% alzhub.org library filter
% Source: https://alzhub.org/research?author=Head+E
% 47 entries, in the order the page lists them. Built from alzhub.org's own records.
% 0 entries have no readable author in the source record and carry no author field.

@article{wisch2024-38631766,
  author  = {Wisch, J. K. and McKay, N. S. and Boerwinkle, A. H. and Kennedy, J. and Flores, S. and Handen, B. L. and Christian, B. T. and Head, E. and others},
  title   = {{Comparison of tau spread in people with Down syndrome versus autosomal-dominant Alzheimer's disease: a cross-sectional study}},
  journal = {The Lancet. Neurology},
  year    = {2024},
  doi     = {10.1016/s1474-4422(24)00084-x},
  pmid    = {38631766},
  url     = {https://doi.org/10.1016/s1474-4422(24)00084-x}
}

@article{lott2011-21739598,
  author  = {Lott, I. T. and Doran, E. and Nguyen, V. Q. and Tournay, A. and Head, E. and Gillen, D. L.},
  title   = {{Down syndrome and dementia: a randomized, controlled trial of antioxidant supplementation}},
  journal = {American journal of medical genetics. Part A},
  year    = {2011},
  doi     = {10.1002/ajmg.a.34114},
  pmid    = {21739598},
  url     = {https://doi.org/10.1002/ajmg.a.34114}
}

@article{lott2019-30733618,
  author  = {Lott, I. T. and Head, E.},
  title   = {{Dementia in Down syndrome: unique insights for Alzheimer disease research}},
  journal = {Nature reviews. Neurology},
  year    = {2019},
  doi     = {10.1038/s41582-018-0132-6},
  pmid    = {30733618},
  url     = {https://doi.org/10.1038/s41582-018-0132-6}
}

@article{fortea2021-34687637,
  author  = {Fortea, J. and Zaman, S. H. and Hartley, S. and Rafii, M. S. and Head, E. and Carmona-Iragui, M.},
  title   = {{Alzheimer's disease associated with Down syndrome: a genetic form of dementia}},
  journal = {The Lancet. Neurology},
  year    = {2021},
  doi     = {10.1016/s1474-4422(21)00245-3},
  pmid    = {34687637},
  url     = {https://doi.org/10.1016/s1474-4422(21)00245-3}
}

@article{head2009-19703441,
  author  = {Head, E. and Nukala, V. N. and Fenoglio, K. A. and Muggenburg, B. A. and Cotman, C. W. and Sullivan, P. G.},
  title   = {{Effects of age, dietary, and behavioral enrichment on brain mitochondria in a canine model of human aging}},
  journal = {Experimental neurology},
  year    = {2009},
  doi     = {10.1016/j.expneurol.2009.08.014},
  pmid    = {19703441},
  url     = {https://doi.org/10.1016/j.expneurol.2009.08.014}
}

@article{nelson2011-21516511,
  author  = {Nelson, P. T. and Head, E. and Schmitt, F. A. and Davis, P. R. and Neltner, J. H. and Jicha, G. A. and Abner, E. L. and Smith, C. D. and others},
  title   = {{Alzheimer's disease is not "brain aging": neuropathological, genetic, and epidemiological human studies}},
  journal = {Acta neuropathologica},
  year    = {2011},
  doi     = {10.1007/s00401-011-0826-y},
  pmid    = {21516511},
  url     = {https://doi.org/10.1007/s00401-011-0826-y}
}

@article{head2017-29195510,
  author  = {Head, E. and Phelan, M. J. and Doran, E. and Kim, R. C. and Poon, W. W. and Schmitt, F. A. and Lott, I. T.},
  title   = {{Cerebrovascular pathology in Down syndrome and Alzheimer disease}},
  journal = {Acta neuropathologica communications},
  year    = {2017},
  doi     = {10.1186/s40478-017-0499-4},
  pmid    = {29195510},
  url     = {https://doi.org/10.1186/s40478-017-0499-4}
}

