% alzhub.org library filter % Source: https://alzhub.org/research?institution=I78577930&atag=precursor % 76 entries, in the order the page lists them. Built from alzhub.org's own records. % 0 entries have no readable author in the source record and carry no author field. @article{kunkle2019-30820047, author = {Kunkle, B. W. and Grenier-Boley, B. and Sims, R. and Bis, J. C. and Damotte, V. and Naj, A. C. and Boland, A. and Vronskaya, M. and others}, title = {{Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing}}, journal = {Nature genetics}, year = {2019}, doi = {10.1038/s41588-019-0358-2}, pmid = {30820047}, url = {https://doi.org/10.1038/s41588-019-0358-2} } @article{naj2011-21460841, author = {Naj, A. C. and Jun, G. and Beecham, G. W. and Wang, L. S. and Vardarajan, B. N. and Buros, J. and Gallins, P. J. and Buxbaum, J. D. and others}, title = {{Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease}}, journal = {Nature genetics}, year = {2011}, doi = {10.1038/ng.801}, pmid = {21460841}, url = {https://doi.org/10.1038/ng.801} } @article{reitz2013-23571587, author = {Reitz, C. and Jun, G. and Naj, A. and Rajbhandary, R. and Vardarajan, B. N. and Wang, L. S. and Valladares, O. and Lin, C. F. and others}, title = {{Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans}}, journal = {JAMA}, year = {2013}, doi = {10.1001/jama.2013.2973}, pmid = {23571587}, url = {https://doi.org/10.1001/jama.2013.2973} } @article{kunkle2021-33074286, author = {Kunkle, B. W. and Schmidt, M. and Klein, H. U. and Naj, A. C. and Hamilton-Nelson, K. L. and Larson, E. B. and Evans, D. A. and De Jager, P. L. and others}, title = {{Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis}}, journal = {JAMA neurology}, year = {2021}, doi = {10.1001/jamaneurol.2020.3536}, pmid = {33074286}, url = {https://doi.org/10.1001/jamaneurol.2020.3536} } @article{rajabli2025-40676597, author = {Rajabli, F. and Benchek, P. and Tosto, G. and Kushch, N. and Sha, J. and Bazemore, K. and Zhu, C. and Lee, W. P. and others}, title = {{Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies known and novel cross-population and ancestry-specific associations as novel risk loci for Alzheimer's disease}}, journal = {Genome biology}, year = {2025}, doi = {10.1186/s13059-025-03564-z}, pmid = {40676597}, url = {https://doi.org/10.1186/s13059-025-03564-z} } @article{bhattarai2024-38598053, author = {Bhattarai, P. and Gunasekaran, T. I. and Belloy, M. E. and Reyes-Dumeyer, D. and Jülich, D. and Tayran, H. and Yilmaz, E. and Flaherty, D. and Turgutalp, B. and Sukumar, G. and Alba, C. and McGrath, E. M. and others}, title = {{Rare genetic variation in fibronectin 1 (FN1) protects against APOEε4 in Alzheimer's disease}}, journal = {Acta Neuropathologica}, year = {2024}, doi = {10.1007/s00401-024-02721-1}, pmid = {38598053}, url = {https://doi.org/10.1007/s00401-024-02721-1} } @article{naj2014-25199842, author = {Naj, A. C. and Jun, G. and Reitz, C. and Kunkle, B. W. and Perry, W. and Park, Y. S. and Beecham, G. W. and Rajbhandary, R. A. and others}, title = {{Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study}}, journal = {JAMA neurology}, year = {2014}, doi = {10.1001/jamaneurol.2014.1491}, pmid = {25199842}, url = {https://doi.org/10.1001/jamaneurol.2014.1491} } @article{nelson2014-24770881, author = {Nelson, P. T. and Estus, S. and Abner, E. L. and Parikh, I. and Malik, M. and Neltner, J. H. and Ighodaro, E. and Wang, W. X. and others}, title = {{ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology}}, journal = {Acta neuropathologica}, year = {2014}, doi = {10.1007/s00401-014-1282-2}, pmid = {24770881}, url = {https://doi.org/10.1007/s00401-014-1282-2} } @article{raghavan2020-32568366, author = {Raghavan, N. S. and Dumitrescu, L. and Mormino, E. and Mahoney, E. R. and Lee, A. J. and Gao, Y. and Bilgel, M. and Goldstein, D. and others}, title = {{Association Between Common Variants in RBFOX1, an RNA-Binding Protein, and Brain Amyloidosis in Early and Preclinical Alzheimer Disease}}, journal = {JAMA neurology}, year = {2020}, doi = {10.1001/jamaneurol.2020.1760}, pmid = {32568366}, url = {https://doi.org/10.1001/jamaneurol.2020.1760} } @article{tang1998-9508150, author = {Tang, M. X. and Stern, Y. and Marder, K. and Bell, K. and Gurland, B. and Lantigua, R. and Andrews, H. and Feng, L. and others}, title = {{The APOE-epsilon4 allele and the risk of Alzheimer disease among African Americans, whites, and Hispanics}}, journal = {JAMA}, year = {1998}, doi = {10.1001/jama.279.10.751}, pmid = {9508150}, url = {https://doi.org/10.1001/jama.279.10.751} } @article{dube2019-31591557, author = {Dube, U. and Del-Aguila, J. L. and Li, Z. and Budde, J. P. and Jiang, S. and Hsu, S. and Ibanez, L. and Fernandez, M. V. and others}, title = {{An atlas of cortical circular RNA expression in Alzheimer disease brains demonstrates clinical and pathological associations}}, journal = {Nature neuroscience}, year = {2019}, doi = {10.1038/s41593-019-0501-5}, pmid = {31591557}, url = {https://doi.org/10.1038/s41593-019-0501-5} } @article{miyashita2013-23565137, author = {Miyashita, A. and Koike, A. and Jun, G. and Wang, L. S. and Takahashi, S. and Matsubara, E. and Kawarabayashi, T. and Shoji, M. and others}, title = {{SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians}}, journal = {PloS one}, year = {2013}, doi = {10.1371/journal.pone.0058618}, pmid = {23565137}, url = {https://doi.org/10.1371/journal.pone.0058618} } @article{bettens2012-22248099, author = {Bettens, K. and Brouwers, N. and Engelborghs, S. and Lambert, J. C. and Rogaeva, E. and Vandenberghe, R. and Le Bastard, N. and Pasquier, F. and others}, title = {{Both common variations and rare non-synonymous substitutions and small insertion/deletions in CLU are associated with increased Alzheimer risk}}, journal = {Molecular neurodegeneration}, year = {2012}, doi = {10.1186/1750-1326-7-3}, pmid = {22248099}, url = {https://doi.org/10.1186/1750-1326-7-3} } @article{holstege2022-36411364, author = {Holstege, H. and Hulsman, M. and Charbonnier, C. and Grenier-Boley, B. and Quenez, O. and Grozeva, D. and van Rooij, J. G. J. and Sims, R. and others}, title = {{Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer's disease}}, journal = {Nature genetics}, year = {2022}, doi = {10.1038/s41588-022-01208-7}, pmid = {36411364}, url = {https://doi.org/10.1038/s41588-022-01208-7} } @article{leguen2022-35639372, author = {Le Guen, Y. and Belloy, M. E. and Grenier-Boley, B. and de Rojas, I. and Castillo-Morales, A. and Jansen, I. and Nicolas, A. and Bellenguez, C. and others}, title = {{Association of Rare APOE Missense Variants V236E and R251G With Risk of Alzheimer Disease}}, journal = {JAMA neurology}, year = {2022}, doi = {10.1001/jamaneurol.2022.1166}, pmid = {35639372}, url = {https://doi.org/10.1001/jamaneurol.2022.1166} } @article{rabin2022-35759327, author = {Rabin, J. S. and Nichols, E. and La Joie, R. and Casaletto, K. B. and Palta, P. and Dams-O'Connor, K. and Kumar, R. G. and George, K. M. and others}, title = {{Cerebral amyloid angiopathy interacts with neuritic amyloid plaques to promote tau and cognitive decline}}, journal = {Brain : a journal of neurology}, year = {2022}, doi = {10.1093/brain/awac178}, pmid = {35759327}, url = {https://doi.org/10.1093/brain/awac178} } @article{reitz2011-21220680, author = {Reitz, C. and Cheng, R. and Rogaeva, E. and Lee, J. H. and Tokuhiro, S. and Zou, F. and Bettens, K. and Sleegers, K. and others}, title = {{Meta-analysis of the association between variants in SORL1 and Alzheimer disease}}, journal = {Archives of neurology}, year = {2011}, doi = {10.1001/archneurol.2010.346}, pmid = {21220680}, url = {https://doi.org/10.1001/archneurol.2010.346} } @article{ray2025-40096060, author = {Ray, Nicholas R. and Bradley, Joseph L. and Yılmaz, Elanur and Kızıl, Çağhan and Kurup, Jiji Thulaseedhara and Martin, Eden R. and Klein, Hans‐Ulrich and Kunkle, Brian W. and others}, title = {{Local genetic covariance analysis with lipid traits identifies novel loci for early-onset Alzheimer’s Disease}}, journal = {PLoS Genetics}, year = {2025}, doi = {10.1371/journal.pgen.1011631}, pmid = {40096060}, url = {https://doi.org/10.1371/journal.pgen.1011631} } @article{barral2025-40219824, author = {Barral, S. and Yang, Z. and Phillips, N. and Barber, R. C. and Brickman, A. M. and Honig, L. S. and Cieza, B. and Reyes-Dumeyer, D. and Mayeux, R. and Rajabli, F. and others}, title = {{APOE and Alzheimer's disease and related dementias risk among 12,221 Hispanics/Latinos}}, journal = {Alzheimer's \& Dementia}, year = {2025}, doi = {10.1002/alz.70138}, pmid = {40219824}, url = {https://doi.org/10.1002/alz.70138} } @article{rajabli2018-30517106, author = {Rajabli, F. and Feliciano, B. E. and Celis, K. and Hamilton-Nelson, K. L. and Whitehead, P. L. and Adams, L. D. and Bussies, P. L. and Manrique, C. P. and others}, title = {{Ancestral origin of ApoE ε4 Alzheimer disease risk in Puerto Rican and African American populations}}, journal = {PLoS genetics}, year = {2018}, doi = {10.1371/journal.pgen.1007791}, pmid = {30517106}, url = {https://doi.org/10.1371/journal.pgen.1007791} } @article{allen2012-22722634, author = {Allen, M. and Zou, F. and Chai, H. S. and Younkin, C. S. and Crook, J. and Pankratz, V. S. and Carrasquillo, M. M. and Rowley, C. N. and others}, title = {{Novel late-onset Alzheimer disease loci variants associate with brain gene expression}}, journal = {Neurology}, year = {2012}, doi = {10.1212/wnl.0b013e3182605801}, pmid = {22722634}, url = {https://doi.org/10.1212/wnl.0b013e3182605801} } @article{jun2014-25043464, author = {Jun, G. and Asai, H. and Zeldich, E. and Drapeau, E. and Chen, C. and Chung, J. and Park, J. H. and Kim, S. and others}, title = {{PLXNA4 is associated with Alzheimer disease and modulates tau phosphorylation}}, journal = {Annals of neurology}, year = {2014}, doi = {10.1002/ana.24219}, pmid = {25043464}, url = {https://doi.org/10.1002/ana.24219} } @article{reiman2020-32015339, author = {Reiman, E. M. and Arboleda-Velasquez, J. F. and Quiroz, Y. T. and Huentelman, M. J. and Beach, T. G. and Caselli, R. J. and Chen, Y. and Su, Y. and others}, title = {{Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study}}, journal = {Nature communications}, year = {2020}, doi = {10.1038/s41467-019-14279-8}, pmid = {32015339}, url = {https://doi.org/10.1038/s41467-019-14279-8} } @article{mayeux1998-9468467, author = {Mayeux, R. and Saunders, A. M. and Shea, S. and Mirra, S. and Evans, D. and Roses, A. D. and Hyman, B. T. and Crain, B. and others}, title = {{Utility of the apolipoprotein E genotype in the diagnosis of Alzheimer's disease. Alzheimer's Disease Centers Consortium on Apolipoprotein E and Alzheimer's Disease}}, journal = {The New England journal of medicine}, year = {1998}, doi = {10.1056/nejm199802193380804}, pmid = {9468467}, url = {https://doi.org/10.1056/nejm199802193380804} } @article{rogaeva2007-17220890, author = {Rogaeva, E. and Meng, Y. and Lee, J. H. and Gu, Y. and Kawarai, T. and Zou, F. and Katayama, T. and Baldwin, C. T. and others}, title = {{The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease}}, journal = {Nature genetics}, year = {2007}, doi = {10.1038/ng1943}, pmid = {17220890}, url = {https://doi.org/10.1038/ng1943} } @article{bradley2025-40556318, author = {Bradley, J. and Pottier, C. and da Fonseca, E. L. and Kurup, J. T. and Western, D. and Wang, C. and Neupane, A. and Ray, N. R. and Jean-Francois, M. and Ali, M. and Timsina, J. and Bergmann, K. and others}, title = {{Novel early-onset Alzheimer-associated genes influence risk through dysregulation of glutamate, immune activation, and intracellular signaling pathways}}, journal = {Alzheimer's \& Dementia}, year = {2025}, doi = {10.1002/alz.70377}, pmid = {40556318}, url = {https://doi.org/10.1002/alz.70377} } @article{cosentino2008-18401023, author = {Cosentino, S. and Scarmeas, N. and Helzner, E. and Glymour, M. M. and Brandt, J. and Albert, M. and Blacker, D. and Stern, Y.}, title = {{APOE epsilon 4 allele predicts faster cognitive decline in mild Alzheimer disease}}, journal = {Neurology}, year = {2008}, doi = {10.1212/01.wnl.0000304038.37421.cc}, pmid = {18401023}, url = {https://doi.org/10.1212/01.wnl.0000304038.37421.cc} } @article{honig2006-16807921, author = {Honig, L. S. and Schupf, N. and Lee, J. H. and Tang, M. X. and Mayeux, R.