% alzhub.org library filter
% Source: https://alzhub.org/research?atag=dosage
% 80 entries, in the order the page lists them. Built from alzhub.org's own records.
% 0 entries have no readable author in the source record and carry no author field.

@article{handen2020-32775597,
  author  = {Handen, B. L. and Lott, I. T. and Christian, B. T. and Schupf, N. and OBryant, S. and Mapstone, M. and Fagan, A. M. and Lee, J. H. and others},
  title   = {{The Alzheimer's Biomarker Consortium-Down Syndrome: Rationale and methodology}},
  journal = {Alzheimer's \& dementia (Amsterdam, Netherlands)},
  year    = {2020},
  doi     = {10.1002/dad2.12065},
  pmid    = {32775597},
  url     = {https://doi.org/10.1002/dad2.12065}
}

@article{iulita2023-37056479,
  author  = {Iulita, M. F. and Bejanin, A. and Vilaplana, E. and Carmona-Iragui, M. and Benejam, B. and Videla, L. and Barroeta, I. and Fernández, S. and others},
  title   = {{Association of biological sex with clinical outcomes and biomarkers of Alzheimer's disease in adults with Down syndrome}},
  journal = {Brain communications},
  year    = {2023},
  doi     = {10.1093/braincomms/fcad074},
  pmid    = {37056479},
  url     = {https://doi.org/10.1093/braincomms/fcad074}
}

@article{strydom2018-29631614,
  author  = {Strydom, A. and Heslegrave, A. and Startin, C. M. and Mok, K. Y. and Hardy, J. and Groet, J. and Nizetic, D. and Zetterberg, H. and others},
  title   = {{Neurofilament light as a blood biomarker for neurodegeneration in Down syndrome}},
  journal = {Alzheimer's research \& therapy},
  year    = {2018},
  doi     = {10.1186/s13195-018-0367-x},
  pmid    = {29631614},
  url     = {https://doi.org/10.1186/s13195-018-0367-x}
}

@article{rowe2006-16480563,
  author  = {Rowe, J. and Lavender, A. and Turk, V.},
  title   = {{Cognitive executive function in Down's syndrome}},
  journal = {The British journal of clinical psychology},
  year    = {2006},
  doi     = {10.1348/014466505x29594},
  pmid    = {16480563},
  url     = {https://doi.org/10.1348/014466505x29594}
}

@article{csincsik2021-33748396,
  author  = {Csincsik, Lajos and Nelson, Rachel and Walpert, Madeleine J and Peto, Tunde and Holland, Anthony and Lengyel, Imre},
  title   = {{Increased choroidal thickness in adults with Down syndrome}},
  journal = {Alzheimer's \& dementia (Amsterdam, Netherlands)},
  year    = {2021},
  doi     = {10.1002/dad2.12170},
  pmid    = {33748396},
  url     = {https://doi.org/10.1002/dad2.12170}
}

@article{baksh2023-37119823,
  author  = {Baksh, R. A. and Pape, S. E. and Chan, L. F. and Aslam, A. A. and Gulliford, M. C. and Strydom, A. and {GO-DS21 Consortium}},
  title   = {{Multiple morbidity across the lifespan in people with Down syndrome or intellectual disabilities: a population-based cohort study using electronic health records}},
  journal = {The Lancet. Public health},
  year    = {2023},
  doi     = {10.1016/s2468-2667(23)00057-9},
  pmid    = {37119823},
  url     = {https://doi.org/10.1016/s2468-2667(23)00057-9}
}

@article{glasson2014-23510031,
  author  = {Glasson, E. J. and Dye, D. E. and Bittles, A. H.},
  title   = {{The triple challenges associated with age-related comorbidities in Down syndrome}},
  journal = {Journal of intellectual disability research : JIDR},
  year    = {2014},
  doi     = {10.1111/jir.12026},
  pmid    = {23510031},
  url     = {https://doi.org/10.1111/jir.12026}
}

@article{hartley2015-25510383,
  author  = {Hartley, D. and Blumenthal, T. and Carrillo, M. and DiPaolo, G. and Esralew, L. and Gardiner, K. and Granholm, A. C. and Iqbal, K. and others},
  title   = {{Down syndrome and Alzheimer's disease: Common pathways, common goals}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2015},
  doi     = {10.1016/j.jalz.2014.10.007},
  pmid    = {25510383},
  url     = {https://doi.org/10.1016/j.jalz.2014.10.007}
}