@article{berlau2009-19255410,
  author  = {Berlau, D. J. and Corrada, M. M. and Head, E. and Kawas, C. H.},
  title   = {{APOE epsilon2 is associated with intact cognition but increased Alzheimer pathology in the oldest old}},
  journal = {Neurology},
  year    = {2009},
  doi     = {10.1212/01.wnl.0000343853.00346.a4},
  pmid    = {19255410},
  url     = {https://doi.org/10.1212/01.wnl.0000343853.00346.a4}
}

@article{clina2026-41561734,
  author  = {Clina, J. G. and Helsel, B. C. and Hartley, S. L. and White, D. A. and Fleming-Batayneh, V. L. and Handen, B. and Christian, B. and Head, E. and others},
  title   = {{The impact of congenital heart disease on the timing of Alzheimer's disease in Down syndrome}},
  journal = {Alzheimer's \& dementia (Amsterdam, Netherlands)},
  year    = {2026},
  doi     = {10.1002/dad2.70257},
  pmid    = {41561734},
  url     = {https://doi.org/10.1002/dad2.70257}
}

@article{head2018-29977201,
  author  = {Head, E. and Powell, D. K. and Schmitt, F. A.},
  title   = {{Metabolic and Vascular Imaging Biomarkers in Down Syndrome Provide Unique Insights Into Brain Aging and Alzheimer Disease Pathogenesis}},
  journal = {Frontiers in aging neuroscience},
  year    = {2018},
  doi     = {10.3389/fnagi.2018.00191},
  pmid    = {29977201},
  url     = {https://doi.org/10.3389/fnagi.2018.00191}
}

@article{dass2025-41104603,
  author  = {Dass, D. and Dang, L. T. and Xicota, L. and Krinsky-McHale, S. and Kannappan, B. and Brickman, A. M. and Christian, B. T. and Head, E. and others},
  title   = {{Examination of metabolic syndrome in Down syndrome and association with dementia}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2025},
  doi     = {10.1002/alz.70799},
  pmid    = {41104603},
  url     = {https://doi.org/10.1002/alz.70799}
}

@article{head2016-26651341,
  author  = {Head, E. and Lott, I. T. and Wilcock, D. M. and Lemere, C. A.},
  title   = {{Aging in Down Syndrome and the Development of Alzheimer's Disease Neuropathology}},
  journal = {Current Alzheimer research},
  year    = {2016},
  doi     = {10.2174/1567205012666151020114607},
  pmid    = {26651341},
  url     = {https://doi.org/10.2174/1567205012666151020114607}
}

@article{vanderlip2026-42825390,
  author  = {Vanderlip, C. R. and Hartley, S. L. and Krinsky-McHale, S. and Hom, C. and Brickman, A. M. and Petersen, M. E. and Head, E. and Stark, C. E. L. and others},
  title   = {{Memory and Plasma pTau217 Refine Prognosis in Down Syndrome}},
  journal = {Annals of neurology},
  year    = {2026},
  doi     = {10.1002/ana.78366},
  pmid    = {42825390},
  url     = {https://doi.org/10.1002/ana.78366}
}

@article{abdelmoity2025-40977577,
  author  = {Abdelmoity, O. and Wisch, J. K. and Kennedy, J. T. and Goyal, M. and Vlassenko, A. and Flores, S. and Handen, B. L. and Head, E. and others},
  title   = {{Cross-Sectional FDG in Down Syndrome and Autosomal Dominant Alzheimer's Disease}},
  journal = {Annals of neurology},
  year    = {2025},
  doi     = {10.1002/ana.78002},
  pmid    = {40977577},
  url     = {https://doi.org/10.1002/ana.78002}
}

@article{perluigi2014-24735980,
  author  = {Perluigi, M. and Pupo, G. and Tramutola, A. and Cini, C. and Coccia, R. and Barone, E. and Head, E. and Butterfield, D. A. and others},
  title   = {{Neuropathological role of PI3K/Akt/mTOR axis in Down syndrome brain}},
  journal = {Biochimica et biophysica acta},
  year    = {2014},
  doi     = {10.1016/j.bbadis.2014.04.007},
  pmid    = {24735980},
  url     = {https://doi.org/10.1016/j.bbadis.2014.04.007}
}

