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% Source: https://alzhub.org/research?category=mechanisms&atag=efficacy
% 21 entries, in the order the page lists them. Built from alzhub.org's own records.
% 0 entries have no readable author in the source record and carry no author field.

@article{prins2021-34044875,
  author  = {Prins, N. D. and Harrison, J. E. and Chu, H. M. and Blackburn, K. and Alam, J. J. and Scheltens, P. and {REVERSE-SD Study Investigators}},
  title   = {{A phase 2 double-blind placebo-controlled 24-week treatment clinical study of the p38 alpha kinase inhibitor neflamapimod in mild Alzheimer's disease}},
  journal = {Alzheimer's research \& therapy},
  year    = {2021},
  doi     = {10.1186/s13195-021-00843-2},
  pmid    = {34044875},
  url     = {https://doi.org/10.1186/s13195-021-00843-2}
}

@article{scheltens2018-30309389,
  author  = {Scheltens, P. and Hallikainen, M. and Grimmer, T. and Duning, T. and Gouw, A. A. and Teunissen, C. E. and Wink, A. M. and Maruff, P. and others},
  title   = {{Safety, tolerability and efficacy of the glutaminyl cyclase inhibitor PQ912 in Alzheimer's disease: results of a randomized, double-blind, placebo-controlled phase 2a study}},
  journal = {Alzheimer's research \& therapy},
  year    = {2018},
  doi     = {10.1186/s13195-018-0431-6},
  pmid    = {30309389},
  url     = {https://doi.org/10.1186/s13195-018-0431-6}
}

@article{gibson2020-33074237,
  author  = {Gibson, G. E. and Luchsinger, J. A. and Cirio, R. and Chen, H. and Franchino-Elder, J. and Hirsch, J. A. and Bettendorff, L. and Chen, Z. and others},
  title   = {{Benfotiamine and Cognitive Decline in Alzheimer's Disease: Results of a Randomized Placebo-Controlled Phase IIa Clinical Trial}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2020},
  doi     = {10.3233/jad-200896},
  pmid    = {33074237},
  url     = {https://doi.org/10.3233/jad-200896}
}

@article{pardini2015-25592742,
  author  = {Pardini, M. and Serrati, C. and Guida, S. and Mattei, C. and Abate, L. and Massucco, D. and Sassos, D. and Amore, M. and others},
  title   = {{Souvenaid reduces behavioral deficits and improves social cognition skills in frontotemporal dementia: a proof-of-concept study}},
  journal = {Neuro-degenerative diseases},
  year    = {2015},
  doi     = {10.1159/000369811},
  pmid    = {25592742},
  url     = {https://doi.org/10.1159/000369811}
}

@article{kehinde2025-40725274,
  author  = {Kehinde, S. A. and Lin, W. P. and Lay, B. B. and Phyo, K. Y. and San, M. M. and Pattanayaiying, R. and Chusri, S.},
  title   = {{Curcumin and Dementia: A Systematic Review of Its Effects on Oxidative Stress and Cognitive Outcomes in Animal Models}},
  journal = {International journal of molecular sciences},
  year    = {2025},
  doi     = {10.3390/ijms26147026},
  pmid    = {40725274},
  url     = {https://doi.org/10.3390/ijms26147026}
}

@article{elbakly2019-31163203,
  author  = {El-Bakly, W. and Wagdy, O. and Sobhy, A. and Abo Elenain, O. and Riad, M. S. and El Sayed, M. and Tarkhan, S. and Yassen, M. and others},
  title   = {{The efficacy and underlying mechanism of phosphodiesterase- 5 inhibitors in preventing cognitive impairment and Alzheimer pathology: A systematic review of animal studies}},
  journal = {Behavioural brain research},
  year    = {2019},
  doi     = {10.1016/j.bbr.2019.112004},
  pmid    = {31163203},
  url     = {https://doi.org/10.1016/j.bbr.2019.112004}
}

