% alzhub.org library filter % Source: https://alzhub.org/research?category=biomarkers % 500 entries, in the order the page lists them. Built from alzhub.org's own records. % 1 entries have no readable author in the source record and carry no author field. @article{yaari2025-40955720, author = {Yaari, Roy and Holdridge, Karen C and Williamson, Melissa and Wessels, Alette M and Shcherbinin, Sergey and Kotari, Vikas and Reiman, Eric M and Tariot, Pierre N and others}, title = {{Donanemab in preclinical Alzheimer's disease: Screening and baseline data from TRAILBLAZER-ALZ 3}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2025}, doi = {10.1002/alz.70662}, pmid = {40955720}, url = {https://doi.org/10.1002/alz.70662} } @article{mielke2026-42509652, author = {Mielke, Michelle M and Gaussoin, Sarah A and Casanova, Ramon and Latham, Lauren A and Manson, JoAnn E and Mouton, Charles P and Ng, Ted K S and Rapp, Stephen R and others}, title = {{Alzheimer's blood-based biomarkers, incident dementia, and interactions with age, APOE status, and hormone therapy}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2026}, doi = {10.1002/alz.71704}, pmid = {42509652}, url = {https://doi.org/10.1002/alz.71704} } @article{ashton2024-38252443, author = {Ashton, N. J. and Brum, W. S. and Di Molfetta, G. and Benedet, A. L. and Arslan, B. and Jonaitis, E. and Langhough, R. E. and Cody, K. and Wilson, R. and Carlsson, C. M. and Vanmechelen, E. and Montoliu-Gaya, L. and others}, title = {{Diagnostic Accuracy of a Plasma Phosphorylated Tau 217 Immunoassay for Alzheimer Disease Pathology}}, journal = {JAMA Neurology}, year = {2024}, doi = {10.1001/jamaneurol.2023.5319}, pmid = {38252443}, url = {https://doi.org/10.1001/jamaneurol.2023.5319} } @article{macfarlane2025-39800452, author = {Macfarlane, S. and Grimmer, T. and Teo, K. and O'Brien, T. J. and Woodward, M. and Grunfeld, J. and Mander, A. and Brodtmann, A. and others}, title = {{Blarcamesine for the treatment of Early Alzheimer's Disease: Results from the ANAVEX2-73-AD-004 Phase IIB/III trial}}, journal = {The journal of prevention of Alzheimer's disease}, year = {2025}, doi = {10.1016/j.tjpad.2024.100016}, pmid = {39800452}, url = {https://doi.org/10.1016/j.tjpad.2024.100016} } @article{chen2026-42318558, author = {Chen, Xiaofen and Huang, Tingting and Shi, Chao and Xu, Shuizhi and Fan, Shuwei}, title = {{Diagnostic performance of plasma p-Tau217, p-Tau181, and p-Tau231 across the Alzheimer's disease continuum: a network meta-analysis}}, journal = {Frontiers in aging neuroscience}, year = {2026}, doi = {10.3389/fnagi.2026.1834591}, pmid = {42318558}, url = {https://doi.org/10.3389/fnagi.2026.1834591} } @article{ljubenkov2021-34559230, author = {Ljubenkov, P. A. and Edwards, L. and Iaccarino, L. and La Joie, R. and Rojas, J. C. and Koestler, M. and Harris, B. and Boeve, B. F. and others}, title = {{Effect of the Histone Deacetylase Inhibitor FRM-0334 on Progranulin Levels in Patients With Progranulin Gene Haploinsufficiency: A Randomized Clinical Trial}}, journal = {JAMA network open}, year = {2021}, doi = {10.1001/jamanetworkopen.2021.25584}, pmid = {34559230}, url = {https://doi.org/10.1001/jamanetworkopen.2021.25584} } @article{salloway2021-34155411, author = {Salloway, S. and Farlow, M. and McDade, E. and Clifford, D. B. and Wang, G. and Llibre-Guerra, J. J. and Hitchcock, J. M. and Mills, S. L. and others}, title = {{A trial of gantenerumab or solanezumab in dominantly inherited Alzheimer's disease}}, journal = {Nature medicine}, year = {2021}, doi = {10.1038/s41591-021-01369-8}, pmid = {34155411}, url = {https://doi.org/10.1038/s41591-021-01369-8} } @article{margraf2022-35237145, author = {Margraf, N. G. and Jensen-Kondering, U. and Weiler, C. and Leypoldt, F. and Maetzler, W. and Philippen, S. and Bartsch, T. and Flüh, C. and others}, title = {{Cerebrospinal Fluid Biomarkers in Cerebral Amyloid Angiopathy: New Data and Quantitative Meta-Analysis}}, journal = {Frontiers in aging neuroscience}, year = {2022}, doi = {10.3389/fnagi.2022.783996}, pmid = {35237145}, url = {https://doi.org/10.3389/fnagi.2022.783996} } @article{ossenkoppele2015-25988463, author = {Ossenkoppele, R. and Jansen, W. J. and Rabinovici, G. D. and Knol, D. L. and van der Flier, W. M. and van Berckel, B. N. and Scheltens, P. and Visser, P. J. and others}, title = {{Prevalence of amyloid PET positivity in dementia syndromes: a meta-analysis}}, journal = {JAMA}, year = {2015}, doi = {10.1001/jama.2015.4669}, pmid = {25988463}, url = {https://doi.org/10.1001/jama.2015.4669} } @article{pontecorvo2022-36251300, author = {Pontecorvo, M. J. and Lu, M. and Burnham, S. C. and Schade, A. E. and Dage, J. L. and Shcherbinin, S. and Collins, E. C. and Sims, JR. and others}, title = {{Association of Donanemab Treatment With Exploratory Plasma Biomarkers in Early Symptomatic Alzheimer Disease: A Secondary Analysis of the TRAILBLAZER-ALZ Randomized Clinical Trial}}, journal = {JAMA neurology}, year = {2022}, doi = {10.1001/jamaneurol.2022.3392}, pmid = {36251300}, url = {https://doi.org/10.1001/jamaneurol.2022.3392} } @article{mcdade2025-40985290, author = {McDade, Eric M and Barthélemy, Nicolas R and Wang, Guoqiao and Li, Yan and Cao, Yuchen and Gordon, Brian and Benzinger, Tammie L S and Clifford, David and others}, title = {{The relationship of soluble tau species with Alzheimer's disease amyloid plaque removal and tau pathology}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2025}, doi = {10.1002/alz.70689}, pmid = {40985290}, url = {https://doi.org/10.1002/alz.70689} } @article{olsson2016-27068280, author = {Olsson, B. and Lautner, R. and Andreasson, U. and Öhrfelt, A. and Portelius, E. and Bjerke, M. and Hölttä, M. and Rosén, C. and others}, title = {{CSF and blood biomarkers for the diagnosis of Alzheimer's disease: a systematic review and meta-analysis}}, journal = {The Lancet. Neurology}, year = {2016}, doi = {10.1016/s1474-4422(16)00070-3}, pmid = {27068280}, url = {https://doi.org/10.1016/s1474-4422(16)00070-3} } @article{mcdade2022-36544184, author = {McDade, E. and Cummings, J. L. and Dhadda, S. and Swanson, C. J. and Reyderman, L. and Kanekiyo, M. and Koyama, A. and Irizarry, M. and others}, title = {{Lecanemab in patients with early Alzheimer's disease: detailed results on biomarker, cognitive, and clinical effects from the randomized and open-label extension of the phase 2 proof-of-concept study}}, journal = {Alzheimer's research \& therapy}, year = {2022}, doi = {10.1186/s13195-022-01124-2}, pmid = {36544184}, url = {https://doi.org/10.1186/s13195-022-01124-2} } @article{wu2023-38017568, author = {Wu, W. and Ji, Y. and Wang, Z. and Wu, X. and Li, J. and Gu, F. and Chen, Z.}, title = {{The FDA-approved anti-amyloid-β monoclonal antibodies for the treatment of Alzheimer's disease: a systematic review and meta-analysis of randomized controlled trials}}, journal = {European journal of medical research}, year = {2023}, doi = {10.1186/s40001-023-01512-w}, pmid = {38017568}, url = {https://doi.org/10.1186/s40001-023-01512-w} } @article{giudici2020-33331917, author = {Giudici, K. V. and de Souto Barreto, P. and Guyonnet, S. and Li, Y. and Bateman, R. J. and Vellas, B. and {MAPT/DSA Group}}, title = {{Assessment of Plasma Amyloid-β42/40 and Cognitive Decline Among Community-Dwelling Older Adults}}, journal = {JAMA network open}, year = {2020}, doi = {10.1001/jamanetworkopen.2020.28634}, pmid = {33331917}, url = {https://doi.org/10.1001/jamanetworkopen.2020.28634} } @article{lohman2024-38851772, author = {Lohman, Trevor and Kapoor, Arunima and Engstrom, Allison C and Shenasa, Fatemah and Alitin, John Paul M and Gaubert, Aimee and Rodgers, Kathleen E and Bradford, David and others}, title = {{Central autonomic network dysfunction and plasma Alzheimer's disease biomarkers in older adults}}, journal = {Alzheimer's research \& therapy}, year = {2024}, doi = {10.1186/s13195-024-01486-9}, pmid = {38851772}, url = {https://doi.org/10.1186/s13195-024-01486-9} } @article{fan2023-37519166, author = {Fan, Zhenyi and Liu, Xiaoxia and Liu, Jie and Chen, Caijing and Zhou, Min}, title = {{Neurofilament Light Chain as a Potential Biomarker in Plasma for Alzheimer's Disease and Mild Cognitive Impairment: A Systematic Review and a Meta-Analysis}}, journal = {Journal of integrative neuroscience}, year = {2023}, doi = {10.31083/j.jin2204085}, pmid = {37519166}, url = {https://doi.org/10.31083/j.jin2204085} } @article{sawyer2026-41824925, author = {Sawyer, Russell P and Blair, Jessica and Judd, Suzanne E and Olson, Nels C and Howard, Virginia J and Armstrong, Nicole D and Long, D Leann and Hyacinth, Hyacinth I and others}, title = {{Circulating Biomarkers of Neurodegeneration and All-Cause and Dementia-Specific Mortality}}, journal = {Neurology}, year = {2026}, doi = {10.1212/wnl.0000000000214752}, pmid = {41824925}, url = {https://doi.org/10.1212/wnl.0000000000214752} } @article{warmenhoven2025-39468767, author = {Warmenhoven, N. and Salvadó, G. and Janelidze, S. and Mattsson-Carlgren, N. and Bali, D. and Orduña Dolado, A. and Kolb, H. and Triana-Baltzer, G. and Barthélemy, N. R. and Schindler, S. E. and Aschenbrenner, A. J. and Raji, C. A. and others}, title = {{A comprehensive head-to-head comparison of key plasma phosphorylated tau 217 biomarker tests}}, journal = {Brain}, year = {2025}, doi = {10.1093/brain/awae346}, pmid = {39468767}, url = {https://doi.org/10.1093/brain/awae346} } @article{ossenkoppele2025-40155777, author = {Ossenkoppele, R. and Salvadó, G. and Janelidze, S. and Pichet Binette, A. and Bali, D. and Karlsson, L. and Palmqvist, S. and Mattsson-Carlgren, N. and Stomrud, E. and Therriault, J. and Rahmouni, N. and Rosa-Neto, P. and others}, title = {{Plasma p-tau217 and tau-PET predict future cognitive decline among cognitively unimpaired individuals: implications for clinical trials}}, journal = {Nature Aging}, year = {2025}, doi = {10.1038/s43587-025-00835-z}, pmid = {40155777}, url = {https://doi.org/10.1038/s43587-025-00835-z} } @article{lu2024-39068543, author = {Lu, Y. and Pike, JR. and Chen, J. and Walker, K. A. and Sullivan, K. J. and Thyagarajan, B. and Mielke, M. M. and Lutsey, P. L. and Knopman, D. and Gottesman, R. F. and Sharrett, A. R. and Coresh, J. and others}, title = {{Changes in Alzheimer Disease Blood Biomarkers and Associations With Incident All-Cause Dementia}}, journal = {JAMA}, year = {2024}, doi = {10.1001/jama.2024.6619}, pmid = {39068543}, url = {https://doi.org/10.1001/jama.2024.6619} } @article{mattssoncarlgren2023-36745413, author = {Mattsson-Carlgren, N. and Salvadó, G. and Ashton, N. J. and Tideman, P. and Stomrud, E. and Zetterberg, H. and Ossenkoppele, R. and Betthauser, T. J. and others}, title = {{Prediction of Longitudinal Cognitive Decline in Preclinical Alzheimer Disease Using Plasma Biomarkers}}, journal = {JAMA neurology}, year = {2023}, doi = {10.1001/jamaneurol.2022.5272}, pmid = {36745413}, url = {https://doi.org/10.1001/jamaneurol.2022.5272} } @article{bateman2012-22784036, author = {Bateman, Randall John and Xiong, Chengjie and Benzinger, Tammie L.S. and Fagan, Anne M. and Goate, Alison and Fox, Nick C. and Marcus, Daniel S. and Cairns, Nigel J. and others}, title = {{Clinical and Biomarker Changes in Dominantly Inherited Alzheimer's Disease}}, journal = {New England Journal of Medicine}, year = {2012}, doi = {10.1056/nejmoa1202753}, pmid = {22784036}, url = {https://doi.org/10.1056/nejmoa1202753} } @article{silvarodriguez2026-42483984, author = {Silva-Rodríguez, Jesús and Zhang, Linda and Kleineidam, Luca and López-González, Francisco J and Wagner-Reguero, Sonia and Martínez-Castillo, Minerva and Sogorb-Esteve, Aitana and Guamán-Chulunchana, Michelle E and others}, title = {{Prognostic value of plasma \%p-tau217 in cognitively unimpaired older adults}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2026}, doi = {10.1002/alz.71599}, pmid = {42483984}, url = {https://doi.org/10.1002/alz.71599} } @article{zhu2021-34311152, author = {Zhu, Yongyun and Yang, Baiyuan and Wang, Fang and Liu, Bin and Li, Kelu and Yin, Kangfu and Yin, Wei Fang and Zhou, Chuanbin and others}, title = {{Association between plasma neurofilament light chain levels and cognitive function in patients with Parkinson's disease}}, journal = {Journal of neuroimmunology}, year = {2021}, doi = {10.1016/j.jneuroim.2021.577662}, pmid = {34311152}, url = {https://doi.org/10.1016/j.jneuroim.2021.577662} } @article{huang2026-40877465, author = {Huang, Xin and Han, Xiaolei and Chang, Hongli and Yu, Tianyu and Dong, Yi and Mao, Ming and Ding, Jiahao and Li, Xuewei and others}, title = {{Associations between trajectories of plasma biomarkers for Alzheimer's disease, brain structures, and cognitive function: a prospective cohort study in the UK Biobank}}, journal = {Molecular psychiatry}, year = {2026}, doi = {10.1038/s41380-025-03166-y}, pmid = {40877465}, url = {https://doi.org/10.1038/s41380-025-03166-y} } @article{mitolo2024-39264441, author = {Mitolo, M. and Lombardi, G. and Manca, R. and Nacmias, B. and Venneri, A.}, title = {{Association between blood-based protein biomarkers and brain MRI in the Alzheimer's disease continuum: a systematic review}}, journal = {Journal of neurology}, year = {2024}, doi = {10.1007/s00415-024-12674-w}, pmid = {39264441}, url = {https://doi.org/10.1007/s00415-024-12674-w} } @article{chen2022-35959295, author = {Chen, L. and Niu, X. and Wang, Y. and Lv, S. and Zhou, X. and Yang, Z. and Peng, D.}, title = {{Plasma tau proteins for the diagnosis of mild cognitive impairment and Alzheimer's disease: A systematic review and meta-analysis}}, journal = {Frontiers in aging neuroscience}, year = {2022}, doi = {10.3389/fnagi.2022.942629}, pmid = {35959295}, url = {https://doi.org/10.3389/fnagi.2022.942629} } @article{khalafi2024-519ae6e6, author = {Khalafi, Mohammad and Dartora, William J. and McIntire, Laura Beth J. and Butler, Tracy A. and Wartchow, Krista M. and Hojjati, Seyed Hani and Razlighi, Qolamreza R. and Shirbandi, Kiarash and Zhou, Liangdong and Chen, Kewei and Xi, Ke and Banerjee, Samprit and Foldi, Nancy and Pahlajani, Silky and Glodzik, Lidia and Li, Yi and de Leon, Mony J. and Chiang, Gloria C.}, title = {{Diagnostic accuracy of phosphorylated tau217 in detecting Alzheimer's disease pathology among cognitively impaired and unimpaired: A systematic review and meta-analysis}}, journal = {Alzheimer's \& Dementia}, year = {2024} } @article{brum2023-37653254, author = {Brum, W. S. and Cullen, N. C. and Janelidze, S. and Ashton, N. J. and Zimmer, E. R. and Therriault, J. and Benedet, A. L. and Rahmouni, N. and Tissot, C. and Stevenson, J. and Servaes, S. and Triana-Baltzer, G. and others}, title = {{A two-step workflow based on plasma p-tau217 to screen for amyloid β positivity with further confirmatory testing only in uncertain cases}}, journal = {Nature Aging}, year = {2023}, doi = {10.1038/s43587-023-00471-5}, pmid = {37653254}, url = {https://doi.org/10.1038/s43587-023-00471-5} } @article{mattssoncarlgren2024-38048096, author = {Mattsson-Carlgren, N. and Collij, L. E. and Stomrud, E. and Pichet Binette, A. and Ossenkoppele, R. and Smith, R. and Karlsson, L. and Lantero-Rodriguez, J. and Snellman, A. and Strandberg, O. and Palmqvist, S. and Ashton, N. J. and others}, title = {{Plasma Biomarker Strategy for Selecting Patients With Alzheimer Disease for Antiamyloid Immunotherapies}}, journal = {JAMA Neurology}, year = {2024}, doi = {10.1001/jamaneurol.2023.4596}, pmid = {38048096}, url = {https://doi.org/10.1001/jamaneurol.2023.4596} } @article{palmqvist2020-32722745, author = {Palmqvist, S. and Janelidze, S. and Quiroz, Y. T. and Zetterberg, H. and Lopera, F. and Stomrud, E. and Su, Y. and Chen, Y. and others}, title = {{Discriminative Accuracy of Plasma Phospho-tau217 for Alzheimer Disease vs Other Neurodegenerative Disorders}}, journal = {JAMA}, year = {2020}, doi = {10.1001/jama.2020.12134}, pmid = {32722745}, url = {https://doi.org/10.1001/jama.2020.12134} } @article{hanseeuw2019-31157827, author = {Hanseeuw, B. J. and Betensky, R. A. and Jacobs, H. I. L. and Schultz, A. P. and Sepulcre, J. and Becker, J. A. and Cosio, D. M. O. and Farrell, M. and others}, title = {{Association of Amyloid and Tau With Cognition in Preclinical Alzheimer Disease: A Longitudinal Study}}, journal = {JAMA neurology}, year = {2019}, doi = {10.1001/jamaneurol.2019.1424}, pmid = {31157827}, url = {https://doi.org/10.1001/jamaneurol.2019.1424} } @article{ossenkoppele2021-34180956, author = {Ossenkoppele, R. and Smith, R. and Mattsson-Carlgren, N. and Groot, C. and Leuzy, A. and Strandberg, O. and Palmqvist, S. and Olsson, T. and others}, title = {{Accuracy of Tau Positron Emission Tomography as a Prognostic Marker in Preclinical and Prodromal Alzheimer Disease: A Head-to-Head Comparison Against Amyloid Positron Emission Tomography and Magnetic Resonance Imaging}}, journal = {JAMA neurology}, year = {2021}, doi = {10.1001/jamaneurol.2021.1858}, pmid = {34180956}, url = {https://doi.org/10.1001/jamaneurol.2021.1858} } @article{balogun2025-41273220, author = {Balogun, Wasiu G and Zeng, Xuemei and Triana-Baltzer, Gallen and Saeed, Anum and Aigbogun, Happiness E and Gogola, Alexandra and Lopresti, Brian J and Villemagne, Victor L and others}, title = {{Cross-cohort validation and cutpoint estimation of the Janssen plasma p-tau217+ assay in predominantly cognitively normal community studies}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2025}, doi = {10.1002/alz.70916}, pmid = {41273220}, url = {https://doi.org/10.1002/alz.70916} } @article{cousins2024-38644682, author = {Cousins, Katheryn A Q and Phillips, Jeffrey S and Das, Sandhitsu R and O'Brien, Kyra and Tropea, Thomas F and Chen-Plotkin, Alice and Shaw, Leslie M and Nasrallah, Ilya M and others}, title = {{Pathologic and cognitive correlates of plasma biomarkers in neurodegenerative disease}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2024}, doi = {10.1002/alz.13777}, pmid = {38644682}, url = {https://doi.org/10.1002/alz.13777} } @article{raghavan2025-40566826, author = {Raghavan, Sheelakumari and Graff-Radford, Jonathan and Hofrenning, Ekaterina and Fought, Angela J and Reid, Robert I and Kamykowski, Michael G and Algeciras-Schimnich, Alicia and Windham, B Gwen and others}, title = {{Plasma NfL and GFAP for predicting VCI and related brain changes in community and clinical cohorts}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2025}, doi = {10.1002/alz.70381}, pmid = {40566826}, url = {https://doi.org/10.1002/alz.70381} } @article{ebbesen2023-37341353, author = {Ebbesen, Svend Ubbe and Høgh, Peter and Zibrandtsen, Ivan}, title = {{Plasma Aβ biomarker for early diagnosis and prognosis of Alzheimer's disease - a systematic review}}, journal = {Danish medical journal}, year = {2023}, pmid = {37341353} } @article{therriault2025-1f9fdc81, author = {Therriault, Joseph and Zetterberg, Henrik and Blennow, Kaj and Rosa-Neto, Pedro and others}, title = {{Blood phosphorylated tau for the diagnosis of Alzheimer's disease: a systematic review and meta-analysis}}, journal = {The Lancet Neurology}, year = {2025}, doi = {10.1016/s1474-4422(25)00227-3}, pmid = {40818474}, url = {https://doi.org/10.1016/s1474-4422(25)00227-3} } @article{janelidze2024-39068669, author = {Janelidze, S. and Barthélemy, N. R. and Salvadó, G. and Schindler, S. E. and Palmqvist, S. and Mattsson-Carlgren, N. and Braunstein, J. B. and Ovod, V. and Bollinger, J. G. and He, Y. and Li, Y. and Raji, C. A. and others}, title = {{Plasma Phosphorylated Tau 217 and Aβ42/40 to Predict Early Brain Aβ Accumulation in People Without Cognitive Impairment}}, journal = {JAMA Neurology}, year = {2024}, doi = {10.1001/jamaneurol.2024.2619}, pmid = {39068669}, url = {https://doi.org/10.1001/jamaneurol.2024.2619} } @article{mattsson2019-31009028, author = {Mattsson, N. and Cullen, N. C. and Andreasson, U. and Zetterberg, H. and Blennow, K.}, title = {{Association Between Longitudinal Plasma Neurofilament Light and Neurodegeneration in Patients With Alzheimer Disease}}, journal = {JAMA neurology}, year = {2019}, doi = {10.1001/jamaneurol.2019.0765}, pmid = {31009028}, url = {https://doi.org/10.1001/jamaneurol.2019.0765} } @article{rabinovici2019-30938796, author = {Rabinovici, G. D. and Gatsonis, C. and Apgar, C. and Chaudhary, K. and Gareen, I. and Hanna, L. and Hendrix, J. and Hillner, B. E. and others}, title = {{Association of Amyloid Positron Emission Tomography With Subsequent Change in Clinical Management Among Medicare Beneficiaries With Mild Cognitive Impairment or Dementia}}, journal = {JAMA}, year = {2019}, doi = {10.1001/jama.2019.2000}, pmid = {30938796}, url = {https://doi.org/10.1001/jama.2019.2000} } @article{lu2025-41082199, author = {Lu, M. and Kim, M. J. and Collins, E. C. and Shcherbinin, S. and Ellinwood, A. K. and Yokoi, Y. and Brooks, D. A. and Hansson, O. and others}, title = {{Posttreatment Amyloid Levels and Clinical Outcomes Following Donanemab for Early Symptomatic Alzheimer Disease: A Secondary Analysis of the TRAILBLAZER-ALZ 2 Randomized Clinical Trial}}, journal = {JAMA neurology}, year = {2025}, doi = {10.1001/jamaneurol.2025.3869}, pmid = {41082199}, url = {https://doi.org/10.1001/jamaneurol.2025.3869} } @article{pichetbinette2022-35351181, author = {Pichet Binette, A. and Palmqvist, S. and Bali, D. and Farrar, G. and Buckley, C. J. and Wolk, D. A. and Zetterberg, H. and Blennow, K. and others}, title = {{Combining plasma phospho-tau and accessible measures to evaluate progression to Alzheimer's dementia in mild cognitive impairment patients}}, journal = {Alzheimer's research \& therapy}, year = {2022}, doi = {10.1186/s13195-022-00990-0}, pmid = {35351181}, url = {https://doi.org/10.1186/s13195-022-00990-0} } @article{zhang2018-29142143, author = {Zhang, Y. P. and Lou, Y. and Hu, J. and Miao, R. and Ma, F.}, title = {{DHA supplementation improves cognitive function via enhancing Aβ-mediated autophagy in Chinese elderly with mild cognitive impairment: a randomised placebo-controlled trial}}, journal = {Journal of neurology, neurosurgery, and psychiatry}, year = {2018}, doi = {10.1136/jnnp-2017-316176}, pmid = {29142143}, url = {https://doi.org/10.1136/jnnp-2017-316176} } @article{benussi2025-39776166, author = {Benussi, A. and Huber, H. and Tan, K. and Cantoni, V. and Rivolta, J. and Cotelli, M. S. and Benedet, A. L. and Blennow, K. and others}, title = {{Plasma p-tau217 and neurofilament/p-tau217 ratio in differentiating Alzheimer's disease from syndromes associated with frontotemporal lobar degeneration}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2025}, doi = {10.1002/alz.14482}, pmid = {39776166}, url = {https://doi.org/10.1002/alz.14482} } @article{shin2025-40768095, author = {Shin, D. and Jang, H. and Yoo, H. and Kim, K. and Zetterberg, H. and Blennow, K. and Gonzalez-Ortiz, F. and Ashton, N. J. and others}, title = {{Potential utility of plasma pTau217 for assessing amyloid and tau biomarker profiles}}, journal = {European journal of nuclear medicine and molecular imaging}, year = {2025}, doi = {10.1007/s00259-025-07457-y}, pmid = {40768095}, url = {https://doi.org/10.1007/s00259-025-07457-y} } @article{antonioni2025-39822285, author = {Antonioni, A. and Raho, E. M. and Manzoli, L. and Koch, G. and Flacco, M. E. and Di Lorenzo, F.}, title = {{Blood phosphorylated Tau181 reliably differentiates amyloid-positive from amyloid-negative subjects in the Alzheimer's disease continuum: A systematic review and meta-analysis}}, journal = {Alzheimer's \& dementia (Amsterdam, Netherlands)}, year = {2025}, doi = {10.1002/dad2.70068}, pmid = {39822285}, url = {https://doi.org/10.1002/dad2.70068} } @article{mattsson2017-28346578, author = {Mattsson, N. and Andreasson, U. and Zetterberg, H. and Blennow, K. and {Alzheimer’s Disease Neuroimaging Initiative}}, title = {{Association of Plasma Neurofilament Light With Neurodegeneration in Patients With Alzheimer Disease}}, journal = {JAMA neurology}, year = {2017}, doi = {10.1001/jamaneurol.2016.6117}, pmid = {28346578}, url = {https://doi.org/10.1001/jamaneurol.2016.6117} } @article{benedet2021-34661615, author = {Benedet, A. L. and Milà-Alomà, M. and Vrillon, A. and Ashton, N. J. and Pascoal, T. A. and Lussier, F. and Karikari, T. K. and Hourregue, C. and others}, title = {{Differences Between Plasma and Cerebrospinal Fluid Glial Fibrillary Acidic Protein Levels Across the Alzheimer Disease Continuum}}, journal = {JAMA neurology}, year = {2021}, doi = {10.1001/jamaneurol.2021.3671}, pmid = {34661615}, url = {https://doi.org/10.1001/jamaneurol.2021.3671} } @article{janelidze2021-33165506, author = {Janelidze, S. and Berron, D. and Smith, R. and Strandberg, O. and Proctor, N. K. and Dage, J. L. and Stomrud, E. and Palmqvist, S. and others}, title = {{Associations of Plasma Phospho-Tau217 Levels With Tau Positron Emission Tomography in Early Alzheimer Disease}}, journal = {JAMA neurology}, year = {2021}, doi = {10.1001/jamaneurol.2020.4201}, pmid = {33165506}, url = {https://doi.org/10.1001/jamaneurol.2020.4201} } @article{moscoso2021-33427873, author = {Moscoso, A. and Grothe, M. J. and Ashton, N. J. and Karikari, T. K. and Lantero Rodríguez, J. and Snellman, A. and Suárez-Calvet, M. and Blennow, K. and others}, title = {{Longitudinal Associations of Blood Phosphorylated Tau181 and Neurofilament Light Chain With Neurodegeneration in Alzheimer Disease}}, journal = {JAMA neurology}, year = {2021}, doi = {10.1001/jamaneurol.2020.4986}, pmid = {33427873}, url = {https://doi.org/10.1001/jamaneurol.2020.4986} } @article{raket2026-42273802, author = {Raket, Lars L and Lu, Ming and Evans, Cynthia D and Zimmer, Jennifer A and Sparks, JonDavid and Collins, Emily C and Shcherbinin, Sergey and Wang, Hong and others}, title = {{Donanemab treatment effect by baseline tau burden and disease severity: Observations from the TRAILBLAZER-ALZ 2 trial}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2026}, doi = {10.1002/alz.71577}, pmid = {42273802}, url = {https://doi.org/10.1002/alz.71577} } @article{trares2026-42463545, author = {Trares, Kira and Duman, Deniz and Beyer, Léon and Michaelian, Johannes C and Stocker, Hannah and Holleczek, Bernd and Beyreuther, Konrad and Schöttker, Ben and others}, title = {{Predictive value of plasma p-tau217 for Alzheimer's dementia compared to other blood-based biomarkers}}, journal = {EMBO molecular medicine}, year = {2026}, doi = {10.1038/s44321-026-00483-9}, pmid = {42463545}, url = {https://doi.org/10.1038/s44321-026-00483-9} } @article{liu2022-36348973, author = {Liu, Chunyu and Li, Yi and Nwosu, Adaora and Ang, Ting Fang Alvin and Liu, Yulin and Devine, Sherral and Au, Rhoda and Doraiswamy, P Murali}, title = {{Sex-specific biomarkers in Alzheimer's disease progression: Framingham Heart Study}}, journal = {Alzheimer's \& dementia (Amsterdam, Netherlands)}, year = {2022}, doi = {10.1002/dad2.12369}, pmid = {36348973}, url = {https://doi.org/10.1002/dad2.12369} } @article{preische2019-30664784, author = {Preische, O. and Schultz, S. A. and Apel, A. and Kuhle, J. and Kaeser, S. A. and Barro, C. and Gräber, S. and others}, title = {{Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer's disease}}, journal = {Nature medicine}, year = {2019}, doi = {10.1038/s41591-018-0304-3}, pmid = {30664784}, url = {https://doi.org/10.1038/s41591-018-0304-3} } @article{barthelemy2024-38382645, author = {Barthélemy, N. R. and Salvadó, G. and Schindler, S. E. and He, Y. and Janelidze, S. and Collij, L. E. and Saef, B. and Henson, R. L. and others}, title = {{Highly accurate blood test for Alzheimer's disease is similar or superior to clinical cerebrospinal fluid tests}}, journal = {Nature medicine}, year = {2024}, doi = {10.1038/s41591-024-02869-z}, pmid = {38382645}, url = {https://doi.org/10.1038/s41591-024-02869-z} } @article{wilkins2022-36190710, author = {Wilkins, C. H. and Windon, C. C. and Dilworth-Anderson, P. and Romanoff, J. and Gatsonis, C. and Hanna, L. and Apgar, C. and Gareen, I. F. and others}, title = {{Racial and Ethnic Differences in Amyloid PET Positivity in Individuals With Mild Cognitive Impairment or Dementia: A Secondary Analysis of the Imaging Dementia-Evidence for Amyloid Scanning (IDEAS) Cohort Study}}, journal = {JAMA neurology}, year = {2022}, doi = {10.1001/jamaneurol.2022.3157}, pmid = {36190710}, url = {https://doi.org/10.1001/jamaneurol.2022.3157} } @article{bellaver2021-33952650, author = {Bellaver, B. and Ferrari-Souza, J. P. and Uglione da Ros, L. and Carter, S. F. and Rodriguez-Vieitez, E. and Nordberg, A. and Pellerin, L. and Rosa-Neto, P. and others}, title = {{Astrocyte Biomarkers in Alzheimer Disease: A Systematic Review and Meta-analysis}}, journal = {Neurology}, year = {2021}, doi = {10.1212/wnl.0000000000012109}, pmid = {33952650}, url = {https://doi.org/10.1212/wnl.0000000000012109} } @article{sperling2024-39044488, author = {Sperling, R. A. and Donohue, M. C. and Rissman, R. A. and Johnson, K. A. and Rentz, D. M. and Grill, J. D. and Heidebrink, J. L. and Jenkins, C. and others}, title = {{Amyloid and Tau Prediction of Cognitive and Functional Decline in Unimpaired Older Individuals: Longitudinal Data from the A4 and LEARN Studies}}, journal = {The journal of prevention of Alzheimer's disease}, year = {2024}, doi = {10.14283/jpad.2024.122}, pmid = {39044488}, url = {https://doi.org/10.14283/jpad.2024.122} } @article{wagemann2024-38683602, author = {Wagemann, O. and Liu, H. and Wang, G. and Shi, X. and Bittner, T. and Scelsi, M. A. and Farlow, M. R. and Clifford, D. B. and others}, title = {{Downstream Biomarker Effects of Gantenerumab