@article{butterfield2014-25242166,
  author  = {Butterfield, D. A. and Di Domenico, F. and Swomley, A. M. and Head, E. and Perluigi, M.},
  title   = {{Redox proteomics analysis to decipher the neurobiology of Alzheimer-like neurodegeneration: overlaps in Down's syndrome and Alzheimer's disease brain}},
  journal = {The Biochemical journal},
  year    = {2014},
  doi     = {10.1042/bj20140772},
  pmid    = {25242166},
  url     = {https://doi.org/10.1042/bj20140772}
}

@article{didomenico2018-28807816,
  author  = {Di Domenico, F. and Tramutola, A. and Foppoli, C. and Head, E. and Perluigi, M. and Butterfield, D. A.},
  title   = {{mTOR in Down syndrome: Role in Aß and tau neuropathology and transition to Alzheimer disease-like dementia}},
  journal = {Free radical biology \& medicine},
  year    = {2018},
  doi     = {10.1016/j.freeradbiomed.2017.08.009},
  pmid    = {28807816},
  url     = {https://doi.org/10.1016/j.freeradbiomed.2017.08.009}
}

@article{tramutola2020-31987911,
  author  = {Tramutola, A. and Lanzillotta, C. and Di Domenico, F. and Head, E. and Butterfield, D. A. and Perluigi, M. and Barone, E.},
  title   = {{Brain insulin resistance triggers early onset Alzheimer disease in Down syndrome}},
  journal = {Neurobiology of disease},
  year    = {2020},
  doi     = {10.1016/j.nbd.2020.104772},
  pmid    = {31987911},
  url     = {https://doi.org/10.1016/j.nbd.2020.104772}
}

@article{nelson2005-15795053,
  author  = {Nelson, L. and Johnson, J. K. and Freedman, M. and Lott, I. and Groot, J. and Chang, M. and Milgram, N. W. and Head, E.},
  title   = {{Learning and memory as a function of age in Down syndrome: a study using animal-based tasks}},
  journal = {Progress in neuro-psychopharmacology \& biological psychiatry},
  year    = {2005},
  doi     = {10.1016/j.pnpbp.2004.12.009},
  pmid    = {15795053},
  url     = {https://doi.org/10.1016/j.pnpbp.2004.12.009}
}

@article{tomic2009-19523517,
  author  = {Tomic, J. L. and Pensalfini, A. and Head, E. and Glabe, C. G.},
  title   = {{Soluble fibrillar oligomer levels are elevated in Alzheimer's disease brain and correlate with cognitive dysfunction}},
  journal = {Neurobiology of disease},
  year    = {2009},
  doi     = {10.1016/j.nbd.2009.05.024},
  pmid    = {19523517},
  url     = {https://doi.org/10.1016/j.nbd.2009.05.024}
}

@article{lott2005-15639317,
  author  = {Lott, I. T. and Head, E.},
  title   = {{Alzheimer disease and Down syndrome: factors in pathogenesis}},
  journal = {Neurobiology of aging},
  year    = {2005},
  doi     = {10.1016/j.neurobiolaging.2004.08.005},
  pmid    = {15639317},
  url     = {https://doi.org/10.1016/j.neurobiolaging.2004.08.005}
}

@article{didomenico2014-24675226,
  author  = {Di Domenico, F. and Pupo, G. and Tramutola, A. and Giorgi, A. and Schininà, M. E. and Coccia, R. and Head, E. and Butterfield, D. A. and others},
  title   = {{Redox proteomics analysis of HNE-modified proteins in Down syndrome brain: clues for understanding the development of Alzheimer disease}},
  journal = {Free radical biology \& medicine},
  year    = {2014},
  doi     = {10.1016/j.freeradbiomed.2014.03.027},
  pmid    = {24675226},
  url     = {https://doi.org/10.1016/j.freeradbiomed.2014.03.027}
}

@article{head2003-14533781,
  author  = {Head, E. and Lott, I. T. and Hof, P. R. and Bouras, C. and Su, J. H. and Kim, R. and Haier, R. and Cotman, C. W.},
  title   = {{Parallel compensatory and pathological events associated with tau pathology in middle aged individuals with Down syndrome}},
  journal = {Journal of neuropathology and experimental neurology},
  year    = {2003},
  doi     = {10.1093/jnen/62.9.917},
  pmid    = {14533781},
  url     = {https://doi.org/10.1093/jnen/62.9.917}
}

