% alzhub.org library filter
% Source: https://alzhub.org/research?institution=I4210146710&atag=precursor
% 68 entries, in the order the page lists them. Built from alzhub.org's own records.
% 0 entries have no readable author in the source record and carry no author field.

@article{naj2011-21460841,
  author  = {Naj, A. C. and Jun, G. and Beecham, G. W. and Wang, L. S. and Vardarajan, B. N. and Buros, J. and Gallins, P. J. and Buxbaum, J. D. and others},
  title   = {{Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease}},
  journal = {Nature genetics},
  year    = {2011},
  doi     = {10.1038/ng.801},
  pmid    = {21460841},
  url     = {https://doi.org/10.1038/ng.801}
}

@article{reitz2013-23571587,
  author  = {Reitz, C. and Jun, G. and Naj, A. and Rajbhandary, R. and Vardarajan, B. N. and Wang, L. S. and Valladares, O. and Lin, C. F. and others},
  title   = {{Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans}},
  journal = {JAMA},
  year    = {2013},
  doi     = {10.1001/jama.2013.2973},
  pmid    = {23571587},
  url     = {https://doi.org/10.1001/jama.2013.2973}
}

@article{kunkle2021-33074286,
  author  = {Kunkle, B. W. and Schmidt, M. and Klein, H. U. and Naj, A. C. and Hamilton-Nelson, K. L. and Larson, E. B. and Evans, D. A. and De Jager, P. L. and others},
  title   = {{Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis}},
  journal = {JAMA neurology},
  year    = {2021},
  doi     = {10.1001/jamaneurol.2020.3536},
  pmid    = {33074286},
  url     = {https://doi.org/10.1001/jamaneurol.2020.3536}
}

@article{rajabli2025-40676597,
  author  = {Rajabli, F. and Benchek, P. and Tosto, G. and Kushch, N. and Sha, J. and Bazemore, K. and Zhu, C. and Lee, W. P. and others},
  title   = {{Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies known and novel cross-population and ancestry-specific associations as novel risk loci for Alzheimer's disease}},
  journal = {Genome biology},
  year    = {2025},
  doi     = {10.1186/s13059-025-03564-z},
  pmid    = {40676597},
  url     = {https://doi.org/10.1186/s13059-025-03564-z}
}

@article{leguen2023-36809323,
  author  = {Le Guen, Y. and Raulin, A. C. and Logue, M. W. and Sherva, R. and Belloy, M. E. and Eger, S. J. and Chen, A. and Kennedy, G. and Kuchenbecker, L. and O'Leary, J. P. and Zhang, R. and Merritt, V. C. and others},
  title   = {{Association of African Ancestry-Specific APOE Missense Variant R145C With Risk of Alzheimer Disease}},
  journal = {JAMA},
  year    = {2023},
  doi     = {10.1001/jama.2023.0268},
  pmid    = {36809323},
  url     = {https://doi.org/10.1001/jama.2023.0268}
}

@article{bhattarai2024-38598053,
  author  = {Bhattarai, P. and Gunasekaran, T. I. and Belloy, M. E. and Reyes-Dumeyer, D. and Jülich, D. and Tayran, H. and Yilmaz, E. and Flaherty, D. and Turgutalp, B. and Sukumar, G. and Alba, C. and McGrath, E. M. and others},
  title   = {{Rare genetic variation in fibronectin 1 (FN1) protects against APOEε4 in Alzheimer's disease}},
  journal = {Acta Neuropathologica},
  year    = {2024},
  doi     = {10.1007/s00401-024-02721-1},
  pmid    = {38598053},
  url     = {https://doi.org/10.1007/s00401-024-02721-1}
}

@article{naj2014-25199842,
  author  = {Naj, A. C. and Jun, G. and Reitz, C. and Kunkle, B. W. and Perry, W. and Park, Y. S. and Beecham, G. W. and Rajbhandary, R. A. and others},
  title   = {{Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study}},
  journal = {JAMA neurology},
  year    = {2014},
  doi     = {10.1001/jamaneurol.2014.1491},
  pmid    = {25199842},
  url     = {https://doi.org/10.1001/jamaneurol.2014.1491}
}

@article{broce2018-29315334,
  author  = {Broce, I. and Karch, C. M. and Wen, N. and Fan, C. C. and Wang, Y. and Tan, C. H. and Kouri, N. and Ross, O. A. and others},
  title   = {{Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies}},
  journal = {PLoS medicine},
  year    = {2018},
  doi     = {10.1371/journal.pmed.1002487},
  pmid    = {29315334},
  url     = {https://doi.org/10.1371/journal.pmed.1002487}
}