or Solanezumab in Dominantly Inherited Alzheimer Disease: The DIAN-TU-001 Randomized Clinical Trial}}, journal = {JAMA neurology}, year = {2024}, doi = {10.1001/jamaneurol.2024.0991}, pmid = {38683602}, url = {https://doi.org/10.1001/jamaneurol.2024.0991} } @article{therriault2024-39533113, author = {Therriault, J. and Janelidze, S. and Benedet, A. L. and Ashton, N. J. and Arranz Martínez, J. and Gonzalez-Escalante, A. and Bellaver, B. and Alcolea, D. and others}, title = {{Diagnosis of Alzheimer's disease using plasma biomarkers adjusted to clinical probability}}, journal = {Nature aging}, year = {2024}, doi = {10.1038/s43587-024-00731-y}, pmid = {39533113}, url = {https://doi.org/10.1038/s43587-024-00731-y} } @article{yokoyama2015-26018225, author = {Yokoyama, H. and Okazaki, K. and Imai, D. and Yamashina, Y. and Takeda, R. and Naghavi, N. and Ota, A. and Hirasawa, Y. and others}, title = {{The effect of cognitive-motor dual-task training on cognitive function and plasma amyloid β peptide 42/40 ratio in healthy elderly persons: a randomized controlled trial}}, journal = {BMC geriatrics}, year = {2015}, doi = {10.1186/s12877-015-0058-4}, pmid = {26018225}, url = {https://doi.org/10.1186/s12877-015-0058-4} } @article{therriault2021-34222875, author = {Therriault, J. and Benedet, A. L. and Pascoal, T. A. and Lussier, F. Z. and Tissot, C. and Karikari, T. K. and Ashton, N. J. and Chamoun, M. and others}, title = {{Association of plasma P-tau181 with memory decline in non-demented adults}}, journal = {Brain communications}, year = {2021}, doi = {10.1093/braincomms/fcab136}, pmid = {34222875}, url = {https://doi.org/10.1093/braincomms/fcab136} } @article{lanterorodriguez2024-38365825, author = {Lantero-Rodriguez, J. and Salvadó, G. and Snellman, A. and Montoliu-Gaya, L. and Brum, W. S. and Benedet, A. L. and Mattsson-Carlgren, N. and Tideman, P. and others}, title = {{Plasma N-terminal containing tau fragments (NTA-tau): a biomarker of tau deposition in Alzheimer's Disease}}, journal = {Molecular neurodegeneration}, year = {2024}, doi = {10.1186/s13024-024-00707-x}, pmid = {38365825}, url = {https://doi.org/10.1186/s13024-024-00707-x} } @article{howe2024-38971815, author = {Howe, M. D. and Britton, K. J. and Joyce, H. E. and Menard, W. and Emrani, S. and Kunicki, Z. J. and Faust, M. A. and Dawson, B. C. and others}, title = {{Clinical application of plasma P-tau217 to assess eligibility for amyloid-lowering immunotherapy in memory clinic patients with early Alzheimer's disease}}, journal = {Alzheimer's research \& therapy}, year = {2024}, doi = {10.1186/s13195-024-01521-9}, pmid = {38971815}, url = {https://doi.org/10.1186/s13195-024-01521-9} } @article{devanarayan2025-39575854, author = {Devanarayan, V. and Charil, A. and Horie, K. and Doherty, T. and Llano, D. A. and Andreozzi, E. and Sachdev, P. and Ye, Y. and others}, title = {{Plasma pTau217 ratio predicts continuous regional brain tau accumulation in amyloid-positive early Alzheimer's disease}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2025}, doi = {10.1002/alz.14411}, pmid = {39575854}, url = {https://doi.org/10.1002/alz.14411} } @article{ferreira2023-36878697, author = {Ferreira, P. C. L. and Ferrari-Souza, J. P. and Tissot, C. and Bellaver, B. and Leffa, D. T. and Lussier, F. and Povala, G. and Therriault, J. and others}, title = {{Potential Utility of Plasma P-Tau and Neurofilament Light Chain as Surrogate Biomarkers for Preventive Clinical Trials}}, journal = {Neurology}, year = {2023}, doi = {10.1212/wnl.0000000000207115}, pmid = {36878697}, url = {https://doi.org/10.1212/wnl.0000000000207115} } @article{altomare2023-37155177, author = {Altomare, D. and Barkhof, F. and Caprioglio, C. and Collij, L. E. and Scheltens, P. and Lopes Alves, I. and Bouwman, F. and Berkhof, J. and others}, title = {{Clinical Effect of Early vs Late Amyloid Positron Emission Tomography in Memory Clinic Patients: The AMYPAD-DPMS Randomized Clinical Trial}}, journal = {JAMA neurology}, year = {2023}, doi = {10.1001/jamaneurol.2023.0997}, pmid = {37155177}, url = {https://doi.org/10.1001/jamaneurol.2023.0997} } @article{mielke2025-39913137, author = {Mielke, M. M. and Evans, J. K. and Neiberg, R. H. and Molina-Henry, D. P. and Marcovina, S. M. and Johnson, K. C. and Carmichael, O. T. and Rapp, SR. and others}, title = {{Alzheimer Disease Blood Biomarkers and Cognition Among Individuals With Diabetes and Overweight or Obesity}}, journal = {JAMA network open}, year = {2025}, doi = {10.1001/jamanetworkopen.2024.58149}, pmid = {39913137}, url = {https://doi.org/10.1001/jamanetworkopen.2024.58149} } @article{woo2025-41451854, author = {Woo, Marcel S and Macedo, Arthur C and Hosseini, Seyyed Ali and Therriault, Joseph and Wang, Yi-Ting and Rahmouni, Nesrine and Aumont, Étienne and Servaes, Stijn and others}, title = {{APOE ɛ4 carriership determines a faster plasma p-tau217 progression in Aβ-positive individuals}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2025}, doi = {10.1002/alz.71048}, pmid = {41451854}, url = {https://doi.org/10.1002/alz.71048} } @article{kang2026-42535277, author = {Kang, Sung Hoon and Park, Yu Jeong and Lee, Seungyun and Kang, Jimin and Lee, Seongin and Lee, Eun Seong and Jung, Hye Na and Ryoo, Inseon and others}, title = {{Heterogeneity in plasma p-tau217 response and its association with cognitive trajectories under lecanemab treatment}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2026}, doi = {10.1002/alz.71705}, pmid = {42535277}, url = {https://doi.org/10.1002/alz.71705} } @article{kim2026-41913058, author = {Kim, Hairin and Soberanes, Daniel and Jutten, Roos J and Dubbelman, Mark A and Yang, Hyun-Sik and Marshall, Gad A and Johnson, Keith A and Betensky, Rebecca A and others}, title = {{Combining p-tau217 and digital cognitive testing to predict cognitive decline}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2026}, doi = {10.1002/alz.71328}, pmid = {41913058}, url = {https://doi.org/10.1002/alz.71328} } @article{vonarnim2026-42518233, author = {von Arnim, Christine A F and Sadlonova, Monika and Derad, Carlotta and Hohberg, Maike and Celano, Christopher M and Günther, Irina and Titsch, Tobias and Krasiuk, Iryna and others}, title = {{Plasma Amyloid-β 1-40 and Postoperative Delirium After Cardiac Surgery}}, journal = {JAMA network open}, year = {2026}, doi = {10.1001/jamanetworkopen.2026.25730}, pmid = {42518233}, url = {https://doi.org/10.1001/jamanetworkopen.2026.25730} } @article{leuzy2023-36681387, author = {Leuzy, Antoine and Mattsson-Carlgren, Niklas and Cullen, Nicholas C and Stomrud, Erik and Palmqvist, Sebastian and La Joie, Renaud and Iaccarino, Leonardo and Zetterberg, Henrik and others}, title = {{Robustness of CSF Aβ42/40 and Aβ42/P-tau181 measured using fully automated immunoassays to detect AD-related outcomes}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2023}, doi = {10.1002/alz.12897}, pmid = {36681387}, url = {https://doi.org/10.1002/alz.12897} } @article{mattssoncarlgren2026-41864233, author = {Mattsson-Carlgren, Niklas and Palmqvist, Sebastian and Horie, Kanta and Barthélemy, Nicolas and Salvadó, Gemma and Binette, Alexa Pichet and Tideman, Pontus and Morris, John C and others}, title = {{Integration of plasma eMTBR-tau243 and p-tau217 in the diagnosis and stratification of Alzheimer's disease: a prospective cohort study}}, journal = {The Lancet. Neurology}, year = {2026}, doi = {10.1016/S1474-4422(26)00029-3}, pmid = {41864233}, url = {https://doi.org/10.1016/S1474-4422(26)00029-3} } @article{salvado2025-40952756, author = {Salvadó, G. and Janelidze, S. and Bali, D. and Dolado, A. O. and Therriault, J. and Brum, W. S. and Pichet Binette, A. and Stomrud, E. and Mattsson-Carlgren, N. and Palmqvist, S. and Coomans, E. M. and Teunissen, C. E. and others}, title = {{Plasma Phosphorylated Tau 217 to Identify Preclinical Alzheimer Disease}}, journal = {JAMA Neurology}, year = {2025}, doi = {10.1001/jamaneurol.2025.3217}, pmid = {40952756}, url = {https://doi.org/10.1001/jamaneurol.2025.3217} } @article{cronje2023-37392405, author = {Cronjé, H. T. and Liu, X. and Odden, M. C. and Moseholm, K. F. and Seshadri, S. and Satizabal, C. L. and Lopez, O. L. and Bis, J. C. and Djoussé, L. and Fohner, A. E. and Psaty, B. M. and Tracy, R. P. and others}, title = {{Serum NfL and GFAP are associated with incident dementia and dementia mortality in older adults: The cardiovascular health study}}, journal = {Alzheimer's \& Dementia}, year = {2023}, doi = {10.1002/alz.13367}, pmid = {37392405}, url = {https://doi.org/10.1002/alz.13367} } @article{palmqvist2024-39068545, author = {Palmqvist, S. and Tideman, P. and Mattsson-Carlgren, N. and Schindler, S. E. and Smith, R. and Ossenkoppele, R. and Calling, S. and West, T. and others}, title = {{Blood Biomarkers to Detect Alzheimer Disease in Primary Care and Secondary Care}}, journal = {JAMA}, year = {2024}, doi = {10.1001/jama.2024.13855}, pmid = {39068545}, url = {https://doi.org/10.1001/jama.2024.13855} } @article{palmqvist2015-26354982, author = {Palmqvist, S. and Zetterberg, H. and Mattsson, N. and Johansson, P. and {Alzheimer's Disease Neuroimaging Initiative} and Minthon, L. and Blennow, K. and Olsson, M. and others}, title = {{Detailed comparison of amyloid PET and CSF biomarkers for identifying early Alzheimer disease}}, journal = {Neurology}, year = {2015}, doi = {10.1212/wnl.0000000000001991}, pmid = {26354982}, url = {https://doi.org/10.1212/wnl.0000000000001991} } @article{pase2019-30830207, author = {Pase, M. P. and Beiser, A. S. and Himali, J. J. and Satizabal, C. L. and Aparicio, H. J. and DeCarli, C. and Chêne, G. and Dufouil, C. and others}, title = {{Assessment of Plasma Total Tau Level as a Predictive Biomarker for Dementia and Related Endophenotypes}}, journal = {JAMA neurology}, year = {2019}, doi = {10.1001/jamaneurol.2018.4666}, pmid = {30830207}, url = {https://doi.org/10.1001/jamaneurol.2018.4666} } @article{leuzy2022-34928318, author = {Leuzy, A. and Smith, R. and Cullen, N. C. and Strandberg, O. and Vogel, J. W. and Binette, A. P. and Borroni, E. and Janelidze, S. and others}, title = {{Biomarker-Based Prediction of Longitudinal Tau Positron Emission Tomography in Alzheimer Disease}}, journal = {JAMA neurology}, year = {2022}, doi = {10.1001/jamaneurol.2021.4654}, pmid = {34928318}, url = {https://doi.org/10.1001/jamaneurol.2021.4654} } @article{benedict2020-31915189, author = {Benedict, C. and Blennow, K. and Zetterberg, H. and Cedernaes, J.}, title = {{Effects of acute sleep loss on diurnal plasma dynamics of CNS health biomarkers in young men}}, journal = {Neurology}, year = {2020}, doi = {10.1212/wnl.0000000000008866}, pmid = {31915189}, url = {https://doi.org/10.1212/wnl.0000000000008866} } @article{ashton2023-36877496, author = {Ashton, N. J. and Moseby-Knappe, M. and Benedet, A. L. and Grötschel, L. and Lantero-Rodriguez, J. and Karikari, T. K. and Hassager, C. and Wise, M. P. and others}, title = {{Alzheimer Disease Blood Biomarkers in Patients With Out-of-Hospital Cardiac Arrest}}, journal = {JAMA neurology}, year = {2023}, doi = {10.1001/jamaneurol.2023.0050}, pmid = {36877496}, url = {https://doi.org/10.1001/jamaneurol.2023.0050} } @article{fleisher2024-38386949, author = {Fleisher, A. S. and Munsie, L. M. and Perahia, D. G. S. and Andersen, S. W. and Higgins, I. A. and Hauck, P. M. and Lo, A. C. and Sims, JR. and others}, title = {{Assessment of Efficacy and Safety of Zagotenemab: Results From PERISCOPE-ALZ, a Phase 2 Study in Early Symptomatic Alzheimer Disease}}, journal = {Neurology}, year = {2024}, doi = {10.1212/wnl.0000000000208061}, pmid = {38386949}, url = {https://doi.org/10.1212/wnl.0000000000208061} } @article{holper2024-38986050, author = {Holper, S. and Loveland, P. and Churilov, L. and Italiano, D. and Watson, R. and Yassi, N.}, title = {{Blood Astrocyte Biomarkers in Alzheimer Disease: A Systematic Review and Meta-Analysis}}, journal = {Neurology}, year = {2024}, doi = {10.1212/wnl.0000000000209537}, pmid = {38986050}, url = {https://doi.org/10.1212/wnl.0000000000209537} } @article{malekahmadi2026-41324928, author = {Malek-Ahmadi, M. and Sharma, S. and Stipho, F. and Denkinger, M. and Singh, A. and Brum, W. S. and Ashton, N. J.}, title = {{Plasma Phosphorylated Tau 217 and Amyloid Burden in Older Adults Without Cognitive Impairment: A Meta-Analysis}}, journal = {JAMA neurology}, year = {2026}, doi = {10.1001/jamaneurol.2025.4721}, pmid = {41324928}, url = {https://doi.org/10.1001/jamaneurol.2025.4721} } @article{matsunaga2015-26402004, author = {Matsunaga, S. and Kishi, T. and Annas, P. and Basun, H. and Hampel, H. and Iwata, N.}, title = {{Lithium as a Treatment for Alzheimer's Disease: A Systematic Review and Meta-Analysis}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2015}, doi = {10.3233/jad-150437}, pmid = {26402004}, url = {https://doi.org/10.3233/jad-150437} } @article{lambert2013-22430674, author = {Lambert, J. C. and Grenier-Boley, B. and Harold, D. and Zelenika, D. and Chouraki, V. and Kamatani, Y. and Sleegers, K. and Ikram, M. A. and others}, title = {{Genome-wide haplotype association study identifies the FRMD4A gene as a risk locus for Alzheimer's disease}}, journal = {Molecular psychiatry}, year = {2013}, doi = {10.1038/mp.2012.14}, pmid = {22430674}, url = {https://doi.org/10.1038/mp.2012.14} } @article{wilson2022-36371232, author = {Wilson, E. N. and Young, C. B. and Ramos Benitez, J. and Swarovski, M. S. and Feinstein, I. and Vandijck, M. and Le Guen, Y. and Kasireddy, N. M. and others}, title = {{Performance of a fully-automated Lumipulse plasma phospho-tau181 assay for Alzheimer's disease}}, journal = {Alzheimer's research \& therapy}, year = {2022}, doi = {10.1186/s13195-022-01116-2}, pmid = {36371232}, url = {https://doi.org/10.1186/s13195-022-01116-2} } @article{ninomiya2020-33129280, author = {Ninomiya, T. and Nakaji, S. and Maeda, T. and Yamada, M. and Mimura, M. and Nakashima, K. and Mori, T. and Takebayashi, M. and others}, title = {{Study design and baseline characteristics of a population-based prospective cohort study of dementia in Japan: the Japan Prospective Studies Collaboration for Aging and Dementia (JPSC-AD)}}, journal = {Environmental health and preventive medicine}, year = {2020}, doi = {10.1186/s12199-020-00903-3}, pmid = {33129280}, url = {https://doi.org/10.1186/s12199-020-00903-3} } @article{milaaloma2025-40539416, author = {Milà-Alomà, M. and Tosun, D. and Schindler, S. E. and Hausle, I. and Petersen, K. K. and Li, Y. and Dage, J. L. and Du-Cuny, L. and others}, title = {{Timing of Changes in Alzheimer's Disease Plasma Biomarkers as Assessed by Amyloid and Tau PET Clocks}}, journal = {Annals of neurology}, year = {2025}, doi = {10.1002/ana.27285}, pmid = {40539416}, url = {https://doi.org/10.1002/ana.27285} } @article{therriault2025-40818474, author = {Therriault, J. and Brum, W. S. and Trudel, L. and Macedo, A. C. and Bitencourt, F. V. and Martins-Pfeifer, C. C. and Nakouzi, M. and Pola, I. and others}, title = {{Blood phosphorylated tau for the diagnosis of Alzheimer's disease: a systematic review and meta-analysis}}, journal = {The Lancet. Neurology}, year = {2025}, doi = {10.1016/s1474-4422(25)00227-3}, pmid = {40818474}, url = {https://doi.org/10.1016/s1474-4422(25)00227-3} } @article{antonioni2025-40047958, author = {Antonioni, A. and Raho, E. M. and Di Lorenzo, F. and Manzoli, L. and Flacco, M. E. and Koch, G.}, title = {{Blood phosphorylated Tau217 distinguishes amyloid-positive from amyloid-negative subjects in the Alzheimer's disease continuum. A systematic review and meta-analysis}}, journal = {Journal of neurology}, year = {2025}, doi = {10.1007/s00415-025-12996-3}, pmid = {40047958}, url = {https://doi.org/10.1007/s00415-025-12996-3} } @article{cicognola2025-39817469, author = {Cicognola, C. and Salvadó, G. and Smith, R. and Palmqvist, S. and Stomrud, E. and Betthauser, T. J. and Johnson, S. C. and Janelidze, S. and others}, title = {{APOE4 impact on soluble and insoluble tau pathology is mostly influenced by amyloid-β}}, journal = {Brain : a journal of neurology}, year = {2025}, doi = {10.1093/brain/awaf016}, pmid = {39817469}, url = {https://doi.org/10.1093/brain/awaf016} } @article{hayek2024-38216727, author = {Hayek, D. and Ziegler, G. and Kleineidam, L. and Brosseron, F. and Nemali, A. and Vockert, N. and Ravichandran, K. A. and Betts, M. J. and others}, title = {{Different inflammatory signatures based on CSF biomarkers relate to preserved or diminished brain structure and cognition}}, journal = {Molecular psychiatry}, year = {2024}, doi = {10.1038/s41380-023-02387-3}, pmid = {38216727}, url = {https://doi.org/10.1038/s41380-023-02387-3} } @article{santos2023-36423207, author = {Santos, F. and Cabreira, V. and Rocha, S. and Massano, J.}, title = {{Blood Biomarkers for the Diagnosis of Neurodegenerative Dementia: A Systematic Review}}, journal = {Journal of geriatric psychiatry and neurology}, year = {2023}, doi = {10.1177/08919887221141651}, pmid = {36423207}, url = {https://doi.org/10.1177/08919887221141651} } @article{li2024-38339929, author = {Li, Z. and Fan, Z. and Zhang, Q.}, title = {{The Associations of Phosphorylated Tau 181 and Tau 231 Levels in Plasma and Cerebrospinal Fluid with Cognitive Function in Alzheimer's Disease: A Systematic Review and Meta-Analysis}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2024}, doi = {10.3233/jad-230799}, pmid = {38339929}, url = {https://doi.org/10.3233/jad-230799} } @article{wang2024-38126555, author = {Wang, X. and Bakulski, K. M. and Karvonen-Gutierrez, C. A. and Park, S. K. and Morgan, D. and Albin, R. L. and Paulson, H. L.}, title = {{Blood-based biomarkers for Alzheimer's disease and cognitive function from mid- to late life}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2024}, doi = {10.1002/alz.13583}, pmid = {38126555}, url = {https://doi.org/10.1002/alz.13583} } @article{perna2023-37951931, author = {Perna, L. and Stocker, H. and Burow, L. and Beyer, L. and Trares, K. and Kurz, C. and Gürsel, S. and Holleczek, B. and others}, title = {{Subjective cognitive complaints and blood biomarkers of neurodegenerative diseases: a longitudinal cohort study}}, journal = {Alzheimer's research \& therapy}, year = {2023}, doi = {10.1186/s13195-023-01341-3}, pmid = {37951931}, url = {https://doi.org/10.1186/s13195-023-01341-3} } @article{forgrave2019-31909174, author = {Forgrave, L. M. and Ma, M. and Best, JR. and DeMarco, M. L.}, title = {{The diagnostic performance of neurofilament light chain in CSF and blood for Alzheimer's disease, frontotemporal dementia, and amyotrophic lateral sclerosis: A systematic review and meta-analysis}}, journal = {Alzheimer's \& dementia (Amsterdam, Netherlands)}, year = {2019}, doi = {10.1016/j.dadm.2019.08.009}, pmid = {31909174}, url = {https://doi.org/10.1016/j.dadm.2019.08.009} } @article{olsson2018-29425372, author = {Olsson, M. and Ärlig, J. and Hedner, J. and Blennow, K. and Zetterberg, H.}, title = {{Sleep deprivation and cerebrospinal fluid biomarkers for Alzheimer's disease}}, journal = {Sleep}, year = {2018}, doi = {10.1093/sleep/zsy025}, pmid = {29425372}, url = {https://doi.org/10.1093/sleep/zsy025} } @article{sun2026-41854616, author = {Sun, Haoqi and Milton, Sasha and Fang, Yi and Taha, Hash Brown and Shiju, Shreya and Thomas, Robert J and Ganglberger, Wolfgang and Pase, Matthew P and others}, title = {{Machine Learning-Based Sleep Electroencephalographic Brain Age Index and Dementia Risk: An Individual Participant Data Meta-Analysis}}, journal = {JAMA network open}, year = {2026}, doi = {10.1001/jamanetworkopen.2026.1521}, pmid = {41854616}, url = {https://doi.org/10.1001/jamanetworkopen.2026.1521} } @article{wang2025-40156286, author = {Wang, J. and Huang, S. and Lan, G. and Lai, Y. J. and Wang, Q. H. and Chen, Y. and Xiao, Z. S. and Chen, X. and Bu, X. L. and Liu, Y. H. and Zeng, F. and Zhang, L. and others}, title = {{Diagnostic accuracy of plasma p-tau217/Aβ42 for Alzheimer's disease in clinical and community cohorts}}, journal = {Alzheimer's \& Dementia}, year = {2025}, doi = {10.1002/alz.70038}, pmid = {40156286}, url = {https://doi.org/10.1002/alz.70038} } @article{sanchezjuan2024-38634687, author = {Sánchez-Juan, P. and Valeriano-Lorenzo, E. and Ruiz-González, A. and Pastor, A. B. and Rodrigo Lara, H. and López-González, F. and Zea-Sevilla, M. A. and Valentí, M. and Frades, B. and Ruiz, P. and Saiz, L. and Burgueño-García, I. and others}, title = {{Serum GFAP levels correlate with astrocyte reactivity, post-mortem brain atrophy and neurofibrillary tangles}}, journal = {Brain}, year = {2024}, doi = {10.1093/brain/awae035}, pmid = {38634687}, url = {https://doi.org/10.1093/brain/awae035} } @article{palmqvist2019-31233127, author = {Palmqvist, S. and Janelidze, S. and Stomrud, E. and Zetterberg, H. and Karl, J. and Zink, K. and Bittner, T. and Mattsson, N. and others}, title = {{Performance of Fully Automated Plasma Assays as Screening Tests for Alzheimer Disease-Related β-Amyloid Status}}, journal = {JAMA neurology}, year = {2019}, doi = {10.1001/jamaneurol.2019.1632}, pmid = {31233127}, url = {https://doi.org/10.1001/jamaneurol.2019.1632} } @article{therriault2023-36508198, author = {Therriault, J. and Vermeiren, M. and Servaes, S. and Tissot, C. and Ashton, N. J. and Benedet, A. L. and Karikari, T. K. and Lantero-Rodriguez, J. and others}, title = {{Association of Phosphorylated Tau Biomarkers With Amyloid Positron Emission Tomography vs Tau Positron Emission Tomography}}, journal = {JAMA neurology}, year = {2023}, doi = {10.1001/jamaneurol.2022.4485}, pmid = {36508198}, url = {https://doi.org/10.1001/jamaneurol.2022.4485} } @article{lane2019-31444142, author = {Lane, C. A. and Barnes, J. and Nicholas, J. M. and Sudre, C. H. and Cash, D. M. and Parker, T. D. and Malone, I. B. and Lu, K. and others}, title = {{Associations between blood pressure across adulthood and late-life brain structure and pathology in the neuroscience substudy of the 1946 British birth cohort (Insight 46): an epidemiological study}}, journal = {The Lancet. Neurology}, year = {2019}, doi = {10.1016/s1474-4422(19)30228-5}, pmid = {31444142}, url = {https://doi.org/10.1016/s1474-4422(19)30228-5} } @article{jack2019-31501889, author = {Jack, C. R. and Wiste, H. J. and Botha, H. and Weigand, S. D. and Therneau, T. M. and Knopman, D. S. and Graff-Radford, J. and Jones, D. T. and others}, title = {{The bivariate distribution of amyloid-β and tau: relationship with established neurocognitive clinical syndromes}}, journal = {Brain : a journal of neurology}, year = {2019}, doi = {10.1093/brain/awz268}, pmid = {31501889}, url = {https://doi.org/10.1093/brain/awz268} } @article{raghavan2020-32568366, author = {Raghavan, N. S. and Dumitrescu, L. and Mormino, E. and Mahoney, E. R. and Lee, A. J. and Gao, Y. and Bilgel, M. and Goldstein, D. and others}, title = {{Association Between Common Variants in RBFOX1, an RNA-Binding Protein, and Brain Amyloidosis in Early and Preclinical Alzheimer Disease}}, journal = {JAMA neurology}, year = {2020}, doi = {10.1001/jamaneurol.2020.1760}, pmid = {32568366}, url = {https://doi.org/10.1001/jamaneurol.2020.1760} } @article{stevensonhoare2023-35383826, author = {Stevenson-Hoare, J. and Heslegrave, A. and Leonenko, G. and Fathalla, D. and Bellou, E. and Luckcuck, L. and Marshall, R. and Sims, R. and others}, title = {{Plasma biomarkers and genetics in the diagnosis and prediction of Alzheimer's disease}}, journal = {Brain : a journal of neurology}, year = {2023}, doi = {10.1093/brain/awac128}, pmid = {35383826}, url = {https://doi.org/10.1093/brain/awac128} } @article{jonaitis2023-37013174, author = {Jonaitis, E. M. and Janelidze, S. and Cody, K. A. and Langhough, R. and Du, L. and Chin, N. A. and Mattsson-Carlgren, N. and Hogan, K. J. and others}, title = {{Plasma phosphorylated tau 217 in preclinical Alzheimer's disease}}, journal = {Brain communications}, year = {2023}, doi = {10.1093/braincomms/fcad057}, pmid = {37013174}, url = {https://doi.org/10.1093/braincomms/fcad057} } @article{oconnor2021-32665603, author = {O'Connor, A. and Karikari, T. K. and Poole, T. and Ashton, N. J. and Lantero Rodriguez, J. and Khatun, A. and Swift, I. and Heslegrave, A. J. and others}, title = {{Plasma phospho-tau181 in presymptomatic and symptomatic familial Alzheimer's disease: a longitudinal cohort study}}, journal = {Molecular psychiatry}, year = {2021}, doi = {10.1038/s41380-020-0838-x}, pmid = {32665603}, url = {https://doi.org/10.1038/s41380-020-0838-x} } @article{kim2023-37174709, author = {Kim, K. Y. and Shin, K. Y. and Chang, K. A.}, title = {{GFAP as a Potential Biomarker for Alzheimer's Disease: A Systematic Review and Meta-Analysis}}, journal = {Cells}, year = {2023}, doi = {10.3390/cells12091309}, pmid = {37174709}, url = {https://doi.org/10.3390/cells12091309} } @article{pereira2021-34077494, author = {Pereira, J. B. and Janelidze, S. and Stomrud, E. and Palmqvist, S. and van Westen, D. and Dage, J. L. and Mattsson-Carlgren, N. and Hansson, O.}, title = {{Plasma markers predict changes in amyloid, tau, atrophy and cognition in non-demented subjects}}, journal = {Brain : a journal of neurology}, year = {2021}, doi = {10.1093/brain/awab163}, pmid = {34077494}, url = {https://doi.org/10.1093/brain/awab163} } @article{billette2022-35995589, author = {Billette, O. V. and Ziegler, G. and Aruci, M. and Schütze, H. and Kizilirmak, J. M. and Richter, A. and Altenstein, S. and Bartels, C. and others}, title = {{Novelty-Related fMRI Responses of Precuneus and Medial Temporal Regions in Individuals at Risk for Alzheimer Disease}}, journal = {Neurology}, year = {2022}, doi = {10.1212/wnl.0000000000200667}, pmid = {35995589}, url = {https://doi.org/10.1212/wnl.0000000000200667} } @article{ingala2021-34617016, author = {Ingala, S. and Tomassen, J. and Collij, L. E. and Prent, N. and van 't Ent, D. and Ten Kate, M. and Konijnenberg, E. and Yaqub, M. and others}, title = {{Amyloid-driven disruption of default mode network connectivity in cognitively healthy individuals}}, journal = {Brain communications}, year = {2021}, doi = {10.1093/braincomms/fcab201}, pmid = {34617016}, url = {https://doi.org/10.1093/braincomms/fcab201} } @article{liu2022-35535875, author = {Liu, W. L. and Lin, H. W. and Lin, M. R. and Yu, Y. and Liu, H. H. and Dai, Y. L. and Chen, L. W. and Jia, W. W. and others}, title = {{Emerging blood exosome-based biomarkers for preclinical and clinical Alzheimer's disease: a meta-analysis and systematic review}}, journal = {Neural regeneration research}, year = {2022}, doi = {10.4103/1673-5374.335832}, pmid = {35535875}, url = {https://doi.org/10.4103/1673-5374.335832} } @article{nous2021-33622399, author = {Nous, A. and Engelborghs, S. and Smolders, I.}, title = {{Melatonin levels in the Alzheimer's disease continuum: a systematic review}}, journal = {Alzheimer's research \& therapy}, year = {2021}, doi = {10.1186/s13195-021-00788-6}, pmid = {33622399}, url = {https://doi.org/10.1186/s13195-021-00788-6} } @article{johansson2023-36626935, author = {Johansson, C. and Thordardottir, S. and Laffita-Mesa, J. and Rodriguez-Vieitez, E. and Zetterberg, H. and Blennow, K. and Graff, C.