% alzhub.org library filter
% Source: https://alzhub.org/research?atag=apoe4
% 268 entries, in the order the page lists them. Built from alzhub.org's own records.
% 0 entries have no readable author in the source record and carry no author field.

@article{garatachea2015-975b7ad3,
  author  = {Garatachea, Nuria and Marín, Pedro J. and Santos-Lozano, Alejandro and Sanchis-Gomar, Fabian and Emanuele, Enzo and Lucia, Alejandro},
  title   = {{The ApoE Gene Is Related with Exceptional Longevity: A Systematic Review and Meta-Analysis}},
  journal = {Rejuvenation Research},
  year    = {2015},
  doi     = {10.1089/rej.2014.1605},
  url     = {https://doi.org/10.1089/rej.2014.1605}
}

@article{serranopozo2021-33340485,
  author  = {Serrano-Pozo, A. and Das, S. and Hyman, B. T.},
  title   = {{APOE and Alzheimer's disease: advances in genetics, pathophysiology, and therapeutic approaches}},
  journal = {The Lancet. Neurology},
  year    = {2021},
  doi     = {10.1016/s1474-4422(20)30412-9},
  pmid    = {33340485},
  url     = {https://doi.org/10.1016/s1474-4422(20)30412-9}
}

@article{green2009-19605829,
  author  = {Green, R. C. and Roberts, J. S. and Cupples, L. A. and Relkin, N. R. and Whitehouse, P. J. and Brown, T. and Eckert, S. L. and Butson, M. and others},
  title   = {{Disclosure of APOE genotype for risk of Alzheimer's disease}},
  journal = {The New England journal of medicine},
  year    = {2009},
  doi     = {10.1056/nejmoa0809578},
  pmid    = {19605829},
  url     = {https://doi.org/10.1056/nejmoa0809578}
}

@article{woo2025-41451854,
  author  = {Woo, Marcel S and Macedo, Arthur C and Hosseini, Seyyed Ali and Therriault, Joseph and Wang, Yi-Ting and Rahmouni, Nesrine and Aumont, Étienne and Servaes, Stijn and others},
  title   = {{APOE ɛ4 carriership determines a faster plasma p-tau217 progression in Aβ-positive individuals}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2025},
  doi     = {10.1002/alz.71048},
  pmid    = {41451854},
  url     = {https://doi.org/10.1002/alz.71048}
}

@article{cicognola2025-39817469,
  author  = {Cicognola, C. and Salvadó, G. and Smith, R. and Palmqvist, S. and Stomrud, E. and Betthauser, T. J. and Johnson, S. C. and Janelidze, S. and others},
  title   = {{APOE4 impact on soluble and insoluble tau pathology is mostly influenced by amyloid-β}},
  journal = {Brain : a journal of neurology},
  year    = {2025},
  doi     = {10.1093/brain/awaf016},
  pmid    = {39817469},
  url     = {https://doi.org/10.1093/brain/awaf016}
}

@article{choi2026-42937433,
  author  = {Choi, Alex and Haystead, Alice and D'Cunha, Rachel and Hsu, John and Zhu, Michael and Johnson, Kim G and Whitson, Heather and Grewal, Dilraj S and others},
  title   = {{Longitudinal Multimodal Retinal Imaging in Cognitively Normal Apolipoprotein E4 Carriers and Noncarriers}},
  journal = {Translational vision science \& technology},
  year    = {2026},
  doi     = {10.1167/tvst.15.10.45},
  pmid    = {42937433},
  url     = {https://doi.org/10.1167/tvst.15.10.45}
}

@article{bertram2008-18802446,
  author  = {Bertram, L. and Tanzi, R. E.},
  title   = {{Thirty years of Alzheimer's disease genetics: the implications of systematic meta-analyses}},
  journal = {Nature reviews. Neuroscience},
  year    = {2008},
  doi     = {10.1038/nrn2494},
  pmid    = {18802446},
  url     = {https://doi.org/10.1038/nrn2494}
}

