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% Source: https://alzhub.org/research?category=biomarkers&access=free
% 500 entries, in the order the page lists them. Built from alzhub.org's own records.
% 0 entries have no readable author in the source record and carry no author field.

@article{ashton2024-38252443,
  author  = {Ashton, N. J. and Brum, W. S. and Di Molfetta, G. and Benedet, A. L. and Arslan, B. and Jonaitis, E. and Langhough, R. E. and Cody, K. and Wilson, R. and Carlsson, C. M. and Vanmechelen, E. and Montoliu-Gaya, L. and others},
  title   = {{Diagnostic Accuracy of a Plasma Phosphorylated Tau 217 Immunoassay for Alzheimer Disease Pathology}},
  journal = {JAMA Neurology},
  year    = {2024},
  doi     = {10.1001/jamaneurol.2023.5319},
  pmid    = {38252443},
  url     = {https://doi.org/10.1001/jamaneurol.2023.5319}
}

@article{ossenkoppele2015-25988463,
  author  = {Ossenkoppele, R. and Jansen, W. J. and Rabinovici, G. D. and Knol, D. L. and van der Flier, W. M. and van Berckel, B. N. and Scheltens, P. and Visser, P. J. and others},
  title   = {{Prevalence of amyloid PET positivity in dementia syndromes: a meta-analysis}},
  journal = {JAMA},
  year    = {2015},
  doi     = {10.1001/jama.2015.4669},
  pmid    = {25988463},
  url     = {https://doi.org/10.1001/jama.2015.4669}
}

@article{pontecorvo2022-36251300,
  author  = {Pontecorvo, M. J. and Lu, M. and Burnham, S. C. and Schade, A. E. and Dage, J. L. and Shcherbinin, S. and Collins, E. C. and Sims, JR. and others},
  title   = {{Association of Donanemab Treatment With Exploratory Plasma Biomarkers in Early Symptomatic Alzheimer Disease: A Secondary Analysis of the TRAILBLAZER-ALZ Randomized Clinical Trial}},
  journal = {JAMA neurology},
  year    = {2022},
  doi     = {10.1001/jamaneurol.2022.3392},
  pmid    = {36251300},
  url     = {https://doi.org/10.1001/jamaneurol.2022.3392}
}

@article{olsson2016-27068280,
  author  = {Olsson, B. and Lautner, R. and Andreasson, U. and Öhrfelt, A. and Portelius, E. and Bjerke, M. and Hölttä, M. and Rosén, C. and others},
  title   = {{CSF and blood biomarkers for the diagnosis of Alzheimer's disease: a systematic review and meta-analysis}},
  journal = {The Lancet. Neurology},
  year    = {2016},
  doi     = {10.1016/s1474-4422(16)00070-3},
  pmid    = {27068280},
  url     = {https://doi.org/10.1016/s1474-4422(16)00070-3}
}

@article{warmenhoven2025-39468767,
  author  = {Warmenhoven, N. and Salvadó, G. and Janelidze, S. and Mattsson-Carlgren, N. and Bali, D. and Orduña Dolado, A. and Kolb, H. and Triana-Baltzer, G. and Barthélemy, N. R. and Schindler, S. E. and Aschenbrenner, A. J. and Raji, C. A. and others},
  title   = {{A comprehensive head-to-head comparison of key plasma phosphorylated tau 217 biomarker tests}},
  journal = {Brain},
  year    = {2025},
  doi     = {10.1093/brain/awae346},
  pmid    = {39468767},
  url     = {https://doi.org/10.1093/brain/awae346}
}

@article{ossenkoppele2025-40155777,
  author  = {Ossenkoppele, R. and Salvadó, G. and Janelidze, S. and Pichet Binette, A. and Bali, D. and Karlsson, L. and Palmqvist, S. and Mattsson-Carlgren, N. and Stomrud, E. and Therriault, J. and Rahmouni, N. and Rosa-Neto, P. and others},
  title   = {{Plasma p-tau217 and tau-PET predict future cognitive decline among cognitively unimpaired individuals: implications for clinical trials}},
  journal = {Nature Aging},
  year    = {2025},
  doi     = {10.1038/s43587-025-00835-z},
  pmid    = {40155777},
  url     = {https://doi.org/10.1038/s43587-025-00835-z}
}

@article{lu2024-39068543,
  author  = {Lu, Y. and Pike, JR. and Chen, J. and Walker, K. A. and Sullivan, K. J. and Thyagarajan, B. and Mielke, M. M. and Lutsey, P. L. and Knopman, D. and Gottesman, R. F. and Sharrett, A. R. and Coresh, J. and others},
  title   = {{Changes in Alzheimer Disease Blood Biomarkers and Associations With Incident All-Cause Dementia}},
  journal = {JAMA},
  year    = {2024},
  doi     = {10.1001/jama.2024.6619},
  pmid    = {39068543},
  url     = {https://doi.org/10.1001/jama.2024.6619}
}

@article{mattssoncarlgren2023-36745413,
  author  = {Mattsson-Carlgren, N. and Salvadó, G. and Ashton, N. J. and Tideman, P. and Stomrud, E. and Zetterberg, H. and Ossenkoppele, R. and Betthauser, T. J. and others},
  title   = {{Prediction of Longitudinal Cognitive Decline in Preclinical Alzheimer Disease Using Plasma Biomarkers}},
  journal = {JAMA neurology},
  year    = {2023},
  doi     = {10.1001/jamaneurol.2022.5272},
  pmid    = {36745413},
  url     = {https://doi.org/10.1001/jamaneurol.2022.5272}
}

@article{bateman2012-22784036,
  author  = {Bateman, Randall John and Xiong, Chengjie and Benzinger, Tammie L.S. and Fagan, Anne M. and Goate, Alison and Fox, Nick C. and Marcus, Daniel S. and Cairns, Nigel J. and others},
  title   = {{Clinical and Biomarker Changes in Dominantly Inherited Alzheimer's Disease}},
  journal = {New England Journal of Medicine},
  year    = {2012},
  doi     = {10.1056/nejmoa1202753},
  pmid    = {22784036},
  url     = {https://doi.org/10.1056/nejmoa1202753}
}

@article{brum2023-37653254,
  author  = {Brum, W. S. and Cullen, N. C. and Janelidze, S. and Ashton, N. J. and Zimmer, E. R. and Therriault, J. and Benedet, A. L. and Rahmouni, N. and Tissot, C. and Stevenson, J. and Servaes, S. and Triana-Baltzer, G. and others},
  title   = {{A two-step workflow based on plasma p-tau217 to screen for amyloid β positivity with further confirmatory testing only in uncertain cases}},
  journal = {Nature Aging},
  year    = {2023},
  doi     = {10.1038/s43587-023-00471-5},
  pmid    = {37653254},
  url     = {https://doi.org/10.1038/s43587-023-00471-5}
}

@article{mattssoncarlgren2024-38048096,
  author  = {Mattsson-Carlgren, N. and Collij, L. E. and Stomrud, E. and Pichet Binette, A. and Ossenkoppele, R. and Smith, R. and Karlsson, L. and Lantero-Rodriguez, J. and Snellman, A. and Strandberg, O. and Palmqvist, S. and Ashton, N. J. and others},
  title   = {{Plasma Biomarker Strategy for Selecting Patients With Alzheimer Disease for Antiamyloid Immunotherapies}},
  journal = {JAMA Neurology},
  year    = {2024},
  doi     = {10.1001/jamaneurol.2023.4596},
  pmid    = {38048096},
  url     = {https://doi.org/10.1001/jamaneurol.2023.4596}
}

@article{palmqvist2020-32722745,
  author  = {Palmqvist, S. and Janelidze, S. and Quiroz, Y. T. and Zetterberg, H. and Lopera, F. and Stomrud, E. and Su, Y. and Chen, Y. and others},
  title   = {{Discriminative Accuracy of Plasma Phospho-tau217 for Alzheimer Disease vs Other Neurodegenerative Disorders}},
  journal = {JAMA},
  year    = {2020},
  doi     = {10.1001/jama.2020.12134},
  pmid    = {32722745},
  url     = {https://doi.org/10.1001/jama.2020.12134}
}

@article{hanseeuw2019-31157827,
  author  = {Hanseeuw, B. J. and Betensky, R. A. and Jacobs, H. I. L. and Schultz, A. P. and Sepulcre, J. and Becker, J. A. and Cosio, D. M. O. and Farrell, M. and others},
  title   = {{Association of Amyloid and Tau With Cognition in Preclinical Alzheimer Disease: A Longitudinal Study}},
  journal = {JAMA neurology},
  year    = {2019},
  doi     = {10.1001/jamaneurol.2019.1424},
  pmid    = {31157827},
  url     = {https://doi.org/10.1001/jamaneurol.2019.1424}
}