@article{dube2019-31591557,
  author  = {Dube, U. and Del-Aguila, J. L. and Li, Z. and Budde, J. P. and Jiang, S. and Hsu, S. and Ibanez, L. and Fernandez, M. V. and others},
  title   = {{An atlas of cortical circular RNA expression in Alzheimer disease brains demonstrates clinical and pathological associations}},
  journal = {Nature neuroscience},
  year    = {2019},
  doi     = {10.1038/s41593-019-0501-5},
  pmid    = {31591557},
  url     = {https://doi.org/10.1038/s41593-019-0501-5}
}

@article{caselli2009-19605830,
  author  = {Caselli, R. J. and Dueck, A. C. and Osborne, D. and Sabbagh, M. N. and Connor, D. J. and Ahern, G. L. and Baxter, L. C. and Rapcsak, S. Z. and others},
  title   = {{Longitudinal modeling of age-related memory decline and the APOE epsilon4 effect}},
  journal = {The New England journal of medicine},
  year    = {2009},
  doi     = {10.1056/nejmoa0809437},
  pmid    = {19605830},
  url     = {https://doi.org/10.1056/nejmoa0809437}
}

@article{chouraki2015-25217292,
  author  = {Chouraki, V. and Beiser, A. and Younkin, L. and Preis, SR. and Weinstein, G. and Hansson, O. and Skoog, I. and Lambert, J. C. and others},
  title   = {{Plasma amyloid-β and risk of Alzheimer's disease in the Framingham Heart Study}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2015},
  doi     = {10.1016/j.jalz.2014.07.001},
  pmid    = {25217292},
  url     = {https://doi.org/10.1016/j.jalz.2014.07.001}
}

@article{shirzadi2023-37843849,
  author  = {Shirzadi, Z. and Schultz, S. A. and Yau, W. W. and Joseph-Mathurin, N. and Fitzpatrick, C. D. and Levin, R. and Kantarci, K. and Preboske, G. M. and others},
  title   = {{Etiology of White Matter Hyperintensities in Autosomal Dominant and Sporadic Alzheimer Disease}},
  journal = {JAMA neurology},
  year    = {2023},
  doi     = {10.1001/jamaneurol.2023.3618},
  pmid    = {37843849},
  url     = {https://doi.org/10.1001/jamaneurol.2023.3618}
}

@article{murray2015-25805643,
  author  = {Murray, M. E. and Lowe, V. J. and Graff-Radford, N. R. and Liesinger, A. M. and Cannon, A. and Przybelski, S. A. and Rawal, B. and Parisi, J. E. and others},
  title   = {{Clinicopathologic and 11C-Pittsburgh compound B implications of Thal amyloid phase across the Alzheimer's disease spectrum}},
  journal = {Brain : a journal of neurology},
  year    = {2015},
  doi     = {10.1093/brain/awv050},
  pmid    = {25805643},
  url     = {https://doi.org/10.1093/brain/awv050}
}

@article{carrasquillo2010-20554627,
  author  = {Carrasquillo, M. M. and Belbin, O. and Hunter, T. A. and Ma, L. and Bisceglio, G. D. and Zou, F. and Crook, J. E. and others},
  title   = {{Replication of CLU, CR1, and PICALM associations with alzheimer disease}},
  journal = {Archives of neurology},
  year    = {2010},
  doi     = {10.1001/archneurol.2010.147},
  pmid    = {20554627},
  url     = {https://doi.org/10.1001/archneurol.2010.147}
}

@article{harold2009-19734902,
  author  = {Harold, Denise H. and Abraham, Richard and Hollingworth, Paul and Sims, Rebecca and Gerrish, Amy and Hamshere, Marian L. and Pahwa, Jaspreet Singh and Moskvina, Valentina and others},
  title   = {{Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease}},
  journal = {Nature Genetics},
  year    = {2009},
  doi     = {10.1038/ng.440},
  pmid    = {19734902},
  url     = {https://doi.org/10.1038/ng.440}
}

@article{study2011-21460840,
  author  = {{the Alzheimer's Disease Neuroimaging Initiative} and Hollingworth, Paul and Harold, Denise H. and Sims, Rebecca and Gerrish, Amy and Lambert, Jean‐Charles and Carrasquillo, Minerva M. and Abraham, Richard and others},
  title   = {{Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease}},
  journal = {Nature Genetics},
  year    = {2011},
  doi     = {10.1038/ng.803},
  pmid    = {21460840},
  url     = {https://doi.org/10.1038/ng.803}
}

@article{raya2026-41729539,
  author  = {Raya, Maison Abu and Suemoto, Claudia Kimie and Paes, Vitor Ribeiro and Leite, Renata Elaine Paraizo and Pasqualucci, Carlos Augusto and Naslavsky, Michel Satya and Rodriguez, Roberta Diehl and Nitrini, Ricardo and others},
  title   = {{Sex Differences in Amyloid Pathology by Race, Ancestry, and Apolipoprotein E ε4 in an Admixed Autopsy Sample}},
  journal = {JAMA neurology},
  year    = {2026},
  doi     = {10.1001/jamaneurol.2026.0054},
  pmid    = {41729539},
  url     = {https://doi.org/10.1001/jamaneurol.2026.0054}
}