@article{jackson2022-34957486,
  author  = {Jackson, Rosemary J and Meltzer, Jonah C and Nguyen, Huong and Commins, Caitlin and Bennett, Rachel E and Hudry, Eloise and Hyman, Bradley T},
  title   = {{APOE4 derived from astrocytes leads to blood-brain barrier impairment}},
  journal = {Brain : a journal of neurology},
  year    = {2022},
  doi     = {10.1093/brain/awab478},
  pmid    = {34957486},
  url     = {https://doi.org/10.1093/brain/awab478}
}

@article{brookhouser2021-33837271,
  author  = {Brookhouser, Nicholas and Raman, Sreedevi and Frisch, Carlye and Srinivasan, Gayathri and Brafman, David A},
  title   = {{APOE2 mitigates disease-related phenotypes in an isogenic hiPSC-based model of Alzheimer's disease}},
  journal = {Molecular psychiatry},
  year    = {2021},
  doi     = {10.1038/s41380-021-01076-3},
  pmid    = {33837271},
  url     = {https://doi.org/10.1038/s41380-021-01076-3}
}

@article{liu2026-42799898,
  author  = {Liu, Shengyi and Fan, Lingjie and He, Zihua and Yi, Tong and Wang, Jiaqi and Zhao, Junhan and Sander, Josemir W and Zhou, Dong and others},
  title   = {{Association of apolipoprotein E gene with risk, cognition, and prognosis of epilepsy}},
  journal = {Human genetics},
  year    = {2026},
  doi     = {10.1007/s00439-026-02876-9},
  pmid    = {42799898},
  url     = {https://doi.org/10.1007/s00439-026-02876-9}
}

@article{coraglia2026-42169086,
  author  = {Coraglia, Federico and Cecchetti, Giordano and Rugarli, Giulia and Spinelli, Edoardo G and Ghirelli, Alma and Pisano, Stefano and Canu, Elisa and Filippi, Massimo and others},
  title   = {{Plasma ApoE proteotyping for ApoE ε4 stratification in the anti-amyloid therapies era}},
  journal = {Alzheimer's research \& therapy},
  year    = {2026},
  doi     = {10.1186/s13195-026-02089-2},
  pmid    = {42169086},
  url     = {https://doi.org/10.1186/s13195-026-02089-2}
}

@article{faura2020-31958084,
  author  = {Faura, J. and Bustamante, A. and Penalba, A. and Giralt, D. and Simats, A. and Martínez-Sáez, E. and Alcolea, D. and Fortea, J. and others},
  title   = {{CCL23: A Chemokine Associated with Progression from Mild Cognitive Impairment to Alzheimer's Disease}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2020},
  doi     = {10.3233/jad-190753},
  pmid    = {31958084},
  url     = {https://doi.org/10.3233/jad-190753}
}

@article{sapkota2023-37021572,
  author  = {Sapkota, Shraddha and Erickson, Kelsey and Fletcher, Evan and Farias, Sarah E Tomaszewski and Jin, Lee-Way and DeCarli, Charles and {Alzheimer’s Disease Neuroimaging Initiative}},
  title   = {{Vascular Risk Predicts Plasma Amyloid β 42/40 Through Cerebral Amyloid Burden in Apolipoprotein E ε4 Carriers}},
  journal = {Stroke},
  year    = {2023},
  doi     = {10.1161/strokeaha.122.041854},
  pmid    = {37021572},
  url     = {https://doi.org/10.1161/strokeaha.122.041854}
}

@article{chiesa2019-31113760,
  author  = {Chiesa, Patrizia A and Cavedo, Enrica and Vergallo, Andrea and Lista, Simone and Potier, Marie-Claude and Habert, Marie-Odile and Dubois, Bruno and de Schotten, Michel Thiebaut and others},
  title   = {{Differential default mode network trajectories in asymptomatic individuals at risk for Alzheimer's disease}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2019},
  doi     = {10.1016/j.jalz.2019.03.006},
  pmid    = {31113760},
  url     = {https://doi.org/10.1016/j.jalz.2019.03.006}
}