@article{ossenkoppele2021-34180956,
  author  = {Ossenkoppele, R. and Smith, R. and Mattsson-Carlgren, N. and Groot, C. and Leuzy, A. and Strandberg, O. and Palmqvist, S. and Olsson, T. and others},
  title   = {{Accuracy of Tau Positron Emission Tomography as a Prognostic Marker in Preclinical and Prodromal Alzheimer Disease: A Head-to-Head Comparison Against Amyloid Positron Emission Tomography and Magnetic Resonance Imaging}},
  journal = {JAMA neurology},
  year    = {2021},
  doi     = {10.1001/jamaneurol.2021.1858},
  pmid    = {34180956},
  url     = {https://doi.org/10.1001/jamaneurol.2021.1858}
}

@article{janelidze2024-39068669,
  author  = {Janelidze, S. and Barthélemy, N. R. and Salvadó, G. and Schindler, S. E. and Palmqvist, S. and Mattsson-Carlgren, N. and Braunstein, J. B. and Ovod, V. and Bollinger, J. G. and He, Y. and Li, Y. and Raji, C. A. and others},
  title   = {{Plasma Phosphorylated Tau 217 and Aβ42/40 to Predict Early Brain Aβ Accumulation in People Without Cognitive Impairment}},
  journal = {JAMA Neurology},
  year    = {2024},
  doi     = {10.1001/jamaneurol.2024.2619},
  pmid    = {39068669},
  url     = {https://doi.org/10.1001/jamaneurol.2024.2619}
}

@article{mattsson2019-31009028,
  author  = {Mattsson, N. and Cullen, N. C. and Andreasson, U. and Zetterberg, H. and Blennow, K.},
  title   = {{Association Between Longitudinal Plasma Neurofilament Light and Neurodegeneration in Patients With Alzheimer Disease}},
  journal = {JAMA neurology},
  year    = {2019},
  doi     = {10.1001/jamaneurol.2019.0765},
  pmid    = {31009028},
  url     = {https://doi.org/10.1001/jamaneurol.2019.0765}
}

@article{rabinovici2019-30938796,
  author  = {Rabinovici, G. D. and Gatsonis, C. and Apgar, C. and Chaudhary, K. and Gareen, I. and Hanna, L. and Hendrix, J. and Hillner, B. E. and others},
  title   = {{Association of Amyloid Positron Emission Tomography With Subsequent Change in Clinical Management Among Medicare Beneficiaries With Mild Cognitive Impairment or Dementia}},
  journal = {JAMA},
  year    = {2019},
  doi     = {10.1001/jama.2019.2000},
  pmid    = {30938796},
  url     = {https://doi.org/10.1001/jama.2019.2000}
}

@article{lu2025-41082199,
  author  = {Lu, M. and Kim, M. J. and Collins, E. C. and Shcherbinin, S. and Ellinwood, A. K. and Yokoi, Y. and Brooks, D. A. and Hansson, O. and others},
  title   = {{Posttreatment Amyloid Levels and Clinical Outcomes Following Donanemab for Early Symptomatic Alzheimer Disease: A Secondary Analysis of the TRAILBLAZER-ALZ 2 Randomized Clinical Trial}},
  journal = {JAMA neurology},
  year    = {2025},
  doi     = {10.1001/jamaneurol.2025.3869},
  pmid    = {41082199},
  url     = {https://doi.org/10.1001/jamaneurol.2025.3869}
}

@article{mattsson2017-28346578,
  author  = {Mattsson, N. and Andreasson, U. and Zetterberg, H. and Blennow, K. and {Alzheimer’s Disease Neuroimaging Initiative}},
  title   = {{Association of Plasma Neurofilament Light With Neurodegeneration in Patients With Alzheimer Disease}},
  journal = {JAMA neurology},
  year    = {2017},
  doi     = {10.1001/jamaneurol.2016.6117},
  pmid    = {28346578},
  url     = {https://doi.org/10.1001/jamaneurol.2016.6117}
}

@article{benedet2021-34661615,
  author  = {Benedet, A. L. and Milà-Alomà, M. and Vrillon, A. and Ashton, N. J. and Pascoal, T. A. and Lussier, F. and Karikari, T. K. and Hourregue, C. and others},
  title   = {{Differences Between Plasma and Cerebrospinal Fluid Glial Fibrillary Acidic Protein Levels Across the Alzheimer Disease Continuum}},
  journal = {JAMA neurology},
  year    = {2021},
  doi     = {10.1001/jamaneurol.2021.3671},
  pmid    = {34661615},
  url     = {https://doi.org/10.1001/jamaneurol.2021.3671}
}

@article{janelidze2021-33165506,
  author  = {Janelidze, S. and Berron, D. and Smith, R. and Strandberg, O. and Proctor, N. K. and Dage, J. L. and Stomrud, E. and Palmqvist, S. and others},
  title   = {{Associations of Plasma Phospho-Tau217 Levels With Tau Positron Emission Tomography in Early Alzheimer Disease}},
  journal = {JAMA neurology},
  year    = {2021},
  doi     = {10.1001/jamaneurol.2020.4201},
  pmid    = {33165506},
  url     = {https://doi.org/10.1001/jamaneurol.2020.4201}
}

@article{moscoso2021-33427873,
  author  = {Moscoso, A. and Grothe, M. J. and Ashton, N. J. and Karikari, T. K. and Lantero Rodríguez, J. and Snellman, A. and Suárez-Calvet, M. and Blennow, K. and others},
  title   = {{Longitudinal Associations of Blood Phosphorylated Tau181 and Neurofilament Light Chain With Neurodegeneration in Alzheimer Disease}},
  journal = {JAMA neurology},
  year    = {2021},
  doi     = {10.1001/jamaneurol.2020.4986},
  pmid    = {33427873},
  url     = {https://doi.org/10.1001/jamaneurol.2020.4986}
}

@article{preische2019-30664784,
  author  = {Preische, O. and Schultz, S. A. and Apel, A. and Kuhle, J. and Kaeser, S. A. and Barro, C. and Gräber, S. and others},
  title   = {{Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer's disease}},
  journal = {Nature medicine},
  year    = {2019},
  doi     = {10.1038/s41591-018-0304-3},
  pmid    = {30664784},
  url     = {https://doi.org/10.1038/s41591-018-0304-3}
}

@article{barthelemy2024-38382645,
  author  = {Barthélemy, N. R. and Salvadó, G. and Schindler, S. E. and He, Y. and Janelidze, S. and Collij, L. E. and Saef, B. and Henson, R. L. and others},
  title   = {{Highly accurate blood test for Alzheimer's disease is similar or superior to clinical cerebrospinal fluid tests}},
  journal = {Nature medicine},
  year    = {2024},
  doi     = {10.1038/s41591-024-02869-z},
  pmid    = {38382645},
  url     = {https://doi.org/10.1038/s41591-024-02869-z}
}

@article{wilkins2022-36190710,
  author  = {Wilkins, C. H. and Windon, C. C. and Dilworth-Anderson, P. and Romanoff, J. and Gatsonis, C. and Hanna, L. and Apgar, C. and Gareen, I. F. and others},
  title   = {{Racial and Ethnic Differences in Amyloid PET Positivity in Individuals With Mild Cognitive Impairment or Dementia: A Secondary Analysis of the Imaging Dementia-Evidence for Amyloid Scanning (IDEAS) Cohort Study}},
  journal = {JAMA neurology},
  year    = {2022},
  doi     = {10.1001/jamaneurol.2022.3157},
  pmid    = {36190710},
  url     = {https://doi.org/10.1001/jamaneurol.2022.3157}
}

@article{sperling2024-39044488,
  author  = {Sperling, R. A. and Donohue, M. C. and Rissman, R. A. and Johnson, K. A. and Rentz, D. M. and Grill, J. D. and Heidebrink, J. L. and Jenkins, C. and others},
  title   = {{Amyloid and Tau Prediction of Cognitive and Functional Decline in Unimpaired Older Individuals: Longitudinal Data from the A4 and LEARN Studies}},
  journal = {The journal of prevention of Alzheimer's disease},
  year    = {2024},
  doi     = {10.14283/jpad.2024.122},
  pmid    = {39044488},
  url     = {https://doi.org/10.14283/jpad.2024.122}
}

@article{wagemann2024-38683602,
  author  = {Wagemann, O. and Liu, H. and Wang, G. and Shi, X. and Bittner, T. and Scelsi, M. A. and Farlow, M. R. and Clifford, D. B. and others},
  title   = {{Downstream Biomarker Effects of Gantenerumab or Solanezumab in Dominantly Inherited Alzheimer Disease: The DIAN-TU-001 Randomized Clinical Trial}},
  journal = {JAMA neurology},
  year    = {2024},
  doi     = {10.1001/jamaneurol.2024.0991},
  pmid    = {38683602},
  url     = {https://doi.org/10.1001/jamaneurol.2024.0991}
}

@article{altomare2023-37155177,
  author  = {Altomare, D. and Barkhof, F. and Caprioglio, C. and Collij, L. E. and Scheltens, P. and Lopes Alves, I. and Bouwman, F. and Berkhof, J. and others},
  title   = {{Clinical Effect of Early vs Late Amyloid Positron Emission Tomography in Memory Clinic Patients: The AMYPAD-DPMS Randomized Clinical Trial}},
  journal = {JAMA neurology},
  year    = {2023},
  doi     = {10.1001/jamaneurol.2023.0997},
  pmid    = {37155177},
  url     = {https://doi.org/10.1001/jamaneurol.2023.0997}
}

