% alzhub.org library filter % Source: https://alzhub.org/research?category=genetics&author=Holtzman+DM&status=peer-reviewed % 19 entries, in the order the page lists them. Built from alzhub.org's own records. % 0 entries have no readable author in the source record and carry no author field. @article{piccio2016-26754641, author = {Piccio, L. and Deming, Y. and Del-Águila, J. L. and Ghezzi, L. and Holtzman, D. M. and Fagan, A. M. and Fenoglio, C. and Galimberti, D. and others}, title = {{Cerebrospinal fluid soluble TREM2 is higher in Alzheimer disease and associated with mutation status}}, journal = {Acta neuropathologica}, year = {2016}, doi = {10.1007/s00401-016-1533-5}, pmid = {26754641}, url = {https://doi.org/10.1007/s00401-016-1533-5} } @article{morris2010-20186853, author = {Morris, J. C. and Roe, C. M. and Xiong, C. and Fagan, A. M. and Goate, A. M. and Holtzman, D. M. and Mintun, M. A.}, title = {{APOE predicts amyloid-beta but not tau Alzheimer pathology in cognitively normal aging}}, journal = {Annals of neurology}, year = {2010}, doi = {10.1002/ana.21843}, pmid = {20186853}, url = {https://doi.org/10.1002/ana.21843} } @article{mishra2018-29672664, author = {Mishra, S. and Blazey, T. M. and Holtzman, D. M. and Cruchaga, C. and Su, Y. and Morris, J. C. and Benzinger, T. L. S. and Gordon, B. A.}, title = {{Longitudinal brain imaging in preclinical Alzheimer disease: impact of APOE ε4 genotype}}, journal = {Brain : a journal of neurology}, year = {2018}, doi = {10.1093/brain/awy103}, pmid = {29672664}, url = {https://doi.org/10.1093/brain/awy103} } @article{hu2012-22855860, author = {Hu, W. T. and Holtzman, D. M. and Fagan, A. M. and Shaw, L. M. and Perrin, R. and Arnold, S. E. and Grossman, M. and Xiong, C. and others}, title = {{Plasma multianalyte profiling in mild cognitive impairment and Alzheimer disease}}, journal = {Neurology}, year = {2012}, doi = {10.1212/wnl.0b013e318266fa70}, pmid = {22855860}, url = {https://doi.org/10.1212/wnl.0b013e318266fa70} } @article{deane2008-19033669, author = {Deane, R. and Sagare, A. and Hamm, K. and Parisi, M. and Lane, S. and Finn, M. B. and Holtzman, D. M. and Zlokovic, B. V.}, title = {{apoE isoform-specific disruption of amyloid beta peptide clearance from mouse brain}}, journal = {The Journal of clinical investigation}, year = {2008}, doi = {10.1172/jci36663}, pmid = {19033669}, url = {https://doi.org/10.1172/jci36663} } @article{shi2018-30140051, author = {Shi, Y. and Holtzman, D. M.}, title = {{Interplay between innate immunity and Alzheimer disease: APOE and TREM2 in the spotlight}}, journal = {Nature reviews. Immunology}, year = {2018}, doi = {10.1038/s41577-018-0051-1}, pmid = {30140051}, url = {https://doi.org/10.1038/s41577-018-0051-1} } @article{chen2021-33176118, author = {Chen, Y. and Strickland, M. R. and Soranno, A. and Holtzman, D. M.}, title = {{Apolipoprotein E: Structural Insights and Links to Alzheimer Disease Pathogenesis}}, journal = {Neuron}, year = {2021}, doi = {10.1016/j.neuron.2020.10.008}, pmid = {33176118}, url = {https://doi.org/10.1016/j.neuron.2020.10.008} } @article{holtzman2012-22393530, author = {Holtzman, D. M. and Herz, J. and Bu, G.}, title = {{Apolipoprotein E and apolipoprotein E receptors: normal biology and roles in Alzheimer disease}}, journal = {Cold Spring Harbor perspectives in medicine}, year = {2012}, doi = {10.1101/cshperspect.a006312}, pmid = {22393530}, url = {https://doi.org/10.1101/cshperspect.a006312} } @article{wahrle2005-16207708, author = {Wahrle, S. E. and Jiang, H. and Parsadanian, M. and Hartman, R. E. and Bales, K. R. and Paul, S. M. and Holtzman, D. M.}, title = {{Deletion of Abca1 increases Abeta deposition in the PDAPP transgenic mouse model of Alzheimer disease}}, journal = {The Journal of biological chemistry}, year = {2005}, doi = {10.1074/jbc.m508780200}, pmid = {16207708}, url = {https://doi.org/10.1074/jbc.m508780200} } @article{basak2012-22383525, author = {Basak, J. M. and Verghese, P. B. and Yoon, H. and Kim, J. and Holtzman, D. M.