@article{zhang2015-c9959eeb,
  author  = {Zhang, Yong and Zhang, Linlin and Cao, Bo},
  title   = {{The Association Between Serum ApoE Genetic Polymorphism and Serum Lipid Level in Hemodialysis Patients}},
  journal = {Genetic Testing and Molecular Biomarkers},
  year    = {2015},
  doi     = {10.1089/gtmb.2014.0267},
  url     = {https://doi.org/10.1089/gtmb.2014.0267}
}

@article{moysich2000-10642431,
  author  = {Moysich, K B and Freudenheim, J L and Baker, J A and Ambrosone, C B and Bowman, E D and Schisterman, E F and Vena, J E and Shields, P G},
  title   = {{Apolipoprotein E genetic polymorphism, serum lipoproteins, and breast cancer risk}},
  journal = {Molecular carcinogenesis},
  year    = {2000},
  doi     = {10.1002/(sici)1098-2744(200001)27:1<2::aid-mc2>3.0.co;2-w},
  pmid    = {10642431},
  url     = {https://doi.org/10.1002/(sici)1098-2744(200001)27:1<2::aid-mc2>3.0.co;2-w}
}

@article{rodriguez2025-40671162,
  author  = {Rodríguez, A. and Calero, O. and Veiga, S. and Menacho-Román, M. and Arribas, I. and Cano, L. and García-Ribas, G. and Calero, M.},
  title   = {{A novel biochemical analysis for ApoE4 quantification in plasma and discrimination of homozygous and heterozygous APOE ε4 carriers}},
  journal = {Alzheimer's research \& therapy},
  year    = {2025},
  doi     = {10.1186/s13195-025-01811-w},
  pmid    = {40671162},
  url     = {https://doi.org/10.1186/s13195-025-01811-w}
}

@article{henderson2009-19664276,
  author  = {Henderson, S. T. and Vogel, J. L. and Barr, L. J. and Garvin, F. and Jones, J. J. and Costantini, L. C.},
  title   = {{Study of the ketogenic agent AC-1202 in mild to moderate Alzheimer's disease: a randomized, double-blind, placebo-controlled, multicenter trial}},
  journal = {Nutrition \& metabolism},
  year    = {2009},
  doi     = {10.1186/1743-7075-6-31},
  pmid    = {19664276},
  url     = {https://doi.org/10.1186/1743-7075-6-31}
}

@article{ramanan2014-23419831,
  author  = {Ramanan, V. K. and Risacher, S. L. and Nho, K. and Kim, S. and Swaminathan, S. and Shen, L. and Foroud, T. M. and Hakonarson, H. and others},
  title   = {{APOE and BCHE as modulators of cerebral amyloid deposition: a florbetapir PET genome-wide association study}},
  journal = {Molecular psychiatry},
  year    = {2014},
  doi     = {10.1038/mp.2013.19},
  pmid    = {23419831},
  url     = {https://doi.org/10.1038/mp.2013.19}
}

@article{salami2022-2b804420,
  author  = {Salami, Alireza and Adolfsson, Rolf and Andersson, Micael and Blennow, Kaj and Lundquist, Anders and Adolfsson, Annelie Nordin and Schöll, Michael and Zetterberg, Henrik and others},
  title   = {{Association of APOE ɛ4 and Plasma p-tau181 with Preclinical Alzheimer’s Disease and Longitudinal Change in Hippocampus Function}},
  journal = {Journal of Alzheimer's Disease},
  year    = {2022},
  doi     = {10.3233/jad-210673},
  url     = {https://doi.org/10.3233/jad-210673}
}