}, title = {{Shorter telomeres are associated with mortality in those with APOE epsilon4 and dementia}}, journal = {Annals of neurology}, year = {2006}, doi = {10.1002/ana.20894}, pmid = {16807921}, url = {https://doi.org/10.1002/ana.20894} } @article{rajabli2023-36539198, author = {Rajabli, F. and Tosto, G. and Hamilton-Nelson, K. L. and Kunkle, B. W. and Vardarajan, B. N. and Naj, A. and Whitehead, P. G. and Gardner, O. K. and Bush, W. S. and Sariya, S. and Mayeux, R. P. and Farrer, L. A. and others}, title = {{Admixture mapping identifies novel Alzheimer's disease risk regions in African Americans}}, journal = {Alzheimer's \& Dementia}, year = {2023}, doi = {10.1002/alz.12865}, pmid = {36539198}, url = {https://doi.org/10.1002/alz.12865} } @article{cruchaga2012-22312439, author = {Cruchaga, C. and Haller, G. and Chakraverty, S. and Mayo, K. and Vallania, F. L. and Mitra, R. D. and Faber, K. and Williamson, J. and others}, title = {{Rare variants in APP, PSEN1 and PSEN2 increase risk for AD in late-onset Alzheimer's disease families}}, journal = {PloS one}, year = {2012}, doi = {10.1371/journal.pone.0031039}, pmid = {22312439}, url = {https://doi.org/10.1371/journal.pone.0031039} } @article{vardarajan2015-26101835, author = {Vardarajan, B. N. and Ghani, M. and Kahn, A. and Sheikh, S. and Sato, C. and Barral, S. and Lee, J. H. and Cheng, R. and others}, title = {{Rare coding mutations identified by sequencing of Alzheimer disease genome-wide association studies loci}}, journal = {Annals of neurology}, year = {2015}, doi = {10.1002/ana.24466}, pmid = {26101835}, url = {https://doi.org/10.1002/ana.24466} } @article{lee2007-17420311, author = {Lee, J. H. and Cheng, R. and Schupf, N. and Manly, J. and Lantigua, R. and Stern, Y. and Rogaeva, E. and Wakutani, Y. and others}, title = {{The association between genetic variants in SORL1 and Alzheimer disease in an urban, multiethnic, community-based cohort}}, journal = {Archives of neurology}, year = {2007}, doi = {10.1001/archneur.64.4.501}, pmid = {17420311}, url = {https://doi.org/10.1001/archneur.64.4.501} } @article{pickford2008-18497889, author = {Pickford, F. and Masliah, E. and Britschgi, M. and Lucin, K. and Narasimhan, R. and Jaeger, P. A. and Small, S. and Spencer, B. and others}, title = {{The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice}}, journal = {The Journal of clinical investigation}, year = {2008}, doi = {10.1172/jci33585}, pmid = {18497889}, url = {https://doi.org/10.1172/jci33585} } @article{chouraki2014-24535457, author = {Chouraki, V. and De Bruijn, R. F. and Chapuis, J. and Bis, J. C. and Reitz, C. and Schraen, S. and Ibrahim-Verbaas, C. A. and Grenier-Boley, B. and others}, title = {{A genome-wide association meta-analysis of plasma Aβ peptides concentrations in the elderly}}, journal = {Molecular psychiatry}, year = {2014}, doi = {10.1038/mp.2013.185}, pmid = {24535457}, url = {https://doi.org/10.1038/mp.2013.185} } @article{duyan1996-8751438, author = {Du Yan, Shi and Chen, Xi and Fu, Jin and Chen, Ming and Zhu, Huaijie and Roher, Alex E. and Slattery, Timothy and Zhao, Lei and Nagashima, Mariko and Morser, John and Migheli, Antonio and Nawroth, Peter P. and Stern, David M. and Schmidt, Ann Marie}, title = {{RAGE and amyloid-β peptide neurotoxicity in Alzheimer's disease}}, journal = {Nature}, year = {1996}, doi = {10.1038/382685a0}, pmid = {8751438}, url = {https://doi.org/10.1038/382685a0} } @article{quenez2026-42648288, author = {Quenez, O. and Schramm, C. and Cassinari, K. and Nicolas, A. and Groeneveld, J. and Huguet, G. and Grenier-Boley, B. and Hulsman, M. and Walters, G. B. and de Rojas, I. and Rovelet-Lecrux, A. and Feuillette, S. and others}, title = {{Exome analysis of 22,319 individuals links extremely rare copy-number variants and 22q11.21 dosage to Alzheimer risk}}, journal = {American Journal of Human Genetics}, year = {2026}, doi = {10.1016/j.ajhg.2026.07.013}, pmid = {42648288}, url = {https://doi.org/10.1016/j.ajhg.2026.07.013} } @article{lee2011-21059989, author = {Lee, J. H. and Cheng, R. and Barral, S. and Reitz, C. and Medrano, M. and Lantigua, R. and Jiménez-Velazquez, I. Z. and Rogaeva, E. and others}, title = {{Identification of novel loci for Alzheimer disease and replication of CLU, PICALM, and BIN1 in Caribbean Hispanic individuals}}, journal = {Archives of neurology}, year = {2011}, doi = {10.1001/archneurol.2010.292}, pmid = {21059989}, url = {https://doi.org/10.1001/archneurol.2010.292} } @article{devanand2005-15956169, author = {Devanand, D. P. and Pelton, G. H. and Zamora, D. and Liu, X. and Tabert, M. H. and Goodkind, M. and Scarmeas, N. and Braun, I. and others}, title = {{Predictive utility of apolipoprotein E genotype for Alzheimer disease in outpatients with mild cognitive impairment}}, journal = {Archives of neurology}, year = {2005}, doi = {10.1001/archneur.62.6.975}, pmid = {15956169}, url = {https://doi.org/10.1001/archneur.62.6.975} } @article{kunkle2025-41437928, author = {Kunkle, Brian