% alzhub.org library filter % Source: https://alzhub.org/research?category=drug_development&design=trial % 32 entries, in the order the page lists them. Built from alzhub.org's own records. % 0 entries have no readable author in the source record and carry no author field. @article{abdelhaleem2026-40435316, author = {Abdel-Haleem, Alyaa M and Casavant, Ellen and Toth, Balazs and Teng, Edmond and Monteiro, Cecilia and Pandya, Nikhil J and Glock, Caspar and Hoogenraad, Casper C and others}, title = {{CSF proteomics of semorinemab Alzheimer's disease trials identifies cell-type specific signatures}}, journal = {Brain : a journal of neurology}, year = {2026}, doi = {10.1093/brain/awaf200}, pmid = {40435316}, url = {https://doi.org/10.1093/brain/awaf200} } @article{jeong2022-36038268, author = {Jeong, S. Y. and Suh, C. H. and Shim, W. H. and Lim, J. S. and Lee, J. H. and Kim, S. J.}, title = {{Incidence of Amyloid-Related Imaging Abnormalities in Patients With Alzheimer Disease Treated With Anti-β-Amyloid Immunotherapy: A Meta-analysis}}, journal = {Neurology}, year = {2022}, doi = {10.1212/wnl.0000000000201019}, pmid = {36038268}, url = {https://doi.org/10.1212/wnl.0000000000201019} } @article{schauer2024-39513754, author = {Schauer, Stephen P and Toth, Balazs and Lee, Julie and Honigberg, Lee A and Ramakrishnan, Vidya and Jiang, Jenny and Kollmorgen, Gwendlyn and Bayfield, Anna and others}, title = {{Pharmacodynamic effects of semorinemab on plasma and CSF biomarkers of Alzheimer's disease pathophysiology}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2024}, doi = {10.1002/alz.14346}, pmid = {39513754}, url = {https://doi.org/10.1002/alz.14346} } @article{baddeley2015-25320049, author = {Baddeley, T. C. and McCaffrey, J. and Storey, J. M. and Cheung, J. K. and Melis, V. and Horsley, D. and Harrington, C. R. and Wischik, C. M.}, title = {{Complex disposition of methylthioninium redox forms determines efficacy in tau aggregation inhibitor therapy for Alzheimer's disease}}, journal = {The Journal of pharmacology and experimental therapeutics}, year = {2015}, doi = {10.1124/jpet.114.219352}, pmid = {25320049}, url = {https://doi.org/10.1124/jpet.114.219352} } @article{loomis2024-38165296, author = {Loomis, S. J. and Miller, R. and Castrillo-Viguera, C. and Umans, K. and Cheng, W. and O'Gorman, J. and Hughes, R. and Budd Haeberlein, S. and others}, title = {{Genome-Wide Association Studies of ARIA From the Aducanumab Phase 3 ENGAGE and EMERGE Studies}}, journal = {Neurology}, year = {2024}, doi = {10.1212/wnl.0000000000207919}, pmid = {38165296}, url = {https://doi.org/10.1212/wnl.0000000000207919} } @article{cummings2022-35516416, author = {Cummings, J. and Lee, G. and Nahed, P. and Kambar, M. E. Z. N. and Zhong, K. and Fonseca, J. and Taghva, K.}, title = {{Alzheimer's disease drug development pipeline: 2022}}, journal = {Alzheimer's \& dementia (New York, N. Y.)}, year = {2022}, doi = {10.1002/trc2.12295}, pmid = {35516416}, url = {https://doi.org/10.1002/trc2.12295} } @article{cummings2024-38659717, author = {Cummings, J. and Zhou, Y. and Lee, G. and Zhong, K. and Fonseca, J. and Cheng, F.}, title = {{Alzheimer's disease drug development pipeline: 2024}}, journal = {Alzheimer's \& dementia (New York, N. Y.)}, year = {2024}, doi = {10.1002/trc2.12465}, pmid = {38659717}, url = {https://doi.org/10.1002/trc2.12465} } @article{ramakrishnan2024-39350369, author = {Ramakrishnan, V and Bender, B and Langenhorst, J and Magnusson, M O and Dolton, M and Shim, J and Fuji, R N and Monteiro, C and others}, title = {{Semorinemab Pharmacokinetics and The Effect on Plasma Total Tau Pharmacodynamics in Clinical Studies}}, journal = {The journal of prevention of Alzheimer's disease}, year = {2024}, doi = {10.14283/jpad.2024.146}, pmid = {39350369}, url = {https://doi.org/10.14283/jpad.2024.146} } @article{cummings2021-34095440, author = {Cummings, J. and Lee, G. and Zhong, K. and Fonseca, J. and Taghva, K.