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% Source: https://alzhub.org/research?institution=I45129253&atag=soluble
% 27 entries, in the order the page lists them. Built from alzhub.org's own records.
% 0 entries have no readable author in the source record and carry no author field.

@article{guerreiro2013-23150934,
  author  = {Guerreiro, R. and Wojtas, A. and Bras, J. and Carrasquillo, M. and Rogaeva, E. and Majounie, E. and Cruchaga, C. and Sassi, C. and others},
  title   = {{TREM2 variants in Alzheimer's disease}},
  journal = {The New England journal of medicine},
  year    = {2013},
  doi     = {10.1056/nejmoa1211851},
  pmid    = {23150934},
  url     = {https://doi.org/10.1056/nejmoa1211851}
}

@article{mummery2026-41787076,
  author  = {Mummery, C. J. and Mayorga, A. J. and Simmons, A. and Chow, T. W. and Burgess, B. and Nguyen, T. and Gao, J. and Budda, B. and Park, L. Q. and Gupta, R. and Li, C. and Shi, L. and others},
  title   = {{The TREM2 agonistic antibody AL002 in early Alzheimer's disease: a phase 2 randomized trial}},
  journal = {Nature Medicine},
  year    = {2026},
  doi     = {10.1038/s41591-026-04273-1},
  pmid    = {41787076},
  url     = {https://doi.org/10.1038/s41591-026-04273-1}
}

@article{morenasrodriguez2022-35305339,
  author  = {Morenas-Rodríguez, E. and Li, Y. and Nuscher, B. and Franzmeier, N. and Xiong, C. and Suárez-Calvet, M. and Fagan, A. M. and Schultz, S. and others},
  title   = {{Soluble TREM2 in CSF and its association with other biomarkers and cognition in autosomal-dominant Alzheimer's disease: a longitudinal observational study}},
  journal = {The Lancet. Neurology},
  year    = {2022},
  doi     = {10.1016/s1474-4422(22)00027-8},
  pmid    = {35305339},
  url     = {https://doi.org/10.1016/s1474-4422(22)00027-8}
}

@article{benitez2014-24439484,
  author  = {Benitez, B. A. and Jin, S. C. and Guerreiro, R. and Graham, R. and Lord, J. and Harold, D. and Sims, R. and Lambert, J. C. and others},
  title   = {{Missense variant in TREML2 protects against Alzheimer's disease}},
  journal = {Neurobiology of aging},
  year    = {2014},
  doi     = {10.1016/j.neurobiolaging.2013.12.010},
  pmid    = {24439484},
  url     = {https://doi.org/10.1016/j.neurobiolaging.2013.12.010}
}

@article{suarezcalvet2016-26941262,
  author  = {Suárez-Calvet, M. and Kleinberger, G. and MÁ, Araque Caballero and Brendel, M. and Rominger, A. and Alcolea, D. and Fortea, J. and Lleó, A. and others},
  title   = {{sTREM2 cerebrospinal fluid levels are a potential biomarker for microglia activity in early-stage Alzheimer's disease and associate with neuronal injury markers}},
  journal = {EMBO molecular medicine},
  year    = {2016},
  doi     = {10.15252/emmm.201506123},
  pmid    = {26941262},
  url     = {https://doi.org/10.15252/emmm.201506123}
}

@article{heslegrave2016-26754172,
  author  = {Heslegrave, A. and Heywood, W. and Paterson, R. and Magdalinou, N. and Svensson, J. and Johansson, P. and Öhrfelt, A. and Blennow, K. and others},
  title   = {{Increased cerebrospinal fluid soluble TREM2 concentration in Alzheimer's disease}},
  journal = {Molecular neurodegeneration},
  year    = {2016},
  doi     = {10.1186/s13024-016-0071-x},
  pmid    = {26754172},
  url     = {https://doi.org/10.1186/s13024-016-0071-x}
}

