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% Source: https://alzhub.org/research?category=assessment&atag=efficacy
% 53 entries, in the order the page lists them. Built from alzhub.org's own records.
% 0 entries have no readable author in the source record and carry no author field.

@article{florian2023-36730056,
  author  = {Florian, H. and Wang, D. and Arnold, S. E. and Boada, M. and Guo, Q. and Jin, Z. and Zheng, H. and Fisseha, N. and others},
  title   = {{Tilavonemab in early Alzheimer's disease: results from a phase 2, randomized, double-blind study}},
  journal = {Brain : a journal of neurology},
  year    = {2023},
  doi     = {10.1093/brain/awad024},
  pmid    = {36730056},
  url     = {https://doi.org/10.1093/brain/awad024}
}

@article{birks2003-12917900,
  author  = {Birks, J. S. and Harvey, R.},
  title   = {{Donepezil for dementia due to Alzheimer's disease}},
  journal = {The Cochrane database of systematic reviews},
  year    = {2003},
  doi     = {10.1002/14651858.cd001190},
  pmid    = {12917900},
  url     = {https://doi.org/10.1002/14651858.cd001190}
}

@article{birks2000-11034705,
  author  = {Birks, J. and Grimley Evans, J. and Iakovidou, V. and Tsolaki, M.},
  title   = {{Rivastigmine for Alzheimer's disease}},
  journal = {The Cochrane database of systematic reviews},
  year    = {2000},
  doi     = {10.1002/14651858.cd001191},
  pmid    = {11034705},
  url     = {https://doi.org/10.1002/14651858.cd001191}
}

@article{sabbagh2020-31879235,
  author  = {Sabbagh, M. and Sadowsky, C. and Tousi, B. and Agronin, M. E. and Alva, G. and Armon, C. and Bernick, C. and Keegan, A. P. and others},
  title   = {{Effects of a combined transcranial magnetic stimulation (TMS) and cognitive training intervention in patients with Alzheimer's disease}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2020},
  doi     = {10.1016/j.jalz.2019.08.197},
  pmid    = {31879235},
  url     = {https://doi.org/10.1016/j.jalz.2019.08.197}
}

@article{dubois2023-36849969,
  author  = {Dubois, B. and López-Arrieta, J. and Lipschitz, S. and Doskas, T. and Spiru, L. and Moroz, S. and Venger, O. and Vermersch, P. and others},
  title   = {{Masitinib for mild-to-moderate Alzheimer's disease: results from a randomized, placebo-controlled, phase 3, clinical trial}},
  journal = {Alzheimer's research \& therapy},
  year    = {2023},
  doi     = {10.1186/s13195-023-01169-x},
  pmid    = {36849969},
  url     = {https://doi.org/10.1186/s13195-023-01169-x}
}

@article{lawlor2018-30248105,
  author  = {Lawlor, B. and Segurado, R. and Kennelly, S. and Olde Rikkert, M. G. M. and Howard, R. and Pasquier, F. and Börjesson-Hanson, A. and Tsolaki, M. and others},
  title   = {{Nilvadipine in mild to moderate Alzheimer disease: A randomised controlled trial}},
  journal = {PLoS medicine},
  year    = {2018},
  doi     = {10.1371/journal.pmed.1002660},
  pmid    = {30248105},
  url     = {https://doi.org/10.1371/journal.pmed.1002660}
}

@article{anderson2011-20980201,
  author  = {Anderson, C. and Teo, K. and Gao, P. and Arima, H. and Dans, A. and Unger, T. and Commerford, P. and Dyal, L. and others},
  title   = {{Renin-angiotensin system blockade and cognitive function in patients at high risk of cardiovascular disease: analysis of data from the ONTARGET and TRANSCEND studies}},
  journal = {The Lancet. Neurology},
  year    = {2011},
  doi     = {10.1016/s1474-4422(10)70250-7},
  pmid    = {20980201},
  url     = {https://doi.org/10.1016/s1474-4422(10)70250-7}
}

