% alzhub.org library filter % Source: https://alzhub.org/research?author=De+Strooper+B % 21 entries, in the order the page lists them. Built from alzhub.org's own records. % 0 entries have no readable author in the source record and carry no author field. @article{scheltens2021-33667416, author = {Scheltens, P. and De Strooper, B. and Kivipelto, M. and Holstege, H. and Chételat, G. and Teunissen, C. E. and Cummings, J. and van der Flier, W. M.}, title = {{Alzheimer's disease}}, journal = {Lancet (London, England)}, year = {2021}, doi = {10.1016/s0140-6736(20)32205-4}, pmid = {33667416}, url = {https://doi.org/10.1016/s0140-6736(20)32205-4} } @article{baligacs2024-39639016, author = {Baligács, N. and Albertini, G. and Borrie, S. C. and Serneels, L. and Pridans, C. and Balusu, S. and De Strooper, B.}, title = {{Homeostatic microglia initially seed and activated microglia later reshape amyloid plaques in Alzheimer's Disease}}, journal = {Nature communications}, year = {2024}, doi = {10.1038/s41467-024-54779-w}, pmid = {39639016}, url = {https://doi.org/10.1038/s41467-024-54779-w} } @article{karran2022-35177833, author = {Karran, E. and De Strooper, B.}, title = {{The amyloid hypothesis in Alzheimer disease: new insights from new therapeutics}}, journal = {Nature reviews. Drug discovery}, year = {2022}, doi = {10.1038/s41573-022-00391-w}, pmid = {35177833}, url = {https://doi.org/10.1038/s41573-022-00391-w} } @article{destrooper2016-26871627, author = {De Strooper, B. and Karran, E.}, title = {{The Cellular Phase of Alzheimer's Disease}}, journal = {Cell}, year = {2016}, doi = {10.1016/j.cell.2015.12.056}, pmid = {26871627}, url = {https://doi.org/10.1016/j.cell.2015.12.056} } @article{sierksma2020-33004512, author = {Sierksma, A. and Escott-Price, V. and De Strooper, B.}, title = {{Translating genetic risk of Alzheimer's disease into mechanistic insight and drug targets}}, journal = {Science (New York, N.Y.)}, year = {2020}, doi = {10.1126/science.abb8575}, pmid = {33004512}, url = {https://doi.org/10.1126/science.abb8575} } @article{destrooper2010-20139999, author = {De Strooper, B. and Vassar, R. and Golde, T.}, title = {{The secretases: enzymes with therapeutic potential in Alzheimer disease}}, journal = {Nature reviews. Neurology}, year = {2010}, doi = {10.1038/nrneurol.2009.218}, pmid = {20139999}, url = {https://doi.org/10.1038/nrneurol.2009.218} } @article{mcdade2021-34548654, author = {McDade, E. and Voytyuk, I. and Aisen, P. and Bateman, R. J. and Carrillo, M. C. and De Strooper, B. and Haass, C. and Reiman, E. M. and others}, title = {{The case for low-level BACE1 inhibition for the prevention of Alzheimer disease}}, journal = {Nature reviews. Neurology}, year = {2021}, doi = {10.1038/s41582-021-00545-1}, pmid = {34548654}, url = {https://doi.org/10.1038/s41582-021-00545-1} } @article{destrooper2007-17268505, author = {De Strooper, B.}, title = {{Loss-of-function presenilin mutations in Alzheimer disease. Talking Point on the role of presenilin mutations in Alzheimer disease}}, journal = {EMBO reports}, year = {2007}, doi = {10.1038/sj.embor.7400897}, pmid = {17268505}, url = {https://doi.org/10.1038/sj.embor.7400897} } @article{destrooper2000-10806097, author = {De Strooper, B. and Annaert, W.}, title = {{Proteolytic processing and cell biological functions of the amyloid precursor protein}}, journal = {Journal of cell science}, year = {2000}, doi = {10.1242/jcs.113.11.1857}, pmid = {10806097}, url = {https://doi.org/10.1242/jcs.113.11.1857} } @article{wong2005-15824102, author = {Wong, H. K. and Sakurai, T. and Oyama, F. and Kaneko, K. and Wada, K. and Miyazaki, H. and Kurosawa, M. and De Strooper, B. and others}, title = {{beta Subunits of voltage-gated sodium channels are novel substrates of beta-site amyloid precursor protein-cleaving enzyme (BACE1) and gamma-secretase}}, journal = {The Journal of biological chemistry}, year = {2005}, doi = {10.1074/jbc.m414648200}, pmid = {15824102}, url = {https://doi.org/10.1074/jbc.m414648200} } @article{kuhn2007-17307738, author = {Kuhn, P. H. and Marjaux, E. and Imhof, A. and De Strooper, B. and Haass, C. and Lichtenthaler, S. F.