@article{fu2012-23023945,
  author  = {Fu, Rao and Yanjanin, Nicole M and Elrick, Matthew J and Ware, Christopher and Lieberman, Andrew P and Porter, Forbes D},
  title   = {{Apolipoprotein E genotype and neurological disease onset in Niemann-Pick disease, type C1}},
  journal = {American journal of medical genetics. Part A},
  year    = {2012},
  doi     = {10.1002/ajmg.a.35395},
  pmid    = {23023945},
  url     = {https://doi.org/10.1002/ajmg.a.35395}
}

@article{salvado2022-34877786,
  author  = {Salvadó, Gemma and Ferreira, Daniel and Operto, Grégory and Cumplido-Mayoral, Irene and Arenaza-Urquijo, Eider M and Cacciaglia, Raffaele and Falcon, Carles and Vilor-Tejedor, Natàlia and others},
  title   = {{The protective gene dose effect of the APOE ε2 allele on gray matter volume in cognitively unimpaired individuals}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2022},
  doi     = {10.1002/alz.12487},
  pmid    = {34877786},
  url     = {https://doi.org/10.1002/alz.12487}
}

@article{small2000-10811879,
  author  = {Small, G. W. and Ercoli, L. M. and Silverman, D. H. and Huang, S. C. and Komo, S. and Bookheimer, S. Y. and Lavretsky, H. and Miller, K. and others},
  title   = {{Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer's disease}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {2000},
  doi     = {10.1073/pnas.090106797},
  pmid    = {10811879},
  url     = {https://doi.org/10.1073/pnas.090106797}
}

@article{arboledavelasquez2019-31686034,
  author  = {Arboleda-Velasquez, J. F. and Lopera, F. and O'Hare, M. and Delgado-Tirado, S. and Marino, C. and Chmielewska, N. and Saez-Torres, K. L. and Amarnani, D. and others},
  title   = {{Resistance to autosomal dominant Alzheimer's disease in an APOE3 Christchurch homozygote: a case report}},
  journal = {Nature medicine},
  year    = {2019},
  doi     = {10.1038/s41591-019-0611-3},
  pmid    = {31686034},
  url     = {https://doi.org/10.1038/s41591-019-0611-3}
}

@article{itzhaki1997-9014911,
  author  = {Itzhaki, R. F. and Lin, W. R. and Shang, D. and Wilcock, G. K. and Faragher, B. and Jamieson, G. A.},
  title   = {{Herpes simplex virus type 1 in brain and risk of Alzheimer's disease}},
  journal = {Lancet (London, England)},
  year    = {1997},
  doi     = {10.1016/s0140-6736(96)10149-5},
  pmid    = {9014911},
  url     = {https://doi.org/10.1016/s0140-6736(96)10149-5}
}

@article{agnello2024-39025198,
  author  = {Agnello, Luisa and Gambino, Caterina Maria and Ciaccio, Anna Maria and Piccoli, Tommaso and Blandino, Valeria and Scazzone, Concetta and Sasso, Bruna Lo and Del Ben, Fabio and others},
  title   = {{Exploring the effect of APOE ε4 on biomarkers of neurodegeneration in Alzheimer's disease}},
  journal = {Clinica chimica acta; international journal of clinical chemistry},
  year    = {2024},
  doi     = {10.1016/j.cca.2024.119876},
  pmid    = {39025198},
  url     = {https://doi.org/10.1016/j.cca.2024.119876}
}

@article{liampas2025-40943487,
  author  = {Liampas, Ioannis and Demiri, Silvia and Siokas, Vasileios and Tsika, Antonia and Marogianni, Chrysa and Stamati, Polyxeni and Nasios, Grigorios and Messinis, Lambros and others},
  title   = {{Apolipoprotein E Alleles and Motor Signs in Older Adults with Alzheimer's Dementia}},
  journal = {International journal of molecular sciences},
  year    = {2025},
  doi     = {10.3390/ijms26178562},
  pmid    = {40943487},
  url     = {https://doi.org/10.3390/ijms26178562}
}