@article{oddo2003-12895417,
  author  = {Oddo, Salvatore and Caccamo, Antonella and Shepherd, Jason D. and Murphy, Michael Paul and Golde, Todd Eliot and Kayed, Rakez and Metherate, Raju and Mattson, Mark P. and others},
  title   = {{Triple-Transgenic Model of Alzheimer's Disease with Plaques and Tangles}},
  journal = {Neuron},
  year    = {2003},
  doi     = {10.1016/s0896-6273(03)00434-3},
  pmid    = {12895417},
  url     = {https://doi.org/10.1016/s0896-6273(03)00434-3}
}

@article{schultz2024-39074479,
  author  = {Schultz, S. A. and Liu, L. and Schultz, A. P. and Fitzpatrick, C. D. and Levin, R. and Bellier, J. P. and Shirzadi, Z. and Joseph-Mathurin, N. and others},
  title   = {{γ-Secretase activity, clinical features, and biomarkers of autosomal dominant Alzheimer's disease: cross-sectional and longitudinal analysis of the Dominantly Inherited Alzheimer Network observational study (DIAN-OBS)}},
  journal = {The Lancet. Neurology},
  year    = {2024},
  doi     = {10.1016/s1474-4422(24)00236-9},
  pmid    = {39074479},
  url     = {https://doi.org/10.1016/s1474-4422(24)00236-9}
}

@article{allen2012-22722634,
  author  = {Allen, M. and Zou, F. and Chai, H. S. and Younkin, C. S. and Crook, J. and Pankratz, V. S. and Carrasquillo, M. M. and Rowley, C. N. and others},
  title   = {{Novel late-onset Alzheimer disease loci variants associate with brain gene expression}},
  journal = {Neurology},
  year    = {2012},
  doi     = {10.1212/wnl.0b013e3182605801},
  pmid    = {22722634},
  url     = {https://doi.org/10.1212/wnl.0b013e3182605801}
}

@article{hsiao1996-8810256,
  author  = {Hsiao, Karen and Chapman, Paul F. and Nilsen, Steven P. and Eckman, Chris and Harigaya, Yasuo and Younkin, Steven G. and Yang, Fusheng and Cole, Greg M.},
  title   = {{Correlative Memory Deficits, Aβ Elevation, and Amyloid Plaques in Transgenic Mice}},
  journal = {Science},
  year    = {1996},
  doi     = {10.1126/science.274.5284.99},
  pmid    = {8810256},
  url     = {https://doi.org/10.1126/science.274.5284.99}
}

@article{dickson2018-30143564,
  author  = {Dickson, D. W. and Heckman, M. G. and Murray, M. E. and Soto, A. I. and Walton, R. L. and Diehl, N. N. and van Gerpen, J. A. and Uitti, R. J. and others},
  title   = {{APOE ε4 is associated with severity of Lewy body pathology independent of Alzheimer pathology}},
  journal = {Neurology},
  year    = {2018},
  doi     = {10.1212/wnl.0000000000006212},
  pmid    = {30143564},
  url     = {https://doi.org/10.1212/wnl.0000000000006212}
}

@article{reiman2020-32015339,
  author  = {Reiman, E. M. and Arboleda-Velasquez, J. F. and Quiroz, Y. T. and Huentelman, M. J. and Beach, T. G. and Caselli, R. J. and Chen, Y. and Su, Y. and others},
  title   = {{Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study}},
  journal = {Nature communications},
  year    = {2020},
  doi     = {10.1038/s41467-019-14279-8},
  pmid    = {32015339},
  url     = {https://doi.org/10.1038/s41467-019-14279-8}
}

@article{rogaeva2007-17220890,
  author  = {Rogaeva, E. and Meng, Y. and Lee, J. H. and Gu, Y. and Kawarai, T. and Zou, F. and Katayama, T. and Baldwin, C. T. and others},
  title   = {{The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease}},
  journal = {Nature genetics},
  year    = {2007},
  doi     = {10.1038/ng1943},
  pmid    = {17220890},
  url     = {https://doi.org/10.1038/ng1943}
}

@article{cruchaga2012-22312439,
  author  = {Cruchaga, C. and Haller, G. and Chakraverty, S. and Mayo, K. and Vallania, F. L. and Mitra, R. D. and Faber, K. and Williamson, J. and others},
  title   = {{Rare variants in APP, PSEN1 and PSEN2 increase risk for AD in late-onset Alzheimer's disease families}},
  journal = {PloS one},
  year    = {2012},
  doi     = {10.1371/journal.pone.0031039},
  pmid    = {22312439},
  url     = {https://doi.org/10.1371/journal.pone.0031039}
}