@article{cummings2026-41865758,
  author  = {Cummings, Jeffrey L and Atri, Alireza and Sano, Mary and Zetterberg, Henrik and Scheltens, Philip and Knop, Filip K and Johannsen, Peter and Wichmann, Christian Ahmad and others},
  title   = {{Efficacy and safety of oral semaglutide 14 mg (flexible dose) in early-stage symptomatic Alzheimer's disease (evoke and evoke+): two phase 3, randomised, placebo-controlled trials}},
  journal = {The Lancet},
  year    = {2026},
  doi     = {10.1016/s0140-6736(26)00459-9},
  pmid    = {41865758},
  url     = {https://doi.org/10.1016/s0140-6736(26)00459-9}
}

@article{lozano2016-27567810,
  author  = {Lozano, A. M. and Fosdick, L. and Chakravarty, M. M. and Leoutsakos, J. M. and Munro, C. and Oh, E. and Drake, K. E. and Lyman, C. H. and others},
  title   = {{A Phase II Study of Fornix Deep Brain Stimulation in Mild Alzheimer's Disease}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2016},
  doi     = {10.3233/jad-160017},
  pmid    = {27567810},
  url     = {https://doi.org/10.3233/jad-160017}
}

@article{boada2020-32715623,
  author  = {Boada, M. and López, O. L. and Olazarán, J. and Núñez, L. and Pfeffer, M. and Paricio, M. and Lorites, J. and Piñol-Ripoll, G. and others},
  title   = {{A randomized, controlled clinical trial of plasma exchange with albumin replacement for Alzheimer's disease: Primary results of the AMBAR Study}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2020},
  doi     = {10.1002/alz.12137},
  pmid    = {32715623},
  url     = {https://doi.org/10.1002/alz.12137}
}

@article{wilcock2008-18450517,
  author  = {Wilcock, G. K. and Black, S. E. and Hendrix, S. B. and Zavitz, K. H. and Swabb, E. A. and Laughlin, M. A. and {Tarenflurbil Phase II Study investigators}},
  title   = {{Efficacy and safety of tarenflurbil in mild to moderate Alzheimer's disease: a randomised phase II trial}},
  journal = {The Lancet. Neurology},
  year    = {2008},
  doi     = {10.1016/s1474-4422(08)70090-5},
  pmid    = {18450517},
  url     = {https://doi.org/10.1016/s1474-4422(08)70090-5}
}

@article{gauthier2009-19536424,
  author  = {Gauthier, S. and Aisen, P. S. and Ferris, S. H. and Saumier, D. and Duong, A. and Haine, D. and Garceau, D. and Suhy, J. and others},
  title   = {{Effect of tramiprosate in patients with mild-to-moderate Alzheimer's disease: exploratory analyses of the MRI sub-group of the Alphase study}},
  journal = {The journal of nutrition, health \& aging},
  year    = {2009},
  doi     = {10.1007/s12603-009-0106-x},
  pmid    = {19536424},
  url     = {https://doi.org/10.1007/s12603-009-0106-x}
}

@article{rosenberg2013-24021498,
  author  = {Rosenberg, P. B. and Lanctôt, K. L. and Drye, L. T. and Herrmann, N. and Scherer, R. W. and Bachman, D. L. and Mintzer, J. E. and {ADMET Investigators}},
  title   = {{Safety and efficacy of methylphenidate for apathy in Alzheimer's disease: a randomized, placebo-controlled trial}},
  journal = {The Journal of clinical psychiatry},
  year    = {2013},
  doi     = {10.4088/jcp.12m08099},
  pmid    = {24021498},
  url     = {https://doi.org/10.4088/jcp.12m08099}
}

@article{yang2013-24086396,
  author  = {Yang, G. and Wang, Y. and Tian, J. and Liu, J. P.},
  title   = {{Huperzine A for Alzheimer's disease: a systematic review and meta-analysis of randomized clinical trials}},
  journal = {PloS one},
  year    = {2013},
  doi     = {10.1371/journal.pone.0074916},
  pmid    = {24086396},
  url     = {https://doi.org/10.1371/journal.pone.0074916}
}

