% alzhub.org library filter % Source: https://alzhub.org/research?score_min=67&atag=apolipoprotein % 64 entries, in the order the page lists them. Built from alzhub.org's own records. % 0 entries have no readable author in the source record and carry no author field. @article{kunkle2019-30820047, author = {Kunkle, B. W. and Grenier-Boley, B. and Sims, R. and Bis, J. C. and Damotte, V. and Naj, A. C. and Boland, A. and Vronskaya, M. and others}, title = {{Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing}}, journal = {Nature genetics}, year = {2019}, doi = {10.1038/s41588-019-0358-2}, pmid = {30820047}, url = {https://doi.org/10.1038/s41588-019-0358-2} } @article{jansen2015-25988462, author = {Jansen, W. J. and Ossenkoppele, R. and Knol, D. L. and Tijms, B. M. and Scheltens, P. and Verhey, F. R. and Visser, P. J. and {Amyloid Biomarker Study Group} and others}, title = {{Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis}}, journal = {JAMA}, year = {2015}, doi = {10.1001/jama.2015.4668}, pmid = {25988462}, url = {https://doi.org/10.1001/jama.2015.4668} } @article{belloy2023-37930705, author = {Belloy, M. E. and Andrews, S. J. and Le Guen, Y. and Cuccaro, M. and Farrer, L. A. and Napolioni, V. and Greicius, M. D.}, title = {{APOE Genotype and Alzheimer Disease Risk Across Age, Sex, and Population Ancestry}}, journal = {JAMA Neurology}, year = {2023}, doi = {10.1001/jamaneurol.2023.3599}, pmid = {37930705}, url = {https://doi.org/10.1001/jamaneurol.2023.3599} } @article{naj2011-21460841, author = {Naj, A. C. and Jun, G. and Beecham, G. W. and Wang, L. S. and Vardarajan, B. N. and Buros, J. and Gallins, P. J. and Buxbaum, J. D. and others}, title = {{Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease}}, journal = {Nature genetics}, year = {2011}, doi = {10.1038/ng.801}, pmid = {21460841}, url = {https://doi.org/10.1038/ng.801} } @article{wightman2021-34493870, author = {Wightman, D. P. and Jansen, I. E. and Savage, J. E. and Shadrin, A. A. and Bahrami, S. and Holland, D. and Rongve, A. and Børte, S. and others}, title = {{A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease}}, journal = {Nature genetics}, year = {2021}, doi = {10.1038/s41588-021-00921-z}, pmid = {34493870}, url = {https://doi.org/10.1038/s41588-021-00921-z} } @article{bouzid2023-37322115, author = {Bouzid, H. and Belk, J. A. and Jan, M. and Qi, Y. and Sarnowski, C. and Wirth, S. and Ma, L. and Chrostek, M. R. and others}, title = {{Clonal hematopoiesis is associated with protection from Alzheimer's disease}}, journal = {Nature medicine}, year = {2023}, doi = {10.1038/s41591-023-02397-2}, pmid = {37322115}, url = {https://doi.org/10.1038/s41591-023-02397-2} } @article{garatachea2015-975b7ad3, author = {Garatachea, Nuria and Marín, Pedro J. and Santos-Lozano, Alejandro and Sanchis-Gomar, Fabian and Emanuele, Enzo and Lucia, Alejandro}, title = {{The ApoE Gene Is Related with Exceptional Longevity: A Systematic Review and Meta-Analysis}}, journal = {Rejuvenation Research}, year = {2015}, doi = {10.1089/rej.2014.1605}, url = {https://doi.org/10.1089/rej.2014.1605} } @article{solomon2018-29356827, author = {Solomon, A. and Turunen, H. and Ngandu, T. and Peltonen, M. and Levälahti, E. and Helisalmi, S. and Antikainen, R. and Bäckman, L. and others}, title = {{Effect of the Apolipoprotein E Genotype on Cognitive Change During a Multidomain Lifestyle Intervention: A Subgroup Analysis of a Randomized Clinical Trial}}, journal = {JAMA neurology}, year = {2018}, doi = {10.1001/jamaneurol.2017.4365}, pmid = {29356827}, url = {https://doi.org/10.1001/jamaneurol.2017.4365} } @article{seshadri2010-20460622, author = {Seshadri, S. and Fitzpatrick, A. L. and Ikram, M. A. and DeStefano, A. L. and Gudnason, V. and Boada, M. and Bis, J. C. and Smith, A. V. and others}, title = {{Genome-wide analysis of genetic loci associated with Alzheimer disease}}, journal = {JAMA}, year = {2010}, doi = {10.1001/jama.2010.574}, pmid = {20460622}, url = {https://doi.org/10.1001/jama.2010.574} } @article{reitz2013-23571587, author = {Reitz, C. and Jun, G. and Naj, A. and Rajbhandary, R. and Vardarajan, B. N. and Wang, L. S. and Valladares, O. and Lin, C. F. and others}, title = {{Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans}}, journal = {JAMA}, year = {2013}, doi = {10.1001/jama.2013.2973}, pmid = {23571587}, url = {https://doi.org/10.1001/jama.2013.2973} } @article{kunkle2021-33074286, author = {Kunkle, B. W. and Schmidt, M. and Klein, H. U. and Naj, A. C. and Hamilton-Nelson, K. L. and Larson, E. B. and Evans, D. A. and De Jager, P. L. and others}, title = {{Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis}}, journal = {JAMA neurology}, year = {2021}, doi = {10.1001/jamaneurol.2020.3536}, pmid = {33074286}, url = {https://doi.org/10.1001/jamaneurol.2020.3536} } @article{alves2023-36973044, author = {Alves, F. and Kalinowski, P. and Ayton, S.}, title = {{Accelerated Brain Volume Loss Caused by Anti-β-Amyloid Drugs: A Systematic Review and Meta-analysis}}, journal = {Neurology}, year = {2023}, doi = {10.1212/wnl.0000000000207156}, pmid = {36973044}, url = {https://doi.org/10.1212/wnl.0000000000207156} } @article{rajabli2025-40676597, author = {Rajabli, F. and Benchek, P. and Tosto, G. and Kushch, N. and Sha, J. and Bazemore, K. and Zhu, C. and Lee, W. P. and others}, title = {{Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies known and novel cross-population and ancestry-specific associations as novel risk loci for Alzheimer's disease}}, journal = {Genome biology}, year = {2025}, doi = {10.1186/s13059-025-03564-z}, pmid = {40676597}, url = {https://doi.org/10.1186/s13059-025-03564-z} } @article{bergeron2018-30255971, author = {Bergeron, D. and Gorno-Tempini, M. L. and Rabinovici, G. D. and Santos-Santos, M. A. and Seeley, W. and Miller, B. L. and Pijnenburg, Y. and Keulen, M. A. and others}, title = {{Prevalence of amyloid-β pathology in distinct variants of primary progressive aphasia}}, journal = {Annals of neurology}, year = {2018}, doi = {10.1002/ana.25333}, pmid = {30255971}, url = {https://doi.org/10.1002/ana.25333} } @article{xu2025-40067298, author = {Xu, X. and Kwon, J. and Yan, R. and Apio, C. and Song, S. and Heo, G. and Yang, Q. and Timsina, J. and others}, title = {{Sex Differences in Apolipoprotein E and Alzheimer Disease Pathology Across Ancestries}}, journal = {JAMA network open}, year = {2025}, doi = {10.1001/jamanetworkopen.2025.0562}, pmid = {40067298}, url = {https://doi.org/10.1001/jamanetworkopen.2025.0562} } @article{altmann2014-24623176, author = {Altmann, A. and Tian, L. and Henderson, V. W. and Greicius, M. D. and {Alzheimer's Disease Neuroimaging Initiative Investigators}}, title = {{Sex modifies the APOE-related risk of developing Alzheimer disease}}, journal = {Annals of neurology}, year = {2014}, doi = {10.1002/ana.24135}, pmid = {24623176}, url = {https://doi.org/10.1002/ana.24135} } @article{neu2017-28846757, author = {Neu, S. C. and Pa, J. and Kukull, W. and Beekly, D. and Kuzma, A. and Gangadharan, P. and Wang, L. S. and Romero, K. and others}, title = {{Apolipoprotein E Genotype and Sex Risk Factors for Alzheimer Disease: A