@article{scheuner1996-8705854,
  author  = {Scheuner, Donalyn and Eckman, Christopher B. and Jensen, M. and Song, X.H. and Citron, Martin and Suzuki, Nobuhiro and Bird, Thomas D. and Hardy, John and Hutton, Melanie L. and Kukull, Walter A. and Larson, Eric B. and Levy‐Lahad, Ephrat and Viitanen, Matti H. and Peskind, Elaine R. and Poorkaj, Parvoneh and Schellenberg, Gerald D. and Tanzi, Rudolph E. and Wasco, Wilma and Lannfelt, Lars and Selkoe, Dennis J. and Younkin, Samuel G.},
  title   = {{Secreted amyloid β–protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease}},
  journal = {Nature Medicine},
  year    = {1996},
  doi     = {10.1038/nm0896-864},
  pmid    = {8705854},
  url     = {https://doi.org/10.1038/nm0896-864}
}

@article{graffradford2002-11939894,
  author  = {Graff-Radford, N. R. and Green, R. C. and Go, R. C. and Hutton, M. L. and Edeki, T. and Bachman, D. and Adamson, J. L. and Griffith, P. and others},
  title   = {{Association between apolipoprotein E genotype and Alzheimer disease in African American subjects}},
  journal = {Archives of neurology},
  year    = {2002},
  doi     = {10.1001/archneur.59.4.594},
  pmid    = {11939894},
  url     = {https://doi.org/10.1001/archneur.59.4.594}
}

@article{zhao2020-33139712,
  author  = {Zhao, J. and Fu, Y. and Yamazaki, Y. and Ren, Y. and Davis, M. D. and Liu, C. C. and Lu, W. and Wang, X. and others},
  title   = {{APOE4 exacerbates synapse loss and neurodegeneration in Alzheimer's disease patient iPSC-derived cerebral organoids}},
  journal = {Nature communications},
  year    = {2020},
  doi     = {10.1038/s41467-020-19264-0},
  pmid    = {33139712},
  url     = {https://doi.org/10.1038/s41467-020-19264-0}
}

@article{martens2022-35298921,
  author  = {Martens, Y. A. and Zhao, N. and Liu, C. C. and Kanekiyo, T. and Yang, A. J. and Goate, A. M. and Holtzman, D. M. and Bu, G.},
  title   = {{ApoE Cascade Hypothesis in the pathogenesis of Alzheimer's disease and related dementias}},
  journal = {Neuron},
  year    = {2022},
  doi     = {10.1016/j.neuron.2022.03.004},
  pmid    = {35298921},
  url     = {https://doi.org/10.1016/j.neuron.2022.03.004}
}

@article{holcomb1998-9427614,
  author  = {Holcomb, L. and Gordon, M. N. and McGowan, E. and Yu, X. and Benkovic, S. and Jantzen, P. and Wright, K. and Saad, I. and others},
  title   = {{Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes}},
  journal = {Nature medicine},
  year    = {1998},
  doi     = {10.1038/nm0198-097},
  pmid    = {9427614},
  url     = {https://doi.org/10.1038/nm0198-097}
}

@article{graffradford2007-17353377,
  author  = {Graff-Radford, N. R. and Crook, J. E. and Lucas, J. and Boeve, B. F. and Knopman, D. S. and Ivnik, R. J. and Smith, G. E. and Younkin, L. H. and others},
  title   = {{Association of low plasma Abeta42/Abeta40 ratios with increased imminent risk for mild cognitive impairment and Alzheimer disease}},
  journal = {Archives of neurology},
  year    = {2007},
  doi     = {10.1001/archneur.64.3.354},
  pmid    = {17353377},
  url     = {https://doi.org/10.1001/archneur.64.3.354}
}

@article{o2025-39652363,
  author  = {Ö, İş and Min, Y. and Wang, X. and Oatman, SR. and Abraham Daniel, A. and Ertekin-Taner, N.},
  title   = {{Multi Layered Omics Approaches Reveal Glia Specific Alterations in Alzheimer's Disease: A Systematic Review and Future Prospects}},
  journal = {Glia},
  year    = {2025},
  doi     = {10.1002/glia.24652},
  pmid    = {39652363},
  url     = {https://doi.org/10.1002/glia.24652}
}

@article{weggen2001-11700559,
  author  = {Weggen, Sascha and Eriksen, Jason L. and Das, Pritam and Sagi, Sarah A. and Wang, Rong and Pietrzik, Claus U. and Findlay, Kirk A. and Smith, Tawnya E. and Murphy, Michael P. and Bülter, Thomas and Kang, David E. and Marquez-Sterling, Numa R. and Golde, Todd Eliot and Koo, Edward H.},
  title   = {{A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity}},
  journal = {Nature},
  year    = {2001},
  doi     = {10.1038/35102591},
  pmid    = {11700559},
  url     = {https://doi.org/10.1038/35102591}
}

