% alzhub.org library filter % Source: https://alzhub.org/research?author=Holtzman+DM&institution=I4210123851 % 32 entries, in the order the page lists them. Built from alzhub.org's own records. % 0 entries have no readable author in the source record and carry no author field. @article{piccio2016-26754641, author = {Piccio, L. and Deming, Y. and Del-Águila, J. L. and Ghezzi, L. and Holtzman, D. M. and Fagan, A. M. and Fenoglio, C. and Galimberti, D. and others}, title = {{Cerebrospinal fluid soluble TREM2 is higher in Alzheimer disease and associated with mutation status}}, journal = {Acta neuropathologica}, year = {2016}, doi = {10.1007/s00401-016-1533-5}, pmid = {26754641}, url = {https://doi.org/10.1007/s00401-016-1533-5} } @article{ju2013-23479184, author = {Ju, Y. E. and McLeland, J. S. and Toedebusch, C. D. and Xiong, C. and Fagan, A. M. and Duntley, S. P. and Morris, J. C. and Holtzman, D. M.}, title = {{Sleep quality and preclinical Alzheimer disease}}, journal = {JAMA neurology}, year = {2013}, doi = {10.1001/jamaneurol.2013.2334}, pmid = {23479184}, url = {https://doi.org/10.1001/jamaneurol.2013.2334} } @article{self2023-37667136, author = {Self, W. K. and Holtzman, D. M.}, title = {{Emerging diagnostics and therapeutics for Alzheimer disease}}, journal = {Nature medicine}, year = {2023}, doi = {10.1038/s41591-023-02505-2}, pmid = {37667136}, url = {https://doi.org/10.1038/s41591-023-02505-2} } @article{vlassenko2016-27398953, author = {Vlassenko, A. G. and McCue, L. and Jasielec, M. S. and Su, Y. and Gordon, B. A. and Xiong, C. and Holtzman, D. M. and Benzinger, T. L. and others}, title = {{Imaging and cerebrospinal fluid biomarkers in early preclinical alzheimer disease}}, journal = {Annals of neurology}, year = {2016}, doi = {10.1002/ana.24719}, pmid = {27398953}, url = {https://doi.org/10.1002/ana.24719} } @article{gordon2016-27548756, author = {Gordon, B. A. and Blazey, T. and Su, Y. and Fagan, A. M. and Holtzman, D. M. and Morris, J. C. and Benzinger, T. L.}, title = {{Longitudinal β-Amyloid Deposition and Hippocampal Volume in Preclinical Alzheimer Disease and Suspected Non-Alzheimer Disease Pathophysiology}}, journal = {JAMA neurology}, year = {2016}, doi = {10.1001/jamaneurol.2016.2642}, pmid = {27548756}, url = {https://doi.org/10.1001/jamaneurol.2016.2642} } @article{bell2012-22622580, author = {Bell, R. D. and Winkler, E. A. and Singh, I. and Sagare, A. P. and Deane, R. and Wu, Z. and Holtzman, D. M. and Betsholtz, C. and others}, title = {{Apolipoprotein E controls cerebrovascular integrity via cyclophilin A}}, journal = {Nature}, year = {2012}, doi = {10.1038/nature11087}, pmid = {22622580}, url = {https://doi.org/10.1038/nature11087} } @article{brier2012-22745490, author = {Brier, M. R. and Thomas, J. B. and Snyder, A. Z. and Benzinger, T. L. and Zhang, D. and Raichle, M. E. and Holtzman, D. M. and Morris, J. C. and others}, title = {{Loss of intranetwork and internetwork resting state functional connections with Alzheimer's disease progression}}, journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience}, year = {2012}, doi = {10.1523/jneurosci.5698-11.2012}, pmid = {22745490}, url = {https://doi.org/10.1523/jneurosci.5698-11.2012} } @article{tarawneh2015-25867677, author = {Tarawneh, R. and Head, D. and Allison, S. and Buckles, V. and Fagan, A. M. and Ladenson, J. H. and Morris, J. C. and Holtzman, D. M.