@article{jia2017-29284465,
  author  = {Jia, Y. and Zhang, X. and Yu, J. and Han, J. and Yu, T. and Shi, J. and Zhao, L. and Nie, K.},
  title   = {{Acupuncture for patients with mild to moderate Alzheimer's disease: a randomized controlled trial}},
  journal = {BMC complementary and alternative medicine},
  year    = {2017},
  doi     = {10.1186/s12906-017-2064-x},
  pmid    = {29284465},
  url     = {https://doi.org/10.1186/s12906-017-2064-x}
}

@article{dejong2008-18213383,
  author  = {de Jong, D. and Jansen, R. and Hoefnagels, W. and Jellesma-Eggenkamp, M. and Verbeek, M. and Borm, G. and Kremer, B.},
  title   = {{No effect of one-year treatment with indomethacin on Alzheimer's disease progression: a randomized controlled trial}},
  journal = {PloS one},
  year    = {2008},
  doi     = {10.1371/journal.pone.0001475},
  pmid    = {18213383},
  url     = {https://doi.org/10.1371/journal.pone.0001475}
}

@article{diener2008-18757238,
  author  = {Diener, H. C. and Sacco, R. L. and Yusuf, S. and Cotton, D. and Ounpuu, S. and Lawton, W. A. and Palesch, Y. and Martin, R. H. and others},
  title   = {{Effects of aspirin plus extended-release dipyridamole versus clopidogrel and telmisartan on disability and cognitive function after recurrent stroke in patients with ischaemic stroke in the Prevention Regimen for Effectively Avoiding Second Strokes (PRoFESS) trial: a double-blind, active and placebo-controlled study}},
  journal = {The Lancet. Neurology},
  year    = {2008},
  doi     = {10.1016/s1474-4422(08)70198-4},
  pmid    = {18757238},
  url     = {https://doi.org/10.1016/s1474-4422(08)70198-4}
}

@article{wang2022-36150665,
  author  = {Wang, L. and Zhang, J. and Guo, C. and He, J. and Zhang, S. and Wang, Y. and Zhao, Y. and Li, L. and others},
  title   = {{The efficacy and safety of transcutaneous auricular vagus nerve stimulation in patients with mild cognitive impairment: A double blinded randomized clinical trial}},
  journal = {Brain stimulation},
  year    = {2022},
  doi     = {10.1016/j.brs.2022.09.003},
  pmid    = {36150665},
  url     = {https://doi.org/10.1016/j.brs.2022.09.003}
}

@article{burstein2014-24423155,
  author  = {Burstein, A. H. and Grimes, I. and Galasko, D. R. and Aisen, P. S. and Sabbagh, M. and Mjalli, A. M.},
  title   = {{Effect of TTP488 in patients with mild to moderate Alzheimer's disease}},
  journal = {BMC neurology},
  year    = {2014},
  doi     = {10.1186/1471-2377-14-12},
  pmid    = {24423155},
  url     = {https://doi.org/10.1186/1471-2377-14-12}
}

@article{freundlevi2008-17582225,
  author  = {Freund-Levi, Y. and Basun, H. and Cederholm, T. and Faxén-Irving, G. and Garlind, A. and Grut, M. and Vedin, I. and Palmblad, J. and others},
  title   = {{Omega-3 supplementation in mild to moderate Alzheimer's disease: effects on neuropsychiatric symptoms}},
  journal = {International journal of geriatric psychiatry},
  year    = {2008},
  doi     = {10.1002/gps.1857},
  pmid    = {17582225},
  url     = {https://doi.org/10.1002/gps.1857}
}

@article{study2008-18068522,
  author  = {{AD2000 Collaborative Group} and Bentham, P. and Gray, R. and Sellwood, E. and Hills, R. and Crome, P. and Raftery, J.},
  title   = {{Aspirin in Alzheimer's disease (AD2000): a randomised open-label trial}},
  journal = {The Lancet. Neurology},
  year    = {2008},
  doi     = {10.1016/s1474-4422(07)70293-4},
  pmid    = {18068522},
  url     = {https://doi.org/10.1016/s1474-4422(07)70293-4}
}

