% alzhub.org library filter % Source: https://alzhub.org/research?category=inflammation&about=treatments % 75 entries, in the order the page lists them. Built from alzhub.org's own records. % 0 entries have no readable author in the source record and carry no author field. @article{cummings2025-39780249, author = {Cummings, J. L. and Atri, A. and Feldman, H. H. and Hansson, O. and Sano, M. and Knop, F. K. and Johannsen, P. and León, T. and others}, title = {{evoke and evoke+: design of two large-scale, double-blind, placebo-controlled, phase 3 studies evaluating efficacy, safety, and tolerability of semaglutide in early-stage symptomatic Alzheimer's disease}}, journal = {Alzheimer's research \& therapy}, year = {2025}, doi = {10.1186/s13195-024-01666-7}, pmid = {39780249}, url = {https://doi.org/10.1186/s13195-024-01666-7} } @article{damesquita2021-33911285, author = {Da Mesquita, S. and Papadopoulos, Z. and Dykstra, T. and Brase, L. and Farias, F. G. and Wall, M. and Jiang, H. and Kodira, C. D. and others}, title = {{Meningeal lymphatics affect microglia responses and anti-Aβ immunotherapy}}, journal = {Nature}, year = {2021}, doi = {10.1038/s41586-021-03489-0}, pmid = {33911285}, url = {https://doi.org/10.1038/s41586-021-03489-0} } @article{suswidiantoro2026-41808871, author = {Suswidiantoro, V. and Tang, K. S. and Rahman, K. and Ariestanti, D. M. and James, R. J. and Yan, C. C. and Kato, M. and Saputri, F. C.}, title = {{Natural compounds as multitarget agents in Alzheimer's diseases: evidence from in vivo and in vitro models}}, journal = {Frontiers in pharmacology}, year = {2026}, doi = {10.3389/fphar.2026.1766470}, pmid = {41808871}, url = {https://doi.org/10.3389/fphar.2026.1766470} } @article{corralizagomez2025-41146261, author = {Corraliza-Gomez, M. and Vargas-Soria, M. and Garcia-Alloza, M.}, title = {{Effect of antidiabetic drugs in Alzheimer´s disease: a systematic review of preclinical and clinical studies}}, journal = {Molecular neurodegeneration}, year = {2025}, doi = {10.1186/s13024-025-00894-1}, pmid = {41146261}, url = {https://doi.org/10.1186/s13024-025-00894-1} } @article{chen2026-41785364, author = {Chen, Yun and Liu, Yizhou A. and Nguyen, Khai M. and Wu, Junjie and Song, Sihui and Lin, Kent and Rodrigues, Patrick Fernandes and Du, Siling and others}, title = {{Targeting amyloid-β pathology by chimeric antigen receptor astrocyte (CAR-A) therapy}}, journal = {Science}, year = {2026}, doi = {10.1126/science.ads3972}, pmid = {41785364}, url = {https://doi.org/10.1126/science.ads3972} } @article{glass1995-7486867, author = {Glass, J. D. and Fedor, H. and Wesselingh, S. L. and McArthur, J. C.}, title = {{Immunocytochemical quantitation of human immunodeficiency virus in the brain: correlations with dementia}}, journal = {Annals of neurology}, year = {1995}, doi = {10.1002/ana.410380510}, pmid = {7486867}, url = {https://doi.org/10.1002/ana.410380510} } @article{chen2023-37452321, author = {Chen, Y. and Yu, Y.}, title = {{Tau and neuroinflammation in Alzheimer's disease: interplay mechanisms and clinical translation}}, journal = {Journal of neuroinflammation}, year = {2023}, doi = {10.1186/s12974-023-02853-3}, pmid = {37452321}, url = {https://doi.org/10.1186/s12974-023-02853-3} } @article{ishmuratova2023-37968954, author = {Ishmuratova, A. N. and Abramov, M. A. and Kuznetsov, K. O. and Ivanyuta, M. V. and Shakirova, Z. F. and Kitapova, A. I. and Usmonov, M. D. and Chernousova, L. M. and others}, title = {{[The role of antidiabetic drugs in the treatment of Alzheimer's disease: systematic review]}}, journal = {Problemy endokrinologii}, year = {2023}, doi = {10.14341/probl13183}, pmid = {37968954}, url = {https://doi.org/10.14341/probl13183} } @article{fulop2020-32458360, author = {Fülöp, T. and Munawara, U. and Larbi, A. and Desroches, M. and Rodrigues, S. and Catanzaro, M. and Guidolin, A. and Khalil, A. and others}, title = {{Targeting Infectious Agents as a Therapeutic Strategy in Alzheimer's Disease}}, journal = {CNS drugs}, year = {2020}, doi = {10.1007/s40263-020-00737-1}, pmid = {32458360}, url = {https://doi.org/10.1007/s40263-020-00737-1} } @article{huang2020-31906949, author = {Huang, L. K. and Chao, S. P. and Hu, C. J.