% alzhub.org library filter % Source: https://alzhub.org/research?author=Selkoe+DJ % 41 entries, in the order the page lists them. Built from alzhub.org's own records. % 0 entries have no readable author in the source record and carry no author field. @article{mengel2020-32192521, author = {Mengel, D. and Liu, W. and Glynn, R. J. and Selkoe, D. J. and Strydom, A. and Lai, F. and Rosas, H. D. and Torres, A. and others}, title = {{Dynamics of plasma biomarkers in Down syndrome: the relative levels of Aβ42 decrease with age, whereas NT1 tau and NfL increase}}, journal = {Alzheimer's research \& therapy}, year = {2020}, doi = {10.1186/s13195-020-00593-7}, pmid = {32192521}, url = {https://doi.org/10.1186/s13195-020-00593-7} } @article{rabinovici2025-40155270, author = {Rabinovici, G. D. and Selkoe, D. J. and Schindler, S. E. and Aisen, P. and Apostolova, L. G. and Atri, A. and Greenberg, S. M. and Hendrix, S. B. and others}, title = {{Donanemab: Appropriate use recommendations}}, journal = {The journal of prevention of Alzheimer's disease}, year = {2025}, doi = {10.1016/j.tjpad.2025.100150}, pmid = {40155270}, url = {https://doi.org/10.1016/j.tjpad.2025.100150} } @article{mcdonald2010-20403962, author = {Mc Donald, J. M. and Savva, G. M. and Brayne, C. and Welzel, A. T. and Forster, G. and Shankar, G. M. and Selkoe, D. J. and Ince, P. G. and others}, title = {{The presence of sodium dodecyl sulphate-stable Abeta dimers is strongly associated with Alzheimer-type dementia}}, journal = {Brain : a journal of neurology}, year = {2010}, doi = {10.1093/brain/awq065}, pmid = {20403962}, url = {https://doi.org/10.1093/brain/awq065} } @article{yang2017-28053038, author = {Yang, T. and Li, S. and Xu, H. and Walsh, D. M. and Selkoe, D. J.}, title = {{Large Soluble Oligomers of Amyloid β-Protein from Alzheimer Brain Are Far Less Neuroactive Than the Smaller Oligomers to Which They Dissociate}}, journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience}, year = {2017}, doi = {10.1523/jneurosci.1698-16.2016}, pmid = {28053038}, url = {https://doi.org/10.1523/jneurosci.1698-16.2016} } @article{leissring2003-14687544, author = {Leissring, M. A. and Farris, W. and Chang, A. Y. and Walsh, D. M. and Wu, X. and Sun, X. and Frosch, M. P. and Selkoe, D. J.}, title = {{Enhanced proteolysis of beta-amyloid in APP transgenic mice prevents plaque formation, secondary pathology, and premature death}}, journal = {Neuron}, year = {2003}, doi = {10.1016/s0896-6273(03)00787-6}, pmid = {14687544}, url = {https://doi.org/10.1016/s0896-6273(03)00787-6} } @article{hemming2005-16154999, author = {Hemming, M. L. and Selkoe, D. J.}, title = {{Amyloid beta-protein is degraded by cellular angiotensin-converting enzyme (ACE) and elevated by an ACE inhibitor}}, journal = {The Journal of biological chemistry}, year = {2005}, doi = {10.1074/jbc.m508460200}, pmid = {16154999}, url = {https://doi.org/10.1074/jbc.m508460200} } @article{selkoe1988-3140239, author = {Selkoe, D. J. and Podlisny, M. B. and Joachim, C. L. and Vickers, E. A. and Lee, G. and Fritz, L. C. and Oltersdorf, T.}, title = {{Beta-amyloid precursor protein of Alzheimer disease occurs as 110- to 135-kilodalton membrane-associated proteins in neural and nonneural tissues}}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, year = {1988}, doi = {10.1073/pnas.85.19.7341}, pmid = {3140239}, url = {https://doi.org/10.1073/pnas.85.19.7341} } @article{hemming2008-18942891, author = {Hemming, M. L. and Elias, J. E. and Gygi, S. P. and Selkoe, D. J.}, title = {{Proteomic profiling of gamma-secretase substrates and mapping of substrate requirements}}, journal = {PLoS biology}, year = {2008}, doi = {10.1371/journal.pbio.0060257}, pmid = {18942891}, url = {https://doi.org/10.1371/journal.pbio.0060257} } @article{citron1996-8917563, author = {Citron, M. and Diehl, T. S. and Gordon, G. and Biere, A. L. and Seubert, P. and Selkoe, D. J.