@article{bhogal2025-40404684,
  author  = {Bhogal, Inderjeet and Pankaj, Vaishali and Roy, Sudeep},
  title   = {{Identifying RAGE inhibitors as potential therapeutics for Alzheimer’s disease via integrated in-silico approaches}},
  journal = {Scientific Reports},
  year    = {2025},
  doi     = {10.1038/s41598-025-01271-0},
  pmid    = {40404684},
  url     = {https://doi.org/10.1038/s41598-025-01271-0}
}

@article{yang2022-35265207,
  author  = {Yang, L. and Wu, C. and Parker, E. and Li, Y. and Dong, Y. and Tucker, L. and Brann, D. W. and Lin, H. W. and others},
  title   = {{Non-invasive photobiomodulation treatment in an Alzheimer Disease-like transgenic rat model}},
  journal = {Theranostics},
  year    = {2022},
  doi     = {10.7150/thno.70756},
  pmid    = {35265207},
  url     = {https://doi.org/10.7150/thno.70756}
}

@article{alsubaie2022-36291224,
  author  = {Alsubaie, N. and Al-Kuraishy, H. M. and Al-Gareeb, A. I. and Alharbi, B. and De Waard, M. and Sabatier, J. M. and Saad, H. M. and Batiha, G. E.},
  title   = {{Statins Use in Alzheimer Disease: Bane or Boon from Frantic Search and Narrative Review}},
  journal = {Brain sciences},
  year    = {2022},
  doi     = {10.3390/brainsci12101290},
  pmid    = {36291224},
  url     = {https://doi.org/10.3390/brainsci12101290}
}

@article{shami2026-40990233,
  author  = {Shami, R. and El Majzoub, R. and Ismail, A. and Kotaich, J. and Kassem, M. and Safadieh, G. and Fayyad-Kazan, M. and Chahine, B.},
  title   = {{Effects of triptolide herb on the progression of Alzheimer's disease preclinical models: a systematic review}},
  journal = {Neurodegenerative disease management},
  year    = {2026},
  doi     = {10.1080/17582024.2025.2562776},
  pmid    = {40990233},
  url     = {https://doi.org/10.1080/17582024.2025.2562776}
}

@article{jia2019-31801553,
  author  = {Jia, L. and Piña-Crespo, J. and Li, Y.},
  title   = {{Restoring Wnt/β-catenin signaling is a promising therapeutic strategy for Alzheimer's disease}},
  journal = {Molecular brain},
  year    = {2019},
  doi     = {10.1186/s13041-019-0525-5},
  pmid    = {31801553},
  url     = {https://doi.org/10.1186/s13041-019-0525-5}
}

@article{lee2020-32714142,
  author  = {Lee, Y. F. and Gerashchenko, D. and Timofeev, I. and Bacskai, B. J. and Kastanenka, K. V.},
  title   = {{Slow Wave Sleep Is a Promising Intervention Target for Alzheimer's Disease}},
  journal = {Frontiers in neuroscience},
  year    = {2020},
  doi     = {10.3389/fnins.2020.00705},
  pmid    = {32714142},
  url     = {https://doi.org/10.3389/fnins.2020.00705}
}

@article{paula2019-31226738,
  author  = {Paula, P. C. and Angelica Maria, S. G. and Luis, C. H. and Gloria Patricia, C. G.},
  title   = {{Preventive Effect of Quercetin in a Triple Transgenic Alzheimer's Disease Mice Model}},
  journal = {Molecules (Basel, Switzerland)},
  year    = {2019},
  doi     = {10.3390/molecules24122287},
  pmid    = {31226738},
  url     = {https://doi.org/10.3390/molecules24122287}
}

@article{zoatier2025-41047159,
  author  = {Zoatier, Bayan and Yildiztekin, Gizem and Alagöz, Mehmet Abdullah and Hepokur, Ceylan and Dilek, Esra and Algül, Öztekin},
  title   = {{Benzoxazole Derivatives as Dual p38α Mitogen‐Activated Protein Kinase and Acetylcholinesterase Inhibitors: Design, Synthesis, and Evaluation for Alzheimer's Disease and Cancer Therapy}},
  journal = {ChemMedChem},
  year    = {2025},
  doi     = {10.1002/cmdc.202500669},
  pmid    = {41047159},
  url     = {https://doi.org/10.1002/cmdc.202500669}
}