@article{morabito2021-34239132,
  author  = {Morabito, S. and Miyoshi, E. and Michael, N. and Shahin, S. and Martini, A. C. and Head, E. and Silva, J. and Leavy, K. and others},
  title   = {{Single-nucleus chromatin accessibility and transcriptomic characterization of Alzheimer's disease}},
  journal = {Nature genetics},
  year    = {2021},
  doi     = {10.1038/s41588-021-00894-z},
  pmid    = {34239132},
  url     = {https://doi.org/10.1038/s41588-021-00894-z}
}

@article{doran2017-27983553,
  author  = {Doran, E. and Keator, D. and Head, E. and Phelan, M. J. and Kim, R. and Totoiu, M. and Barrio, JR. and Small, G. W. and others},
  title   = {{Down Syndrome, Partial Trisomy 21, and Absence of Alzheimer's Disease: The Role of APP}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2017},
  doi     = {10.3233/jad-160836},
  pmid    = {27983553},
  url     = {https://doi.org/10.3233/jad-160836}
}

@article{barone2018-28705658,
  author  = {Barone, E. and Arena, A. and Head, E. and Butterfield, D. A. and Perluigi, M.},
  title   = {{Disturbance of redox homeostasis in Down Syndrome: Role of iron dysmetabolism}},
  journal = {Free radical biology \& medicine},
  year    = {2018},
  doi     = {10.1016/j.freeradbiomed.2017.07.009},
  pmid    = {28705658},
  url     = {https://doi.org/10.1016/j.freeradbiomed.2017.07.009}
}

@article{barone2017-27838436,
  author  = {Barone, E. and Head, E. and Butterfield, D. A. and Perluigi, M.},
  title   = {{HNE-modified proteins in Down syndrome: Involvement in development of Alzheimer disease neuropathology}},
  journal = {Free radical biology \& medicine},
  year    = {2017},
  doi     = {10.1016/j.freeradbiomed.2016.10.508},
  pmid    = {27838436},
  url     = {https://doi.org/10.1016/j.freeradbiomed.2016.10.508}
}

@article{dohl2025-40042516,
  author  = {Dohl, J. and Treadwell, Z. and Norris, C. and Head, E.},
  title   = {{Calcineurin inhibition may prevent Alzheimer disease in people with Down syndrome}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2025},
  doi     = {10.1002/alz.70034},
  pmid    = {40042516},
  url     = {https://doi.org/10.1002/alz.70034}
}

@article{head2007-17361036,
  author  = {Head, E. and Lott, I. T. and Patterson, D. and Doran, E. and Haier, R. J.},
  title   = {{Possible compensatory events in adult Down syndrome brain prior to the development of Alzheimer disease neuropathology: targets for nonpharmacological intervention}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2007},
  doi     = {10.3233/jad-2007-11110},
  pmid    = {17361036},
  url     = {https://doi.org/10.3233/jad-2007-11110}
}

@article{helman2019-30452414,
  author  = {Helman, A. M. and Siever, M. and McCarty, K. L. and Lott, I. T. and Doran, E. and Abner, E. L. and Schmitt, F. A. and Head, E.},
  title   = {{Microbleeds and Cerebral Amyloid Angiopathy in the Brains of People with Down Syndrome with Alzheimer's Disease}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2019},
  doi     = {10.3233/jad-180589},
  pmid    = {30452414},
  url     = {https://doi.org/10.3233/jad-180589}
}

@article{lott2001-11553933,
  author  = {Lott, I. T. and Head, E.},
  title   = {{Down syndrome and Alzheimer's disease: a link between development and aging}},
  journal = {Mental retardation and developmental disabilities research reviews},
  year    = {2001},
  doi     = {10.1002/mrdd.1025},
  pmid    = {11553933},
  url     = {https://doi.org/10.1002/mrdd.1025}
}