Meta-analysis}}, journal = {JAMA neurology}, year = {2017}, doi = {10.1001/jamaneurol.2017.2188}, pmid = {28846757}, url = {https://doi.org/10.1001/jamaneurol.2017.2188} } @article{villemagne2013-23477989, author = {Villemagne, V. L. and Burnham, S. and Bourgeat, P. and Brown, B. and Ellis, K. A. and Salvado, O. and Szoeke, C. and Macaulay, S. L. and others}, title = {{Amyloid β deposition, neurodegeneration, and cognitive decline in sporadic Alzheimer's disease: a prospective cohort study}}, journal = {The Lancet. Neurology}, year = {2013}, doi = {10.1016/s1474-4422(13)70044-9}, pmid = {23477989}, url = {https://doi.org/10.1016/s1474-4422(13)70044-9} } @article{liu2015-24838911, author = {Liu, Y. and Yu, J. T. and Wang, H. F. and Han, P. R. and Tan, C. C. and Wang, C. and Meng, X. F. and Risacher, S. L. and others}, title = {{APOE genotype and neuroimaging markers of Alzheimer's disease: systematic review and meta-analysis}}, journal = {Journal of neurology, neurosurgery, and psychiatry}, year = {2015}, doi = {10.1136/jnnp-2014-307719}, pmid = {24838911}, url = {https://doi.org/10.1136/jnnp-2014-307719} } @article{serranopozo2021-33340485, author = {Serrano-Pozo, A. and Das, S. and Hyman, B. T.}, title = {{APOE and Alzheimer's disease: advances in genetics, pathophysiology, and therapeutic approaches}}, journal = {The Lancet. Neurology}, year = {2021}, doi = {10.1016/s1474-4422(20)30412-9}, pmid = {33340485}, url = {https://doi.org/10.1016/s1474-4422(20)30412-9} } @article{green2009-19605829, author = {Green, R. C. and Roberts, J. S. and Cupples, L. A. and Relkin, N. R. and Whitehouse, P. J. and Brown, T. and Eckert, S. L. and Butson, M. and others}, title = {{Disclosure of APOE genotype for risk of Alzheimer's disease}}, journal = {The New England journal of medicine}, year = {2009}, doi = {10.1056/nejmoa0809578}, pmid = {19605829}, url = {https://doi.org/10.1056/nejmoa0809578} } @article{leguen2023-36809323, author = {Le Guen, Y. and Raulin, A. C. and Logue, M. W. and Sherva, R. and Belloy, M. E. and Eger, S. J. and Chen, A. and Kennedy, G. and Kuchenbecker, L. and O'Leary, J. P. and Zhang, R. and Merritt, V. C. and others}, title = {{Association of African Ancestry-Specific APOE Missense Variant R145C With Risk of Alzheimer Disease}}, journal = {JAMA}, year = {2023}, doi = {10.1001/jama.2023.0268}, pmid = {36809323}, url = {https://doi.org/10.1001/jama.2023.0268} } @article{woo2025-41451854, author = {Woo, Marcel S and Macedo, Arthur C and Hosseini, Seyyed Ali and Therriault, Joseph and Wang, Yi-Ting and Rahmouni, Nesrine and Aumont, Étienne and Servaes, Stijn and others}, title = {{APOE ɛ4 carriership determines a faster plasma p-tau217 progression in Aβ-positive individuals}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2025}, doi = {10.1002/alz.71048}, pmid = {41451854}, url = {https://doi.org/10.1002/alz.71048} } @article{quiroz2024-38899694, author = {Quiroz, Y. T. and Aguillon, D. and Aguirre-Acevedo, D. C. and Vasquez, D. and Zuluaga, Y. and Baena, A. Y. and Madrigal, L. and Hincapié, L. and Sanchez, J. S. and Langella, S. and Posada-Duque, R. and Littau, J. L. and others}, title = {{APOE3 Christchurch Heterozygosity and Autosomal Dominant Alzheimer's Disease}}, journal = {New England Journal of Medicine}, year = {2024}, doi = {10.1056/NEJMoa2308583}, pmid = {38899694}, url = {https://doi.org/10.1056/NEJMoa2308583} } @article{bhattarai2024-38598053, author = {Bhattarai, P. and Gunasekaran, T. I. and Belloy, M. E. and Reyes-Dumeyer, D. and Jülich, D. and Tayran, H. and Yilmaz, E. and Flaherty, D. and Turgutalp, B. and