@article{morris2022-35580594,
  author  = {Morris, J. C. and Weiner, M. and Xiong, C. and Beckett, L. and Coble, D. and Saito, N. and Aisen, P. S. and Allegri, R. and others},
  title   = {{Autosomal dominant and sporadic late onset Alzheimer's disease share a common in vivo pathophysiology}},
  journal = {Brain : a journal of neurology},
  year    = {2022},
  doi     = {10.1093/brain/awac181},
  pmid    = {35580594},
  url     = {https://doi.org/10.1093/brain/awac181}
}

@article{liu2013-23296339,
  author  = {Liu, C. C. and Kanekiyo, T. and Xu, H. and Bu, G.},
  title   = {{Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy}},
  journal = {Nature reviews. Neurology},
  year    = {2013},
  doi     = {10.1038/nrneurol.2012.263},
  pmid    = {23296339},
  url     = {https://doi.org/10.1038/nrneurol.2012.263}
}

@article{harms2013-23588422,
  author  = {Harms, M. and Benitez, B. A. and Cairns, N. and Cooper, B. and Cooper, P. and Mayo, K. and Carrell, D. and Faber, K. and others},
  title   = {{C9orf72 hexanucleotide repeat expansions in clinical Alzheimer disease}},
  journal = {JAMA neurology},
  year    = {2013},
  doi     = {10.1001/2013.jamaneurol.537},
  pmid    = {23588422},
  url     = {https://doi.org/10.1001/2013.jamaneurol.537}
}

@article{jones2010-21085570,
  author  = {Jones, L. and Holmans, P. A. and Hamshere, M. L. and Harold, D. and Moskvina, V. and Ivanov, D. and Pocklington, A. and Abraham, R. and others},
  title   = {{Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease}},
  journal = {PloS one},
  year    = {2010},
  doi     = {10.1371/journal.pone.0013950},
  pmid    = {21085570},
  url     = {https://doi.org/10.1371/journal.pone.0013950}
}

@article{allen2012-22494505,
  author  = {Allen, M. and Zou, F. and Chai, H. S. and Younkin, C. S. and Miles, R. and Nair, A. A. and Crook, J. E. and Pankratz, V. S. and others},
  title   = {{Glutathione S-transferase omega genes in Alzheimer and Parkinson disease risk, age-at-diagnosis and brain gene expression: an association study with mechanistic implications}},
  journal = {Molecular neurodegeneration},
  year    = {2012},
  doi     = {10.1186/1750-1326-7-13},
  pmid    = {22494505},
  url     = {https://doi.org/10.1186/1750-1326-7-13}
}

@article{barral2012-22539578,
  author  = {Barral, S. and Bird, T. and Goate, A. and Farlow, M. R. and Diaz-Arrastia, R. and Bennett, D. A. and Graff-Radford, N. and Boeve, B. F. and others},
  title   = {{Genotype patterns at PICALM, CR1, BIN1, CLU, and APOE genes are associated with episodic memory}},
  journal = {Neurology},
  year    = {2012},
  doi     = {10.1212/wnl.0b013e3182553c48},
  pmid    = {22539578},
  url     = {https://doi.org/10.1212/wnl.0b013e3182553c48}
}

@article{yamazaki2019-31367008,
  author  = {Yamazaki, Y. and Zhao, N. and Caulfield, T. R. and Liu, C. C. and Bu, G.},
  title   = {{Apolipoprotein E and Alzheimer disease: pathobiology and targeting strategies}},
  journal = {Nature reviews. Neurology},
  year    = {2019},
  doi     = {10.1038/s41582-019-0228-7},
  pmid    = {31367008},
  url     = {https://doi.org/10.1038/s41582-019-0228-7}
}

@article{jun2017-28183528,
  author  = {Jun, G. R. and Chung, J. and Mez, J. and Barber, R. and Beecham, G. W. and Bennett, D. A. and Buxbaum, J. D. and Byrd, G. S. and others},
  title   = {{Transethnic genome-wide scan identifies novel Alzheimer's disease loci}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2017},
  doi     = {10.1016/j.jalz.2016.12.012},
  pmid    = {28183528},
  url     = {https://doi.org/10.1016/j.jalz.2016.12.012}
}

@article{zhao2020-32199103,
  author  = {Zhao, N. and Ren, Y. and Yamazaki, Y. and Qiao, W. and Li, F. and Felton, L. M. and Mahmoudiandehkordi, S. and Kueider-Paisley, A. and others},
  title   = {{Alzheimer's Risk Factors Age, APOE Genotype, and Sex Drive Distinct Molecular Pathways}},
  journal = {Neuron},
  year    = {2020},
  doi     = {10.1016/j.neuron.2020.02.034},
  pmid    = {32199103},
  url     = {https://doi.org/10.1016/j.neuron.2020.02.034}
}

