% alzhub.org library filter % Source: https://alzhub.org/research?category=biomarkers&year=2026 % 231 entries, in the order the page lists them. Built from alzhub.org's own records. % 1 entries have no readable author in the source record and carry no author field. @article{mielke2026-42509652, author = {Mielke, Michelle M and Gaussoin, Sarah A and Casanova, Ramon and Latham, Lauren A and Manson, JoAnn E and Mouton, Charles P and Ng, Ted K S and Rapp, Stephen R and others}, title = {{Alzheimer's blood-based biomarkers, incident dementia, and interactions with age, APOE status, and hormone therapy}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2026}, doi = {10.1002/alz.71704}, pmid = {42509652}, url = {https://doi.org/10.1002/alz.71704} } @article{lin2026-41587095, author = {Lin, Y. and Zhao, Z. and Zhu, N. and Garcia Ptacek, S. and Carrero, J. J. and Bruchfeld, A. and Eriksdotter, M. and Mielke, M. M. and others}, title = {{Kidney Function and Blood and Cerebrospinal Fluid Biomarkers in Alzheimer's Disease and Related Dementias: Systematic Review and Meta-Analysis}}, journal = {Journal of the American Society of Nephrology : JASN}, year = {2026}, doi = {10.1681/asn.0000001007}, pmid = {41587095}, url = {https://doi.org/10.1681/asn.0000001007} } @article{chen2026-42318558, author = {Chen, Xiaofen and Huang, Tingting and Shi, Chao and Xu, Shuizhi and Fan, Shuwei}, title = {{Diagnostic performance of plasma p-Tau217, p-Tau181, and p-Tau231 across the Alzheimer's disease continuum: a network meta-analysis}}, journal = {Frontiers in aging neuroscience}, year = {2026}, doi = {10.3389/fnagi.2026.1834591}, pmid = {42318558}, url = {https://doi.org/10.3389/fnagi.2026.1834591} } @article{sawyer2026-41824925, author = {Sawyer, Russell P and Blair, Jessica and Judd, Suzanne E and Olson, Nels C and Howard, Virginia J and Armstrong, Nicole D and Long, D Leann and Hyacinth, Hyacinth I and others}, title = {{Circulating Biomarkers of Neurodegeneration and All-Cause and Dementia-Specific Mortality}}, journal = {Neurology}, year = {2026}, doi = {10.1212/wnl.0000000000214752}, pmid = {41824925}, url = {https://doi.org/10.1212/wnl.0000000000214752} } @article{silvarodriguez2026-42483984, author = {Silva-Rodríguez, Jesús and Zhang, Linda and Kleineidam, Luca and López-González, Francisco J and Wagner-Reguero, Sonia and Martínez-Castillo, Minerva and Sogorb-Esteve, Aitana and Guamán-Chulunchana, Michelle E and others}, title = {{Prognostic value of plasma \%p-tau217 in cognitively unimpaired older adults}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2026}, doi = {10.1002/alz.71599}, pmid = {42483984}, url = {https://doi.org/10.1002/alz.71599} } @article{raket2026-41178353, author = {Raket, L. L. and Binette, A. P. and Mattsson-Carlgren, N. and Janelidze, S. and Zetterberg, H. and Ashton, N. J. and Blennow, K. and Stomrud, E. and others}, title = {{Estimating the time course of biomarker changes in Alzheimer's disease}}, journal = {Brain : a journal of neurology}, year = {2026}, doi = {10.1093/brain/awaf413}, pmid = {41178353}, url = {https://doi.org/10.1093/brain/awaf413} } @article{raket2026-42273802, author = {Raket, Lars L and Lu, Ming and Evans, Cynthia D and Zimmer, Jennifer A and Sparks, JonDavid and Collins, Emily C and Shcherbinin, Sergey and Wang, Hong and others}, title = {{Donanemab treatment effect by baseline tau burden and disease severity: Observations from the TRAILBLAZER-ALZ 2 trial}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2026}, doi = {10.1002/alz.71577}, pmid = {42273802}, url = {https://doi.org/10.1002/alz.71577} } @article{trares2026-42463545, author = {Trares, Kira and Duman, Deniz and Beyer, Léon and Michaelian, Johannes C and Stocker, Hannah and Holleczek, Bernd and Beyreuther, Konrad and Schöttker, Ben and others}, title = {{Predictive value of plasma p-tau217 for Alzheimer's dementia compared to other blood-based biomarkers}}, journal = {EMBO molecular medicine}, year = {2026}, doi = {10.1038/s44321-026-00483-9}, pmid = {42463545}, url = {https://doi.org/10.1038/s44321-026-00483-9} } @article{jiang2026-42208562, author = {Jiang, X. and Hoang, T. D. and Shaw, L. M. and Jacobs, D. R. and Nasrallah, I. M. and Bryan, R. N. and Yaffe, K.