}, title = {{Plasma biomarker profiles in autosomal dominant Alzheimer's disease}}, journal = {Brain : a journal of neurology}, year = {2023}, doi = {10.1093/brain/awac399}, pmid = {36626935}, url = {https://doi.org/10.1093/brain/awac399} } @article{study2026-42163294, title = {{Plasma p-tau217, p-tau181, and Aβ42 predict amyloid PET positivity in cognitively unimpaired adults}}, journal = {Alzheimer's research \& therapy}, year = {2026}, doi = {10.1186/s13195-026-02080-x}, pmid = {42163294}, url = {https://doi.org/10.1186/s13195-026-02080-x} } @article{jiang2026-42601653, author = {Jiang, Mingxing and Lan, Guoyu and Zhu, Jiayi and Zhang, Laihong and Li, Anqi and He, Zhengbo and Zhu, Yalin and Zhou, Xin and others}, title = {{Cross-Sectional and Longitudinal Diagnostic Performance of Plasma p-tau217 and p-tau217/Aβ42 in Alzheimer's Disease}}, journal = {Annals of neurology}, year = {2026}, doi = {10.1002/ana.78322}, pmid = {42601653}, url = {https://doi.org/10.1002/ana.78322} } @article{tropea2026-41848292, author = {Tropea, Thomas F and Stevenson, Patricia Aldea and Flitter, Matthew and Meehan, David and Morris, Amanda and Lu, Ming and Iaccarino, Leonardo and Collins, Emily C and others}, title = {{Association between Plasma P-tau217 and Alzheimer's Copathology and Cognitive Decline in Parkinson's Disease}}, journal = {Annals of neurology}, year = {2026}, doi = {10.1002/ana.78201}, pmid = {41848292}, url = {https://doi.org/10.1002/ana.78201} } @article{gibson2025-39732510, author = {Gibson, Lucy L and Gonzalez, Maria C and Ashton, Nicholas J and Tovar-Rios, Diego and Blanc, Frédéric and Pilotto, Andrea and Lemstra, Afina and Paquet, Claire and others}, title = {{Plasma phosphorylated tau and neuropsychiatric symptoms in dementia with Lewy bodies}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2025}, doi = {10.1002/alz.14434}, pmid = {39732510}, url = {https://doi.org/10.1002/alz.14434} } @article{xu2025-41307156, author = {Xu, Yuexuan and Qiao, Min and Gunasekaran, Tamil I and Gu, Yian and Reyes-Dumeyer, Dolly and Piriz, Angel and Sanchez, Danurys and Soriano, Belisa and others}, title = {{Polygenic scores of Core 1 Alzheimer's disease biomarkers predict early cognitive and pathological change}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2025}, doi = {10.1002/alz.70937}, pmid = {41307156}, url = {https://doi.org/10.1002/alz.70937} } @article{xiao2023-38145191, author = {Xiao, Zhenxu and Wu, Wanqing and Ma, Xiaoxi and Wu, Jie and Liang, Xiaoniu and Zhou, Xiaowen and Cao, Yang and Zhao, Qianhua and others}, title = {{Plasma p-tau217, p-tau181, and NfL as early indicators of dementia risk in a community cohort: The Shanghai Aging Study}}, journal = {Alzheimer's \& dementia (Amsterdam, Netherlands)}, year = {2023}, doi = {10.1002/dad2.12514}, pmid = {38145191}, url = {https://doi.org/10.1002/dad2.12514} } @article{huang2025-40927740, author = {Huang, Qi and Jonaitis, Erin M and Studer, Rachel L and Wilson, Rachael and Reyes, Ramiro Eduardo Rea and Zetterberg, Henrik and Du, Lianlian and Hermann, Bruce P and others}, title = {{Preclinical dementia rating scores are associated with plasma phosphorylated tau-217}}, journal = {Alzheimer's \& dementia (Amsterdam, Netherlands)}, year = {2025}, doi = {10.1002/dad2.70179}, pmid = {40927740}, url = {https://doi.org/10.1002/dad2.70179} } @article{rabl2024-39054505, author = {Rabl, Miriam and Zullo, Leonardo and Lewczuk, Piotr and Kornhuber, Johannes and Karikari, Thomas K and Blennow, Kaj and Zetterberg, Henrik and Bavato, Francesco and others}, title = {{Plasma neurofilament light, glial fibrillary acid protein, and phosphorylated tau 181 as biomarkers for neuropsychiatric symptoms and related clinical disease progression}}, journal = {Alzheimer's research \& therapy}, year = {2024}, doi = {10.1186/s13195-024-01526-4}, pmid = {39054505}, url = {https://doi.org/10.1186/s13195-024-01526-4} } @article{schworer2024-38623384, author = {Schworer, Emily K and Handen, Benjamin L and Petersen, Melissa and O'Bryant, Sid and Peven, Jamie C and Tudorascu, Dana L and Lee, Laisze and Krinsky-McHale, Sharon J and others}, title = {{Cognitive and functional performance and plasma biomarkers of early Alzheimer's disease in Down syndrome}}, journal = {Alzheimer's \& dementia (Amsterdam, Netherlands)}, year = {2024}, doi = {10.1002/dad2.12582}, pmid = {38623384}, url = {https://doi.org/10.1002/dad2.12582} } @article{zhou2020-32775599, author = {Zhou, Xiaopu and Chen, Yu and Ip, Fanny C F and Lai, Nicole C H and Li, Yolanda Y T and Jiang, Yuanbing and Zhong, Huan and Chen, Yuewen and others}, title = {{Genetic and polygenic risk score analysis for Alzheimer's disease in the Chinese population}}, journal = {Alzheimer's \& dementia (Amsterdam, Netherlands)}, year = {2020}, doi = {10.1002/dad2.12074}, pmid = {32775599}, url = {https://doi.org/10.1002/dad2.12074} } @article{montoliugaya2025-40847200, author = {Montoliu-Gaya, Laia and Salvadó, Gemma and Therriault, Joseph and Nilsson, Johanna and Janelidze, Shorena and Weiner, Sophia and Ashton, Nicholas J and Benedet, Andrea L and others}, title = {{Plasma tau biomarkers for biological staging of Alzheimer's disease}}, journal = {Nature aging}, year = {2025}, doi = {10.1038/s43587-025-00951-w}, pmid = {40847200}, url = {https://doi.org/10.1038/s43587-025-00951-w} } @article{therriault2021-cf62d2ac, author = {Therriault, Joseph and Benedet, Andrea L and Pascoal, Tharick A and Lussier, Firoza Z and Tissot, Cecile and Karikari, Thomas K and Ashton, Nicholas J and Chamoun, Mira and others}, title = {{Association of plasma P-tau181 with memory decline in non-demented adults}}, journal = {Brain Communications}, year = {2021}, doi = {10.1093/braincomms/fcab136}, url = {https://doi.org/10.1093/braincomms/fcab136} } @article{ding2021-33712071, author = {Ding, X. and Zhang, S. and Jiang, L. and Wang, L. and Li, T. and Lei, P.}, title = {{Ultrasensitive assays for detection of plasma tau and phosphorylated tau 181 in Alzheimer's disease: a systematic review and meta-analysis}}, journal = {Translational neurodegeneration}, year = {2021}, doi = {10.1186/s40035-021-00234-5}, pmid = {33712071}, url = {https://doi.org/10.1186/s40035-021-00234-5} } @article{groot2023-36084009, author = {Groot, C. and Smith, R. and Stomrud, E. and Binette, A. P. and Leuzy, A. and Wuestefeld, A. and Wisse, L. E. M. and Palmqvist, S. and others}, title = {{Phospho-tau with subthreshold tau-PET predicts increased tau accumulation rates in amyloid-positive individuals}}, journal = {Brain : a journal of neurology}, year = {2023}, doi = {10.1093/brain/awac329}, pmid = {36084009}, url = {https://doi.org/10.1093/brain/awac329} } @article{zabalafindlay2023-37190093, author = {Zabala-Findlay, A. and Penny, L. K. and Lofthouse, R. A. and Porter, A. J. and Palliyil, S. and Harrington, C. R. and Wischik, C. M. and Arastoo, M.}, title = {{Utility of Blood-Based Tau Biomarkers for Mild Cognitive Impairment and Alzheimer's Disease: Systematic Review and Meta-Analysis}}, journal = {Cells}, year = {2023}, doi = {10.3390/cells12081184}, pmid = {37190093}, url = {https://doi.org/10.3390/cells12081184} } @article{paez2025-39878233, author = {Páez, A. and Gillman, S. O. and Dogaheh, S. B. and Carnes, A. and Dakterzada, F. and Barbé, F. and Dang-Vu, T. T. and Ripoll, G. P.}, title = {{Sleep spindles and slow oscillations predict cognition and biomarkers of neurodegeneration in mild to moderate Alzheimer's disease}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2025}, doi = {10.1002/alz.14424}, pmid = {39878233}, url = {https://doi.org/10.1002/alz.14424} } @article{tsiknia2022-36324151, author = {Tsiknia, A. A. and Sundermann, E. E. and Reas, E. T. and Edland, S. D. and Brewer, J. B. and Galasko, D. and Banks, S. J. and {Alzheimer’s Disease Neuroimaging Initiative}}, title = {{Sex differences in Alzheimer's disease: plasma MMP-9 and markers of disease severity}}, journal = {Alzheimer's research \& therapy}, year = {2022}, doi = {10.1186/s13195-022-01106-4}, pmid = {36324151}, url = {https://doi.org/10.1186/s13195-022-01106-4} } @article{thomas2021-34692978, author = {Thomas, K. R. and Bangen, K. J. and Edmonds, E. C. and Weigand, A. J. and Walker, K. S. and Bondi, M. W. and Galasko, D. R. and {Alzheimer's Disease Neuroimaging Initiative}}, title = {{Objective subtle cognitive decline and plasma phosphorylated tau181: Early markers of Alzheimer's disease-related declines}}, journal = {Alzheimer's \& dementia (Amsterdam, Netherlands)}, year = {2021}, doi = {10.1002/dad2.12238}, pmid = {34692978}, url = {https://doi.org/10.1002/dad2.12238} } @article{xiong2024-37438991, author = {Xiong, X. and He, H. and Ye, Q. and Qian, S. and Zhou, S. and Feng, F. and Fang, E. F. and Xie, C.}, title = {{Alzheimer's disease diagnostic accuracy by fluid and neuroimaging ATN framework}}, journal = {CNS neuroscience \& therapeutics}, year = {2024}, doi = {10.1111/cns.14357}, pmid = {37438991}, url = {https://doi.org/10.1111/cns.14357} } @article{sewell2024-38488949, author = {Sewell, K. R. and Rainey-Smith, SR. and Pedrini, S. and Peiffer, J. J. and Sohrabi, H. R. and Taddei, K. and Markovic, S. J. and Martins, R. N. and others}, title = {{The impact of exercise on blood-based biomarkers of Alzheimer's disease in cognitively unimpaired older adults}}, journal = {GeroScience}, year = {2024}, doi = {10.1007/s11357-024-01130-2}, pmid = {38488949}, url = {https://doi.org/10.1007/s11357-024-01130-2} } @article{demeyer2024-39051027, author = {De Meyer, S. and Schaeverbeke, J. M. and Luckett, E. S. and Reinartz, M. and Blujdea, E. R. and Cleynen, I. and Dupont, P. and Van Laere, K. and others}, title = {{Plasma pTau181 and pTau217 predict asymptomatic amyloid accumulation equally well as amyloid PET}}, journal = {Brain communications}, year = {2024}, doi = {10.1093/braincomms/fcae162}, pmid = {39051027}, url = {https://doi.org/10.1093/braincomms/fcae162} } @article{ornago2025-40414227, author = {Ornago, A. M. and Pinardi, E. and Grande, G. and Valletta, M. and Calderón-Larrañaga, A. and Andersson, S. and Calvani, R. and Picca, A. and others}, title = {{Blood biomarkers of Alzheimer's disease and 12-year muscle strength trajectories in community-dwelling older adults: a cohort study}}, journal = {The lancet. Healthy longevity}, year = {2025}, doi = {10.1016/j.lanhl.2025.100715}, pmid = {40414227}, url = {https://doi.org/10.1016/j.lanhl.2025.100715} } @article{petersen2026-41714746, author = {Petersen, Kellen K and Milà-Alomà, Marta and Li, Yan and Du, Lianlian and Xiong, Chengjie and Tosun, Duygu and Saef, Benjamin and Saad, Ziad S and others}, title = {{Predicting onset of symptomatic Alzheimer's disease with plasma p-tau217 clocks}}, journal = {Nature medicine}, year = {2026}, doi = {10.1038/s41591-026-04206-y}, pmid = {41714746}, url = {https://doi.org/10.1038/s41591-026-04206-y} } @article{yakoub2025-40008832, author = {Yakoub, Y. and Gonzalez-Ortiz, F. and Ashton, N. J. and Déry, C. and Strikwerda-Brown, C. and St-Onge, F. and Ourry, V. and Schöll, M. and Geddes, M. R. and Ducharme, S. and Montembeault, M. and Rosa-Neto, P. and others}, title = {{Plasma p-tau217 identifies cognitively normal older adults who will develop cognitive impairment in a 10-year window}}, journal = {Alzheimer's \& Dementia}, year = {2025}, doi = {10.1002/alz.14537}, pmid = {40008832}, url = {https://doi.org/10.1002/alz.14537} } @article{jack2019-31211344, author = {Jack, C. R. and Wiste, H. J. and Therneau, T. M. and Weigand, S. D. and Knopman, D. S. and Mielke, M. M. and Lowe, V. J. and Vemuri, P. and others}, title = {{Associations of Amyloid, Tau, and Neurodegeneration Biomarker Profiles With Rates of Memory Decline Among Individuals Without Dementia}}, journal = {JAMA}, year = {2019}, doi = {10.1001/jama.2019.7437}, pmid = {31211344}, url = {https://doi.org/10.1001/jama.2019.7437} } @article{jansen2022-35099509, author = {Jansen, W. J. and Janssen, O. and Tijms, B. M. and Vos, S. J. B. and Ossenkoppele, R. and Visser, P. J. and {Amyloid Biomarker Study Group} and Aarsland, D. and others}, title = {{Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum}}, journal = {JAMA neurology}, year = {2022}, doi = {10.1001/jamaneurol.2021.5216}, pmid = {35099509}, url = {https://doi.org/10.1001/jamaneurol.2021.5216} } @article{jack2019-31305929, author = {Jack, C. R. and Therneau, T. M. and Weigand, S. D. and Wiste, H. J. and Knopman, D. S. and Vemuri, P. and Lowe, V. J. and Mielke, M. M. and others}, title = {{Prevalence of Biologically vs Clinically Defined Alzheimer Spectrum Entities Using the National Institute on Aging-Alzheimer's Association Research Framework}}, journal = {JAMA neurology}, year = {2019}, doi = {10.1001/jamaneurol.2019.1971}, pmid = {31305929}, url = {https://doi.org/10.1001/jamaneurol.2019.1971} } @article{hu2022-35446396, author = {Hu, Y. and Kirmess, K. M. and Meyer, M. R. and Rabinovici, G. D. and Gatsonis, C. and Siegel, B. A. and Whitmer, R. A. and Apgar, C. and others}, title = {{Assessment of a Plasma Amyloid Probability Score to Estimate Amyloid Positron Emission Tomography Findings Among Adults With Cognitive Impairment}}, journal = {JAMA network open}, year = {2022}, doi = {10.1001/jamanetworkopen.2022.8392}, pmid = {35446396}, url = {https://doi.org/10.1001/jamanetworkopen.2022.8392} } @article{stocker2023-36692879, author = {Stocker, H. and Beyer, L. and Trares, K. and Perna, L. and Rujescu, D. and Holleczek, B. and Beyreuther, K. and Gerwert, K. and others}, title = {{Association of Kidney Function With Development of Alzheimer Disease and Other Dementias and Dementia-Related Blood Biomarkers}}, journal = {JAMA network open}, year = {2023}, doi = {10.1001/jamanetworkopen.2022.52387}, pmid = {36692879}, url = {https://doi.org/10.1001/jamanetworkopen.2022.52387} } @article{planche2023-36261295, author = {Planche, V. and Bouteloup, V. and Pellegrin, I. and Mangin, J. F. and Dubois, B. and Ousset, P. J. and Pasquier, F. and Blanc, F. and others}, title = {{Validity and Performance of Blood Biomarkers for Alzheimer Disease to Predict Dementia Risk in a Large Clinic-Based Cohort}}, journal = {Neurology}, year = {2023}, doi = {10.1212/wnl.0000000000201479}, pmid = {36261295}, url = {https://doi.org/10.1212/wnl.0000000000201479} } @article{bouteloup2025-40181683, author = {Bouteloup, V. and Villain, N. and Vidal, J. S. and Gonzalez-Ortiz, F. and Yuksekel, I. and Santos, C. and Schraen-Maschken, S. and Pellegrin, I. and others}, title = {{Cognitive Phenotyping and Interpretation of Alzheimer Blood Biomarkers}}, journal = {JAMA neurology}, year = {2025}, doi = {10.1001/jamaneurol.2025.0142}, pmid = {40181683}, url = {https://doi.org/10.1001/jamaneurol.2025.0142} } @article{sanchez2025-40063856, author = {Sanchez, E. and Coughlan, G. T. and Wilkinson, T. and Ramirez, J. and Mirza, S. S. and Baril, A. A. and Dilliott, A. A. and Frank, A. and others}, title = {{Association of Plasma Biomarkers With Longitudinal Atrophy and Microvascular Burden on MRI Across Neurodegenerative and Cerebrovascular Diseases}}, journal = {Neurology}, year = {2025}, doi = {10.1212/wnl.0000000000213438}, pmid = {40063856}, url = {https://doi.org/10.1212/wnl.0000000000213438} } @article{gonzalezortiz2025-40373247, author = {Gonzalez-Ortiz, F. and Kirsebom, B. E. and Yakoub, Y. and Gundersen, J. K. and Pålhaugen, L. and Waterloo, K. and Selnes, P. and Jarholm, J. A. and others}, title = {{Associations Between Changes in Levels of Phosphorylated Tau and Severity of Cognitive Impairment in Early Alzheimer Disease}}, journal = {Neurology}, year = {2025}, doi = {10.1212/wnl.0000000000213676}, pmid = {40373247}, url = {https://doi.org/10.1212/wnl.0000000000213676} } @article{cantoni2025-41359335, author = {Cantoni, V. and Casula, E. P. and Tarantino, B. and Cupidi, C. and Huber, N. and Altomare, D. and Premi, E. and Zummo, E. and others}, title = {{Home-Based Gamma Transcranial Alternating Current Stimulation in Patients With Alzheimer Disease: A Randomized Clinical Trial}}, journal = {JAMA network open}, year = {2025}, doi = {10.1001/jamanetworkopen.2025.46556}, pmid = {41359335}, url = {https://doi.org/10.1001/jamanetworkopen.2025.46556} } @article{frolich2017-29017593, author = {Frölich, L. and Peters, O. and Lewczuk, P. and Gruber, O. and Teipel, S. J. and Gertz, H. J. and Jahn, H. and Jessen, F. and others}, title = {{Incremental value of biomarker combinations to predict progression of mild cognitive impairment to Alzheimer's dementia}}, journal = {Alzheimer's research \& therapy}, year = {2017}, doi = {10.1186/s13195-017-0301-7}, pmid = {29017593}, url = {https://doi.org/10.1186/s13195-017-0301-7} } @article{telser2022-35341762, author = {Telser, Julia and Risch, Lorenz and Saely, Christoph H and Grossmann, Kirsten and Werner, Philipp}, title = {{P-tau217 in Alzheimer's disease}}, journal = {Clinica chimica acta; international journal of clinical chemistry}, year = {2022}, doi = {10.1016/j.cca.2022.03.018}, pmid = {35341762}, url = {https://doi.org/10.1016/j.cca.2022.03.018} } @article{telser2023-37852722, author = {Telser, Julia and Grossmann, Kirsten and Wohlwend, Niklas and Risch, Lorenz and Saely, Christoph H and Werner, Philipp}, title = {{Phosphorylated tau in Alzheimer's disease}}, journal = {Advances in clinical chemistry}, year = {2023}, doi = {10.1016/bs.acc.2023.05.001}, pmid = {37852722}, url = {https://doi.org/10.1016/bs.acc.2023.05.001} } @article{chen2026-41478832, author = {Chen, Xuhui and Jiang, Mingxing and Zhang, Laihong and Zhu, Jiayi and Li, Anqi and He, Zhengbo and Zhou, Xin and Zhu, Yalin and others}, title = {{Association of plasma p-tau and p-tau/Aβ ratio with Alzheimer's pathology}}, journal = {The journal of prevention of Alzheimer's disease}, year = {2026}, doi = {10.1016/j.tjpad.2025.100472}, pmid = {41478832}, url = {https://doi.org/10.1016/j.tjpad.2025.100472} } @article{lorenz2025-41416584, author = {Lorenz, Linda M C and Rohde, Susan K and Luimes, Maruelle C and Rozemuller, Annemieke J M and Bank, Netherlands Brain and Hulsman, Marc and Graat, Marieke J I and van der Hoorn, Myke E and others}, title = {{AD-related plasma biomarkers in centenarians: links to cognition and neuropathology}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2025}, doi = {10.1002/alz.70969}, pmid = {41416584}, url = {https://doi.org/10.1002/alz.70969} } @article{delva2025-40879604, author = {Delva, Aline and Zatti, Cinzia and Pelletier, Amélie and Montplaisir, Jacques and Gagnon, Jean-François and Kollmorgen, Gwendlyn and Kam-Thong, Tony and Kustermann, Thomas and others}, title = {{Plasma Markers of Astrocytic and Axonal Integrity in Idiopathic/Isolated REM Sleep Behavior Disorder (iRBD) as Predictors of Dementia with Lewy Bodies}}, journal = {Movement disorders : official journal of the Movement Disorder Society}, year = {2025}, doi = {10.1002/mds.70016}, pmid = {40879604}, url = {https://doi.org/10.1002/mds.70016} } @article{belder2026-42637536, author = {Belder, Christopher R S and Heslegrave, Amanda J and Swann, Owen and Abel, Emily and Beament, Millie and Nasir, Moneeb and Rice, Helen and Weston, Philip S J and others}, title = {{Presymptomatic plasma biomarkers in autosomal dominant Alzheimer's disease: sequence and timing}}, journal = {Journal of neurology, neurosurgery, and psychiatry}, year = {2026}, doi = {10.1136/jnnp-2026-339037}, pmid = {42637536}, url = {https://doi.org/10.1136/jnnp-2026-339037} } @article{ebenau2022-35110378, author = {Ebenau, Jarith L and Pelkmans, Wiesje and Verberk, Inge M W and Verfaillie, Sander C J and van den Bosch, Karlijn A and van Leeuwenstijn, Mardou and Collij, Lyduine E and Scheltens, Philip and others}, title = {{Association of CSF, Plasma, and Imaging Markers of Neurodegeneration With Clinical Progression in People With Subjective Cognitive Decline}}, journal = {Neurology}, year = {2022}, doi = {10.1212/wnl.0000000000200035}, pmid = {35110378}, url = {https://doi.org/10.1212/wnl.0000000000200035} } @article{burnham2020-32954297, author = {Burnham, Samantha C and Fandos, Noelia and Fowler, Christopher and Pérez-Grijalba, Virginia and Dore, Vincent and Doecke, James D and Shishegar, Rosita and Cox, Timothy and others}, title = {{Longitudinal evaluation of the natural history of amyloid-β in plasma and brain}}, journal = {Brain communications}, year = {2020}, doi = {10.1093/braincomms/fcaa041}, pmid = {32954297}, url = {https://doi.org/10.1093/braincomms/fcaa041} } @article{fischer2023-37752907, author = {Fischer, Barbara and Van Hulle, Carol Ann and Langhough, Rebecca and Norton, Derek and Zuelsdorff, Megan and Gooding, Diane Carol and Wyman, Mary F and Johnson, Adrienne and others}, title = {{Plasma Aβ42/40 and cognitive variability are associated with cognitive function in Black Americans: Findings from the AA-FAIM cohort}}, journal = {Alzheimer's \& dementia (New York, N. Y.)}, year = {2023}, doi = {10.1002/trc2.12414}, pmid = {37752907}, url = {https://doi.org/10.1002/trc2.12414} } @article{hardysosa2022-35360215, author = {Hardy-Sosa, Anette and León-Arcia, Karen and Llibre-Guerra, Jorge J and Berlanga-Acosta, Jorge and Baez, Saiyet de la C and Guillen-Nieto, Gerardo and Valdes-Sosa, Pedro A}, title = {{Diagnostic Accuracy of Blood-Based Biomarker Panels: A Systematic Review}}, journal = {Frontiers in aging neuroscience}, year = {2022}, doi = {10.3389/fnagi.2022.683689}, pmid = {35360215}, url = {https://doi.org/10.3389/fnagi.2022.683689} } @article{zhou2023-37042462, author = {Zhou, Robin Ziyue and Vetrano, Davide Liborio and Grande, Giulia and Duell, Frida and Jönsson, Linus and Laukka, Erika J and Fredolini, Claudia and Winblad, Bengt and others}, title = {{A glycan epitope correlates with tau in serum and predicts progression to Alzheimer's disease in combination with APOE4 allele status}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2023}, doi = {10.1002/alz.13024}, pmid = {37042462}, url = {https://doi.org/10.1002/alz.13024} } @article{monane2023-37550958, author = {Monane, Mark and Johnson, Kim G and Snider, B Joy and Turner, Raymond S and Drake, Jonathan D and Maraganore, Demetrius M and Bicksel, James L and Jacobs, Daniel H and others}, title = {{A blood biomarker test for brain amyloid impacts the clinical evaluation of cognitive impairment}}, journal = {Annals of clinical and translational neurology}, year = {2023}, doi = {10.1002/acn3.51863}, pmid = {37550958}, url = {https://doi.org/10.1002/acn3.51863} } @article{huang2022-bbbbe568, author = {Huang, Li-Kai and Chao, Shu-Ping and Hu, Chaur-Jong and Chien, Li-Nien and Chiou, Hung-Yi and Lo, Yu-Chun and Hsieh, Yi-Chen}, title = {{Plasma Phosphorylated-tau181 Is a Predictor of Post-stroke Cognitive Impairment: A Longitudinal Study}}, journal = {Frontiers in Aging Neuroscience}, year = {2022}, doi = {10.3389/fnagi.2022.889101}, url = {https://doi.org/10.3389/fnagi.2022.889101} } @article{shadyab2026-41805953, author = {Shadyab, A. H. and Zhang, B. and LaCroix, A. Z. and Mielke, M. M. and Resnick, S. M. and Nguyen, S. and Ferrucci, L. and Libermann, T. A. and Ngo, L. and Casanova, R. and others}, title = {{Plasma Phosphorylated Tau 217 and Incident Mild Cognitive Impairment and Dementia in Older Women}}, journal = {JAMA Network Open}, year = {2026}, doi = {10.1001/jamanetworkopen.2026.1295}, pmid = {41805953}, url = {https://doi.org/10.1001/jamanetworkopen.2026.1295} } @article{insel2025-40853684, author = {Insel, P. S. and Mattsson-Carlgren, N. and Langford, O. and Caruso, V. M. and Leuzy, A. and Young, C. B. and Boxer, A. and Aisen, P. S. and Sperling, R. A. and Mormino, E. C. and Donohue, M. C.}, title = {{Concurrent Changes in Plasma Phosphorylated Tau 217, Tau PET, and Cognition in Preclinical Alzheimer Disease}}, journal = {JAMA Neurology}, year = {2025}, doi = {10.1001/jamaneurol.2025.2974}, pmid = {40853684}, url = {https://doi.org/10.1001/jamaneurol.2025.2974} } @article{bornhorst2025-39823562, author = {Bornhorst, J. A. and Lundgreen, C. S. and Weigand, S. D. and Figdore, D. J. and Wiste, H. and Griswold, M. and Vemuri, P. and Graff-Radford, J. and Knopman, D. S. and Cogswell, P. and Jack, C. R. and Petersen, R. C. and others}, title = {{Quantitative Assessment of the Effect of Chronic Kidney Disease on Plasma P-Tau217 Concentrations}}, journal = {Neurology}, year = {2025}, doi = {10.1212/WNL.0000000000210287}, pmid = {39823562}, url = {https://doi.org/10.1212/WNL.0000000000210287} } @article{bridel2019-31206160, author = {Bridel, C. and van Wieringen, W. N. and Zetterberg, H. and Tijms, B. M. and Teunissen, C. E. and {the NFL Group} and Alvarez-Cermeño, J. C. and Andreasson, U. and others}, title = {{Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology: A Systematic Review and Meta-analysis}}, journal = {JAMA neurology}, year = {2019}, doi = {10.1001/jamaneurol.2019.1534}, pmid = {31206160}, url = {https://doi.org/10.1001/jamaneurol.2019.1534} } @article{janelidze2023-36987840, author = {Janelidze, S. and Barthélemy, N. R. and He, Y. and Bateman, R. J. and Hansson, O.}, title = {{Mitigating the Associations of Kidney Dysfunction With Blood Biomarkers of Alzheimer Disease by Using Phosphorylated Tau to Total Tau Ratios}}, journal = {JAMA neurology}, year = {2023}, doi = {10.1001/jamaneurol.2023.0199}, pmid = {36987840}, url = {https://doi.org/10.1001/jamaneurol.2023.0199} } @article{jabbari2020-31860007, author = {Jabbari, E. and Holland, N. and Chelban, V. and Jones, P. S. and Lamb, R. and Rawlinson, C. and Guo, T. and Costantini, A. A. and others}, title = {{Diagnosis Across the Spectrum of Progressive Supranuclear Palsy and Corticobasal Syndrome}}, journal = {JAMA neurology}, year = {2020}, doi = {10.1001/jamaneurol.2019.4347}, pmid = {31860007}, url = {https://doi.org/10.1001/jamaneurol.2019.4347} } @article{ashton2025-39907496, author = {Ashton, N. J. and Keshavan, A. and Brum, W. S. and Andreasson, U. and Arslan, B. and Droescher, M. and Barghorn, S. and Vanbrabant, J. and others}, title = {{The Alzheimer's Association Global Biomarker Standardization Consortium (GBSC) plasma phospho-tau Round Robin study}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2025}, doi = {10.1002/alz.14508}, pmid = {39907496}, url = {https://doi.org/10.1002/alz.14508} } @article{niimi2024-38778353, author = {Niimi, Y. and Janelidze, S. and Sato, K. and Tomita, N. and Tsukamoto, T. and Kato, T. and Yoshiyama, K. and Kowa, H. and others}, title = {{Combining plasma Aβ and p-tau217 improves detection of brain amyloid in non-demented elderly}}, journal = {Alzheimer's research \& therapy}, year = {2024}, doi = {10.1186/s13195-024-01469-w}, pmid = {38778353}, url = {https://doi.org/10.1186/s13195-024-01469-w} } @article{benitez2013-23990795, author = {Benitez, B. A. and Karch, C. M. and Cai, Y. and Jin, S. C. and Cooper, B. and Carrell, D. and Bertelsen, S. and Chibnik, L. and others}, title = {{The PSEN1, p.E318G variant increases the risk of Alzheimer's disease in APOE-ε4 carriers}}, journal = {PLoS genetics}, year = {2013}, doi = {10.1371/journal.pgen.1003685}, pmid = {23990795}, url = {https://doi.org/10.1371/journal.pgen.1003685} } @article{yan2024-38048087, author = {Yan, S. and Jiang, C. and Janzen, A. and Barber, T. R. and Seger, A. and Sommerauer, M. and Davis, J. J. and Marek, K. and others}, title = {{Neuronally Derived Extracellular Vesicle α-Synuclein as a Serum Biomarker for Individuals at Risk of Developing Parkinson Disease}}, journal = {JAMA neurology}, year = {2024}, doi = {10.1001/jamaneurol.2023.4398}, pmid = {38048087}, url = {https://doi.org/10.1001/jamaneurol.2023.4398} } @article{keddie2023-37435933, author = {Keddie, S. and Smyth, D. and Keh, R. Y. S. and Chou, M. K. L. and Grant, D. and Surana, S. and Heslegrave, A. and Zetterberg, H. and others}, title = {{Peripherin is a biomarker of axonal damage in peripheral nervous system disease}}, journal = {Brain : a journal of neurology}, year = {2023}, doi = {10.1093/brain/awad234}, pmid = {37435933}, url = {https://doi.org/10.1093/brain/awad234} } @article{saloner2024-37639492, author = {Saloner, R. and VandeVrede, L. and Asken, B. M. and Paolillo, E. W. and Gontrum, E. Q. and Wolf, A. and Lario-Lago, A. and Milà-Alomà, M. and others}, title = {{Plasma phosphorylated tau-217 exhibits sex-specific prognostication of cognitive decline and brain atrophy in cognitively unimpaired adults}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2024}, doi = {10.1002/alz.13454}, pmid = {37639492}, url = {https://doi.org/10.1002/alz.13454} } @article{khalafi2025-39711334, author = {Khalafi, M. and Dartora, W. J. and McIntire, L. B. J. and Butler, T. A. and Wartchow, K. M. and Hojjati, S. H. and Razlighi, Q. R. and Shirbandi, K. and others}, title = {{Diagnostic accuracy of phosphorylated tau217 in detecting Alzheimer's disease pathology among cognitively impaired and unimpaired: A systematic review and meta-analysis}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2025}, doi = {10.1002/alz.14458}, pmid = {39711334}, url = {https://doi.org/10.1002/alz.14458} } @article{stocker2025-39009700, author = {Stocker, H. and Gentiluomo, M. and Trares, K. and Beyer, L. and Stevenson-Hoare, J. and Rujescu, D. and Holleczek, B. and Beyreuther, K. and others}, title = {{Mitochondrial DNA abundance in blood is associated with Alzheimer's disease- and dementia-risk}}, journal = {Molecular psychiatry}, year = {2025}, doi = {10.1038/s41380-024-02670-x}, pmid = {39009700}, url = {https://doi.org/10.1038/s41380-024-02670-x} } @article{tideman2024-e791e2c1, author = {Tideman, Pontus and Mattsson-Carlgren, Niklas and Schindler, Suzanne E. and Smith, Ruben and Ossenkoppele, Rik and Calling, Susanna and West, Tim and Monane, Mark and Verghese, Philip B. and Braunstein, Joel B. and Blennow, Kaj and Janelidze, Shorena and Stomrud, Erik and Salvadó, Gemma and Hansson, Oskar and Palmqvist, Sebastian}, title = {{Blood Biomarkers to Detect Alzheimer Disease in Primary Care and Secondary Care}}, journal = {JAMA}, year = {2024}, pmid = {39068545} } @article{palmqvist2025-407e7d7f, author = {Palmqvist, Sebastian and Warmenhoven, Noëlle and Anastasi, Federica and Pilotto, Andrea}, title = {{Plasma phospho-tau217 for Alzheimer's disease diagnosis in primary and secondary care using a fully automated platform}}, journal = {Nature Medicine}, year = {2025}, doi = {10.1038/s41591-025-03622-w}, pmid = {40205199}, url = {https://doi.org/10.1038/s41591-025-03622-w} } @article{pan2025-c53cc9a6, author = {Pan, Feng-Feng and Huang, Lin and Wang, Ying and Huang, Qi and Guan, Yi-Hui and Li, Yue-hua and Xie, Fang and Guo, Qi-Hao}, title = {{Plasma P-tau217, GFAP, and NfL as biomarkers for Alzheimer's disease: role in disease stratification, pathological progression, and cognitive decline}}, journal = {Alzheimer's \& Dementia}, year = {2025} } @article{coughlan2026-41697669, author = {Coughlan, Gillian T and Ourry, Valentin and Townsend, Diana and Klinger, Hannah and Brown, Jane A and Cuppels, Madison and Betthauser, Tobey and Langhough, Rebecca and others}, title = {{Sex Differences in P-Tau217, Tau Aggregation, and Cognitive Decline}}, journal = {JAMA neurology}, year = {2026}, doi = {10.1001/jamaneurol.2025.5670}, pmid = {41697669}, url = {https://doi.org/10.1001/jamaneurol.2025.5670} } @article{gasparini2026-41337685, author = {Gasparini, F. and Valletta, M. and Vetrano, D. L. and Beridze, G. and Rizzuto, D. and Calderón-Larrañaga, A. and Fredolini, C. and Dale, M. and Winblad, B. and Fratiglioni, L. and Grande, G.