@article{sando2008-18416843,
  author  = {Sando, S. B. and Melquist, S. and Cannon, A. and Hutton, M. L. and Sletvold, O. and Saltvedt, I. and White, L. R. and Lydersen, S. and others},
  title   = {{APOE epsilon 4 lowers age at onset and is a high risk factor for Alzheimer's disease; a case control study from central Norway}},
  journal = {BMC neurology},
  year    = {2008},
  doi     = {10.1186/1471-2377-8-9},
  pmid    = {18416843},
  url     = {https://doi.org/10.1186/1471-2377-8-9}
}

@article{park2017-28515043,
  author  = {Park, L. and Uekawa, K. and Garcia-Bonilla, L. and Koizumi, K. and Murphy, M. and Pistik, R. and Younkin, L. and Younkin, S. and others},
  title   = {{Brain Perivascular Macrophages Initiate the Neurovascular Dysfunction of Alzheimer Aβ Peptides}},
  journal = {Circulation research},
  year    = {2017},
  doi     = {10.1161/circresaha.117.311054},
  pmid    = {28515043},
  url     = {https://doi.org/10.1161/circresaha.117.311054}
}

@article{schultz2023-37291760,
  author  = {Schultz, S. A. and Shirzadi, Z. and Schultz, A. P. and Liu, L. and Fitzpatrick, C. D. and McDade, E. and Barthelemy, N. R. and Renton, A. and others},
  title   = {{Location of pathogenic variants in PSEN1 impacts progression of cognitive, clinical, and neurodegenerative measures in autosomal-dominant Alzheimer's disease}},
  journal = {Aging cell},
  year    = {2023},
  doi     = {10.1111/acel.13871},
  pmid    = {37291760},
  url     = {https://doi.org/10.1111/acel.13871}
}

@article{holtzman2012-22393530,
  author  = {Holtzman, D. M. and Herz, J. and Bu, G.},
  title   = {{Apolipoprotein E and apolipoprotein E receptors: normal biology and roles in Alzheimer disease}},
  journal = {Cold Spring Harbor perspectives in medicine},
  year    = {2012},
  doi     = {10.1101/cshperspect.a006312},
  pmid    = {22393530},
  url     = {https://doi.org/10.1101/cshperspect.a006312}
}

@article{caselli2007-17846270,
  author  = {Caselli, R. J. and Reiman, E. M. and Locke, D. E. and Hutton, M. L. and Hentz, J. G. and Hoffman-Snyder, C. and Woodruff, B. K. and Alexander, G. E. and others},
  title   = {{Cognitive domain decline in healthy apolipoprotein E epsilon4 homozygotes before the diagnosis of mild cognitive impairment}},
  journal = {Archives of neurology},
  year    = {2007},
  doi     = {10.1001/archneur.64.9.1306},
  pmid    = {17846270},
  url     = {https://doi.org/10.1001/archneur.64.9.1306}
}

@article{destrooper2010-20139999,
  author  = {De Strooper, B. and Vassar, R. and Golde, T.},
  title   = {{The secretases: enzymes with therapeutic potential in Alzheimer disease}},
  journal = {Nature reviews. Neurology},
  year    = {2010},
  doi     = {10.1038/nrneurol.2009.218},
  pmid    = {20139999},
  url     = {https://doi.org/10.1038/nrneurol.2009.218}
}

@article{youmans2012-23060451,
  author  = {Youmans, K. L. and Tai, L. M. and Nwabuisi-Heath, E. and Jungbauer, L. and Kanekiyo, T. and Gan, M. and Kim, J. and Eimer, W. A. and others},
  title   = {{APOE4-specific changes in Aβ accumulation in a new transgenic mouse model of Alzheimer disease}},
  journal = {The Journal of biological chemistry},
  year    = {2012},
  doi     = {10.1074/jbc.m112.407957},
  pmid    = {23060451},
  url     = {https://doi.org/10.1074/jbc.m112.407957}
}

@article{tai2013-23293020,
  author  = {Tai, L. M. and Bilousova, T. and Jungbauer, L. and Roeske, S. K. and Youmans, K. L. and Yu, C. and Poon, W. W. and Cornwell, L. B. and others},
  title   = {{Levels of soluble apolipoprotein E/amyloid-β (Aβ) complex are reduced and oligomeric Aβ increased with APOE4 and Alzheimer disease in a transgenic mouse model and human samples}},
  journal = {The Journal of biological chemistry},
  year    = {2013},
  doi     = {10.1074/jbc.m112.442103},
  pmid    = {23293020},
  url     = {https://doi.org/10.1074/jbc.m112.442103}
}

@article{jankowsky2005-15917461,
  author  = {Jankowsky, J. L. and Melnikova, T. and Fadale, D. J. and Xu, G. M. and Slunt, H. H. and Gonzales, V. and Younkin, L. H. and Younkin, S. G. and others},
  title   = {{Environmental enrichment mitigates cognitive deficits in a mouse model of Alzheimer's disease}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2005},
  doi     = {10.1523/jneurosci.5080-04.2005},
  pmid    = {15917461},
  url     = {https://doi.org/10.1523/jneurosci.5080-04.2005}
}