@article{zigman2013-23949829,
  author  = {Zigman, W. B.},
  title   = {{Atypical aging in Down syndrome}},
  journal = {Developmental disabilities research reviews},
  year    = {2013},
  doi     = {10.1002/ddrr.1128},
  pmid    = {23949829},
  url     = {https://doi.org/10.1002/ddrr.1128}
}

@article{fleming2023-36565120,
  author  = {Fleming, Victoria and Helsel, Brian C and Ptomey, Lauren T and Rosas, H Diana and Handen, Benjamin and Laymon, Charles and Christian, Bradley T and Head, Elizabeth and others},
  title   = {{Weight Loss and Alzheimer's Disease in Down Syndrome}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2023},
  doi     = {10.3233/jad-220865},
  pmid    = {36565120},
  url     = {https://doi.org/10.3233/jad-220865}
}

@article{cole2017-28482213,
  author  = {Cole, J. H. and Annus, T. and Wilson, L. R. and Remtulla, R. and Hong, Y. T. and Fryer, T. D. and Acosta-Cabronero, J. and Cardenas-Blanco, A. and others},
  title   = {{Brain-predicted age in Down syndrome is associated with beta amyloid deposition and cognitive decline}},
  journal = {Neurobiology of aging},
  year    = {2017},
  doi     = {10.1016/j.neurobiolaging.2017.04.006},
  pmid    = {28482213},
  url     = {https://doi.org/10.1016/j.neurobiolaging.2017.04.006}
}

@article{davidson2018-29973279,
  author  = {Davidson, Y. S. and Robinson, A. and Prasher, V. P. and Mann, D. M. A.},
  title   = {{The age of onset and evolution of Braak tangle stage and Thal amyloid pathology of Alzheimer's disease in individuals with Down syndrome}},
  journal = {Acta neuropathologica communications},
  year    = {2018},
  doi     = {10.1186/s40478-018-0559-4},
  pmid    = {29973279},
  url     = {https://doi.org/10.1186/s40478-018-0559-4}
}

@article{floresaguilar2020-33206953,
  author  = {Flores-Aguilar, L. and Iulita, M. F. and Kovecses, O. and Torres, M. D. and Levi, S. M. and Zhang, Y. and Askenazi, M. and Wisniewski, T. and others},
  title   = {{Evolution of neuroinflammation across the lifespan of individuals with Down syndrome}},
  journal = {Brain : a journal of neurology},
  year    = {2020},
  doi     = {10.1093/brain/awaa326},
  pmid    = {33206953},
  url     = {https://doi.org/10.1093/brain/awaa326}
}

@article{myers1991-1833506,
  author  = {Myers, B. A. and Pueschel, S. M.},
  title   = {{Psychiatric disorders in persons with Down syndrome}},
  journal = {The Journal of nervous and mental disease},
  year    = {1991},
  doi     = {10.1097/00005053-199110000-00004},
  pmid    = {1833506},
  url     = {https://doi.org/10.1097/00005053-199110000-00004}
}

@article{palmer2021-34795060,
  author  = {Palmer, Carter R and Liu, Christine S and Romanow, William J and Lee, Ming-Hsiang and Chun, Jerold},
  title   = {{Altered cell and RNA isoform diversity in aging Down syndrome brains}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {2021},
  doi     = {10.1073/pnas.2114326118},
  pmid    = {34795060},
  url     = {https://doi.org/10.1073/pnas.2114326118}
}

@article{dunn2025-82cc99de,
  author  = {Dunn, L. N. and Niemeyer, B. F. and Eduthan, N. P. and Schade, K. A. and Waugh, K. A. and Brown, C. and Rachubinski, A. L. and Timkovich, A. E. and others},
  title   = {{Altered Hepatic Metabolism in Down Syndrome}},
  journal = {Cell reports},
  year    = {2025},
  doi     = {10.1101/2025.05.27.656393},
  url     = {https://doi.org/10.1101/2025.05.27.656393}
}

@article{wiseman2018-29945247,
  author  = {Wiseman, F. K. and Pulford, L. J. and Barkus, C. and Liao, F. and Portelius, E. and Webb, R. and Chávez-Gutiérrez, L. and Cleverley, K. and others},
  title   = {{Trisomy of human chromosome 21 enhances amyloid-β deposition independently of an extra copy of APP}},
  journal = {Brain : a journal of neurology},
  year    = {2018},
  doi     = {10.1093/brain/awy159},
  pmid    = {29945247},
  url     = {https://doi.org/10.1093/brain/awy159}
}