@article{gunadi2026-88426919,
  author  = {Gunadi, S. G. A. and Fitrah, Y. A. and Soraya, G. V. and Jannah, A. R. and Sompa, A. W. and Basri, M. I. and Limoa, L. T. and Hara, N. and others},
  title   = {{Clinical Phenotype of Apoe Ɛ4 Carriers In Patients With Vascular Dementia: A Cross-Sectional Study From Indonesia}},
  journal = {F1000Res},
  year    = {2026},
  doi     = {10.12688/f1000research.188901.1},
  url     = {https://doi.org/10.12688/f1000research.188901.1}
}

@article{hartman2001-11476599,
  author  = {Hartman, R. E. and Wozniak, D. F. and Nardi, A. and Olney, J. W. and Sartorius, L. and Holtzman, D. M.},
  title   = {{Behavioral phenotyping of GFAP-apoE3 and -apoE4 transgenic mice: apoE4 mice show profound working memory impairments in the absence of Alzheimer's-like neuropathology}},
  journal = {Experimental neurology},
  year    = {2001},
  doi     = {10.1006/exnr.2001.7715},
  pmid    = {11476599},
  url     = {https://doi.org/10.1006/exnr.2001.7715}
}

@article{haney2024-38480892,
  author  = {Haney, M. S. and Pálovics, R. and Munson, C. N. and Long, C. and Johansson, P. K. and Yip, O. and Dong, W. and Rawat, E. and others},
  title   = {{APOE4/4 is linked to damaging lipid droplets in Alzheimer's disease microglia}},
  journal = {Nature},
  year    = {2024},
  doi     = {10.1038/s41586-024-07185-7},
  pmid    = {38480892},
  url     = {https://doi.org/10.1038/s41586-024-07185-7}
}

@article{ji2024-39702440,
  author  = {Ji, S. and Rosenbloom, M.},
  title   = {{Intracerebral hemorrhage following mild ARIA-H in an APOE ε2 carrier receiving lecanemab}},
  journal = {Alzheimer's research \& therapy},
  year    = {2024},
  doi     = {10.1186/s13195-024-01640-3},
  pmid    = {39702440},
  url     = {https://doi.org/10.1186/s13195-024-01640-3}
}

@article{trigo2024-38312530,
  author  = {Trigo, Arturo Nicolás and Muzzio, Marina and Figueroa, Marcelo Isidro and Alfaro-Gómez, Emma Laura and Bailliet, Graciela and Dopazo, Hernán Javier and Dipierri, José Edgardo},
  title   = {{Apolipoprotein E Polymorphisms in Andean Population of Jujuy, Argentina}},
  journal = {Journal of Alzheimer's disease reports},
  year    = {2024},
  doi     = {10.3233/adr-230061},
  pmid    = {38312530},
  url     = {https://doi.org/10.3233/adr-230061}
}

@article{greenberg1995-7654074,
  author  = {Greenberg, Steven Mark and Rebeck, George William and Vonsattel, Jean Paul and Gómez‐Isla, Teresa and Hyman, Bradley T.},
  title   = {{Apolipoprotein E ϵ4 and cerebral hemorrhage associated with amyloid angiopathy}},
  journal = {Annals of Neurology},
  year    = {1995},
  doi     = {10.1002/ana.410380219},
  pmid    = {7654074},
  url     = {https://doi.org/10.1002/ana.410380219}
}

@article{cahuapablo2015-aa9d6443,
  author  = {Cahua-Pablo, Gabriel and Cruz, Miguel and del Moral-Hernández, Oscar and Leyva-Vázquez, Marco A. and Antúnez-Ortiz, Diana L. and Cahua-Pablo, José A. and Alarcón-Romero, Luz del Carmen and Ortuño-Pineda, Carlos and others},
  title   = {{Elevated Levels of LDL-C are Associated With ApoE4 but Not With the rs688 Polymorphism in the LDLR Gene}},
  journal = {Clinical and Applied Thrombosis/Hemostasis},
  year    = {2015},
  doi     = {10.1177/1076029614568714},
  url     = {https://doi.org/10.1177/1076029614568714}
}