@article{navamesa2014-24987334,
  author  = {Nava-Mesa, M. O. and Jiménez-Díaz, L. and Yajeya, J. and Navarro-Lopez, J. D.},
  title   = {{GABAergic neurotransmission and new strategies of neuromodulation to compensate synaptic dysfunction in early stages of Alzheimer's disease}},
  journal = {Frontiers in cellular neuroscience},
  year    = {2014},
  doi     = {10.3389/fncel.2014.00167},
  pmid    = {24987334},
  url     = {https://doi.org/10.3389/fncel.2014.00167}
}

@article{sabogalguaqueta2015-25666032,
  author  = {Sabogal-Guáqueta, A. M. and Muñoz-Manco, J. I. and Ramírez-Pineda, JR. and Lamprea-Rodriguez, M. and Osorio, E. and Cardona-Gómez, G. P.},
  title   = {{The flavonoid quercetin ameliorates Alzheimer's disease pathology and protects cognitive and emotional function in aged triple transgenic Alzheimer's disease model mice}},
  journal = {Neuropharmacology},
  year    = {2015},
  doi     = {10.1016/j.neuropharm.2015.01.027},
  pmid    = {25666032},
  url     = {https://doi.org/10.1016/j.neuropharm.2015.01.027}
}

@article{zhang2014-24022672,
  author  = {Zhang, Z. and Liu, X. and Schroeder, J. P. and Chan, C. B. and Song, M. and Yu, S. P. and Weinshenker, D. and Ye, K.},
  title   = {{7,8-dihydroxyflavone prevents synaptic loss and memory deficits in a mouse model of Alzheimer's disease}},
  journal = {Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology},
  year    = {2014},
  doi     = {10.1038/npp.2013.243},
  pmid    = {24022672},
  url     = {https://doi.org/10.1038/npp.2013.243}
}

@article{teich2015-25575647,
  author  = {Teich, A. F. and Nicholls, R. E. and Puzzo, D. and Fiorito, J. and Purgatorio, R. and Fa', M. and Arancio, O.},
  title   = {{Synaptic therapy in Alzheimer's disease: a CREB-centric approach}},
  journal = {Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics},
  year    = {2015},
  doi     = {10.1007/s13311-014-0327-5},
  pmid    = {25575647},
  url     = {https://doi.org/10.1007/s13311-014-0327-5}
}

@article{lanedonovan2015-26152694,
  author  = {Lane-Donovan, C. and Philips, G. T. and Wasser, C. R. and Durakoglugil, M. S. and Masiulis, I. and Upadhaya, A. and Pohlkamp, T. and Coskun, C. and others},
  title   = {{Reelin protects against amyloid β toxicity in vivo}},
  journal = {Science signaling},
  year    = {2015},
  doi     = {10.1126/scisignal.aaa6674},
  pmid    = {26152694},
  url     = {https://doi.org/10.1126/scisignal.aaa6674}
}

@article{liu2014-24468471,
  author  = {Liu, R. and Li, J. Z. and Song, J. K. and Zhou, D. and Huang, C. and Bai, X. Y. and Xie, T. and Zhang, X. and others},
  title   = {{Pinocembrin improves cognition and protects the neurovascular unit in Alzheimer related deficits}},
  journal = {Neurobiology of aging},
  year    = {2014},
  doi     = {10.1016/j.neurobiolaging.2013.12.031},
  pmid    = {24468471},
  url     = {https://doi.org/10.1016/j.neurobiolaging.2013.12.031}
}

@article{gibizov2025-51978b36,
  author  = {Gibizov, Yuriy A. and Вагапова, Л. Ш. and Aguzarova, Alina O. and Nazarova, Julia V. and Zotkina, Yana A. and Atamanyuk, Ekaterina A. and Rodikova, Mariia M. and Timergaleev, Rafael N. and others},
  title   = {{Physical Activity and the Myokine Irisin in Non-pharmacological Treatment of Alzheimer Disease}},
  journal = {Russian Journal of Physiotherapy Balneology and Rehabilitation},
  year    = {2025},
  doi     = {10.17816/rjpbr677844},
  url     = {https://doi.org/10.17816/rjpbr677844}
}