}, title = {{Cerebrospinal Fluid Markers of Neurodegeneration and Rates of Brain Atrophy in Early Alzheimer Disease}}, journal = {JAMA neurology}, year = {2015}, doi = {10.1001/jamaneurol.2015.0202}, pmid = {25867677}, url = {https://doi.org/10.1001/jamaneurol.2015.0202} } @article{martens2022-35298921, author = {Martens, Y. A. and Zhao, N. and Liu, C. C. and Kanekiyo, T. and Yang, A. J. and Goate, A. M. and Holtzman, D. M. and Bu, G.}, title = {{ApoE Cascade Hypothesis in the pathogenesis of Alzheimer's disease and related dementias}}, journal = {Neuron}, year = {2022}, doi = {10.1016/j.neuron.2022.03.004}, pmid = {35298921}, url = {https://doi.org/10.1016/j.neuron.2022.03.004} } @article{bateman2006-16799555, author = {Bateman, R. J. and Munsell, L. Y. and Morris, J. C. and Swarm, R. and Yarasheski, K. E. and Holtzman, D. M.}, title = {{Human amyloid-beta synthesis and clearance rates as measured in cerebrospinal fluid in vivo}}, journal = {Nature medicine}, year = {2006}, doi = {10.1038/nm1438}, pmid = {16799555}, url = {https://doi.org/10.1038/nm1438} } @article{babulal2016-27426238, author = {Babulal, G. M. and Ghoshal, N. and Head, D. and Vernon, E. K. and Holtzman, D. M. and Benzinger, T. L. S. and Fagan, A. M. and Morris, J. C. and others}, title = {{Mood Changes in Cognitively Normal Older Adults are Linked to Alzheimer Disease Biomarker Levels}}, journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry}, year = {2016}, doi = {10.1016/j.jagp.2016.04.004}, pmid = {27426238}, url = {https://doi.org/10.1016/j.jagp.2016.04.004} } @article{perrin2009-19829371, author = {Perrin, R. J. and Fagan, A. M. and Holtzman, D. M.}, title = {{Multimodal techniques for diagnosis and prognosis of Alzheimer's disease}}, journal = {Nature}, year = {2009}, doi = {10.1038/nature08538}, pmid = {19829371}, url = {https://doi.org/10.1038/nature08538} } @article{holtzman2011-21471435, author = {Holtzman, D. M. and Morris, J. C. and Goate, A. M.}, title = {{Alzheimer's disease: the challenge of the second century}}, journal = {Science translational medicine}, year = {2011}, doi = {10.1126/scitranslmed.3002369}, pmid = {21471435}, url = {https://doi.org/10.1126/scitranslmed.3002369} } @article{deane2008-19033669, author = {Deane, R. and Sagare, A. and Hamm, K. and Parisi, M. and Lane, S. and Finn, M. B. and Holtzman, D. M. and Zlokovic, B. V.}, title = {{apoE isoform-specific disruption of amyloid beta peptide clearance from mouse brain}}, journal = {The Journal of clinical investigation}, year = {2008}, doi = {10.1172/jci36663}, pmid = {19033669}, url = {https://doi.org/10.1172/jci36663} } @article{jain2023-36219197, author = {Jain, N. and Lewis, C. A. and Ulrich, J. D. and Holtzman, D. M.}, title = {{Chronic TREM2 activation exacerbates Aβ-associated tau seeding and spreading}}, journal = {The Journal of experimental medicine}, year = {2023}, doi = {10.1084/jem.20220654}, pmid = {36219197}, url = {https://doi.org/10.1084/jem.20220654} } @article{shi2018-30140051, author = {Shi, Y. and Holtzman, D. M.