}, title = {{Kidney Function, Alzheimer Disease Blood Biomarkers, and Dementia Risk in Community-Dwelling Older Adults}}, journal = {Neurology}, year = {2026}, doi = {10.1212/WNL.0000000000214446}, pmid = {41337685}, url = {https://doi.org/10.1212/WNL.0000000000214446} } @article{salvado2026-42189519, author = {Salvadó, G. and Horie, K. and Barthélemy, N. R. and Schindler, S. E. and Janelidze, S. and Orduña Dolado, A. and Bali, D. and Perrin, R. J. and Morris, J. C. and Benzinger, T. L. S. and Gordon, B. A. and Stomrud, E. and others}, title = {{Plasma eMTBR-tau243 and \%p-tau217 for Biological Staging of Alzheimer Disease}}, journal = {JAMA Neurology}, year = {2026}, doi = {10.1001/jamaneurol.2026.1405}, pmid = {42189519}, url = {https://doi.org/10.1001/jamaneurol.2026.1405} } @article{sperling2020-32250387, author = {Sperling, R. A. and Donohue, M. C. and Raman, R. and Sun, C. K. and Yaari, R. and Holdridge, K. and Siemers, E. and Johnson, K. A. and others}, title = {{Association of Factors With Elevated Amyloid Burden in Clinically Normal Older Individuals}}, journal = {JAMA neurology}, year = {2020}, doi = {10.1001/jamaneurol.2020.0387}, pmid = {32250387}, url = {https://doi.org/10.1001/jamaneurol.2020.0387} } @article{aschenbrenner2018-30068637, author = {Aschenbrenner, A. J. and Gordon, B. A. and Benzinger, T. L. S. and Morris, J. C. and Hassenstab, J. J.}, title = {{Influence of tau PET, amyloid PET, and hippocampal volume on cognition in Alzheimer disease}}, journal = {Neurology}, year = {2018}, doi = {10.1212/wnl.0000000000006075}, pmid = {30068637}, url = {https://doi.org/10.1212/wnl.0000000000006075} } @article{cicognola2021-33773595, author = {Cicognola, C. and Janelidze, S. and Hertze, J. and Zetterberg, H. and Blennow, K. and Mattsson-Carlgren, N. and Hansson, O.}, title = {{Plasma glial fibrillary acidic protein detects Alzheimer pathology and predicts future conversion to Alzheimer dementia in patients with mild cognitive impairment}}, journal = {Alzheimer's research \& therapy}, year = {2021}, doi = {10.1186/s13195-021-00804-9}, pmid = {33773595}, url = {https://doi.org/10.1186/s13195-021-00804-9} } @article{olsson2019-30508027, author = {Olsson, B. and Portelius, E. and Cullen, N. C. and Å, Sandelius and Zetterberg, H. and Andreasson, U. and Höglund, K. and Irwin, D. J. and others}, title = {{Association of Cerebrospinal Fluid Neurofilament Light Protein Levels With Cognition in Patients With Dementia, Motor Neuron Disease, and Movement Disorders}}, journal = {JAMA neurology}, year = {2019}, doi = {10.1001/jamaneurol.2018.3746}, pmid = {30508027}, url = {https://doi.org/10.1001/jamaneurol.2018.3746} } @article{collij2020-32675080, author = {Collij, L. E. and Heeman, F. and Salvadó, G. and Ingala, S. and Altomare, D. and de Wilde, A. and Konijnenberg, E. and van Buchem, M. and others}, title = {{Multitracer model for staging cortical amyloid deposition using PET imaging}}, journal = {Neurology}, year = {2020}, doi = {10.1212/wnl.0000000000010256}, pmid = {32675080}, url = {https://doi.org/10.1212/wnl.0000000000010256} } @article{therriault2021-33443136, author = {Therriault, J. and Pascoal, T. A. and Benedet, A. L. and Tissot, C. and Savard, M. and Chamoun, M. and Lussier, F. and Kang, M. S. and others}, title = {{Frequency of Biologically Defined Alzheimer Disease in Relation to Age, Sex, APOE ε4, and Cognitive Impairment}}, journal = {Neurology}, year = {2021}, doi = {10.1212/wnl.0000000000011416}, pmid = {33443136}, url = {https://doi.org/10.1212/wnl.0000000000011416} } @article{dittrich2023-37225431, author = {Dittrich, A. and Ashton, N. J. and Zetterberg, H. and Blennow, K. and Zettergren, A. and Simrén, J. and Skillbäck, T. and Shams, S. and others}, title = {{Association of Chronic Kidney Disease With Plasma NfL and Other Biomarkers of Neurodegeneration: The H70 Birth Cohort Study in Gothenburg}}, journal = {Neurology}, year = {2023}, doi = {10.1212/wnl.0000000000207419}, pmid = {37225431}, url = {https://doi.org/10.1212/wnl.0000000000207419} } @article{bolsewig2024-38830138, author = {Bolsewig, K. and van Unnik, A. A. J. M. and Blujdea, E. R. and Gonzalez, M. C. and Ashton, N. J. and Aarsland, D. and Zetterberg, H. and Padovani, A. and others}, title = {{Association of Plasma Amyloid, P-Tau, GFAP, and NfL With CSF, Clinical, and Cognitive Features in Patients With Dementia With Lewy Bodies}}, journal = {Neurology}, year = {2024}, doi = {10.1212/wnl.0000000000209418}, pmid = {38830138}, url = {https://doi.org/10.1212/wnl.0000000000209418} } @article{pichetbinette2025-40388185, author = {Pichet Binette, A. and Smith, R. and Salvadó, G. and Tideman, P. and Glans, I. and van Westen, D. and Groot, C. and Ossenkoppele, R. and others}, title = {{Evaluation of the Revised Criteria for Biological and Clinical Staging of Alzheimer Disease}}, journal = {JAMA neurology}, year = {2025}, doi = {10.1001/jamaneurol.2025.1100}, pmid = {40388185}, url = {https://doi.org/10.1001/jamaneurol.2025.1100} } @article{liu2018-29429971, author = {Liu, E. and Wang, D. and Sperling, R. and Salloway, S. and Fox, N. C. and Blennow, K. and Scheltens, P. and Schmidt, M. E. and others}, title = {{Biomarker pattern of ARIA-E participants in phase 3 randomized clinical trials with bapineuzumab}}, journal = {Neurology}, year = {2018}, doi = {10.1212/wnl.0000000000005060}, pmid = {29429971}, url = {https://doi.org/10.1212/wnl.0000000000005060} } @article{yang2024-38315899, author = {Yang, H. S. and Yau, W. W. and Carlyle, B. C. and Trombetta, B. A. and Zhang, C. and Shirzadi, Z. and Schultz, A. P. and Pruzin, J. J. and others}, title = {{Plasma VEGFA and PGF impact longitudinal tau and cognition in preclinical Alzheimer's disease}}, journal = {Brain : a journal of neurology}, year = {2024}, doi = {10.1093/brain/awae034}, pmid = {38315899}, url = {https://doi.org/10.1093/brain/awae034} } @article{ferreira2025-41364889, author = {Ferreira, Pâmela C.L. and Bellaver, Bruna and Povala, Guilherme and Bauer‐Negrini, Guilherme and Aguzzoli, Cristiano Schaffer and Ferrari‐Souza, João Pedro and Leffa, Douglas Teixeira and Soares, Carolina and others}, title = {{Evaluating Plasma p-tau217 as an Endpoint for Alzheimer Disease Clinical Trials}}, journal = {Neurology}, year = {2025}, doi = {10.1212/wnl.0000000000214441}, pmid = {41364889}, url = {https://doi.org/10.1212/wnl.0000000000214441} } @article{phillips2026-42387213, author = {Phillips, Bridget and Sanford, Jessie and Janve, Vaibhav A and Liu, Menghan and Johnson, Matt and Gong, Katherine and Bergmann, Kristy and Lowery, Joseph and others}, title = {{Blood-based circular RNAs for early diagnosis of Alzheimer's disease}}, journal = {Nature medicine}, year = {2026}, doi = {10.1038/s41591-026-04485-5}, pmid = {42387213}, url = {https://doi.org/10.1038/s41591-026-04485-5} } @article{chen2026-41804834, author = {Chen, Shuai and Hao, Xiaodi and Ma, Kai and Li, Rong and Wen, Changming and Han, Xinsheng and Zheng, Wenquan and Ruan, Shiwang and others}, title = {{Implementing plasma p-tau217 and cognitive testing for Alzheimer's screening in low-education populations in central China}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2026}, doi = {10.1002/alz.71251}, pmid = {41804834}, url = {https://doi.org/10.1002/alz.71251} } @article{krellroesch2023-37529120, author = {Krell-Roesch, Janina and Zaniletti, Isabella and Syrjanen, Jeremy A and Kremers, Walter K and Algeciras-Schimnich, Alicia and Dage, Jeffrey L and van Harten, Argonde C and Fields, Julie A and others}, title = {{Plasma-derived biomarkers of Alzheimer's disease and neuropsychiatric symptoms: A community-based study}}, journal = {Alzheimer's \& dementia (Amsterdam, Netherlands)}, year = {2023}, doi = {10.1002/dad2.12461}, pmid = {37529120}, url = {https://doi.org/10.1002/dad2.12461} } @article{sudre2019-31835286, author = {Sudre, Carole H and Bocchetta, Martina and Heller, Carolin and Convery, Rhian and Neason, Mollie and Moore, Katrina M and Cash, David M and Thomas, David L and others}, title = {{White matter hyperintensities in progranulin-associated frontotemporal dementia: A longitudinal GENFI study}}, journal = {NeuroImage. Clinical}, year = {2019}, doi = {10.1016/j.nicl.2019.102077}, pmid = {31835286}, url = {https://doi.org/10.1016/j.nicl.2019.102077} } @article{dark2024-38689358, author = {Dark, Heather E and An, Yang and Duggan, Michael R and Joynes, Cassandra and Davatzikos, Christos and Erus, Guray and Lewis, Alexandria and Moghekar, Abhay R and others}, title = {{Alzheimer's and neurodegenerative disease biomarkers in blood predict brain atrophy and cognitive decline}}, journal = {Alzheimer's research \& therapy}, year = {2024}, doi = {10.1186/s13195-024-01459-y}, pmid = {38689358}, url = {https://doi.org/10.1186/s13195-024-01459-y} } @article{kapoor2023-37156179, author = {Kapoor, Arunima and Gaubert, Aimée and Yew, Belinda and Jang, Jung Yun and Dutt, Shubir and Li, Yanrong and Alitin, John Paul M and Nguyen, Amy and others}, title = {{Enlarged perivascular spaces and plasma Aβ42/Aβ40 ratio in older adults without dementia}}, journal = {Neurobiology of aging}, year = {2023}, doi = {10.1016/j.neurobiolaging.2023.04.004}, pmid = {37156179}, url = {https://doi.org/10.1016/j.neurobiolaging.2023.04.004} } @article{verde2022-36108600, author = {Verde, Federico and Aiello, Edoardo Nicolò and Grigoli, Eleonora Giacopuzzi and Milone, Ilaria and Dubini, Antonella and Ratti, Antonia and Poletti, Barbara and Ticozzi, Nicola and others}, title = {{CSF Aβ40 and P-Tau181 Might Differentiate Atypical from Typical AD Phenotypes: Preliminary Evidence}}, journal = {Neuro-degenerative diseases}, year = {2022}, doi = {10.1159/000526888}, pmid = {36108600}, url = {https://doi.org/10.1159/000526888} } @article{gonzalezescalante2025-40414160, author = {González-Escalante, Armand and Milà-Alomà, Marta and Brum, Wagner S and Ashton, Nicholas J and Ortiz-Romero, Paula and Shekari, Mahnaz and Del Campo, Marta and Anastasi, Federica and others}, title = {{A plasma biomarker panel for detecting early amyloid-β accumulation and its changes in middle-aged cognitively unimpaired individuals at risk for Alzheimer's disease}}, journal = {EBioMedicine}, year = {2025}, doi = {10.1016/j.ebiom.2025.105741}, pmid = {40414160}, url = {https://doi.org/10.1016/j.ebiom.2025.105741} } @article{xie2026-42021299, author = {Xie, Siqi and Liang, Yumei and Pang, Yana and Li, Ying and Cao, Shuman and Li, Yan and Wang, Qi and Moghekar, Abhay and others}, title = {{Plasma biomarker trajectories across Alzheimer's clinical onset: a 17-year prospective study}}, journal = {Alzheimer's research \& therapy}, year = {2026}, doi = {10.1186/s13195-026-02045-0}, pmid = {42021299}, url = {https://doi.org/10.1186/s13195-026-02045-0} } @article{buckley2026-42449500, author = {Buckley, Rachel F and Townsend, Diana L and Birkenbihl, Colin J and Cuppels, Madison and Coughlan, Gillian T and Seto, Mabel T and Brown, Jane A and Properzi, Michael J and others}, title = {{Prognostic Value of Blood-Based P-Tau217 Levels for Progression to Cognitive Impairment}}, journal = {JAMA}, year = {2026}, doi = {10.1001/jama.2026.12556}, pmid = {42449500}, url = {https://doi.org/10.1001/jama.2026.12556} } @article{zetterberg2016-26524180, author = {Zetterberg, H. and Skillbäck, T. and Mattsson, N. and Trojanowski, J. Q. and Portelius, E. and Shaw, L. M. and Weiner, M. W. and Blennow, K. and others}, title = {{Association of Cerebrospinal Fluid Neurofilament Light Concentration With Alzheimer Disease Progression}}, journal = {JAMA neurology}, year = {2016}, doi = {10.1001/jamaneurol.2015.3037}, pmid = {26524180}, url = {https://doi.org/10.1001/jamaneurol.2015.3037} } @article{khalil2024-38609644, author = {Khalil, M. and Teunissen, C. E. and Lehmann, S. and Otto, M. and Piehl, F. and Ziemssen, T. and Bittner, S. and Sormani, M. P. and others}, title = {{Neurofilaments as biomarkers in neurological disorders - towards clinical application}}, journal = {Nature reviews. Neurology}, year = {2024}, doi = {10.1038/s41582-024-00955-x}, pmid = {38609644}, url = {https://doi.org/10.1038/s41582-024-00955-x} } @article{horie2023-37443334, author = {Horie, K. and Salvadó, G. and Barthélemy, N. R. and Janelidze, S. and Li, Y. and He, Y. and Saef, B. and Chen, C. D. and others}, title = {{CSF MTBR-tau243 is a specific biomarker of tau tangle pathology in Alzheimer's disease}}, journal = {Nature medicine}, year = {2023}, doi = {10.1038/s41591-023-02443-z}, pmid = {37443334}, url = {https://doi.org/10.1038/s41591-023-02443-z} } @article{mattsson2019-31314895, author = {Mattsson, N. and Palmqvist, S. and Stomrud, E. and Vogel, J. and Hansson, O.}, title = {{Staging β-Amyloid Pathology With Amyloid Positron Emission Tomography}}, journal = {JAMA neurology}, year = {2019}, doi = {10.1001/jamaneurol.2019.2214}, pmid = {31314895}, url = {https://doi.org/10.1001/jamaneurol.2019.2214} } @article{li2022-34906975, author = {Li, Y. and Schindler, S. E. and Bollinger, J. G. and Ovod, V. and Mawuenyega, K. G. and Weiner, M. W. and Shaw, L. M. and Masters, C. L. and others}, title = {{Validation of Plasma Amyloid-β 42/40 for Detecting Alzheimer Disease Amyloid Plaques}}, journal = {Neurology}, year = {2022}, doi = {10.1212/wnl.0000000000013211}, pmid = {34906975}, url = {https://doi.org/10.1212/wnl.0000000000013211} } @article{verberk2021-36098162, author = {Verberk, I. M. W. and Laarhuis, M. B. and van den Bosch, K. A. and Ebenau, J. L. and van Leeuwenstijn, M. and Prins, N. D. and Scheltens, P. and Teunissen, C. E. and others}, title = {{Serum markers glial fibrillary acidic protein and neurofilament light for prognosis and monitoring in cognitively normal older people: a prospective memory clinic-based cohort study}}, journal = {The lancet. Healthy longevity}, year = {2021}, doi = {10.1016/s2666-7568(20)30061-1}, pmid = {36098162}, url = {https://doi.org/10.1016/s2666-7568(20)30061-1} } @article{mattssoncarlgren2020-32398359, author = {Mattsson-Carlgren, N. and Leuzy, A. and Janelidze, S. and Palmqvist, S. and Stomrud, E. and Strandberg, O. and Smith, R. and Hansson, O.}, title = {{The implications of different approaches to define AT(N) in Alzheimer disease}}, journal = {Neurology}, year = {2020}, doi = {10.1212/wnl.0000000000009485}, pmid = {32398359}, url = {https://doi.org/10.1212/wnl.0000000000009485} } @article{gertje2023-36882326, author = {Gertje, E. C. and Janelidze, S. and van Westen, D. and Cullen, N. and Stomrud, E. and Palmqvist, S. and Hansson, O. and Mattsson-Carlgren, N.}, title = {{Associations Between CSF Markers of Inflammation, White Matter Lesions, and Cognitive Decline in Individuals Without Dementia}}, journal = {Neurology}, year = {2023}, doi = {10.1212/wnl.0000000000207113}, pmid = {36882326}, url = {https://doi.org/10.1212/wnl.0000000000207113} } @article{nguyenho2024-38913396, author = {Nguyen Ho, P. T. and Hoepel, S. J. W. and Rodriguez-Ayllon, M. and Luik, A. I. and Vernooij, M. W. and Neitzel, J.}, title = {{Sleep, 24-Hour Activity Rhythms, and Subsequent Amyloid-β Pathology}}, journal = {JAMA neurology}, year = {2024}, doi = {10.1001/jamaneurol.2024.1755}, pmid = {38913396}, url = {https://doi.org/10.1001/jamaneurol.2024.1755} } @article{wisch2024-38631766, author = {Wisch, J. K. and McKay, N. S. and Boerwinkle, A. H. and Kennedy, J. and Flores, S. and Handen, B. L. and Christian, B. T. and Head, E. and others}, title = {{Comparison of tau spread in people with Down syndrome versus autosomal-dominant Alzheimer's disease: a cross-sectional study}}, journal = {The Lancet. Neurology}, year = {2024}, doi = {10.1016/s1474-4422(24)00084-x}, pmid = {38631766}, url = {https://doi.org/10.1016/s1474-4422(24)00084-x} } @article{shaw2009-19296504, author = {Shaw, Leslie M. and Vanderstichele, Hugo and Knapik-Czajka, Malgorzata Elzbieta and Clark, Christopher M. and Aisen, Paul S. S. and Petersen, Ronald Carl and Blennow, Kaj and Soares, Holly D and others}, title = {{Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects}}, journal = {Annals of Neurology}, year = {2009}, doi = {10.1002/ana.21610}, pmid = {19296504}, url = {https://doi.org/10.1002/ana.21610} } @article{salvado2023-36912178, author = {Salvadó, G. and Ossenkoppele, R. and Ashton, N. J. and Beach, T. G. and Serrano, G. E. and Reiman, E. M. and Zetterberg, H. and Mattsson-Carlgren, N. and others}, title = {{Specific associations between plasma biomarkers and postmortem amyloid plaque and tau tangle loads}}, journal = {EMBO molecular medicine}, year = {2023}, doi = {10.15252/emmm.202217123}, pmid = {36912178}, url = {https://doi.org/10.15252/emmm.202217123} } @article{chouliaras2022-35078917, author = {Chouliaras, L. and Thomas, A. and Malpetti, M. and Donaghy, P. and Kane, J. and Mak, E. and Savulich, G. and Prats-Sedano, M. A. and others}, title = {{Differential levels of plasma biomarkers of neurodegeneration in Lewy body dementia, Alzheimer's disease, frontotemporal dementia and progressive supranuclear palsy}}, journal = {Journal of neurology, neurosurgery, and psychiatry}, year = {2022}, doi = {10.1136/jnnp-2021-327788}, pmid = {35078917}, url = {https://doi.org/10.1136/jnnp-2021-327788} } @article{garrett2019-31834392, author = {Garrett, S. L. and McDaniel, D. and Obideen, M. and Trammell, A. R. and Shaw, L. M. and Goldstein, F. C. and Hajjar, I.}, title = {{Racial Disparity in Cerebrospinal Fluid Amyloid and Tau Biomarkers and Associated Cutoffs for Mild Cognitive Impairment}}, journal = {JAMA network open}, year = {2019}, doi = {10.1001/jamanetworkopen.2019.17363}, pmid = {31834392}, url = {https://doi.org/10.1001/jamanetworkopen.2019.17363} } @article{zeng2024-39385222, author = {Zeng, X. and Lafferty, T. K. and Sehrawat, A. and Chen, Y. and Ferreira, P. C. L. and Bellaver, B. and Povala, G. and Kamboh, M. I. and others}, title = {{Multi-analyte proteomic analysis identifies blood-based neuroinflammation, cerebrovascular and synaptic biomarkers in preclinical Alzheimer's disease}}, journal = {Molecular neurodegeneration}, year = {2024}, doi = {10.1186/s13024-024-00753-5}, pmid = {39385222}, url = {https://doi.org/10.1186/s13024-024-00753-5} } @article{bilgel2023-37216632, author = {Bilgel, M. and An, Y. and Walker, K. A. and Moghekar, A. R. and Ashton, N. J. and Kac, P. R. and Karikari, T. K. and Blennow, K. and others}, title = {{Longitudinal changes in Alzheimer's-related plasma biomarkers and brain amyloid}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2023}, doi = {10.1002/alz.13157}, pmid = {37216632}, url = {https://doi.org/10.1002/alz.13157} } @article{mattsson2016-27534871, author = {Mattsson, N. and Insel, P. S. and Palmqvist, S. and Portelius, E. and Zetterberg, H. and Weiner, M. and Blennow, K. and Hansson, O. and others}, title = {{Cerebrospinal fluid tau, neurogranin, and neurofilament light in Alzheimer's disease}}, journal = {EMBO molecular medicine}, year = {2016}, doi = {10.15252/emmm.201606540}, pmid = {27534871}, url = {https://doi.org/10.15252/emmm.201606540} } @article{gaiani2017-28264096, author = {Gaiani, A. and Martinelli, I. and Bello, L. and Querin, G. and Puthenparampil, M. and Ruggero, S. and Toffanin, E. and Cagnin, A. and others}, title = {{Diagnostic and Prognostic Biomarkers in Amyotrophic Lateral Sclerosis: Neurofilament Light Chain Levels in Definite Subtypes of Disease}}, journal = {JAMA neurology}, year = {2017}, doi = {10.1001/jamaneurol.2016.5398}, pmid = {28264096}, url = {https://doi.org/10.1001/jamaneurol.2016.5398} } @article{qu2021-34245759, author = {Qu, Y. and Ma, Y. H. and Huang, Y. Y. and Ou, Y. N. and Shen, X. N. and Chen, S. D. and Dong, Q. and Tan, L. and others}, title = {{Blood biomarkers for the diagnosis of amnestic mild cognitive impairment and Alzheimer's disease: A systematic review and meta-analysis}}, journal = {Neuroscience and biobehavioral reviews}, year = {2021}, doi = {10.1016/j.neubiorev.2021.07.007}, pmid = {34245759}, url = {https://doi.org/10.1016/j.neubiorev.2021.07.007} } @article{casanova2016-26806385, author = {Casanova, R. and Varma, S. and Simpson, B. and Kim, M. and An, Y. and Saldana, S. and Riveros, C. and Moscato, P. and others}, title = {{Blood metabolite markers of preclinical Alzheimer's disease in two longitudinally followed cohorts of older individuals}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2016}, doi = {10.1016/j.jalz.2015.12.008}, pmid = {26806385}, url = {https://doi.org/10.1016/j.jalz.2015.12.008} } @article{heimfarth2022-35255304, author = {Heimfarth, L. and Passos, F. R. S. and Monteiro, B. S. and Araújo, A. A. S. and Quintans Júnior, L. J. and Quintans, J. S. S.}, title = {{Serum glial fibrillary acidic protein is a body fluid biomarker: A valuable prognostic for neurological disease - A systematic review}}, journal = {International immunopharmacology}, year = {2022}, doi = {10.1016/j.intimp.2022.108624}, pmid = {35255304}, url = {https://doi.org/10.1016/j.intimp.2022.108624} } @article{yakoub2023-37294682, author = {Yakoub, Y. and Ashton, N. J. and Strikwerda-Brown, C. and Montoliu-Gaya, L. and Karikari, T. K. and Kac, P. R. and Gonzalez-Ortiz, F. and Gallego-Rudolf, J. and others}, title = {{Longitudinal blood biomarker trajectories in preclinical Alzheimer's disease}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2023}, doi = {10.1002/alz.13318}, pmid = {37294682}, url = {https://doi.org/10.1002/alz.13318} } @article{stocker2023-37516890, author = {Stocker, H. and Trares, K. and Beyer, L. and Perna, L. and Rujescu, D. and Holleczek, B. and Beyreuther, K. and Gerwert, K. and others}, title = {{Alzheimer's polygenic risk scores, APOE, Alzheimer's disease risk, and dementia-related blood biomarker levels in a population-based cohort study followed over 17 years}}, journal = {Alzheimer's research \& therapy}, year = {2023}, doi = {10.1186/s13195-023-01277-8}, pmid = {37516890}, url = {https://doi.org/10.1186/s13195-023-01277-8} } @article{martinoadami2022-35088840, author = {Martino Adami, P. V. and Orellana, A. and García, P. and Kleineidam, L. and Alarcón-Martín, E. and Montrreal, L. and Aguilera, N. and Espinosa, A. and others}, title = {{Matrix metalloproteinase 10 is linked to the risk of progression to dementia of the Alzheimer's type}}, journal = {Brain : a journal of neurology}, year = {2022}, doi = {10.1093/brain/awac024}, pmid = {35088840}, url = {https://doi.org/10.1093/brain/awac024} } @article{vacchiano2023-37012065, author = {Vacchiano, V. and Mastrangelo, A. and Zenesini, C. and Baiardi, S. and Avoni, P. and Polischi, B. and Capellari, S. and Salvi, F. and others}, title = {{Elevated plasma p-tau181 levels unrelated to Alzheimer's disease pathology in amyotrophic lateral sclerosis}}, journal = {Journal of neurology, neurosurgery, and psychiatry}, year = {2023}, doi = {10.1136/jnnp-2022-330709}, pmid = {37012065}, url = {https://doi.org/10.1136/jnnp-2022-330709} } @article{koychev2021-33252080, author = {Koychev, I. and Jansen, K. and Dette, A. and Shi, L. and Holling, H.}, title = {{Blood-Based ATN Biomarkers of Alzheimer's Disease: A Meta-Analysis}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2021}, doi = {10.3233/jad-200900}, pmid = {33252080}, url = {https://doi.org/10.3233/jad-200900} } @article{du2024-38970274, author = {Du, L. and Langhough, R. E. and Wilson, R. E. and Reyes, R. E. R. and Hermann, B. P. and Jonaitis, E. M. and Betthauser, T. J. and Chin, N. A. and others}, title = {{Longitudinal plasma phosphorylated-tau217 and other related biomarkers in a non-demented Alzheimer's risk-enhanced sample}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2024}, doi = {10.1002/alz.14100}, pmid = {38970274}, url = {https://doi.org/10.1002/alz.14100} } @article{chen2022-35847667, author = {Chen, Y. H. and Lin, R. R. and Huang, H. F. and Xue, Y. Y. and Tao, Q. Q.}, title = {{Microglial Activation, Tau Pathology, and Neurodegeneration Biomarkers Predict Longitudinal Cognitive Decline in Alzheimer's Disease Continuum}}, journal = {Frontiers in aging neuroscience}, year = {2022}, doi = {10.3389/fnagi.2022.848180}, pmid = {35847667}, url = {https://doi.org/10.3389/fnagi.2022.848180} } @article{alty2022-35850660, author = {Alty, J. and Bai, Q. and Li, R. and Lawler, K. and St George, R. J. and Hill, E. and Bindoff, A. and Garg, S. and others}, title = {{The TAS Test project: a prospective longitudinal validation of new online motor-cognitive tests to detect preclinical Alzheimer's disease and estimate 5-year risks of cognitive decline and dementia}}, journal = {BMC neurology}, year = {2022}, doi = {10.1186/s12883-022-02772-5}, pmid = {35850660}, url = {https://doi.org/10.1186/s12883-022-02772-5} } @article{nordengen2023-38093257, author = {Nordengen, K. and Kirsebom, B. E. and Richter, G. and Pålhaugen, L. and Gísladóttir, B. and Siafarikas, N. and Nakling, A. and Rongve, A. and others}, title = {{Longitudinal cerebrospinal fluid measurements show glial hypo- and hyperactivation in predementia Alzheimer's disease}}, journal = {Journal of neuroinflammation}, year = {2023}, doi = {10.1186/s12974-023-02973-w}, pmid = {38093257}, url = {https://doi.org/10.1186/s12974-023-02973-w} } @article{capuano2025-41151002, author = {Capuano, A. W. and Bennett, D. A. and Dage, J. L. and Russ, K. A. and Arfanakis, K. and Lamar, M. and Barnes, L. L. and Schneider, J. A.}, title = {{Assessing Cognitive Decline and Dementia Risk in Black and White Older Adults With Blood Biomarkers pTau217, GFAP, NfL, and Aβ Ratio}}, journal = {Neurology}, year = {2025}, doi = {10.1212/WNL.0000000000214317}, pmid = {41151002}, url = {https://doi.org/10.1212/WNL.0000000000214317} } @article{rajan2020-32799383, author = {Rajan, K. B. and Aggarwal, N. T. and McAninch, E. A. and Weuve, J. and Barnes, L. L. and Wilson, R. S. and DeCarli, C. and others}, title = {{Remote Blood Biomarkers of Longitudinal Cognitive Outcomes in a Population Study}}, journal = {Annals of neurology}, year = {2020}, doi = {10.1002/ana.25874}, pmid = {32799383}, url = {https://doi.org/10.1002/ana.25874} } @article{vandevrede2023-37010841, author = {VandeVrede, L. and La Joie, R. and Thijssen, E. H. and Asken, B. M. and Vento, S. A. and Tsuei, T. and Baker, S. L. and Cobigo, Y. and others}, title = {{Evaluation of Plasma Phosphorylated Tau217 for Differentiation Between Alzheimer Disease and Frontotemporal Lobar Degeneration Subtypes Among Patients With Corticobasal Syndrome}}, journal = {JAMA neurology}, year = {2023}, doi = {10.1001/jamaneurol.2023.0488}, pmid = {37010841}, url = {https://doi.org/10.1001/jamaneurol.2023.0488} } @article{rajan2023-36446595, author = {Rajan, K. B. and McAninch, E. A. and Aggarwal, N. T. and Barnes, L. L. and Wilson, R. S. and Weuve, J. and DeCarli, C. S. and Evans, D. A.