@article{kleinberger2014-24990881,
  author  = {Kleinberger, G. and Yamanishi, Y. and Suárez-Calvet, M. and Czirr, E. and Lohmann, E. and Cuyvers, E. and Struyfs, H. and Pettkus, N. and others},
  title   = {{TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis}},
  journal = {Science translational medicine},
  year    = {2014},
  doi     = {10.1126/scitranslmed.3009093},
  pmid    = {24990881},
  url     = {https://doi.org/10.1126/scitranslmed.3009093}
}

@article{woollacott2018-30111356,
  author  = {Woollacott, I. O. C. and Nicholas, J. M. and Heslegrave, A. and Heller, C. and Foiani, M. S. and Dick, K. M. and Russell, L. L. and Paterson, R. W. and others},
  title   = {{Cerebrospinal fluid soluble TREM2 levels in frontotemporal dementia differ by genetic and pathological subgroup}},
  journal = {Alzheimer's research \& therapy},
  year    = {2018},
  doi     = {10.1186/s13195-018-0405-8},
  pmid    = {30111356},
  url     = {https://doi.org/10.1186/s13195-018-0405-8}
}

@article{slattery2014-25160042,
  author  = {Slattery, C. F. and Beck, J. A. and Harper, L. and Adamson, G. and Abdi, Z. and Uphill, J. and Campbell, T. and Druyeh, R. and others},
  title   = {{R47H TREM2 variant increases risk of typical early-onset Alzheimer's disease but not of prion or frontotemporal dementia}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2014},
  doi     = {10.1016/j.jalz.2014.05.1751},
  pmid    = {25160042},
  url     = {https://doi.org/10.1016/j.jalz.2014.05.1751}
}

@article{ruedacarrasco2023-37575021,
  author  = {Rueda-Carrasco, J. and Sokolova, D. and Lee, S. E. and Childs, T. and Jurčáková, N. and Crowley, G. and De Schepper, S. and Ge, J. Z. and others},
  title   = {{Microglia-synapse engulfment via PtdSer-TREM2 ameliorates neuronal hyperactivity in Alzheimer's disease models}},
  journal = {The EMBO journal},
  year    = {2023},
  doi     = {10.15252/embj.2022113246},
  pmid    = {37575021},
  url     = {https://doi.org/10.15252/embj.2022113246}
}

@article{deming2019-31413141,
  author  = {Deming, Y. and Filipello, F. and Cignarella, F. and Cantoni, C. and Hsu, S. and Mikesell, R. and Li, Z. and Del-Aguila, J. L. and others},
  title   = {{The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer's disease risk}},
  journal = {Science translational medicine},
  year    = {2019},
  doi     = {10.1126/scitranslmed.aau2291},
  pmid    = {31413141},
  url     = {https://doi.org/10.1126/scitranslmed.aau2291}
}

@article{schlepckow2023-37863592,
  author  = {Schlepckow, K. and Morenas-Rodríguez, E. and Hong, S. and Haass, C.},
  title   = {{Stimulation of TREM2 with agonistic antibodies-an emerging therapeutic option for Alzheimer's disease}},
  journal = {The Lancet. Neurology},
  year    = {2023},
  doi     = {10.1016/s1474-4422(23)00247-8},
  pmid    = {37863592},
  url     = {https://doi.org/10.1016/s1474-4422(23)00247-8}
}

@article{tagliatti2024-38159572,
  author  = {Tagliatti, E. and Desiato, G. and Mancinelli, S. and Bizzotto, M. and Gagliani, M. C. and Faggiani, E. and Hernández-Soto, R. and Cugurra, A. and others},
  title   = {{Trem2 expression in microglia is required to maintain normal neuronal bioenergetics during development}},
  journal = {Immunity},
  year    = {2024},
  doi     = {10.1016/j.immuni.2023.12.002},
  pmid    = {38159572},
  url     = {https://doi.org/10.1016/j.immuni.2023.12.002}
}