}, title = {{Low-density lipoprotein receptor represents an apolipoprotein E-independent pathway of Aβ uptake and degradation by astrocytes}}, journal = {The Journal of biological chemistry}, year = {2012}, doi = {10.1074/jbc.m111.288746}, pmid = {22383525}, url = {https://doi.org/10.1074/jbc.m111.288746} } @article{holtzman1995-7568158, author = {Holtzman, D. M. and Pitas, R. E. and Kilbridge, J. and Nathan, B. and Mahley, R. W. and Bu, G. and Schwartz, A. L.}, title = {{Low density lipoprotein receptor-related protein mediates apolipoprotein E-dependent neurite outgrowth in a central nervous system-derived neuronal cell line}}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, year = {1995}, doi = {10.1073/pnas.92.21.9480}, pmid = {7568158}, url = {https://doi.org/10.1073/pnas.92.21.9480} } @article{zerbinatti2006-17012232, author = {Zerbinatti, C. V. and Wahrle, S. E. and Kim, H. and Cam, J. A. and Bales, K. and Paul, S. M. and Holtzman, D. M. and Bu, G.}, title = {{Apolipoprotein E and low density lipoprotein receptor-related protein facilitate intraneuronal Abeta42 accumulation in amyloid model mice}}, journal = {The Journal of biological chemistry}, year = {2006}, doi = {10.1074/jbc.m604436200}, pmid = {17012232}, url = {https://doi.org/10.1074/jbc.m604436200} } @article{wang2021-34385305, author = {Wang, H. and Kulas, J. A. and Wang, C. and Holtzman, D. M. and Ferris, H. A. and Hansen, S. B.}, title = {{Regulation of beta-amyloid production in neurons by astrocyte-derived cholesterol}}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, year = {2021}, doi = {10.1073/pnas.2102191118}, pmid = {34385305}, url = {https://doi.org/10.1073/pnas.2102191118} } @article{holtzman2000-10852539, author = {Holtzman, D. M. and Fagan, A. M. and Mackey, B. and Tenkova, T. and Sartorius, L. and Paul, S. M. and Bales, K. and Ashe, K. H. and others}, title = {{Apolipoprotein E facilitates neuritic and cerebrovascular plaque formation in an Alzheimer's disease model}}, journal = {Annals of neurology}, year = {2000}, doi = {10.1002/1531-8249(200006)47:6<739::aid-ana6>3.0.co;2-8}, pmid = {10852539}, url = {https://doi.org/10.1002/1531-8249(200006)47:6<739::aid-ana6>3.0.co;2-8} } @article{bales2002-14993413, author = {Bales, K. R. and Dodart, J. C. and DeMattos, R. B. and Holtzman, D. M. and Paul, S. M.}, title = {{Apolipoprotein E, amyloid, and Alzheimer disease}}, journal = {Molecular interventions}, year = {2002}, doi = {10.1124/mi.2.6.363}, pmid = {14993413}, url = {https://doi.org/10.1124/mi.2.6.363} } @article{shibata2000-11120756, author = {Shibata, M. and Yamada, S. and Kumar, SR. and Calero, M. and Bading, J. and Frangione, B. and Holtzman, D. M. and Miller, C. A. and others}, title = {{Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier}}, journal = {The Journal of clinical investigation}, year = {2000}, doi = {10.1172/jci10498}, pmid = {11120756}, url = {https://doi.org/10.1172/jci10498} } @article{bell2007-17077814, author = {Bell, R. D. and Sagare, A. P. and Friedman, A. E. and Bedi, G. S. and Holtzman, D. M. and Deane, R. and Zlokovic, B. V.}, title = {{Transport pathways for clearance of human Alzheimer's amyloid beta-peptide and apolipoproteins E and J in the mouse central nervous system}}, journal = {Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism}, year = {2007}, doi = {10.1038/sj.jcbfm.9600419}, pmid = {17077814}, url = {https://doi.org/10.1038/sj.jcbfm.9600419} } @article{holtzman1999-10079115, author = {Holtzman, D. M. and Bales, K. R. and Wu, S. and Bhat, P. and Parsadanian, M. and Fagan, A. M. and Chang, L. K. and Sun, Y. and others}, title = {{Expression of human apolipoprotein E reduces amyloid-beta deposition in a mouse model of Alzheimer's disease}}, journal = {The Journal of clinical investigation}, year = {1999}, doi = {10.1172/jci6179}, pmid = {10079115}, url = {https://doi.org/10.1172/jci6179} } @article{fagan2002-11950276, author = {Fagan, A. M. and Watson, M. and Parsadanian, M. and Bales, K. R. and Paul, S. M. and Holtzman, D. M.}, title = {{Human and murine ApoE markedly alters A beta metabolism before and after plaque formation in a mouse model of Alzheimer's disease}}, journal = {Neurobiology of disease}, year = {2002}, doi = {10.1006/nbdi.2002.0483}, pmid = {11950276}, url = {https://doi.org/10.1006/nbdi.2002.0483} }