}, title = {{Longitudinal Changes in Blood Biomarkers of Clinical Alzheimer Disease in a Biracial Population Sample}}, journal = {Neurology}, year = {2023}, doi = {10.1212/wnl.0000000000201289}, pmid = {36446595}, url = {https://doi.org/10.1212/wnl.0000000000201289} } @article{kivisakk2026-41610380, author = {Kivisäkk, Pia and Fatima, Hadia A. and Wu, Chao‐Yi and Padmanabhan, Nikhil and Romero, Daniel and Gorham, Taron and Weik, Molly and Dodge, Hiroko H. and others}, title = {{Postmortem Associations Between Alzheimer Disease Pathology and Plasma pTau217, GFAP, and NfL in AD and AD-Related Dementias}}, journal = {Neurology}, year = {2026}, doi = {10.1212/wnl.0000000000214351}, pmid = {41610380}, url = {https://doi.org/10.1212/wnl.0000000000214351} } @article{shen2021-34775468, author = {Shen, X. N. and Huang, Y. Y. and Chen, S. D. and Guo, Y. and Tan, L. and Dong, Q. and Yu, J. T. and {Alzheimer’s Disease Neuroimaging Initiative}}, title = {{Plasma phosphorylated-tau181 as a predictive biomarker for Alzheimer's amyloid, tau and FDG PET status}}, journal = {Translational psychiatry}, year = {2021}, doi = {10.1038/s41398-021-01709-9}, pmid = {34775468}, url = {https://doi.org/10.1038/s41398-021-01709-9} } @article{gaiottino2013-24073237, author = {Gaiottino, J. and Norgren, N. and Dobson, R. and Topping, J. and Nissim, A. and Malaspina, A. and Bestwick, J. P. and Monsch, A. U. and others}, title = {{Increased neurofilament light chain blood levels in neurodegenerative neurological diseases}}, journal = {PloS one}, year = {2013}, doi = {10.1371/journal.pone.0075091}, pmid = {24073237}, url = {https://doi.org/10.1371/journal.pone.0075091} } @article{verde2019-30309882, author = {Verde, F. and Steinacker, P. and Weishaupt, J. H. and Kassubek, J. and Oeckl, P. and Halbgebauer, S. and Tumani, H. and von Arnim, C. A. F. and others}, title = {{Neurofilament light chain in serum for the diagnosis of amyotrophic lateral sclerosis}}, journal = {Journal of neurology, neurosurgery, and psychiatry}, year = {2019}, doi = {10.1136/jnnp-2018-318704}, pmid = {30309882}, url = {https://doi.org/10.1136/jnnp-2018-318704} } @article{carlyle2022-35734478, author = {Carlyle, B. C. and Kitchen, R. R. and Mattingly, Z. and Celia, A. M. and Trombetta, B. A. and Das, S. and Hyman, B. T. and Kivisäkk, P. and others}, title = {{Technical Performance Evaluation of Olink Proximity Extension Assay for Blood-Based Biomarker Discovery in Longitudinal Studies of Alzheimer's Disease}}, journal = {Frontiers in neurology}, year = {2022}, doi = {10.3389/fneur.2022.889647}, pmid = {35734478}, url = {https://doi.org/10.3389/fneur.2022.889647} } @article{mengel2020-32192521, author = {Mengel, D. and Liu, W. and Glynn, R. J. and Selkoe, D. J. and Strydom, A. and Lai, F. and Rosas, H. D. and Torres, A. and others}, title = {{Dynamics of plasma biomarkers in Down syndrome: the relative levels of Aβ42 decrease with age, whereas NT1 tau and NfL increase}}, journal = {Alzheimer's research \& therapy}, year = {2020}, doi = {10.1186/s13195-020-00593-7}, pmid = {32192521}, url = {https://doi.org/10.1186/s13195-020-00593-7} } @article{anastasi2025-39998475, author = {Anastasi, Federica and Fernández-Lebrero, Aida and Ashton, Nicholas J and Ortiz-Romero, Paula and Torres-Torronteras, Javier and González-Escalante, Armand and Milà-Alomà, Marta and Contador, José and others}, title = {{A head-to-head comparison of plasma biomarkers to detect Alzheimer's disease in a memory clinic}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2025}, doi = {10.1002/alz.14609}, pmid = {39998475}, url = {https://doi.org/10.1002/alz.14609} } @article{arranz2026-42435584, author = {Arranz, Javier and Lantero-Rodríguez, Juan and Braun-Wohlfahrt, Luisa Sophie and Vaqué-Alcázar, Lídia and Rodríguez-Baz, Íñigo and Kac, Przemysław R and Arslan, Burak and Maure-Blesa, Lucía and others}, title = {{CSF and plasma tau biomarkers in the Down syndrome-Alzheimer's disease continuum}}, journal = {EBioMedicine}, year = {2026}, doi = {10.1016/j.ebiom.2026.106370}, pmid = {42435584}, url = {https://doi.org/10.1016/j.ebiom.2026.106370} } @article{arias2025-39879633, author = {Arias, Jaime Fernández and Brum, Wagner S and Salvadó, Gemma and Therriault, Joseph and Servaes, Stijn and Wang, Yi-Ting and Aumont, Etienne and Rahmouni, Nesrine and others}, title = {{Plasma phosphorylated tau217 strongly associates with memory deficits in the Alzheimer's disease spectrum}}, journal = {Brain : a journal of neurology}, year = {2025}, doi = {10.1093/brain/awaf033}, pmid = {39879633}, url = {https://doi.org/10.1093/brain/awaf033} } @article{terracciano2023-37210782, author = {Terracciano, Antonio and Walker, Keenan and An, Yang and Luchetti, Martina and Stephan, Yannick and Moghekar, Abhay R and Sutin, Angelina R and Ferrucci, Luigi and others}, title = {{The association between personality and plasma biomarkers of astrogliosis and neuronal injury}}, journal = {Neurobiology of aging}, year = {2023}, doi = {10.1016/j.neurobiolaging.2023.04.011}, pmid = {37210782}, url = {https://doi.org/10.1016/j.neurobiolaging.2023.04.011} } @article{gotze2023-36462720, author = {Götze, Karl and Vrillon, Agathe and Bouaziz-Amar, Elodie and Mouton-Liger, François and Hugon, Jacques and Martinet, Matthieu and Dumurgier, Julien and Cognat, Emmanuel and others}, title = {{Plasma neurofilament light chain in memory clinic practice: Evidence from a real-life study}}, journal = {Neurobiology of disease}, year = {2023}, doi = {10.1016/j.nbd.2022.105937}, pmid = {36462720}, url = {https://doi.org/10.1016/j.nbd.2022.105937} } @article{saji2022-35180112, author = {Saji, Naoki and Murotani, Kenta and Sato, Naoyuki and Tsuduki, Tsuyoshi and Hisada, Takayoshi and Shinohara, Mitsuru and Sugimoto, Taiki and Niida, Shumpei and others}, title = {{Relationship Between Plasma Neurofilament Light Chain, Gut Microbiota, and Dementia: A Cross-Sectional Study}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2022}, doi = {10.3233/jad-215141}, pmid = {35180112}, url = {https://doi.org/10.3233/jad-215141} } @article{kamps2025-40481074, author = {Kamps, Suzie and van Amerongen, Suzan and Blujdea, Elena R and Hoppen, Marloes I and Bongers, Bram and Schelvis, Kasper H and Caton, Dewi K and Königs, Marsh and others}, title = {{Plasma and MRI biomarkers capture neuronal damage in former professional boxers}}, journal = {Scientific reports}, year = {2025}, doi = {10.1038/s41598-025-93066-6}, pmid = {40481074}, url = {https://doi.org/10.1038/s41598-025-93066-6} } @article{wang2022-36575499, author = {Wang, Jijing and Zhang, Ya-Ru and Shen, Xue-Ning and Han, Jinming and Cui, Mei and Tan, Lan and Dong, Qiang and Zubarev, Roman A and others}, title = {{Deamidation-related blood biomarkers show promise for early diagnostics of neurodegeneration}}, journal = {Biomarker research}, year = {2022}, doi = {10.1186/s40364-022-00435-8}, pmid = {36575499}, url = {https://doi.org/10.1186/s40364-022-00435-8} } @article{agosta2026-41857623, author = {Agosta, Federica and Cecchetti, Giordano and Spinelli, Edoardo G and Ghirelli, Alma and Rugarli, Giulia and Pisano, Stefano and Coraglia, Federico and Canu, Elisa and others}, title = {{Real-world implementation of lecanemab and donanemab in an Italian memory center: a 1-year experience}}, journal = {Alzheimer's research \& therapy}, year = {2026}, doi = {10.1186/s13195-026-02015-6}, pmid = {41857623}, url = {https://doi.org/10.1186/s13195-026-02015-6} } @article{wang2025-40520530, author = {Wang, Xin and Bakulski, Kelly M and Karvonen-Gutierrez, Carrie A and Park, Sung Kyun and Morgan, David and Jackson, Brian P and Albin, Roger L and Paulson, Henry L}, title = {{Blood essential trace elements and Alzheimer's disease biomarkers in midlife}}, journal = {Frontiers in aging neuroscience}, year = {2025}, doi = {10.3389/fnagi.2025.1539749}, pmid = {40520530}, url = {https://doi.org/10.3389/fnagi.2025.1539749} } @article{feizpour2026-41478830, author = {Feizpour, Azadeh and Doré, Vincent and Bourgeat, Pierrick and Doecke, James D and Canovas, Rodrigo and Laws, Simon M and Porter, Tenielle and Huang, Kun and others}, title = {{Plasma Aβ42/40 predicts progression from Aβ-amyloid negative to positive PET scans}}, journal = {The journal of prevention of Alzheimer's disease}, year = {2026}, doi = {10.1016/j.tjpad.2025.100455}, pmid = {41478830}, url = {https://doi.org/10.1016/j.tjpad.2025.100455} } @article{kasuga2026-41653881, author = {Kasuga, Kensaku and Kikuchi, Masataka and Kikkawa-Saito, Emiko and Tsukie, Tamao and Ishiguro, Takanobu and Miyashita, Akinori and Iwatsubo, Takeshi and {Japanese Alzheimer’s Disease Neuroimaging Initiative} and others}, title = {{Evaluation of plasma p-tau217 biomarkers in detecting amyloid pathology and predicting cognitive outcomes: Observations from Japanese Alzheimer's disease neuroimaging initiative cohort}}, journal = {The journal of prevention of Alzheimer's disease}, year = {2026}, doi = {10.1016/j.tjpad.2026.100502}, pmid = {41653881}, url = {https://doi.org/10.1016/j.tjpad.2026.100502} } @article{mundada2023-37740209, author = {Mundada, N. S. and Rojas, J. C. and Vandevrede, L. and Thijssen, E. H. and Iaccarino, L. and Okoye, O. C. and Shankar, R. and Soleimani-Meigooni, D. N. and others}, title = {{Head-to-head comparison between plasma p-tau217 and flortaucipir-PET in amyloid-positive patients with cognitive impairment}}, journal = {Alzheimer's research \& therapy}, year = {2023}, doi = {10.1186/s13195-023-01302-w}, pmid = {37740209}, url = {https://doi.org/10.1186/s13195-023-01302-w} } @article{ferrarisouza2023-37749258, author = {Ferrari-Souza, J. P. and Bellaver, B. and Ferreira, P. C. L. and Benedet, A. L. and Povala, G. and Lussier, F. Z. and Leffa, D. T. and Therriault, J. and others}, title = {{APOEε4 potentiates amyloid β effects on longitudinal tau pathology}}, journal = {Nature aging}, year = {2023}, doi = {10.1038/s43587-023-00490-2}, pmid = {37749258}, url = {https://doi.org/10.1038/s43587-023-00490-2} } @article{chong2025-39807654, author = {Chong, JR. and Hilal, S. and Tan, B. Y. and Venketasubramanian, N. and Schöll, M. and Zetterberg, H. and Blennow, K. and Ashton, N. J. and others}, title = {{Clinical utility of plasma p-tau217 in identifying abnormal brain amyloid burden in an Asian cohort with high prevalence of concomitant cerebrovascular disease}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2025}, doi = {10.1002/alz.14502}, pmid = {39807654}, url = {https://doi.org/10.1002/alz.14502} } @article{lussier2021-33959711, author = {Lussier, F. Z. and Benedet, A. L. and Therriault, J. and Pascoal, T. A. and Tissot, C. and Chamoun, M. and Mathotaarachchi, S. and Savard, M. and others}, title = {{Plasma levels of phosphorylated tau 181 are associated with cerebral metabolic dysfunction in cognitively impaired and amyloid-positive individuals}}, journal = {Brain communications}, year = {2021}, doi = {10.1093/braincomms/fcab073}, pmid = {33959711}, url = {https://doi.org/10.1093/braincomms/fcab073} } @article{shi2020-31336382, author = {Shi, Y. and Gu, L. and Wang, Q. and Gao, L. and Zhu, J. and Lu, X. and Zhou, F. and Zhu, D. and others}, title = {{Platelet Amyloid-β Protein Precursor (AβPP) Ratio and Phosphorylated Tau as Promising Indicators for Early Alzheimer's Disease}}, journal = {The journals of gerontology. Series A, Biological sciences and medical sciences}, year = {2020}, doi = {10.1093/gerona/glz005}, pmid = {31336382}, url = {https://doi.org/10.1093/gerona/glz005} } @article{gonzalezortiz2024-39502943, author = {Gonzalez-Ortiz, F. and Karikari, T. K. and Taylor-Te Vruchte, D. and Shepherd, D. and Kirsebom, B. E. and Fladby, T. and Platt, F. and Blennow, K.}, title = {{Plasma phosphorylated-tau217 is increased in Niemann-Pick disease type C}}, journal = {Brain communications}, year = {2024}, doi = {10.1093/braincomms/fcae375}, pmid = {39502943}, url = {https://doi.org/10.1093/braincomms/fcae375} } @article{zhao2019-31026486, author = {Zhao, Y. and Xin, Y. and Meng, S. and He, Z. and Hu, W.}, title = {{Neurofilament light chain protein in neurodegenerative dementia: A systematic review and network meta-analysis}}, journal = {Neuroscience and biobehavioral reviews}, year = {2019}, doi = {10.1016/j.neubiorev.2019.04.014}, pmid = {31026486}, url = {https://doi.org/10.1016/j.neubiorev.2019.04.014} } @article{vanderende2020-32273328, author = {van der Ende, E. L. and Xiao, M. and Xu, D. and Poos, J. M. and Panman, J. L. and Jiskoot, L. C. and Meeter, L. H. and Dopper, E. G. and others}, title = {{Neuronal pentraxin 2: a synapse-derived CSF biomarker in genetic frontotemporal dementia}}, journal = {Journal of neurology, neurosurgery, and psychiatry}, year = {2020}, doi = {10.1136/jnnp-2019-322493}, pmid = {32273328}, url = {https://doi.org/10.1136/jnnp-2019-322493} } @article{kirmess2024-1b1b5bc0, author = {Kirmess, Kristopher M. and Eastwood, Stephanie and Wente-Roth, Traci L. and Irvin, Faith and Holubasch, Mary S. and Venkatesh, Venky and Fogelman, Ilana and Monane, Mark and Hanna, Lucy and Rabinovici, Gil D. and Siegel, Barry A. and Whitmer, Rachel A. and Apgar, Charles and Bateman, Randall J. and Holtzman, David M. and Irizarry, Michael and Verbel, David and Sachdev, Pallavi and Ito, Satoshi and Contois, John and Yarasheski, Kevin E. and Braunstein, Joel B. and Verghese, Philip B. and West, Tim}, title = {{Clinical validation of the PrecivityAD2 blood test: A mass spectrometry-based test with algorithm combining \%p-tau217 and Aβ42/40 ratio to identify presence of brain amyloid}}, journal = {Alzheimer's \& Dementia}, year = {2024} } @article{landau2015-25745095, author = {Landau, S. M. and Fero, A. and Baker, S. L. and Koeppe, R. and Mintun, M. and Chen, K. and Reiman, E. M. and Jagust, W. J.}, title = {{Measurement of longitudinal β-amyloid change with 18F-florbetapir PET and standardized uptake value ratios}}, journal = {Journal of nuclear medicine : official publication, Society of Nuclear Medicine}, year = {2015}, doi = {10.2967/jnumed.114.148981}, pmid = {25745095}, url = {https://doi.org/10.2967/jnumed.114.148981} } @article{mielke2021-34309632, author = {Mielke, M. M. and Frank, R. D. and Dage, J. L. and Jeromin, A. and Ashton, N. J. and Blennow, K. and Karikari, T. K. and Vanmechelen, E. and others}, title = {{Comparison of Plasma Phosphorylated Tau Species With Amyloid and Tau Positron Emission Tomography, Neurodegeneration, Vascular Pathology, and Cognitive Outcomes}}, journal = {JAMA neurology}, year = {2021}, doi = {10.1001/jamaneurol.2021.2293}, pmid = {34309632}, url = {https://doi.org/10.1001/jamaneurol.2021.2293} } @article{weston2017-29070659, author = {Weston, P. S. J. and Poole, T. and Ryan, N. S. and Nair, A. and Liang, Y. and Macpherson, K. and Druyeh, R. and Malone, I. B. and others}, title = {{Serum neurofilament light in familial Alzheimer disease: A marker of early neurodegeneration}}, journal = {Neurology}, year = {2017}, doi = {10.1212/wnl.0000000000004667}, pmid = {29070659}, url = {https://doi.org/10.1212/wnl.0000000000004667} } @article{illangala2021-33199433, author = {Illán-Gala, I. and Lleo, A. and Karydas, A. and Staffaroni, A. M. and Zetterberg, H. and Sivasankaran, R. and Grinberg, L. T. and Spina, S. and others}, title = {{Plasma Tau and Neurofilament Light in Frontotemporal Lobar Degeneration and Alzheimer Disease}}, journal = {Neurology}, year = {2021}, doi = {10.1212/wnl.0000000000011226}, pmid = {33199433}, url = {https://doi.org/10.1212/wnl.0000000000011226} } @article{li2024-38400792, author = {Li, Y. and Yen, D. and Hendrix, R. D. and Gordon, B. A. and Dlamini, S. and Barthélemy, N. R. and Aschenbrenner, A. J. and Henson, R. L. and others}, title = {{Timing of Biomarker Changes in Sporadic Alzheimer's Disease in Estimated Years from Symptom Onset}}, journal = {Annals of neurology}, year = {2024}, doi = {10.1002/ana.26891}, pmid = {38400792}, url = {https://doi.org/10.1002/ana.26891} } @article{santossantos2018-29309493, author = {Santos-Santos, M. A. and Rabinovici, G. D. and Iaccarino, L. and Ayakta, N. and Tammewar, G. and Lobach, I. and Henry, M. L. and Hubbard, I. and others}, title = {{Rates of Amyloid Imaging Positivity in Patients With Primary Progressive Aphasia}}, journal = {JAMA neurology}, year = {2018}, doi = {10.1001/jamaneurol.2017.4309}, pmid = {29309493}, url = {https://doi.org/10.1001/jamaneurol.2017.4309} } @article{josephmathurin2022-36151869, author = {Joseph-Mathurin, N. and Llibre-Guerra, J. J. and Li, Y. and McCullough, A. A. and Hofmann, C. and Wojtowicz, J. and Park, E. and Wang, G. and others}, title = {{Amyloid-Related Imaging Abnormalities in the DIAN-TU-001 Trial of Gantenerumab and Solanezumab: Lessons from a Trial in Dominantly Inherited Alzheimer Disease}}, journal = {Annals of neurology}, year = {2022}, doi = {10.1002/ana.26511}, pmid = {36151869}, url = {https://doi.org/10.1002/ana.26511} } @article{tangen2022-36028328, author = {Tangen, G. G. and Nilsson, M. H. and Stomrud, E. and Palmqvist, S. and Hansson, O.}, title = {{Spatial Navigation and Its Association With Biomarkers and Future Dementia in Memory Clinic Patients Without Dementia}}, journal = {Neurology}, year = {2022}, doi = {10.1212/wnl.0000000000201106}, pmid = {36028328}, url = {https://doi.org/10.1212/wnl.0000000000201106} } @article{lingler2018-30094328, author = {Lingler, J. H. and Roberts, J. S. and Kim, H. and Morris, J. L. and Hu, L. and Mattos, M. and McDade, E. and Lopez, O. L.}, title = {{Amyloid positron emission tomography candidates may focus more on benefits than risks of results disclosure}}, journal = {Alzheimer's \& dementia (Amsterdam, Netherlands)}, year = {2018}, doi = {10.1016/j.dadm.2018.05.003}, pmid = {30094328}, url = {https://doi.org/10.1016/j.dadm.2018.05.003} } @article{mengel2025-40247130, author = {Mengel, D. and Soter, E. and Ott, J. M. and Wacker, M. and Leyva, A. and Peters, O. and Hellmann-Regen, J. and Schneider, L. S. and others}, title = {{Blood biomarkers confirm subjective cognitive decline (SCD) as a distinct molecular and clinical stage within the NIA-AA framework of Alzheimer´s disease}}, journal = {Molecular psychiatry}, year = {2025}, doi = {10.1038/s41380-025-03021-0}, pmid = {40247130}, url = {https://doi.org/10.1038/s41380-025-03021-0} } @article{yun2025-39960728, author = {Yun, J. and Shin, D. and Lee, E. H. and Kim, J. P. and Ham, H. and Gu, Y. and Chun, M. Y. and Kang, S. H. and others}, title = {{Temporal Dynamics and Biological Variability of Alzheimer Biomarkers}}, journal = {JAMA neurology}, year = {2025}, doi = {10.1001/jamaneurol.2024.5263}, pmid = {39960728}, url = {https://doi.org/10.1001/jamaneurol.2024.5263} } @article{soldan2025-39724536, author = {Soldan, A. and Pettigrew, C. and Wang, J. and Albert, M. S. and Blennow, K. and Bittner, T. and Moghekar, A.}, title = {{Blood-Based Biomarkers and Risk of Onset of Mild Cognitive Impairment Over the Short and Long Term}}, journal = {Neurology}, year = {2025}, doi = {10.1212/wnl.0000000000210225}, pmid = {39724536}, url = {https://doi.org/10.1212/wnl.0000000000210225} } @article{gogniat2025-40561381, author = {Gogniat, M. A. and Khan, O. A. and Ratangee, B. and Bolton, C. J. and Zhang, P. and Liu, D. and Pechman, K. R. and Yates, A. and others}, title = {{Cross-Sectional and Longitudinal Associations of Neighborhood Disadvantage With Fluid Biomarkers of Neuroinflammation and Neurodegeneration}}, journal = {Neurology}, year = {2025}, doi = {10.1212/wnl.0000000000213770}, pmid = {40561381}, url = {https://doi.org/10.1212/wnl.0000000000213770} } @article{cousins2025-40801297, author = {Cousins, K. A. Q. and Korecka, M. and Wan, Y. and Vulaj, A. and Brown, C. and Tropea, T. F. and Lee, E. B. and Tosun, D. and Landau, S. M. and Okonkwo, O. C. and Mindt, M. R. and Weiner, M. W. and others}, title = {{Comparison of plasma p-tau217/Aβ42, p-tau217, and Aβ42/Aβ40 biomarkers by race to detect Alzheimer's disease}}, journal = {Alzheimer's \& Dementia}, year = {2025}, doi = {10.1002/alz.70469}, pmid = {40801297}, url = {https://doi.org/10.1002/alz.70469} } @article{jack2016-27371494, author = {Jack, C. R. and Bennett, D. A. and Blennow, K. and Carrillo, M. C. and Feldman, H. H. and Frisoni, G. B. and Hampel, H. and others}, title = {{A/T/N: An unbiased descriptive classification scheme for Alzheimer disease biomarkers}}, journal = {Neurology}, year = {2016}, doi = {10.1212/wnl.0000000000002923}, pmid = {27371494}, url = {https://doi.org/10.1212/wnl.0000000000002923} } @article{therriault2020-31860000, author = {Therriault, J. and Benedet, A. L. and Pascoal, T. A. and Mathotaarachchi, S. and Chamoun, M. and Savard, M. and Thomas, E. and Kang, M. S. and others}, title = {{Association of Apolipoprotein E ε4 With Medial Temporal Tau Independent of Amyloid-β}}, journal = {JAMA neurology}, year = {2020}, doi = {10.1001/jamaneurol.2019.4421}, pmid = {31860000}, url = {https://doi.org/10.1001/jamaneurol.2019.4421} } @article{fortea2018-30172624, author = {Fortea, J. and Carmona-Iragui, M. and Benejam, B. and Fernández, S. and Videla, L. and Barroeta, I. and Alcolea, D. and Pegueroles, J. and others}, title = {{Plasma and CSF biomarkers for the diagnosis of Alzheimer's disease in adults with Down syndrome: a cross-sectional study}}, journal = {The Lancet. Neurology}, year = {2018}, doi = {10.1016/s1474-4422(18)30285-0}, pmid = {30172624}, url = {https://doi.org/10.1016/s1474-4422(18)30285-0} } @article{ebenau2020-32522798, author = {Ebenau, J. L. and Timmers, T. and Wesselman, L. M. P. and Verberk, I. M. W. and Verfaillie, S. C. J. and Slot, R. E. R. and van Harten, A. C. and Teunissen, C. E. and others}, title = {{ATN classification and clinical progression in subjective cognitive decline: The SCIENCe project}}, journal = {Neurology}, year = {2020}, doi = {10.1212/wnl.0000000000009724}, pmid = {32522798}, url = {https://doi.org/10.1212/wnl.0000000000009724} } @article{bejanin2021-34228042, author = {Bejanin, A. and Iulita, M. F. and Vilaplana, E. and Carmona-Iragui, M. and Benejam, B. and Videla, L. and Barroeta, I. and Fernandez, S. and others}, title = {{Association of Apolipoprotein E ɛ4 Allele With Clinical and Multimodal Biomarker Changes of Alzheimer Disease in Adults With Down Syndrome}}, journal = {JAMA neurology}, year = {2021}, doi = {10.1001/jamaneurol.2021.1893}, pmid = {34228042}, url = {https://doi.org/10.1001/jamaneurol.2021.1893} } @article{steward2023-37930695, author = {Steward, A. and Biel, D. and Dewenter, A. and Roemer, S. and Wagner, F. and Dehsarvi, A. and Rathore, S. and Otero Svaldi, D. and others}, title = {{ApoE4 and Connectivity-Mediated Spreading of Tau Pathology at Lower Amyloid Levels}}, journal = {JAMA neurology}, year = {2023}, doi = {10.1001/jamaneurol.2023.4038}, pmid = {37930695}, url = {https://doi.org/10.1001/jamaneurol.2023.4038} } @article{janelidze2022-35789365, author = {Janelidze, S. and Christian, B. T. and Price, J. and Laymon, C. and Schupf, N. and Klunk, W. E. and Lott, I. and Silverman, W. and others}, title = {{Detection of Brain Tau Pathology in Down Syndrome Using Plasma Biomarkers}}, journal = {JAMA neurology}, year = {2022}, doi = {10.1001/jamaneurol.2022.1740}, pmid = {35789365}, url = {https://doi.org/10.1001/jamaneurol.2022.1740} } @article{long2022-35867858, author = {Long, J. M. and Coble, D. W. and Xiong, C. and Schindler, S. E. and Perrin, R. J. and Gordon, B. A. and Benzinger, T. L. S. and Grant, E. and others}, title = {{Preclinical Alzheimer's disease biomarkers accurately predict cognitive and neuropathological outcomes}}, journal = {Brain : a journal of neurology}, year = {2022}, doi = {10.1093/brain/awac250}, pmid = {35867858}, url = {https://doi.org/10.1093/brain/awac250} } @article{aslanyan2023-37379733, author = {Aslanyan, V. and Ortega, N. and Fenton, L. and Harrison, T. M. and Raman, R. and Mack, W. J. and Pa, J.}, title = {{Protective effects of sleep duration and physical activity on cognitive performance are influenced by β-amyloid and brain volume but not tau burden among cognitively unimpaired older adults}}, journal = {NeuroImage. Clinical}, year = {2023}, doi = {10.1016/j.nicl.2023.103460}, pmid = {37379733}, url = {https://doi.org/10.1016/j.nicl.2023.103460} } @article{martinoadami2024-39253733, author = {Martino-Adami, P. V. and Chatterjee, M. and Kleineidam, L. and Weyerer, S. and Bickel, H. and Wiese, B. and Riedel-Heller, S. G. and Scherer, M. and others}, title = {{Prognostic value of Alzheimer's disease plasma biomarkers in the oldest-old: a prospective primary care-based study}}, journal = {The Lancet regional health. Europe}, year = {2024}, doi = {10.1016/j.lanepe.2024.101030}, pmid = {39253733}, url = {https://doi.org/10.1016/j.lanepe.2024.101030} } @article{amariglio2024-39044492, author = {Amariglio, R. E. and Grill, J. D. and Rentz, D. M. and Marshall, G. A. and Donohue, M. C. and Liu, A. and Aisen, P. S. and Sperling, R. A.}, title = {{Longitudinal Trajectories of the Cognitive Function Index in the A4 Study}}, journal = {The journal of prevention of Alzheimer's disease}, year = {2024}, doi = {10.14283/jpad.2024.125}, pmid = {39044492}, url = {https://doi.org/10.14283/jpad.2024.125} } @article{trieu2025-41335440, author = {Trieu, C. and van Harten, A. C. and van Leeuwenstijn, M. S. S. A. and Schlüter, L. M. and Boonkamp, L. and Aladdin, A. and Sikkes, S. A. M. and van de Giessen, E. and others}, title = {{Longitudinal Blood-Based Biomarkers and Clinical Progression in Subjective Cognitive Decline}}, journal = {JAMA network open}, year = {2025}, doi = {10.1001/jamanetworkopen.2025.45862}, pmid = {41335440}, url = {https://doi.org/10.1001/jamanetworkopen.2025.45862} } @article{valletta2026-41996117, author = {Valletta, Martina and Vetrano, Davide Liborio and Qiu, Chengxuan and Canevelli, Marco and Miccoli, Edoardo and Andersson, Sarah Wamala and Fredolini, Claudia and Bruno, Giuseppe and others}, title = {{Anemia and Blood Biomarkers of Alzheimer Disease in Dementia Development}}, journal = {JAMA Network Open}, year = {2026}, doi = {10.1001/jamanetworkopen.2026.4029}, pmid = {41996117}, url = {https://doi.org/10.1001/jamanetworkopen.2026.4029} } @article{brickman2025-41269690, author = {Brickman, Adam M. and Muller, Chandra and Warren, John Robert and Grodsky, Eric and Kim, Soobin and Culbertson, Michael J. and Thyagarajan, Bharat and Manly, Jennifer J.}, title = {{Alzheimer Disease Blood Biomarker Concentrations Across Race and Ethnicity Groups in Middle-Aged Adults}}, journal = {JAMA Network Open}, year = {2025}, doi = {10.1001/jamanetworkopen.2025.45046}, pmid = {41269690}, url = {https://doi.org/10.1001/jamanetworkopen.2025.45046} } @article{jack2009-20083042, author = {Jack, Clifford R. and Knopman, David S. and Jagust, William J. and Shaw, Leslie M. and Aisen, Paul S. S. and Weiner, Michael Walter and Petersen, Ronald Carl and Trojanowski, John Q.}, title = {{Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade}}, journal = {The Lancet Neurology}, year = {2009}, doi = {10.1016/s1474-4422(09)70299-6}, pmid = {20083042}, url = {https://doi.org/10.1016/s1474-4422(09)70299-6} } @article{jack2013-23332364, author = {Jack, Clifford R. and Knopman, David S. and Jagust, William J. and Petersen, Ronald Carl and Weiner, Michael Walter and Aisen, Paul S. S. and Shaw, Leslie M. and Vemuri, Prashanthi and others}, title = {{Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers}}, journal = {The Lancet Neurology}, year = {2013}, doi = {10.1016/s1474-4422(12)70291-0}, pmid = {23332364}, url = {https://doi.org/10.1016/s1474-4422(12)70291-0} } @article{milaaloma2022-35953717, author = {Milà-Alomà, M. and Ashton, N. J. and Shekari, M. and Salvadó, G. and Ortiz-Romero, P. and Montoliu-Gaya, L. and Benedet, A. L. and Karikari, T. K. and others}, title = {{Plasma p-tau231 and p-tau217 as state markers of amyloid-β pathology in preclinical Alzheimer's disease}}, journal = {Nature medicine}, year = {2022}, doi = {10.1038/s41591-022-01925-w}, pmid = {35953717}, url = {https://doi.org/10.1038/s41591-022-01925-w} } @article{vandervelpen2019-31779690, author = {van der Velpen, V. and Teav, T. and Gallart-Ayala, H. and Mehl, F. and Konz, I. and Clark, C. and Oikonomidi, A. and Peyratout, G. and others}, title = {{Systemic and central nervous system metabolic alterations in Alzheimer's disease}}, journal = {Alzheimer's research \& therapy}, year = {2019}, doi = {10.1186/s13195-019-0551-7}, pmid = {31779690}, url = {https://doi.org/10.1186/s13195-019-0551-7} } @article{thijssen2022-35603139, author = {Thijssen, E. H. and Verberk, I. M. W. and Kindermans, J. and Abramian, A. and Vanbrabant, J. and Ball, A. J. and Pijnenburg, Y. and Lemstra, A. W. and others}, title = {{Differential diagnostic performance of a panel of plasma biomarkers for different types of dementia}}, journal = {Alzheimer's \& dementia (Amsterdam, Netherlands)}, year = {2022}, doi = {10.1002/dad2.12285}, pmid = {35603139}, url = {https://doi.org/10.1002/dad2.12285} } @article{niemantsverdriet2017-28869470, author = {Niemantsverdriet, E. and Ottoy, J. and Somers, C. and De Roeck, E. and Struyfs, H. and Soetewey, F. and Verhaeghe, J. and Van den Bossche, T. and others}, title = {{The Cerebrospinal Fluid Aβ1-42/Aβ1-40 Ratio Improves Concordance with Amyloid-PET for Diagnosing Alzheimer's Disease in a Clinical Setting}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2017}, doi = {10.3233/jad-170327}, pmid = {28869470}, url = {https://doi.org/10.3233/jad-170327} } @article{vanderende2019-31701893, author = {van der Ende, E. L. and Meeter, L. H. and Poos, J. M. and Panman, J. L. and Jiskoot, L. C. and Dopper, E. G. P. and Papma, J. M. and de Jong, F. J. and others}, title = {{Serum neurofilament light chain in genetic frontotemporal dementia: a longitudinal, multicentre cohort study}}, journal = {The Lancet. Neurology}, year = {2019}, doi = {10.1016/s1474-4422(19)30354-0}, pmid = {31701893}, url = {https://doi.org/10.1016/s1474-4422(19)30354-0} } @article{tian2025-40399764, author = {Tian, Xunyao and Zhu, Min and Ma, Yixun and Wang, Nan and Shi, Lin and Liu, Cuicui and Zhang, Heng and Tian, Na and others}, title = {{Physical and biopsychosocial frailty, cognitive phenotypes, and plasma biomarkers for Alzheimer's disease in Chinese older adults: A population-based study}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2025}, doi = {10.1002/alz.70303}, pmid = {40399764}, url = {https://doi.org/10.1002/alz.70303} } @article{cottez2026-42273887, author = {Cottez, Rosalie J and Peyrot, Clémence and Denis, Hélèna L and Tremblay, Cyntia and Loiselle, Andréanne and Dallaire-Théroux, Caroline and Filali-Mouhim, Ali and Hébert, Sébastien S and others}, title = {{Plasma p-tau markers, vascular factors, and cognitive decline in the CIMA-Q cohort}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2026}, doi = {10.1002/alz.71588}, pmid = {42273887}, url = {https://doi.org/10.1002/alz.71588} } @article{gonzales2021-33860071, author = {Gonzales, Mitzi M and Short, Meghan I and Satizabal, Claudia L and Bryant, Sid O' and Tracy, Russel P and Zare, Habil and Seshadri, Sudha}, title = {{Blood biomarkers for dementia in Hispanic and non-Hispanic White adults}}, journal = {Alzheimer's \& dementia (New York, N. Y.)