}, title = {{Alzheimer's disease neuropathology plasma biomarkers and cognition in midlife: a community-based cohort study}}, journal = {Lancet (London, England)}, year = {2026}, doi = {10.1016/s0140-6736(26)00515-5}, pmid = {42208562}, url = {https://doi.org/10.1016/s0140-6736(26)00515-5} } @article{kang2026-42535277, author = {Kang, Sung Hoon and Park, Yu Jeong and Lee, Seungyun and Kang, Jimin and Lee, Seongin and Lee, Eun Seong and Jung, Hye Na and Ryoo, Inseon and others}, title = {{Heterogeneity in plasma p-tau217 response and its association with cognitive trajectories under lecanemab treatment}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2026}, doi = {10.1002/alz.71705}, pmid = {42535277}, url = {https://doi.org/10.1002/alz.71705} } @article{kim2026-41913058, author = {Kim, Hairin and Soberanes, Daniel and Jutten, Roos J and Dubbelman, Mark A and Yang, Hyun-Sik and Marshall, Gad A and Johnson, Keith A and Betensky, Rebecca A and others}, title = {{Combining p-tau217 and digital cognitive testing to predict cognitive decline}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2026}, doi = {10.1002/alz.71328}, pmid = {41913058}, url = {https://doi.org/10.1002/alz.71328} } @article{vonarnim2026-42518233, author = {von Arnim, Christine A F and Sadlonova, Monika and Derad, Carlotta and Hohberg, Maike and Celano, Christopher M and Günther, Irina and Titsch, Tobias and Krasiuk, Iryna and others}, title = {{Plasma Amyloid-β 1-40 and Postoperative Delirium After Cardiac Surgery}}, journal = {JAMA network open}, year = {2026}, doi = {10.1001/jamanetworkopen.2026.25730}, pmid = {42518233}, url = {https://doi.org/10.1001/jamanetworkopen.2026.25730} } @article{mattssoncarlgren2026-41864233, author = {Mattsson-Carlgren, Niklas and Palmqvist, Sebastian and Horie, Kanta and Barthélemy, Nicolas and Salvadó, Gemma and Binette, Alexa Pichet and Tideman, Pontus and Morris, John C and others}, title = {{Integration of plasma eMTBR-tau243 and p-tau217 in the diagnosis and stratification of Alzheimer's disease: a prospective cohort study}}, journal = {The Lancet. Neurology}, year = {2026}, doi = {10.1016/S1474-4422(26)00029-3}, pmid = {41864233}, url = {https://doi.org/10.1016/S1474-4422(26)00029-3} } @article{malekahmadi2026-41324928, author = {Malek-Ahmadi, M. and Sharma, S. and Stipho, F. and Denkinger, M. and Singh, A. and Brum, W. S. and Ashton, N. J.}, title = {{Plasma Phosphorylated Tau 217 and Amyloid Burden in Older Adults Without Cognitive Impairment: A Meta-Analysis}}, journal = {JAMA neurology}, year = {2026}, doi = {10.1001/jamaneurol.2025.4721}, pmid = {41324928}, url = {https://doi.org/10.1001/jamaneurol.2025.4721} } @article{kang2026-41612483, author = {Kang, S. H. and Kim, S. and Kim, Y. J. and Yoo, H. and Lee, E. H. and Jang, H. and Shin, D. and Yun, J. and others}, title = {{Glymphatic dysfunction links vascular pathology to Alzheimer's biomarkers and cognitive decline}}, journal = {Alzheimer's research \& therapy}, year = {2026}, doi = {10.1186/s13195-026-01964-2}, pmid = {41612483}, url = {https://doi.org/10.1186/s13195-026-01964-2} } @article{sun2026-41854616, author = {Sun, Haoqi and Milton, Sasha and Fang, Yi and Taha, Hash Brown and Shiju, Shreya and Thomas, Robert J and Ganglberger, Wolfgang and Pase, Matthew P and others}, title = {{Machine Learning-Based Sleep Electroencephalographic Brain Age Index and Dementia Risk: An Individual Participant Data Meta-Analysis}}, journal = {JAMA network open}, year = {2026}, doi = {10.1001/jamanetworkopen.2026.1521}, pmid = {41854616}, url = {https://doi.org/10.1001/jamanetworkopen.2026.1521} } @article{study2026-42163294, title = {{Plasma p-tau217, p-tau181, and Aβ42 predict amyloid PET positivity in cognitively unimpaired adults}}, journal = {Alzheimer's research \& therapy}, year = {2026}, doi = {10.1186/s13195-026-02080-x}, pmid = {42163294}, url = {https://doi.org/10.1186/s13195-026-02080-x} } @article{jiang2026-42601653, author = {Jiang, Mingxing and Lan, Guoyu and Zhu, Jiayi and Zhang, Laihong and Li, Anqi and He, Zhengbo and Zhu, Yalin and Zhou, Xin and others}, title = {{Cross-Sectional and Longitudinal Diagnostic Performance of Plasma p-tau217 and p-tau217/Aβ42 in Alzheimer's Disease}}, journal = {Annals of neurology}, year = {2026}, doi = {10.1002/ana.78322}, pmid = {42601653}, url = {https://doi.org/10.1002/ana.78322} } @article{tropea2026-41848292, author = {Tropea, Thomas F and Stevenson, Patricia Aldea and Flitter, Matthew and Meehan, David and Morris, Amanda and Lu, Ming and Iaccarino, Leonardo and Collins, Emily C and others}, title = {{Association between Plasma P-tau217 and Alzheimer's Copathology and Cognitive Decline in Parkinson's Disease}}, journal = {Annals of neurology}, year = {2026}, doi = {10.1002/ana.78201}, pmid = {41848292}, url = {https://doi.org/10.1002/ana.78201} } @article{petersen2026-41714746, author = {Petersen, Kellen K and Milà-Alomà, Marta and Li, Yan