}, title = {{Alzheimer's disease drug development pipeline: 2021}}, journal = {Alzheimer's \& dementia (New York, N. Y.)}, year = {2021}, doi = {10.1002/trc2.12179}, pmid = {34095440}, url = {https://doi.org/10.1002/trc2.12179} } @article{vitek2023-36749830, author = {Vitek, G. E. and Decourt, B. and Sabbagh, M. N.}, title = {{Lecanemab (BAN2401): an anti-beta-amyloid monoclonal antibody for the treatment of Alzheimer disease}}, journal = {Expert opinion on investigational drugs}, year = {2023}, doi = {10.1080/13543784.2023.2178414}, pmid = {36749830}, url = {https://doi.org/10.1080/13543784.2023.2178414} } @article{west2017-29181488, author = {West, T. and Hu, Y. and Verghese, P. B. and Bateman, R. J. and Braunstein, J. B. and Fogelman, I. and Budur, K. and Florian, H. and others}, title = {{Preclinical and Clinical Development of ABBV-8E12, a Humanized Anti-Tau Antibody, for Treatment of Alzheimer's Disease and Other Tauopathies}}, journal = {The journal of prevention of Alzheimer's disease}, year = {2017}, doi = {10.14283/jpad.2017.36}, pmid = {29181488}, url = {https://doi.org/10.14283/jpad.2017.36} } @article{nowell2023-36258018, author = {Nowell, J. and Blunt, E. and Edison, P.}, title = {{Incretin and insulin signaling as novel therapeutic targets for Alzheimer's and Parkinson's disease}}, journal = {Molecular psychiatry}, year = {2023}, doi = {10.1038/s41380-022-01792-4}, pmid = {36258018}, url = {https://doi.org/10.1038/s41380-022-01792-4} } @article{cummings2025-39971900, author = {Cummings, Jeffrey L and Zhou, Yadi and Van Stone, Alexandra and Cammann, Davis and Tonegawa-Kuji, Reina and Fonseca, Jorge and Cheng, Feixiong}, title = {{Drug repurposing for Alzheimer's disease and other neurodegenerative disorders}}, journal = {Nature communications}, year = {2025}, doi = {10.1038/s41467-025-56690-4}, pmid = {39971900}, url = {https://doi.org/10.1038/s41467-025-56690-4} } @article{santerre2026-42962966, author = {Santerre, Maryline and Shcherbik, Natalia and Sawaya, Bassel E}, title = {{The metabolic-brain axis: GLP-1 signaling, insulin resistance, and obesity pharmacotherapy in neurodegeneration}}, journal = {Metabolism: clinical and experimental}, year = {2026}, doi = {10.1016/j.metabol.2026.156810}, pmid = {42962966}, url = {https://doi.org/10.1016/j.metabol.2026.156810} } @article{tianhuikwan2020-33321511, author = {Tian Hui Kwan, A. and Arfaie, S. and Therriault, J. and Rosa-Neto, P. and Gauthier, S.}, title = {{Lessons Learnt from the Second Generation of Anti-Amyloid Monoclonal Antibodies Clinical Trials}}, journal = {Dementia and geriatric cognitive disorders}, year = {2020}, doi = {10.1159/000511506}, pmid = {33321511}, url = {https://doi.org/10.1159/000511506} } @article{zack2015-2d3045db, author = {Zack, Julia and Berg, Jolene and Juan, Axel and Pannacciulli, Nicola and Allard, Martine and Gottwald, Mildred and Zhang, Heather and Shao, Yongwu and others}, title = {{Pharmacokinetic drug–drug interaction study of ranolazine and metformin in subjects with type 2 diabetes mellitus}}, journal = {Clinical Pharmacology in Drug Development}, year = {2015}, doi = {10.1002/cpdd.174}, url = {https://doi.org/10.1002/cpdd.174} } @article{ayalon2021-33980574, author = {Ayalon, G. and Lee, S. H. and Adolfsson, O. and Foo-Atkins, C. and Atwal, J. K. and Blendstrup, M. and