@article{carmona2018-30033062,
  author  = {Carmona, S. and Zahs, K. and Wu, E. and Dakin, K. and Bras, J. and Guerreiro, R.},
  title   = {{The role of TREM2 in Alzheimer's disease and other neurodegenerative disorders}},
  journal = {The Lancet. Neurology},
  year    = {2018},
  doi     = {10.1016/s1474-4422(18)30232-1},
  pmid    = {30033062},
  url     = {https://doi.org/10.1016/s1474-4422(18)30232-1}
}

@article{sayed2021-34851693,
  author  = {Sayed, F. A. and Kodama, L. and Fan, L. and Carling, G. K. and Udeochu, J. C. and Le, D. and Li, Q. and Zhou, L. and others},
  title   = {{AD-linked R47H-TREM2 mutation induces disease-enhancing microglial states via AKT hyperactivation}},
  journal = {Science translational medicine},
  year    = {2021},
  doi     = {10.1126/scitranslmed.abe3947},
  pmid    = {34851693},
  url     = {https://doi.org/10.1126/scitranslmed.abe3947}
}

@article{xiang2018-30185230,
  author  = {Xiang, X. and Piers, T. M. and Wefers, B. and Zhu, K. and Mallach, A. and Brunner, B. and Kleinberger, G. and Song, W. and others},
  title   = {{The Trem2 R47H Alzheimer's risk variant impairs splicing and reduces Trem2 mRNA and protein in mice but not in humans}},
  journal = {Molecular neurodegeneration},
  year    = {2018},
  doi     = {10.1186/s13024-018-0280-6},
  pmid    = {30185230},
  url     = {https://doi.org/10.1186/s13024-018-0280-6}
}

@article{liu2020-32959884,
  author  = {Liu, W. and Taso, O. and Wang, R. and Bayram, S. and Graham, A. C. and Garcia-Reitboeck, P. and Mallach, A. and Andrews, W. D. and others},
  title   = {{Trem2 promotes anti-inflammatory responses in microglia and is suppressed under pro-inflammatory conditions}},
  journal = {Human molecular genetics},
  year    = {2020},
  doi     = {10.1093/hmg/ddaa209},
  pmid    = {32959884},
  url     = {https://doi.org/10.1093/hmg/ddaa209}
}

@article{forabosco2013-23855984,
  author  = {Forabosco, P. and Ramasamy, A. and Trabzuni, D. and Walker, R. and Smith, C. and Bras, J. and Levine, A. P. and Hardy, J. and others},
  title   = {{Insights into TREM2 biology by network analysis of human brain gene expression data}},
  journal = {Neurobiology of aging},
  year    = {2013},
  doi     = {10.1016/j.neurobiolaging.2013.05.001},
  pmid    = {23855984},
  url     = {https://doi.org/10.1016/j.neurobiolaging.2013.05.001}
}

@article{gisslen2019-30568991,
  author  = {Gisslén, M. and Heslegrave, A. and Veleva, E. and Yilmaz, A. and Andersson, L. M. and Hagberg, L. and Spudich, S. and Fuchs, D. and others},
  title   = {{CSF concentrations of soluble TREM2 as a marker of microglial activation in HIV-1 infection}},
  journal = {Neurology(R) neuroimmunology \& neuroinflammation},
  year    = {2019},
  doi     = {10.1212/nxi.0000000000000512},
  pmid    = {30568991},
  url     = {https://doi.org/10.1212/nxi.0000000000000512}
}

@article{guerreiro2013-23870839,
  author  = {Guerreiro, R. and Bilgic, B. and Guven, G. and Brás, J. and Rohrer, J. and Lohmann, E. and Hanagasi, H. and Gurvit, H. and others},
  title   = {{Novel compound heterozygous mutation in TREM2 found in a Turkish frontotemporal dementia-like family}},
  journal = {Neurobiology of aging},
  year    = {2013},
  doi     = {10.1016/j.neurobiolaging.2013.06.005},
  pmid    = {23870839},
  url     = {https://doi.org/10.1016/j.neurobiolaging.2013.06.005}
}