@article{hsiao1995-7576662,
  author  = {Hsiao, K. K. and Borchelt, D. R. and Olson, K. and Johannsdottir, R. and Kitt, C. and Yunis, W. and Xu, S. and Eckman, C. and others},
  title   = {{Age-related CNS disorder and early death in transgenic FVB/N mice overexpressing Alzheimer amyloid precursor proteins}},
  journal = {Neuron},
  year    = {1995},
  doi     = {10.1016/0896-6273(95)90107-8},
  pmid    = {7576662},
  url     = {https://doi.org/10.1016/0896-6273(95)90107-8}
}

@article{kanekiyo2014-24904407,
  author  = {Kanekiyo, T. and Bu, G.},
  title   = {{The low-density lipoprotein receptor-related protein 1 and amyloid-β clearance in Alzheimer's disease}},
  journal = {Frontiers in aging neuroscience},
  year    = {2014},
  doi     = {10.3389/fnagi.2014.00093},
  pmid    = {24904407},
  url     = {https://doi.org/10.3389/fnagi.2014.00093}
}

@article{jankowsky2005-16279840,
  author  = {Jankowsky, J. L. and Slunt, H. H. and Gonzales, V. and Savonenko, A. V. and Wen, J. C. and Jenkins, N. A. and Copeland, N. G. and Younkin, L. H. and others},
  title   = {{Persistent amyloidosis following suppression of Abeta production in a transgenic model of Alzheimer disease}},
  journal = {PLoS medicine},
  year    = {2005},
  doi     = {10.1371/journal.pmed.0020355},
  pmid    = {16279840},
  url     = {https://doi.org/10.1371/journal.pmed.0020355}
}

@article{liao2017-27922847,
  author  = {Liao, F. and Yoon, H. and Kim, J.},
  title   = {{Apolipoprotein E metabolism and functions in brain and its role in Alzheimer's disease}},
  journal = {Current opinion in lipidology},
  year    = {2017},
  doi     = {10.1097/mol.0000000000000383},
  pmid    = {27922847},
  url     = {https://doi.org/10.1097/mol.0000000000000383}
}

@article{li2012-23132858,
  author  = {Li, J. and Kanekiyo, T. and Shinohara, M. and Zhang, Y. and LaDu, M. J. and Xu, H. and Bu, G.},
  title   = {{Differential regulation of amyloid-β endocytic trafficking and lysosomal degradation by apolipoprotein E isoforms}},
  journal = {The Journal of biological chemistry},
  year    = {2012},
  doi     = {10.1074/jbc.m112.420224},
  pmid    = {23132858},
  url     = {https://doi.org/10.1074/jbc.m112.420224}
}

@article{malik2015-26438529,
  author  = {Malik, M. and Parikh, I. and Vasquez, J. B. and Smith, C. and Tai, L. and Bu, G. and LaDu, M. J. and Fardo, D. W. and others},
  title   = {{Genetics ignite focus on microglial inflammation in Alzheimer's disease}},
  journal = {Molecular neurodegeneration},
  year    = {2015},
  doi     = {10.1186/s13024-015-0048-1},
  pmid    = {26438529},
  url     = {https://doi.org/10.1186/s13024-015-0048-1}
}

@article{matsuda2005-15983050,
  author  = {Matsuda, S. and Giliberto, L. and Matsuda, Y. and Davies, P. and McGowan, E. and Pickford, F. and Ghiso, J. and Frangione, B. and others},
  title   = {{The familial dementia BRI2 gene binds the Alzheimer gene amyloid-beta precursor protein and inhibits amyloid-beta production}},
  journal = {The Journal of biological chemistry},
  year    = {2005},
  doi     = {10.1074/jbc.c500217200},
  pmid    = {15983050},
  url     = {https://doi.org/10.1074/jbc.c500217200}
}

@article{jankowsky2007-17556372,
  author  = {Jankowsky, J. L. and Younkin, L. H. and Gonzales, V. and Fadale, D. J. and Slunt, H. H. and Lester, H. A. and Younkin, S. G. and Borchelt, D. R.},
  title   = {{Rodent A beta modulates the solubility and distribution of amyloid deposits in transgenic mice}},
  journal = {The Journal of biological chemistry},
  year    = {2007},
  doi     = {10.1074/jbc.m611050200},
  pmid    = {17556372},
  url     = {https://doi.org/10.1074/jbc.m611050200}
}

@article{pottier2016-27658901,
  author  = {Pottier, C. and Ravenscroft, T. A. and Brown, P. H. and Finch, N. A. and Baker, M. and Parsons, M. and Asmann, Y. W. and Ren, Y. and others},
  title   = {{TYROBP genetic variants in early-onset Alzheimer's disease}},
  journal = {Neurobiology of aging},
  year    = {2016},
  doi     = {10.1016/j.neurobiolaging.2016.07.028},
  pmid    = {27658901},
  url     = {https://doi.org/10.1016/j.neurobiolaging.2016.07.028}
}

