% alzhub.org library filter % Source: https://alzhub.org/research?author=Bu+G % 26 entries, in the order the page lists them. Built from alzhub.org's own records. % 0 entries have no readable author in the source record and carry no author field. @article{shinohara2020-685d61d2, author = {Shinohara, M. and Kanekiyo, T. and Tachibana, M. and Kurti, A. and Fu, Y. and Zhao, J. and Han, X. and Sullivan, P. M. and Rebeck, G. W. and Fryer, J. D. and Heckman, M. G. and Bu, G.}, title = {{APOE2 is associated with longevity independent of Alzheimer's disease}}, journal = {eLife}, year = {2020} } @article{martens2022-35298921, author = {Martens, Y. A. and Zhao, N. and Liu, C. C. and Kanekiyo, T. and Yang, A. J. and Goate, A. M. and Holtzman, D. M. and Bu, G.}, title = {{ApoE Cascade Hypothesis in the pathogenesis of Alzheimer's disease and related dementias}}, journal = {Neuron}, year = {2022}, doi = {10.1016/j.neuron.2022.03.004}, pmid = {35298921}, url = {https://doi.org/10.1016/j.neuron.2022.03.004} } @article{liu2013-23296339, author = {Liu, C. C. and Kanekiyo, T. and Xu, H. and Bu, G.}, title = {{Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy}}, journal = {Nature reviews. Neurology}, year = {2013}, doi = {10.1038/nrneurol.2012.263}, pmid = {23296339}, url = {https://doi.org/10.1038/nrneurol.2012.263} } @article{inoue2023-37434208, author = {Inoue, Y. and Shue, F. and Bu, G. and Kanekiyo, T.}, title = {{Pathophysiology and probable etiology of cerebral small vessel disease in vascular dementia and Alzheimer's disease}}, journal = {Molecular neurodegeneration}, year = {2023}, doi = {10.1186/s13024-023-00640-5}, pmid = {37434208}, url = {https://doi.org/10.1186/s13024-023-00640-5} } @article{meneses2021-34930382, author = {Meneses, A. and Koga, S. and O'Leary, J. and Dickson, D. W. and Bu, G. and Zhao, N.}, title = {{TDP-43 Pathology in Alzheimer's Disease}}, journal = {Molecular neurodegeneration}, year = {2021}, doi = {10.1186/s13024-021-00503-x}, pmid = {34930382}, url = {https://doi.org/10.1186/s13024-021-00503-x} } @article{raulin2022-36348357, author = {Raulin, A. C. and Doss, S. V. and Trottier, Z. A. and Ikezu, T. C. and Bu, G. and Liu, C. C.}, title = {{ApoE in Alzheimer's disease: pathophysiology and therapeutic strategies}}, journal = {Molecular neurodegeneration}, year = {2022}, doi = {10.1186/s13024-022-00574-4}, pmid = {36348357}, url = {https://doi.org/10.1186/s13024-022-00574-4} } @article{yamazaki2019-31367008, author = {Yamazaki, Y. and Zhao, N. and Caulfield, T. R. and Liu, C. C. and Bu, G.}, title = {{Apolipoprotein E and Alzheimer disease: pathobiology and targeting strategies}}, journal = {Nature reviews. Neurology}, year = {2019}, doi = {10.1038/s41582-019-0228-7}, pmid = {31367008}, url = {https://doi.org/10.1038/s41582-019-0228-7} } @article{holtzman2012-22393530, author = {Holtzman, D. M. and Herz, J. and Bu, G.}, title = {{Apolipoprotein E and apolipoprotein E receptors: normal biology and roles in Alzheimer disease}}, journal = {Cold Spring Harbor perspectives in medicine}, year = {2012}, doi = {10.1101/cshperspect.a006312}, pmid = {22393530}, url = {https://doi.org/10.1101/cshperspect.a006312} } @article{zhang2025-40247363, author = {Zhang, L. and Xiang, X. and Li, Y. and Bu, G. and Chen, X. F.}, title = {{TREM2 and sTREM2 in Alzheimer's disease: from mechanisms to therapies}}, journal = {Molecular neurodegeneration}, year = {2025}, doi = {10.1186/s13024-025-00834-z}, pmid = {40247363}, url = {https://doi.org/10.1186/s13024-025-00834-z} } @article{painter2015-26337043, author = {Painter, M. M. and Atagi, Y. and Liu, C. C. and Rademakers, R. and Xu, H. and Fryer, J. D. and Bu, G.