@article{mielke2025-39913137,
  author  = {Mielke, M. M. and Evans, J. K. and Neiberg, R. H. and Molina-Henry, D. P. and Marcovina, S. M. and Johnson, K. C. and Carmichael, O. T. and Rapp, SR. and others},
  title   = {{Alzheimer Disease Blood Biomarkers and Cognition Among Individuals With Diabetes and Overweight or Obesity}},
  journal = {JAMA network open},
  year    = {2025},
  doi     = {10.1001/jamanetworkopen.2024.58149},
  pmid    = {39913137},
  url     = {https://doi.org/10.1001/jamanetworkopen.2024.58149}
}

@article{mattssoncarlgren2026-41864233,
  author  = {Mattsson-Carlgren, Niklas and Palmqvist, Sebastian and Horie, Kanta and Barthélemy, Nicolas and Salvadó, Gemma and Binette, Alexa Pichet and Tideman, Pontus and Morris, John C and others},
  title   = {{Integration of plasma eMTBR-tau243 and p-tau217 in the diagnosis and stratification of Alzheimer's disease: a prospective cohort study}},
  journal = {The Lancet. Neurology},
  year    = {2026},
  doi     = {10.1016/S1474-4422(26)00029-3},
  pmid    = {41864233},
  url     = {https://doi.org/10.1016/S1474-4422(26)00029-3}
}

@article{salvado2025-40952756,
  author  = {Salvadó, G. and Janelidze, S. and Bali, D. and Dolado, A. O. and Therriault, J. and Brum, W. S. and Pichet Binette, A. and Stomrud, E. and Mattsson-Carlgren, N. and Palmqvist, S. and Coomans, E. M. and Teunissen, C. E. and others},
  title   = {{Plasma Phosphorylated Tau 217 to Identify Preclinical Alzheimer Disease}},
  journal = {JAMA Neurology},
  year    = {2025},
  doi     = {10.1001/jamaneurol.2025.3217},
  pmid    = {40952756},
  url     = {https://doi.org/10.1001/jamaneurol.2025.3217}
}

@article{cronje2023-37392405,
  author  = {Cronjé, H. T. and Liu, X. and Odden, M. C. and Moseholm, K. F. and Seshadri, S. and Satizabal, C. L. and Lopez, O. L. and Bis, J. C. and Djoussé, L. and Fohner, A. E. and Psaty, B. M. and Tracy, R. P. and others},
  title   = {{Serum NfL and GFAP are associated with incident dementia and dementia mortality in older adults: The cardiovascular health study}},
  journal = {Alzheimer's \& Dementia},
  year    = {2023},
  doi     = {10.1002/alz.13367},
  pmid    = {37392405},
  url     = {https://doi.org/10.1002/alz.13367}
}

@article{palmqvist2024-39068545,
  author  = {Palmqvist, S. and Tideman, P. and Mattsson-Carlgren, N. and Schindler, S. E. and Smith, R. and Ossenkoppele, R. and Calling, S. and West, T. and others},
  title   = {{Blood Biomarkers to Detect Alzheimer Disease in Primary Care and Secondary Care}},
  journal = {JAMA},
  year    = {2024},
  doi     = {10.1001/jama.2024.13855},
  pmid    = {39068545},
  url     = {https://doi.org/10.1001/jama.2024.13855}
}

@article{palmqvist2015-26354982,
  author  = {Palmqvist, S. and Zetterberg, H. and Mattsson, N. and Johansson, P. and {Alzheimer's Disease Neuroimaging Initiative} and Minthon, L. and Blennow, K. and Olsson, M. and others},
  title   = {{Detailed comparison of amyloid PET and CSF biomarkers for identifying early Alzheimer disease}},
  journal = {Neurology},
  year    = {2015},
  doi     = {10.1212/wnl.0000000000001991},
  pmid    = {26354982},
  url     = {https://doi.org/10.1212/wnl.0000000000001991}
}

@article{pase2019-30830207,
  author  = {Pase, M. P. and Beiser, A. S. and Himali, J. J. and Satizabal, C. L. and Aparicio, H. J. and DeCarli, C. and Chêne, G. and Dufouil, C. and others},
  title   = {{Assessment of Plasma Total Tau Level as a Predictive Biomarker for Dementia and Related Endophenotypes}},
  journal = {JAMA neurology},
  year    = {2019},
  doi     = {10.1001/jamaneurol.2018.4666},
  pmid    = {30830207},
  url     = {https://doi.org/10.1001/jamaneurol.2018.4666}
}

@article{leuzy2022-34928318,
  author  = {Leuzy, A. and Smith, R. and Cullen, N. C. and Strandberg, O. and Vogel, J. W. and Binette, A. P. and Borroni, E. and Janelidze, S. and others},
  title   = {{Biomarker-Based Prediction of Longitudinal Tau Positron Emission Tomography in Alzheimer Disease}},
  journal = {JAMA neurology},
  year    = {2022},
  doi     = {10.1001/jamaneurol.2021.4654},
  pmid    = {34928318},
  url     = {https://doi.org/10.1001/jamaneurol.2021.4654}
}

@article{benedict2020-31915189,
  author  = {Benedict, C. and Blennow, K. and Zetterberg, H. and Cedernaes, J.},
  title   = {{Effects of acute sleep loss on diurnal plasma dynamics of CNS health biomarkers in young men}},
  journal = {Neurology},
  year    = {2020},
  doi     = {10.1212/wnl.0000000000008866},
  pmid    = {31915189},
  url     = {https://doi.org/10.1212/wnl.0000000000008866}
}

@article{ashton2023-36877496,
  author  = {Ashton, N. J. and Moseby-Knappe, M. and Benedet, A. L. and Grötschel, L. and Lantero-Rodriguez, J. and Karikari, T. K. and Hassager, C. and Wise, M. P. and others},
  title   = {{Alzheimer Disease Blood Biomarkers in Patients With Out-of-Hospital Cardiac Arrest}},
  journal = {JAMA neurology},
  year    = {2023},
  doi     = {10.1001/jamaneurol.2023.0050},
  pmid    = {36877496},
  url     = {https://doi.org/10.1001/jamaneurol.2023.0050}
}

@article{fleisher2024-38386949,
  author  = {Fleisher, A. S. and Munsie, L. M. and Perahia, D. G. S. and Andersen, S. W. and Higgins, I. A. and Hauck, P. M. and Lo, A. C. and Sims, JR. and others},
  title   = {{Assessment of Efficacy and Safety of Zagotenemab: Results From PERISCOPE-ALZ, a Phase 2 Study in Early Symptomatic Alzheimer Disease}},
  journal = {Neurology},
  year    = {2024},
  doi     = {10.1212/wnl.0000000000208061},
  pmid    = {38386949},
  url     = {https://doi.org/10.1212/wnl.0000000000208061}
}

@article{holper2024-38986050,
  author  = {Holper, S. and Loveland, P. and Churilov, L. and Italiano, D. and Watson, R. and Yassi, N.},
  title   = {{Blood Astrocyte Biomarkers in Alzheimer Disease: A Systematic Review and Meta-Analysis}},
  journal = {Neurology},
  year    = {2024},
  doi     = {10.1212/wnl.0000000000209537},
  pmid    = {38986050},
  url     = {https://doi.org/10.1212/wnl.0000000000209537}
}

@article{malekahmadi2026-41324928,
  author  = {Malek-Ahmadi, M. and Sharma, S. and Stipho, F. and Denkinger, M. and Singh, A. and Brum, W. S. and Ashton, N. J.},
  title   = {{Plasma Phosphorylated Tau 217 and Amyloid Burden in Older Adults Without Cognitive Impairment: A Meta-Analysis}},
  journal = {JAMA neurology},
  year    = {2026},
  doi     = {10.1001/jamaneurol.2025.4721},
  pmid    = {41324928},
  url     = {https://doi.org/10.1001/jamaneurol.2025.4721}
}

@article{sun2026-41854616,
  author  = {Sun, Haoqi and Milton, Sasha and Fang, Yi and Taha, Hash Brown and Shiju, Shreya and Thomas, Robert J and Ganglberger, Wolfgang and Pase, Matthew P and others},
  title   = {{Machine Learning-Based Sleep Electroencephalographic Brain Age Index and Dementia Risk: An Individual Participant Data Meta-Analysis}},
  journal = {JAMA network open},
  year    = {2026},
  doi     = {10.1001/jamanetworkopen.2026.1521},
  pmid    = {41854616},
  url     = {https://doi.org/10.1001/jamanetworkopen.2026.1521}
}

@article{wang2025-40156286,
  author  = {Wang, J. and Huang, S. and Lan, G. and Lai, Y. J. and Wang, Q. H. and Chen, Y. and Xiao, Z. S. and Chen, X. and Bu, X. L. and Liu, Y. H. and Zeng, F. and Zhang, L. and others},
  title   = {{Diagnostic accuracy of plasma p-tau217/Aβ42 for Alzheimer's disease in clinical and community cohorts}},
  journal = {Alzheimer's \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz.70038},
  pmid    = {40156286},
  url     = {https://doi.org/10.1002/alz.70038}
}