@article{ohrfelt2016-26754805,
  author  = {Öhrfelt, A. and Axelsson, M. and Malmeström, C. and Novakova, L. and Heslegrave, A. and Blennow, K. and Lycke, J. and Zetterberg, H.},
  title   = {{Soluble TREM-2 in cerebrospinal fluid from patients with multiple sclerosis treated with natalizumab or mitoxantrone}},
  journal = {Multiple sclerosis (Houndmills, Basingstoke, England)},
  year    = {2016},
  doi     = {10.1177/1352458515624558},
  pmid    = {26754805},
  url     = {https://doi.org/10.1177/1352458515624558}
}

@article{matarin2015-25620700,
  author  = {Matarin, M. and Salih, D. A. and Yasvoina, M. and Cummings, D. M. and Guelfi, S. and Liu, W. and Nahaboo Solim, M. A. and Moens, T. G. and others},
  title   = {{A genome-wide gene-expression analysis and database in transgenic mice during development of amyloid or tau pathology}},
  journal = {Cell reports},
  year    = {2015},
  doi     = {10.1016/j.celrep.2014.12.041},
  pmid    = {25620700},
  url     = {https://doi.org/10.1016/j.celrep.2014.12.041}
}

@article{garciareitboeck2018-30157425,
  author  = {Garcia-Reitboeck, P. and Phillips, A. and Piers, T. M. and Villegas-Llerena, C. and Butler, M. and Mallach, A. and Rodrigues, C. and Arber, C. E. and others},
  title   = {{Human Induced Pluripotent Stem Cell-Derived Microglia-Like Cells Harboring TREM2 Missense Mutations Show Specific Deficits in Phagocytosis}},
  journal = {Cell reports},
  year    = {2018},
  doi     = {10.1016/j.celrep.2018.07.094},
  pmid    = {30157425},
  url     = {https://doi.org/10.1016/j.celrep.2018.07.094}
}

@article{piers2020-31907987,
  author  = {Piers, T. M. and Cosker, K. and Mallach, A. and Johnson, G. T. and Guerreiro, R. and Hardy, J. and Pocock, J. M.},
  title   = {{A locked immunometabolic switch underlies TREM2 R47H loss of function in human iPSC-derived microglia}},
  journal = {FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  year    = {2020},
  doi     = {10.1096/fj.201902447r},
  pmid    = {31907987},
  url     = {https://doi.org/10.1096/fj.201902447r}
}

@article{brownjohn2018-29606617,
  author  = {Brownjohn, P. W. and Smith, J. and Solanki, R. and Lohmann, E. and Houlden, H. and Hardy, J. and Dietmann, S. and Livesey, F. J.},
  title   = {{Functional Studies of Missense TREM2 Mutations in Human Stem Cell-Derived Microglia}},
  journal = {Stem cell reports},
  year    = {2018},
  doi     = {10.1016/j.stemcr.2018.03.003},
  pmid    = {29606617},
  url     = {https://doi.org/10.1016/j.stemcr.2018.03.003}
}

@article{wood2022-36417868,
  author  = {Wood, J. I. and Wong, E. and Joghee, R. and Balbaa, A. and Vitanova, K. S. and Stringer, K. M. and Vanshoiack, A. and Phelan, S. J. and others},
  title   = {{Plaque contact and unimpaired Trem2 is required for the microglial response to amyloid pathology}},
  journal = {Cell reports},
  year    = {2022},
  doi     = {10.1016/j.celrep.2022.111686},
  pmid    = {36417868},
  url     = {https://doi.org/10.1016/j.celrep.2022.111686}
}

@article{deming2018-3f7a9435,
  author  = {Deming, Y. and Filipello, F. and Cignarella, F. and Cantoni, C. and Hsu, S. and Mikesell, R. and Li, Z. and Del-Aguila, J. L. and others},
  title   = {{The MS4A gene cluster is a key regulator of soluble TREM2 and Alzheimer disease risk}},
  journal = {Science translational medicine},
  year    = {2018},
  doi     = {10.1101/352179},
  url     = {https://doi.org/10.1101/352179}
}