}, title = {{Clinical trials of new drugs for Alzheimer disease}}, journal = {Journal of biomedical science}, year = {2020}, doi = {10.1186/s12929-019-0609-7}, pmid = {31906949}, url = {https://doi.org/10.1186/s12929-019-0609-7} } @article{halliday2000-10696521, author = {Halliday, G. and Robinson, SR. and Shepherd, C. and Kril, J.}, title = {{Alzheimer's disease and inflammation: a review of cellular and therapeutic mechanisms}}, journal = {Clinical and experimental pharmacology \& physiology}, year = {2000}, doi = {10.1046/j.1440-1681.2000.03200.x}, pmid = {10696521}, url = {https://doi.org/10.1046/j.1440-1681.2000.03200.x} } @article{mackenzie1998-9566383, author = {Mackenzie, I. R. and Munoz, D. G.}, title = {{Nonsteroidal anti-inflammatory drug use and Alzheimer-type pathology in aging}}, journal = {Neurology}, year = {1998}, doi = {10.1212/wnl.50.4.986}, pmid = {9566383}, url = {https://doi.org/10.1212/wnl.50.4.986} } @article{edelbach2026-41588887, author = {Edelbach, B. and Huang, L. and Boling, W.}, title = {{Vagus Nerve Stimulation in the Management of Neurodegenerative Diseases: A Systematic Review of Advances in Animal Research and Clinical Applications}}, journal = {Current Alzheimer research}, year = {2026}, doi = {10.2174/0115672050373772251103053036}, pmid = {41588887}, url = {https://doi.org/10.2174/0115672050373772251103053036} } @article{hung2017-28720101, author = {Hung, S. Y. and Fu, W. M.}, title = {{Drug candidates in clinical trials for Alzheimer's disease}}, journal = {Journal of biomedical science}, year = {2017}, doi = {10.1186/s12929-017-0355-7}, pmid = {28720101}, url = {https://doi.org/10.1186/s12929-017-0355-7} } @article{alidoust2023-37311523, author = {Alidoust, L. and Akhoondian, M. and Atefi, A. H. and Keivanlou, M. H. and Hedayati Ch, M. and Jafari, A.}, title = {{Stem cell-conditioned medium is a promising treatment for Alzheimer's disease}}, journal = {Behavioural brain research}, year = {2023}, doi = {10.1016/j.bbr.2023.114543}, pmid = {37311523}, url = {https://doi.org/10.1016/j.bbr.2023.114543} } @article{bell1998-9827765, author = {Bell, J. E. and Brettle, R. P. and Chiswick, A. and Simmonds, P.}, title = {{HIV encephalitis, proviral load and dementia in drug users and homosexuals with AIDS. Effect of neocortical involvement}}, journal = {Brain : a journal of neurology}, year = {1998}, doi = {10.1093/brain/121.11.2043}, pmid = {9827765}, url = {https://doi.org/10.1093/brain/121.11.2043} } @article{noh2025-40640892, author = {Noh, Min‐Young and Kwon, Hyuk Sung and Kwon, Min‐Soo and Nahm, Minyeop and Jin, Hee Kyung and Bae, Jae‐sung and Kim, Seung Hyun}, title = {{Biomarkers and therapeutic strategies targeting microglia in neurodegenerative diseases: current status and future directions}}, journal = {Molecular Neurodegeneration}, year = {2025}, doi = {10.1186/s13024-025-00867-4}, pmid = {40640892}, url = {https://doi.org/10.1186/s13024-025-00867-4} } @article{jantzen2002-11896164, author = {Jantzen, P. T. and Connor, K. E. and DiCarlo, G. and Wenk, G. L. and Wallace, J. L. and Rojiani, A. M. and Coppola, D. and Morgan, D. and others}, title = {{Microglial activation and beta -amyloid deposit reduction caused by a nitric oxide-releasing nonsteroidal anti-inflammatory drug in amyloid precursor protein plus presenilin-1 transgenic mice}}, journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience}, year = {2002}, doi = {10.1523/jneurosci.22-06-02246.2002}, pmid = {11896164}, url = {https://doi.org/10.1523/jneurosci.22-06-02246.2002} } @article{mandler2014-24525765, author = {Mandler, M. and Valera, E. and Rockenstein, E. and Weninger, H. and Patrick, C. and Adame, A. and Santic, R. and Meindl, S. and others}, title = {{Next-generation active immunization approach for synucleinopathies: implications for Parkinson's disease clinical trials}}, journal = {Acta neuropathologica}, year = {2014}, doi = {10.1007/s00401-014-1256-4}, pmid = {24525765}, url = {https://doi.org/10.1007/s00401-014-1256-4} } @article{ballard2020-32939050, author = {Ballard, C. and Aarsland, D. and Cummings, J. and O'Brien, J. and Mills, R. and Molinuevo, J. L. and Fladby, T. and Williams, G. and others}, title = {{Drug repositioning and repurposing for Alzheimer disease}}, journal = {Nature reviews. Neurology}, year = {2020}, doi = {10.1038/s41582-020-0397-4}, pmid = {32939050}, url = {https://doi.org/10.1038/s41582-020-0397-4} } @article{dumont2011-21130159, author = {Dumont, M. and Beal, M. F.}, title = {{Neuroprotective strategies involving ROS in Alzheimer disease}}, journal = {Free radical biology \& medicine}, year = {2011}, doi = {10.1016/j.freeradbiomed.2010.11.026}, pmid = {21130159}, url = {https://doi.org/10.1016/j.freeradbiomed.2010.11.026} } @article{chen2012-23122958, author = {Chen, R. and Zhang, J. and Wu, Y. and Wang, D. and Feng, G. and Tang, Y. P. and Teng, Z. and Chen, C.}, title = {{Monoacylglycerol lipase is a therapeutic target for Alzheimer's disease}}, journal = {Cell reports}, year = {2012}, doi = {10.1016/j.celrep.2012.09.030}, pmid = {23122958}, url = {https://doi.org/10.1016/j.celrep.2012.09.030} } @article{bath2015-25727737, author = {Bath, P. M. and Wardlaw, J. M.}, title = {{Pharmacological treatment and prevention of cerebral small vessel disease: a review of potential interventions}}, journal = {International journal of stroke : official journal of the International Stroke Society}, year = {2015}, doi = {10.1111/ijs.12466}, pmid = {25727737}, url = {https://doi.org/10.1111/ijs.12466} } @article{seo2018-29179999, author = {Seo, E. J. and Fischer, N. and Efferth, T.}, title = {{Phytochemicals as inhibitors of NF-κB for treatment of Alzheimer's disease}}, journal = {Pharmacological research}, year = {2018}, doi = {10.1016/j.phrs.2017.11.030}, pmid = {29179999}, url = {https://doi.org/10.1016/j.phrs.2017.11.030} } @article{aso2014-24634659, author = {Aso, E. and Ferrer, I.}, title = {{Cannabinoids for treatment of Alzheimer's disease: moving toward the clinic}}, journal = {Frontiers in pharmacology}, year = {2014}, doi = {10.3389/fphar.2014.00037}, pmid = {24634659}, url = {https://doi.org/10.3389/fphar.2014.00037} } @article{brandao2025-39813317, author = {Brandão, Wesley Nogueira and Jain, Nimansha and Yin, Zhuoran and Kleemann, Kilian L. and Carpenter, Madison and Bao, Xin and Serrano, Javier Remolina and Tycksen, Eric and others}, title = {{Inhaled xenon modulates microglia and ameliorates disease in mouse models of amyloidosis and tauopathy}}, journal = {Science Translational Medicine}, year = {2025}, doi = {10.1126/scitranslmed.adk3690}, pmid = {39813317}, url = {https://doi.org/10.1126/scitranslmed.adk3690} } @article{gao2012-22503440, author = {Gao, H. M. and Zhou, H. and Hong, J. S.}, title = {{NADPH oxidases: novel therapeutic targets for neurodegenerative diseases}}, journal = {Trends in pharmacological sciences}, year = {2012}, doi = {10.1016/j.tips.2012.03.008}, pmid = {22503440}, url = {https://doi.org/10.1016/j.tips.2012.03.008} } @article{mwale2025-39827337, author = {Mwale, Pharaoh Fellow and Hsieh, Cheng-Ta and Yen, Ting‐Lin and Jan, Jing‐Shiun and Taliyan, Rajeev and Yang, Chih‐Hao and Yang, Wen‐Bin}, title = {{Chitinase-3-like-1: a multifaceted player in neuroinflammation and degenerative pathologies with therapeutic implications}}, journal = {Molecular Neurodegeneration}, year = {2025}, doi = {10.1186/s13024-025-00801-8}, pmid = {39827337}, url = {https://doi.org/10.1186/s13024-025-00801-8} } @article{daponte2025-41097004, author = {Daponte, Ariadne and Koros, Christos and Skarlis, Charalampos and Siozios, Daphne and Rentzos, Michail and Papageorgiou, Sokratis G. and Anagnostouli, Maria C.