% alzhub.org library filter % Source: https://alzhub.org/research?author=Vassar+R % 12 entries, in the order the page lists them. Built from alzhub.org's own records. % 0 entries have no readable author in the source record and carry no author field. @article{vassar2014-24646365, author = {Vassar, R. and Kuhn, P. H. and Haass, C. and Kennedy, M. E. and Rajendran, L. and Wong, P. C. and Lichtenthaler, S. F.}, title = {{Function, therapeutic potential and cell biology of BACE proteases: current status and future prospects}}, journal = {Journal of neurochemistry}, year = {2014}, doi = {10.1111/jnc.12715}, pmid = {24646365}, url = {https://doi.org/10.1111/jnc.12715} } @article{destrooper2010-20139999, author = {De Strooper, B. and Vassar, R. and Golde, T.}, title = {{The secretases: enzymes with therapeutic potential in Alzheimer disease}}, journal = {Nature reviews. Neurology}, year = {2010}, doi = {10.1038/nrneurol.2009.218}, pmid = {20139999}, url = {https://doi.org/10.1038/nrneurol.2009.218} } @article{mao2023-37429512, author = {Mao, C. and Xu, J. and Rasmussen, L. and Li, Y. and Adekkanattu, P. and Pacheco, J. and Bonakdarpour, B. and Vassar, R. and others}, title = {{AD-BERT: Using pre-trained language model to predict the progression from mild cognitive impairment to Alzheimer's disease}}, journal = {Journal of biomedical informatics}, year = {2023}, doi = {10.1016/j.jbi.2023.104442}, pmid = {37429512}, url = {https://doi.org/10.1016/j.jbi.2023.104442} } @article{cole2008-18650431, author = {Cole, S. L. and Vassar, R.}, title = {{The role of amyloid precursor protein processing by BACE1, the beta-secretase, in Alzheimer disease pathophysiology}}, journal = {The Journal of biological chemistry}, year = {2008}, doi = {10.1074/jbc.r800015200}, pmid = {18650431}, url = {https://doi.org/10.1074/jbc.r800015200} } @article{avrahami2013-23155049, author = {Avrahami, L. and Farfara, D. and Shaham-Kol, M. and Vassar, R. and Frenkel, D. and Eldar-Finkelman, H.}, title = {{Inhibition of glycogen synthase kinase-3 ameliorates β-amyloid pathology and restores lysosomal acidification and mammalian target of rapamycin activity in the Alzheimer disease mouse model: in vivo and in vitro studies}}, journal = {The Journal of biological chemistry}, year = {2013}, doi = {10.1074/jbc.m112.409250}, pmid = {23155049}, url = {https://doi.org/10.1074/jbc.m112.409250} } @article{vetrivel2009-19074428, author = {Vetrivel, K. S. and Meckler, X. and Chen, Y. and Nguyen, P. D. and Seidah, N. G. and Vassar, R. and Wong, P. C. and Fukata, M. and others}, title = {{Alzheimer disease Abeta production in the absence of S-palmitoylation-dependent targeting of BACE1 to lipid rafts}}, journal = {The Journal of biological chemistry}, year = {2009}, doi = {10.1074/jbc.m808920200}, pmid = {19074428}, url = {https://doi.org/10.1074/jbc.m808920200} } @article{hitt2012-22988240, author = {Hitt, B. and Riordan, S. M. and Kukreja, L. and Eimer, W. A. and Rajapaksha, T. W. and Vassar, R.}, title = {{β-Site amyloid precursor protein (APP)-cleaving enzyme 1 (BACE1)-deficient mice exhibit a close homolog of L1 (CHL1) loss-of-function phenotype involving axon guidance defects}}, journal = {The Journal of biological chemistry}, year = {2012}, doi = {10.1074/jbc.m112.415505}, pmid = {22988240}, url = {https://doi.org/10.1074/jbc.m112.415505} } @article{cole2005-15718241, author = {Cole, S. L. and Grudzien, A. and Manhart, I. O. and Kelly, B. L. and Oakley, H. and Vassar, R.}, title = {{Statins cause intracellular accumulation of amyloid precursor protein, beta-secretase-cleaved fragments, and amyloid beta-peptide via an isoprenoid-dependent mechanism}}, journal = {The Journal of biological chemistry}, year = {2005}, doi = {10.1074/jbc.m413895200}, pmid = {15718241}, url = {https://doi.org/10.1074/jbc.m413895200} } @article{sasaguri2017-28768718, author = {Sasaguri, H. and Nilsson, P. and Hashimoto, S. and Nagata, K. and Saito, T. and De Strooper, B. and Hardy, J. and Vassar, R. and others}, title = {{APP mouse models for Alzheimer's disease preclinical studies}}, journal = {The EMBO journal}, year = {2017}, doi = {10.15252/embj.201797397}, pmid = {28768718}, url = {https://doi.org/10.15252/embj.201797397} } @article{hampel2021-32223911, author = {Hampel, H. and Vassar, R. and De Strooper, B. and Hardy, J. and Willem, M. and Singh, N. and Zhou, J. and Yan, R. and others}, title = {{The β-Secretase BACE1 in Alzheimer's Disease}}, journal = {Biological psychiatry}, year = {2021}, doi = {10.1016/j.biopsych.2020.02.001}, pmid = {32223911}, url = {https://doi.org/10.1016/j.biopsych.2020.02.001} } @article{kelly2005-16002400, author = {Kelly, B. L. and Vassar, R. and Ferreira, A.}, title = {{Beta-amyloid-induced dynamin 1 depletion in hippocampal neurons. A potential mechanism for early cognitive decline in Alzheimer disease}}, journal = {The Journal of biological chemistry}, year = {2005}, doi = {10.1074/jbc.m503259200}, pmid = {16002400}, url = {https://doi.org/10.1074/jbc.m503259200} } @article{perez2012-23071869, author = {Perez, S. E. and Nadeem, M. and Sadleir, K. R. and Matras, J. and Kelley, C. M. and Counts, S. E. and Vassar, R. and Mufson, E. J.}, title = {{Dimebon alters hippocampal amyloid pathology in 3xTg-AD mice}}, journal = {International journal of physiology, pathophysiology and pharmacology}, year = {2012}, pmid = {23071869} }