@article{mori2001-11487052,
  author  = {Mori, T. and Paris, D. and Town, T. and Rojiani, A. M. and Sparks, D. L. and Delledonne, A. and Crawford, F. and Abdullah, L. I. and others},
  title   = {{Cholesterol accumulates in senile plaques of Alzheimer disease patients and in transgenic APP(SW) mice}},
  journal = {Journal of neuropathology and experimental neurology},
  year    = {2001},
  doi     = {10.1093/jnen/60.8.778},
  pmid    = {11487052},
  url     = {https://doi.org/10.1093/jnen/60.8.778}
}

@article{holstege2025-41442609,
  author  = {Holstege, Henne H. and Salazar, Alex and Knoop, Lydian and Pijnenburg, Yolande A.L. and van der Lee, Sven J and Wijesekera, Sanduni and Křížová, Jana and Hiltunen, Mikko O. and others},
  title   = {{Fine‐mapping of the TMEM106B locus reveals four haplotypes that are differentially associated with risk for neurodegeneration}},
  journal = {Alzheimer s \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz70855_104407},
  pmid    = {41442609},
  url     = {https://doi.org/10.1002/alz70855_104407}
}

@article{carlson1997-9302276,
  author  = {Carlson, G. A. and Borchelt, D. R. and Dake, A. and Turner, S. and Danielson, V. and Coffin, J. D. and Eckman, C. and Meiners, J. and others},
  title   = {{Genetic modification of the phenotypes produced by amyloid precursor protein overexpression in transgenic mice}},
  journal = {Human molecular genetics},
  year    = {1997},
  doi     = {10.1093/hmg/6.11.1951},
  pmid    = {9302276},
  url     = {https://doi.org/10.1093/hmg/6.11.1951}
}

@article{le2001-11706935,
  author  = {Le, T. V. and Crook, R. and Hardy, J. and Dickson, D. W.},
  title   = {{Cotton wool plaques in non-familial late-onset Alzheimer disease}},
  journal = {Journal of neuropathology and experimental neurology},
  year    = {2001},
  doi     = {10.1093/jnen/60.11.1051},
  pmid    = {11706935},
  url     = {https://doi.org/10.1093/jnen/60.11.1051}
}

@article{kapadia2026-42681024,
  author  = {Kapadia, Akshay and Schuhmann, Fabian and Daşkın, Ezgi and Walter, Jochen and Lindahl, Isabell and Rahmani, Neda and Morrema, Tjado H. J. and Rozemüller, Annemieke J.M. and others},
  title   = {{Presynaptic accumulation of APP-CTFβ may contribute to synaptic dysfunction in Alzheimer’s disease}},
  journal = {The EMBO Journal},
  year    = {2026},
  doi     = {10.1038/s44318-026-00899-6},
  pmid    = {42681024},
  url     = {https://doi.org/10.1038/s44318-026-00899-6}
}

@article{basun2002-12218259,
  author  = {Basun, H. and Nilsberth, C. and Eckman, C. and Lannfelt, L. and Younkin, S.},
  title   = {{Plasma levels of Abeta42 and Abeta40 in Alzheimer patients during treatment with the acetylcholinesterase inhibitor tacrine}},
  journal = {Dementia and geriatric cognitive disorders},
  year    = {2002},
  doi     = {10.1159/000063605},
  pmid    = {12218259},
  url     = {https://doi.org/10.1159/000063605}
}

@article{ramanan2025-40703204,
  author  = {Ramanan, Vijay K. and Heckman, Michael G. and Hofrenning, Ekaterina I. and Przybelski, Scott A. and Graff‐Radford, Jonathan and Lowe, Val J. and Machulda, Mary M. and Murray, Melissa Erin and others},
  title   = {{Combating Genetic Heterogeneity for Polygenic Prediction of Susceptibility to Brain β-Amyloid Deposition}},
  journal = {Neurology Genetics},
  year    = {2025},
  doi     = {10.1212/nxg.0000000000200266},
  pmid    = {40703204},
  url     = {https://doi.org/10.1212/nxg.0000000000200266}
}

@article{salazar2026-28f7dc41,
  author  = {Salazar, A. and Tesi, N. and Knoop, L. and van Schoor, N. M. and Huisman, M. and Tijms, B. and Vijverberg, E. G. B. and der Lee, van and others},
  title   = {{Fine-mapping reveals four TMEM106B haplotypes associated with neurodegenerative risk and preserved cognition at extreme age}},
  journal = {medRxiv (preprint)},
  year    = {2026},
  doi     = {10.1101/2025.02.02.25321330},
  url     = {https://doi.org/10.1101/2025.02.02.25321330}
}