@article{sanchezjuan2024-38634687,
  author  = {Sánchez-Juan, P. and Valeriano-Lorenzo, E. and Ruiz-González, A. and Pastor, A. B. and Rodrigo Lara, H. and López-González, F. and Zea-Sevilla, M. A. and Valentí, M. and Frades, B. and Ruiz, P. and Saiz, L. and Burgueño-García, I. and others},
  title   = {{Serum GFAP levels correlate with astrocyte reactivity, post-mortem brain atrophy and neurofibrillary tangles}},
  journal = {Brain},
  year    = {2024},
  doi     = {10.1093/brain/awae035},
  pmid    = {38634687},
  url     = {https://doi.org/10.1093/brain/awae035}
}

@article{palmqvist2019-31233127,
  author  = {Palmqvist, S. and Janelidze, S. and Stomrud, E. and Zetterberg, H. and Karl, J. and Zink, K. and Bittner, T. and Mattsson, N. and others},
  title   = {{Performance of Fully Automated Plasma Assays as Screening Tests for Alzheimer Disease-Related β-Amyloid Status}},
  journal = {JAMA neurology},
  year    = {2019},
  doi     = {10.1001/jamaneurol.2019.1632},
  pmid    = {31233127},
  url     = {https://doi.org/10.1001/jamaneurol.2019.1632}
}

@article{therriault2023-36508198,
  author  = {Therriault, J. and Vermeiren, M. and Servaes, S. and Tissot, C. and Ashton, N. J. and Benedet, A. L. and Karikari, T. K. and Lantero-Rodriguez, J. and others},
  title   = {{Association of Phosphorylated Tau Biomarkers With Amyloid Positron Emission Tomography vs Tau Positron Emission Tomography}},
  journal = {JAMA neurology},
  year    = {2023},
  doi     = {10.1001/jamaneurol.2022.4485},
  pmid    = {36508198},
  url     = {https://doi.org/10.1001/jamaneurol.2022.4485}
}

@article{lane2019-31444142,
  author  = {Lane, C. A. and Barnes, J. and Nicholas, J. M. and Sudre, C. H. and Cash, D. M. and Parker, T. D. and Malone, I. B. and Lu, K. and others},
  title   = {{Associations between blood pressure across adulthood and late-life brain structure and pathology in the neuroscience substudy of the 1946 British birth cohort (Insight 46): an epidemiological study}},
  journal = {The Lancet. Neurology},
  year    = {2019},
  doi     = {10.1016/s1474-4422(19)30228-5},
  pmid    = {31444142},
  url     = {https://doi.org/10.1016/s1474-4422(19)30228-5}
}

@article{jack2019-31501889,
  author  = {Jack, C. R. and Wiste, H. J. and Botha, H. and Weigand, S. D. and Therneau, T. M. and Knopman, D. S. and Graff-Radford, J. and Jones, D. T. and others},
  title   = {{The bivariate distribution of amyloid-β and tau: relationship with established neurocognitive clinical syndromes}},
  journal = {Brain : a journal of neurology},
  year    = {2019},
  doi     = {10.1093/brain/awz268},
  pmid    = {31501889},
  url     = {https://doi.org/10.1093/brain/awz268}
}

@article{raghavan2020-32568366,
  author  = {Raghavan, N. S. and Dumitrescu, L. and Mormino, E. and Mahoney, E. R. and Lee, A. J. and Gao, Y. and Bilgel, M. and Goldstein, D. and others},
  title   = {{Association Between Common Variants in RBFOX1, an RNA-Binding Protein, and Brain Amyloidosis in Early and Preclinical Alzheimer Disease}},
  journal = {JAMA neurology},
  year    = {2020},
  doi     = {10.1001/jamaneurol.2020.1760},
  pmid    = {32568366},
  url     = {https://doi.org/10.1001/jamaneurol.2020.1760}
}

@article{petersen2026-41714746,
  author  = {Petersen, Kellen K and Milà-Alomà, Marta and Li, Yan and Du, Lianlian and Xiong, Chengjie and Tosun, Duygu and Saef, Benjamin and Saad, Ziad S and others},
  title   = {{Predicting onset of symptomatic Alzheimer's disease with plasma p-tau217 clocks}},
  journal = {Nature medicine},
  year    = {2026},
  doi     = {10.1038/s41591-026-04206-y},
  pmid    = {41714746},
  url     = {https://doi.org/10.1038/s41591-026-04206-y}
}

@article{yakoub2025-40008832,
  author  = {Yakoub, Y. and Gonzalez-Ortiz, F. and Ashton, N. J. and Déry, C. and Strikwerda-Brown, C. and St-Onge, F. and Ourry, V. and Schöll, M. and Geddes, M. R. and Ducharme, S. and Montembeault, M. and Rosa-Neto, P. and others},
  title   = {{Plasma p-tau217 identifies cognitively normal older adults who will develop cognitive impairment in a 10-year window}},
  journal = {Alzheimer's \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz.14537},
  pmid    = {40008832},
  url     = {https://doi.org/10.1002/alz.14537}
}

@article{jack2019-31211344,
  author  = {Jack, C. R. and Wiste, H. J. and Therneau, T. M. and Weigand, S. D. and Knopman, D. S. and Mielke, M. M. and Lowe, V. J. and Vemuri, P. and others},
  title   = {{Associations of Amyloid, Tau, and Neurodegeneration Biomarker Profiles With Rates of Memory Decline Among Individuals Without Dementia}},
  journal = {JAMA},
  year    = {2019},
  doi     = {10.1001/jama.2019.7437},
  pmid    = {31211344},
  url     = {https://doi.org/10.1001/jama.2019.7437}
}

@article{jansen2022-35099509,
  author  = {Jansen, W. J. and Janssen, O. and Tijms, B. M. and Vos, S. J. B. and Ossenkoppele, R. and Visser, P. J. and {Amyloid Biomarker Study Group} and Aarsland, D. and others},
  title   = {{Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum}},
  journal = {JAMA neurology},
  year    = {2022},
  doi     = {10.1001/jamaneurol.2021.5216},
  pmid    = {35099509},
  url     = {https://doi.org/10.1001/jamaneurol.2021.5216}
}

@article{jack2019-31305929,
  author  = {Jack, C. R. and Therneau, T. M. and Weigand, S. D. and Wiste, H. J. and Knopman, D. S. and Vemuri, P. and Lowe, V. J. and Mielke, M. M. and others},
  title   = {{Prevalence of Biologically vs Clinically Defined Alzheimer Spectrum Entities Using the National Institute on Aging-Alzheimer's Association Research Framework}},
  journal = {JAMA neurology},
  year    = {2019},
  doi     = {10.1001/jamaneurol.2019.1971},
  pmid    = {31305929},
  url     = {https://doi.org/10.1001/jamaneurol.2019.1971}
}

@article{hu2022-35446396,
  author  = {Hu, Y. and Kirmess, K. M. and Meyer, M. R. and Rabinovici, G. D. and Gatsonis, C. and Siegel, B. A. and Whitmer, R. A. and Apgar, C. and others},
  title   = {{Assessment of a Plasma Amyloid Probability Score to Estimate Amyloid Positron Emission Tomography Findings Among Adults With Cognitive Impairment}},
  journal = {JAMA network open},
  year    = {2022},
  doi     = {10.1001/jamanetworkopen.2022.8392},
  pmid    = {35446396},
  url     = {https://doi.org/10.1001/jamanetworkopen.2022.8392}
}

@article{stocker2023-36692879,
  author  = {Stocker, H. and Beyer, L. and Trares, K. and Perna, L. and Rujescu, D. and Holleczek, B. and Beyreuther, K. and Gerwert, K. and others},
  title   = {{Association of Kidney Function With Development of Alzheimer Disease and Other Dementias and Dementia-Related Blood Biomarkers}},
  journal = {JAMA network open},
  year    = {2023},
  doi     = {10.1001/jamanetworkopen.2022.52387},
  pmid    = {36692879},
  url     = {https://doi.org/10.1001/jamanetworkopen.2022.52387}
}

@article{planche2023-36261295,
  author  = {Planche, V. and Bouteloup, V. and Pellegrin, I. and Mangin, J. F. and Dubois, B. and Ousset, P. J. and Pasquier, F. and Blanc, F. and others},
  title   = {{Validity and Performance of Blood Biomarkers for Alzheimer Disease to Predict Dementia Risk in a Large Clinic-Based Cohort}},
  journal = {Neurology},
  year    = {2023},
  doi     = {10.1212/wnl.0000000000201479},
  pmid    = {36261295},
  url     = {https://doi.org/10.1212/wnl.0000000000201479}
}