}, title = {{Interplay between innate immunity and Alzheimer disease: APOE and TREM2 in the spotlight}}, journal = {Nature reviews. Immunology}, year = {2018}, doi = {10.1038/s41577-018-0051-1}, pmid = {30140051}, url = {https://doi.org/10.1038/s41577-018-0051-1} } @article{faraco2019-31645758, author = {Faraco, G. and Hochrainer, K. and Segarra, S. G. and Schaeffer, S. and Santisteban, M. M. and Menon, A. and Jiang, H. and Holtzman, D. M. and others}, title = {{Dietary salt promotes cognitive impairment through tau phosphorylation}}, journal = {Nature}, year = {2019}, doi = {10.1038/s41586-019-1688-z}, pmid = {31645758}, url = {https://doi.org/10.1038/s41586-019-1688-z} } @article{gratuze2018-30572908, author = {Gratuze, M. and Leyns, C. E. G. and Holtzman, D. M.}, title = {{New insights into the role of TREM2 in Alzheimer's disease}}, journal = {Molecular neurodegeneration}, year = {2018}, doi = {10.1186/s13024-018-0298-9}, pmid = {30572908}, url = {https://doi.org/10.1186/s13024-018-0298-9} } @article{ulrich2017-28426958, author = {Ulrich, J. D. and Ulland, T. K. and Colonna, M. and Holtzman, D. M.}, title = {{Elucidating the Role of TREM2 in Alzheimer's Disease}}, journal = {Neuron}, year = {2017}, doi = {10.1016/j.neuron.2017.02.042}, pmid = {28426958}, url = {https://doi.org/10.1016/j.neuron.2017.02.042} } @article{leyns2017-28662669, author = {Leyns, C. E. G. and Holtzman, D. M.}, title = {{Glial contributions to neurodegeneration in tauopathies}}, journal = {Molecular neurodegeneration}, year = {2017}, doi = {10.1186/s13024-017-0192-x}, pmid = {28662669}, url = {https://doi.org/10.1186/s13024-017-0192-x} } @article{chen2021-33176118, author = {Chen, Y. and Strickland, M. R. and Soranno, A. and Holtzman, D. M.}, title = {{Apolipoprotein E: Structural Insights and Links to Alzheimer Disease Pathogenesis}}, journal = {Neuron}, year = {2021}, doi = {10.1016/j.neuron.2020.10.008}, pmid = {33176118}, url = {https://doi.org/10.1016/j.neuron.2020.10.008} } @article{tarawneh2012-22357717, author = {Tarawneh, R. and Lee, J. M. and Ladenson, J. H. and Morris, J. C. and Holtzman, D. M.}, title = {{CSF VILIP-1 predicts rates of cognitive decline in early Alzheimer disease}}, journal = {Neurology}, year = {2012}, doi = {10.1212/wnl.0b013e318248e568}, pmid = {22357717}, url = {https://doi.org/10.1212/wnl.0b013e318248e568} } @article{mahan2022-35109920, author = {Mahan, T. E. and Wang, C. and Bao, X. and Choudhury, A. and Ulrich, J. D. and Holtzman, D. M.}, title = {{Selective reduction of astrocyte apoE3 and apoE4 strongly reduces Aβ accumulation and plaque-related pathology in a mouse model of amyloidosis}}, journal = {Molecular neurodegeneration}, year = {2022}, doi = {10.1186/s13024-022-00516-0}, pmid = {35109920}, url = {https://doi.org/10.1186/s13024-022-00516-0} } @article{esparza2013-23225543, author = {Esparza, T. J. and Zhao, H. and Cirrito, JR. and Cairns, N. J. and Bateman, R. J. and Holtzman, D. M. and Brody, D. L.}, title = {{Amyloid-β oligomerization in Alzheimer dementia versus high-pathology controls}}, journal = {Annals of neurology}, year = {2013}, doi = {10.1002/ana.23748}, pmid = {23225543}, url = {https://doi.org/10.1002/ana.23748} } @article{musiek2015-25766617, author = {Musiek, E. S. and Xiong, D. D. and Holtzman, D. M.