}, title = {{Neurofilament Biomarkers in Neurology: From Neuroinflammation to Neurodegeneration, Bridging Established and Novel Analytical Advances with Clinical Practice}}, journal = {International Journal of Molecular Sciences}, year = {2025}, doi = {10.3390/ijms26199739}, pmid = {41097004}, url = {https://doi.org/10.3390/ijms26199739} } @article{luo2026-41578396, author = {Luo, Lixin and Qiao, Song}, title = {{Neuroinflammation and blood–brain barrier dysfunction in cerebral small vessel disease: mechanisms, biomarkers, and therapeutic implications}}, journal = {European journal of medical research}, year = {2026}, doi = {10.1186/s40001-026-03840-z}, pmid = {41578396}, url = {https://doi.org/10.1186/s40001-026-03840-z} } @article{liebner2018-29411111, author = {Liebner, S. and Dijkhuizen, R. M. and Reiss, Y. and Plate, K. H. and Agalliu, D. and Constantin, G.}, title = {{Functional morphology of the blood-brain barrier in health and disease}}, journal = {Acta neuropathologica}, year = {2018}, doi = {10.1007/s00401-018-1815-1}, pmid = {29411111}, url = {https://doi.org/10.1007/s00401-018-1815-1} } @article{pisanu2014-25134730, author = {Pisanu, A. and Lecca, D. and Mulas, G. and Wardas, J. and Simbula, G. and Spiga, S. and Carta, A. R.}, title = {{Dynamic changes in pro- and anti-inflammatory cytokines in microglia after PPAR-γ agonist neuroprotective treatment in the MPTPp mouse model of progressive Parkinson's disease}}, journal = {Neurobiology of disease}, year = {2014}, doi = {10.1016/j.nbd.2014.08.011}, pmid = {25134730}, url = {https://doi.org/10.1016/j.nbd.2014.08.011} } @article{dagla2026-41677657, author = {Dagla, Ioanna and Gkikas, Faidon and Gikas, Evagelos and Tsarbopoulos, Anthony}, title = {{Targeting Amyloid Beta Aggregation and Neuroinflammation in Alzheimer’s Disease: Advances and Future Directions}}, journal = {Cells}, year = {2026}, doi = {10.3390/cells15030295}, pmid = {41677657}, url = {https://doi.org/10.3390/cells15030295} } @article{tyagi2026-41510854, author = {Tyagi, S. and Murali, N. and Singh, S. K. and Babtiwale, SR. and Padhi, B. K. and Lakshmi, N. R. A. and Gandhi, A. P.}, title = {{A Systematic Review to Evaluate the Effect of Neflamapimod on Cognitive Function and Progression of Dementia}}, journal = {Neurology India}, year = {2026}, doi = {10.4103/neurol-india.neurol-india-d-25-00227}, pmid = {41510854}, url = {https://doi.org/10.4103/neurol-india.neurol-india-d-25-00227} } @article{tweedie2007-17908040, author = {Tweedie, D. and Sambamurti, K. and Greig, N. H.}, title = {{TNF-alpha inhibition as a treatment strategy for neurodegenerative disorders: new drug candidates and targets}}, journal = {Current Alzheimer research}, year = {2007}, doi = {10.2174/156720507781788873}, pmid = {17908040}, url = {https://doi.org/10.2174/156720507781788873} } @article{zhang2023-37433768, author = {Zhang, W. and Xiao, D. and Mao, Q. and Xia, H.}, title = {{Role of neuroinflammation in neurodegeneration development}}, journal = {Signal transduction and targeted therapy}, year = {2023}, doi = {10.1038/s41392-023-01486-5}, pmid = {37433768}, url = {https://doi.org/10.1038/s41392-023-01486-5} } @article{li2025-40260242, author = {Li, Zhitao and Gong, Chunrong}, title = {{NLRP3 inflammasome in Alzheimer's disease: molecular mechanisms and emerging therapies}}, journal = {Frontiers in immunology}, year = {2025}, doi = {10.3389/fimmu.2025.1583886}, pmid = {40260242}, url = {https://doi.org/10.3389/fimmu.2025.1583886} } @article{serradas2024-39272998, author = {Serradas, Maria L and Ding, Yingying and Martorell, Paula V and Kulińska, Ida and Castro-Gomez, Sergio}, title = {{Therapeutic Targets in Innate Immunity