@article{bouteloup2025-40181683,
  author  = {Bouteloup, V. and Villain, N. and Vidal, J. S. and Gonzalez-Ortiz, F. and Yuksekel, I. and Santos, C. and Schraen-Maschken, S. and Pellegrin, I. and others},
  title   = {{Cognitive Phenotyping and Interpretation of Alzheimer Blood Biomarkers}},
  journal = {JAMA neurology},
  year    = {2025},
  doi     = {10.1001/jamaneurol.2025.0142},
  pmid    = {40181683},
  url     = {https://doi.org/10.1001/jamaneurol.2025.0142}
}

@article{sanchez2025-40063856,
  author  = {Sanchez, E. and Coughlan, G. T. and Wilkinson, T. and Ramirez, J. and Mirza, S. S. and Baril, A. A. and Dilliott, A. A. and Frank, A. and others},
  title   = {{Association of Plasma Biomarkers With Longitudinal Atrophy and Microvascular Burden on MRI Across Neurodegenerative and Cerebrovascular Diseases}},
  journal = {Neurology},
  year    = {2025},
  doi     = {10.1212/wnl.0000000000213438},
  pmid    = {40063856},
  url     = {https://doi.org/10.1212/wnl.0000000000213438}
}

@article{gonzalezortiz2025-40373247,
  author  = {Gonzalez-Ortiz, F. and Kirsebom, B. E. and Yakoub, Y. and Gundersen, J. K. and Pålhaugen, L. and Waterloo, K. and Selnes, P. and Jarholm, J. A. and others},
  title   = {{Associations Between Changes in Levels of Phosphorylated Tau and Severity of Cognitive Impairment in Early Alzheimer Disease}},
  journal = {Neurology},
  year    = {2025},
  doi     = {10.1212/wnl.0000000000213676},
  pmid    = {40373247},
  url     = {https://doi.org/10.1212/wnl.0000000000213676}
}

@article{cantoni2025-41359335,
  author  = {Cantoni, V. and Casula, E. P. and Tarantino, B. and Cupidi, C. and Huber, N. and Altomare, D. and Premi, E. and Zummo, E. and others},
  title   = {{Home-Based Gamma Transcranial Alternating Current Stimulation in Patients With Alzheimer Disease: A Randomized Clinical Trial}},
  journal = {JAMA network open},
  year    = {2025},
  doi     = {10.1001/jamanetworkopen.2025.46556},
  pmid    = {41359335},
  url     = {https://doi.org/10.1001/jamanetworkopen.2025.46556}
}

@article{shadyab2026-41805953,
  author  = {Shadyab, A. H. and Zhang, B. and LaCroix, A. Z. and Mielke, M. M. and Resnick, S. M. and Nguyen, S. and Ferrucci, L. and Libermann, T. A. and Ngo, L. and Casanova, R. and others},
  title   = {{Plasma Phosphorylated Tau 217 and Incident Mild Cognitive Impairment and Dementia in Older Women}},
  journal = {JAMA Network Open},
  year    = {2026},
  doi     = {10.1001/jamanetworkopen.2026.1295},
  pmid    = {41805953},
  url     = {https://doi.org/10.1001/jamanetworkopen.2026.1295}
}

@article{insel2025-40853684,
  author  = {Insel, P. S. and Mattsson-Carlgren, N. and Langford, O. and Caruso, V. M. and Leuzy, A. and Young, C. B. and Boxer, A. and Aisen, P. S. and Sperling, R. A. and Mormino, E. C. and Donohue, M. C.},
  title   = {{Concurrent Changes in Plasma Phosphorylated Tau 217, Tau PET, and Cognition in Preclinical Alzheimer Disease}},
  journal = {JAMA Neurology},
  year    = {2025},
  doi     = {10.1001/jamaneurol.2025.2974},
  pmid    = {40853684},
  url     = {https://doi.org/10.1001/jamaneurol.2025.2974}
}

@article{bornhorst2025-39823562,
  author  = {Bornhorst, J. A. and Lundgreen, C. S. and Weigand, S. D. and Figdore, D. J. and Wiste, H. and Griswold, M. and Vemuri, P. and Graff-Radford, J. and Knopman, D. S. and Cogswell, P. and Jack, C. R. and Petersen, R. C. and others},
  title   = {{Quantitative Assessment of the Effect of Chronic Kidney Disease on Plasma P-Tau217 Concentrations}},
  journal = {Neurology},
  year    = {2025},
  doi     = {10.1212/WNL.0000000000210287},
  pmid    = {39823562},
  url     = {https://doi.org/10.1212/WNL.0000000000210287}
}

@article{bridel2019-31206160,
  author  = {Bridel, C. and van Wieringen, W. N. and Zetterberg, H. and Tijms, B. M. and Teunissen, C. E. and {the NFL Group} and Alvarez-Cermeño, J. C. and Andreasson, U. and others},
  title   = {{Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology: A Systematic Review and Meta-analysis}},
  journal = {JAMA neurology},
  year    = {2019},
  doi     = {10.1001/jamaneurol.2019.1534},
  pmid    = {31206160},
  url     = {https://doi.org/10.1001/jamaneurol.2019.1534}
}

@article{janelidze2023-36987840,
  author  = {Janelidze, S. and Barthélemy, N. R. and He, Y. and Bateman, R. J. and Hansson, O.},
  title   = {{Mitigating the Associations of Kidney Dysfunction With Blood Biomarkers of Alzheimer Disease by Using Phosphorylated Tau to Total Tau Ratios}},
  journal = {JAMA neurology},
  year    = {2023},
  doi     = {10.1001/jamaneurol.2023.0199},
  pmid    = {36987840},
  url     = {https://doi.org/10.1001/jamaneurol.2023.0199}
}

@article{jabbari2020-31860007,
  author  = {Jabbari, E. and Holland, N. and Chelban, V. and Jones, P. S. and Lamb, R. and Rawlinson, C. and Guo, T. and Costantini, A. A. and others},
  title   = {{Diagnosis Across the Spectrum of Progressive Supranuclear Palsy and Corticobasal Syndrome}},
  journal = {JAMA neurology},
  year    = {2020},
  doi     = {10.1001/jamaneurol.2019.4347},
  pmid    = {31860007},
  url     = {https://doi.org/10.1001/jamaneurol.2019.4347}
}

@article{coughlan2026-41697669,
  author  = {Coughlan, Gillian T and Ourry, Valentin and Townsend, Diana and Klinger, Hannah and Brown, Jane A and Cuppels, Madison and Betthauser, Tobey and Langhough, Rebecca and others},
  title   = {{Sex Differences in P-Tau217, Tau Aggregation, and Cognitive Decline}},
  journal = {JAMA neurology},
  year    = {2026},
  doi     = {10.1001/jamaneurol.2025.5670},
  pmid    = {41697669},
  url     = {https://doi.org/10.1001/jamaneurol.2025.5670}
}

@article{gasparini2026-41337685,
  author  = {Gasparini, F. and Valletta, M. and Vetrano, D. L. and Beridze, G. and Rizzuto, D. and Calderón-Larrañaga, A. and Fredolini, C. and Dale, M. and Winblad, B. and Fratiglioni, L. and Grande, G.},
  title   = {{Kidney Function, Alzheimer Disease Blood Biomarkers, and Dementia Risk in Community-Dwelling Older Adults}},
  journal = {Neurology},
  year    = {2026},
  doi     = {10.1212/WNL.0000000000214446},
  pmid    = {41337685},
  url     = {https://doi.org/10.1212/WNL.0000000000214446}
}

@article{salvado2026-42189519,
  author  = {Salvadó, G. and Horie, K. and Barthélemy, N. R. and Schindler, S. E. and Janelidze, S. and Orduña Dolado, A. and Bali, D. and Perrin, R. J. and Morris, J. C. and Benzinger, T. L. S. and Gordon, B. A. and Stomrud, E. and others},
  title   = {{Plasma eMTBR-tau243 and \%p-tau217 for Biological Staging of Alzheimer Disease}},
  journal = {JAMA Neurology},
  year    = {2026},
  doi     = {10.1001/jamaneurol.2026.1405},
  pmid    = {42189519},
  url     = {https://doi.org/10.1001/jamaneurol.2026.1405}
}

@article{sperling2020-32250387,
  author  = {Sperling, R. A. and Donohue, M. C. and Raman, R. and Sun, C. K. and Yaari, R. and Holdridge, K. and Siemers, E. and Johnson, K. A. and others},
  title   = {{Association of Factors With Elevated Amyloid Burden in Clinically Normal Older Individuals}},
  journal = {JAMA neurology},
  year    = {2020},
  doi     = {10.1001/jamaneurol.2020.0387},
  pmid    = {32250387},
  url     = {https://doi.org/10.1001/jamaneurol.2020.0387}
}

@article{aschenbrenner2018-30068637,
  author  = {Aschenbrenner, A. J. and Gordon, B. A. and Benzinger, T. L. S. and Morris, J. C. and Hassenstab, J. J.},
  title   = {{Influence of tau PET, amyloid PET, and hippocampal volume on cognition in Alzheimer disease}},
  journal = {Neurology},
  year    = {2018},
  doi     = {10.1212/wnl.0000000000006075},
  pmid    = {30068637},
  url     = {https://doi.org/10.1212/wnl.0000000000006075}
}