and Du, Lianlian and Xiong, Chengjie and Tosun, Duygu and Saef, Benjamin and Saad, Ziad S and others}, title = {{Predicting onset of symptomatic Alzheimer's disease with plasma p-tau217 clocks}}, journal = {Nature medicine}, year = {2026}, doi = {10.1038/s41591-026-04206-y}, pmid = {41714746}, url = {https://doi.org/10.1038/s41591-026-04206-y} } @article{chen2026-41478832, author = {Chen, Xuhui and Jiang, Mingxing and Zhang, Laihong and Zhu, Jiayi and Li, Anqi and He, Zhengbo and Zhou, Xin and Zhu, Yalin and others}, title = {{Association of plasma p-tau and p-tau/Aβ ratio with Alzheimer's pathology}}, journal = {The journal of prevention of Alzheimer's disease}, year = {2026}, doi = {10.1016/j.tjpad.2025.100472}, pmid = {41478832}, url = {https://doi.org/10.1016/j.tjpad.2025.100472} } @article{belder2026-42637536, author = {Belder, Christopher R S and Heslegrave, Amanda J and Swann, Owen and Abel, Emily and Beament, Millie and Nasir, Moneeb and Rice, Helen and Weston, Philip S J and others}, title = {{Presymptomatic plasma biomarkers in autosomal dominant Alzheimer's disease: sequence and timing}}, journal = {Journal of neurology, neurosurgery, and psychiatry}, year = {2026}, doi = {10.1136/jnnp-2026-339037}, pmid = {42637536}, url = {https://doi.org/10.1136/jnnp-2026-339037} } @article{shadyab2026-41805953, author = {Shadyab, A. H. and Zhang, B. and LaCroix, A. Z. and Mielke, M. M. and Resnick, S. M. and Nguyen, S. and Ferrucci, L. and Libermann, T. A. and Ngo, L. and Casanova, R. and others}, title = {{Plasma Phosphorylated Tau 217 and Incident Mild Cognitive Impairment and Dementia in Older Women}}, journal = {JAMA Network Open}, year = {2026}, doi = {10.1001/jamanetworkopen.2026.1295}, pmid = {41805953}, url = {https://doi.org/10.1001/jamanetworkopen.2026.1295} } @article{coughlan2026-41697669, author = {Coughlan, Gillian T and Ourry, Valentin and Townsend, Diana and Klinger, Hannah and Brown, Jane A and Cuppels, Madison and Betthauser, Tobey and Langhough, Rebecca and others}, title = {{Sex Differences in P-Tau217, Tau Aggregation, and Cognitive Decline}}, journal = {JAMA neurology}, year = {2026}, doi = {10.1001/jamaneurol.2025.5670}, pmid = {41697669}, url = {https://doi.org/10.1001/jamaneurol.2025.5670} } @article{salvado2026-42189519, author = {Salvadó, G. and Horie, K. and Barthélemy, N. R. and Schindler, S. E. and Janelidze, S. and Orduña Dolado, A. and Bali, D. and Perrin, R. J. and Morris, J. C. and Benzinger, T. L. S. and Gordon, B. A. and Stomrud, E. and others}, title = {{Plasma eMTBR-tau243 and \%p-tau217 for Biological Staging of Alzheimer Disease}}, journal = {JAMA Neurology}, year = {2026}, doi = {10.1001/jamaneurol.2026.1405}, pmid = {42189519}, url = {https://doi.org/10.1001/jamaneurol.2026.1405} } @article{phillips2026-42387213, author = {Phillips, Bridget and Sanford, Jessie and Janve, Vaibhav A and Liu, Menghan and Johnson, Matt and Gong, Katherine and Bergmann, Kristy and Lowery, Joseph and others}, title = {{Blood-based circular RNAs for early diagnosis of Alzheimer's disease}}, journal = {Nature medicine}, year = {2026}, doi = {10.1038/s41591-026-04485-5}, pmid = {42387213}, url = {https://doi.org/10.1038/s41591-026-04485-5} } @article{chen2026-41804834, author = {Chen, Shuai and Hao, Xiaodi and Ma, Kai and Li, Rong and Wen, Changming and Han, Xinsheng and Zheng, Wenquan and Ruan, Shiwang and others}, title = {{Implementing plasma p-tau217 and cognitive testing for Alzheimer's screening in low-education populations in central China}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2026}, doi = {10.1002/alz.71251}, pmid = {41804834}, url = {https://doi.org/10.1002/alz.71251} } @article{xie2026-42021299, author = {Xie, Siqi and Liang, Yumei and Pang, Yana and Li, Ying and Cao, Shuman and Li, Yan and Wang, Qi and Moghekar, Abhay and others}, title = {{Plasma biomarker trajectories across Alzheimer's clinical onset: a 17-year prospective study}}, journal = {Alzheimer's research \& therapy}, year = {2026}, doi = {10.1186/s13195-026-02045-0}, pmid = {42021299}, url = {https://doi.org/10.1186/s13195-026-02045-0} } @article{buckley2026-42449500, author = {Buckley, Rachel F and Townsend, Diana L and Birkenbihl, Colin J and Cuppels, Madison and Coughlan, Gillian T and Seto, Mabel T and Brown, Jane A and Properzi, Michael J and others}, title = {{Prognostic Value of Blood-Based P-Tau217 Levels for Progression to Cognitive Impairment}}, journal = {JAMA}, year = {2026}, doi = {10.1001/jama.2026.12556}, pmid = {42449500}, url = {https://doi.org/10.1001/jama.2026.12556} } @article{kivisakk2026-41610380, author = {Kivisäkk, Pia and Fatima, Hadia A. and Wu, Chao‐Yi and Padmanabhan, Nikhil and Romero, Daniel and Gorham, Taron and Weik, Molly and Dodge, Hiroko H. and others}, title = {{Postmortem Associations Between Alzheimer Disease Pathology and Plasma pTau217, GFAP, and NfL in AD and AD-Related Dementias}}, journal = {Neurology}, year = {2026}, doi = {10.1212/wnl.0000000000214351}, pmid = {41610380}, url = {https://doi.org/10.1212/wnl.0000000000214351} } @article{arranz2026-42435584, author = {Arranz, Javier and Lantero-Rodríguez, Juan and Braun-Wohlfahrt, Luisa Sophie and Vaqué-Alcázar, Lídia and Rodríguez-Baz, Íñigo and Kac, Przemysław R and Arslan, Burak and Maure-Blesa, Lucía and others}, title = {{CSF and plasma tau biomarkers in the Down syndrome-Alzheimer's disease continuum}}, journal = {EBioMedicine}, year = {2026}, doi = {10.1016/j.ebiom.2026.106370}, pmid = {42435584}, url = {https://doi.org/10.1016/j.ebiom.2026.106370} } @article{agosta2026-41857623, author = {Agosta, Federica and Cecchetti, Giordano and Spinelli, Edoardo G and Ghirelli, Alma and Rugarli, Giulia and Pisano, Stefano and Coraglia, Federico and Canu, Elisa and others}, title = {{Real-world implementation of lecanemab and donanemab in an Italian memory center: a 1-year experience}}, journal = {Alzheimer's research \& therapy}, year = {2026}, doi = {10.1186/s13195-026-02015-6}, pmid = {41857623}, url = {https://doi.org/10.1186/s13195-026-02015-6} } @article{feizpour2026-41478830, author = {Feizpour, Azadeh and Doré, Vincent and Bourgeat, Pierrick and Doecke, James D and Canovas, Rodrigo and Laws, Simon M and Porter, Tenielle and Huang, Kun and others}, title = {{Plasma Aβ42/40 predicts progression from Aβ-amyloid negative to positive PET scans}}, journal = {The journal of prevention of Alzheimer's disease}, year = {2026}, doi = {10.1016/j.tjpad.2025.100455}, pmid = {41478830}, url = {https://doi.org/10.1016/j.tjpad.2025.100455} } @article{kasuga2026-41653881, author = {Kasuga, Kensaku and Kikuchi, Masataka and Kikkawa-Saito, Emiko and Tsukie, Tamao and Ishiguro, Takanobu and Miyashita, Akinori and Iwatsubo, Takeshi and {Japanese Alzheimer’s Disease Neuroimaging Initiative} and others}, title = {{Evaluation of plasma p-tau217 biomarkers in detecting amyloid pathology and predicting cognitive outcomes: Observations from Japanese Alzheimer's disease neuroimaging initiative cohort}}, journal = {The journal of prevention of Alzheimer's disease}, year = {2026}, doi = {10.1016/j.tjpad.2026.100502}, pmid = {41653881}, url = {https://doi.org/10.1016/j.tjpad.2026.100502} } @article{valletta2026-41996117, author = {Valletta, Martina and Vetrano, Davide Liborio and Qiu, Chengxuan and Canevelli, Marco and Miccoli, Edoardo and Andersson, Sarah Wamala and Fredolini, Claudia and Bruno, Giuseppe and others}, title = {{Anemia and Blood Biomarkers of Alzheimer Disease in Dementia Development}}, journal = {JAMA Network Open}, year = {2026}, doi = {10.1001/jamanetworkopen.2026.4029}, pmid = {41996117}, url = {https://doi.org/10.1001/jamanetworkopen.2026.4029} } @article{cottez2026-42273887, author = {Cottez, Rosalie J and Peyrot, Clémence and Denis, Hélèna L and Tremblay, Cyntia and Loiselle, Andréanne and Dallaire-Théroux, Caroline and Filali-Mouhim, Ali and Hébert, Sébastien S and others}, title = {{Plasma p-tau markers, vascular factors, and cognitive decline in the CIMA-Q cohort}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2026}, doi = {10.1002/alz.71588}, pmid = {42273887}, url = {https://doi.org/10.1002/alz.71588} } @article{kim2026-41804841, author = {Kim, Jun Pyo and Song, Minku and Cho, Minyoung and Lee, Hyunwoo and Jung, Sang-Hyuk and Lim, Soohyun and Kim, Chanhee and Jang, Beomjin and others}, title = {{Genetic architecture of plasma pTau217 and related biomarkers in Alzheimer's disease via genome-wide association studies}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2026}, doi = {10.1002/alz.71275}, pmid = {41804841}, url = {https://doi.org/10.1002/alz.71275} } @article{smith2026-41963316, author = {Smith, Alena M and Lorkiewicz, Sara A and Arslan, Burak and Montoliu-Gaya, Laia and Ashton, Nicholas J and Wilson, Edward N and Alcolea, Daniel and Rodríguez-Baz, Íñigo and others}, title = {{Plasma phosphorylated tau 217 detects amyloid-β in neuronal synuclein disease}}, journal = {NPJ Parkinson's disease}, year = {2026}, doi = {10.1038/s41531-026-01341-8}, pmid = {41963316}, url = {https://doi.org/10.1038/s41531-026-01341-8} } @article{pauley2026-42558640, author = {Pauley, Meghan E and Coughlan, Christina and