W. and Gomez, Lissette and Tosto, Giuseppe and Rodriguez, Omar Garcia and Slifer, Susan H. and Hamilton‐Nelson, Kara L. and Naj, Adam Christian and Kushch, Nicholas A. and others}, title = {{Novel sex‐specific candidate loci associated with Alzheimer disease identified through sex‐aware multi‐ancestry genome‐wide meta‐analysis}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz70855_106407}, pmid = {41437928}, url = {https://doi.org/10.1002/alz70855_106407} } @article{areagomez2012-22892566, author = {Area-Gomez, E. and Del Carmen Lara Castillo, M. and Tambini, M. D. and Guardia-Laguarta, C. and de Groof, A. J. and Madra, M. and Ikenouchi, J. and Umeda, M. and others}, title = {{Upregulated function of mitochondria-associated ER membranes in Alzheimer disease}}, journal = {The EMBO journal}, year = {2012}, doi = {10.1038/emboj.2012.202}, pmid = {22892566}, url = {https://doi.org/10.1038/emboj.2012.202} } @article{harms2013-23588422, author = {Harms, M. and Benitez, B. A. and Cairns, N. and Cooper, B. and Cooper, P. and Mayo, K. and Carrell, D. and Faber, K. and others}, title = {{C9orf72 hexanucleotide repeat expansions in clinical Alzheimer disease}}, journal = {JAMA neurology}, year = {2013}, doi = {10.1001/2013.jamaneurol.537}, pmid = {23588422}, url = {https://doi.org/10.1001/2013.jamaneurol.537} } @article{kunkle2017-28738127, author = {Kunkle, B. W. and Vardarajan, B. N. and Naj, A. C. and Whitehead, P. L. and Rolati, S. and Slifer, S. and Carney, R. M. and Cuccaro, M. L. and others}, title = {{Early-Onset Alzheimer Disease and Candidate Risk Genes Involved in Endolysosomal Transport}}, journal = {JAMA neurology}, year = {2017}, doi = {10.1001/jamaneurol.2017.1518}, pmid = {28738127}, url = {https://doi.org/10.1001/jamaneurol.2017.1518} } @article{mayeux1993-8239575, author = {Mayeux, R. and Stern, Y. and Ottman, R. and Tatemichi, T. K. and Tang, M. X. and Maestre, G. and Ngai, C. and Tycko, B. and others}, title = {{The apolipoprotein epsilon 4 allele in patients with Alzheimer's disease}}, journal = {Annals of neurology}, year = {1993}, doi = {10.1002/ana.410340527}, pmid = {8239575}, url = {https://doi.org/10.1002/ana.410340527} } @article{patel2019-30924900, author = {Patel, D. and Mez, J. and Vardarajan, B. N. and Staley, L. and Chung, J. and Zhang, X. and Farrell, J. J. and Rynkiewicz, M. J. and others}, title = {{Association of Rare Coding Mutations With Alzheimer Disease and Other Dementias Among Adults of European Ancestry}}, journal = {JAMA network open}, year = {2019}, doi = {10.1001/jamanetworkopen.2019.1350}, pmid = {30924900}, url = {https://doi.org/10.1001/jamanetworkopen.2019.1350} } @article{cukier2016-27231719, author = {Cukier, H. N. and Kunkle, B. W. and Vardarajan, B. N. and Rolati, S. and Hamilton-Nelson, K. L. and Kohli, M. A. and Whitehead, P. L. and Dombroski, B. A. and others}, title = {{ABCA7 frameshift deletion associated with Alzheimer disease in African Americans}}, journal = {Neurology. Genetics}, year = {2016}, doi = {10.1212/nxg.0000000000000079}, pmid = {27231719}, url = {https://doi.org/10.1212/nxg.0000000000000079} } @article{barral2012-22539578, author = {Barral, S. and Bird, T. and Goate, A. and Farlow, M. R. and Diaz-Arrastia, R. and Bennett, D. A. and Graff-Radford, N. and Boeve, B. F. and others}, title = {{Genotype patterns at PICALM, CR1, BIN1, CLU, and APOE genes are associated with episodic memory}}, journal = {Neurology}, year = {2012}, doi = {10.1212/wnl.0b013e3182553c48}, pmid = {22539578}, url = {https://doi.org/10.1212/wnl.0b013e3182553c48} } @article{akgun2025-41434771, author = {Akgün, Bilçağ and Xu, Wanying and Hamilton‐Nelson, Kara L. and Nasciben, Luciana Bertholim and Scott, Kyle M. and Adams, Larry Deon and Sanchez, Jose J. and Valladares, Glenies S and others}, title = {{Significant association between SCN8A and Alzheimer disease in Puerto Ricans}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz70855_098248}, pmid = {41434771}, url = {https://doi.org/10.1002/alz70855_098248} } @article{jun2017-28183528, author = {Jun, G. R. and Chung, J. and Mez, J. and Barber, R. and Beecham, G. W. and Bennett, D. A. and Buxbaum, J. D. and Byrd, G. S. and others}, title = {{Transethnic genome-wide scan identifies novel Alzheimer's disease loci}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2017}, doi = {10.1016/j.jalz.2016.12.012}, pmid = {28183528}, url = {https://doi.org/10.1016/j.jalz.2016.12.012} } @article{li2023-37260021, author = {Li, D. and Farrell, J. J. and Mez, J. and Martin, E. R. and Bush, W. S. and Ruiz, A. and Boada, M. and de Rojas, I. and Mayeux, R. and Haines, J. L. and Vance, M. A. P. and Wang, L. S. and others}, title = {{Novel loci for Alzheimer's disease identified by a genome-wide association study in Ashkenazi Jews}}, journal = {Alzheimer's \& Dementia}, year = {2023}, doi = {10.1002/alz.13117}, pmid = {37260021}, url = {https://doi.org/10.1002/alz.13117} } @article{vardarajan2015-25382023, author = {Vardarajan, B. N. and Zhang, Y. and Lee, J. H. and Cheng, R. and Bohm, C. and Ghani, M. and Reitz, C. and Reyes-Dumeyer, D. and others}, title = {{Coding mutations in SORL1 and Alzheimer disease}}, journal = {Annals of neurology}, year = {2015}, doi = {10.1002/ana.24305}, pmid = {25382023}, url = {https://doi.org/10.1002/ana.24305} } @article{wijsman2011-21379329, author = {Wijsman, E. M. and Pankratz, N. D. and Choi, Y. and Rothstein, J. H. and Faber, K. M. and Cheng, R. and Lee, J. H. and Bird, T. D. and others}, title = {{Genome-wide association of familial late-onset Alzheimer's disease replicates BIN1 and CLU and nominates CUGBP2 in interaction with APOE}}, journal = {PLoS genetics}, year = {2011}, doi = {10.1371/journal.pgen.1001308}, pmid = {21379329}, url = {https://doi.org/10.1371/journal.pgen.1001308} } @article{schultz2023-37291760, author = {Schultz, S. A. and Shirzadi, Z. and Schultz, A. P. and Liu, L. and Fitzpatrick, C. D. and McDade, E. and Barthelemy, N. R. and Renton, A. and others}, title = {{Location of pathogenic variants in PSEN1 impacts progression of cognitive, clinical, and neurodegenerative measures in autosomal-dominant Alzheimer's disease}}, journal = {Aging cell}, year = {2023}, doi = {10.1111/acel.13871}, pmid = {37291760}, url = {https://doi.org/10.1111/acel.13871} } @article{pappolla2003-12874399, author = {Pappolla, M. A. and Bryant-Thomas, T. K. and Herbert, D. and Pacheco, J. and Fabra Garcia, M. and Manjon, M. and Girones, X. and Henry, T. L. and others}, title = {{Mild hypercholesterolemia is an early risk factor for the development of Alzheimer amyloid pathology}}, journal = {Neurology}, year = {2003}, doi = {10.1212/01.wnl.0000070182.02537.84}, pmid = {12874399}, url = {https://doi.org/10.1212/01.wnl.0000070182.02537.84} } @article{pera2017-29018038, author = {Pera, M. and Larrea, D. and Guardia-Laguarta, C. and Montesinos, J. and Velasco, K. R. and Agrawal, R. R. and Xu, Y. and Chan, R. B. and others}, title = {{Increased localization of APP-C99 in mitochondria-associated ER membranes causes mitochondrial dysfunction in Alzheimer disease}}, journal = {The EMBO journal}, year = {2017}, doi = {10.15252/embj.201796797}, pmid = {29018038}, url = {https://doi.org/10.15252/embj.201796797} } @article{sun2026-42066773, author = {Sun, X. and Mews, M. and Wheeler, N. R. and Benchek, P. and Gu, T. and Gomez, L. and Ray, N. and Reitz, C. and Naj, A. C. and Below, J. E. and Tosto, G. and Cornejo-Olivas, M. and others}, title = {{Multi-ancestry transcriptome-wide association study reveals shared and population-specific genetic effects in Alzheimer disease}}, journal = {American Journal of Human Genetics}, year = {2026}, doi = {10.1016/j.ajhg.2026.04.007}, pmid = {42066773}, url = {https://doi.org/10.1016/j.ajhg.2026.04.007} } @article{thomassen2026-42736378, author = {Thomassen, J. Q. and Leonard, H. and Ulms, B. and Grenier-Boley, B. and Heikkinen, S. and Garcia-González, P. and Castillo-Morales, A. and Kikuchi, M. and Gim, J. and Cao, H. and Küçükali, F. and Amin, N. and others}, title = {{APOE-stratified genome-wide association analyses provide insights into the genetic etiology of Alzheimers's disease}}, journal = {Nature genetics}, year = {2026}, doi = {10.1038/s41588-026-02713-9}, pmid = {42736378}, url = {https://doi.org/10.1038/s41588-026-02713-9} } @article{provenzano2013-23420027, author = {Provenzano, F. A. and Muraskin, J. and Tosto, G. and Narkhede, A. and Wasserman, B. T. and Griffith, E. Y. and Guzman, V. A. and Meier, I. B. and others}, title = {{White matter hyperintensities and cerebral amyloidosis: necessary and sufficient for clinical expression of Alzheimer disease?