@article{harrington2011-21592048,
  author  = {Harrington, C. and Sawchak, S. and Chiang, C. and Davies, J. and Donovan, C. and Saunders, A. M. and Irizarry, M. and Jeter, B. and others},
  title   = {{Rosiglitazone does not improve cognition or global function when used as adjunctive therapy to AChE inhibitors in mild-to-moderate Alzheimer's disease: two phase 3 studies}},
  journal = {Current Alzheimer research},
  year    = {2011},
  doi     = {10.2174/156720511796391935},
  pmid    = {21592048},
  url     = {https://doi.org/10.2174/156720511796391935}
}

@article{akhondzadeh2003-12810768,
  author  = {Akhondzadeh, S. and Noroozian, M. and Mohammadi, M. and Ohadinia, S. and Jamshidi, A. H. and Khani, M.},
  title   = {{Melissa officinalis extract in the treatment of patients with mild to moderate Alzheimer's disease: a double blind, randomised, placebo controlled trial}},
  journal = {Journal of neurology, neurosurgery, and psychiatry},
  year    = {2003},
  doi     = {10.1136/jnnp.74.7.863},
  pmid    = {12810768},
  url     = {https://doi.org/10.1136/jnnp.74.7.863}
}

@article{otto2004-15007119,
  author  = {Otto, M. and Cepek, L. and Ratzka, P. and Doehlinger, S. and Boekhoff, I. and Wiltfang, J. and Irle, E. and Pergande, G. and others},
  title   = {{Efficacy of flupirtine on cognitive function in patients with CJD: A double-blind study}},
  journal = {Neurology},
  year    = {2004},
  doi     = {10.1212/01.wnl.0000113764.35026.ef},
  pmid    = {15007119},
  url     = {https://doi.org/10.1212/01.wnl.0000113764.35026.ef}
}

@article{stein2011-21694461,
  author  = {Stein, M. S. and Scherer, S. C. and Ladd, K. S. and Harrison, L. C.},
  title   = {{A randomized controlled trial of high-dose vitamin D2 followed by intranasal insulin in Alzheimer's disease}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2011},
  doi     = {10.3233/jad-2011-110149},
  pmid    = {21694461},
  url     = {https://doi.org/10.3233/jad-2011-110149}
}

@article{iwasaki2005-15705012,
  author  = {Iwasaki, K. and Satoh-Nakagawa, T. and Maruyama, M. and Monma, Y. and Nemoto, M. and Tomita, N. and Tanji, H. and Fujiwara, H. and others},
  title   = {{A randomized, observer-blind, controlled trial of the traditional Chinese medicine Yi-Gan San for improvement of behavioral and psychological symptoms and activities of daily living in dementia patients}},
  journal = {The Journal of clinical psychiatry},
  year    = {2005},
  doi     = {10.4088/jcp.v66n0214},
  pmid    = {15705012},
  url     = {https://doi.org/10.4088/jcp.v66n0214}
}

@article{akhondzadeh2003-12605619,
  author  = {Akhondzadeh, S. and Noroozian, M. and Mohammadi, M. and Ohadinia, S. and Jamshidi, A. H. and Khani, M.},
  title   = {{Salvia officinalis extract in the treatment of patients with mild to moderate Alzheimer's disease: a double blind, randomized and placebo-controlled trial}},
  journal = {Journal of clinical pharmacy and therapeutics},
  year    = {2003},
  doi     = {10.1046/j.1365-2710.2003.00463.x},
  pmid    = {12605619},
  url     = {https://doi.org/10.1046/j.1365-2710.2003.00463.x}
}

@article{akhondzadeh2010-20831681,
  author  = {Akhondzadeh, S. and Sabet, M. S. and Harirchian, M. H. and Togha, M. and Cheraghmakani, H. and Razeghi, S. and SSh, Hejazi and Yousefi, M. H. and others},
  title   = {{Saffron in the treatment of patients with mild to moderate Alzheimer's disease: a 16-week, randomized and placebo-controlled trial}},
  journal = {Journal of clinical pharmacy and therapeutics},
  year    = {2010},
  doi     = {10.1111/j.1365-2710.2009.01133.x},
  pmid    = {20831681},
  url     = {https://doi.org/10.1111/j.1365-2710.2009.01133.x}
}

