% alzhub.org library filter % Source: https://alzhub.org/research?score_min=67&atag=soluble % 18 entries, in the order the page lists them. Built from alzhub.org's own records. % 0 entries have no readable author in the source record and carry no author field. @article{guerreiro2013-23150934, author = {Guerreiro, R. and Wojtas, A. and Bras, J. and Carrasquillo, M. and Rogaeva, E. and Majounie, E. and Cruchaga, C. and Sassi, C. and others}, title = {{TREM2 variants in Alzheimer's disease}}, journal = {The New England journal of medicine}, year = {2013}, doi = {10.1056/nejmoa1211851}, pmid = {23150934}, url = {https://doi.org/10.1056/nejmoa1211851} } @article{sims2017-28714976, author = {Sims, R. and van der Lee, S. J. and Naj, A. C. and Bellenguez, C. and Badarinarayan, N. and Jakobsdottir, J. and Kunkle, B. W. and Boland, A. and others}, title = {{Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease}}, journal = {Nature genetics}, year = {2017}, doi = {10.1038/ng.3916}, pmid = {28714976}, url = {https://doi.org/10.1038/ng.3916} } @article{lill2015-25936935, author = {Lill, C. M. and Rengmark, A. and Pihlstrøm, L. and Fogh, I. and Shatunov, A. and Sleiman, P. M. and Wang, L. S. and Liu, T. and others}, title = {{The role of TREM2 R47H as a risk factor for Alzheimer's disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and Parkinson's disease}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2015}, doi = {10.1016/j.jalz.2014.12.009}, pmid = {25936935}, url = {https://doi.org/10.1016/j.jalz.2014.12.009} } @article{jonsson2013-23150908, author = {Jonsson, T. and Stefansson, H. and Steinberg, S. and Jonsdottir, I. and Jonsson, P. V. and Snaedal, J. and Bjornsson, S. and Huttenlocher, J. and others}, title = {{Variant of TREM2 associated with the risk of Alzheimer's disease}}, journal = {The New England journal of medicine}, year = {2013}, doi = {10.1056/nejmoa1211103}, pmid = {23150908}, url = {https://doi.org/10.1056/nejmoa1211103} } @article{ruiz2014-24041969, author = {Ruiz, A. and Dols-Icardo, O. and Bullido, M. J. and Pastor, P. and Rodríguez-Rodríguez, E. and López de Munain, A. and de Pancorbo, M. M. and Pérez-Tur, J. and others}, title = {{Assessing the role of the TREM2 p.R47H variant as a risk factor for Alzheimer's disease and frontotemporal dementia}}, journal = {Neurobiology of aging}, year = {2014}, doi = {10.1016/j.neurobiolaging.2013.08.011}, pmid = {24041969}, url = {https://doi.org/10.1016/j.neurobiolaging.2013.08.011} } @article{mummery2026-41787076, author = {Mummery, C. J. and Mayorga, A. J. and Simmons, A. and Chow, T. W. and Burgess, B. and Nguyen, T. and Gao, J. and Budda, B. and Park, L. Q. and Gupta, R. and Li, C. and Shi, L. and others}, title = {{The TREM2 agonistic antibody AL002 in early Alzheimer's disease: a phase 2 randomized trial}}, journal = {Nature Medicine}, year = {2026}, doi = {10.1038/s41591-026-04273-1}, pmid = {41787076}, url = {https://doi.org/10.1038/s41591-026-04273-1} } @article{cicognola2025-39817469, author = {Cicognola, C. and Salvadó, G. and Smith, R. and Palmqvist, S. and Stomrud, E. and Betthauser, T. J. and Johnson, S. C. and Janelidze, S. and others}, title = {{APOE4 impact on soluble and insoluble tau pathology is mostly influenced by amyloid-β}}, journal = {Brain : a journal of neurology}, year = {2025}, doi = {10.1093/brain/awaf016}, pmid = {39817469}, url = {https://doi.org/10.1093/brain/awaf016} } @article{morenasrodriguez2022-35305339, author = {Morenas-Rodríguez, E. and Li, Y. and Nuscher, B. and Franzmeier, N. and Xiong, C. and Suárez-Calvet, M. and Fagan, A. M. and Schultz, S. and others}, title = {{Soluble TREM2 in CSF and its association with other biomarkers and cognition in autosomal-dominant Alzheimer's disease: a longitudinal observational study}}, journal = {The Lancet. Neurology}, year = {2022}, doi = {10.1016/s1474-4422(22)00027-8}, pmid = {35305339}, url = {https://doi.org/10.1016/s1474-4422(22)00027-8} } @article{parhizkar2019-30617257, author = {Parhizkar, S. and Arzberger, T. and Brendel, M. and Kleinberger, G. and Deussing, M. and Focke, C. and Nuscher, B. and Xiong, M. and others}, title = {{Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE}}, journal = {Nature neuroscience}, year = {2019}, doi = {10.1038/s41593-018-0296-9}, pmid = {30617257}, url = {https://doi.org/10.1038/s41593-018-0296-9} } @article{long2024-39444037, author = {Long, H. and Simmons, A. and Mayorga, A. and Burgess, B. and Nguyen, T. and Budda, B. and Rychkova, A. and Rhinn, H. and others}, title = {{Preclinical and first-in-human evaluation of AL002, a novel TREM2 agonistic antibody for Alzheimer's disease}}, journal = {Alzheimer's research \& therapy}, year = {2024}, doi = {10.1186/s13195-024-01599-1}, pmid = {39444037}, url = {https://doi.org/10.1186/s13195-024-01599-1} } @article{rikos2024-36408688, author = {Rikos, D. and Siokas, V. and Mentis, A. A. and Aloizou, A. M. and Liampas, I. and Tsouris, Z. and Peristeri, E. and Stamati, P. and others}, title = {{TREM2 R47H variant and risk for Alzheimer's disease: assessment in a Greek population and updated meta-analysis}}, journal = {The International journal of neuroscience}, year = {2024}, doi = {10.1080/00207454.2022.2150844}, pmid = {36408688}, url = {https://doi.org/10.1080/00207454.2022.2150844} } @article{piccio2016-26754641, author = {Piccio, L. and Deming, Y. and Del-Águila, J. L. and Ghezzi, L. and Holtzman, D. M. and Fagan, A. M. and Fenoglio, C. and Galimberti, D. and others}, title = {{Cerebrospinal fluid soluble TREM2 is higher in Alzheimer disease and associated with mutation status}}, journal = {Acta neuropathologica}, year = {2016}, doi = {10.1007/s00401-016-1533-5}, pmid = {26754641}, url = {https://doi.org/10.1007/s00401-016-1533-5} } @article{suarezcalvet2019-30630532, author = {Suárez-Calvet, M. and Morenas-Rodríguez, E. and Kleinberger, G. and Schlepckow, K. and MÁ, Araque Caballero and Franzmeier, N. and Capell, A. and Fellerer, K. and others}, title = {{Early increase of CSF sTREM2 in Alzheimer's disease is associated with tau related-neurodegeneration but not with amyloid-β pathology}}, journal = {Molecular neurodegeneration}, year = {2019}, doi = {10.1186/s13024-018-0301-5}, pmid = {30630532}, url = {https://doi.org/10.1186/s13024-018-0301-5} } @article{benitez2014-24439484, author = {Benitez, B. A. and Jin, S. C. and Guerreiro, R. and Graham, R. and Lord, J. and Harold, D. and Sims, R. and Lambert, J. C. and others}, title = {{Missense variant in TREML2 protects against Alzheimer's disease}}, journal = {Neurobiology of aging}, year = {2014}, doi = {10.1016/j.neurobiolaging.2013.12.010}, pmid = {24439484}, url = {https://doi.org/10.1016/j.neurobiolaging.2013.12.010} } @article{carrasquillo2017-27939925, author = {Carrasquillo, M. M. and Allen, M. and Burgess, J. D. and Wang, X. and Strickland, S. L. and Aryal, S. and Siuda, J. and Kachadoorian, M. L. and others}, title = {{A candidate regulatory variant at the TREM gene cluster associates with decreased Alzheimer's disease risk and increased TREML1 and TREM2 brain gene expression}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2017}, doi = {10.1016/j.jalz.2016.10.005}, pmid = {27939925}, url = {https://doi.org/10.1016/j.jalz.2016.10.005} } @article{jin2015-25886450, author = {Jin, S. C. and Carrasquillo, M. M. and Benitez, B. A. and Skorupa, T. and Carrell, D. and Patel, D. and Lincoln, S. and Krishnan, S. and others}, title = {{TREM2 is associated with increased risk for Alzheimer's disease in African Americans}}, journal = {Molecular neurodegeneration}, year = {2015}, doi = {10.1186/s13024-015-0016-9}, pmid = {25886450}, url = {https://doi.org/10.1186/s13024-015-0016-9} } @article{kleineidam2020-32166339, author = {Kleineidam, L. and Chouraki, V. and Próchnicki, T. and van der Lee, S. J. and Madrid-Márquez, L. and Wagner-Thelen, H. and Karaca, I. and Weinhold, L. and others}, title = {{PLCG2 protective variant p.P522R modulates tau pathology and disease progression in patients with mild cognitive impairment}}, journal = {Acta neuropathologica}, year = {2020}, doi = {10.1007/s00401-020-02138-6}, pmid = {32166339}, url = {https://doi.org/10.1007/s00401-020-02138-6} } @article{liu2016-26365049, author = {Liu, G. and Liu, Y. and Jiang, Q. and Jiang, Y. and Feng, R. and Zhang, L. and Chen, Z. and Li, K. and others}, title = {{Convergent Genetic and Expression Datasets Highlight TREM2 in Parkinson's Disease Susceptibility}}, journal = {Molecular neurobiology}, year = {2016}, doi = {10.1007/s12035-015-9416-7}, pmid = {26365049}, url = {https://doi.org/10.1007/s12035-015-9416-7} }