neuroprotective effects of the anti-diabetic drug liraglutide}},
  journal = {World journal of diabetes},
  year    = {2015},
  doi     = {10.4239/wjd.v6.i6.807},
  pmid    = {26131323},
  url     = {https://doi.org/10.4239/wjd.v6.i6.807}
}

@article{roy2015-26118928,
  author  = {Roy, A. and Jana, M. and Kundu, M. and Corbett, G. T. and Rangaswamy, S. B. and Mishra, R. K. and Luan, C. H. and Gonzalez, F. J. and others},
  title   = {{HMG-CoA Reductase Inhibitors Bind to PPARα to Upregulate Neurotrophin Expression in the Brain and Improve Memory in Mice}},
  journal = {Cell metabolism},
  year    = {2015},
  doi     = {10.1016/j.cmet.2015.05.022},
  pmid    = {26118928},
  url     = {https://doi.org/10.1016/j.cmet.2015.05.022}
}