@article{goffinski2015-c6aa376b,
  author  = {Goffinski, Alida and Stanley, Maria A. and Shepherd, Nicole and Duvall, Nichole and Jenkinson, Sandra B. and Davis, Charlene and Bull, Marilyn J. and Roper, Randall J.},
  title   = {{Obstructive sleep apnea in young infants with Down Syndrome evaluated in a Down Syndrome specialty clinic}},
  journal = {American Journal of Medical Genetics Part A},
  year    = {2015},
  doi     = {10.1002/ajmg.a.36903},
  url     = {https://doi.org/10.1002/ajmg.a.36903}
}

@article{mann1989-2522541,
  author  = {Mann, D. M. and Esiri, M. M.},
  title   = {{The pattern of acquisition of plaques and tangles in the brains of patients under 50 years of age with Down's syndrome}},
  journal = {Journal of the neurological sciences},
  year    = {1989},
  doi     = {10.1016/0022-510x(89)90019-1},
  pmid    = {2522541},
  url     = {https://doi.org/10.1016/0022-510x(89)90019-1}
}

@article{doran2017-27983553,
  author  = {Doran, E. and Keator, D. and Head, E. and Phelan, M. J. and Kim, R. and Totoiu, M. and Barrio, JR. and Small, G. W. and others},
  title   = {{Down Syndrome, Partial Trisomy 21, and Absence of Alzheimer's Disease: The Role of APP}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2017},
  doi     = {10.3233/jad-160836},
  pmid    = {27983553},
  url     = {https://doi.org/10.3233/jad-160836}
}

@article{kim2016-26194181,
  author  = {Kim, S. and Sato, Y. and Mohan, P. S. and Peterhoff, C. and Pensalfini, A. and Rigoglioso, A. and Jiang, Y. and Nixon, R. A.},
  title   = {{Evidence that the rab5 effector APPL1 mediates APP-βCTF-induced dysfunction of endosomes in Down syndrome and Alzheimer's disease}},
  journal = {Molecular psychiatry},
  year    = {2016},
  doi     = {10.1038/mp.2015.97},
  pmid    = {26194181},
  url     = {https://doi.org/10.1038/mp.2015.97}
}

@article{annus2016-26362596,
  author  = {Annus, T. and Wilson, L. R. and Hong, Y. T. and Acosta-Cabronero, J. and Fryer, T. D. and Cardenas-Blanco, A. and Smith, R. and Boros, I. and others},
  title   = {{The pattern of amyloid accumulation in the brains of adults with Down syndrome}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2016},
  doi     = {10.1016/j.jalz.2015.07.490},
  pmid    = {26362596},
  url     = {https://doi.org/10.1016/j.jalz.2015.07.490}
}

@article{stgeorgehyslop1987-2880399,
  author  = {St George-Hyslop, P. H. and Tanzi, R. E. and Polinsky, R. J. and Haines, J. L. and Nee, L. and Watkins, P. C. and Myers, R. H. and Feldman, R. G. and others},
  title   = {{The genetic defect causing familial Alzheimer's disease maps on chromosome 21}},
  journal = {Science (New York, N.Y.)},
  year    = {1987},
  doi     = {10.1126/science.2880399},
  pmid    = {2880399},
  url     = {https://doi.org/10.1126/science.2880399}
}

@article{roizen2003-12699967,
  author  = {Roizen, N. J. and Patterson, D.},
  title   = {{Down's syndrome}},
  journal = {Lancet (London, England)},
  year    = {2003},
  doi     = {10.1016/s0140-6736(03)12987-x},
  pmid    = {12699967},
  url     = {https://doi.org/10.1016/s0140-6736(03)12987-x}
}

@article{busciglio1995-8524410,
  author  = {Busciglio, J. and Yankner, B. A.},
  title   = {{Apoptosis and increased generation of reactive oxygen species in Down's syndrome neurons in vitro}},
  journal = {Nature},
  year    = {1995},
  doi     = {10.1038/378776a0},
  pmid    = {8524410},
  url     = {https://doi.org/10.1038/378776a0}
}