@article{poirier1993-8103819,
  author  = {Poirier, J. and Davignon, J. and Bouthillier, D. and Kogan, S. and Bertrand, P. and Gauthier, S.},
  title   = {{Apolipoprotein E polymorphism and Alzheimer's disease}},
  journal = {Lancet (London, England)},
  year    = {1993},
  doi     = {10.1016/0140-6736(93)91705-q},
  pmid    = {8103819},
  url     = {https://doi.org/10.1016/0140-6736(93)91705-q}
}

@article{zhang2022-35915083,
  author  = {Zhang, Hongsheng and Shao, Lin and Lin, Zhihao and Long, Quan-Xin and Yuan, Huilong and Cai, Lujian and Jiang, Guangtong and Guo, Xiaoyi and others},
  title   = {{APOE interacts with ACE2 inhibiting SARS-CoV-2 cellular entry and inflammation in COVID-19 patients}},
  journal = {Signal transduction and targeted therapy},
  year    = {2022},
  doi     = {10.1038/s41392-022-01118-4},
  pmid    = {35915083},
  url     = {https://doi.org/10.1038/s41392-022-01118-4}
}

@article{kadir2026-42744302,
  author  = {Kadir, Rais Reskiawan A and Bons, Joanna and Hormazabal, Genesis Vega and Kumaar, Prasanna Vadhana Ashok and Gerónimo-Olvera, Cristian and Tshilenge, Kizito-Tshitoko and Pihán, Philippe and Aguirre, Carlos Galicia and others},
  title   = {{The longevity gene APOE2 enhances pericyte function and reduces lipid droplets}},
  journal = {Brain : a journal of neurology},
  year    = {2026},
  doi     = {10.1093/brain/awag311},
  pmid    = {42744302},
  url     = {https://doi.org/10.1093/brain/awag311}
}

@article{cunilopez2026-42749735,
  author  = {Cuní-López, Carla and Root, Jessica T and Hao, Ying and Blomberg, Niek and Hertog, Sascha J Koppes-den and Sacks, Dylan and Trujillo, Amber E and Ghirlando, Rodolfo and others},
  title   = {{APOE genotypes differentially remodel the astrocytic lipid droplet proteome to shape lipid droplet dynamics}},
  journal = {Nature communications},
  year    = {2026},
  doi     = {10.1038/s41467-026-76565-6},
  pmid    = {42749735},
  url     = {https://doi.org/10.1038/s41467-026-76565-6}
}

@article{blacker1997-9008509,
  author  = {Blacker, Deborah and Haines, Jonathan L. and Rodes, L. and Terwedow, Henry A and Go, Rodney C.P. and Harrell, L. E. and Perry, Rodney T. and Bassett, Susan Spear and others},
  title   = {{ApoE-4 and Age at Onset of Alzheimer's Disease}},
  journal = {Neurology},
  year    = {1997},
  doi     = {10.1212/wnl.48.1.139},
  pmid    = {9008509},
  url     = {https://doi.org/10.1212/wnl.48.1.139}
}

@article{chartierharlin1994-8069300,
  author  = {Chartier‐Harlin, Marie‐Christine and Parfitt, Matthew and Legrain, Sylvie and Pérez‐Tur, Jordi and Brousseau, Thierry and Evans, Alun and Berr, Claudine and Vldal, Odile and others},
  title   = {{Apolipoprotein E, ɛ4 allele as a major risk factor for sporadic early and late-onset forms of Alzheimer's disease: analysis of the 19q13.2 chromosomal region}},
  journal = {Human Molecular Genetics},
  year    = {1994},
  doi     = {10.1093/hmg/3.4.569},
  pmid    = {8069300},
  url     = {https://doi.org/10.1093/hmg/3.4.569}
}