}}, journal = {JAMA neurology}, year = {2013}, doi = {10.1001/jamaneurol.2013.1321}, pmid = {23420027}, url = {https://doi.org/10.1001/jamaneurol.2013.1321} } @article{duyan1997-9144231, author = {Du Yan, S. and Zhu, H. and Fu, J. and Yan, S. F. and Roher, A. and Tourtellotte, W. W. and Rajavashisth, T. and Chen, X. and others}, title = {{Amyloid-beta peptide-receptor for advanced glycation endproduct interaction elicits neuronal expression of macrophage-colony stimulating factor: a proinflammatory pathway in Alzheimer disease}}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, year = {1997}, doi = {10.1073/pnas.94.10.5296}, pmid = {9144231}, url = {https://doi.org/10.1073/pnas.94.10.5296} } @article{oveisgharan2025-40845264, author = {Oveisgharan, Shahram and Yu, Lei and Yang, Jingyun and Agrawal, Sonal and Vialle, Ricardo A. and Lopes, Kátia de Paiva and Tasaki, Shinya and Wang, Yanling and others}, title = {{Cortical Gray Matter Proteins Associated With Cerebral Amyloid Angiopathy in Community-Dwelling Older Adults}}, journal = {Neurology}, year = {2025}, doi = {10.1212/wnl.0000000000214024}, pmid = {40845264}, url = {https://doi.org/10.1212/wnl.0000000000214024} } @article{puzzo2011-21472769, author = {Puzzo, D. and Privitera, L. and Fa', M. and Staniszewski, A. and Hashimoto, G. and Aziz, F. and Sakurai, M. and Ribe, E. M. and others}, title = {{Endogenous amyloid-β is necessary for hippocampal synaptic plasticity and memory}}, journal = {Annals of neurology}, year = {2011}, doi = {10.1002/ana.22313}, pmid = {21472769}, url = {https://doi.org/10.1002/ana.22313} } @article{areagomez2018-29491396, author = {Area-Gomez, E. and de Groof, A. and Bonilla, E. and Montesinos, J. and Tanji, K. and Boldogh, I. and Pon, L. and Schon, E. A.}, title = {{A key role for MAM in mediating mitochondrial dysfunction in Alzheimer disease}}, journal = {Cell death \& disease}, year = {2018}, doi = {10.1038/s41419-017-0215-0}, pmid = {29491396}, url = {https://doi.org/10.1038/s41419-017-0215-0} } @article{cohn2021-34925024, author = {Cohn, W. and Melnik, M. and Huang, C. and Teter, B. and Chandra, S. and Zhu, C. and McIntire, L. B. and John, V. and others}, title = {{Multi-Omics Analysis of Microglial Extracellular Vesicles From Human Alzheimer's Disease Brain Tissue Reveals Disease-Associated Signatures}}, journal = {Frontiers in pharmacology}, year = {2021}, doi = {10.3389/fphar.2021.766082}, pmid = {34925024}, url = {https://doi.org/10.3389/fphar.2021.766082} } @article{grossojasutkar2024-38949671, author = {Grosso Jasutkar, H. and Wasserlein, E. M. and Ishola, A. and Litt, N. and Staniszewski, A. and Arancio, O. and Yamamoto, A.}, title = {{Adult-onset deactivation of autophagy leads to loss of synapse homeostasis and cognitive impairment, with implications for alzheimer disease}}, journal = {Autophagy}, year = {2024}, doi = {10.1080/15548627.2024.2368335}, pmid = {38949671}, url = {https://doi.org/10.1080/15548627.2024.2368335} } @article{jun2012-22869155, author = {Jun, G. and Vardarajan, B. N. and Buros, J. and Yu, C. E. and Hawk, M. V. and Dombroski, B. A. and Crane, P. K. and Larson, E. B. and others}, title = {{Comprehensive search for Alzheimer disease susceptibility loci in the APOE region}}, journal = {Archives of neurology}, year = {2012}, doi = {10.1001/archneurol.2012.2052}, pmid = {22869155}, url = {https://doi.org/10.1001/archneurol.2012.2052} } @article{bis2020-30108311, author = {Bis, J. C. and Jian, X. and Kunkle, B. W. and Chen, Y. and Hamilton-Nelson, K. L. and Bush, W. S. and Salerno, W. J. and Lancour, D. and others}, title = {{Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation}}, journal = {Molecular psychiatry}, year = {2020}, doi = {10.1038/s41380-018-0112-7}, pmid = {30108311}, url = {https://doi.org/10.1038/s41380-018-0112-7} } @article{areagomez2016-27235807, author = {Area-Gomez, E. and Schon, E. A.}, title = {{Mitochondria-associated ER membranes and Alzheimer disease}}, journal = {Current opinion in genetics \& development}, year = {2016}, doi = {10.1016/j.gde.2016.04.006}, pmid = {27235807}, url = {https://doi.org/10.1016/j.gde.2016.04.006} } @article{caro2026-41906765, author = {Caro, Daniela Diaz and Rodriguez, Sophia and Uhlmann, Wendy R. and Goldman, Jill S. and McCain, Sarah and Wetmore, John Brandon and Caban, Maria L. and Chung, Wendy K. and others}, title = {{Exploring immediate responses to APOE ε 4/ε4 genotype and Alzheimer's disease risk disclosure in Latinos}}, journal = {Journal of Alzheimer s Disease}, year = {2026}, doi = {10.1177/13872877261435633}, pmid = {41906765}, url = {https://doi.org/10.1177/13872877261435633} } @article{schon2013-22922446, author = {Schon, E. A. and Area-Gomez, E.