}, title = {{Regulated intramembrane proteolysis of the interleukin-1 receptor II by alpha-, beta-, and gamma-secretase}}, journal = {The Journal of biological chemistry}, year = {2007}, doi = {10.1074/jbc.m700356200}, pmid = {17307738}, url = {https://doi.org/10.1074/jbc.m700356200} } @article{tolia2006-16844686, author = {Tolia, A. and Chávez-Gutiérrez, L. and De Strooper, B.}, title = {{Contribution of presenilin transmembrane domains 6 and 7 to a water-containing cavity in the gamma-secretase complex}}, journal = {The Journal of biological chemistry}, year = {2006}, doi = {10.1074/jbc.m604997200}, pmid = {16844686}, url = {https://doi.org/10.1074/jbc.m604997200} } @article{brownjohn2017-28285880, author = {Brownjohn, P. W. and Smith, J. and Portelius, E. and Serneels, L. and Kvartsberg, H. and De Strooper, B. and Blennow, K. and Zetterberg, H. and others}, title = {{Phenotypic Screening Identifies Modulators of Amyloid Precursor Protein Processing in Human Stem Cell Models of Alzheimer's Disease}}, journal = {Stem cell reports}, year = {2017}, doi = {10.1016/j.stemcr.2017.02.006}, pmid = {28285880}, url = {https://doi.org/10.1016/j.stemcr.2017.02.006} } @article{shah2018-29674739, author = {Shah, D. and Latif-Hernandez, A. and De Strooper, B. and Saito, T. and Saido, T. and Verhoye, M. and D'Hooge, R. and Van der Linden, A.}, title = {{Spatial reversal learning defect coincides with hypersynchronous telencephalic BOLD functional connectivity in APP NL-F/NL-F knock-in mice}}, journal = {Scientific reports}, year = {2018}, doi = {10.1038/s41598-018-24657-9}, pmid = {29674739}, url = {https://doi.org/10.1038/s41598-018-24657-9} } @article{destrooper1999-10206645, author = {De Strooper, B. and Annaert, W. and Cupers, P. and Saftig, P. and Craessaerts, K. and Mumm, J. S. and Schroeter, E. H. and Schrijvers, V. and others}, title = {{A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain}}, journal = {Nature}, year = {1999}, doi = {10.1038/19083}, pmid = {10206645}, url = {https://doi.org/10.1038/19083} } @article{destrooper1998-9450754, author = {De Strooper, B. and Saftig, P. and Craessaerts, K. and Vanderstichele, H. and Guhde, G. and Annaert, W. and Von Figura, K. and Van Leuven, F.}, title = {{Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein}}, journal = {Nature}, year = {1998}, doi = {10.1038/34910}, pmid = {9450754}, url = {https://doi.org/10.1038/34910} } @article{sasaguri2017-28768718, author = {Sasaguri, H. and Nilsson, P. and Hashimoto, S. and Nagata, K. and Saito, T. and De Strooper, B. and Hardy, J. and Vassar, R. and others}, title = {{APP mouse models for Alzheimer's disease preclinical studies}}, journal = {The EMBO journal}, year = {2017}, doi = {10.15252/embj.201797397}, pmid = {28768718}, url = {https://doi.org/10.15252/embj.201797397} } @article{arranz2019-30795987, author = {Arranz, A. M. and De Strooper, B.}, title = {{The role of astroglia in Alzheimer's disease: pathophysiology and clinical implications}}, journal = {The Lancet. Neurology}, year = {2019}, doi = {10.1016/s1474-4422(18)30490-3}, pmid = {30795987}, url = {https://doi.org/10.1016/s1474-4422(18)30490-3} } @article{hampel2021-32223911, author = {Hampel, H. and Vassar, R. and De Strooper, B. and Hardy, J. and Willem, M. and Singh, N. and Zhou, J. and Yan, R. and others}, title = {{The β-Secretase BACE1 in Alzheimer's Disease}}, journal = {Biological psychiatry}, year = {2021}, doi = {10.1016/j.biopsych.2020.02.001}, pmid = {32223911}, url = {https://doi.org/10.1016/j.biopsych.2020.02.001} } @article{destrooper2003-12691659, author = {De Strooper, B.}, title = {{Aph-1, Pen-2, and Nicastrin with Presenilin generate an active gamma-Secretase complex}}, journal = {Neuron}, year = {2003}, doi = {10.1016/s0896-6273(03)00205-8}, pmid = {12691659}, url = {https://doi.org/10.1016/s0896-6273(03)00205-8} } @article{karran2011-21852788, author = {Karran, E. and Mercken, M. and De Strooper, B.}, title = {{The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics}}, journal = {Nature reviews. Drug discovery}, year = {2011}, doi = {10.1038/nrd3505}, pmid = {21852788}, url = {https://doi.org/10.1038/nrd3505} }