to Tackle Alzheimer's Disease}}, journal = {Cells}, year = {2024}, doi = {10.3390/cells13171426}, pmid = {39272998}, url = {https://doi.org/10.3390/cells13171426} } @article{ylmaz2025-40699631, author = {Yılmaz, Habibe and Bayraktutan, Ulvi}, title = {{Cerebral Small Vessel Disease: Therapeutic Approaches Targeting Neuroinflammation, Oxidative Stress, and Endothelial Dysfunction}}, journal = {Current Issues in Molecular Biology}, year = {2025}, doi = {10.3390/cimb47040232}, pmid = {40699631}, url = {https://doi.org/10.3390/cimb47040232} } @article{yoon2025-40277896, author = {Yoon, Chi‐Su}, title = {{Natural Products in the Treatment of Neuroinflammation at Microglia: Recent Trend and Features}}, journal = {Cells}, year = {2025}, doi = {10.3390/cells14080571}, pmid = {40277896}, url = {https://doi.org/10.3390/cells14080571} } @article{zhai2025-40151913, author = {Zhai, Yanyu and Lu, Kaili and Yuan, Yuan and Zhang, Ziyao and Xue, Lixia and Zhao, Fei and Xu, Xiaofeng and Wang, Hongmei}, title = {{Semaglutide improves cognitive function and neuroinflammation in APP/PS1 transgenic mice by activating AMPK and inhibiting TLR4/NF-κB pathway}}, journal = {Journal of Alzheimer s Disease}, year = {2025}, doi = {10.1177/13872877251329439}, pmid = {40151913}, url = {https://doi.org/10.1177/13872877251329439} } @article{akif2025-40462117, author = {Akif, Adnan and Nguyen, T.T. and Liu, Langni and Xu, Xiaotian and Kulkarni, Amol A. and Jiang, Jianxiong and Zhang, Yang and Hao, Jiukuan}, title = {{Targeting NLRP3 signaling with a novel sulfonylurea compound for the treatment of vascular cognitive impairment and dementia}}, journal = {Fluids and Barriers of the CNS}, year = {2025}, doi = {10.1186/s12987-025-00665-6}, pmid = {40462117}, url = {https://doi.org/10.1186/s12987-025-00665-6} } @article{zhang2019-30936558, author = {Zhang, P. and Kishimoto, Y. and Grammatikakis, I. and Gottimukkala, K. and Cutler, R. G. and Zhang, S. and Abdelmohsen, K. and Bohr, V. A. and others}, title = {{Senolytic therapy alleviates Aβ-associated oligodendrocyte progenitor cell senescence and cognitive deficits in an Alzheimer's disease model}}, journal = {Nature neuroscience}, year = {2019}, doi = {10.1038/s41593-019-0372-9}, pmid = {30936558}, url = {https://doi.org/10.1038/s41593-019-0372-9} } @article{kim2021-34638977, author = {Kim, Jieun and Lee, Hyun-Ju and Park, Seon Kyeong and Park, Jin-Hee and Jeong, Ha-Ram and Lee, Soojung and Lee, Heeyong and Seol, Eunyoung and others}, title = {{Donepezil Regulates LPS and Aβ-Stimulated Neuroinflammation through MAPK/NLRP3 Inflammasome/STAT3 Signaling}}, journal = {International journal of molecular sciences}, year = {2021}, doi = {10.3390/ijms221910637}, pmid = {34638977}, url = {https://doi.org/10.3390/ijms221910637} } @article{barczuk2022-36012243, author = {Barczuk, Julia and Siwecka, Natalia and Lusa, Weronika and Rozpędek-Kamińska, Wioletta and Kucharska, Ewa and Majsterek, Ireneusz}, title = {{Targeting NLRP3-Mediated Neuroinflammation in Alzheimer's Disease Treatment}}, journal = {International journal of molecular sciences}, year = {2022}, doi = {10.3390/ijms23168979}, pmid = {36012243}, url = {https://doi.org/10.3390/ijms23168979} } @article{rather2021-34381308, author = {Rather, Mashoque Ahmad and Khan, Andleeb and Alshahrani, Saeed and Rashid, Hina and Qadri, Marwa and Rashid, Summya and Alsaffar, Rana M and Kamal, Mohammad Amjad and others}, title = {{Inflammation and Alzheimer's Disease: Mechanisms and Therapeutic Implications by Natural Products}}, journal = {Mediators of inflammation}, year = {2021}, doi = {10.1155/2021/9982954}, pmid = {34381308}, url = {https://doi.org/10.1155/2021/9982954} } @article{susjanleite2022-35979366, author = {Sušjan-Leite, Petra and Ramuta, Taja Železnik and Boršić, Elvira and Orehek, Sara and Hafner-Bratkovič, Iva}, title = {{Supramolecular organizing centers at the interface