@article{mizukami2009-19079814,
  author  = {Mizukami, K. and Asada, T. and Kinoshita, T. and Tanaka, K. and Sonohara, K. and Nakai, R. and Yamaguchi, K. and Hanyu, H. and others},
  title   = {{A randomized cross-over study of a traditional Japanese medicine (kampo), yokukansan, in the treatment of the behavioural and psychological symptoms of dementia}},
  journal = {The international journal of neuropsychopharmacology},
  year    = {2009},
  doi     = {10.1017/s146114570800970x},
  pmid    = {19079814},
  url     = {https://doi.org/10.1017/s146114570800970x}
}

@article{heo2008-18684311,
  author  = {Heo, J. H. and Lee, S. T. and Chu, K. and Oh, M. J. and Park, H. J. and Shim, J. Y. and Kim, M.},
  title   = {{An open-label trial of Korean red ginseng as an adjuvant treatment for cognitive impairment in patients with Alzheimer's disease}},
  journal = {European journal of neurology},
  year    = {2008},
  doi     = {10.1111/j.1468-1331.2008.02157.x},
  pmid    = {18684311},
  url     = {https://doi.org/10.1111/j.1468-1331.2008.02157.x}
}

@article{lebars2000-10867450,
  author  = {Le Bars, P. L. and Kieser, M. and Itil, K. Z.},
  title   = {{A 26-week analysis of a double-blind, placebo-controlled trial of the ginkgo biloba extract EGb 761 in dementia}},
  journal = {Dementia and geriatric cognitive disorders},
  year    = {2000},
  doi     = {10.1159/000017242},
  pmid    = {10867450},
  url     = {https://doi.org/10.1159/000017242}
}

@article{miguelalvarez2015-25644018,
  author  = {Miguel-Álvarez, M. and Santos-Lozano, A. and Sanchis-Gomar, F. and Fiuza-Luces, C. and Pareja-Galeano, H. and Garatachea, N. and Lucia, A.},
  title   = {{Non-steroidal anti-inflammatory drugs as a treatment for Alzheimer's disease: a systematic review and meta-analysis of treatment effect}},
  journal = {Drugs \& aging},
  year    = {2015},
  doi     = {10.1007/s40266-015-0239-z},
  pmid    = {25644018},
  url     = {https://doi.org/10.1007/s40266-015-0239-z}
}

@article{abushakra2025-41015981,
  author  = {Abushakra, Susan R. and Power, Aidan and Watson, David and Porsteinsson, Anton P. and Sabbagh, Marwan and MacSweeney, Emer and Cohen, Sharon and Boada, Merçé and others},
  title   = {{Clinical Efficacy, Safety and Imaging Effects of Oral Valiltramiprosate in APOEε4/ε4 Homozygotes with Early Alzheimer’s Disease: Results of the Phase III, Randomized, Double-Blind, Placebo-Controlled, 78-Week APOLLOE4 Trial}},
  journal = {Drugs},
  year    = {2025},
  doi     = {10.1007/s40265-025-02250-5},
  pmid    = {41015981},
  url     = {https://doi.org/10.1007/s40265-025-02250-5}
}

@article{koch2025-40176122,
  author  = {Koch, Giacomo and Casula, Elias Paolo and Bonnı̀, Sonia and Borghi, Ilaria and Assogna, Martina and Di Lorenzo, Francesco and Esposito, Romina and Maiella, Michele and others},
  title   = {{Effects of 52 weeks of precuneus rTMS in Alzheimer’s disease patients: a randomized trial}},
  journal = {Alzheimer s Research \& Therapy},
  year    = {2025},
  doi     = {10.1186/s13195-025-01709-7},
  pmid    = {40176122},
  url     = {https://doi.org/10.1186/s13195-025-01709-7}
}

@article{doraiswamy2014-24614494,
  author  = {Doraiswamy, P. M. and Sperling, R. A. and Johnson, K. and Reiman, E. M. and Wong, T. Z. and Sabbagh, M. N. and Sadowsky, C. H. and Fleisher, A. S. and others},
  title   = {{Florbetapir F 18 amyloid PET and 36-month cognitive decline: a prospective multicenter study}},
  journal = {Molecular psychiatry},
  year    = {2014},
  doi     = {10.1038/mp.2014.9},
  pmid    = {24614494},
  url     = {https://doi.org/10.1038/mp.2014.9}
}