@article{vanleeuwen1998-9422699,
  author  = {van Leeuwen, F. W. and de Kleijn, D. P. and van den Hurk, H. H. and Neubauer, A. and Sonnemans, M. A. and Sluijs, J. A. and Köycü, S. and Ramdjielal, R. D. and others},
  title   = {{Frameshift mutants of beta amyloid precursor protein and ubiquitin-B in Alzheimer's and Down patients}},
  journal = {Science (New York, N.Y.)},
  year    = {1998},
  doi     = {10.1126/science.279.5348.242},
  pmid    = {9422699},
  url     = {https://doi.org/10.1126/science.279.5348.242}
}

@article{delabar1987-2950593,
  author  = {Delabar, J. M. and Goldgaber, D. and Lamour, Y. and Nicole, A. and Huret, J. L. and de Grouchy, J. and Brown, P. and Gajdusek, D. C. and others},
  title   = {{Beta amyloid gene duplication in Alzheimer's disease and karyotypically normal Down syndrome}},
  journal = {Science (New York, N.Y.)},
  year    = {1987},
  doi     = {10.1126/science.2950593},
  pmid    = {2950593},
  url     = {https://doi.org/10.1126/science.2950593}
}

@article{izzo2018-30134785,
  author  = {Izzo, A. and Mollo, N. and Nitti, M. and Paladino, S. and Calì, G. and Genesio, R. and Bonfiglio, F. and Cicatiello, R. and others},
  title   = {{Mitochondrial dysfunction in down syndrome: molecular mechanisms and therapeutic targets}},
  journal = {Molecular medicine (Cambridge, Mass.)},
  year    = {2018},
  doi     = {10.1186/s10020-018-0004-y},
  pmid    = {30134785},
  url     = {https://doi.org/10.1186/s10020-018-0004-y}
}

@article{lott2001-11553933,
  author  = {Lott, I. T. and Head, E.},
  title   = {{Down syndrome and Alzheimer's disease: a link between development and aging}},
  journal = {Mental retardation and developmental disabilities research reviews},
  year    = {2001},
  doi     = {10.1002/mrdd.1025},
  pmid    = {11553933},
  url     = {https://doi.org/10.1002/mrdd.1025}
}

@article{hamlett2017-27755974,
  author  = {Hamlett, E. D. and Goetzl, E. J. and Ledreux, A. and Vasilevko, V. and Boger, H. A. and LaRosa, A. and Clark, D. and Carroll, S. L. and others},
  title   = {{Neuronal exosomes reveal Alzheimer's disease biomarkers in Down syndrome}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2017},
  doi     = {10.1016/j.jalz.2016.08.012},
  pmid    = {27755974},
  url     = {https://doi.org/10.1016/j.jalz.2016.08.012}
}

@article{xu2022-35661546,
  author  = {Xu, Keren and Li, Shaobo and Muskens, Ivo S and Elliott, Natalina and Myint, Swe Swe and Pandey, Priyatama and Hansen, Helen M and Morimoto, Libby M and others},
  title   = {{Accelerated epigenetic aging in newborns with Down syndrome}},
  journal = {Aging cell},
  year    = {2022},
  doi     = {10.1111/acel.13652},
  pmid    = {35661546},
  url     = {https://doi.org/10.1111/acel.13652}
}

@article{johannesson2021-34091073,
  author  = {Johannesson, Malin and Sahlin, Charlotte and Söderberg, Linda and Basun, Hans and Fälting, Johanna and Möller, Christer and Zachrisson, Olof and Sunnemark, Dan and others},
  title   = {{Elevated soluble amyloid beta protofibrils in Down syndrome and Alzheimer's disease}},
  journal = {Molecular and cellular neurosciences},
  year    = {2021},
  doi     = {10.1016/j.mcn.2021.103641},
  pmid    = {34091073},
  url     = {https://doi.org/10.1016/j.mcn.2021.103641}
}

@article{ichimata2022-35311708,
  author  = {Ichimata, Shojiro and Yoshida, Koji and Visanji, Naomi P and Lang, Anthony E and Nishida, Naoki and Kovacs, Gabor G},
  title   = {{Patterns of Mixed Pathologies in Down Syndrome}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2022},
  doi     = {10.3233/jad-215675},
  pmid    = {35311708},
  url     = {https://doi.org/10.3233/jad-215675}
}

@article{lamb1993-8220418,
  author  = {Lamb, B. T. and Sisodia, S. S. and Lawler, A. M. and Slunt, H. H. and Kitt, C. A. and Kearns, W. G. and Pearson, P. L. and Price, D. L. and others},
  title   = {{Introduction and expression of the 400 kilobase amyloid precursor protein gene in transgenic mice [corrected]}},
  journal = {Nature genetics},
  year    = {1993},
  doi     = {10.1038/ng0993-22},
  pmid    = {8220418},
  url     = {https://doi.org/10.1038/ng0993-22}
}