@article{uyrum2015-153a84d1,
  author  = {Uyrum, Ebru and Balbay, Oner and Annakkaya, Ali Nihat and Balbay, Ege Gulec and Silan, Fatma and Arbak, Peri},
  title   = {{The Relationship between Obstructive Sleep Apnea Syndrome and Apolipoprotein E Genetic Variants}},
  journal = {Respiration},
  year    = {2015},
  doi     = {10.1159/000369560},
  url     = {https://doi.org/10.1159/000369560}
}

@article{montagne2020-32376954,
  author  = {Montagne, A. and Nation, D. A. and Sagare, A. P. and Barisano, G. and Sweeney, M. D. and Chakhoyan, A. and Pachicano, M. and Joe, E. and others},
  title   = {{APOE4 leads to blood-brain barrier dysfunction predicting cognitive decline}},
  journal = {Nature},
  year    = {2020},
  doi     = {10.1038/s41586-020-2247-3},
  pmid    = {32376954},
  url     = {https://doi.org/10.1038/s41586-020-2247-3}
}

@article{farrell2025-39d43f22,
  author  = {Farrell, C. and Buhidma, Y. and Mumford, P. and Heywood, W. E. and Hällqvist, J. and Flores-Aguilar, L. and Andrews, E. and Rahimzadah, N. and others},
  title   = {{Apolipoprotein E abundance is elevated in the brains of individuals with Down syndrome-Alzheimer’s disease}},
  journal = {Acta neuropathologica},
  year    = {2025},
  doi     = {10.1101/2025.02.24.639862},
  url     = {https://doi.org/10.1101/2025.02.24.639862}
}

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  title   = {{APOE from astrocytes restores Alzheimer's Aβ-pathology and DAM-like responses in APOE deficient microglia}},
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  title   = {{Comparison of the ApoE allelic variants in the formation of intracerebral Aβ deposits}},
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  title   = {{APOE genotype-dependent differences in human astrocytic energy metabolism}},
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@article{arriaza2025-41134549,
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  title   = {{ApoE is Secreted as a Lipid Nanoparticle by Mammalian Cells: Implications for Alzheimer's Disease Pathogenesis}},
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  year    = {2025},
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  title   = {{Brain-targeting liposome-based APOE2 gene delivery exacerbates soluble amyloid-β accumulation in App NL-G-F mice}},
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@article{mah2023-37014788,
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  title   = {{Apolipoprotein E Recognizes Alzheimer's Disease Associated 3-O Sulfation of Heparan Sulfate}},
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  title   = {{Apolipoprotein E2 Stimulates Protein Synthesis and Promotes Melanoma Progression and Metastasis}},
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  year    = {2023},
  doi     = {10.1158/0008-5472.can-23-1252},
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  title   = {{Apolipoprotein E isoform-dependent effects on the processing of Alzheimer's amyloid-β}},
  journal = {Biochimica et biophysica acta. Molecular and cell biology of lipids},
  year    = {2021},
  doi     = {10.1016/j.bbalip.2021.158980},
  pmid    = {34044125},
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@article{alagarsamy2022-36077289,
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  title   = {{Apolipoprotein E in Cardiometabolic and Neurological Health and Diseases}},
  journal = {International journal of molecular sciences},
  year    = {2022},
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  pmid    = {36077289},
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@article{shinohara2023-37414536,
  author  = {Shinohara, Mitsuru and Gheni, Ghupurjan and Hitomi, Junichi and Bu, Guojun and Sato, Naoyuki},
  title   = {{APOE genotypes modify the obesity paradox in dementia}},
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  year    = {2023},
  doi     = {10.1136/jnnp-2022-331034},
  pmid    = {37414536},
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@article{kurano2022-34958030,
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  title   = {{Isoform-Dependent Effects of Apolipoprotein E on Sphingolipid Metabolism in Neural Cells}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2022},
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}