Dong, Fran and Bucca, Brian and Tanner, Bailey and Chartier-Logan, Catherine and Shapiro, Allison L B and Snell-Bergeon, Janet K}, title = {{Type 1 diabetes is associated with higher plasma levels of biomarkers of neurodegeneration and neuroinflammation}}, journal = {Frontiers in immunology}, year = {2026}, doi = {10.3389/fimmu.2026.1860993}, pmid = {42558640}, url = {https://doi.org/10.3389/fimmu.2026.1860993} } @article{liu2026-42158847, author = {Liu, Caiyan and Cheng, Anqi and Zou, Yinxi and Wang, Hebo and Ai, Zhibing and Wu, Shiwen and Liu, Linwen and Li, Mingli and others}, title = {{Plasma biomarkers of neurodegeneration and neuroinflammation in intracranial atherosclerotic disease}}, journal = {Brain communications}, year = {2026}, doi = {10.1093/braincomms/fcag125}, pmid = {42158847}, url = {https://doi.org/10.1093/braincomms/fcag125} } @article{silvaspinola2026-41535718, author = {Silva-Spínola, Anuschka and Durães, João and de Oliveira, João Pedro Guedes and Tábuas-Pereira, Miguel and Lima, Marisa and de Mendonça, Alexandre and Santana, Isabel and Baldeiras, Inês}, title = {{Plasma p-tau217, quantified by the fully automated LUMIPULSE G platform, outperforms p-tau181 in predicting amyloid pathology in cognitive complaints patients}}, journal = {Scientific reports}, year = {2026}, doi = {10.1038/s41598-025-34241-7}, pmid = {41535718}, url = {https://doi.org/10.1038/s41598-025-34241-7} } @article{sewell2026-41980229, author = {Sewell, Kelsey R. and Solis‐Urra, Patricio and Huang, Haiqing and Karikari, Thomas K. and Grove, George and Kramer, Arthur F. and McAuley, Edward and Burns, Jeffrey Murray and others}, title = {{Cognitive and Brain Reserve as Modifiers of Early Alzheimer Disease–Related Cognitive Vulnerability}}, journal = {Neurology}, year = {2026}, doi = {10.1212/wnl.0000000000214833}, pmid = {41980229}, url = {https://doi.org/10.1212/wnl.0000000000214833} } @article{benina2026-41562409, author = {Benina, Natalya and Buitrago, Luna and De Simone, Francesca I and Radwan, Rachel R and Miller, M Craig and Martin, Katie and Dickson, Diana and Ho, Sara and others}, title = {{Plasma pTau 217/β-amyloid 1-42 ratio for enhanced accuracy and reduced uncertainty in detecting amyloid pathology}}, journal = {Brain : a journal of neurology}, year = {2026}, doi = {10.1093/brain/awag001}, pmid = {41562409}, url = {https://doi.org/10.1093/brain/awag001} } @article{piura2026-42619350, author = {Piura, Yoav D and Aduen, Paula A and Schecter, Leah and Jain, Manoj K and Algeciras-Schimnich, Alicia and Figdore, Daniel J and Bornhorst, Joshua and Petersen, Ronald C and others}, title = {{Optimized plasma p-tau217 and p-tau217/Aβ42 cutoffs enhance detection of pre-clinical Alzheimer's disease across diverse participants}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2026}, doi = {10.1002/alz.71763}, pmid = {42619350}, url = {https://doi.org/10.1002/alz.71763} } @article{giacomucci2026-41700306, author = {Giacomucci, Giulia and Tabbì, Silvia Maria Rita and Ingannato, Assunta and Bagnoli, Silvia and Padiglioni, Sonia and Crucitti, Chiara and Sensi, Chiara and Sanesi, Serena and others}, title = {{Refining Alzheimer's disease biological diagnosis with plasma biomarkers: Resolving p-tau217 "gray zone" with p-tau181 integration}}, journal = {Alzheimer's \& dementia (Amsterdam, Netherlands)}, year = {2026}, doi = {10.1002/dad2.70285}, pmid = {41700306}, url = {https://doi.org/10.1002/dad2.70285} } @article{oberlin2026-42151104, author = {Oberlin, Lauren E and Solis-Urra, Patricio and Sewell, Kelsey R and Collins, Audrey M and Kang, Chaeryon and Huang, Haiqing and Grove, George and Wan, Lu and others}, title = {{Physical activity, aerobic fitness, and AD blood biomarkers: The IGNITE study}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2026}, doi = {10.1002/alz.71484}, pmid = {42151104}, url = {https://doi.org/10.1002/alz.71484} } @article{moghekar2026-42418465, author = {Moghekar, Abhay R and Rock, James A and Mohs, Richard C and Hansson, Oskar and Stomrud, Erik and Palmqvist, Sebastian and Mattsson-Carlgren, Niklas and Johnson, Sterling C and others}, title = {{Multicenter validation of plasma p-tau217/ amyloid beta 1-42 ratio in symptomatic Alzheimer's disease}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2026}, doi = {10.1002/alz.71644}, pmid = {42418465}, url = {https://doi.org/10.1002/alz.71644} } @article{ritchie2026-42719535, author = {Ritchie, Craig and Hortsch, Sayuri and Quijano-Rubio, Clara and Menzel, Patrick and Kirste, Imke and Caley, David and Burke, Anna D and Rowe, Christopher C and others}, title = {{Elecsys pT181p immunoassay: Clinical performance for ruling out amyloid pathology}}, journal = {Alzheimer's \& dementia (Amsterdam, Netherlands)}, year = {2026}, doi = {10.1002/dad2.70439}, pmid = {42719535}, url = {https://doi.org/10.1002/dad2.70439} } @article{deek2026-c113f7bd, author = {Deek, Rebecca A. and Balogun, Wasiu G. and Zeng, Xuemei and Triana-Baltzer, Gallen and Pascoal, Tharick A. and Kolb, Hartmuth C. and Snitz, Beth and Cohen, Ann D. and Karikari, Thomas K.