Sukumar, G. and Alba, C. and McGrath, E. M. and others}, title = {{Rare genetic variation in fibronectin 1 (FN1) protects against APOEε4 in Alzheimer's disease}}, journal = {Acta Neuropathologica}, year = {2024}, doi = {10.1007/s00401-024-02721-1}, pmid = {38598053}, url = {https://doi.org/10.1007/s00401-024-02721-1} } @article{chapuis2013-23399914, author = {Chapuis, J. and Hansmannel, F. and Gistelinck, M. and Mounier, A. and Van Cauwenberghe, C. and Kolen, K. V. and Geller, F. and Sottejeau, Y. and others}, title = {{Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology}}, journal = {Molecular psychiatry}, year = {2013}, doi = {10.1038/mp.2013.1}, pmid = {23399914}, url = {https://doi.org/10.1038/mp.2013.1} } @article{naj2014-25199842, author = {Naj, A. C. and Jun, G. and Reitz, C. and Kunkle, B. W. and Perry, W. and Park, Y. S. and Beecham, G. W. and Rajbhandary, R. A. and others}, title = {{Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study}}, journal = {JAMA neurology}, year = {2014}, doi = {10.1001/jamaneurol.2014.1491}, pmid = {25199842}, url = {https://doi.org/10.1001/jamaneurol.2014.1491} } @article{nelson2014-24770881, author = {Nelson, P. T. and Estus, S. and Abner, E. L. and Parikh, I. and Malik, M. and Neltner, J. H. and Ighodaro, E. and Wang, W. X. and others}, title = {{ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology}}, journal = {Acta neuropathologica}, year = {2014}, doi = {10.1007/s00401-014-1282-2}, pmid = {24770881}, url = {https://doi.org/10.1007/s00401-014-1282-2} } @article{huang2024-38501315, author = {Huang, S. Y. and Zhang, Y. R. and Guo, Y. and Du, J. and Ren, P. and Wu, B. S. and Feng, J. F. and {Alzheimer's Disease Neuroimaging Initiative} and Cheng, W. and Yu, J. T.}, title = {{Glymphatic system dysfunction predicts amyloid deposition, neurodegeneration, and clinical progression in Alzheimer's disease}}, journal = {Alzheimer's \& Dementia}, year = {2024}, doi = {10.1002/alz.13789}, pmid = {38501315}, url = {https://doi.org/10.1002/alz.13789} } @article{raghavan2020-32568366, author = {Raghavan, N. S. and Dumitrescu, L. and Mormino, E. and Mahoney, E. R. and Lee, A. J. and Gao, Y. and Bilgel, M. and Goldstein, D. and others}, title = {{Association Between Common Variants in RBFOX1, an RNA-Binding Protein, and Brain Amyloidosis in Early and Preclinical Alzheimer Disease}}, journal = {JAMA neurology}, year = {2020}, doi = {10.1001/jamaneurol.2020.1760}, pmid = {32568366}, url = {https://doi.org/10.1001/jamaneurol.2020.1760} } @article{roostaei2017-27021820, author = {Roostaei, T. and Nazeri, A. and Felsky, D. and De Jager, P. L. and Schneider, J. A. and Pollock, B. G. and Bennett, D. A. and Voineskos, A. N. and others}, title = {{Genome-wide interaction study of brain beta-amyloid burden and cognitive impairment in Alzheimer's disease}}, journal = {Molecular psychiatry}, year = {2017}, doi = {10.1038/mp.2016.35}, pmid = {27021820}, url = {https://doi.org/10.1038/mp.2016.35} } @article{broce2018-29315334, author = {Broce, I. and Karch, C. M. and Wen, N. and Fan, C. C. and Wang, Y. and Tan, C. H. and Kouri, N. and Ross, O. A. and others}, title = {{Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies}}, journal = {PLoS medicine}, year = {2018}, doi = {10.1371/journal.pmed.1002487}, pmid = {29315334}, url = {https://doi.org/10.1371/journal.pmed.1002487} } @article{farrer1997-9343467, author = {Farrer, L. A. and Cupples, L. A. and Haines, J. L. and Hyman, B. and Kukull, W. A. and Mayeux, R. and Myers, R. H. and Pericak-Vance, M. A. and others}, title = {{Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium}}, journal = {JAMA}, year = {1997}, doi = {10.1001/jama.1997.03550160069041}, pmid = {9343467}, url = {https://doi.org/10.1001/jama.1997.03550160069041} } @article{tang1998-9508150, author = {Tang, M. X. and Stern, Y. and Marder, K. and Bell, K. and Gurland, B. and Lantigua, R. and Andrews, H. and Feng, L. and others}, title = {{The APOE-epsilon4 allele and the risk of Alzheimer disease among African Americans, whites, and Hispanics}}, journal = {JAMA}, year = {1998}, doi = {10.1001/jama.279.10.751}, pmid = {9508150}, url = {https://doi.org/10.1001/jama.279.10.751} } @article{dube2019-31591557, author = {Dube, U. and Del-Aguila, J. L. and Li, Z. and Budde, J. P. and Jiang, S. and Hsu, S. and Ibanez, L. and Fernandez, M. V. and others}, title = {{An atlas of cortical circular RNA expression in Alzheimer disease brains demonstrates clinical and pathological associations}}, journal = {Nature neuroscience}, year = {2019}, doi = {10.1038/s41593-019-0501-5}, pmid = {31591557}, url = {https://doi.org/10.1038/s41593-019-0501-5} } @article{mirza2019-31575706, author = {Mirza, S. S. and Saeed, U. and Knight, J. and Ramirez, J. and Stuss, D. T. and Keith, J. and Nestor, S. M. and Yu, D. and others}, title = {{APOE ε4, white matter hyperintensities, and cognition in Alzheimer and Lewy body dementia}}, journal = {Neurology}, year = {2019}, doi = {10.1212/wnl.0000000000008377}, pmid = {31575706}, url = {https://doi.org/10.1212/wnl.0000000000008377} } @article{vanderlee2018-29555425, author = {van der Lee, S. J. and Wolters, F. J. and Ikram, M. K. and Hofman, A. and Ikram, M. A. and Amin, N. and van Duijn, C. M.}, title = {{The effect of APOE and other common genetic variants on the onset of Alzheimer's disease and dementia: a community-based cohort study}}, journal = {The Lancet. Neurology}, year = {2018}, doi = {10.1016/s1474-4422(18)30053-x}, pmid = {29555425}, url = {https://doi.org/10.1016/s1474-4422(18)30053-x} } @article{caselli2009-19605830, author = {Caselli, R. J. and Dueck, A. C. and Osborne, D. and Sabbagh, M. N. and Connor, D. J. and Ahern, G. L. and Baxter, L. C. and Rapcsak, S. Z. and others}, title = {{Longitudinal modeling of age-related memory decline and the APOE epsilon4 effect}}, journal = {The New England journal of medicine}, year = {2009}, doi = {10.1056/nejmoa0809437}, pmid = {19605830}, url = {https://doi.org/10.1056/nejmoa0809437} } @article{tsuang2013-23407718, author = {Tsuang, D. and Leverenz, J. B. and Lopez, O. L. and Hamilton, R. L. and Bennett, D. A. and Schneider, J. A. and Buchman, A. S. and Larson, E. B. and others}, title = {{APOE ε4 increases risk for dementia in pure synucleinopathies}}, journal = {JAMA neurology}, year = {2013}, doi = {10.1001/jamaneurol.2013.600}, pmid = {23407718}, url = {https://doi.org/10.1001/jamaneurol.2013.600} } @article{slooter1998-9678314, author = {Slooter, A. J. and Cruts, M. and Kalmijn, S. and Hofman, A. and Breteler, M. M. and Van Broeckhoven, C. and van Duijn, C. M.}, title = {{Risk estimates of dementia by apolipoprotein E genotypes from a population-based incidence study: the Rotterdam Study}}, journal = {Archives of neurology}, year = {1998}, doi = {10.1001/archneur.55.7.964}, pmid = {9678314}, url = {https://doi.org/10.1001/archneur.55.7.964} } @article{miyashita2013-23565137, author = {Miyashita, A. and Koike, A. and Jun, G. and Wang, L. S. and Takahashi, S. and Matsubara, E. and Kawarabayashi, T. and Shoji, M. and others}, title = {{SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians}}, journal = {PloS one}, year = {2013}, doi = {10.1371/journal.pone.0058618}, pmid = {23565137}, url = {https://doi.org/10.1371/journal.pone.0058618} } @article{chauhan2015-25670335, author = {Chauhan, G. and Adams, H. H. H. and Bis, J. C. and Weinstein, G. and Yu, L. and Töglhofer, A. M. and Smith, A. V. and van der Lee, S. J. and others}, title = {{Association of Alzheimer's disease GWAS loci with MRI markers of brain aging}}, journal = {Neurobiology of aging}, year = {2015}, doi = {10.1016/j.neurobiolaging.2014.12.028}, pmid = {25670335}, url = {https://doi.org/10.1016/j.neurobiolaging.2014.12.028} } @article{rafii2018-29582053, author = {Rafii, M. S. and Tuszynski, M. H. and Thomas, R. G. and Barba, D. and Brewer, J. B. and Rissman, R. A. and Siffert, J. and Aisen, P. S. and others}, title = {{Adeno-Associated Viral Vector (Serotype 2)-Nerve Growth Factor for Patients With Alzheimer Disease: A Randomized Clinical Trial}}, journal = {JAMA neurology}, year = {2018}, doi = {10.1001/jamaneurol.2018.0233}, pmid = {29582053}, url = {https://doi.org/10.1001/jamaneurol.2018.0233} } @article{fortea2024-38710950, author = {Fortea, J. and Pegueroles, J. and Alcolea, D. and Belbin, O. and Dols-Icardo, O. and Vaqué-Alcázar, L. and Videla, L. and Gispert, J. D. and others}, title = {{APOE4 homozygozity represents a distinct genetic form of Alzheimer's disease}}, journal = {Nature medicine}, year = {2024}, doi = {10.1038/s41591-024-02931-w}, pmid = {38710950}, url = {https://doi.org/10.1038/s41591-024-02931-w} } @article{yu2015-25365775, author = {Yu, L. and Chibnik, L. B. and Srivastava, G. P. and Pochet, N. and Yang, J. and Xu, J. and Kozubek, J. and Obholzer, N. and others}, title = {{Association of Brain DNA methylation in SORL1, ABCA7, HLA-DRB5, SLC24A4, and BIN1 with pathological diagnosis of Alzheimer disease}}, journal = {JAMA neurology}, year = {2015}, doi = {10.1001/jamaneurol.2014.3049}, pmid = {25365775}, url = {https://doi.org/10.1001/jamaneurol.2014.3049} } @article{ganguli2000-10867779, author = {Ganguli, M. and Chandra, V. and Kamboh, M. I. and Johnston, J. M. and Dodge, H. H. and Thelma, B. K. and Juyal, R. C. and Pandav, R. and others}, title = {{Apolipoprotein E polymorphism and Alzheimer disease: The Indo-US Cross-National Dementia Study}}, journal = {Archives of neurology}, year = {2000}, doi = {10.1001/archneur.57.6.824}, pmid = {10867779}, url = {https://doi.org/10.1001/archneur.57.6.824} } @article{bettens2012-22248099, author = {Bettens, K. and Brouwers, N. and Engelborghs, S. and Lambert, J. C. and Rogaeva, E. and Vandenberghe, R. and Le Bastard, N. and Pasquier, F. and others}, title = {{Both common variations and rare non-synonymous substitutions and small insertion/deletions in CLU are associated with increased Alzheimer risk}}, journal = {Molecular neurodegeneration}, year = {2012}, doi = {10.1186/1750-1326-7-3}, pmid = {22248099}, url = {https://doi.org/10.1186/1750-1326-7-3} } @article{petersen1995-7646655, author = {Petersen, R. C. and Smith, G. E. and Ivnik, R. J. and Tangalos, E. G. and Schaid, D. J. and Thibodeau, S. N. and Kokmen, E. and Waring, S. C. and others}, title = {{Apolipoprotein E status as a predictor of the development of Alzheimer's disease in memory-impaired individuals}}, journal = {JAMA}, year = {1995}, doi = {10.1001/jama.1995.03520400044042}, pmid = {7646655}, url = {https://doi.org/10.1001/jama.1995.03520400044042} } @article{holstege2022-36411364, author = {Holstege, H. and Hulsman, M. and Charbonnier, C. and Grenier-Boley, B. and Quenez, O. and Grozeva, D. and van Rooij, J. G. J. and Sims, R. and others}, title = {{Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer's disease}}, journal = {Nature genetics}, year = {2022}, doi = {10.1038/s41588-022-01208-7}, pmid = {36411364}, url = {https://doi.org/10.1038/s41588-022-01208-7} } @article{chouraki2015-25217292, author = {Chouraki, V. and Beiser, A. and Younkin, L. and Preis, SR. and Weinstein, G. and Hansson, O. and Skoog, I. and Lambert, J. C. and others}, title = {{Plasma amyloid-β and risk of Alzheimer's disease in the Framingham Heart Study}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2015}, doi = {10.1016/j.jalz.2014.07.001}, pmid = {25217292}, url = {https://doi.org/10.1016/j.jalz.2014.07.001} } @article{dumanski2016-27231129, author = {Dumanski, J. P. and Lambert, J. C. and Rasi, C. and Giedraitis, V. and Davies, H. and Grenier-Boley, B. and Lindgren, C. M. and Campion, D. and others}, title = {{Mosaic Loss of Chromosome Y in Blood Is Associated with Alzheimer Disease}}, journal = {American journal of human genetics}, year = {2016}, doi = {10.1016/j.ajhg.2016.05.014}, pmid = {27231129}, url = {https://doi.org/10.1016/j.ajhg.2016.05.014} } @article{choi2026-42937433, author = {Choi, Alex and Haystead, Alice and D'Cunha, Rachel and Hsu, John and Zhu, Michael and Johnson, Kim G and Whitson, Heather and Grewal, Dilraj S and others}, title = {{Longitudinal Multimodal Retinal Imaging in Cognitively Normal Apolipoprotein E4 Carriers and Noncarriers}}, journal = {Translational vision science \& technology}, year = {2026}, doi = {10.1167/tvst.15.10.45}, pmid = {42937433}, url = {https://doi.org/10.1167/tvst.15.10.45} } @article{antolini2021-34531298, author = {Antolini, L. and DiFrancesco, J. C. and Zedde, M. and Basso, G. and Arighi, A. and Shima, A. and Cagnin, A. and Caulo, M. and others}, title = {{Spontaneous ARIA-like Events in Cerebral Amyloid Angiopathy-Related Inflammation: A Multicenter Prospective Longitudinal Cohort Study}}, journal = {Neurology}, year = {2021}, doi = {10.1212/wnl.0000000000012778}, pmid = {34531298}, url = {https://doi.org/10.1212/wnl.0000000000012778} } @article{hanson2013-23779114, author = {Hanson, A. J. and Bayer-Carter, J. L. and Green, P. S. and Montine, T. J. and Wilkinson, C. W. and Baker, L. D. and Watson, G. S. and Bonner, L. M. and others}, title = {{Effect of apolipoprotein E genotype and diet on apolipoprotein E lipidation and amyloid peptides: randomized clinical trial}}, journal = {JAMA neurology}, year = {2013}, doi = {10.1001/jamaneurol.2013.396}, pmid = {23779114}, url = {https://doi.org/10.1001/jamaneurol.2013.396} } @article{leguen2022-35639372, author = {Le Guen, Y. and Belloy, M. E. and Grenier-Boley, B. and de Rojas, I. and Castillo-Morales, A. and Jansen, I. and Nicolas, A. and Bellenguez, C. and others}, title = {{Association of Rare APOE Missense Variants V236E and R251G With Risk of Alzheimer Disease}}, journal = {JAMA neurology}, year = {2022}, doi = {10.1001/jamaneurol.2022.1166}, pmid = {35639372}, url = {https://doi.org/10.1001/jamaneurol.2022.1166} } @article{delgadoperaza2023-37730689, author = {Delgado-Peraza, F. and Nogueras-Ortiz, C. and Simonsen, A. H. and Knight, D. D. and Yao, P. J. and Goetzl, E. J. and Jensen, C. S. and Høgh, P. and others}, title = {{Neuron-derived extracellular vesicles in blood reveal effects of exercise in Alzheimer's disease}}, journal = {Alzheimer's research \& therapy}, year = {2023}, doi = {10.1186/s13195-023-01303-9}, pmid = {37730689}, url = {https://doi.org/10.1186/s13195-023-01303-9} } @article{kapogiannis2015-25342129, author = {Kapogiannis, D. and Boxer, A. and Schwartz, J. B. and