% alzhub.org library filter % Source: https://alzhub.org/research?category=mechanisms&atag=phosphorylation % 31 entries, in the order the page lists them. Built from alzhub.org's own records. % 0 entries have no readable author in the source record and carry no author field. @article{wang2025-40109019, author = {Wang, Lisha and Sooram, Banesh and Kumar, Rajnish and Schedin-Weiss, Sophia and Tjernberg, Lars O and Winblad, Bengt}, title = {{Tau degradation in Alzheimer's disease: Mechanisms and therapeutic opportunities}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2025}, doi = {10.1002/alz.70048}, pmid = {40109019}, url = {https://doi.org/10.1002/alz.70048} } @article{ondrejcak2025-40455293, author = {Ondrejcak, Tomas and Hu, Neng-Wei and Coode, Emily and Campbell, Tom and Corbett, Grant T and Doykov, Ivan and Mills, Kevin and Walsh, Dominic M and others}, title = {{Synaptotoxic effects of extracellular tau are mediated by its microtubule-binding region}}, journal = {Acta neuropathologica}, year = {2025}, doi = {10.1007/s00401-025-02897-0}, pmid = {40455293}, url = {https://doi.org/10.1007/s00401-025-02897-0} } @article{hsieh2024-38470006, author = {Hsieh, Yi-Chen and Augur, Zachary M and Arbery, Mason and Ashour, Nancy and Barrett, Katharine and Pearse, Richard V and Tio, Earvin S and Duong, Duc M and others}, title = {{Person-specific differences in ubiquitin-proteasome mediated proteostasis in human neurons}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2024}, doi = {10.1002/alz.13680}, pmid = {38470006}, url = {https://doi.org/10.1002/alz.13680} } @article{zhang2014-25326800, author = {Zhang, Z. and Song, M. and Liu, X. and Kang, S. S. and Kwon, I. S. and Duong, D. M. and Seyfried, N. T. and Hu, W. T. and others}, title = {{Cleavage of tau by asparagine endopeptidase mediates the neurofibrillary pathology in Alzheimer's disease}}, journal = {Nature medicine}, year = {2014}, doi = {10.1038/nm.3700}, pmid = {25326800}, url = {https://doi.org/10.1038/nm.3700} } @article{guo2017-28386764, author = {Guo, Tong and Noble, Wendy and Hanger, Diane P}, title = {{Roles of tau protein in health and disease}}, journal = {Acta neuropathologica}, year = {2017}, doi = {10.1007/s00401-017-1707-9}, pmid = {28386764}, url = {https://doi.org/10.1007/s00401-017-1707-9} } @article{wang2024-38916730, author = {Wang, Zijian and Pan, Jun-Ping and Geng, Jiayuan and Lv, Shijie and Chen, Guisi and Fang, Nian and Zhang, Zheng and Li, Junliang and others}, title = {{Nogo-A Drives Alzheimer's Disease Progression by Inducing Tauopathy Vulnerability}}, journal = {Aging and disease}, year = {2024}, doi = {10.14336/ad.2024.0053}, pmid = {38916730}, url = {https://doi.org/10.14336/ad.2024.0053} } @article{balducci2025-39871396, author = {Balducci, Claudia and Orsini, Franca and Cerovic, Milica and Beeg, Marten and Rocutto, Beatrice and Dacomo, Letizia and Masone, Antonio and Busani, Eleonora and others}, title = {{Tau oligomers impair memory and synaptic plasticity through the cellular prion protein}}, journal = {Acta neuropathologica communications}, year = {2025}, doi = {10.1186/s40478-025-01930-3}, pmid = {39871396}, url = {https://doi.org/10.1186/s40478-025-01930-3} } @article{tangavelou2024-39596399, author = {Tangavelou, Karthikeyan and Bhaskar, Kiran}, title = {{The Mechanistic Link Between Tau-Driven Proteotoxic Stress and Cellular Senescence in Alzheimer's Disease}}, journal = {International journal of molecular sciences}, year = {2024}, doi = {10.3390/ijms252212335}, pmid = {39596399}, url = {https://doi.org/10.3390/ijms252212335} } @article{chinnathambi2025-40973404, author = {Chinnathambi, Subashchandrabose}, title = {{Tau proteotasis in Alzheimer's disease}}, journal = {Advances in protein chemistry and structural biology}, year = {2025}, doi = {10.1016/bs.apcsb.2024.09.003}, pmid = {40973404}, url = {https://doi.org/10.1016/bs.apcsb.2024.09.003} } @article{waldherr2024-39060347, author = {Waldherr, Sarah M and Han, Marina and Saxton, Aleen D and Vadset, Taylor A and McMillan, Pamela J and Wheeler, Jeanna M and Liachko, Nicole F and Kraemer, Brian C}, title = {{Endoplasmic reticulum unfolded protein response transcriptional targets of XBP-1s mediate rescue from tauopathy}}, journal = {Communications biology}, year = {2024}, doi = {10.1038/s42003-024-06570-2}, pmid = {39060347}, url = {https://doi.org/10.1038/s42003-024-06570-2} } @article{robbins2021-34503576, author = {Robbins, Miranda and Clayton, Emma and Schierle, Gabriele S Kaminski}, title = {{Synaptic tau: A pathological or physiological phenomenon?