}, title = {{Evidence that the 42- and 40-amino acid forms of amyloid beta protein are generated from the beta-amyloid precursor protein by different protease activities}}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, year = {1996}, doi = {10.1073/pnas.93.23.13170}, pmid = {8917563}, url = {https://doi.org/10.1073/pnas.93.23.13170} } @article{xia1997-9223340, author = {Xia, W. and Zhang, J. and Perez, R. and Koo, E. H. and Selkoe, D. J.}, title = {{Interaction between amyloid precursor protein and presenilins in mammalian cells: implications for the pathogenesis of Alzheimer disease}}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, year = {1997}, doi = {10.1073/pnas.94.15.8208}, pmid = {9223340}, url = {https://doi.org/10.1073/pnas.94.15.8208} } @article{hemming2007-17760499, author = {Hemming, M. L. and Patterson, M. and Reske-Nielsen, C. and Lin, L. and Isacson, O. and Selkoe, D. J.}, title = {{Reducing amyloid plaque burden via ex vivo gene delivery of an Abeta-degrading protease: a novel therapeutic approach to Alzheimer disease}}, journal = {PLoS medicine}, year = {2007}, doi = {10.1371/journal.pmed.0040262}, pmid = {17760499}, url = {https://doi.org/10.1371/journal.pmed.0040262} } @article{hung1992-1409654, author = {Hung, A. Y. and Koo, E. H. and Haass, C. and Selkoe, D. J.}, title = {{Increased expression of beta-amyloid precursor protein during neuronal differentiation is not accompanied by secretory cleavage}}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, year = {1992}, doi = {10.1073/pnas.89.20.9439}, pmid = {1409654}, url = {https://doi.org/10.1073/pnas.89.20.9439} } @article{greenberg1994-8041753, author = {Greenberg, S. M. and Koo, E. H. and Selkoe, D. J. and Qiu, W. Q. and Kosik, K. S.}, title = {{Secreted beta-amyloid precursor protein stimulates mitogen-activated protein kinase and enhances tau phosphorylation}}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, year = {1994}, doi = {10.1073/pnas.91.15.7104}, pmid = {8041753}, url = {https://doi.org/10.1073/pnas.91.15.7104} } @article{joachim1992-1605946, author = {Joachim, C. L. and Selkoe, D. J.}, title = {{The seminal role of beta-amyloid in the pathogenesis of Alzheimer disease}}, journal = {Alzheimer disease and associated disorders}, year = {1992}, doi = {10.1097/00002093-199205000-00003}, pmid = {1605946}, url = {https://doi.org/10.1097/00002093-199205000-00003} } @article{selkoe1999-10392577, author = {Selkoe, D. J.}, title = {{Translating cell biology into therapeutic advances in Alzheimer's disease}}, journal = {Nature}, year = {1999}, doi = {10.1038/399a023}, pmid = {10392577}, url = {https://doi.org/10.1038/399a023} } @article{liu2019-30626721, author = {Liu, L. and Ding, L. and Rovere, M. and Wolfe, M. S. and Selkoe, D. J.}, title = {{A cellular complex of BACE1 and γ-secretase sequentially generates Aβ from its full-length precursor}}, journal = {The Journal of cell biology}, year = {2019}, doi = {10.1083/jcb.201806205}, pmid = {30626721}, url = {https://doi.org/10.1083/jcb.201806205} } @article{haass1992-1608449, author = {Haass, C. and Koo, E. H. and Mellon, A. and Hung, A. Y. and Selkoe, D. J.}, title = {{Targeting of cell-surface beta-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments}}, journal = {Nature}, year = {1992}, doi = {10.1038/357500a0}, pmid = {1608449}, url = {https://doi.org/10.1038/357500a0} } @article{joachim1989-2528696, author = {Joachim, C. L. and Mori, H. and Selkoe, D. J.}, title = {{Amyloid beta-protein deposition in tissues other than brain in Alzheimer's disease}}, journal = {Nature}, year = {1989}, doi = {10.1038/341226a0}, pmid = {2528696}, url = {https://doi.org/10.1038/341226a0} } @article{townsend2006-17192927, author = {Townsend, M. and Cleary, J. P. and Mehta, T. and Hofmeister, J. and Lesne, S. and O'Hare, E. and Walsh, D. M. and Selkoe, D. J.}, title = {{Orally available compound prevents deficits in memory caused by the Alzheimer amyloid-beta oligomers}}, journal = {Annals of neurology}, year = {2006}, doi = {10.1002/ana.21051}, pmid = {17192927}, url = {https://doi.org/10.1002/ana.21051} } @article{joachim1988-3415200, author = {Joachim, C. L. and Morris, J. H. and Selkoe, D. J.