@article{martini2022-35472307,
  author  = {Martini, A. C. and Gross, T. J. and Head, E. and Mapstone, M.},
  title   = {{Beyond amyloid: Immune, cerebrovascular, and metabolic contributions to Alzheimer disease in people with Down syndrome}},
  journal = {Neuron},
  year    = {2022},
  doi     = {10.1016/j.neuron.2022.04.001},
  pmid    = {35472307},
  url     = {https://doi.org/10.1016/j.neuron.2022.04.001}
}

@article{clina2025-41100837,
  author  = {Clina, J. G. and Helsel, B. C. and Hartley, S. L. and Fleming-Batayneh, V. L. and Handen, B. and Christian, B. and Head, E. and Mapstone, M. and others},
  title   = {{The joint association of obesity and physical activity on cognitive function in Down syndrome}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2025},
  doi     = {10.1177/13872877251386474},
  pmid    = {41100837},
  url     = {https://doi.org/10.1177/13872877251386474}
}

@article{kayed2007-17897471,
  author  = {Kayed, R. and Head, E. and Sarsoza, F. and Saing, T. and Cotman, C. W. and Necula, M. and Margol, L. and Wu, J. and others},
  title   = {{Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomers}},
  journal = {Molecular neurodegeneration},
  year    = {2007},
  doi     = {10.1186/1750-1326-2-18},
  pmid    = {17897471},
  url     = {https://doi.org/10.1186/1750-1326-2-18}
}

@article{lott2006-17168651,
  author  = {Lott, I. T. and Head, E. and Doran, E. and Busciglio, J.},
  title   = {{Beta-amyloid, oxidative stress and down syndrome}},
  journal = {Current Alzheimer research},
  year    = {2006},
  doi     = {10.2174/156720506779025305},
  pmid    = {17168651},
  url     = {https://doi.org/10.2174/156720506779025305}
}

@article{cenini2014-25151119,
  author  = {Cenini, G. and Fiorini, A. and Sultana, R. and Perluigi, M. and Cai, J. and Klein, J. B. and Head, E. and Butterfield, D. A.},
  title   = {{An investigation of the molecular mechanisms engaged before and after the development of Alzheimer disease neuropathology in Down syndrome: a proteomics approach}},
  journal = {Free radical biology \& medicine},
  year    = {2014},
  doi     = {10.1016/j.freeradbiomed.2014.08.006},
  pmid    = {25151119},
  url     = {https://doi.org/10.1016/j.freeradbiomed.2014.08.006}
}

@article{head2012-25285303,
  author  = {Head, E. and Powell, D. and Gold, B. T. and Schmitt, F. A.},
  title   = {{Alzheimer's Disease in Down Syndrome}},
  journal = {European journal of neurodegenerative disease},
  year    = {2012},
  pmid    = {25285303}
}

@article{reeves2019-30800043,
  author  = {Reeves, R. H. and Delabar, J. and Potier, M. C. and Bhattacharyya, A. and Head, E. and Lemere, C. and Dekker, A. D. and De Deyn, P. and others},
  title   = {{Paving the Way for Therapy: The Second International Conference of the Trisomy 21 Research Society}},
  journal = {Molecular syndromology},
  year    = {2019},
  doi     = {10.1159/000494231},
  pmid    = {30800043},
  url     = {https://doi.org/10.1159/000494231}
}

@article{head2009-18006193,
  author  = {Head, E. and Corrada, M. M. and Kahle-Wrobleski, K. and Kim, R. C. and Sarsoza, F. and Goodus, M. and Kawas, C. H.},
  title   = {{Synaptic proteins, neuropathology and cognitive status in the oldest-old}},
  journal = {Neurobiology of aging},
  year    = {2009},
  doi     = {10.1016/j.neurobiolaging.2007.10.001},
  pmid    = {18006193},
  url     = {https://doi.org/10.1016/j.neurobiolaging.2007.10.001}
}