}, year = {2021}, doi = {10.1002/trc2.12164}, pmid = {33860071}, url = {https://doi.org/10.1002/trc2.12164} } @article{shim2022-35585907, author = {Shim, YongSoo}, title = {{Clinical Application of Plasma Neurofilament Light Chain in a Memory Clinic: A Pilot Study}}, journal = {Dementia and neurocognitive disorders}, year = {2022}, doi = {10.12779/dnd.2022.21.2.59}, pmid = {35585907}, url = {https://doi.org/10.12779/dnd.2022.21.2.59} } @article{cousins2022-36215050, author = {Cousins, Katheryn A Q and Shaw, Leslie M and Chen-Plotkin, Alice and Wolk, David A and Van Deerlin, Vivianna M and Lee, Edward B and McMillan, Corey T and Grossman, Murray and others}, title = {{Distinguishing Frontotemporal Lobar Degeneration Tau From TDP-43 Using Plasma Biomarkers}}, journal = {JAMA neurology}, year = {2022}, doi = {10.1001/jamaneurol.2022.3265}, pmid = {36215050}, url = {https://doi.org/10.1001/jamaneurol.2022.3265} } @article{ally2023-37885919, author = {Ally, Madeline and Sugarman, Michael A and Zetterberg, Henrik and Blennow, Kaj and Ashton, Nicholas J and Karikari, Thomas K and Aparicio, Hugo J and Frank, Brandon and others}, title = {{Cross-sectional and longitudinal evaluation of plasma glial fibrillary acidic protein to detect and predict clinical syndromes of Alzheimer's disease}}, journal = {Alzheimer's \& dementia (Amsterdam, Netherlands)}, year = {2023}, doi = {10.1002/dad2.12492}, pmid = {37885919}, url = {https://doi.org/10.1002/dad2.12492} } @article{bai2022-36408096, author = {Bai, Jianhao and Wan, Zhongqi and Wang, Minli and Wu, Xue and Wang, Tianyu and Zhang, Yuanyuan and Xue, Yawen and Xu, Hong and others}, title = {{Association of cognitive function with Neurofilament light chain in the aqueous humor of human eye}}, journal = {Frontiers in aging neuroscience}, year = {2022}, doi = {10.3389/fnagi.2022.1027705}, pmid = {36408096}, url = {https://doi.org/10.3389/fnagi.2022.1027705} } @article{parker2022-34260706, author = {Parker, Margaret and White, Marissa and Casey, Cameron and Kunkel, David and Bo, Amber and Blennow, Kaj and Zetterberg, Henrik and Pearce, Robert A and others}, title = {{Cohort Analysis of the Association of Delirium Severity With Cerebrospinal Fluid Amyloid-Tau-Neurodegeneration Pathologies}}, journal = {The journals of gerontology. Series A, Biological sciences and medical sciences}, year = {2022}, doi = {10.1093/gerona/glab203}, pmid = {34260706}, url = {https://doi.org/10.1093/gerona/glab203} } @article{paoletti2023-37095141, author = {Paoletti, Federico Paolini and Gaetani, Lorenzo and Bellomo, Giovanni and Chipi, Elena and Salvadori, Nicola and Montanucci, Chiara and Mancini, Andrea and Filidei, Marta and others}, title = {{CSF neurochemical profile and cognitive changes in Parkinson's disease with mild cognitive impairment}}, journal = {NPJ Parkinson's disease}, year = {2023}, doi = {10.1038/s41531-023-00509-w}, pmid = {37095141}, url = {https://doi.org/10.1038/s41531-023-00509-w} } @article{castro2022-37231965, author = {Castro, Jesús Garcia and Del Sol, Helena Méndez and Fraga, Olaia Rodríguez and Barral, María Hernández and López, Soledad Serrano and García, Ana Frank and Montes, Ángel Martín}, title = {{CSF Aβ40 Levels Do Not Correlate with the Clinical Manifestations of Alzheimer's Disease}}, journal = {Neuro-degenerative diseases}, year = {2022}, doi = {10.1159/000530907}, pmid = {37231965}, url = {https://doi.org/10.1159/000530907} } @article{huang2022-36110426, author = {Huang, Ling-Chun and Chen, Ming-Hui and Chuu, Chih-Pin and Li, Kuan-Ying and Hour, Tzyh-Chyuan and Yang, Yuan-Han}, title = {{Plasma biomarkers and their correlation in adult children of parents with Alzheimer's disease}}, journal = {Frontiers in aging neuroscience}, year = {2022}, doi = {10.3389/fnagi.2022.977515}, pmid = {36110426}, url = {https://doi.org/10.3389/fnagi.2022.977515} } @article{villarreal2019-31401637, author = {Villarreal, Alcibiades E and Pérez-Lao, Ambar R and Oviedo, Diana C and Grajales, Shantal and Carreira, Maria B and Britton, Gabrielle B}, title = {{The Panama Aging Research Initiative Longitudinal Study}}, journal = {MEDICC review}, year = {2019}, doi = {10.37757/mr2019.v21.n2-3.10}, pmid = {31401637}, url = {https://doi.org/10.37757/mr2019.v21.n2-3.10} } @article{ashton2019-30626432, author = {Ashton, Nicholas James and Leuzy, Antoine and Lim, Yau Mun and Troakes, Claire and Hortobágyi, Tibor and Höglund, Kina and Aarsland, Dag and Lovestone, Simon and others}, title = {{Increased plasma neurofilament light chain concentration correlates with severity of post-mortem neurofibrillary tangle pathology and neurodegeneration}}, journal = {Acta Neuropathologica Communications}, year = {2019}, doi = {10.1186/s40478-018-0649-3}, pmid = {30626432}, url = {https://doi.org/10.1186/s40478-018-0649-3} } @article{thomas2021-2dde0399, author = {Thomas, Kelsey R. and Bangen, Katherine J. and Edmonds, Emily C. and Weigand, Alexandra J. and Walker, Kayla S. and Bondi, Mark W. and Galasko, Douglas R. and {Alzheimer's Disease Neuroimaging Initiative}}, title = {{Objective subtle cognitive decline and plasma phosphorylated tau181: Early markers of Alzheimer's disease‐related declines}}, journal = {Alzheimer's \& Dementia: Diagnosis, Assessment \& Disease Monitoring}, year = {2021}, doi = {10.1002/dad2.12238}, url = {https://doi.org/10.1002/dad2.12238} } @article{gu2024-38183363, author = {Gu, Y. and Honig, L. S. and Kang, M. S. and Bahl, A. and Sanchez, D. and Reyes-Dumeyer, D. and Manly, J. J. and Dage, J. L. and others}, title = {{Risk of Alzheimer's disease is associated with longitudinal changes in plasma biomarkers in the multi-ethnic Washington Heights-Hamilton Heights-Inwood Columbia Aging Project (WHICAP) cohort}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2024}, doi = {10.1002/alz.13652}, pmid = {38183363}, url = {https://doi.org/10.1002/alz.13652} } @article{lan2025-40550877, author = {Lan, G. and Wang, M. and Gonzalez-Ortiz, F. and Zhang, L. and Li, A. and Li, B. and Jiang, M. and Yang, J. and others}, title = {{Comprehensive evaluation of plasma tau biomarkers for detecting and monitoring Alzheimer's disease in a multicenter and multiethnic aging population}}, journal = {Nature aging}, year = {2025}, doi = {10.1038/s43587-025-00904-3}, pmid = {40550877}, url = {https://doi.org/10.1038/s43587-025-00904-3} } @article{tang2014-24817210, author = {Tang, W. and Huang, Q. and Yao, Y. Y. and Wang, Y. and Wu, Y. L. and Wang, Z. Y.}, title = {{Does CSF p-tau181 help to discriminate Alzheimer's disease from other dementias and mild cognitive impairment? A meta-analysis of the literature}}, journal = {Journal of neural transmission (Vienna, Austria : 1996)}, year = {2014}, doi = {10.1007/s00702-014-1226-y}, pmid = {24817210}, url = {https://doi.org/10.1007/s00702-014-1226-y} } @article{nair2023-37377978, author = {Nair, A. K. and Van Hulle, C. A. and Bendlin, B. B. and Zetterberg, H. and Blennow, K. and Wild, N. and Kollmorgen, G. and Suridjan, I. and others}, title = {{Impact of asthma on the brain: evidence from diffusion MRI, CSF biomarkers and cognitive decline}}, journal = {Brain communications}, year = {2023}, doi = {10.1093/braincomms/fcad180}, pmid = {37377978}, url = {https://doi.org/10.1093/braincomms/fcad180} } @article{lin2025-39877979, author = {Lin, Y. S. and Kwon, H. S. and Lee, W. J. and Hwang, M. and Jeong, J. H. and Koh, S. H. and Choi, S. H. and Fuh, J. L.}, title = {{Cross-cultural validation of plasma p-tau217 and p-tau181 as precision biomarkers for amyloid PET positivity: An East Asian study in Taiwan and Korea}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2025}, doi = {10.1002/alz.14565}, pmid = {39877979}, url = {https://doi.org/10.1002/alz.14565} } @article{martinezdubarbie2024-39559871, author = {Martínez-Dubarbie, F. and Guerra-Ruiz, A. and López-García, S. and Lage, C. and Fernández-Matarrubia, M. and Infante, J. and Pozueta-Cantudo, A. and García-Martínez, M. and others}, title = {{Diagnostic Accuracy of Plasma p-tau217 for Detecting Pathological Cerebrospinal Fluid Changes in Cognitively Unimpaired Subjects Using the Lumipulse Platform}}, journal = {The journal of prevention of Alzheimer's disease}, year = {2024}, doi = {10.14283/jpad.2024.152}, pmid = {39559871}, url = {https://doi.org/10.14283/jpad.2024.152} } @article{lanterorodriguez2025-40095069, author = {Lantero-Rodriguez, J. and Montoliu-Gaya, L. and Ashton, N. J. and Pola, I. and Therriault, J. and Rahmouni, N. and Brum, W. S. and Servaes, S. and others}, title = {{Biofluid-based staging of Alzheimer's disease}}, journal = {Acta neuropathologica}, year = {2025}, doi = {10.1007/s00401-025-02863-w}, pmid = {40095069}, url = {https://doi.org/10.1007/s00401-025-02863-w} } @article{backstrom2015-26258692, author = {Bäckström, D. C. and Eriksson Domellöf, M. and Linder, J. and Olsson, B. and Öhrfelt, A. and Trupp, M. and Zetterberg, H. and Blennow, K. and others}, title = {{Cerebrospinal Fluid Patterns and the Risk of Future Dementia in Early, Incident Parkinson Disease}}, journal = {JAMA neurology}, year = {2015}, doi = {10.1001/jamaneurol.2015.1449}, pmid = {26258692}, url = {https://doi.org/10.1001/jamaneurol.2015.1449} } @article{pahlke2025-41193403, author = {Pahlke, S. and Kahale, L. A. and Mahinrad, S. and Sousa-Pinto, B. and Vieira, R. J. and McAteer, M. B. and Claessen, T. and Contador, J. and Hofmann, A. and Kuchenbecker, L. A. and others}, title = {{Blood-based biomarkers for detecting Alzheimer's disease pathology in cognitively impaired individuals within specialized care settings: A systematic review and meta-analysis}}, journal = {Alzheimer's \& Dementia}, year = {2025}, doi = {10.1002/alz.70828}, pmid = {41193403}, url = {https://doi.org/10.1002/alz.70828} } @article{jack2015-25775353, author = {Jack, C. R. and Wiste, H. J. and Weigand, S. D. and Knopman, D. S. and Vemuri, P. and Mielke, M. M. and Lowe, V. and Senjem, M. L. and others}, title = {{Age, Sex, and APOE ε4 Effects on Memory, Brain Structure, and β-Amyloid Across the Adult Life Span}}, journal = {JAMA neurology}, year = {2015}, doi = {10.1001/jamaneurol.2014.4821}, pmid = {25775353}, url = {https://doi.org/10.1001/jamaneurol.2014.4821} } @article{sprecher2017-28679595, author = {Sprecher, K. E. and Koscik, R. L. and Carlsson, C. M. and Zetterberg, H. and Blennow, K. and Okonkwo, O. C. and Sager, M. A. and Asthana, S. and others}, title = {{Poor sleep is associated with CSF biomarkers of amyloid pathology in cognitively normal adults}}, journal = {Neurology}, year = {2017}, doi = {10.1212/wnl.0000000000004171}, pmid = {28679595}, url = {https://doi.org/10.1212/wnl.0000000000004171} } @article{roberts2014-24652830, author = {Roberts, R. O. and Knopman, D. S. and Cha, R. H. and Mielke, M. M. and Pankratz, V. S. and Boeve, B. F. and Kantarci, K. and Geda, Y. E. and others}, title = {{Diabetes and elevated hemoglobin A1c levels are associated with brain hypometabolism but not amyloid accumulation}}, journal = {Journal of nuclear medicine : official publication, Society of Nuclear Medicine}, year = {2014}, doi = {10.2967/jnumed.113.132647}, pmid = {24652830}, url = {https://doi.org/10.2967/jnumed.113.132647} } @article{quiroz2020-32470423, author = {Quiroz, Y. T. and Zetterberg, H. and Reiman, E. M. and Chen, Y. and Su, Y. and Fox-Fuller, J. T. and Garcia, G. and Villegas, A. and others}, title = {{Plasma neurofilament light chain in the presenilin 1 E280A autosomal dominant Alzheimer's disease kindred: a cross-sectional and longitudinal cohort study}}, journal = {The Lancet. Neurology}, year = {2020}, doi = {10.1016/s1474-4422(20)30137-x}, pmid = {32470423}, url = {https://doi.org/10.1016/s1474-4422(20)30137-x} } @article{collij2022-35292558, author = {Collij, L. E. and Salvadó, G. and Wottschel, V. and Mastenbroek, S. E. and Schoenmakers, P. and Heeman, F. and Aksman, L. and Wink, A. M. and others}, title = {{Spatial-Temporal Patterns of β-Amyloid Accumulation: A Subtype and Stage Inference Model Analysis}}, journal = {Neurology}, year = {2022}, doi = {10.1212/wnl.0000000000200148}, pmid = {35292558}, url = {https://doi.org/10.1212/wnl.0000000000200148} } @article{rojas2018-29282336, author = {Rojas, J. C. and Bang, J. and Lobach, IV. and Tsai, R. M. and Rabinovici, G. D. and Miller, B. L. and Boxer, A. L. and {AL-108-231 Investigators}}, title = {{CSF neurofilament light chain and phosphorylated tau 181 predict disease progression in PSP}}, journal = {Neurology}, year = {2018}, doi = {10.1212/wnl.0000000000004859}, pmid = {29282336}, url = {https://doi.org/10.1212/wnl.0000000000004859} } @article{schindler2021-34504028, author = {Schindler, S. E. and Li, Y. and Buckles, V. D. and Gordon, B. A. and Benzinger, T. L. S. and Wang, G. and Coble, D. and Klunk, W. E. and others}, title = {{Predicting Symptom Onset in Sporadic Alzheimer Disease With Amyloid PET}}, journal = {Neurology}, year = {2021}, doi = {10.1212/wnl.0000000000012775}, pmid = {34504028}, url = {https://doi.org/10.1212/wnl.0000000000012775} } @article{young2022-35435938, author = {Young, C. B. and Winer, JR. and Younes, K. and Cody, K. A. and Betthauser, T. J. and Johnson, S. C. and Schultz, A. and Sperling, R. A. and others}, title = {{Divergent Cortical Tau Positron Emission Tomography Patterns Among Patients With Preclinical Alzheimer Disease}}, journal = {JAMA neurology}, year = {2022}, doi = {10.1001/jamaneurol.2022.0676}, pmid = {35435938}, url = {https://doi.org/10.1001/jamaneurol.2022.0676} } @article{cicognola2023-37137722, author = {Cicognola, C. and Mattsson-Carlgren, N. and van Westen, D. and Zetterberg, H. and Blennow, K. and Palmqvist, S. and Ahmadi, K. and Strandberg, O. and others}, title = {{Associations of CSF PDGFRβ With Aging, Blood-Brain Barrier Damage, Neuroinflammation, and Alzheimer Disease Pathologic Changes}}, journal = {Neurology}, year = {2023}, doi = {10.1212/wnl.0000000000207358}, pmid = {37137722}, url = {https://doi.org/10.1212/wnl.0000000000207358} } @article{hofmann2024-39557867, author = {Hofmann, A. and Häsler, L. M. and Lambert, M. and Kaeser, S. A. and Gräber-Sultan, S. and Obermüller, U. and Kuder-Buletta, E. and la Fougere, C. and others}, title = {{Comparative neurofilament light chain trajectories in CSF and plasma in autosomal dominant Alzheimer's disease}}, journal = {Nature communications}, year = {2024}, doi = {10.1038/s41467-024-52937-8}, pmid = {39557867}, url = {https://doi.org/10.1038/s41467-024-52937-8} } @article{zeltzer2025-40720133, author = {Zeltzer, E. and Schonhaut, D. R. and Mundada, N. S. and Blazhenets, G. and Soleimani-Meigooni, D. N. and Cho, H. and Ranasinghe, K. G. and Windon, C. and others}, title = {{Concordance Between Amyloid-PET Quantification and Real-World Visual Reads}}, journal = {JAMA neurology}, year = {2025}, doi = {10.1001/jamaneurol.2025.2218}, pmid = {40720133}, url = {https://doi.org/10.1001/jamaneurol.2025.2218} } @article{selmagonzalez2025-40472304, author = {Selma-Gonzalez, J. and Rubio-Guerra, S. and García-Castro, J. and Vera-Campuzano, E. and Sala, I. and Sánchez-Saudinós, M. B. and Zhu, N. and Arranz, J. and others}, title = {{Association of Plasma Phosphorylated Tau 217 With Clinical Deterioration Across Alzheimer Disease Stages}}, journal = {Neurology}, year = {2025}, doi = {10.1212/wnl.0000000000213769}, pmid = {40472304}, url = {https://doi.org/10.1212/wnl.0000000000213769} } @article{vanderveere2024-38986053, author = {van der Veere, P. J. and Hoogland, J. and Visser, L. N. C. and Van Harten, A. C. and Rhodius-Meester, H. F. and Sikkes, S. A. M. and Venkatraghavan, V. and Barkhof, F. and others}, title = {{Predicting Cognitive Decline in Amyloid-Positive Patients With Mild Cognitive Impairment or Mild Dementia}}, journal = {Neurology}, year = {2024}, doi = {10.1212/wnl.0000000000209605}, pmid = {38986053}, url = {https://doi.org/10.1212/wnl.0000000000209605} } @article{kim2025-40042844, author = {Kim, S. A. and Shin, D. and Ham, H. and Kim, Y. and Gu, Y. and Kim, H. J. and Na, D. L. and Zetterberg, H. and others}, title = {{Physical Activity, Alzheimer Plasma Biomarkers, and Cognition}}, journal = {JAMA network open}, year = {2025}, doi = {10.1001/jamanetworkopen.2025.0096}, pmid = {40042844}, url = {https://doi.org/10.1001/jamanetworkopen.2025.0096} } @article{honig2024-38377442, author = {Hönig, M. and Altomare, D. and Caprioglio, C. and Collij, L. and Barkhof, F. and Van Berckel, B. and Scheltens, P. and Farrar, G. and others}, title = {{Association Between Years of Education and Amyloid Burden in Patients With Subjective Cognitive Decline, MCI, and Alzheimer Disease}}, journal = {Neurology}, year = {2024}, doi = {10.1212/wnl.0000000000208053}, pmid = {38377442}, url = {https://doi.org/10.1212/wnl.0000000000208053} } @article{davidson2026-41109840, author = {Davidson, M. H. and Szarek, M. and Scheltens, P. and Vijverberg, E. and Hsieh, A. and Ditmarsch, M. and Kling, D. and Curcio, D. and others}, title = {{Effect of obicetrapib, a potent cholesteryl ester transfer protein inhibitor, on p-tau217 levels in patients with cardiovascular disease}}, journal = {The journal of prevention of Alzheimer's disease}, year = {2026}, doi = {10.1016/j.tjpad.2025.100394}, pmid = {41109840}, url = {https://doi.org/10.1016/j.tjpad.2025.100394} } @article{delrieu2023-37872582, author = {Delrieu, J. and Vellas, B. and Guyonnet, S. and Cantet, C. and Ovod, V. and Li, Y. and Bollinger, J. and Bateman, R. and others}, title = {{Cognitive impact of multidomain intervention and omega 3 according to blood Aβ42/40 ratio: a subgroup analysis from the randomized MAPT trial}}, journal = {Alzheimer's research \& therapy}, year = {2023}, doi = {10.1186/s13195-023-01325-3}, pmid = {37872582}, url = {https://doi.org/10.1186/s13195-023-01325-3} } @article{yim2025-40829110, author = {Yim, Sohyun and Park, Seongbeom and Lim, Kyoungyoon and Kang, Heekyung and Shin, Daeun and Jo, Hyunjin and Jang, Hyemin and Weiner, Michael Walter and others}, title = {{Integrating MRI Volume and Plasma p-Tau217 for Amyloid Risk Stratification in Early-Stage Alzheimer Disease}}, journal = {Neurology}, year = {2025}, doi = {10.1212/wnl.0000000000213954}, pmid = {40829110}, url = {https://doi.org/10.1212/wnl.0000000000213954} } @article{karlsson2025-41051312, author = {Karlsson, Linda and Janelidze, Shorena and Barthélemy, Nicolas R. and Horie, Kanta and Therriault, Joseph and Gaetani, Lorenzo and Bellomo, Giovanni and Schindler, Suzanne Elizabeth and others}, title = {{Reference proteins to improve Core 1 and Core 2 Alzheimer’s disease CSF and plasma biomarkers}}, journal = {Brain}, year = {2025}, doi = {10.1093/brain/awaf375}, pmid = {41051312}, url = {https://doi.org/10.1093/brain/awaf375} } @article{kim2026-41804841, author = {Kim, Jun Pyo and Song, Minku and Cho, Minyoung and Lee, Hyunwoo and Jung, Sang-Hyuk and Lim, Soohyun and Kim, Chanhee and Jang, Beomjin and others}, title = {{Genetic architecture of plasma pTau217 and related biomarkers in Alzheimer's disease via genome-wide association studies}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2026}, doi = {10.1002/alz.71275}, pmid = {41804841}, url = {https://doi.org/10.1002/alz.71275} } @article{smith2026-41963316, author = {Smith, Alena M and Lorkiewicz, Sara A and Arslan, Burak and Montoliu-Gaya, Laia and Ashton, Nicholas J and Wilson, Edward N and Alcolea, Daniel and Rodríguez-Baz, Íñigo and others}, title = {{Plasma phosphorylated tau 217 detects amyloid-β in neuronal synuclein disease}}, journal = {NPJ Parkinson's disease}, year = {2026}, doi = {10.1038/s41531-026-01341-8}, pmid = {41963316}, url = {https://doi.org/10.1038/s41531-026-01341-8} } @article{moon2025-40544093, author = {Moon, Hasom and Chen, Xi and {Alzheimer’s Disease Neuroimaging Initiative}}, title = {{Plasma p-tau217 predicting brain-wide tau accumulation in preclinical AD}}, journal = {The journal of prevention of Alzheimer's disease}, year = {2025}, doi = {10.1016/j.tjpad.2025.100252}, pmid = {40544093}, url = {https://doi.org/10.1016/j.tjpad.2025.100252} } @article{malotaux2025-40588692, author = {Malotaux, Vincent and Ashton, Nicholas J and Öhrfelt, Annika and Chen, Yinghua and Su, Yi and Garcia-Ospina, Gloria and Guzman-Martínez, Claudia and Villegas-Lanau, Andres and others}, title = {{Plasma p-tau231 in the presenilin 1 E280A autosomal dominant Alzheimer's disease kindred: A cross-sectional and longitudinal cohort study}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2025}, doi = {10.1002/alz.70421}, pmid = {40588692}, url = {https://doi.org/10.1002/alz.70421} } @article{yan2026-41312760, author = {Yan, Shijun and Sahoo, Anis and Zerenner, Tanja and Marek, Kenneth and Sommerauer, Michael and Oertel, Wolfgang and Hu, Michele T and Tofaris, George K}, title = {{Serum p-tau217 Is a Prognostic Indicator of Cognitive Impairment in Idiopathic REM Sleep Behavior Disorder}}, journal = {Annals of neurology}, year = {2026}, doi = {10.1002/ana.78109}, pmid = {41312760}, url = {https://doi.org/10.1002/ana.78109} } @article{zhu2021-34893073, author = {Zhu, Nuole and Santos-Santos, Miguel and Illán-Gala, Ignacio and Montal, Victor and Estellés, Teresa and Barroeta, Isabel and Altuna, Miren and Arranz, Javier and others}, title = {{Plasma glial fibrillary acidic protein and neurofilament light chain for the diagnostic and prognostic evaluation of frontotemporal dementia}}, journal = {Translational neurodegeneration}, year = {2021}, doi = {10.1186/s40035-021-00275-w}, pmid = {34893073}, url = {https://doi.org/10.1186/s40035-021-00275-w} } @article{staffaroni2022-36138153, author = {Staffaroni, Adam M and Quintana, Melanie and Wendelberger, Barbara and Heuer, Hilary W and Russell, Lucy L and Cobigo, Yann and Wolf, Amy and Goh, Sheng-Yang Matt and others}, title = {{Temporal order of clinical and biomarker changes in familial frontotemporal dementia}}, journal = {Nature medicine}, year = {2022}, doi = {10.1038/s41591-022-01942-9}, pmid = {36138153}, url = {https://doi.org/10.1038/s41591-022-01942-9} } @article{freudenberghua2025-40659842, author = {Freudenberg-Hua, Yun and Giliberto, Luca and d'Abramo, Cristina and Li, Wentian and Ma, Yilong and Goate, Alison and Koppel, Jeremy}, title = {{Differential associations of APOE and TREM2 variants with glial fibrillary acidic protein and neurofilament light in plasma of UK Biobank participants support distinct disease mechanisms}}, journal = {Molecular psychiatry}, year = {2025}, doi = {10.1038/s41380-025-03098-7}, pmid = {40659842}, url = {https://doi.org/10.1038/s41380-025-03098-7} } @article{mazzeo2024-37723371, author = {Mazzeo, Salvatore and Ingannato, Assunta and Giacomucci, Giulia and Bagnoli, Silvia and Cavaliere, Arianna and Moschini, Valentina and Balestrini, Juri and Morinelli, Carmen and others}, title = {{The role of plasma neurofilament light chain and glial fibrillary acidic protein in subjective cognitive decline and mild cognitive impairment}}, journal = {Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology}, year = {2024}, doi = {10.1007/s10072-023-07065-4}, pmid = {37723371}, url = {https://doi.org/10.1007/s10072-023-07065-4} } @article{pauley2026-42558640, author = {Pauley, Meghan E and Coughlan, Christina and Dong, Fran and Bucca, Brian and Tanner, Bailey and Chartier-Logan, Catherine and Shapiro, Allison L B and Snell-Bergeon, Janet K}, title = {{Type 1 diabetes is associated with higher plasma levels of biomarkers of neurodegeneration and neuroinflammation}}, journal = {Frontiers in immunology}, year = {2026}, doi = {10.3389/fimmu.2026.1860993}, pmid = {42558640}, url = {https://doi.org/10.3389/fimmu.2026.1860993} } @article{jang2025-39907189, author = {Jang, Hyemin and Shin, Daeun and Yoo, Heejin and Zetterberg, Henrik and Blennow, Kaj and Gonzalez-Ortiz, Fernando and Ashton, Nicholas J and Day, Theresa A and others}, title = {{Differential roles of Alzheimer's disease plasma biomarkers in stepwise biomarker-guided diagnostics}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2025}, doi = {10.1002/alz.14526}, pmid = {39907189}, url = {https://doi.org/10.1002/alz.14526} } @article{gotze2024-39427171, author = {Götze, Karl and Vrillon, Agathe and Dumurgier, Julien and Indart, Sandrine and Sanchez-Ortiz, Marta and Slimi, Hela and Raynaud-Simon, Agathe and Cognat, Emmanuel and others}, title = {{Plasma neurofilament light chain as prognostic marker of cognitive decline in neurodegenerative diseases, a clinical setting study}}, journal = {Alzheimer's research \& therapy}, year = {2024}, doi = {10.1186/s13195-024-01593-7}, pmid = {39427171}, url = {https://doi.org/10.1186/s13195-024-01593-7} } @article{tang2024-38664843, author = {Tang, Rongxiang and Buchholz, Erik and Dale, Anders M and Rissman, Robert A and Fennema-Notestine, Christine and Gillespie, Nathan A and Hagler, Donald J and Lyons, Michael J and others}, title = {{Associations of plasma neurofilament light chain with cognition and neuroimaging measures in community-dwelling early old age men}}, journal = {Alzheimer's research \& therapy}, year = {2024}, doi = {10.1186/s13195-024-01464-1}, pmid = {38664843}, url = {https://doi.org/10.1186/s13195-024-01464-1} } @article{pettigrew2025-40151521, author = {Pettigrew, Corinne and Soldan, Anja and Wang, Jiangxia and Hohman, Timothy and Dumitrescu, Logan and Albert, Marilyn and Blennow, Kaj and Bittner, Tobias and others}, title = {{Plasma biomarker trajectories: Impact of AD genetic risk and clinical progression}}, journal = {Alzheimer's \& dementia (Amsterdam, Netherlands)}, year = {2025}, doi = {10.1002/dad2.70081}, pmid = {40151521}, url = {https://doi.org/10.1002/dad2.70081} } @article{vogelgsang2024-38940303, author = {Vogelgsang, Jonathan and Hansen, Niels and Stark, Melina and Wagner, Michael and Klafki, Hans and Morgado, Barbara Marcos and Jahn-Brodmann, Anke and Schott, Björn and others}, title = {{Plasma amyloid beta X-42/X-40 ratio and cognitive decline in suspected early and preclinical Alzheimer's disease}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2024}, doi = {10.1002/alz.13909}, pmid = {38940303}, url = {https://doi.org/10.1002/alz.13909} } @article{xiong2024-38956096, author = {Xiong, Chengjie and Luo, Jingqin and Wolk, David A and Shaw, Leslie M and Roberson, Erik D and Murchison, Charles F and Henson, Rachel L and Benzinger, Tammie L S and others}, title = {{Baseline levels and longitudinal changes in plasma Aβ42/40 among Black and white individuals}}, journal = {Nature communications}, year = {2024}, doi = {10.1038/s41467-024-49859-w}, pmid = {38956096}, url = {https://doi.org/10.1038/s41467-024-49859-w} } @article{knorr2022-34728295, author = {Knorr, Ulla and Simonsen, Anja Hviid and Jensen, Camilla Steen and Zetterberg, Henrik and Blennow, Kaj and Akhøj, Morten and Forman, Julie and Hasselbalch, Steen Gregers and others}, title = {{Alzheimer's disease related biomarkers in bipolar disorder - A longitudinal one-year case-control study}}, journal = {Journal of affective disorders}, year = {2022}, doi = {10.1016/j.jad.2021.10.074}, pmid = {34728295}, url = {https://doi.org/10.1016/j.jad.2021.10.074} } @article{guzmanvelez2024-39748841, author = {Guzmán-Vélez, Edmarie and Rivera-Hernández, Angelys and Fabrega, Sofia and Oliveira, Gabriel and Martínez, Jairo E and Baena, Ana and Picard, Glen and Lopera, Francisco and others}, title = {{Relationship between physical activity and biomarkers of pathology and neuroinflammation in preclinical autosomal-dominant Alzheimer's disease}}, journal = {Alzheimer's \& dementia (New York, N. Y.)}, year = {2024}, doi = {10.1002/trc2.70003}, pmid = {39748841}, url = {https://doi.org/10.1002/trc2.70003} } @article{liu2026-42158847, author = {Liu, Caiyan and Cheng, Anqi and Zou, Yinxi and Wang, Hebo and Ai, Zhibing and Wu, Shiwen and Liu, Linwen and Li, Mingli and others}, title = {{Plasma biomarkers of neurodegeneration and neuroinflammation in intracranial atherosclerotic disease}}, journal = {Brain communications}, year = {2026}, doi = {10.1093/braincomms/fcag125}, pmid = {42158847}, url = {https://doi.org/10.1093/braincomms/fcag125} } @article{winston2023-36710683, author = {Winston, Charisse N and Langford, Oliver and Levin, Natalie and Raman, Rema and Yarasheski, Kevin and West, Tim and Abdel-Latif, Sara and Donohue, Michael and others}, title = {{Evaluation of Blood-Based Plasma Biomarkers as Potential Markers of Amyloid Burden in Preclinical Alzheimer's Disease}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2023}, doi = {10.3233/jad-221118}, pmid = {36710683}, url = {https://doi.org/10.3233/jad-221118} } @article{silvaspinola2026-41535718, author = {Silva-Spínola, Anuschka and Durães, João and de Oliveira, João Pedro Guedes and Tábuas-Pereira, Miguel and Lima, Marisa and de Mendonça, Alexandre and Santana, Isabel and Baldeiras, Inês}, title = {{Plasma p-tau217, quantified by the fully automated LUMIPULSE G platform, outperforms p-tau181 in predicting amyloid pathology in cognitive complaints patients}}, journal = {Scientific reports}, year = {2026}, doi = {10.1038/s41598-025-34241-7}, pmid = {41535718}, url = {https://doi.org/10.1038/s41598-025-34241-7} } @article{schindler2024-38866966, author = {Schindler, S. E. and Galasko, D. and Pereira, A. C. and Rabinovici, G. D. and Salloway, S. and Suárez-Calvet, M. and Khachaturian, A. S. and Mielke, M. M. and Udeh-Momoh, C. and Weiss, J. and Batrla, R. and Bozeat, S. and others}, title = {{Acceptable performance of blood biomarker tests of amyloid pathology - recommendations from the Global CEO Initiative on Alzheimer's Disease}}, journal = {Nature Reviews Neurology}, year = {2024}, doi = {10.1038/s41582-024-00977-5}, pmid = {38866966}, url = {https://doi.org/10.1038/s41582-024-00977-5} } @article{piura2025-40476540, author = {Piura, Y. D. and Figdore, D. J. and Lachner, C. and Bornhorst, J. and Algeciras-Schimnich, A. and Graff-Radford, N. R. and Day, G. S.}, title = {{Diagnostic performance of plasma p-tau217 and Aβ42/40 biomarkers in the outpatient memory clinic}}, journal = {Alzheimer's \& Dementia}, year = {2025}, doi = {10.1002/alz.70316}, pmid = {40476540}, url = {https://doi.org/10.1002/alz.70316} } @article{schindler2019-31371569, author = {Schindler, S. E. and Bollinger, J. G. and Ovod, V. and Mawuenyega, K. G. and Li, Y. and Gordon, B. A. and Holtzman, D. M. and Morris, J. C. and others}, title = {{High-precision plasma β-amyloid 42/40 predicts current and future brain amyloidosis}}, journal = {Neurology}, year = {2019}, doi = {10.1212/wnl.0000000000008081}, pmid = {31371569}, url = {https://doi.org/10.1212/wnl.0000000000008081} } @article{taddei2023-37812432, author = {Taddei, R. N. and Perbet, R. and Mate de Gerando, A. and Wiedmer, A. E. and Sanchez-Mico, M. and Connors Stewart, T. and Gaona, A. and Melloni, A. and others}, title = {{Tau Oligomer-Containing Synapse Elimination by Microglia and Astrocytes in Alzheimer Disease}}, journal = {JAMA neurology}, year = {2023}, doi = {10.1001/jamaneurol.2023.3530}, pmid = {37812432}, url = {https://doi.org/10.1001/jamaneurol.2023.3530} } @article{iaccarino2021-33252608, author = {Iaccarino, L. and La Joie, R. and Lesman-Segev, O. H. and Lee, E. and Hanna, L. and Allen, I. E. and Hillner, B. E. and Siegel, B. A. and others}, title = {{Association Between Ambient Air Pollution and Amyloid Positron Emission Tomography Positivity in Older Adults With Cognitive Impairment}}, journal = {JAMA neurology}, year = {2021}, doi = {10.1001/jamaneurol.2020.3962}, pmid = {33252608}, url = {https://doi.org/10.1001/jamaneurol.2020.3962} } @article{hajjar2022-36201209, author = {Hajjar, I. and Yang, Z. and Okafor, M. and Liu, C. and Waligorska, T. and Goldstein, F. C. and Shaw, L. M.