}, title = {{TREM2 in CNS homeostasis and neurodegenerative disease}}, journal = {Molecular neurodegeneration}, year = {2015}, doi = {10.1186/s13024-015-0040-9}, pmid = {26337043}, url = {https://doi.org/10.1186/s13024-015-0040-9} } @article{kanekiyo2014-24904407, author = {Kanekiyo, T. and Bu, G.}, title = {{The low-density lipoprotein receptor-related protein 1 and amyloid-β clearance in Alzheimer's disease}}, journal = {Frontiers in aging neuroscience}, year = {2014}, doi = {10.3389/fnagi.2014.00093}, pmid = {24904407}, url = {https://doi.org/10.3389/fnagi.2014.00093} } @article{holtzman1995-7568158, author = {Holtzman, D. M. and Pitas, R. E. and Kilbridge, J. and Nathan, B. and Mahley, R. W. and Bu, G. and Schwartz, A. L.}, title = {{Low density lipoprotein receptor-related protein mediates apolipoprotein E-dependent neurite outgrowth in a central nervous system-derived neuronal cell line}}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, year = {1995}, doi = {10.1073/pnas.92.21.9480}, pmid = {7568158}, url = {https://doi.org/10.1073/pnas.92.21.9480} } @article{nishitsuji2011-21471207, author = {Nishitsuji, K. and Hosono, T. and Nakamura, T. and Bu, G. and Michikawa, M.}, title = {{Apolipoprotein E regulates the integrity of tight junctions in an isoform-dependent manner in an in vitro blood-brain barrier model}}, journal = {The Journal of biological chemistry}, year = {2011}, doi = {10.1074/jbc.m111.225532}, pmid = {21471207}, url = {https://doi.org/10.1074/jbc.m111.225532} } @article{li2012-23132858, author = {Li, J. and Kanekiyo, T. and Shinohara, M. and Zhang, Y. and LaDu, M. J. and Xu, H. and Bu, G.}, title = {{Differential regulation of amyloid-β endocytic trafficking and lysosomal degradation by apolipoprotein E isoforms}}, journal = {The Journal of biological chemistry}, year = {2012}, doi = {10.1074/jbc.m112.420224}, pmid = {23132858}, url = {https://doi.org/10.1074/jbc.m112.420224} } @article{malik2015-26438529, author = {Malik, M. and Parikh, I. and Vasquez, J. B. and Smith, C. and Tai, L. and Bu, G. and LaDu, M. J. and Fardo, D. W. and others}, title = {{Genetics ignite focus on microglial inflammation in Alzheimer's disease}}, journal = {Molecular neurodegeneration}, year = {2015}, doi = {10.1186/s13024-015-0048-1}, pmid = {26438529}, url = {https://doi.org/10.1186/s13024-015-0048-1} } @article{kang2018-29040522, author = {Kang, S. S. and Kurti, A. and Baker, K. E. and Liu, C. C. and Colonna, M. and Ulrich, J. D. and Holtzman, D. M. and Bu, G. and others}, title = {{Behavioral and transcriptomic analysis of Trem2-null mice: not all knockout mice are created equal}}, journal = {Human molecular genetics}, year = {2018}, doi = {10.1093/hmg/ddx366}, pmid = {29040522}, url = {https://doi.org/10.1093/hmg/ddx366} } @article{lee2008-18276590, author = {Lee, J. and Retamal, C. and Cuitiño, L. and Caruano-Yzermans, A. and Shin, J. E. and van Kerkhof, P. and Marzolo, M. P. and Bu, G.}, title = {{Adaptor protein sorting nexin 17 regulates amyloid precursor protein trafficking and processing in the early endosomes}}, journal = {The Journal of biological chemistry}, year = {2008}, doi = {10.1074/jbc.m800642200}, pmid = {18276590}, url = {https://doi.org/10.1074/jbc.m800642200} } @article{zerbinatti2006-17012232, author = {Zerbinatti, C. V. and Wahrle, S. E. and Kim, H. and Cam, J. A. and Bales, K. and Paul, S. M. and Holtzman, D. M. and Bu, G.