}, title = {{Clinically diagnosed Alzheimer's disease: autopsy results in 150 cases}}, journal = {Annals of neurology}, year = {1988}, doi = {10.1002/ana.410240110}, pmid = {3415200}, url = {https://doi.org/10.1002/ana.410240110} } @article{yamazaki1995-7721945, author = {Yamazaki, T. and Selkoe, D. J. and Koo, E. H.}, title = {{Trafficking of cell surface beta-amyloid precursor protein: retrograde and transcytotic transport in cultured neurons}}, journal = {The Journal of cell biology}, year = {1995}, doi = {10.1083/jcb.129.2.431}, pmid = {7721945}, url = {https://doi.org/10.1083/jcb.129.2.431} } @article{li2020-32180217, author = {Li, S. and Selkoe, D. J.}, title = {{A mechanistic hypothesis for the impairment of synaptic plasticity by soluble Aβ oligomers from Alzheimer's brain}}, journal = {Journal of neurochemistry}, year = {2020}, doi = {10.1111/jnc.15007}, pmid = {32180217}, url = {https://doi.org/10.1111/jnc.15007} } @article{aisen2020-32463066, author = {Aisen, P. S. and Cummings, J. and Doody, R. and Kramer, L. and Salloway, S. and Selkoe, D. J. and Sims, J. and Sperling, R. A. and others}, title = {{The Future of Anti-Amyloid Trials}}, journal = {The journal of prevention of Alzheimer's disease}, year = {2020}, doi = {10.14283/jpad.2020.24}, pmid = {32463066}, url = {https://doi.org/10.14283/jpad.2020.24} } @article{stephenson1996-9173912, author = {Stephenson, D. T. and Lemere, C. A. and Selkoe, D. J. and Clemens, J. A.}, title = {{Cytosolic phospholipase A2 (cPLA2) immunoreactivity is elevated in Alzheimer's disease brain}}, journal = {Neurobiology of disease}, year = {1996}, doi = {10.1006/nbdi.1996.0005}, pmid = {9173912}, url = {https://doi.org/10.1006/nbdi.1996.0005} } @article{walsh2007-17286590, author = {Walsh, D. M. and Selkoe, D. J.}, title = {{A beta oligomers - a decade of discovery}}, journal = {Journal of neurochemistry}, year = {2007}, doi = {10.1111/j.1471-4159.2006.04426.x}, pmid = {17286590}, url = {https://doi.org/10.1111/j.1471-4159.2006.04426.x} } @article{shen1997-9160754, author = {Shen, J. and Bronson, R. T. and Chen, D. F. and Xia, W. and Selkoe, D. J. and Tonegawa, S.}, title = {{Skeletal and CNS defects in Presenilin-1-deficient mice}}, journal = {Cell}, year = {1997}, doi = {10.1016/s0092-8674(00)80244-5}, pmid = {9160754}, url = {https://doi.org/10.1016/s0092-8674(00)80244-5} } @article{selkoe1998-9854312, author = {Selkoe, D. J.}, title = {{The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease}}, journal = {Trends in cell biology}, year = {1998}, doi = {10.1016/s0962-8924(98)01363-4}, pmid = {9854312}, url = {https://doi.org/10.1016/s0962-8924(98)01363-4} } @article{selkoe2004-15516999, author = {Selkoe, D. J.}, title = {{Cell biology of protein misfolding: the examples of Alzheimer's and Parkinson's diseases}}, journal = {Nature cell biology}, year = {2004}, doi = {10.1038/ncb1104-1054}, pmid = {15516999}, url = {https://doi.org/10.1038/ncb1104-1054} } @article{kimberly2003-12740439, author = {Kimberly, W. T. and LaVoie, M. J. and Ostaszewski, B. L. and Ye, W. and Wolfe, M. S. and Selkoe, D. J.}, title = {{Gamma-secretase is a membrane protein complex comprised of presenilin, nicastrin, Aph-1, and Pen-2}}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, year = {2003}, doi = {10.1073/pnas.1037392100}, pmid = {12740439}, url = {https://doi.org/10.1073/pnas.1037392100} } @article{abraham1988-3257719, author = {Abraham, C. R. and Selkoe, D. J. and Potter, H.}, title = {{Immunochemical identification of the serine protease inhibitor alpha 1-antichymotrypsin in the brain amyloid deposits of Alzheimer's disease}}, journal = {Cell}, year = {1988}, doi = {10.1016/0092-8674(88)90462-x}, pmid = {3257719}, url = {https://doi.org/10.1016/0092-8674(88)90462-x} } @article{masters2012-22675658, author = {Masters, C. L. and Selkoe, D. J.}, title = {{Biochemistry of amyloid β-protein and amyloid deposits in Alzheimer disease}}, journal = {Cold Spring Harbor perspectives in medicine}, year = {2012}, doi = {10.1101/cshperspect.a006262}, pmid = {22675658}, url = {https://doi.org/10.1101/cshperspect.a006262} } @article{shepardson2011-21987540, author = {Shepardson, N. E. and Shankar, G. M. and Selkoe, D. J.