}}, journal = {Acta neuropathologica communications}, year = {2021}, doi = {10.1186/s40478-021-01246-y}, pmid = {34503576}, url = {https://doi.org/10.1186/s40478-021-01246-y} } @article{wu2021-34753506, author = {Wu, Moxin and Zhang, Manqing and Yin, Xiaoping and Chen, Kai and Hu, Zhijian and Zhou, Qin and Cao, Xianming and Chen, Zhiying and others}, title = {{The role of pathological tau in synaptic dysfunction in Alzheimer's diseases}}, journal = {Translational neurodegeneration}, year = {2021}, doi = {10.1186/s40035-021-00270-1}, pmid = {34753506}, url = {https://doi.org/10.1186/s40035-021-00270-1} } @article{tapiamonsalves2023-37182572, author = {Tapia-Monsalves, Carola and Olesen, Margrethe A and Villavicencio-Tejo, Francisca and Quintanilla, Rodrigo A}, title = {{Cyclosporine A (CsA) prevents synaptic impairment caused by truncated tau by caspase-3}}, journal = {Molecular and cellular neurosciences}, year = {2023}, doi = {10.1016/j.mcn.2023.103861}, pmid = {37182572}, url = {https://doi.org/10.1016/j.mcn.2023.103861} } @article{weng2021-33422896, author = {Weng, Fang-Lin and He, Ling}, title = {{Disrupted ubiquitin proteasome system underlying tau accumulation in Alzheimer's disease}}, journal = {Neurobiology of aging}, year = {2021}, doi = {10.1016/j.neurobiolaging.2020.11.015}, pmid = {33422896}, url = {https://doi.org/10.1016/j.neurobiolaging.2020.11.015} } @article{lasagnareeves2011-21645391, author = {Lasagna-Reeves, C. A. and Castillo-Carranza, D. L. and Sengupta, U. and Clos, A. L. and Jackson, G. R. and Kayed, R.}, title = {{Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice}}, journal = {Molecular neurodegeneration}, year = {2011}, doi = {10.1186/1750-1326-6-39}, pmid = {21645391}, url = {https://doi.org/10.1186/1750-1326-6-39} } @article{lasagnareeves2012-23050084, author = {Lasagna-Reeves, C. A. and Castillo-Carranza, D. L. and Sengupta, U. and Guerrero-Munoz, M. J. and Kiritoshi, T. and Neugebauer, V. and Jackson, G. R. and Kayed, R.}, title = {{Alzheimer brain-derived tau oligomers propagate pathology from endogenous tau}}, journal = {Scientific reports}, year = {2012}, doi = {10.1038/srep00700}, pmid = {23050084}, url = {https://doi.org/10.1038/srep00700} } @article{ebneth1998-9813097, author = {Ebneth, A. and Godemann, R. and Stamer, K. and Illenberger, S. and Trinczek, B. and Mandelkow, E.}, title = {{Overexpression of tau protein inhibits kinesin-dependent trafficking of vesicles, mitochondria, and endoplasmic reticulum: implications for Alzheimer's disease}}, journal = {The Journal of cell biology}, year = {1998}, doi = {10.1083/jcb.143.3.777}, pmid = {9813097}, url = {https://doi.org/10.1083/jcb.143.3.777} } @article{agholme2010-20413890, author = {Agholme, Lotta and Lindström, Tobias and Kågedal, Katarina and Marcusson, Jan O. and Hallbeck, Martin}, title = {{An In Vitro Model for Neuroscience: Differentiation of SH-SY5Y Cells into Cells with Morphological and Biochemical Characteristics of Mature Neurons}}, journal = {Journal of Alzheimer s Disease}, year = {2010}, doi = {10.3233/jad-2010-091363}, pmid = {20413890}, url = {https://doi.org/10.3233/jad-2010-091363} } @article{schindowski2006-16877359, author = {Schindowski, Katharina and Bretteville, Alexis and Leroy, Karelle and Bégard, Séverine and Brion, Jean‐Pierre and Hamdane, Malika and Buée, Luc}, title = {{Alzheimer's Disease-Like Tau Neuropathology Leads to Memory Deficits and Loss of Functional Synapses in a Novel Mutated Tau Transgenic Mouse without Any Motor Deficits}}, journal = {American Journal Of Pathology}, year = {2006}, doi = {10.2353/ajpath.2006.060002}, pmid = {16877359}, url = {https://doi.org/10.2353/ajpath.2006.060002} } @article{jackson2017-28355559, author = {Jackson, Johanna S and Witton, Jonathan and Johnson, James D and Ahmed, Zeshan and Ward, Mark and Randall, Andrew D and Hutton, Michael L and Isaac, John T and others}, title = {{Altered Synapse Stability in the Early Stages of Tauopathy}}, journal = {Cell reports}, year = {2017}, doi = {10.1016/j.celrep.2017.03.013}, pmid = {28355559}, url = {https://doi.org/10.1016/j.celrep.2017.03.013} } @article{pragati2020-31715291, author = {Pragati and Chanu, Soram Idiyasan and Sarkar, Surajit}, title = {{Reduced expression of dMyc mitigates TauV337M mediated neurotoxicity by preventing the Tau hyperphosphorylation and inducing autophagy in Drosophila}}, journal = {Neuroscience letters}, year = {2020}, doi = {10.1016/j.neulet.2019.134622}, pmid = {31715291}, url = {https://doi.org/10.1016/j.neulet.2019.134622} } @article{papanikolopoulou2020-32274757, author = {Papanikolopoulou, Katerina and Skoulakis, Efthimios M C}, title = {{Altered Proteostasis in Neurodegenerative Tauopathies}}, journal = {Advances in experimental medicine and biology}, year = {2020}, doi = {10.1007/978-3-030-38266-7_7}, pmid = {32274757}, url = {https://doi.org/10.1007/978-3-030-38266-7_7} } @article{rajmohan2017-27567878, author = {Rajmohan, R. and Reddy, P. H.}, title = {{Amyloid-Beta and Phosphorylated Tau Accumulations Cause Abnormalities at Synapses of Alzheimer's disease Neurons}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2017}, doi = {10.3233/jad-160612}, pmid = {27567878}, url = {https://doi.org/10.3233/jad-160612} } @article{spiresjones2014-24853936, author = {Spires-Jones, T. L. and Hyman, B. T.}, title = {{The intersection of amyloid beta and tau at synapses in Alzheimer's disease}}, journal = {Neuron}, year = {2014}, doi = {10.1016/j.neuron.2014.05.004}, pmid = {24853936}, url = {https://doi.org/10.1016/j.neuron.2014.05.004} } @article{hoover2010-21172610, author = {Hoover, B. R. and Reed, M. N. and Su, J. and Penrod, R. D. and Kotilinek, L. A. and Grant, M. K. and Pitstick, R. and Carlson, G. A. and others}, title = {{Tau mislocalization to dendritic spines mediates synaptic dysfunction independently of neurodegeneration}}, journal = {Neuron}, year = {2010}, doi = {10.1016/j.neuron.2010.11.030}, pmid = {21172610}, url = {https://doi.org/10.1016/j.neuron.2010.11.030} } @article{arendt2016-27615390, author = {Arendt, T. and Stieler, J. T. and Holzer, M.}, title = {{Tau and tauopathies}}, journal = {Brain research bulletin}, year = {2016}, doi = {10.1016/j.brainresbull.2016.08.018}, pmid = {27615390}, url = {https://doi.org/10.1016/j.brainresbull.2016.08.018} } @article{mandelkow2012-22762014, author = {Mandelkow, E. M. and Mandelkow, E.}, title = {{Biochemistry and cell biology of tau protein in neurofibrillary degeneration}}, journal = {Cold Spring Harbor perspectives in medicine}, year = {2012}, doi = {10.1101/cshperspect.a006247}, pmid = {22762014}, url = {https://doi.org/10.1101/cshperspect.a006247} } @article{zempel2010-20826658, author = {Zempel, H. and Thies, E. and Mandelkow, E. and Mandelkow, E. M.}, title = {{Abeta oligomers cause localized Ca(2+) elevation, missorting of endogenous Tau into dendrites, Tau phosphorylation, and destruction of microtubules and spines}}, journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience}, year = {2010}, doi = {10.1523/jneurosci.2357-10.2010}, pmid = {20826658}, url = {https://doi.org/10.1523/jneurosci.2357-10.2010} } @article{mcdade2024-39108475, author = {McDade, Eric and Liu, Haiyan and Bui, Quoc and Hassenstab, Jason and Gordon, Brian and Benzinger, Tammie and Shen, Yuanyuan and Timsina, Jigyasha and others}, title = {{Ubiquitin-Proteasome System in the Different Stages of Dominantly Inherited Alzheimer's Disease}}, journal = {Research square}, year = {2024}, doi = {10.21203/rs.3.rs-4202125/v1}, pmid = {39108475}, url = {https://doi.org/10.21203/rs.3.rs-4202125/v1} } @article{sun2026-f4157059, author = {Sun, M. N. and Vaughey, K. and Liu, B. and Guo, H. and Huganir, R. and Morris, M.}, title = {{Neuronal Hyperactivity Induces Tau Phosphorylation Selectively in Excitatory Pyramidal Neurons Which Contributes to GluA2 Regulation}}, journal = {bioRxiv}, year = {2026}, doi = {10.64898/2026.10.26.762028}, url = {https://doi.org/10.64898/2026.10.26.762028} } @article{makhlouf2026-4949dd36, author = {Makhlouf, H. and Dorigatti, A. O. and Hernandez, S. and de Rosa, N. and Miller, L. and Hussong, S. and Holstein, D. and Lechleiter, J. and others}, title = {{Soluble pathogenic tau transmission to astrocytes drives cellular senescence and neurovascular uncoupling in a model of Alzheimer’s tauopathy}}, journal = {bioRxiv}, year = {2026}, doi = {10.64898/2026.09.08.750215}, url = {https://doi.org/10.64898/2026.09.08.750215} }