}, title = {{Apolipoprotein E and low density lipoprotein receptor-related protein facilitate intraneuronal Abeta42 accumulation in amyloid model mice}}, journal = {The Journal of biological chemistry}, year = {2006}, doi = {10.1074/jbc.m604436200}, pmid = {17012232}, url = {https://doi.org/10.1074/jbc.m604436200} } @article{yamazaki2020-31665905, author = {Yamazaki, Y. and Shinohara, M. and Yamazaki, A. and Ren, Y. and Asmann, Y. W. and Kanekiyo, T. and Bu, G.}, title = {{ApoE (Apolipoprotein E) in Brain Pericytes Regulates Endothelial Function in an Isoform-Dependent Manner by Modulating Basement Membrane Components}}, journal = {Arteriosclerosis, thrombosis, and vascular biology}, year = {2020}, doi = {10.1161/atvbaha.119.313169}, pmid = {31665905}, url = {https://doi.org/10.1161/atvbaha.119.313169} } @article{syrjanen2022-34569696, author = {Syrjanen, J. A. and Campbell, M. R. and Algeciras-Schimnich, A. and Vemuri, P. and Graff-Radford, J. and Machulda, M. M. and Bu, G. and Knopman, D. S. and others}, title = {{Associations of amyloid and neurodegeneration plasma biomarkers with comorbidities}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2022}, doi = {10.1002/alz.12466}, pmid = {34569696}, url = {https://doi.org/10.1002/alz.12466} } @article{hu2015-25871773, author = {Hu, J. and Liu, C. C. and Chen, X. F. and Zhang, Y. W. and Xu, H. and Bu, G.}, title = {{Opposing effects of viral mediated brain expression of apolipoprotein E2 (apoE2) and apoE4 on apoE lipidation and Aβ metabolism in apoE4-targeted replacement mice}}, journal = {Molecular neurodegeneration}, year = {2015}, doi = {10.1186/s13024-015-0001-3}, pmid = {25871773}, url = {https://doi.org/10.1186/s13024-015-0001-3} } @article{wang2014-25152012, author = {Wang, X. and Huang, T. and Bu, G. and Xu, H.}, title = {{Dysregulation of protein trafficking in neurodegeneration}}, journal = {Molecular neurodegeneration}, year = {2014}, doi = {10.1186/1750-1326-9-31}, pmid = {25152012}, url = {https://doi.org/10.1186/1750-1326-9-31} } @article{yamazaki2016-27328687, author = {Yamazaki, Y. and Painter, M. M. and Bu, G. and Kanekiyo, T.}, title = {{Apolipoprotein E as a Therapeutic Target in Alzheimer's Disease: A Review of Basic Research and Clinical Evidence}}, journal = {CNS drugs}, year = {2016}, doi = {10.1007/s40263-016-0361-4}, pmid = {27328687}, url = {https://doi.org/10.1007/s40263-016-0361-4} } @article{sun1998-9547235, author = {Sun, Y. and Wu, S. and Bu, G. and Onifade, M. K. and Patel, S. N. and LaDu, M. J. and Fagan, A. M. and Holtzman, D. M.}, title = {{Glial fibrillary acidic protein-apolipoprotein E (apoE) transgenic mice: astrocyte-specific expression and differing biological effects of astrocyte-secreted apoE3 and apoE4 lipoproteins}}, journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience}, year = {1998}, doi = {10.1523/jneurosci.18-09-03261.1998}, pmid = {9547235}, url = {https://doi.org/10.1523/jneurosci.18-09-03261.1998} } @article{verghese2013-23620513, author = {Verghese, P. B. and Castellano, J. M. and Garai, K. and Wang, Y. and Jiang, H. and Shah, A. and Bu, G. and Frieden, C. and others}, title = {{ApoE influences amyloid-β (Aβ) clearance despite minimal apoE/Aβ association in physiological conditions}}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, year = {2013}, doi = {10.1073/pnas.1220484110}, pmid = {23620513}, url = {https://doi.org/10.1073/pnas.1220484110} } @article{kanekiyo2014-24559670, author = {Kanekiyo, T. and Xu, H. and Bu, G.}, title = {{ApoE and Aβ in Alzheimer's disease: accidental encounters or partners?}}, journal = {Neuron}, year = {2014}, doi = {10.1016/j.neuron.2014.01.045}, pmid = {24559670}, url = {https://doi.org/10.1016/j.neuron.2014.01.045} }