}, title = {{Head-to-head comparison of plasma p-tau217 immunoassays for incipient Alzheimer's disease in community cohorts}}, journal = {Alzheimer's Research \& Therapy}, year = {2026} } @article{huber2026-41491101, author = {Huber, H. and Montoliu-Gaya, L. and Brum, W. 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M. and Sikkes, S. A. and Heymans, M. W. and Hulsman, M. and Tesi, N. and Gouda, M. and Graat, M. J. and van der Hoorn, M. E. and others}, title = {{Plasma neurofilament light links mortality to neuroaxonal injury beyond clinical decline and Alzheimer disease plasma biomarkers: a multi-cohort study of oldest old individuals}}, journal = {medRxiv}, year = {2026}, doi = {10.64898/2026.10.17.26365798}, url = {https://doi.org/10.64898/2026.10.17.26365798} } @article{kang2026-25f2d41d, author = {Kang, M. J. and Eratne, D. and Borchard, T. and Patel, K. and Malpas, C. B. and Dang, C. and Storer, M. and Bhalala, O. G. and others}, title = {{Plasma Neurofilament Light Chain is Markedly Elevated in General Hospital Inpatients with Delirium}}, journal = {medRxiv}, year = {2026}, doi = {10.64898/2026.10.18.26365854}, url = {https://doi.org/10.64898/2026.10.18.26365854} } @article{stubs2026-d52f05ae, author = {Stubs, J. and Langballe, E. M. and Livingston, G. and Anstey, K. J. and Deckers, K. and Kivimäki, M. and Strand, B. H. and Sunde, A. L. and others}, title = {{Comparative analysis of plasma pTau217, NfL and eight modifiable risk scores for 11-year dementia prediction in the HUNT Study}}, journal = {medRxiv}, year = {2026}, doi = {10.64898/2026.10.15.26365615}, url = {https://doi.org/10.64898/2026.10.15.26365615} } @article{tristaopereira2026-b88d713c, author = {Tristão-Pereira, C. and Silva, G. and Lopez, K. A. and Ku, V. and Gonzalez, A. and Martinez, J. E. and Giudicessi, A. and Rowe, M. and others}, title = {{Alzheimer’s disease blood-based biomarkers in the Boston Latino Aging Study (BLAST): Associations with cognition and depressive symptoms}}, journal = {medRxiv}, year = {2026}, doi = {10.64898/2026.10.13.26365304}, url = {https://doi.org/10.64898/2026.10.13.26365304} } @article{cabezasvinueza2026-ca662b7e, author = {Cabezas-Vinueza, L. P. and Rivoira, M. A. and RdlB, Garzón and Rodríguez-Bies, E. and Alarcón Rubio, D. and Amian, J. G. and Fernandez-Portero, C. and López-Lluch, G.}, title = {{Blood Plasma Coenzyme Q 10 and P-Selectin Are Predictive Factors for Mild Cognitive Dysfunction in Elderly Women}}, journal = {Preprints.org}, year = {2026}, doi = {10.20944/preprints202610.1228.v1}, url = {https://doi.org/10.20944/preprints202610.1228.v1} } @article{elsalamony2026-a10c51b4, author = {EL-Salamony, G. I. and Mohamed, R. H. and Saad, R. A. and Tarek, M. and Fawzy, N. M. and Elnahas, E. M.}, title = {{Neuroprotective Role of Vitamin D Against LPS-Induced Cognitive Deficits in Rats: Targeting Hippocampal PERK-ATF4-CHOP-Mediated ER Stress and Calcium Dyshomeostasis}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10413434/v1}, url = {https://doi.org/10.21203/rs.3.rs-10413434/v1} } @article{rosenberg2026-f728d2cc, author = {Rosenberg, A. and Solomon, A. and Matton, A. and Lehtisalo, J. and Benedet, A. L. and Mangialasche, F. and Levälahti, E. and Arslan, B. and others}, title = {{Blood Biomarkers of Alzheimer’s Disease Neuropathology, Cognition, and Response to a Multidomain Lifestyle Intervention: Secondary analysis of the FINGER Randomized Controlled Dementia Risk Reduction Trial}}, journal = {medRxiv}, year = {2026}, doi = {10.64898/2026.10.02.26364486}, url = {https://doi.org/10.64898/2026.10.02.26364486} } @article{abdo2026-806f3501, author = {Abdo, A. N. and Cho, S. and Ge, Y. and Duan, H. and Gabr, M. T.}, title = {{A First-in-Class, Brain-Penetrant Small Molecule Inhibitor of the NOS1AP-Tau Interaction Rescues Tau Pathology In Vivo and Improves Cognition}}, journal = {bioRxiv}, year = {2026}, doi = {10.64898/2026.10.01.755865}, url = {https://doi.org/10.64898/2026.10.01.755865} } @article{lee2026-4cc33be6, author = {Lee, Y. and Zeng, X. and Farinas, M. F. and Lopresti, B. J. and Habte, R. F. and Wilckens, K. A. and Karikari, T. K.