}, title = {{Association of Plasma and Cerebrospinal Fluid Alzheimer Disease Biomarkers With Race and the Role of Genetic Ancestry, Vascular Comorbidities, and Neighborhood Factors}}, journal = {JAMA network open}, year = {2022}, doi = {10.1001/jamanetworkopen.2022.35068}, pmid = {36201209}, url = {https://doi.org/10.1001/jamanetworkopen.2022.35068} } @article{fagan2021-34302786, author = {Fagan, A. M. and Henson, R. L. and Li, Y. and Boerwinkle, A. H. and Xiong, C. and Bateman, R. J. and Goate, A. and Ances, B. M. and others}, title = {{Comparison of CSF biomarkers in Down syndrome and autosomal dominant Alzheimer's disease: a cross-sectional study}}, journal = {The Lancet. Neurology}, year = {2021}, doi = {10.1016/s1474-4422(21)00139-3}, pmid = {34302786}, url = {https://doi.org/10.1016/s1474-4422(21)00139-3} } @article{chiao2019-29777003, author = {Chiao, P. and Bedell, B. J. and Avants, B. and Zijdenbos, A. P. and Grand'Maison, M. and O'Neill, P. and O'Gorman, J. and Chen, T. and others}, title = {{Impact of Reference and Target Region Selection on Amyloid PET SUV Ratios in the Phase 1b PRIME Study of Aducanumab}}, journal = {Journal of nuclear medicine : official publication, Society of Nuclear Medicine}, year = {2019}, doi = {10.2967/jnumed.118.209130}, pmid = {29777003}, url = {https://doi.org/10.2967/jnumed.118.209130} } @article{kivisakk2022-35800899, author = {Kivisäkk, P. and Magdamo, C. and Trombetta, B. A. and Noori, A. and Kuo, Y. K. E. and Chibnik, L. B. and Carlyle, B. C. and Serrano-Pozo, A. and others}, title = {{Plasma biomarkers for prognosis of cognitive decline in patients with mild cognitive impairment}}, journal = {Brain communications}, year = {2022}, doi = {10.1093/braincomms/fcac155}, pmid = {35800899}, url = {https://doi.org/10.1093/braincomms/fcac155} } @article{kang2025-40343697, author = {Kang, S. H. and Lee, E. H. and Kim, Y. J. and Jang, H. and Shin, D. and Zetterberg, H. and Blennow, K. and Gonzalez-Ortiz, F. and others}, title = {{Cerebral Amyloid Angiopathy and Downstream Alzheimer Disease Plasma Biomarkers}}, journal = {JAMA network open}, year = {2025}, doi = {10.1001/jamanetworkopen.2025.8842}, pmid = {40343697}, url = {https://doi.org/10.1001/jamanetworkopen.2025.8842} } @article{cai2025-40622710, author = {Cai, Yue Qin and Fang, Lili and Yang, Jie and Zhou, Xin Yu and Liu, Lin and Li, Anqi and Sun, Pan and Lan, Guoyu and others}, title = {{Higher Educational Attainment and Accelerated Tau Accumulation in Alzheimer Disease}}, journal = {JAMA Neurology}, year = {2025}, doi = {10.1001/jamaneurol.2025.1801}, pmid = {40622710}, url = {https://doi.org/10.1001/jamaneurol.2025.1801} } @article{simren2021-33491853, author = {Simrén, J. and Leuzy, A. and Karikari, T. K. and Hye, A. and Benedet, A. L. and Lantero-Rodriguez, J. and Mattsson-Carlgren, N. and Schöll, M. and others}, title = {{The diagnostic and prognostic capabilities of plasma biomarkers in Alzheimer's disease}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2021}, doi = {10.1002/alz.12283}, pmid = {33491853}, url = {https://doi.org/10.1002/alz.12283} } @article{gonzalezortiz2024-37975513, author = {Gonzalez-Ortiz, F. and Ferreira, P. C. L. and González-Escalante, A. and Montoliu-Gaya, L. and Ortiz-Romero, P. and Kac, P. R. and Turton, M. and Kvartsberg, H. and others}, title = {{A novel ultrasensitive assay for plasma p-tau217: Performance in individuals with subjective cognitive decline and early Alzheimer's disease}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2024}, doi = {10.1002/alz.13525}, pmid = {37975513}, url = {https://doi.org/10.1002/alz.13525} } @article{riekse2006-17183151, author = {Riekse, R. G. and Li, G. and Petrie, E. C. and Leverenz, J. B. and Vavrek, D. and Vuletic, S. and Albers, J. J. and Montine, T. J. and others}, title = {{Effect of statins on Alzheimer's disease biomarkers in cerebrospinal fluid}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2006}, doi = {10.3233/jad-2006-10408}, pmid = {17183151}, url = {https://doi.org/10.3233/jad-2006-10408} } @article{chatterjee2021-33431793, author = {Chatterjee, P. and Pedrini, S. and Stoops, E. and Goozee, K. and Villemagne, V. L. and Asih, P. R. and Verberk, I. M. W. and Dave, P. and others}, title = {{Plasma glial fibrillary acidic protein is elevated in cognitively normal older adults at risk of Alzheimer's disease}}, journal = {Translational psychiatry}, year = {2021}, doi = {10.1038/s41398-020-01137-1}, pmid = {33431793}, url = {https://doi.org/10.1038/s41398-020-01137-1} } @article{meeter2016-27606344, author = {Meeter, L. H. and Dopper, E. G. and Jiskoot, L. C. and Sanchez-Valle, R. and Graff, C. and Benussi, L. and Ghidoni, R. and Pijnenburg, Y. A. and others}, title = {{Neurofilament light chain: a biomarker for genetic frontotemporal dementia}}, journal = {Annals of clinical and translational neurology}, year = {2016}, doi = {10.1002/acn3.325}, pmid = {27606344}, url = {https://doi.org/10.1002/acn3.325} } @article{gonzalezortiz2023-36572122, author = {Gonzalez-Ortiz, F. and Turton, M. and Kac, P. R. and Smirnov, D. and Premi, E. and Ghidoni, R. and Benussi, L. and Cantoni, V. and others}, title = {{Brain-derived tau: a novel blood-based biomarker for Alzheimer's disease-type neurodegeneration}}, journal = {Brain : a journal of neurology}, year = {2023}, doi = {10.1093/brain/awac407}, pmid = {36572122}, url = {https://doi.org/10.1093/brain/awac407} } @article{alves2010-20547614, author = {Alves, G. and Brønnick, K. and Aarsland, D. and Blennow, K. and Zetterberg, H. and Ballard, C. and Kurz, M. W. and Andreasson, U. and others}, title = {{CSF amyloid-beta and tau proteins, and cognitive performance, in early and untreated Parkinson's disease: the Norwegian ParkWest study}}, journal = {Journal of neurology, neurosurgery, and psychiatry}, year = {2010}, doi = {10.1136/jnnp.2009.199950}, pmid = {20547614}, url = {https://doi.org/10.1136/jnnp.2009.199950} } @article{iulita2023-37056479, author = {Iulita, M. F. and Bejanin, A. and Vilaplana, E. and Carmona-Iragui, M. and Benejam, B. and Videla, L. and Barroeta, I. and Fernández, S. and others}, title = {{Association of biological sex with clinical outcomes and biomarkers of Alzheimer's disease in adults with Down syndrome}}, journal = {Brain communications}, year = {2023}, doi = {10.1093/braincomms/fcad074}, pmid = {37056479}, url = {https://doi.org/10.1093/braincomms/fcad074} } @article{oh2023-38057571, author = {Oh, H. S. and Rutledge, J. and Nachun, D. and Pálovics, R. and Abiose, O. and Moran-Losada, P. and Channappa, D. and Urey, D. Y. and others}, title = {{Organ aging signatures in the plasma proteome track health and disease}}, journal = {Nature}, year = {2023}, doi = {10.1038/s41586-023-06802-1}, pmid = {38057571}, url = {https://doi.org/10.1038/s41586-023-06802-1} } @article{keshavan2021-33479777, author = {Keshavan, A. and Pannee, J. and Karikari, T. K. and Rodriguez, J. L. and Ashton, N. J. and Nicholas, J. M. and Cash, D. M. and Coath, W. and others}, title = {{Population-based blood screening for preclinical Alzheimer's disease in a British birth cohort at age 70}}, journal = {Brain : a journal of neurology}, year = {2021}, doi = {10.1093/brain/awaa403}, pmid = {33479777}, url = {https://doi.org/10.1093/brain/awaa403} } @article{shir2022-35252538, author = {Shir, D. and Graff-Radford, J. and Hofrenning, E. I. and Lesnick, T. G. and Przybelski, S. A. and Lowe, V. J. and Knopman, D. S. and Petersen, R. C. and others}, title = {{Association of plasma glial fibrillary acidic protein (GFAP) with neuroimaging of Alzheimer's disease and vascular pathology}}, journal = {Alzheimer's \& dementia (Amsterdam, Netherlands)}, year = {2022}, doi = {10.1002/dad2.12291}, pmid = {35252538}, url = {https://doi.org/10.1002/dad2.12291} } @article{zhang2023-37009461, author = {Zhang, B. and Zhang, C. and Wang, Y. and Chen, L. and Qiao, Y. and Peng, D. and {Alzheimer’s Disease Neuroimaging Initiative}}, title = {{Effect of renal function on the diagnostic performance of plasma biomarkers for Alzheimer's disease}}, journal = {Frontiers in aging neuroscience}, year = {2023}, doi = {10.3389/fnagi.2023.1150510}, pmid = {37009461}, url = {https://doi.org/10.3389/fnagi.2023.1150510} } @article{park2023-37121979, author = {Park, J. C. and Lim, H. and Byun, M. S. and Yi, D. and Byeon, G. and Jung, G. and Kim, Y. K. and Lee, D. Y. and others}, title = {{Sex differences in the progression of glucose metabolism dysfunction in Alzheimer's disease}}, journal = {Experimental \& molecular medicine}, year = {2023}, doi = {10.1038/s12276-023-00993-3}, pmid = {37121979}, url = {https://doi.org/10.1038/s12276-023-00993-3} } @article{molinahenry2024-38629508, author = {Molina-Henry, D. P. and Raman, R. and Liu, A. and Langford, O. and Johnson, K. and Shum, L. K. and Glover, C. M. and Dhadda, S. and others}, title = {{Racial and ethnic differences in plasma biomarker eligibility for a preclinical Alzheimer's disease trial}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2024}, doi = {10.1002/alz.13803}, pmid = {38629508}, url = {https://doi.org/10.1002/alz.13803} } @article{obryant2022-34057802, author = {O'Bryant, S. E. and Zhang, F. and Petersen, M. and Hall, JR. and Johnson, L. A. and Yaffe, K. and Mason, D. and Braskie, M. and others}, title = {{A blood screening tool for detecting mild cognitive impairment and Alzheimer's disease among community-dwelling Mexican Americans and non-Hispanic Whites: A method for increasing representation of diverse populations in clinical research}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2022}, doi = {10.1002/alz.12382}, pmid = {34057802}, url = {https://doi.org/10.1002/alz.12382} } @article{thomas2022-35318733, author = {Thomas, A. J. and Hamilton, C. A. and Heslegrave, A. and Barker, S. and Durcan, R. and Lawley, S. and Barnett, N. and Lett, D. and others}, title = {{A Longitudinal Study of Plasma pTau181 in Mild Cognitive Impairment with Lewy Bodies and Alzheimer's Disease}}, journal = {Movement disorders : official journal of the Movement Disorder Society}, year = {2022}, doi = {10.1002/mds.28994}, pmid = {35318733}, url = {https://doi.org/10.1002/mds.28994} } @article{palmqvist2025-40205199, author = {Palmqvist, S. and Warmenhoven, N. and Anastasi, F. and Pilotto, A. and Janelidze, S. and Tideman, P. and Stomrud, E. and Mattsson-Carlgren, N. and others}, title = {{Plasma phospho-tau217 for Alzheimer's disease diagnosis in primary and secondary care using a fully automated platform}}, journal = {Nature medicine}, year = {2025}, doi = {10.1038/s41591-025-03622-w}, pmid = {40205199}, url = {https://doi.org/10.1038/s41591-025-03622-w} } @article{gleason2018-29125485, author = {Gleason, C. E. and Norton, D. and Anderson, E. D. and Wahoske, M. and Washington, D. T. and Umucu, E. and Koscik, R. L. and Dowling, N. M. and others}, title = {{Cognitive Variability Predicts Incident Alzheimer's Disease and Mild Cognitive Impairment Comparable to a Cerebrospinal Fluid Biomarker}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2018}, doi = {10.3233/jad-170498}, pmid = {29125485}, url = {https://doi.org/10.3233/jad-170498} } @article{pandey2025-39743558, author = {Pandey, N. and Yang, Z. and Cieza, B. and Reyes-Dumeyer, D. and Kang, M. S. and Montesinos, R. and Soto-Añari, M. and Custodio, N. and others}, title = {{Plasma phospho-tau217 as a predictive biomarker for Alzheimer's disease in a large south American cohort}}, journal = {Alzheimer's research \& therapy}, year = {2025}, doi = {10.1186/s13195-024-01655-w}, pmid = {39743558}, url = {https://doi.org/10.1186/s13195-024-01655-w} } @article{kwon2025-40044785, author = {Kwon, H. S. and Hwang, M. and Koh, S. H. and Choi, S. H. and Lee, J. H. and Kim, H. J. and Park, S. H. and Park, H. H. and others}, title = {{Comparison of plasma p-tau217 and p-tau181 in predicting amyloid positivity and prognosis among Korean memory clinic patients}}, journal = {Scientific reports}, year = {2025}, doi = {10.1038/s41598-025-90232-8}, pmid = {40044785}, url = {https://doi.org/10.1038/s41598-025-90232-8} } @article{nabizadeh2022-35015198, author = {Nabizadeh, F. and Pourhamzeh, M. and Khani, S. and Rezaei, A. and Ranjbaran, F. and Deravi, N. and ADNI}, title = {{Plasma phosphorylated-tau181 levels reflect white matter microstructural changes across Alzheimer's disease progression}}, journal = {Metabolic brain disease}, year = {2022}, doi = {10.1007/s11011-022-00908-7}, pmid = {35015198}, url = {https://doi.org/10.1007/s11011-022-00908-7} } @article{benussi2020-32611664, author = {Benussi, A. and Karikari, T. K. and Ashton, N. and Gazzina, S. and Premi, E. and Benussi, L. and Ghidoni, R. and Rodriguez, J. L. and others}, title = {{Diagnostic and prognostic value of serum NfL and p-Tau181 in frontotemporal lobar degeneration}}, journal = {Journal of neurology, neurosurgery, and psychiatry}, year = {2020}, doi = {10.1136/jnnp-2020-323487}, pmid = {32611664}, url = {https://doi.org/10.1136/jnnp-2020-323487} } @article{sehrawat2025-e4bc0f72, author = {Sehrawat, Anuradha and Zeng, Xuemei and Abrahamson, Eric E. and Deek, Rebecca A. and Gogola, Alexandra and Kamboh, M. Ilyas and Pascoal, Tharick A. and Villemagne, Victor L. and Lopez, Oscar L. and Ikonomovic, Milos D. and Snitz, Beth E. and Cohen, Ann D. and Karikari, Thomas K.}, title = {{Pittsburgh plasma p-tau217: Classification accuracies for autosomal dominant and sporadic Alzheimer's disease in the community}}, journal = {Alzheimer's \& Dementia}, year = {2025} } @article{mattssoncarlgren2022-35173015, author = {Mattsson-Carlgren, N. and Grinberg, L. T. and Boxer, A. and Ossenkoppele, R. and Jonsson, M. and Seeley, W. and Ehrenberg, A. and Spina, S. and others}, title = {{Cerebrospinal Fluid Biomarkers in Autopsy-Confirmed Alzheimer Disease and Frontotemporal Lobar Degeneration}}, journal = {Neurology}, year = {2022}, doi = {10.1212/wnl.0000000000200040}, pmid = {35173015}, url = {https://doi.org/10.1212/wnl.0000000000200040} } @article{alcolea2017-28592456, author = {Alcolea, D. and Vilaplana, E. and Suárez-Calvet, M. and Illán-Gala, I. and Blesa, R. and Clarimón, J. and Lladó, A. and Sánchez-Valle, R. and others}, title = {{CSF sAPPβ, YKL-40, and neurofilament light in frontotemporal lobar degeneration}}, journal = {Neurology}, year = {2017}, doi = {10.1212/wnl.0000000000004088}, pmid = {28592456}, url = {https://doi.org/10.1212/wnl.0000000000004088} } @article{leuzy2021-34493616, author = {Leuzy, A. and Janelidze, S. and Mattsson-Carlgren, N. and Palmqvist, S. and Jacobs, D. and Cicognola, C. and Stomrud, E. and Vanmechelen, E. and others}, title = {{Comparing the Clinical Utility and Diagnostic Performance of CSF P-Tau181, P-Tau217, and P-Tau231 Assays}}, journal = {Neurology}, year = {2021}, doi = {10.1212/wnl.0000000000012727}, pmid = {34493616}, url = {https://doi.org/10.1212/wnl.0000000000012727} } @article{sevigny2016-26885819, author = {Sevigny, J. and Suhy, J. and Chiao, P. and Chen, T. and Klein, G. and Purcell, D. and Oh, J. and Verma, A. and others}, title = {{Amyloid PET Screening for Enrichment of Early-Stage Alzheimer Disease Clinical Trials: Experience in a Phase 1b Clinical Trial}}, journal = {Alzheimer disease and associated disorders}, year = {2016}, doi = {10.1097/wad.0000000000000144}, pmid = {26885819}, url = {https://doi.org/10.1097/wad.0000000000000144} } @article{brickman2018-30217936, author = {Brickman, A. M. and Tosto, G. and Gutierrez, J. and Andrews, H. and Gu, Y. and Narkhede, A. and Rizvi, B. and Guzman, V. and others}, title = {{An MRI measure of degenerative and cerebrovascular pathology in Alzheimer disease}}, journal = {Neurology}, year = {2018}, doi = {10.1212/wnl.0000000000006310}, pmid = {30217936}, url = {https://doi.org/10.1212/wnl.0000000000006310} } @article{fink2020-32340038, author = {Fink, H. A. and Linskens, E. J. and Silverman, P. C. and McCarten, JR. and Hemmy, L. S. and Ouellette, J. M. and Greer, N. L. and Wilt, T. J. and others}, title = {{Accuracy of Biomarker Testing for Neuropathologically Defined Alzheimer Disease in Older Adults With Dementia}}, journal = {Annals of internal medicine}, year = {2020}, doi = {10.7326/m19-3888}, pmid = {32340038}, url = {https://doi.org/10.7326/m19-3888} } @article{dark2025-39889254, author = {Dark, Heather E. and Shafer, Andrea T. and Cordon, Jenifer and An, Yang and Lewis, Alexandria and Moghekar, Abhay and Landman, Bennett A. and Resnick, Susan M. and others}, title = {{Association of Plasma Biomarkers of Alzheimer Disease and Neurodegeneration With Longitudinal Intra-Network Functional Brain Connectivity}}, journal = {Neurology}, year = {2025}, doi = {10.1212/wnl.0000000000210271}, pmid = {39889254}, url = {https://doi.org/10.1212/wnl.0000000000210271} } @article{sewell2026-41980229, author = {Sewell, Kelsey R. and Solis‐Urra, Patricio and Huang, Haiqing and Karikari, Thomas K. and Grove, George and Kramer, Arthur F. and McAuley, Edward and Burns, Jeffrey Murray and others}, title = {{Cognitive and Brain Reserve as Modifiers of Early Alzheimer Disease–Related Cognitive Vulnerability}}, journal = {Neurology}, year = {2026}, doi = {10.1212/wnl.0000000000214833}, pmid = {41980229}, url = {https://doi.org/10.1212/wnl.0000000000214833} } @article{brown2025-41396614, author = {Brown, Christopher Andrew and Mundada, Nidhi S. and Cousins, Katheryn A Q and Sadeghpour, Niyousha and Lyu, Xueying and McGrew, Emily and Korecka, Magdalena and Chen‐Plotkin, Alice S. and others}, title = {{Evaluation of Copathology and Clinical Trajectories in Individuals With Tau-Clinical Mismatch}}, journal = {JAMA Neurology}, year = {2025}, doi = {10.1001/jamaneurol.2025.4974}, pmid = {41396614}, url = {https://doi.org/10.1001/jamaneurol.2025.4974} } @article{ray2007-17934472, author = {Ray, Sandip and Britschgi, Markus and Herbert, Charles and Takeda‐Uchimura, Yoshiko and Boxer, Adam L. and Blennow, Kaj and Friedman, Leah and Galasko, Douglas R and Jutel, Marek and Karydas, Anna and Kaye, Jeffrey Alan and Leszek, Jerzy and Miller, Bruce L. and Minthon, Lennart and Quinn, Joseph F. and Rabinovici, Gil D. and Robinson, William H. and Sabbagh, Marwan Noel and So, Yuen T. and Sparks, D Larry and Tabaton, Massimo and Tinklenberg, Jared R. and Yesavage, Jerome Albert and Tibshirani, Robert John and Wyss‐Coray, Tony}, title = {{Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins}}, journal = {Nature Medicine}, year = {2007}, doi = {10.1038/nm1653}, pmid = {17934472}, url = {https://doi.org/10.1038/nm1653} } @article{aburumeileh2025-40044663, author = {Abu-Rumeileh, S. and Scholle, L. and Mensch, A. and Großkopf, H. and Ratti, A. and Kölsch, A. and Stoltenburg-Didinger, G. and Conrad, J. and others}, title = {{Phosphorylated tau 181 and 217 are elevated in serum and muscle of patients with amyotrophic lateral sclerosis}}, journal = {Nature communications}, year = {2025}, doi = {10.1038/s41467-025-57144-7}, pmid = {40044663}, url = {https://doi.org/10.1038/s41467-025-57144-7} } @article{pilotto2025-39679606, author = {Pilotto, Andrea and Quaresima, Virginia and Trasciatti, Chiara and Tolassi, Chiara and Bertoli, Diego and Mordenti, Cristina and Galli, Alice and Rizzardi, Andrea and others}, title = {{Plasma p-tau217 in Alzheimer's disease: Lumipulse and ALZpath SIMOA head-to-head comparison}}, journal = {Brain : a journal of neurology}, year = {2025}, doi = {10.1093/brain/awae368}, pmid = {39679606}, url = {https://doi.org/10.1093/brain/awae368} } @article{benina2026-41562409, author = {Benina, Natalya and Buitrago, Luna and De Simone, Francesca I and Radwan, Rachel R and Miller, M Craig and Martin, Katie and Dickson, Diana and Ho, Sara and others}, title = {{Plasma pTau 217/β-amyloid 1-42 ratio for enhanced accuracy and reduced uncertainty in detecting amyloid pathology}}, journal = {Brain : a journal of neurology}, year = {2026}, doi = {10.1093/brain/awag001}, pmid = {41562409}, url = {https://doi.org/10.1093/brain/awag001} } @article{piura2026-42619350, author = {Piura, Yoav D and Aduen, Paula A and Schecter, Leah and Jain, Manoj K and Algeciras-Schimnich, Alicia and Figdore, Daniel J and Bornhorst, Joshua and Petersen, Ronald C and others}, title = {{Optimized plasma p-tau217 and p-tau217/Aβ42 cutoffs enhance detection of pre-clinical Alzheimer's disease across diverse participants}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2026}, doi = {10.1002/alz.71763}, pmid = {42619350}, url = {https://doi.org/10.1002/alz.71763} } @article{giacomucci2026-41700306, author = {Giacomucci, Giulia and Tabbì, Silvia Maria Rita and Ingannato, Assunta and Bagnoli, Silvia and Padiglioni, Sonia and Crucitti, Chiara and Sensi, Chiara and Sanesi, Serena and others}, title = {{Refining Alzheimer's disease biological diagnosis with plasma biomarkers: Resolving p-tau217 "gray zone" with p-tau181 integration}}, journal = {Alzheimer's \& dementia (Amsterdam, Netherlands)}, year = {2026}, doi = {10.1002/dad2.70285}, pmid = {41700306}, url = {https://doi.org/10.1002/dad2.70285} } @article{oberlin2026-42151104, author = {Oberlin, Lauren E and Solis-Urra, Patricio and Sewell, Kelsey R and Collins, Audrey M and Kang, Chaeryon and Huang, Haiqing and Grove, George and Wan, Lu and others}, title = {{Physical activity, aerobic fitness, and AD blood biomarkers: The IGNITE study}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2026}, doi = {10.1002/alz.71484}, pmid = {42151104}, url = {https://doi.org/10.1002/alz.71484} } @article{moghekar2026-42418465, author = {Moghekar, Abhay R and Rock, James A and Mohs, Richard C and Hansson, Oskar and Stomrud, Erik and Palmqvist, Sebastian and Mattsson-Carlgren, Niklas and Johnson, Sterling C and others}, title = {{Multicenter validation of plasma p-tau217/ amyloid beta 1-42 ratio in symptomatic Alzheimer's disease}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2026}, doi = {10.1002/alz.71644}, pmid = {42418465}, url = {https://doi.org/10.1002/alz.71644} } @article{lee2025-39535473, author = {Lee, Eun Hye and Kang, Sung Hoon and Shin, Daeun and Kim, Young Ju and Zetterberg, Henrik and Blennow, Kaj and Gonzalez-Ortiz, Fernando and Ashton, Nicholas J and others}, title = {{Plasma Alzheimer's disease biomarker variability: Amyloid-independent and amyloid-dependent factors}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2025}, doi = {10.1002/alz.14368}, pmid = {39535473}, url = {https://doi.org/10.1002/alz.14368} } @article{beydoun2023-37257406, author = {Beydoun, May A and Hooten, Nicole Noren and Beydoun, Hind A and Weiss, Jordan and Maldonado, Ana I and Katzel, Leslie I and Davatzikos, Christos and Gullapalli, Rao P and others}, title = {{Plasma neurofilament light and brain volumetric outcomes among middle-aged urban adults}}, journal = {Neurobiology of aging}, year = {2023}, doi = {10.1016/j.neurobiolaging.2023.04.013}, pmid = {37257406}, url = {https://doi.org/10.1016/j.neurobiolaging.2023.04.013} } @article{subramanian2025-40982223, author = {Subramanian, Manju L and Sampani, Konstantina and Ness, Steven and Tuz-Zahra, Fatima and Alluri, Sreevardhan and Chen, Xuejing and Siegel, Nicole H and Aytan, Nurgul and others}, title = {{Biomarkers for Alzheimer's disease are upregulated in patients with diabetic retinopathy}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2025}, doi = {10.1177/13872877251378759}, pmid = {40982223}, url = {https://doi.org/10.1177/13872877251378759} } @article{liguori2025-40488440, author = {Liguori, Claudio and Fernandes, Mariana and Zatti, Cinzia and Carpi, Matteo and Tolassi, Chiara and Testone, Greta and Cirillo, Flavia and Antonucci, Matteo and others}, title = {{Plasma NfL, GFAP, and pTau181 in patients with isolated REM sleep behavior disorder}}, journal = {Sleep}, year = {2025}, doi = {10.1093/sleep/zsaf163}, pmid = {40488440}, url = {https://doi.org/10.1093/sleep/zsaf163} } @article{sun2020-32310173, author = {Sun, Yan and Tan, Lin and Xu, Wei and Wang, Zuo-Teng and Hu, Hao and Li, Jie-Qiong and Dong, Qiang and Tan, Lan and others}, title = {{Plasma Neurofilament Light and Longitudinal Progression of White Matter Hyperintensity in Elderly Persons Without Dementia}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2020}, doi = {10.3233/jad-200022}, pmid = {32310173}, url = {https://doi.org/10.3233/jad-200022} } @article{oconnor2021-33892504, author = {O'Connor, Antoinette and Pannee, Josef and Poole, Teresa and Arber, Charles and Portelius, Erik and Swift, Imogen J and Heslegrave, Amanda J and Abel, Emily and others}, title = {{Plasma amyloid-β ratios in autosomal dominant Alzheimer's disease: the influence of genotype}}, journal = {Brain : a journal of neurology}, year = {2021}, doi = {10.1093/brain/awab166}, pmid = {33892504}, url = {https://doi.org/10.1093/brain/awab166} } @article{dage2023-37491668, author = {Dage, Jeffrey L and Eloyan, Ani and Thangarajah, Maryanne and Hammers, Dustin B and Fagan, Anne M and Gray, Julia D and Schindler, Suzanne E and Snoddy, Casey and others}, title = {{Cerebrospinal fluid biomarkers in the Longitudinal Early-onset Alzheimer's Disease Study}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2023}, doi = {10.1002/alz.13399}, pmid = {37491668}, url = {https://doi.org/10.1002/alz.13399} } @article{zhong2022-35871345, author = {Zhong, Shuang and Zhao, Bing and Ma, Ya-Hui and Sun, Yan and Zhao, Yong-Li and Liu, Wen-Hui and Ou, Ya-Nan and Dong, Qiang and others}, title = {{Associations of Physical Activity with Alzheimer's Disease Pathologies and Cognition: The CABLE Study}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2022}, doi = {10.3233/jad-220389}, pmid = {35871345}, url = {https://doi.org/10.3233/jad-220389} } @article{eriksson2024-38939101, author = {Eriksson, Cecilia Magdalena and Kirsebom, Bjørn-Eivind and Espenes, Ragna and Siafarikas, Nikias and Waterloo, Knut and Rongve, Arvid and Selnes, Per and Aarsland, Dag and others}, title = {{Depressive Symptoms Are Not Associated with Predementia Cerebrospinal Fluid Amyloid Pathology}}, journal = {Dementia and geriatric cognitive disorders extra}, year = {2024}, doi = {10.1159/000539284}, pmid = {38939101}, url = {https://doi.org/10.1159/000539284} } @article{figdore2024-38304322, author = {Figdore, Daniel J and Wiste, Heather J and Bornhorst, Joshua A and Bateman, Randall J and Li, Yan and Graff-Radford, Jonathan and Knopman, David S and Vemuri, Prashanthi and others}, title = {{Performance of the Lumipulse plasma Aβ42/40 and pTau181 immunoassays in the detection of amyloid pathology}}, journal = {Alzheimer's \& dementia (Amsterdam, Netherlands)}, year = {2024}, doi = {10.1002/dad2.12545}, pmid = {38304322}, url = {https://doi.org/10.1002/dad2.12545} } @article{cecchetti2024-39174818, author = {Cecchetti, Giordano and Agosta, Federica and Rugarli, Giulia and Spinelli, Edoardo Gioele and Ghirelli, Alma and Zavarella, Matteo and Bottale, Ilaria and Orlandi, Francesca and others}, title = {{Diagnostic accuracy of automated Lumipulse plasma pTau-217 in Alzheimer's disease: a real-world study}}, journal = {Journal of neurology}, year = {2024}, doi = {10.1007/s00415-024-12631-7}, pmid = {39174818}, url = {https://doi.org/10.1007/s00415-024-12631-7} } @article{ritchie2026-42719535, author = {Ritchie, Craig and Hortsch, Sayuri and Quijano-Rubio, Clara and Menzel, Patrick and Kirste, Imke and Caley, David and Burke, Anna D and Rowe, Christopher C and others}, title = {{Elecsys pT181p immunoassay: Clinical performance for ruling out amyloid pathology}}, journal = {Alzheimer's \& dementia (Amsterdam, Netherlands)}, year = {2026}, doi = {10.1002/dad2.70439}, pmid = {42719535}, url = {https://doi.org/10.1002/dad2.70439} } @article{li2023-37204806, author = {Li, Melody and Li, Yan and Schindler, Suzanne E and Yen, Daniel and Sutcliffe, Siobhan and Babulal, Ganesh M and Benzinger, Tammie L S and Lenze, Eric J and others}, title = {{Design and feasibility of an Alzheimer's disease blood test study in a diverse community-based population}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2023}, doi = {10.1002/alz.13125}, pmid = {37204806}, url = {https://doi.org/10.1002/alz.13125} } @article{eratne2024-39369278, author = {Eratne, Dhamidhu and Kang, Matthew J Y and Lewis, Courtney and Dang, Christa and Malpas, Charles B and Keem, Michael and Grewal, Jasleen and Marinov, Vladimir and others}, title = {{Plasma and CSF neurofilament light chain distinguish neurodegenerative from primary psychiatric conditions in a clinical setting}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2024}, doi = {10.1002/alz.14278}, pmid = {39369278}, url = {https://doi.org/10.1002/alz.14278} } @article{deek2026-c113f7bd, author = {Deek, Rebecca A. and Balogun, Wasiu G. and Zeng, Xuemei and Triana-Baltzer, Gallen and Pascoal, Tharick A. and Kolb, Hartmuth C. and Snitz, Beth and Cohen, Ann D. and Karikari, Thomas K.