}, title = {{Sleep, circadian rhythms, and the pathogenesis of Alzheimer disease}}, journal = {Experimental \& molecular medicine}, year = {2015}, doi = {10.1038/emm.2014.121}, pmid = {25766617}, url = {https://doi.org/10.1038/emm.2014.121} } @article{holtzman2012-22393530, author = {Holtzman, D. M. and Herz, J. and Bu, G.}, title = {{Apolipoprotein E and apolipoprotein E receptors: normal biology and roles in Alzheimer disease}}, journal = {Cold Spring Harbor perspectives in medicine}, year = {2012}, doi = {10.1101/cshperspect.a006312}, pmid = {22393530}, url = {https://doi.org/10.1101/cshperspect.a006312} } @article{wang2013-23959173, author = {Wang, L. and Brier, M. R. and Snyder, A. Z. and Thomas, J. B. and Fagan, A. M. and Xiong, C. and Benzinger, T. L. and Holtzman, D. M. and others}, title = {{Cerebrospinal fluid Aβ42, phosphorylated Tau181, and resting-state functional connectivity}}, journal = {JAMA neurology}, year = {2013}, doi = {10.1001/jamaneurol.2013.3253}, pmid = {23959173}, url = {https://doi.org/10.1001/jamaneurol.2013.3253} } @article{kanekiyo2013-24305823, author = {Kanekiyo, T. and Cirrito, JR. and Liu, C. C. and Shinohara, M. and Li, J. and Schuler, D. R. and Holtzman, D. M. and others}, title = {{Neuronal clearance of amyloid-β by endocytic receptor LRP1}}, journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience}, year = {2013}, doi = {10.1523/jneurosci.3487-13.2013}, pmid = {24305823}, url = {https://doi.org/10.1523/jneurosci.3487-13.2013} } @article{wahrle2005-16207708, author = {Wahrle, S. E. and Jiang, H. and Parsadanian, M. and Hartman, R. E. and Bales, K. R. and Paul, S. M. and Holtzman, D. M.}, title = {{Deletion of Abca1 increases Abeta deposition in the PDAPP transgenic mouse model of Alzheimer disease}}, journal = {The Journal of biological chemistry}, year = {2005}, doi = {10.1074/jbc.m508780200}, pmid = {16207708}, url = {https://doi.org/10.1074/jbc.m508780200} } @article{basak2012-22383525, author = {Basak, J. M. and Verghese, P. B. and Yoon, H. and Kim, J. and Holtzman, D. M.}, title = {{Low-density lipoprotein receptor represents an apolipoprotein E-independent pathway of Aβ uptake and degradation by astrocytes}}, journal = {The Journal of biological chemistry}, year = {2012}, doi = {10.1074/jbc.m111.288746}, pmid = {22383525}, url = {https://doi.org/10.1074/jbc.m111.288746} } @article{noh2026-42676462, author = {Noh, M. Y. and Sung, W. and Kim, H. and Son, B. and Kim, Y. E. and Choi, Y. Y. and Holtzman, D. M. and Kim, S. H.}, title = {{Lecanemab in symptomatic PSEN1 p.Met233Val early-onset Alzheimer's disease: Neuroimaging safety, regional amyloid-PET dynamics, and longitudinal plasma biomarkers}}, journal = {Alzheimer's \& dementia (Amsterdam, Netherlands)}, year = {2026}, doi = {10.1002/dad2.70468}, pmid = {42676462}, url = {https://doi.org/10.1002/dad2.70468} } @article{ulrich2016-26854967, author = {Ulrich, J. D. and Holtzman, D. M.}, title = {{TREM2 Function in Alzheimer's Disease and Neurodegeneration}}, journal = {ACS chemical neuroscience}, year = {2016}, doi = {10.1021/acschemneuro.5b00313}, pmid = {26854967}, url = {https://doi.org/10.1021/acschemneuro.5b00313} }