of inflammation and neurodegeneration}}, journal = {Frontiers in immunology}, year = {2022}, doi = {10.3389/fimmu.2022.940969}, pmid = {35979366}, url = {https://doi.org/10.3389/fimmu.2022.940969} } @article{golzarisorkheh2021-34569958, author = {Golzari-Sorkheh, Mahdieh and Brown, Carla E and Weaver, Donald F and Reed, Mark A}, title = {{The NLRP3 Inflammasome in the Pathogenesis and Treatment of Alzheimer's Disease}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2021}, doi = {10.3233/jad-210660}, pmid = {34569958}, url = {https://doi.org/10.3233/jad-210660} } @article{jung2022-35474599, author = {Jung, Eun Sun and Suh, Kyujin and Han, Jihui and Kim, Heyyoung and Kang, Hyung-Sik and Choi, Won-Seok and Mook-Jung, Inhee}, title = {{Amyloid-β activates NLRP3 inflammasomes by affecting microglial immunometabolism through the Syk-AMPK pathway}}, journal = {Aging cell}, year = {2022}, doi = {10.1111/acel.13623}, pmid = {35474599}, url = {https://doi.org/10.1111/acel.13623} } @article{dhandapani2002-12390866, author = {Dhandapani, K. M. and Brann, D. W.}, title = {{Protective effects of estrogen and selective estrogen receptor modulators in the brain}}, journal = {Biology of reproduction}, year = {2002}, doi = {10.1095/biolreprod.102.003848}, pmid = {12390866}, url = {https://doi.org/10.1095/biolreprod.102.003848} } @article{angst2025-40395993, author = {Angst, Gabrielle and Jia, Nuo and Esqueda, Luis Tron and Fan, Yanbo and Cai, Qian and Wang, Chenran}, title = {{Autophagy in alzheimer disease pathogenesis and its therapeutic values}}, journal = {Autophagy Reports}, year = {2025}, doi = {10.1080/27694127.2025.2471677}, pmid = {40395993}, url = {https://doi.org/10.1080/27694127.2025.2471677} } @article{kakkar2025-40938771, author = {Kakkar, A. K. and Singh, Harpreet and Singh, Bhuvnesh Kumar and Kumar, Arvind and Mishra, Arun Kumar and Chopra, Hitesh}, title = {{Neuroinflammation and Alzheimer's disease: Unravelling the molecular mechanisms}}, journal = {Journal of Alzheimer s Disease}, year = {2025}, doi = {10.1177/13872877251374353}, pmid = {40938771}, url = {https://doi.org/10.1177/13872877251374353} } @article{zhao2025-40145977, author = {Zhao, Wenhui and Liu, Zhongxuan and Wu, Jiannan and Liu, Anran and Yan, Junqiang}, title = {{Potential targets of microglia in the treatment of neurodegenerative diseases: Mechanism and therapeutic implications}}, journal = {Neural Regeneration Research}, year = {2025}, doi = {10.4103/nrr.nrr-d-24-01343}, pmid = {40145977}, url = {https://doi.org/10.4103/nrr.nrr-d-24-01343} } @article{untu2025-40529210, author = {Untu, Ilinca and Davidson, Michael and Stanciu, Gabriela Dumitriţa and Rabinowitz, Jonathan and Dobrin, Romeo and Vieru, Diana Sabina and Tamba, Bogdan-Ionel}, title = {{Neurobiological and therapeutic landmarks of depression associated with Alzheimer’s disease dementia}}, journal = {Frontiers in Aging Neuroscience}, year = {2025}, doi = {10.3389/fnagi.2025.1584607}, pmid = {40529210}, url = {https://doi.org/10.3389/fnagi.2025.1584607} } @article{abdellah2025-40325262, author = {Abdel-Lah, Ebtsam S and Sherkawy, Hoda S. and Mohamed, Wafaa H. and Fawy, Mariam A. and Hasan, Asmaa A. and Muhammed, Asmaa A. and Taha, Amira F. and Tony, Abeer A. and others}, title = {{Empagliflozin and memantine combination ameliorates cognitive impairment in scopolamine + heavy metal mixture-induced Alzheimer’s disease in rats: role of AMPK/mTOR, BDNF, BACE-1, neuroinflammation, and oxidative stress}}, journal = {Inflammopharmacology}, year = {2025}, doi = {10.1007/s10787-025-01755-5}, pmid = {40325262}, url = {https://doi.org/10.1007/s10787-025-01755-5} } @article{beretti2025-41595595, author = {Beretti, Francesca and Malenchini, Marta and Gatti, Martina and Maraldi, Tullia}, title = {{Oxidative Stress as a Central Mechanistic Bridge Between Alzheimer’s and Vascular Pathologies in Mixed Dementia: Emerging Evidence and Therapeutic Perspectives}}, journal = {Biomedicines}, year = {2025}, doi = {10.3390/biomedicines14010059}, pmid = {41595595}, url = {https://doi.org/10.3390/biomedicines14010059} } @article{guan2020-32792920, author = {Guan, Yadi and Han, Fang}, title = {{Key Mechanisms and Potential Targets of the NLRP3 Inflammasome in Neurodegenerative Diseases}}, journal = {Frontiers in integrative neuroscience}, year = {2020}, doi = {10.3389/fnint.2020.00037}, pmid = {32792920}, url = {https://doi.org/10.3389/fnint.2020.00037} } @article{arrant2018-29378861, author = {Arrant, A. E. and Onyilo, V. C. and Unger, D. E. and Roberson, E. D.}, title = {{Progranulin Gene Therapy Improves Lysosomal Dysfunction and Microglial Pathology Associated with Frontotemporal Dementia and Neuronal Ceroid Lipofuscinosis}}, journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience}, year = {2018}, doi = {10.1523/jneurosci.3081-17.2018}, pmid = {29378861}, url = {https://doi.org/10.1523/jneurosci.3081-17.2018} } @article{nuovo2025-39931956, author = {Nuovo, Gerard J. and Rice, Madison and Zanesi, Nicola A. O. and Sawant, Dwitiya B. and Crilly, Candice J. and Tili, Esmerina}, title = {{The Prevention of Fatal Tauopathy in a Mouse Model of Alzheimer Disease by Blocking BCL2}}, journal = {Applied immunohistochemistry \& molecular morphology}, year = {2025}, doi = {10.1097/pai.0000000000001251}, pmid = {39931956}, url = {https://doi.org/10.1097/pai.0000000000001251} } @article{dunacka2025-40283962, author = {Dunacka, Joanna and Grembecka, Beata and Majkutewicz, Irena and Wrona, Danuta}, title = {{Central Insulin-like Growth Factor-1 Treatment Enhances Working and Reference Memory by Reducing Neuroinflammation and Amyloid Beta Deposition in a Rat Model of Sporadic Alzheimer’s Disease}}, journal = {Pharmaceuticals}, year = {2025}, doi = {10.3390/ph18040527}, pmid = {40283962}, url = {https://doi.org/10.3390/ph18040527} } @article{yang2025-40741047, author = {Yang, Yanrong and Chen, Hua and Liu, Qibing and Niu, Yang and Mao, Chunyang and Wang, R.Y.}, title = {{Elucidating molecular pathogenesis and developing targeted therapeutic interventions for cerebrovascular endothelial cell-mediated vascular dementia}}, journal = {Frontiers in Aging Neuroscience}, year = {2025}, doi = {10.3389/fnagi.2025.1623050}, pmid = {40741047}, url = {https://doi.org/10.3389/fnagi.2025.1623050} } @article{bu2025-40337511, author = {Bu, Yifan and Li, Songzhe and Ye, Ting and Wang, Yuqing and Song, Mingrong and Chen, Jing}, title = {{Volatile oil of Acori tatarinowii rhizoma: potential candidate drugs for mitigating dementia}}, journal = {Frontiers in Pharmacology}, year = {2025}, doi = {10.3389/fphar.2025.1552801}, pmid = {40337511}, url = {https://doi.org/10.3389/fphar.2025.1552801} } @article{latta2015-25286385, author = {Latta, C. H. and Brothers, H. M. and Wilcock, D. M.}, title = {{Neuroinflammation in Alzheimer's disease; A source of heterogeneity and target for personalized therapy}}, journal = {Neuroscience}, year = {2015}, doi = {10.1016/j.neuroscience.2014.09.061}, pmid = {25286385}, url = {https://doi.org/10.1016/j.neuroscience.2014.09.061} } @article{takata2010-20947502, author = {Takata, K. and Kitamura, Y. and Saeki, M. and Terada, M. and Kagitani, S. and Kitamura, R. and Fujikawa, Y. and Maelicke, A. and others}, title = {{Galantamine-induced amyloid-beta clearance mediated via stimulation of microglial nicotinic acetylcholine receptors}}, journal = {The Journal of biological chemistry}, year = {2010}, doi = {10.1074/jbc.m110.142356}, pmid = {20947502}, url = {https://doi.org/10.1074/jbc.m110.142356} } @article{vane1998-9597150, author = {Vane, JR. and Bakhle, Y. S. and Botting, R. M.