@article{asim2015-26062604,
  author  = {Asim, A. and Kumar, A. and Muthuswamy, S. and Jain, S. and Agarwal, S.},
  title   = {{"Down syndrome: an insight of the disease"}},
  journal = {Journal of biomedical science},
  year    = {2015},
  doi     = {10.1186/s12929-015-0138-y},
  pmid    = {26062604},
  url     = {https://doi.org/10.1186/s12929-015-0138-y}
}

@article{duchon2016-27375444,
  author  = {Duchon, A. and Herault, Y.},
  title   = {{DYRK1A, a Dosage-Sensitive Gene Involved in Neurodevelopmental Disorders, Is a Target for Drug Development in Down Syndrome}},
  journal = {Frontiers in behavioral neuroscience},
  year    = {2016},
  doi     = {10.3389/fnbeh.2016.00104},
  pmid    = {27375444},
  url     = {https://doi.org/10.3389/fnbeh.2016.00104}
}

@article{wiseman2009-19297404,
  author  = {Wiseman, F. K. and Alford, K. A. and Tybulewicz, V. L. and Fisher, E. M.},
  title   = {{Down syndrome--recent progress and future prospects}},
  journal = {Human molecular genetics},
  year    = {2009},
  doi     = {10.1093/hmg/ddp010},
  pmid    = {19297404},
  url     = {https://doi.org/10.1093/hmg/ddp010}
}

@article{karmiloffsmith2016-27019699,
  author  = {Karmiloff-Smith, A. and Al-Janabi, T. and D'Souza, H. and Groet, J. and Massand, E. and Mok, K. and Startin, C. and Fisher, E. and others},
  title   = {{The importance of understanding individual differences in Down syndrome}},
  journal = {F1000Research},
  year    = {2016},
  doi     = {10.12688/f1000research.7506.1},
  pmid    = {27019699},
  url     = {https://doi.org/10.12688/f1000research.7506.1}
}

@article{torres2018-28965914,
  author  = {Torres, Maria D and Garcia, Octavio and Tang, Cindy and Busciglio, Jorge},
  title   = {{Dendritic spine pathology and thrombospondin-1 deficits in Down syndrome}},
  journal = {Free radical biology \& medicine},
  year    = {2018},
  doi     = {10.1016/j.freeradbiomed.2017.09.025},
  pmid    = {28965914},
  url     = {https://doi.org/10.1016/j.freeradbiomed.2017.09.025}
}

@article{zis2018-28870521,
  author  = {Zis, P. and Strydom, A.},
  title   = {{Clinical aspects and biomarkers of Alzheimer's disease in Down syndrome}},
  journal = {Free radical biology \& medicine},
  year    = {2018},
  doi     = {10.1016/j.freeradbiomed.2017.08.024},
  pmid    = {28870521},
  url     = {https://doi.org/10.1016/j.freeradbiomed.2017.08.024}
}

@article{tcw2017-28003277,
  author  = {Tcw, J. and Goate, A. M.},
  title   = {{Genetics of β-Amyloid Precursor Protein in Alzheimer's Disease}},
  journal = {Cold Spring Harbor perspectives in medicine},
  year    = {2017},
  doi     = {10.1101/cshperspect.a024539},
  pmid    = {28003277},
  url     = {https://doi.org/10.1101/cshperspect.a024539}
}

@article{jiang2019-31043483,
  author  = {Jiang, Y. and Sato, Y. and Im, E. and Berg, M. and Bordi, M. and Darji, S. and Kumar, A. and Mohan, P. S. and others},
  title   = {{Lysosomal Dysfunction in Down Syndrome Is APP-Dependent and Mediated by APP-βCTF (C99)}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {2019},
  doi     = {10.1523/jneurosci.0578-19.2019},
  pmid    = {31043483},
  url     = {https://doi.org/10.1523/jneurosci.0578-19.2019}
}

@article{colacurcio2018-28988799,
  author  = {Colacurcio, D. J. and Pensalfini, A. and Jiang, Y. and Nixon, R. A.},
  title   = {{Dysfunction of autophagy and endosomal-lysosomal pathways: Roles in pathogenesis of Down syndrome and Alzheimer's Disease}},
  journal = {Free radical biology \& medicine},
  year    = {2018},
  doi     = {10.1016/j.freeradbiomed.2017.10.001},
  pmid    = {28988799},
  url     = {https://doi.org/10.1016/j.freeradbiomed.2017.10.001}
}