}, title = {{Analytical performance of a delayed-centrifugation blood collection tube for remote blood biomarker assessment}}, journal = {medRxiv}, year = {2026}, doi = {10.64898/2026.10.05.26364780}, url = {https://doi.org/10.64898/2026.10.05.26364780} } @article{sharma2026-c65529a9, author = {Sharma, R. U. and Tolosa-Tort, P. and Okorie, M. and Chatterjee, A. and Jonson, C. and Yaffe, K. and Belloy, M. E. and Andrews, S. J. and others}, title = {{Sex differences in genetic liability to modifiable Alzheimer’s disease risk factors}}, journal = {medRxiv}, year = {2026}, doi = {10.64898/2026.10.01.26364536}, url = {https://doi.org/10.64898/2026.10.01.26364536} } @article{soderstrom2026-f55806d2, author = {Soderstrom, K. and Litwa, K. A.}, title = {{Cannabidiol for chronic neuroinflammation: clinical pharmacology and what an interpretable trial will require}}, journal = {Authorea Preprints}, year = {2026}, doi = {10.22541/authorea.15009897/v1}, url = {https://doi.org/10.22541/authorea.15009897/v1} } @article{vanschaik2026-b4bfc569, author = {van Schaik, M. and Lai, K. O. and Shapiro, N. L. and Jäck, A. and Goddard, J. and Crook, H. and Frohn, R. and Jones, P. 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L. and Saito, M. R.}, title = {{T1R2/T1R3 Identified as the Aβ Receptor: A New Mechanism Linking Aβ42/40 Ratio to Neuronal Hyperexcitability in Alzheimer’s Disease}}, journal = {bioRxiv}, year = {2026}, doi = {10.64898/2026.09.25.754367}, url = {https://doi.org/10.64898/2026.09.25.754367} } @article{zheng2026-ada7a142, author = {Zheng, L. and Ghanbarian, E. and Albarrán Morillo, C. and Younes, K. and Glover, C. M. and Rabin, L. A. and Grill, J. D. and Ewers, M. and others}, title = {{Tau-PET subtype modifies the association between plasma p-tau217 and memory in Alzheimer’s disease}}, journal = {medRxiv}, year = {2026}, doi = {10.64898/2026.09.25.26363629}, url = {https://doi.org/10.64898/2026.09.25.26363629} } @article{huang2026-23883748, author = {Huang, Y. and Toga, A. W. and Zhao, L. and {the Alzheimer’s Disease Neuroimaging Initiative}}, title = {{White Matter Slow-4 fALFF as a Complementary Marker in the Multimodal Alzheimer’s Disease Biomarker Landscape}}, journal = {bioRxiv}, year = {2026}, doi = {10.64898/2026.09.17.752468}, url = {https://doi.org/10.64898/2026.09.17.752468} } @article{chen2026-074ef6d2, author = {Chen, S. and Wang, M. and Ji, Y.}, title = {{Plasma Fibrinogen Correlates with Aβ Clearance of monocytes and AD Biomarkers in Cognitively Normal Individuals}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10658330/v1}, url = {https://doi.org/10.21203/rs.3.rs-10658330/v1} } @article{bernardi2026-632475b0, author = {Bernardi, E. and Arranz, J. and Rubio-Guerra, S. and García-Castro, J. and Maure-Blesa, L. and Rodríguez-Baz, I. and Peris-Subiza, J. and Selma-González, J. and others}, title = {{Does CSF testing add value after an indeterminate plasma p-tau217 result?}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10754560/v1}, url = {https://doi.org/10.21203/rs.3.rs-10754560/v1} } @article{hey2026-a02492d7, author = {Hey, J. 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D.}, title = {{Clinically Relevant Biomarkers of Alzheimer's Disease Are Associated with Age and Cortical Atrophy in Chimpanzees ( Pan troglodytes )}}, journal = {bioRxiv}, year = {2026}, doi = {10.64898/2026.08.12.744516}, url = {https://doi.org/10.64898/2026.08.12.744516} } @article{malotaux2026-6c38e2c0, author = {Malotaux, V. and Tristão-Pereira, C. and Zuluaga, Y. and Munoz, C. and Guerrero, A. and Bocanegra, Y. and Alzate, D. and Serna, L. and others}, title = {{Plasma Biomarker Profiles in a Colombian Cohort of Heterozygous APOE3-Christchurch Carriers}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10705602/v1}, url = {https://doi.org/10.21203/rs.3.rs-10705602/v1} } @article{yan2026-d8ff574a, author = {Yan, J. and Wang, Y. and Han, H. and Zhao, T. and Liu, D. and Chai, T. and Zhou, Y. and Yan, K. and others}, title = {{Diagnostic Concordance Between Plasma p-Tau217 and Amyloid-β Biomarkers in Symptomatic Alzheimer's Disease: Evidence From a Chinese Cohort}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10410778/v1}, url = {https://doi.org/10.21203/rs.3.rs-10410778/v1} } @article{floresromero2026-1c8d3cb2, author = {Flores Romero, K. 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J. and Hoang, T. and Bae, S. and Yaffe, K.