@article{cicognola2021-33773595,
  author  = {Cicognola, C. and Janelidze, S. and Hertze, J. and Zetterberg, H. and Blennow, K. and Mattsson-Carlgren, N. and Hansson, O.},
  title   = {{Plasma glial fibrillary acidic protein detects Alzheimer pathology and predicts future conversion to Alzheimer dementia in patients with mild cognitive impairment}},
  journal = {Alzheimer's research \& therapy},
  year    = {2021},
  doi     = {10.1186/s13195-021-00804-9},
  pmid    = {33773595},
  url     = {https://doi.org/10.1186/s13195-021-00804-9}
}

@article{olsson2019-30508027,
  author  = {Olsson, B. and Portelius, E. and Cullen, N. C. and Å, Sandelius and Zetterberg, H. and Andreasson, U. and Höglund, K. and Irwin, D. J. and others},
  title   = {{Association of Cerebrospinal Fluid Neurofilament Light Protein Levels With Cognition in Patients With Dementia, Motor Neuron Disease, and Movement Disorders}},
  journal = {JAMA neurology},
  year    = {2019},
  doi     = {10.1001/jamaneurol.2018.3746},
  pmid    = {30508027},
  url     = {https://doi.org/10.1001/jamaneurol.2018.3746}
}

@article{collij2020-32675080,
  author  = {Collij, L. E. and Heeman, F. and Salvadó, G. and Ingala, S. and Altomare, D. and de Wilde, A. and Konijnenberg, E. and van Buchem, M. and others},
  title   = {{Multitracer model for staging cortical amyloid deposition using PET imaging}},
  journal = {Neurology},
  year    = {2020},
  doi     = {10.1212/wnl.0000000000010256},
  pmid    = {32675080},
  url     = {https://doi.org/10.1212/wnl.0000000000010256}
}

@article{therriault2021-33443136,
  author  = {Therriault, J. and Pascoal, T. A. and Benedet, A. L. and Tissot, C. and Savard, M. and Chamoun, M. and Lussier, F. and Kang, M. S. and others},
  title   = {{Frequency of Biologically Defined Alzheimer Disease in Relation to Age, Sex, APOE ε4, and Cognitive Impairment}},
  journal = {Neurology},
  year    = {2021},
  doi     = {10.1212/wnl.0000000000011416},
  pmid    = {33443136},
  url     = {https://doi.org/10.1212/wnl.0000000000011416}
}

@article{dittrich2023-37225431,
  author  = {Dittrich, A. and Ashton, N. J. and Zetterberg, H. and Blennow, K. and Zettergren, A. and Simrén, J. and Skillbäck, T. and Shams, S. and others},
  title   = {{Association of Chronic Kidney Disease With Plasma NfL and Other Biomarkers of Neurodegeneration: The H70 Birth Cohort Study in Gothenburg}},
  journal = {Neurology},
  year    = {2023},
  doi     = {10.1212/wnl.0000000000207419},
  pmid    = {37225431},
  url     = {https://doi.org/10.1212/wnl.0000000000207419}
}

@article{bolsewig2024-38830138,
  author  = {Bolsewig, K. and van Unnik, A. A. J. M. and Blujdea, E. R. and Gonzalez, M. C. and Ashton, N. J. and Aarsland, D. and Zetterberg, H. and Padovani, A. and others},
  title   = {{Association of Plasma Amyloid, P-Tau, GFAP, and NfL With CSF, Clinical, and Cognitive Features in Patients With Dementia With Lewy Bodies}},
  journal = {Neurology},
  year    = {2024},
  doi     = {10.1212/wnl.0000000000209418},
  pmid    = {38830138},
  url     = {https://doi.org/10.1212/wnl.0000000000209418}
}

@article{pichetbinette2025-40388185,
  author  = {Pichet Binette, A. and Smith, R. and Salvadó, G. and Tideman, P. and Glans, I. and van Westen, D. and Groot, C. and Ossenkoppele, R. and others},
  title   = {{Evaluation of the Revised Criteria for Biological and Clinical Staging of Alzheimer Disease}},
  journal = {JAMA neurology},
  year    = {2025},
  doi     = {10.1001/jamaneurol.2025.1100},
  pmid    = {40388185},
  url     = {https://doi.org/10.1001/jamaneurol.2025.1100}
}

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@article{valletta2026-41996117,
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  title   = {{Plasma neurofilament light chain in the presenilin 1 E280A autosomal dominant Alzheimer's disease kindred: a cross-sectional and longitudinal cohort study}},
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  title   = {{Spatial-Temporal Patterns of β-Amyloid Accumulation: A Subtype and Stage Inference Model Analysis}},
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  year    = {2022},
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  pmid    = {35292558},
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@article{rojas2018-29282336,
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  title   = {{CSF neurofilament light chain and phosphorylated tau 181 predict disease progression in PSP}},
  journal = {Neurology},
  year    = {2018},
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  pmid    = {29282336},
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@article{schindler2021-34504028,
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  title   = {{Predicting Symptom Onset in Sporadic Alzheimer Disease With Amyloid PET}},
  journal = {Neurology},
  year    = {2021},
  doi     = {10.1212/wnl.0000000000012775},
  pmid    = {34504028},
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@article{young2022-35435938,
  author  = {Young, C. B. and Winer, JR. and Younes, K. and Cody, K. A. and Betthauser, T. J. and Johnson, S. C. and Schultz, A. and Sperling, R. A. and others},
  title   = {{Divergent Cortical Tau Positron Emission Tomography Patterns Among Patients With Preclinical Alzheimer Disease}},
  journal = {JAMA neurology},
  year    = {2022},
  doi     = {10.1001/jamaneurol.2022.0676},
  pmid    = {35435938},
  url     = {https://doi.org/10.1001/jamaneurol.2022.0676}
}

@article{cicognola2023-37137722,
  author  = {Cicognola, C. and Mattsson-Carlgren, N. and van Westen, D. and Zetterberg, H. and Blennow, K. and Palmqvist, S. and Ahmadi, K. and Strandberg, O. and others},
  title   = {{Associations of CSF PDGFRβ With Aging, Blood-Brain Barrier Damage, Neuroinflammation, and Alzheimer Disease Pathologic Changes}},
  journal = {Neurology},
  year    = {2023},
  doi     = {10.1212/wnl.0000000000207358},
  pmid    = {37137722},
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@article{hofmann2024-39557867,
  author  = {Hofmann, A. and Häsler, L. M. and Lambert, M. and Kaeser, S. A. and Gräber-Sultan, S. and Obermüller, U. and Kuder-Buletta, E. and la Fougere, C. and others},
  title   = {{Comparative neurofilament light chain trajectories in CSF and plasma in autosomal dominant Alzheimer's disease}},
  journal = {Nature communications},
  year    = {2024},
  doi     = {10.1038/s41467-024-52937-8},
  pmid    = {39557867},
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@article{zeltzer2025-40720133,
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  title   = {{Concordance Between Amyloid-PET Quantification and Real-World Visual Reads}},
  journal = {JAMA neurology},
  year    = {2025},
  doi     = {10.1001/jamaneurol.2025.2218},
  pmid    = {40720133},
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}