Abner, E. L. and Biragyn, A. and Masharani, U. and Frassetto, L. and Petersen, R. C. and others}, title = {{Dysfunctionally phosphorylated type 1 insulin receptor substrate in neural-derived blood exosomes of preclinical Alzheimer's disease}}, journal = {FASEB journal : official publication of the Federation of American Societies for Experimental Biology}, year = {2015}, doi = {10.1096/fj.14-262048}, pmid = {25342129}, url = {https://doi.org/10.1096/fj.14-262048} } @article{shirzadi2023-37843849, author = {Shirzadi, Z. and Schultz, S. A. and Yau, W. W. and Joseph-Mathurin, N. and Fitzpatrick, C. D. and Levin, R. and Kantarci, K. and Preboske, G. M. and others}, title = {{Etiology of White Matter Hyperintensities in Autosomal Dominant and Sporadic Alzheimer Disease}}, journal = {JAMA neurology}, year = {2023}, doi = {10.1001/jamaneurol.2023.3618}, pmid = {37843849}, url = {https://doi.org/10.1001/jamaneurol.2023.3618} } @article{morenograu2019-31473137, author = {Moreno-Grau, S. and de Rojas, I. and Hernández, I. and Quintela, I. and Montrreal, L. and Alegret, M. and Hernández-Olasagarre, B. and Madrid, L. and others}, title = {{Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2019}, doi = {10.1016/j.jalz.2019.06.4950}, pmid = {31473137}, url = {https://doi.org/10.1016/j.jalz.2019.06.4950} } @article{rabin2022-35759327, author = {Rabin, J. S. and Nichols, E. and La Joie, R. and Casaletto, K. B. and Palta, P. and Dams-O'Connor, K. and Kumar, R. G. and George, K. M. and others}, title = {{Cerebral amyloid angiopathy interacts with neuritic amyloid plaques to promote tau and cognitive decline}}, journal = {Brain : a journal of neurology}, year = {2022}, doi = {10.1093/brain/awac178}, pmid = {35759327}, url = {https://doi.org/10.1093/brain/awac178} } @article{eliassonnenschein2011-21493755, author = {Elias-Sonnenschein, L. S. and Viechtbauer, W. and Ramakers, I. H. and Verhey, F. R. and Visser, P. J.}, title = {{Predictive value of APOE-ε4 allele for progression from MCI to AD-type dementia: a meta-analysis}}, journal = {Journal of neurology, neurosurgery, and psychiatry}, year = {2011}, doi = {10.1136/jnnp.2010.231555}, pmid = {21493755}, url = {https://doi.org/10.1136/jnnp.2010.231555} } @article{meyerluehmann2008-18256671, author = {Meyer-Luehmann, M. and Spires-Jones, T. L. and Prada, C. and Garcia-Alloza, M. and de Calignon, A. and Rozkalne, A. and Koenigsknecht-Talboo, J. and Holtzman, D. M. and others}, title = {{Rapid appearance and local toxicity of amyloid-beta plaques in a mouse model of Alzheimer's disease}}, journal = {Nature}, year = {2008}, doi = {10.1038/nature06616}, pmid = {18256671}, url = {https://doi.org/10.1038/nature06616} } @article{jansen2019-30617256, author = {Jansen, Iris E. and Savage, Jeanne E. and Watanabe, Kyoko and Bryois, Julien and Williams, Dylan M. and Steinberg, Stacy and Sealock, Julia and Karlsson, Ida and others}, title = {{Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer’s disease risk}}, journal = {Nature Genetics}, year = {2019}, doi = {10.1038/s41588-018-0311-9}, pmid = {30617256}, url = {https://doi.org/10.1038/s41588-018-0311-9} } @article{ward2012-22179327, author = {Ward, A. and Crean, S. and Mercaldi, C. J. and Collins, J. M. and Boyd, D. and Cook, M. N. and Arrighi, H. M.}, title = {{Prevalence of apolipoprotein E4 genotype and homozygotes (APOE e4/4) among patients diagnosed with Alzheimer's disease: a systematic review and meta-analysis}}, journal = {Neuroepidemiology}, year = {2012}, doi = {10.1159/000334607}, pmid = {22179327}, url = {https://doi.org/10.1159/000334607} }