}, title = {{Mitochondria-associated ER membranes in Alzheimer disease}}, journal = {Molecular and cellular neurosciences}, year = {2013}, doi = {10.1016/j.mcn.2012.07.011}, pmid = {22922446}, url = {https://doi.org/10.1016/j.mcn.2012.07.011} } @article{moolman2004-15475691, author = {Moolman, D. L. and Vitolo, O. V. and Vonsattel, J. P. and Shelanski, M. L.}, title = {{Dendrite and dendritic spine alterations in Alzheimer models}}, journal = {Journal of neurocytology}, year = {2004}, doi = {10.1023/b:neur.0000044197.83514.64}, pmid = {15475691}, url = {https://doi.org/10.1023/b:neur.0000044197.83514.64} } @article{dodd2026-40766450, author = {Dodd, Roger B. and Enomoto, Masahiro and Zhou, Ye and Satoh, Kanayo and Zhang, Yalun and Chen, Fusheng and Acheson, Beatrice and Ghaffari, Deniz and others}, title = {{CD33 and clusterin interact biophysically and genetically to modulate Alzheimer risk}}, journal = {Nature Communications}, year = {2026}, doi = {10.1038/s41467-026-75140-3}, pmid = {40766450}, url = {https://doi.org/10.1038/s41467-026-75140-3} } @article{kurniansyah2025-41434242, author = {Kurniansyah, Nuzulul and Tasaki, Shinya and Zhu, Congcong and Farrell, John Joseph and Rehman, Habbiburr and Sherva, Richard and Hauger, Richard L. and Merritt, Victoria C. and others}, title = {{Hormone replacement therapy in women and vascular risk factors modify the association of a multi‐ancestry polygenic risk score with Alzheimer disease and related traits}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz70861_108536}, pmid = {41434242}, url = {https://doi.org/10.1002/alz70861_108536} } @article{bradley2025-41444475, author = {Bradley, Joseph L. and Western, Daniel and Wang, Ciyang and da Fonseca, Eder Lúcio and Neupane, Asmita and Kurup, Jiji Thulaseedhara and Ray, Nicholas R. and Jean‐Francois, Melissa N. and others}, title = {{Novel early‐onset Alzheimer‐associated genes influence risk through dysregulation of glutamate, immune activation, and intracell signaling pathways}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz70855_107379}, pmid = {41444475}, url = {https://doi.org/10.1002/alz70855_107379} } @article{dodd2026-c8ae3fc8, author = {Dodd, Roger B. and Enomoto, Masahiro and Zhou, Ye and Satoh, Kanayo and Zhang, Yalun and Chen, Fusheng and Acheson, Beatrice and Ghaffari, Deniz and others}, title = {{CD33 and clusterin interact biophysically and genetically to modulate Alzheimer risk}}, journal = {DOAJ (DOAJ: Directory of Open Access Journals)}, year = {2026}, doi = {10.1038/s41467-026-75140-3}, url = {https://doi.org/10.1038/s41467-026-75140-3} } @article{caro2026-dd11f0ff, author = {Caro, Ilana and Sargurupremraj, Muralidharan and Yang, Chengran and Akinleye, Callistus A. and Trégouët, David‐Alexandre and Akinyemi, Rufus and Shigemizu, Daichi and Coker, Motunrayo Mojoyin and others}, title = {{Genetic Insights Into Protective Effects of GLP-1 Receptor Agonists on Stroke and Alzheimer Disease Across Ancestries}}, journal = {Neurology Genetics}, year = {2026}, doi = {10.1212/nxg.0000000000200425}, url = {https://doi.org/10.1212/nxg.0000000000200425} } @article{ruhela2025-41447294, author = {Ruhela, Vivek and Cieza, Basilio and Mayeux, Richard P and Reyes‐Dumeyer, Dolly and Teich, Andrew F. and Tosto, Giuseppe}, title = {{Genetic Colocalization of Expression Quantitative Trait Loci (eQTL) Mapping and GWAS in a multiethnic brain bank: An Insight into ancestry‐specific Regulatory Architecture in Alzheimer's disease}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz70855_107199}, pmid = {41447294}, url = {https://doi.org/10.1002/alz70855_107199} } @article{qiang2011-21816272, author = {Qiang, L. and Fujita, R. and Yamashita, T. and Angulo, S. and Rhinn, H. and Rhee, D. and Doege, C. and Chau, L. and others}, title = {{Directed conversion of Alzheimer's disease patient skin fibroblasts into functional neurons}}, journal = {Cell}, year = {2011}, doi = {10.1016/j.cell.2011.07.007}, pmid = {21816272}, url = {https://doi.org/10.1016/j.cell.2011.07.007} }