@article{vanderveere2024-38986053,
  author  = {van der Veere, P. J. and Hoogland, J. and Visser, L. N. C. and Van Harten, A. C. and Rhodius-Meester, H. F. and Sikkes, S. A. M. and Venkatraghavan, V. and Barkhof, F. and others},
  title   = {{Predicting Cognitive Decline in Amyloid-Positive Patients With Mild Cognitive Impairment or Mild Dementia}},
  journal = {Neurology},
  year    = {2024},
  doi     = {10.1212/wnl.0000000000209605},
  pmid    = {38986053},
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@article{kim2025-40042844,
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  title   = {{Physical Activity, Alzheimer Plasma Biomarkers, and Cognition}},
  journal = {JAMA network open},
  year    = {2025},
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@article{honig2024-38377442,
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  title   = {{Association Between Years of Education and Amyloid Burden in Patients With Subjective Cognitive Decline, MCI, and Alzheimer Disease}},
  journal = {Neurology},
  year    = {2024},
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  pmid    = {38377442},
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@article{davidson2026-41109840,
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  title   = {{Effect of obicetrapib, a potent cholesteryl ester transfer protein inhibitor, on p-tau217 levels in patients with cardiovascular disease}},
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  year    = {2026},
  doi     = {10.1016/j.tjpad.2025.100394},
  pmid    = {41109840},
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@article{delrieu2023-37872582,
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  title   = {{Cognitive impact of multidomain intervention and omega 3 according to blood Aβ42/40 ratio: a subgroup analysis from the randomized MAPT trial}},
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  pmid    = {37872582},
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@article{yim2025-40829110,
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  title   = {{Integrating MRI Volume and Plasma p-Tau217 for Amyloid Risk Stratification in Early-Stage Alzheimer Disease}},
  journal = {Neurology},
  year    = {2025},
  doi     = {10.1212/wnl.0000000000213954},
  pmid    = {40829110},
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@article{karlsson2025-41051312,
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  title   = {{Reference proteins to improve Core 1 and Core 2 Alzheimer’s disease CSF and plasma biomarkers}},
  journal = {Brain},
  year    = {2025},
  doi     = {10.1093/brain/awaf375},
  pmid    = {41051312},
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@article{schindler2024-38866966,
  author  = {Schindler, S. E. and Galasko, D. and Pereira, A. C. and Rabinovici, G. D. and Salloway, S. and Suárez-Calvet, M. and Khachaturian, A. S. and Mielke, M. M. and Udeh-Momoh, C. and Weiss, J. and Batrla, R. and Bozeat, S. and others},
  title   = {{Acceptable performance of blood biomarker tests of amyloid pathology - recommendations from the Global CEO Initiative on Alzheimer's Disease}},
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  year    = {2024},
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@article{piura2025-40476540,
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  title   = {{Diagnostic performance of plasma p-tau217 and Aβ42/40 biomarkers in the outpatient memory clinic}},
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  year    = {2025},
  doi     = {10.1002/alz.70316},
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@article{schindler2019-31371569,
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  year    = {2019},
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@article{taddei2023-37812432,
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  title   = {{Tau Oligomer-Containing Synapse Elimination by Microglia and Astrocytes in Alzheimer Disease}},
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  year    = {2023},
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  pmid    = {37812432},
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@article{iaccarino2021-33252608,
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  title   = {{Association Between Ambient Air Pollution and Amyloid Positron Emission Tomography Positivity in Older Adults With Cognitive Impairment}},
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  year    = {2021},
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  pmid    = {33252608},
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@article{hajjar2022-36201209,
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  title   = {{Association of Plasma and Cerebrospinal Fluid Alzheimer Disease Biomarkers With Race and the Role of Genetic Ancestry, Vascular Comorbidities, and Neighborhood Factors}},
  journal = {JAMA network open},
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@article{fagan2021-34302786,
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  title   = {{Comparison of CSF biomarkers in Down syndrome and autosomal dominant Alzheimer's disease: a cross-sectional study}},
  journal = {The Lancet. Neurology},
  year    = {2021},
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  title   = {{Impact of Reference and Target Region Selection on Amyloid PET SUV Ratios in the Phase 1b PRIME Study of Aducanumab}},
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  year    = {2019},
  doi     = {10.2967/jnumed.118.209130},
  pmid    = {29777003},
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@article{kivisakk2022-35800899,
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  title   = {{Plasma biomarkers for prognosis of cognitive decline in patients with mild cognitive impairment}},
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  year    = {2022},
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@article{kang2025-40343697,
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  title   = {{Cerebral Amyloid Angiopathy and Downstream Alzheimer Disease Plasma Biomarkers}},
  journal = {JAMA network open},
  year    = {2025},
  doi     = {10.1001/jamanetworkopen.2025.8842},
  pmid    = {40343697},
  url     = {https://doi.org/10.1001/jamanetworkopen.2025.8842}
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@article{cai2025-40622710,
  author  = {Cai, Yue Qin and Fang, Lili and Yang, Jie and Zhou, Xin Yu and Liu, Lin and Li, Anqi and Sun, Pan and Lan, Guoyu and others},
  title   = {{Higher Educational Attainment and Accelerated Tau Accumulation in Alzheimer Disease}},
  journal = {JAMA Neurology},
  year    = {2025},
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  pmid    = {40622710},
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@article{mattssoncarlgren2022-35173015,
  author  = {Mattsson-Carlgren, N. and Grinberg, L. T. and Boxer, A. and Ossenkoppele, R. and Jonsson, M. and Seeley, W. and Ehrenberg, A. and Spina, S. and others},
  title   = {{Cerebrospinal Fluid Biomarkers in Autopsy-Confirmed Alzheimer Disease and Frontotemporal Lobar Degeneration}},
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  year    = {2022},
  doi     = {10.1212/wnl.0000000000200040},
  pmid    = {35173015},
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@article{leuzy2021-34493616,
  author  = {Leuzy, A. and Janelidze, S. and Mattsson-Carlgren, N. and Palmqvist, S. and Jacobs, D. and Cicognola, C. and Stomrud, E. and Vanmechelen, E. and others},
  title   = {{Comparing the Clinical Utility and Diagnostic Performance of CSF P-Tau181, P-Tau217, and P-Tau231 Assays}},
  journal = {Neurology},
  year    = {2021},
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  pmid    = {34493616},
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@article{brickman2018-30217936,
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  title   = {{An MRI measure of degenerative and cerebrovascular pathology in Alzheimer disease}},
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@article{dark2025-39889254,
  author  = {Dark, Heather E. and Shafer, Andrea T. and Cordon, Jenifer and An, Yang and Lewis, Alexandria and Moghekar, Abhay and Landman, Bennett A. and Resnick, Susan M. and others},
  title   = {{Association of Plasma Biomarkers of Alzheimer Disease and Neurodegeneration With Longitudinal Intra-Network Functional Brain Connectivity}},
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  year    = {2025},
  doi     = {10.1212/wnl.0000000000210271},
  pmid    = {39889254},
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@article{sewell2026-41980229,
  author  = {Sewell, Kelsey R. and Solis‐Urra, Patricio and Huang, Haiqing and Karikari, Thomas K. and Grove, George and Kramer, Arthur F. and McAuley, Edward and Burns, Jeffrey Murray and others},
  title   = {{Cognitive and Brain Reserve as Modifiers of Early Alzheimer Disease–Related Cognitive Vulnerability}},
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  year    = {2013},
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@article{lajoie2021-33262228,
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  title   = {{Association of APOE4 and Clinical Variability in Alzheimer Disease With the Pattern of Tau- and Amyloid-PET}},
  journal = {Neurology},
  year    = {2021},
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@article{ramanan2023-37580163,
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  title   = {{Association of Plasma Biomarkers of Alzheimer Disease With Cognition and Medical Comorbidities in a Biracial Cohort}},
  journal = {Neurology},
  year    = {2023},
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@article{grothe2021-34266917,
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  title   = {{Associations of Fully Automated CSF and Novel Plasma Biomarkers With Alzheimer Disease Neuropathology at Autopsy}},
  journal = {Neurology},
  year    = {2021},
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@article{boerwinkle2023-36517172,
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  title   = {{Comparison of amyloid burden in individuals with Down syndrome versus autosomal dominant Alzheimer's disease: a cross-sectional study}},
  journal = {The Lancet. Neurology},
  year    = {2023},
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@article{honig2023-37079306,
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  title   = {{Evaluation of Plasma Biomarkers for A/T/N Classification of Alzheimer Disease Among Adults of Caribbean Hispanic Ethnicity}},
  journal = {JAMA network open},
  year    = {2023},
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  title   = {{Evaluation of ATNPD Framework and Biofluid Markers to Predict Cognitive Decline in Early Parkinson Disease}},
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@article{hazan2024-39353147,
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  title   = {{Challenges in a Biological Definition of Alzheimer Disease}},
  journal = {Neurology},
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@article{gomar2024-38922609,
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@article{li2023-38019518,
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  title   = {{Plasma Biomarkers of Alzheimer Disease in Women With and Without HIV}},
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@article{shrestha2025-40373252,
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  title   = {{Olfaction and Plasma Biomarkers of Alzheimer Disease and Neurodegeneration in the Atherosclerosis Risk in Communities Study}},
  journal = {Neurology},
  year    = {2025},
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@article{liang2025-39836940,
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  title   = {{Association of Polygenic Risk Score for 5 Diseases With Alzheimer Disease Progression, Biomarkers, and Amyloid Deposition}},
  journal = {Neurology},
  year    = {2025},
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@article{hansson2022-35908251,
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  title   = {{The Alzheimer's Association appropriate use recommendations for blood biomarkers in Alzheimer's disease}},
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  title   = {{Plasma phosphorylated tau 217 concentrations, APOE genotype, and timing of cognitive impairment in individuals across diverse racial and ethnic groups: a pooled analysis of prospective cohort studies}},
  journal = {The Lancet. Neurology},
  year    = {2026},
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  title   = {{Defining the Lowest Threshold for Amyloid-PET to Predict Future Cognitive Decline and Amyloid Accumulation}},
  journal = {Neurology},
  year    = {2021},
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@article{delaby2020-32514050,
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  title   = {{Association of Plasma Neurofilament Light With Small Vessel Disease Burden in Nondemented Elderly: A Longitudinal Study}},
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@article{sarto2023-36450604,
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  title   = {{Diagnostic Performance and Clinical Applicability of Blood-Based Biomarkers in a Prospective Memory Clinic Cohort}},