@article{moon2022-35041991,
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  title   = {{Human apolipoprotein E isoforms are differentially sialylated and the sialic acid moiety in ApoE2 attenuates ApoE2-Aβ interaction and Aβ fibrillation}},
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@article{mai2022-35582645,
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  title   = {{Molecular recognition of the interaction between ApoE and the TREM2 protein}},
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@article{stuchellbrereton2023-36749730,
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  title   = {{Apolipoprotein E4 has extensive conformational heterogeneity in lipid-free and lipid-bound forms}},
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@article{hu2021-34210002,
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  title   = {{Differential and substrate-specific inhibition of γ-secretase by the C-terminal region of ApoE2, ApoE3, and ApoE4}},
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  title   = {{Are apolipoprotein E fragments a promising new therapeutic target for Alzheimer's disease?}},
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@article{zhang2021-34530340,
  author  = {Zhang, Jing and Lin, Lanyan and Dai, Xiaoman and Xiao, Nai'an and Ye, Qinyong and Chen, Xiaochun},
  title   = {{ApoE4 increases susceptibility to stress-induced age-dependent depression-like behavior and cognitive impairment}},
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  year    = {2021},
  doi     = {10.1016/j.jpsychires.2021.09.029},
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  title   = {{APOE4 Affects Basal and NMDAR-Mediated Protein Synthesis in Neurons by Perturbing Calcium Homeostasis}},
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  year    = {2021},
  doi     = {10.1523/jneurosci.0435-21.2021},
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  title   = {{Amyloid β-Peptide Effects on Glucose Regulation Are Dependent on Apolipoprotein E Genotype}},
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@article{wooten2021-33138883,
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  title   = {{Apolipoprotein E (APOE) ε4 Status Moderates the Relationship Between Close-Range Blast Exposure and Cognitive Functioning}},
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@article{lv2023-37594184,
  author  = {Lv, Shuixin and Zhang, Yusi and Lin, Yingbin and Fang, Wenting and Wang, Yu and Li, Zihang and Lin, Anlan and Dai, Xiaoman and others},
  title   = {{ApoE4 exacerbates the senescence of hippocampal neurons and spatial cognitive impairment by downregulating acetyl-CoA level}},
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@article{chernyaeva2023-37155564,
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  title   = {{Reduced binding of apoE4 to complement factor H promotes amyloid-β oligomerization and neuroinflammation}},
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  year    = {2023},
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@article{hey2026-a02492d7,
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@article{lucas2026-9a749401,
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  title   = {{APOE Genotype and Fluid Biomarkers of Blood-Brain Barrier Integrity: A Systematic Review and Meta-Analysis}},
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@article{voloviceva2026-7b70684b,
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@article{wasef2026-1d706ebb,
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  title   = {{ApoE4 and Psychosis in Neurodegenerative and Non-Neurodegenerative Disease: A Scoping Review}},
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@article{muhammad2026-afc592dc,
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@article{shi2026-4dfb2d6c,
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  title   = {{Clinical utility of plasma APOE proteotyping for Alzheimer’s disease risk and prognosis}},
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@article{heidari2026-8aa9046f,
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  title   = {{APOE ε4 Carrier Status and Cognitive Decline in Mild-to-Moderate Alzheimer’s Disease: A Linear Mixed-Effects Analysis of the Placebo Arm of EXPEDITION 1}},
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  year    = {2026},
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@article{pallerla2026-922ec944,
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  title   = {{Anti-amyloid immunotherapy drives APOE4 specific increases in glial reactivity, perivascular immune activation, and ARIA-like events}},
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  title   = {{Plasma Proteomic Analysis of APOE ε4 Homozygotes Identifies Preclinical Alzheimer’s Disease Alterations Potentially Modulated by Semaglutide}},
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  title   = {{APOE4 reduction in vascular-associated fibroblasts decreases cerebral amyloid angiopathy and associated vascular dysfunction}},
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  title   = {{Ion modulation restores local synaptic function in APOE4 neuronal networks despite persistent impairments in global network organization}},
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  title   = {{Phenome-wide and proteomic analysis of APOE alleles across different ancestries in the All of Us Research Program}},
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  title   = {{Progressive behavioral and cognitive decline in Drosophila harboring AD- associated APOE4 variants}},
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  year    = {2026},
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