Booler, H. and Bravo, J. and others}, title = {{Antibody semorinemab reduces tau pathology in a transgenic mouse model and engages tau in patients with Alzheimer's disease}}, journal = {Science translational medicine}, year = {2021}, doi = {10.1126/scitranslmed.abb2639}, pmid = {33980574}, url = {https://doi.org/10.1126/scitranslmed.abb2639} } @article{wang2023-37730113, author = {Wang, Z. J. and Li, X. R. and Chai, S. F. and Li, W. R. and Li, S. and Hou, M. and Li, J. L. and Ye, Y. C. and others}, title = {{Semaglutide ameliorates cognition and glucose metabolism dysfunction in the 3xTg mouse model of Alzheimer's disease via the GLP-1R/SIRT1/GLUT4 pathway}}, journal = {Neuropharmacology}, year = {2023}, doi = {10.1016/j.neuropharm.2023.109716}, pmid = {37730113}, url = {https://doi.org/10.1016/j.neuropharm.2023.109716} } @article{marasco2020-32840330, author = {Marasco, R. A.}, title = {{Current and evolving treatment strategies for the Alzheimer disease continuum}}, journal = {The American journal of managed care}, year = {2020}, doi = {10.37765/ajmc.2020.88481}, pmid = {32840330}, url = {https://doi.org/10.37765/ajmc.2020.88481} } @article{cummings2019-31062825, author = {Cummings, J and Blennow, K and Johnson, K and Keeley, M and Bateman, R J and Molinuevo, J L and Touchon, J and Aisen, P and others}, title = {{Anti-Tau Trials for Alzheimer's Disease: A Report from the EU/US/CTAD Task Force}}, journal = {The journal of prevention of Alzheimer's disease}, year = {2019}, doi = {10.14283/jpad.2019.14}, pmid = {31062825}, url = {https://doi.org/10.14283/jpad.2019.14} } @article{giagkou2019-31007097, author = {Giagkou, Nikolaos and Stamelou, Maria}, title = {{Emerging drugs for progressive supranuclear palsy}}, journal = {Expert opinion on emerging drugs}, year = {2019}, doi = {10.1080/14728214.2019.1609450}, pmid = {31007097}, url = {https://doi.org/10.1080/14728214.2019.1609450} } @article{jiang2019-31667754, author = {Jiang, Jie and Ravits, John}, title = {{Pathogenic Mechanisms and Therapy Development for C9orf72 Amyotrophic Lateral Sclerosis/Frontotemporal Dementia}}, journal = {Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics}, year = {2019}, doi = {10.1007/s13311-019-00797-2}, pmid = {31667754}, url = {https://doi.org/10.1007/s13311-019-00797-2} } @article{riedel2020-32091331, author = {Riedel, Gernot and Klein, Jochen and Niewiadomska, Grazyna and Kondak, Constantin and Schwab, Karima and Lauer, Dilyara and Magbagbeolu, Mandy and Steczkowska, Marta and others}, title = {{Mechanisms of Anticholinesterase Interference with Tau Aggregation Inhibitor Activity in a Tau-Transgenic Mouse Model}}, journal = {Current Alzheimer research}, year = {2020}, doi = {10.2174/1567205017666200224120926}, pmid = {32091331}, url = {https://doi.org/10.2174/1567205017666200224120926} } @article{athauda2016-26851597, author = {Athauda, D. and Foltynie, T.}, title = {{The glucagon-like peptide 1 (GLP) receptor as a therapeutic target in Parkinson's disease: mechanisms of action}}, journal = {Drug discovery today}, year = {2016}, doi = {10.1016/j.drudis.2016.01.013}, pmid = {26851597}, url = {https://doi.org/10.1016/j.drudis.2016.01.013} } @article{elghanam2024-38669547, author = {Elghanam, Y. and Purja, S. and Kim, E. Y.}, title = {{Biomarkers as Endpoints in Clinical Trials for Alzheimer's Disease}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2024}, doi = {10.3233/jad-240008}, pmid = {38669547}, url = {https://doi.org/10.3233/jad-240008} } @article{muralidharan2022-35285968, author = {Muralidharan, K. K. and Karumanchi, S. and Kowalski, K. 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