}, title = {{Cholesterol level and statin use in Alzheimer disease: I. Review of epidemiological and preclinical studies}}, journal = {Archives of neurology}, year = {2011}, doi = {10.1001/archneurol.2011.203}, pmid = {21987540}, url = {https://doi.org/10.1001/archneurol.2011.203} } @article{selkoe2008-18359102, author = {Selkoe, D. J.}, title = {{Soluble oligomers of the amyloid beta-protein impair synaptic plasticity and behavior}}, journal = {Behavioural brain research}, year = {2008}, doi = {10.1016/j.bbr.2008.02.016}, pmid = {18359102}, url = {https://doi.org/10.1016/j.bbr.2008.02.016} } @article{shankar2007-17360908, author = {Shankar, G. M. and Bloodgood, B. L. and Townsend, M. and Walsh, D. M. and Selkoe, D. J. and Sabatini, B. L.}, title = {{Natural oligomers of the Alzheimer amyloid-beta protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway}}, journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience}, year = {2007}, doi = {10.1523/jneurosci.4970-06.2007}, pmid = {17360908}, url = {https://doi.org/10.1523/jneurosci.4970-06.2007} } @article{walsh2004-15450169, author = {Walsh, D. M. and Selkoe, D. J.}, title = {{Deciphering the molecular basis of memory failure in Alzheimer's disease}}, journal = {Neuron}, year = {2004}, doi = {10.1016/j.neuron.2004.09.010}, pmid = {15450169}, url = {https://doi.org/10.1016/j.neuron.2004.09.010} } @article{li2011-21543591, author = {Li, S. and Jin, M. and Koeglsperger, T. and Shepardson, N. E. and Shankar, G. M. and Selkoe, D. J.}, title = {{Soluble Aβ oligomers inhibit long-term potentiation through a mechanism involving excessive activation of extrasynaptic NR2B-containing NMDA receptors}}, journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience}, year = {2011}, doi = {10.1523/jneurosci.0203-11.2011}, pmid = {21543591}, url = {https://doi.org/10.1523/jneurosci.0203-11.2011} } @article{townsend2006-16469784, author = {Townsend, M. and Shankar, G. M. and Mehta, T. and Walsh, D. M. and Selkoe, D. J.}, title = {{Effects of secreted oligomers of amyloid beta-protein on hippocampal synaptic plasticity: a potent role for trimers}}, journal = {The Journal of physiology}, year = {2006}, doi = {10.1113/jphysiol.2005.103754}, pmid = {16469784}, url = {https://doi.org/10.1113/jphysiol.2005.103754} } @article{haass1991-1744690, author = {Haass, C. and Hung, A. Y. and Selkoe, D. J.}, title = {{Processing of beta-amyloid precursor protein in microglia and astrocytes favors an internal localization over constitutive secretion}}, journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience}, year = {1991}, doi = {10.1523/jneurosci.11-12-03783.1991}, pmid = {1744690}, url = {https://doi.org/10.1523/jneurosci.11-12-03783.1991} } @article{mori2002-12440481, author = {Mori, C. and Spooner, E. T. and Wisniewsk, K. E. and Wisniewski, T. M. and Yamaguch, H. and Saido, T. C. and Tolan, D. R. and Selkoe, D. J. and others}, title = {{Intraneuronal Abeta42 accumulation in Down syndrome brain}}, journal = {Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis}, year = {2002}, doi = {10.3109/13506120208995241}, pmid = {12440481}, url = {https://doi.org/10.3109/13506120208995241} } @article{monsonego2001-11517335, author = {Monsonego, A. and Maron, R. and Zota, V. and Selkoe, D. J. and Weiner, H. L.}, title = {{Immune hyporesponsiveness to amyloid beta-peptide in amyloid precursor protein transgenic mice: implications for the pathogenesis and treatment of Alzheimer's disease}}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, year = {2001}, doi = {10.1073/pnas.191118298}, pmid = {11517335}, url = {https://doi.org/10.1073/pnas.191118298} } @article{butler2025-35ab99e8, author = {Butler, P. M. and Francis, A. and Meunier, A. L. and Anderson, A. K. and Hennessey, E. L. and Miller, M. B. and Lemere, C. A. and Selkoe, D. J. and others}, title = {{Anti-amyloid antibody equilibrium binding to Aβ aggregates from human Alzheimer disease brain}}, journal = {bioRxiv}, year = {2025}, doi = {10.1101/2025.05.20.654902}, url = {https://doi.org/10.1101/2025.05.20.654902} }