}, title = {{Head-to-head comparison of plasma p-tau217 immunoassays for incipient Alzheimer's disease in community cohorts}}, journal = {Alzheimer's Research \& Therapy}, year = {2026} } @article{jack2012-22488240, author = {Jack, C. R. and Knopman, D. S. and Weigand, S. D. and Wiste, H. J. and Vemuri, P. and Lowe, V. and Kantarci, K. and Gunter, J. L. and others}, title = {{An operational approach to National Institute on Aging-Alzheimer's Association criteria for preclinical Alzheimer disease}}, journal = {Annals of neurology}, year = {2012}, doi = {10.1002/ana.22628}, pmid = {22488240}, url = {https://doi.org/10.1002/ana.22628} } @article{janelidze2016-27042676, author = {Janelidze, S. and Zetterberg, H. and Mattsson, N. and Palmqvist, S. and Vanderstichele, H. and Lindberg, O. and van Westen, D. and Stomrud, E. and others}, title = {{CSF Aβ42/Aβ40 and Aβ42/Aβ38 ratios: better diagnostic markers of Alzheimer disease}}, journal = {Annals of clinical and translational neurology}, year = {2016}, doi = {10.1002/acn3.274}, pmid = {27042676}, url = {https://doi.org/10.1002/acn3.274} } @article{jack2013-23446680, author = {Jack, C. R. and Wiste, H. J. and Lesnick, T. G. and Weigand, S. D. and Knopman, D. S. and Vemuri, P. and Pankratz, V. S. and Senjem, M. L. and others}, title = {{Brain β-amyloid load approaches a plateau}}, journal = {Neurology}, year = {2013}, doi = {10.1212/wnl.0b013e3182840bbe}, pmid = {23446680}, url = {https://doi.org/10.1212/wnl.0b013e3182840bbe} } @article{lajoie2021-33262228, author = {La Joie, R. and Visani, A. V. and Lesman-Segev, O. H. and Baker, S. L. and Edwards, L. and Iaccarino, L. and Soleimani-Meigooni, D. N. and Mellinger, T. and others}, title = {{Association of APOE4 and Clinical Variability in Alzheimer Disease With the Pattern of Tau- and Amyloid-PET}}, journal = {Neurology}, year = {2021}, doi = {10.1212/wnl.0000000000011270}, pmid = {33262228}, url = {https://doi.org/10.1212/wnl.0000000000011270} } @article{ramanan2023-37580163, author = {Ramanan, V. K. and Graff-Radford, J. and Syrjanen, J. and Shir, D. and Algeciras-Schimnich, A. and Lucas, J. and Martens, Y. A. and Carrasquillo, M. M. and others}, title = {{Association of Plasma Biomarkers of Alzheimer Disease With Cognition and Medical Comorbidities in a Biracial Cohort}}, journal = {Neurology}, year = {2023}, doi = {10.1212/wnl.0000000000207675}, pmid = {37580163}, url = {https://doi.org/10.1212/wnl.0000000000207675} } @article{grothe2021-34266917, author = {Grothe, M. J. and Moscoso, A. and Ashton, N. J. and Karikari, T. K. and Lantero-Rodriguez, J. and Snellman, A. and Zetterberg, H. and Blennow, K. and others}, title = {{Associations of Fully Automated CSF and Novel Plasma Biomarkers With Alzheimer Disease Neuropathology at Autopsy}}, journal = {Neurology}, year = {2021}, doi = {10.1212/wnl.0000000000012513}, pmid = {34266917}, url = {https://doi.org/10.1212/wnl.0000000000012513} } @article{boerwinkle2023-36517172, author = {Boerwinkle, A. H. and Gordon, B. A. and Wisch, J. and Flores, S. and Henson, R. L. and Butt, O. H. and McKay, N. and Chen, C. D. and others}, title = {{Comparison of amyloid burden in individuals with Down syndrome versus autosomal dominant Alzheimer's disease: a cross-sectional study}}, journal = {The Lancet. Neurology}, year = {2023}, doi = {10.1016/s1474-4422(22)00408-2}, pmid = {36517172}, url = {https://doi.org/10.1016/s1474-4422(22)00408-2} } @article{honig2023-37079306, author = {Honig, L. S. and Kang, M. S. and Lee, A. J. and Reyes-Dumeyer, D. and Piriz, A. and Soriano, B. and Franco, Y. and Coronado, Z. D. and others}, title = {{Evaluation of Plasma Biomarkers for A/T/N Classification of Alzheimer Disease Among Adults of Caribbean Hispanic Ethnicity}}, journal = {JAMA network open}, year = {2023}, doi = {10.1001/jamanetworkopen.2023.8214}, pmid = {37079306}, url = {https://doi.org/10.1001/jamanetworkopen.2023.8214} } @article{cousins2024-38306599, author = {Cousins, K. A. Q. and Irwin, D. J. and Tropea, T. F. and Rhodes, E. and Phillips, J. and Chen-Plotkin, A. S. and Brumm, M. C. and Coffey, C. S. and others}, title = {{Evaluation of ATNPD Framework and Biofluid Markers to Predict Cognitive Decline in Early Parkinson Disease}}, journal = {Neurology}, year = {2024}, doi = {10.1212/wnl.0000000000208033}, pmid = {38306599}, url = {https://doi.org/10.1212/wnl.0000000000208033} } @article{hazan2024-39353147, author = {Hazan, J. and Liu, K. Y. and Costello, H. and Isaacs, J. D. and Thambisetty, M. and Howard, R.}, title = {{Challenges in a Biological Definition of Alzheimer Disease}}, journal = {Neurology}, year = {2024}, doi = {10.1212/wnl.0000000000209884}, pmid = {39353147}, url = {https://doi.org/10.1212/wnl.0000000000209884} } @article{gomar2024-38922609, author = {Gomar, J. J. and Koppel, J.}, title = {{Psychosis in Alzheimer Disease and Elevations in Disease-Relevant Biomarkers}}, journal = {JAMA psychiatry}, year = {2024}, doi = {10.1001/jamapsychiatry.2024.1389}, pmid = {38922609}, url = {https://doi.org/10.1001/jamapsychiatry.2024.1389} } @article{li2023-38019518, author = {Li, X. and Yucel, R. and Clervius, H. and Kamalakar, K. and Zetterberg, H. and Blennow, K. and Zhang, J. and Adimora, A. and others}, title = {{Plasma Biomarkers of Alzheimer Disease in Women With and Without HIV}}, journal = {JAMA network open}, year = {2023}, doi = {10.1001/jamanetworkopen.2023.44194}, pmid = {38019518}, url = {https://doi.org/10.1001/jamanetworkopen.2023.44194} } @article{shrestha2025-40373252, author = {Shrestha, S. and Zhu, X. and Griswold, M. E. and Palta, P. and Sullivan, K. J. and Chen, H. and Schneider, A. L. C. and Moghekar, A. and others}, title = {{Olfaction and Plasma Biomarkers of Alzheimer Disease and Neurodegeneration in the Atherosclerosis Risk in Communities Study}}, journal = {Neurology}, year = {2025}, doi = {10.1212/wnl.0000000000213706}, pmid = {40373252}, url = {https://doi.org/10.1212/wnl.0000000000213706} } @article{liang2025-39836940, author = {Liang, Jingjing and Hussainy, Sadiya and Lee, Sara Michelle and Wu, Gray and Bautista, Natalie and Ding, Mao and Wang, Heming and LAFLEUR, BONNIE J. and others}, title = {{Association of Polygenic Risk Score for 5 Diseases With Alzheimer Disease Progression, Biomarkers, and Amyloid Deposition}}, journal = {Neurology}, year = {2025}, doi = {10.1212/wnl.0000000000210250}, pmid = {39836940}, url = {https://doi.org/10.1212/wnl.0000000000210250} } @article{nakamura2018-29420472, author = {Nakamura, Akinori and Kaneko, Naoki and Villemagne, Victor L. and Kato, Takashi and Doecke, James D. and Doré, Vincent and Fowler, Christopher James and Li, Qiao‐Xin and Martins, Ralph Nigel and Rowe, Christopher Cleon and Tomita, Taisuke and Matsuzaki, Katsumi and Ishii, Kenji and Ishii, Kazunari and Arahata, Yutaka and Iwamoto, Shinichi and Ito, Kengo and Tanaka, Koichi and Masters, Colin Louis and Yanagisawa, Katsuhiko}, title = {{High performance plasma amyloid-β biomarkers for Alzheimer’s disease}}, journal = {Nature}, year = {2018}, doi = {10.1038/nature25456}, pmid = {29420472}, url = {https://doi.org/10.1038/nature25456} } @article{hansson2021-34083813, author = {Hansson, Oskar}, title = {{Biomarkers for neurodegenerative diseases}}, journal = {Nature Medicine}, year = {2021}, doi = {10.1038/s41591-021-01382-x}, pmid = {34083813}, url = {https://doi.org/10.1038/s41591-021-01382-x} } @article{hansson2022-35908251, author = {Hansson, Oskar and Edelmayer, Rebecca M. and Boxer, Adam L. and Carrillo, María C. and Mielke, Michelle M. and Rabinovici, Gil D. and Salloway, Stephen and Sperling, Reisa Anne and Zetterberg, Henrik and Teunissen, Charlotte Elisabeth}, title = {{The Alzheimer's Association appropriate use recommendations for blood biomarkers in Alzheimer's disease}}, journal = {Alzheimer s \& Dementia}, year = {2022}, doi = {10.1002/alz.12756}, pmid = {35908251}, url = {https://doi.org/10.1002/alz.12756} } @article{chatterjee2023-36574591, author = {Chatterjee, P. and Pedrini, S. and Doecke, J. D. and Thota, R. and Villemagne, V. L. and Doré, V. and Singh, A. K. and Wang, P. and others}, title = {{Plasma Aβ42/40 ratio, p-tau181, GFAP, and NfL across the Alzheimer's disease continuum: A cross-sectional and longitudinal study in the AIBL cohort}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2023}, doi = {10.1002/alz.12724}, pmid = {36574591}, url = {https://doi.org/10.1002/alz.12724} } @article{ashton2023-36370462, author = {Ashton, N. J. and Puig-Pijoan, A. and Milà-Alomà, M. and Fernández-Lebrero, A. and García-Escobar, G. and González-Ortiz, F. and Kac, P. R. and Brum, W. S. and others}, title = {{Plasma and CSF biomarkers in a memory clinic: Head-to-head comparison of phosphorylated tau immunoassays}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2023}, doi = {10.1002/alz.12841}, pmid = {36370462}, url = {https://doi.org/10.1002/alz.12841} } @article{potter2021-33778150, author = {Potter, H. and Woodcock, J. H. and Boyd, T. D. and Coughlan, C. M. and O'Shaughnessy, JR. and Borges, M. T. and Thaker, A. A. and Raj, B. A. and others}, title = {{Safety and efficacy of sargramostim (GM-CSF) in the treatment of Alzheimer's disease}}, journal = {Alzheimer's \& dementia (New York, N. Y.)}, year = {2021}, doi = {10.1002/trc2.12158}, pmid = {33778150}, url = {https://doi.org/10.1002/trc2.12158} } @article{meng2019-31651358, author = {Meng, X. and Li, T. and Wang, X. and Lv, X. and Sun, Z. and Zhang, J. and Su, F. and Kang, S. and others}, title = {{Association between increased levels of amyloid-β oligomers in plasma and episodic memory loss in Alzheimer's disease}}, journal = {Alzheimer's research \& therapy}, year = {2019}, doi = {10.1186/s13195-019-0535-7}, pmid = {31651358}, url = {https://doi.org/10.1186/s13195-019-0535-7} } @article{strydom2018-29631614, author = {Strydom, A. and Heslegrave, A. and Startin, C. M. and Mok, K. Y. and Hardy, J. and Groet, J. and Nizetic, D. and Zetterberg, H. and others}, title = {{Neurofilament light as a blood biomarker for neurodegeneration in Down syndrome}}, journal = {Alzheimer's research \& therapy}, year = {2018}, doi = {10.1186/s13195-018-0367-x}, pmid = {29631614}, url = {https://doi.org/10.1186/s13195-018-0367-x} } @article{huber2024-38284555, author = {Huber, H. and Blennow, K. and Zetterberg, H. and Boada, M. and Jeromin, A. and Weninger, H. and Nuñez-Llaves, R. and Aguilera, N. and others}, title = {{Biomarkers of Alzheimer's disease and neurodegeneration in dried blood spots-A new collection method for remote settings}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2024}, doi = {10.1002/alz.13697}, pmid = {38284555}, url = {https://doi.org/10.1002/alz.13697} } @article{faura2020-31958084, author = {Faura, J. and Bustamante, A. and Penalba, A. and Giralt, D. and Simats, A. and Martínez-Sáez, E. and Alcolea, D. and Fortea, J. and others}, title = {{CCL23: A Chemokine Associated with Progression from Mild Cognitive Impairment to Alzheimer's Disease}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2020}, doi = {10.3233/jad-190753}, pmid = {31958084}, url = {https://doi.org/10.3233/jad-190753} } @article{sanchez2024-38105605, author = {Sanchez, E. and Wilkinson, T. and Coughlan, G. and Mirza, S. and Baril, A. A. and Ramirez, J. and Binns, M. A. and Black, S. E. and others}, title = {{Association of plasma biomarkers with cognition, cognitive decline, and daily function across and within neurodegenerative diseases: Results from the Ontario Neurodegenerative Disease Research Initiative}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2024}, doi = {10.1002/alz.13560}, pmid = {38105605}, url = {https://doi.org/10.1002/alz.13560} } @article{chiang2015-26228889, author = {Chiang, G. C. and Cruz Hernandez, J. C. and Kantarci, K. and Jack, C. R. and Weiner, M. W. and {Alzheimer's Disease Neuroimaging Initiative}}, title = {{Cerebral Microbleeds, CSF p-Tau, and Cognitive Decline: Significance of Anatomic Distribution}}, journal = {AJNR. American journal of neuroradiology}, year = {2015}, doi = {10.3174/ajnr.a4351}, pmid = {26228889}, url = {https://doi.org/10.3174/ajnr.a4351} } @article{rissman2024-39044490, author = {Rissman, R. A. and Donohue, M. C. and Langford, O. and Raman, R. and Abdel-Latif, S. and Yaari, R. and Holdridge, K. C. and Sims, JR. and others}, title = {{Longitudinal Phospho-tau217 Predicts Amyloid Positron Emission Tomography in Asymptomatic Alzheimer's Disease}}, journal = {The journal of prevention of Alzheimer's disease}, year = {2024}, doi = {10.14283/jpad.2024.134}, pmid = {39044490}, url = {https://doi.org/10.14283/jpad.2024.134} } @article{montoliugaya2023-38159140, author = {Montoliu-Gaya, L. and Alosco, M. L. and Yhang, E. and Tripodis, Y. and Sconzo, D. and Ally, M. and Grötschel, L. and Ashton, N. J. and others}, title = {{Optimal blood tau species for the detection of Alzheimer's disease neuropathology: an immunoprecipitation mass spectrometry and autopsy study}}, journal = {Acta neuropathologica}, year = {2023}, doi = {10.1007/s00401-023-02660-3}, pmid = {38159140}, url = {https://doi.org/10.1007/s00401-023-02660-3} } @article{janelidze2025-40289884, author = {Janelidze, S. and Ashton, N. J. and Orduña Dolado, A. and Nordström, U. and Bali, D. and Forsberg, K. M. E. and Keskin, I. and Mastrangelo, A. and others}, title = {{A comparison of p-tau assays for the specificity to detect tau changes in Alzheimer's disease}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2025}, doi = {10.1002/alz.70208}, pmid = {40289884}, url = {https://doi.org/10.1002/alz.70208} } @article{brum2024-38486040, author = {Brum, W. S. and Cullen, N. C. and Therriault, J. and Janelidze, S. and Rahmouni, N. and Stevenson, J. and Servaes, S. and Benedet, A. L. and others}, title = {{A blood-based biomarker workflow for optimal tau-PET referral in memory clinic settings}}, journal = {Nature communications}, year = {2024}, doi = {10.1038/s41467-024-46603-2}, pmid = {38486040}, url = {https://doi.org/10.1038/s41467-024-46603-2} } @article{pagonabarraga2022-35752549, author = {Pagonabarraga, J. and Pérez-González, R. and Bejr-Kasem, H. and Marín-Lahoz, J. and Horta-Barba, A. and Martinez-Horta, S. and Aracil-Bolaños, I. and Sampedro, F. and others}, title = {{Dissociable contribution of plasma NfL and p-tau181 to cognitive impairment in Parkinson's disease}}, journal = {Parkinsonism \& related disorders}, year = {2022}, doi = {10.1016/j.parkreldis.2022.05.020}, pmid = {35752549}, url = {https://doi.org/10.1016/j.parkreldis.2022.05.020} } @article{zhang2024-38753951, author = {Zhang, Y. and Ferreira, P. C. L. and Jacobsen, E. and Bellaver, B. and Pascoal, T. A. and Snitz, B. E. and Chang, C. H. and Villemagne, V. L. and others}, title = {{Association of plasma biomarkers of Alzheimer's disease and related disorders with cognition and cognitive decline: The MYHAT population-based study}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2024}, doi = {10.1002/alz.13829}, pmid = {38753951}, url = {https://doi.org/10.1002/alz.13829} } @article{huber2026-41491101, author = {Huber, H. and Montoliu-Gaya, L. and Brum, W. S. and Vávra, J. and Yakoub, Y. and Weninger, H. and Braun-Wohlfahrt, L. S. and Simrén, J. and others}, title = {{A minimally invasive dried blood spot biomarker test for the detection of Alzheimer's disease pathology}}, journal = {Nature medicine}, year = {2026}, doi = {10.1038/s41591-025-04080-0}, pmid = {41491101}, url = {https://doi.org/10.1038/s41591-025-04080-0} } @article{rudolph2025-40613474, author = {Rudolph, M. D. and Sutphen, C. L. and Register, T. C. and Lockhart, S. N. and Rundle, M. M. and Hughes, T. M. and Bateman, JR. and Sai, K. K. S. and others}, title = {{Evaluation of plasma p-tau217 for detecting amyloid pathology in a heterogeneous community-based cohort}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2025}, doi = {10.1002/alz.70426}, pmid = {40613474}, url = {https://doi.org/10.1002/alz.70426} } @article{huang2024-38159651, author = {Huang, L. and Huang, Q. and Xie, F. and Guo, Q.}, title = {{Neuropsychiatric symptoms in Alzheimer's continuum and their association with plasma biomarkers}}, journal = {Journal of affective disorders}, year = {2024}, doi = {10.1016/j.jad.2023.12.062}, pmid = {38159651}, url = {https://doi.org/10.1016/j.jad.2023.12.062} } @article{pan2023-37165172, author = {Pan, F. and Huang, Y. and Cai, X. and Wang, Y. and Guan, Y. and Deng, J. and Yang, D. and Zhu, J. and others}, title = {{Integrated algorithm combining plasma biomarkers and cognitive assessments accurately predicts brain β-amyloid pathology}}, journal = {Communications medicine}, year = {2023}, doi = {10.1038/s43856-023-00295-9}, pmid = {37165172}, url = {https://doi.org/10.1038/s43856-023-00295-9} } @article{zarkali2025-40776573, author = {Zarkali, A. and Thomas, G. and Paterson, R. and Hannaway, N. and Dobreva, I. and Heslegrave, A. J. and Veleva, E. and Zetterberg, H. and others}, title = {{Impaired Glymphatic Clearance, Measured Using Diffusion Tensor Image Analysis Along the Perivascular Space (DTI-ALPS), is Linked to Poor Cognitive Outcomes in Parkinson's Disease}}, journal = {Movement disorders : official journal of the Movement Disorder Society}, year = {2025}, doi = {10.1002/mds.30325}, pmid = {40776573}, url = {https://doi.org/10.1002/mds.30325} } @article{xu2026-42716078, author = {Xu, Yuexuan and Gunasekaran, Tamil Iniyan and Gu, Yian and Reyes-Dumeyer, Dolly and Piriz, Angel and Sanchez, Danurys and Mejia, Diones Rivera and Medrano, Martin and others}, title = {{Plasma phosphorylated tau 217 concentrations, APOE genotype, and timing of cognitive impairment in individuals across diverse racial and ethnic groups: a pooled analysis of prospective cohort studies}}, journal = {The Lancet. Neurology}, year = {2026}, doi = {10.1016/S1474-4422(26)00313-3}, pmid = {42716078}, url = {https://doi.org/10.1016/S1474-4422(26)00313-3} } @article{hall2012-22925882, author = {Hall, S. and Öhrfelt, A. and Constantinescu, R. and Andreasson, U. and Surova, Y. and Bostrom, F. and Nilsson, C. and Håkan, W. and others}, title = {{Accuracy of a panel of 5 cerebrospinal fluid biomarkers in the differential diagnosis of patients with dementia and/or parkinsonian disorders}}, journal = {Archives of neurology}, year = {2012}, doi = {10.1001/archneurol.2012.1654}, pmid = {22925882}, url = {https://doi.org/10.1001/archneurol.2012.1654} } @article{farrell2021-33199430, author = {Farrell, M. E. and Jiang, S. and Schultz, A. P. and Properzi, M. J. and Price, J. C. and Becker, J. A. and Jacobs, H. I. L. and Hanseeuw, B. J. and others}, title = {{Defining the Lowest Threshold for Amyloid-PET to Predict Future Cognitive Decline and Amyloid Accumulation}}, journal = {Neurology}, year = {2021}, doi = {10.1212/wnl.0000000000011214}, pmid = {33199430}, url = {https://doi.org/10.1212/wnl.0000000000011214} } @article{delaby2020-32514050, author = {Delaby, C. and Alcolea, D. and Carmona-Iragui, M. and Illán-Gala, I. and Morenas-Rodríguez, E. and Barroeta, I. and Altuna, M. and Estellés, T. and others}, title = {{Differential levels of Neurofilament Light protein in cerebrospinal fluid in patients with a wide range of neurodegenerative disorders}}, journal = {Scientific reports}, year = {2020}, doi = {10.1038/s41598-020-66090-x}, pmid = {32514050}, url = {https://doi.org/10.1038/s41598-020-66090-x} } @article{qu2021-33517704, author = {Qu, Y. and Tan, C. C. and Shen, X. N. and Li, H. Q. and Cui, M. and Tan, L. and Dong, Q. and Yu, J. T. and others}, title = {{Association of Plasma Neurofilament Light With Small Vessel Disease Burden in Nondemented Elderly: A Longitudinal Study}}, journal = {Stroke}, year = {2021}, doi = {10.1161/strokeaha.120.030302}, pmid = {33517704}, url = {https://doi.org/10.1161/strokeaha.120.030302} } @article{sarto2023-36450604, author = {Sarto, J. and Ruiz-García, R. and Guillén, N. and Ó, Ramos-Campoy and Falgàs, N. and Esteller, D. and Contador, J. and Fernández, G. and others}, title = {{Diagnostic Performance and Clinical Applicability of Blood-Based Biomarkers in a Prospective Memory Clinic Cohort}}, journal = {Neurology}, year = {2023}, doi = {10.1212/wnl.0000000000201597}, pmid = {36450604}, url = {https://doi.org/10.1212/wnl.0000000000201597} } @article{vandevrede2025-39928343, author = {VandeVrede, L. and Cho, H. and Sanderson-Cimino, M. and Wekselman, F. and Cobigo, Y. and Gorno-Tempini, M. L. and Heuer, H. W. and Kramer, J. H. and others}, title = {{Detection of Alzheimer Neuropathology in Alzheimer and Non-Alzheimer Clinical Syndromes With Blood-Based Biomarkers}}, journal = {JAMA neurology}, year = {2025}, doi = {10.1001/jamaneurol.2024.5017}, pmid = {39928343}, url = {https://doi.org/10.1001/jamaneurol.2024.5017} } @article{frederiksen2019-30873924, author = {Frederiksen, K. S. and Gjerum, L. and Waldemar, G. and Hasselbalch, S. G.}, title = {{Physical Activity as a Moderator of Alzheimer Pathology: A Systematic Review of Observational Studies}}, journal = {Current Alzheimer research}, year = {2019}, doi = {10.2174/1567205016666190315095151}, pmid = {30873924}, url = {https://doi.org/10.2174/1567205016666190315095151} } @article{lehmann2025-40513421, author = {Lehmann, S. and Gabelle, A. and Duchiron, M. and Busto, G. and Morchikh, M. and Delaby, C. and Hirtz, C. and Mondesert, E. and others}, title = {{Comparative performance of plasma pTau181/Aβ42, pTau217/Aβ42 ratios, and individual measurements in detecting brain amyloidosis}}, journal = {EBioMedicine}, year = {2025}, doi = {10.1016/j.ebiom.2025.105805}, pmid = {40513421}, url = {https://doi.org/10.1016/j.ebiom.2025.105805} } @article{duggan2022-35985823, author = {Duggan, M. R. and Peng, Z. and An, Y. and Kitner Triolo, M. H. and Shafer, A. T. and Davatzikos, C. and Erus, G. and Karikkineth, A. and others}, title = {{Herpes Viruses in the Baltimore Longitudinal Study of Aging: Associations With Brain Volumes, Cognitive Performance, and Plasma Biomarkers}}, journal = {Neurology}, year = {2022}, doi = {10.1212/wnl.0000000000201036}, pmid = {35985823}, url = {https://doi.org/10.1212/wnl.0000000000201036} } @article{boerwinkle2021-33931538, author = {Boerwinkle, A. H. and Wisch, J. K. and Chen, C. D. and Gordon, B. A. and Butt, O. H. and Schindler, S. E. and Sutphen, C. and Flores, S. and others}, title = {{Temporal Correlation of CSF and Neuroimaging in the Amyloid-Tau-Neurodegeneration Model of Alzheimer Disease}}, journal = {Neurology}, year = {2021}, doi = {10.1212/wnl.0000000000012123}, pmid = {33931538}, url = {https://doi.org/10.1212/wnl.0000000000012123} } @article{grasset2024-38626384, author = {Grasset, L. and Bouteloup, V. and Cacciamani, F. and Pellegrin, I. and Planche, V. and Chêne, G. and Dufouil, C. and {MEMENTO study group}}, title = {{Associations Between Blood-Based Biomarkers and Cognitive and Functional Trajectories Among Participants of the MEMENTO Cohort}}, journal = {Neurology}, year = {2024}, doi = {10.1212/wnl.0000000000209307}, pmid = {38626384}, url = {https://doi.org/10.1212/wnl.0000000000209307} } @article{zhou2022-36162981, author = {Zhou, L. and Shi, H. and Cheng, R. and Ge, M. and Hu, F. and Hou, L. and Xia, X. and Liu, X. and others}, title = {{Potential association between frailty and pTau in community-dwelling older adults}}, journal = {BMC geriatrics}, year = {2022}, doi = {10.1186/s12877-022-03454-0}, pmid = {36162981}, url = {https://doi.org/10.1186/s12877-022-03454-0} } @article{oeckl2023-37052206, author = {Oeckl, P. and Bluma, M. and Bucci, M. and Halbgebauer, S. and Chiotis, K. and Sandebring-Matton, A. and Ashton, N. J. and Molfetta, G. D. and others}, title = {{Blood β-synuclein is related to amyloid PET positivity in memory clinic patients}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2023}, doi = {10.1002/alz.13046}, pmid = {37052206}, url = {https://doi.org/10.1002/alz.13046} } @article{dhana2025-40067299, author = {Dhana, A. and DeCarli, C. S. and Dhana, K. and Desai, P. and Ng, T. K. S. and Evans, D. A. and Rajan, K. B.}, title = {{Cardiovascular Health and Biomarkers of Neurodegenerative Disease in Older Adults}}, journal = {JAMA network open}, year = {2025}, doi = {10.1001/jamanetworkopen.2025.0527}, pmid = {40067299}, url = {https://doi.org/10.1001/jamanetworkopen.2025.0527} } @article{karikari2021-33252199, author = {Karikari, T. K. and Emeršič, A. and Vrillon, A. and Lantero-Rodriguez, J. and Ashton, N. J. and Kramberger, M. G. and Dumurgier, J. and Hourregue, C. and others}, title = {{Head-to-head comparison of clinical performance of CSF phospho-tau T181 and T217 biomarkers for Alzheimer's disease diagnosis}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2021}, doi = {10.1002/alz.12236}, pmid = {33252199}, url = {https://doi.org/10.1002/alz.12236} } @article{chong2021-33792168, author = {Chong, JR. and Ashton, N. J. and Karikari, T. K. and Tanaka, T. and Saridin, F. N. and Reilhac, A. and Robins, E. G. and Nai, Y. H. and others}, title = {{Plasma P-tau181 to Aβ42 ratio is associated with brain amyloid burden and hippocampal atrophy in an Asian cohort of Alzheimer's disease patients with concomitant cerebrovascular disease}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2021}, doi = {10.1002/alz.12332}, pmid = {33792168}, url = {https://doi.org/10.1002/alz.12332} } @article{therriault2024-38471397, author = {Therriault, J. and Ashton, N. J. and Pola, I. and Triana-Baltzer, G. and Brum, W. S. and Di Molfetta, G. and Arslan, B. and Rahmouni, N. and others}, title = {{Comparison of two plasma p-tau217 assays to detect and monitor Alzheimer's pathology}}, journal = {EBioMedicine}, year = {2024}, doi = {10.1016/j.ebiom.2024.105046}, pmid = {38471397}, url = {https://doi.org/10.1016/j.ebiom.2024.105046} } @article{cai2023-37875471, author = {Cai, H. and Pang, Y. and Fu, X. and Ren, Z. and Jia, L.}, title = {{Plasma biomarkers predict Alzheimer's disease before clinical onset in Chinese cohorts}}, journal = {Nature communications}, year = {2023}, doi = {10.1038/s41467-023-42596-6}, pmid = {37875471}, url = {https://doi.org/10.1038/s41467-023-42596-6} } @article{feizpour2024-39437657, author = {Feizpour, A. and Doecke, J. D. and Doré, V. and Krishnadas, N. and Huang, K. and Bourgeat, P. and Laws, S. M. and Fowler, C. and others}, title = {{Detection and staging of Alzheimer's disease by plasma pTau217 on a high throughput immunoassay platform}}, journal = {EBioMedicine}, year = {2024}, doi = {10.1016/j.ebiom.2024.105405}, pmid = {39437657}, url = {https://doi.org/10.1016/j.ebiom.2024.105405} } @article{kac2022-35545792, author = {Kac, P. R. and Gonzalez-Ortiz, F. and Simrén, J. and Dewit, N. and Vanmechelen, E. and Zetterberg, H. and Blennow, K. and Ashton, N. J. and others}, title = {{Diagnostic value of serum versus plasma phospho-tau for Alzheimer's disease}}, journal = {Alzheimer's research \& therapy}, year = {2022}, doi = {10.1186/s13195-022-01011-w}, pmid = {35545792}, url = {https://doi.org/10.1186/s13195-022-01011-w} } @article{rauchmann2021-34187867, author = {Rauchmann, B. S. and Schneider-Axmann, T. and Perneczky, R.}, title = {{Associations of longitudinal plasma p-tau181 and NfL with tau-PET, Aβ-PET and cognition}}, journal = {Journal of neurology, neurosurgery, and psychiatry}, year = {2021}, doi = {10.1136/jnnp-2020-325537}, pmid = {34187867}, url = {https://doi.org/10.1136/jnnp-2020-325537} } @article{magdalinou2015-25589779, author = {Magdalinou, N. K. and Paterson, R. W. and Schott, J. M. and Fox, N. C. and Mummery, C. and Blennow, K. and Bhatia, K. and Morris, H. R. and others}, title = {{A panel of nine cerebrospinal fluid biomarkers may identify patients with atypical parkinsonian syndromes}}, journal = {Journal of neurology, neurosurgery, and psychiatry}, year = {2015}, doi = {10.1136/jnnp-2014-309562}, pmid = {25589779}, url = {https://doi.org/10.1136/jnnp-2014-309562} } @article{verde2021-34234641, author = {Verde, F. and Otto, M. and Silani, V.}, title = {{Neurofilament Light Chain as Biomarker for Amyotrophic Lateral Sclerosis and Frontotemporal Dementia}}, journal = {Frontiers in neuroscience}, year = {2021}, doi = {10.3389/fnins.2021.679199}, pmid = {34234641}, url = {https://doi.org/10.3389/fnins.2021.679199} } @article{fayed2008-18692749, author = {Fayed, N. and Dávila, J. and Oliveros, A. and Castillo, J. and Medrano, J. J.}, title = {{Utility of different MR modalities in mild cognitive impairment and its use as a predictor of conversion to probable dementia}}, journal = {Academic radiology}, year = {2008}, doi = {10.1016/j.acra.2008.04.008}, pmid = {18692749}, url = {https://doi.org/10.1016/j.acra.2008.04.008} } @article{cogswell2024-37963289, author = {Cogswell, P. M. and Lundt, E. S. and Therneau, T. M. and Wiste, H. J. and Graff-Radford, J. and Algeciras-Schimnich, A. and Lowe, V. J. and Mielke, M. M. and others}, title = {{Modeling the temporal evolution of plasma p-tau in relation to amyloid beta and tau PET}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2024}, doi = {10.1002/alz.13539}, pmid = {37963289}, url = {https://doi.org/10.1002/alz.13539} } @article{wojdala2024-39702308, author = {Wojdała, Anna L and Vanbrabant, Jeroen and Bayoumy, Sherif and Antwi-Berko, Daniel and Le Bastard, Nathalie and van der Flier, Wiesje M and Jeromin, Andreas and Lambrechts, Charlotte and others}, title = {{Analytical and clinical performance of eight Simoa® and Lumipulse® assays for automated measurement of plasma p-tau181 and p-tau217}}, journal = {Alzheimer's research \& therapy}, year = {2024}, doi = {10.1186/s13195-024-01630-5}, pmid = {39702308}, url = {https://doi.org/10.1186/s13195-024-01630-5} } @article{asken2024-39021585, author = {Asken, Breton M and DeSimone, Jesse C and Wang, Wei-En and McFarland, Karen N and Arias, Franchesca and Levy, Shellie-Anne and Fiala, Jacob and Velez-Uribe, Idaly and others}, title = {{Plasma p-tau217 concordance with amyloid PET among ethnically diverse older adults}}, journal = {Alzheimer's \& dementia (Amsterdam, Netherlands)}, year = {2024}, doi = {10.1002/dad2.12617}, pmid = {39021585}, url = {https://doi.org/10.1002/dad2.12617} }