}, title = {{Epigenetic Clock Trajectories and Brain Health in Midlife}}, journal = {medRxiv}, year = {2026}, doi = {10.64898/2026.07.16.26358251}, url = {https://doi.org/10.64898/2026.07.16.26358251} } @article{chan2026-7050e06c, author = {Chan, J. W. and Corradetti, G. and Soylu, C. and Almidani, L. and Wu, X. and Wang, Z. C. and Astraea, N. and Hu, Z. and others}, title = {{Neurovascular Outer Retinal Degeneration in Presymptomatic Alzheimer’s Disease: An Oculomic Biomarker Study}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10251231/v2}, url = {https://doi.org/10.21203/rs.3.rs-10251231/v2} } @article{alldritt2026-e9617661, author = {Alldritt, I. and Michaelian, J. C. and Yu, R. and Deemer, S. E. and Mills, R. J. and Naismith, S. L. and Philp, A.}, title = {{Plasma metabolomic profiling of frailty in older adults at risk of dementia}}, journal = {medRxiv}, year = {2026}, doi = {10.64898/2026.10.06.26364906}, url = {https://doi.org/10.64898/2026.10.06.26364906} } @article{sulter2026-8b77381d, author = {Sulter, G. A.}, title = {{Chronic Migraine and Alzheimer’s Dementia: A Candidate Mechanistic Route, and the Evidence That Would Test It}}, journal = {Preprints.org}, year = {2026}, doi = {10.20944/preprints202605.0132.v2}, url = {https://doi.org/10.20944/preprints202605.0132.v2} } @article{seerleynolan2026-6e1d26a2, author = {Seerley Nolan, A. L. and McElroy, S. D. and Mace, A. A. and Grindeland Panter, A. 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X. and Silver, S. and Eimicke, J. and Simoes, S. and others}, title = {{Association of total and brain-derived Alzheimer’s disease plasma biomarkers with brain amyloid deposition in a community-based sample}}, journal = {medRxiv}, year = {2026}, doi = {10.64898/2026.07.29.26359150}, url = {https://doi.org/10.64898/2026.07.29.26359150} } @article{yam2026-aa6728f4, author = {Yam, A. T. Y. and Chai, Y. L. and Hilal, S. and Yuan, C. and Mok, V. C. T. and Venketasubramanian, N. and Tan, B. Y. and Sim, M. A. and others}, title = {{Decreased Plasma IGF-1 Is Associated with Cortical Atrophy, But Not Concomitant Cerebrovascular Disease in Alzheimer’s Dementia}}, journal = {Preprints.org}, year = {2026}, doi = {10.20944/preprints202607.1813.v1}, url = {https://doi.org/10.20944/preprints202607.1813.v1} } @article{subbulakshmi2026-11572edc, author = {Subbulakshmi, S. and Park, J. and Rathmann-Bloch, J. and Ward, T. and Cheng, G. L. and Miller, D. S. and Schwartz, S. T. and Sheng, J. and others}, title = {{Dissociable structural and molecular pathways of age-related variability in sustained attention}}, journal = {bioRxiv}, year = {2026}, doi = {10.64898/2026.06.29.735429}, url = {https://doi.org/10.64898/2026.06.29.735429} } @article{lang2026-9b971246, author = {Lang, Y. R. and Vrillon, A. and Pasternak, S. and Blazhenets, G. and Soleimani-Meigooni, D. and Ravinovici, G. D. and Weiner, M. 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D. and Drake, C. and Adkin, P. and others}, title = {{Proteomic biomarkers of cognitive function, APOE ε4 status, and dementia in Generation Scotland}}, journal = {medRxiv}, year = {2026}, doi = {10.64898/2026.01.27.26344912}, url = {https://doi.org/10.64898/2026.01.27.26344912} } @article{chea2026-2e7985ea, author = {Chea, E. F.}, title = {{ATN Classification and Machine-Learned Plasma Biomarker Phenotypes Reveal Distinct Alzheimer’s Pathology in a Population-Based Cohort}}, journal = {medRxiv}, year = {2026}, doi = {10.64898/2026.01.02.26343331}, url = {https://doi.org/10.64898/2026.01.02.26343331} } @article{slama2026-e37446c9, author = {Slama, P. S. and Macbale, A. R. and Jedynak, B. M.}, title = {{Association of infections and autoimmune conditions with cognition: a study using self-reported conditions and identifying a novel plasma biomarker}}, journal = {medRxiv}, year = {2026}, doi = {10.64898/2026.02.13.26346282}, url = {https://doi.org/10.64898/2026.02.13.26346282} } @article{rowsthorn2026-13371cc5, author = {Rowsthorn, E. and Xia, Y. and Breakspear, M. and Fripp, J. and Robinson, G. A. and Ashton, N. and Zetterberg, H. and Lupton, M. K. and others}, title = {{Multimodal latent composites are associated with cognition and Alzheimer’s disease dementia: a framework for systems-level brain health}}, journal = {medRxiv}, year = {2026}, doi = {10.64898/2026.02.21.26346745}, url = {https://doi.org/10.64898/2026.02.21.26346745} } @article{insel2026-7d6ebedf, author = {Insel, P. S. and Donohue, M. C.}, title = {{Predicting the age of Alzheimer’s symptom onset from a blood test: evaluating a prognostic claim}}, journal = {medRxiv}, year = {2026}, doi = {10.64898/2026.03.26.26349230}, url = {https://doi.org/10.64898/2026.03.26.26349230} }