@article{tapp2004-15385603,
  author  = {Tapp, P. D. and Siwak, C. T. and Gao, F. Q. and Chiou, J. Y. and Black, S. E. and Head, E. and Muggenburg, B. A. and Cotman, C. W. and others},
  title   = {{Frontal lobe volume, function, and beta-amyloid pathology in a canine model of aging}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2004},
  doi     = {10.1523/jneurosci.1339-04.2004},
  pmid    = {15385603},
  url     = {https://doi.org/10.1523/jneurosci.1339-04.2004}
}

@article{head2010-20164551,
  author  = {Head, E. and Pop, V. and Sarsoza, F. and Kayed, R. and Beckett, T. L. and Studzinski, C. M. and Tomic, J. L. and Glabe, C. G. and others},
  title   = {{Amyloid-beta peptide and oligomers in the brain and cerebrospinal fluid of aged canines}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2010},
  doi     = {10.3233/jad-2010-1397},
  pmid    = {20164551},
  url     = {https://doi.org/10.3233/jad-2010-1397}
}

@article{didomenico2013-23603808,
  author  = {Di Domenico, F. and Coccia, R. and Cocciolo, A. and Murphy, M. P. and Cenini, G. and Head, E. and Butterfield, D. A. and Giorgi, A. and others},
  title   = {{Impairment of proteostasis network in Down syndrome prior to the development of Alzheimer's disease neuropathology: redox proteomics analysis of human brain}},
  journal = {Biochimica et biophysica acta},
  year    = {2013},
  doi     = {10.1016/j.bbadis.2013.04.013},
  pmid    = {23603808},
  url     = {https://doi.org/10.1016/j.bbadis.2013.04.013}
}

@article{coskun2010-20463402,
  author  = {Coskun, P. E. and Wyrembak, J. and Derbereva, O. and Melkonian, G. and Doran, E. and Lott, I. T. and Head, E. and Cotman, C. W. and others},
  title   = {{Systemic mitochondrial dysfunction and the etiology of Alzheimer's disease and down syndrome dementia}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2010},
  doi     = {10.3233/jad-2010-100351},
  pmid    = {20463402},
  url     = {https://doi.org/10.3233/jad-2010-100351}
}

@article{mouser2006-16507909,
  author  = {Mouser, P. E. and Head, E. and Ha, K. H. and Rohn, T. T.},
  title   = {{Caspase-mediated cleavage of glial fibrillary acidic protein within degenerating astrocytes of the Alzheimer's disease brain}},
  journal = {The American journal of pathology},
  year    = {2006},
  doi     = {10.2353/ajpath.2006.050798},
  pmid    = {16507909},
  url     = {https://doi.org/10.2353/ajpath.2006.050798}
}

@article{karim2026-9885f5da,
  author  = {Karim, F. and Chavez-Jacobo, N. P. and Liang, C. and Head, E. and Mukherjee, J.},
  title   = {{Down syndrome postmortem brains exhibit reduction in [ 18 F]nifene binding to α4β2* nicotinic acetylcholinergic receptors}},
  journal = {bioRxiv},
  year    = {2026},
  doi     = {10.64898/2026.09.09.750420},
  url     = {https://doi.org/10.64898/2026.09.09.750420}
}

@article{song2026-c369392a,
  author  = {Song, Z. and Song, S. and Clare, I. C. and Head, E. and Hom, C. L. and Brickman, A. M. and Hartley, S. and Lao, P. J. and others},
  title   = {{Multi-dimensional attention framework for personalised Alzheimer's disease progression prediction across sporadic and genetic risk cohorts}},
  journal = {Research Square},
  year    = {2026},
  doi     = {10.21203/rs.3.rs-10309496/v1},
  url     = {https://doi.org/10.21203/rs.3.rs-10309496/v1}
}

@article{biju2026-e14002dc,
  author  = {Biju, A. P. and Karim, F. and Schafer, D. M. and Sison, S. A. and Liang, C. and Head, E. and Mukherjee, J.},
  title   = {{Measurement of tau protein and Aβ amyloid plaques in postmortem human brains of Down syndrome and Alzheimer’s disease by using [ 125 I]IPPI and [ 125 I]IBETA autoradiography}},
  journal = {bioRxiv},
  year    = {2026},
  doi     = {10.64898/2026.01.17.700075},
  url     = {https://doi.org/10.64898/2026.01.17.700075}
}