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  year    = {2023},
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@article{vandevrede2025-39928343,
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  title   = {{Detection of Alzheimer Neuropathology in Alzheimer and Non-Alzheimer Clinical Syndromes With Blood-Based Biomarkers}},
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  year    = {2025},
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@article{lehmann2025-40513421,
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  title   = {{Comparative performance of plasma pTau181/Aβ42, pTau217/Aβ42 ratios, and individual measurements in detecting brain amyloidosis}},
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@article{duggan2022-35985823,
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  title   = {{Herpes Viruses in the Baltimore Longitudinal Study of Aging: Associations With Brain Volumes, Cognitive Performance, and Plasma Biomarkers}},
  journal = {Neurology},
  year    = {2022},
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  pmid    = {35985823},
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@article{boerwinkle2021-33931538,
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  title   = {{Temporal Correlation of CSF and Neuroimaging in the Amyloid-Tau-Neurodegeneration Model of Alzheimer Disease}},
  journal = {Neurology},
  year    = {2021},
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@article{grasset2024-38626384,
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  title   = {{Associations Between Blood-Based Biomarkers and Cognitive and Functional Trajectories Among Participants of the MEMENTO Cohort}},
  journal = {Neurology},
  year    = {2024},
  doi     = {10.1212/wnl.0000000000209307},
  pmid    = {38626384},
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@article{zhou2022-36162981,
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  title   = {{Blood β-synuclein is related to amyloid PET positivity in memory clinic patients}},
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  title   = {{Cardiovascular Health and Biomarkers of Neurodegenerative Disease in Older Adults}},
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  year    = {2025},
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@article{dewilde2018-29889941,
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@article{milaaloma2021-34556565,
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  year    = {2021},
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@article{phuah2022-36123127,
  author  = {Phuah, C. L. and Chen, Y. and Strain, J. F. and Yechoor, N. and Laurido-Soto, O. J. and Ances, B. M. and Lee, J. M. and {Alzheimer's Disease Neuroimaging Initiative}},
  title   = {{Association of Data-Driven White Matter Hyperintensity Spatial Signatures With Distinct Cerebral Small Vessel Disease Etiologies}},
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  year    = {2022},
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@article{bermudez2023-37269398,
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@article{lim2022-35099506,
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  title   = {{Association of BDNF Val66Met With Tau Hyperphosphorylation and Cognition in Dominantly Inherited Alzheimer Disease}},
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  year    = {2022},
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  pmid    = {35099506},
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@article{jeong2021-34380754,
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  title   = {{Association of Dipeptidyl Peptidase-4 Inhibitor Use and Amyloid Burden in Patients With Diabetes and AD-Related Cognitive Impairment}},
  journal = {Neurology},
  year    = {2021},
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@article{amariglio2020-32417775,
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  title   = {{Examining Cognitive Decline Across Black and White Participants in the Harvard Aging Brain Study}},
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@article{dumurgier2022-35970577,
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  title   = {{A Pragmatic, Data-Driven Method to Determine Cutoffs for CSF Biomarkers of Alzheimer Disease Based on Validation Against PET Imaging}},
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  year    = {2022},
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@article{kurihara2023-36517236,
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  title   = {{CSF P-Tau181 and Other Biomarkers in Patients With Neuronal Intranuclear Inclusion Disease}},
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  title   = {{Association of Memory Impairment With Concomitant Tau Pathology in Patients With Cerebral Amyloid Angiopathy}},
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@article{angioni2022-35718861,
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  title   = {{Biomarkers of Age-Related Frailty and Frailty Related to Diseases: An Exploratory, Cross-Sectional Analysis from the MAPT Study}},
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@article{zsadanyi2024-39074338,
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  title   = {{Associations of Microbleeds and Their Topography With Imaging and CSF Biomarkers of Alzheimer Pathology in Individuals With Down Syndrome}},
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  year    = {2024},
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  title   = {{Plasma Biomarkers of Brain Injury and Their Association With Brain MRI and Cognition in Type 1 Diabetes}},
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  title   = {{Aerobic exercise does not affect serum neurofilament light in patients with mild Alzheimer's disease}},
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@article{rousset2026-42133312,
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  title   = {{Implication for Clinical Trials From Longitudinal Tau-PET Accumulation Across Biological Alzheimer Disease Stages}},
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@article{halbgebauer2025-41081630,
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@article{tarawneh2026-42098850,
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@article{vanarendonk2024-37535203,
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@article{whitwell2022-35483899,
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@article{gong2025-41250190,
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  year    = {2025},
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@article{quispialaya2025-39715476,
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@article{kuchenbecker2024-37897306,
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@article{couch2023-37561950,
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  title   = {{Beta Amyloid Deposition Is Not Associated With Cognitive Impairment in Parkinson's Disease}},
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  title   = {{Blood-derived mitochondrial DNA copy number is associated with Alzheimer disease, Alzheimer-related biomarkers and serum metabolites}},
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  title   = {{Plasma tau correlates with basal forebrain atrophy rates in people at risk for Alzheimer disease}},
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  pmid    = {31801830},
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@article{dyer2024-39160628,
  author  = {Dyer, A. H. and Dolphin, H. and O'Connor, A. and Morrison, L. and Sedgwick, G. and Young, C. and Killeen, E. and Gallagher, C. and others},
  title   = {{Performance of plasma p-tau217 for the detection of amyloid-β positivity in a memory clinic cohort using an electrochemiluminescence immunoassay}},
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  year    = {2024},
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@article{biechele2022-34016733,
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  title   = {{Glitter in the Darkness? Nonfibrillar β-Amyloid Plaque Components Significantly Impact the β-Amyloid PET Signal in Mouse Models of Alzheimer Disease}},
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@article{whittington2021-33517326,
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@article{wang2018-30569014,
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@article{kern2022-35334608,
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  title   = {{Serum NfL in Alzheimer Dementia: Results of the Prospective Dementia Registry Austria}},
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@article{younes2025-40145384,
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  title   = {{Plasma neurofilament light chain protein is not increased in treatment-resistant schizophrenia and first-degree relatives}},
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  title   = {{Resting-State Functional Connectivity Disruption as a Pathological Biomarker in Autosomal Dominant Alzheimer Disease}},
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  pmid    = {33430685},
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  title   = {{Plasma Alzheimer's biomarkers and brain amyloid in Hispanic and non-Hispanic older adults}},
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  pmid    = {37671801},
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  title   = {{Genetic architecture of plasma Alzheimer disease biomarkers}},
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  year    = {2023},
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  pmid    = {35676734},
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  title   = {{Genome-wide association study identifies two loci influencing plasma neurofilament light levels}},
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  pmid    = {29747637},
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@article{vanderlip2025-40491259,
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  title   = {{Integrating plasma p-tau217 and digital cognitive assessments for early detection in Alzheimer's disease}},
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  year    = {2025},
  doi     = {10.1002/alz.70355},
  pmid    = {40491259},
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@article{aggarwal2024-37233882,
  author  = {Aggarwal, G. and Morley, J. E. and Vellas, B. and Nguyen, A. D. and Butler, A. A. and {MAPT/DSA Group}},
  title   = {{Low circulating adropin concentrations predict increased risk of cognitive decline in community-dwelling older adults}},
  journal = {GeroScience},
  year    = {2024},
  doi     = {10.1007/s11357-023-00824-3},
  pmid    = {37233882},
  url     = {https://doi.org/10.1007/s11357-023-00824-3}
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@article{griswold2025-40133765,
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  title   = {{Generalizability of tau and amyloid plasma biomarkers in Alzheimer's disease cohorts of diverse genetic ancestries}},
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  year    = {2025},
  doi     = {10.1002/alz.14367},
  pmid    = {40133765},
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@article{hall2026-41650358,
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  title   = {{Association of Cortical Free Water With Brain Tau Tangle Load in the Alzheimer Disease Continuum}},
  journal = {Neurology},
  year    = {2026},
  doi     = {10.1212/wnl.0000000000214606},
  pmid    = {41650358},
  url     = {https://doi.org/10.1212/wnl.0000000000214606}
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@article{vivek2026-40492085,
  author  = {Vivek, Sithara and Crimmins, Eileen M. and Kim, Jung Ki and Faul, Jessica D. and Jacobs, David R. and Guan, Weihua and Thyagarajan, Bharat},
  title   = {{Impaired lung function is associated with elevated blood biomarkers of AD/ADRD: unraveling the interplay with risk of dementia}},
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  year    = {2026},
  doi     = {10.1038/s41598-026-48115-z},
  pmid    = {40492085},
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@article{tanner2025-2217c07a,
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  title   = {{Plasma Biomarker Association with Cognition in Uganda}},
  journal = {Alzheimer s \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz70856_106808},
  url     = {https://doi.org/10.1002/alz70856_106808}
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@article{romanoff2025-d1b2aa44,
  author  = {Romanoff, Justin and Gatsonis, Constantine G. and March, Andrew and Apgar, Charles S. and Siegel, Barry Alan and Wilkins, Consuelo Hopkins and Gareen, Ilana F. and Hanna, Lucy and others},
  title   = {{Racial and Ethnic Differences in Amyloid PET Positivity in Individuals With Mild Cognitive Impairment or Dementia}},
  journal = {Carolina Digital Repository (University of North Carolina at Chapel Hill)},
  year    = {2025},
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  url     = {https://doi.org/10.17615/aekj-fb35}
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@article{yim2025-41434464,
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