@article{niehrs2006-17143291,
  author  = {Niehrs, C.},
  title   = {{Function and biological roles of the Dickkopf family of Wnt modulators}},
  journal = {Oncogene},
  year    = {2006},
  doi     = {10.1038/sj.onc.1210054},
  pmid    = {17143291},
  url     = {https://doi.org/10.1038/sj.onc.1210054}
}

@article{savulescu2001-12058767,
  author  = {Savulescu, J.},
  title   = {{Procreative beneficence: why we should select the best children}},
  journal = {Bioethics},
  year    = {2001},
  doi     = {10.1111/1467-8519.00251},
  pmid    = {12058767},
  url     = {https://doi.org/10.1111/1467-8519.00251}
}

@article{westlund1999-10051671,
  author  = {Westlund, B. and Parry, D. and Clover, R. and Basson, M. and Johnson, C. D.},
  title   = {{Reverse genetic analysis of Caenorhabditis elegans presenilins reveals redundant but unequal roles for sel-12 and hop-1 in Notch-pathway signaling}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {1999},
  doi     = {10.1073/pnas.96.5.2497},
  pmid    = {10051671},
  url     = {https://doi.org/10.1073/pnas.96.5.2497}
}

@article{smith2001-11578024,
  author  = {Smith, D. S.},
  title   = {{Health care management of adults with Down syndrome}},
  journal = {American family physician},
  year    = {2001},
  pmid    = {11578024}
}

@article{lott2012-22541290,
  author  = {Lott, I. T.},
  title   = {{Neurological phenotypes for Down syndrome across the life span}},
  journal = {Progress in brain research},
  year    = {2012},
  doi     = {10.1016/b978-0-444-54299-1.00006-6},
  pmid    = {22541290},
  url     = {https://doi.org/10.1016/b978-0-444-54299-1.00006-6}
}

@article{fuentes2000-10861295,
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@article{kalman1997-9325475,
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  title   = {{Serum interleukin-6 levels correlate with the severity of dementia in Down syndrome and in Alzheimer's disease}},
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@article{velazquez2013-23643842,
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@article{moon2010-20528079,
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@article{lee2026-1135530e,
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  title   = {{Prevalence of epilepsy and young-onset dementia in adults with intellectual disability: Contrasting Down syndrome and autism diagnoses}},
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  year    = {2026},
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@article{valledor2026-f87dce03,
  author  = {Valledor, M. and Smith, K. and Lawrence, J. B. and Sosa, L. J.},
  title   = {{APP Dosage and Extracellular Domain Variants Drive Distinct Defects in Neurogenesis modeled in Down Syndrome iPS cells}},
  journal = {bioRxiv},
  year    = {2026},
  doi     = {10.64898/2026.08.05.742240},
  url     = {https://doi.org/10.64898/2026.08.05.742240}
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@article{dooling2026-c6cd8c6a,
  author  = {Dooling, B. R. and Vielle, A. and Lucero, E. M. and Rydland, C. and Quang, D. and Summers, R. and Esquer, H. and Coughlan, C. and others},
  title   = {{Trisomy 21 cerebral organoids exhibit Alzheimer’s disease amyloid and apolipoprotein E co-pathologies}},
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  year    = {2026},
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  url     = {https://doi.org/10.64898/2026.07.01.735908}
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@article{west2026-7b94cbdf,
  author  = {West, N. R. and Lindberg, M. F. and Dairou, J. and MacGregor, S. and Puthireddy, S. and Meijer, L. and Bhattacharyya, A.},
  title   = {{Leucettinib-21 decreases dosage effects of DYRK1A in human trisomy 21 iPSC-derived neural cells}},
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  year    = {2026},
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  url     = {https://doi.org/10.64898/2026.02.05.704014}
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@article{patel2025-c5fbe4fa,
  author  = {Patel, D. and Rakowiecki, K. and Lazarov, O.},
  title   = {{Amyloid precursor protein dosage normalization rescues neurogenesis and Alzheimer’s Disease phenotypes associated with Down Syndrome}},
  journal = {bioRxiv},
  year    = {2025},
  doi     = {10.1101/2025.07.30.667706},
  url     = {https://doi.org/10.1101/2025.07.30.667706}
}