@article{silveira2019-30738426,
  author  = {Silveira, C. R. A. and MacKinley, J. and Coleman, K. and Li, Z. and Finger, E. and Bartha, R. and Morrow, S. A. and Wells, J. and others},
  title   = {{Ambroxol as a novel disease-modifying treatment for Parkinson's disease dementia: protocol for a single-centre, randomized, double-blind, placebo-controlled trial}},
  journal = {BMC neurology},
  year    = {2019},
  doi     = {10.1186/s12883-019-1252-3},
  pmid    = {30738426},
  url     = {https://doi.org/10.1186/s12883-019-1252-3}
}

@article{nygaard2015-25874001,
  author  = {Nygaard, H. B. and Wagner, A. F. and Bowen, G. S. and Good, S. P. and MacAvoy, M. G. and Strittmatter, K. A. and Kaufman, A. C. and Rosenberg, B. J. and others},
  title   = {{A phase Ib multiple ascending dose study of the safety, tolerability, and central nervous system availability of AZD0530 (saracatinib) in Alzheimer's disease}},
  journal = {Alzheimer's research \& therapy},
  year    = {2015},
  doi     = {10.1186/s13195-015-0119-0},
  pmid    = {25874001},
  url     = {https://doi.org/10.1186/s13195-015-0119-0}
}

@article{sankhe2026-41521126,
  author  = {Sankhe, Krushnaa and Ruthirakuhan, Myuri T. and Andreazza, Ana C. and Brawman‐Mintzer, Olga and Craft, Suzanne and Herrmann, Nathan and Ismail, Zahinoor and Lerner, Alan J. and others},
  title   = {{Peripheral biomarkers associated with apathy and predicting response to methylphenidate: Secondary analysis of the Apathy in Dementia Methylphenidate Trial 2 (ADMET2) study}},
  journal = {International Psychogeriatrics},
  year    = {2026},
  doi     = {10.1016/j.inpsyc.2025.100181},
  pmid    = {41521126},
  url     = {https://doi.org/10.1016/j.inpsyc.2025.100181}
}

@article{hager2007-17982894,
  author  = {Hager, K. and Kenklies, M. and McAfoose, J. and Engel, J. and Münch, G.},
  title   = {{Alpha-lipoic acid as a new treatment option for Alzheimer's disease--a 48 months follow-up analysis}},
  journal = {Journal of neural transmission. Supplementum},
  year    = {2007},
  doi     = {10.1007/978-3-211-73574-9_24},
  pmid    = {17982894},
  url     = {https://doi.org/10.1007/978-3-211-73574-9_24}
}

@article{maczurek2008-18655815,
  author  = {Maczurek, A. and Hager, K. and Kenklies, M. and Sharman, M. and Martins, R. and Engel, J. and Carlson, D. A. and Münch, G.},
  title   = {{Lipoic acid as an anti-inflammatory and neuroprotective treatment for Alzheimer's disease}},
  journal = {Advanced drug delivery reviews},
  year    = {2008},
  doi     = {10.1016/j.addr.2008.04.015},
  pmid    = {18655815},
  url     = {https://doi.org/10.1016/j.addr.2008.04.015}
}

@article{saltmarche2017-28186867,
  author  = {Saltmarche, A. E. and Naeser, M. A. and Ho, K. F. and Hamblin, M. R. and Lim, L.},
  title   = {{Significant Improvement in Cognition in Mild to Moderately Severe Dementia Cases Treated with Transcranial Plus Intranasal Photobiomodulation: Case Series Report}},
  journal = {Photomedicine and laser surgery},
  year    = {2017},
  doi     = {10.1089/pho.2016.4227},
  pmid    = {28186867},
  url     = {https://doi.org/10.1089/pho.2016.4227}
}

@article{kountouras2009-19240960,
  author  = {Kountouras, J. and Boziki, M. and Gavalas, E. and Zavos, C. and Grigoriadis, N. and Deretzi, G. and Tzilves, D. and Katsinelos, P. and others},
  title   = {{Eradication of Helicobacter pylori may be beneficial in the management of Alzheimer's disease}},
  journal = {Journal of neurology},
  year    = {2009},
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