}, title = {{Cyclooxygenases 1 and 2}}, journal = {Annual review of pharmacology and toxicology}, year = {1998}, doi = {10.1146/annurev.pharmtox.38.1.97}, pmid = {9597150}, url = {https://doi.org/10.1146/annurev.pharmtox.38.1.97} } @article{saraiva2016-27208862, author = {Saraiva, C. and Praça, C. and Ferreira, R. and Santos, T. and Ferreira, L. and Bernardino, L.}, title = {{Nanoparticle-mediated brain drug delivery: Overcoming blood-brain barrier to treat neurodegenerative diseases}}, journal = {Journal of controlled release : official journal of the Controlled Release Society}, year = {2016}, doi = {10.1016/j.jconrel.2016.05.044}, pmid = {27208862}, url = {https://doi.org/10.1016/j.jconrel.2016.05.044} } @article{halliwell2001-11599635, author = {Halliwell, B.}, title = {{Role of free radicals in the neurodegenerative diseases: therapeutic implications for antioxidant treatment}}, journal = {Drugs \& aging}, year = {2001}, doi = {10.2165/00002512-200118090-00004}, pmid = {11599635}, url = {https://doi.org/10.2165/00002512-200118090-00004} } @article{lucas2006-16402109, author = {Lucas, S. M. and Rothwell, N. J. and Gibson, R. M.}, title = {{The role of inflammation in CNS injury and disease}}, journal = {British journal of pharmacology}, year = {2006}, doi = {10.1038/sj.bjp.0706400}, pmid = {16402109}, url = {https://doi.org/10.1038/sj.bjp.0706400} } @article{liu2003-12490568, author = {Liu, B. and Hong, J. S.}, title = {{Role of microglia in inflammation-mediated neurodegenerative diseases: mechanisms and strategies for therapeutic intervention}}, journal = {The Journal of pharmacology and experimental therapeutics}, year = {2003}, doi = {10.1124/jpet.102.035048}, pmid = {12490568}, url = {https://doi.org/10.1124/jpet.102.035048} } @article{tansey2010-19913097, author = {Tansey, M. G. and Goldberg, M. S.}, title = {{Neuroinflammation in Parkinson's disease: its role in neuronal death and implications for therapeutic intervention}}, journal = {Neurobiology of disease}, year = {2010}, doi = {10.1016/j.nbd.2009.11.004}, pmid = {19913097}, url = {https://doi.org/10.1016/j.nbd.2009.11.004} } @article{jubair2026-41696896, author = {Jubair, Hassan}, title = {{Glial cells in dementia: From cellular dysfunction to therapeutic frontiers}}, journal = {Cell Transplantation}, year = {2026}, doi = {10.1177/09636897251414216}, pmid = {41696896}, url = {https://doi.org/10.1177/09636897251414216} } @article{meng2026-42108759, author = {Meng, Qingfu and Li, Jianning and Xu, Gaungxu and Zhang, Wei and Cao, Rong and Cai, Keshu}, title = {{Ginsenoside Rh2 Alleviates Alzheimer Disease Models via Effects on Ferroptosis‐Related Neuroinflammation}}, journal = {Journal of Biochemical and Molecular Toxicology}, year = {2026}, doi = {10.1002/jbt.70860}, pmid = {42108759}, url = {https://doi.org/10.1002/jbt.70860} } @article{nietobenito2025-40204134, author = {Nieto-Benito, L. M. and Suárez-Fernández, R.}, title = {{Unraveling the Link Between Bullous Pemphigoid and Neurological Disease: A Single-center Study of 257 Patients}}, journal = {Actas dermo-sifiliograficas}, year = {2025}, doi = {10.1016/j.ad.2024.10.071}, pmid = {40204134}, url = {https://doi.org/10.1016/j.ad.2024.10.071} } @article{singh2025-1ee39399, author = {Singh, Asem Surindro and Naqvi, Afsar Raza and Chanu, Machathoibi Takhellambam}, title = {{Neuroinflammation and progress in clinical trials for the treatment of Alzheimer’s disease and related dementias: An update}}, journal = {Innovative Medicines \& Omics}, year = {2025}, doi = {10.36922/imo025050007}, url = {https://doi.org/10.36922/imo025050007} } @article{ty2025-f3f31562, author = {Ty, Cheyenne and Penland, Abigail and Gerving, John and Mendoza-Ceja, Martin and Pratt, Megan and Larripa, Kamila}, title = {{Investigating Potential Alzheimer's Disease Therapies through an Agent-Based Model of Impaired Microglia MetabolismModeling Impaired Microglia Metabolism}}, journal = {Spora A Journal of Biomathematics}, year = {2025}, doi = {10.61403/2473-5493.1111}, url = {https://doi.org/10.61403/2473-5493.1111} }