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% Source: https://alzhub.org/research?about=treatments
% 500 entries, in the order the page lists them. Built from alzhub.org's own records.
% 0 entries have no readable author in the source record and carry no author field.

@article{pascuallucas2025-41058018,
  author  = {Pascual-Lucas, M. and Lacosta, A. M. and Montañés, M. and Canudas, J. and Loscos, J. and Monleón, I. and Allué, J. A. and Sarasa, L. and others},
  title   = {{Safety, tolerability, immunogenicity, and efficacy of ABvac40 active immunotherapy against Aβ40 in patients with mild cognitive impairment or very mild Alzheimer's disease: A randomized, double-blind, placebo-controlled phase 2 study}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2025},
  doi     = {10.1002/alz.70776},
  pmid    = {41058018},
  url     = {https://doi.org/10.1002/alz.70776}
}

@article{nong2025-40813122,
  author  = {Nong, Kailei and Jeppesen, Britta Tendal and Shi, Qingyang and Agoritsas, Thomas and Guyatt, Gordon H and White, Heath and Gao, Yiyuan and Agarwal, Arnav and others},
  title   = {{Medications for adults with type 2 diabetes: a living systematic review and network meta-analysis}},
  journal = {BMJ (Clinical research ed.)},
  year    = {2025},
  doi     = {10.1136/bmj-2024-083039},
  pmid    = {40813122},
  url     = {https://doi.org/10.1136/bmj-2024-083039}
}

@article{salloway2025-40390253,
  author  = {Salloway, S. and Pain, A. and Lee, E. and Papka, M. and Ferguson, M. B. and Wang, H. and Hu, H. and Lu, M. and others},
  title   = {{TRAILBLAZER-ALZ 4: A phase 3 trial comparing donanemab with aducanumab on amyloid plaque clearance in early, symptomatic Alzheimer's disease}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2025},
  doi     = {10.1002/alz.70293},
  pmid    = {40390253},
  url     = {https://doi.org/10.1002/alz.70293}
}

@article{shulman2023-38012285,
  author  = {Shulman, M. and Kong, J. and O'Gorman, J. and Ratti, E. and Rajagovindan, R. and Viollet, L. and Huang, E. and Sharma, S. and others},
  title   = {{TANGO: a placebo-controlled randomized phase 2 study of efficacy and safety of the anti-tau monoclonal antibody gosuranemab in early Alzheimer's disease}},
  journal = {Nature aging},
  year    = {2023},
  doi     = {10.1038/s43587-023-00523-w},
  pmid    = {38012285},
  url     = {https://doi.org/10.1038/s43587-023-00523-w}
}

@article{tseng2025-40189519,
  author  = {Tseng, Ping-Tao and Zeng, Bing-Yan and Hsu, Chih-Wei and Hung, Chao-Ming and Carvalho, Andre F and Stubbs, Brendon and Chen, Yen-Wen and Chen, Tien-Yu and others},
  title   = {{The pharmacodynamics-based prophylactic benefits of GLP-1 receptor agonists and SGLT2 inhibitors on neurodegenerative diseases: evidence from a network meta-analysis}},
  journal = {BMC medicine},
  year    = {2025},
  doi     = {10.1186/s12916-025-04018-w},
  pmid    = {40189519},
  url     = {https://doi.org/10.1186/s12916-025-04018-w}
}

@article{yunusa2019-30901041,
  author  = {Yunusa, I. and Alsumali, A. and Garba, A. E. and Regestein, Q. R. and Eguale, T.},
  title   = {{Assessment of Reported Comparative Effectiveness and Safety of Atypical Antipsychotics in the Treatment of Behavioral and Psychological Symptoms of Dementia: A Network Meta-analysis}},
  journal = {JAMA network open},
  year    = {2019},
  doi     = {10.1001/jamanetworkopen.2019.0828},
  pmid    = {30901041},
  url     = {https://doi.org/10.1001/jamanetworkopen.2019.0828}
}

@article{dantas2024-37978096,
  author  = {Dantas, J. M. and Mutarelli, A. and Navalha, D. D. P. and Dagostin, C. S. and Romeiro, P. H. C. L. and Felix, N. and Nogueira, A. and Batista, S. and others},
  title   = {{Efficacy of anti-amyloid-ß monoclonal antibody therapy in early Alzheimer's disease: a systematic review and meta-analysis}},
  journal = {Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology},
  year    = {2024},
  doi     = {10.1007/s10072-023-07194-w},
  pmid    = {37978096},
  url     = {https://doi.org/10.1007/s10072-023-07194-w}
}

@article{salloway2014-24450891,
  author  = {Salloway, S. and Sperling, R. and Fox, N. C. and Blennow, K. and Klunk, W. and Raskind, M. and Sabbagh, M. and Honig, L. S. and others},
  title   = {{Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease}},
  journal = {The New England journal of medicine},
  year    = {2014},
  doi     = {10.1056/nejmoa1304839},
  pmid    = {24450891},
  url     = {https://doi.org/10.1056/nejmoa1304839}
}

@article{macfarlane2025-39800452,
  author  = {Macfarlane, S. and Grimmer, T. and Teo, K. and O'Brien, T. J. and Woodward, M. and Grunfeld, J. and Mander, A. and Brodtmann, A. and others},
  title   = {{Blarcamesine for the treatment of Early Alzheimer's Disease: Results from the ANAVEX2-73-AD-004 Phase IIB/III trial}},
  journal = {The journal of prevention of Alzheimer's disease},
  year    = {2025},
  doi     = {10.1016/j.tjpad.2024.100016},
  pmid    = {39800452},
  url     = {https://doi.org/10.1016/j.tjpad.2024.100016}
}

@article{avgerinos2021-33831607,
  author  = {Avgerinos, K. I. and Ferrucci, L. and Kapogiannis, D.},
  title   = {{Effects of monoclonal antibodies against amyloid-β on clinical and biomarker outcomes and adverse event risks: A systematic review and meta-analysis of phase III RCTs in Alzheimer's disease}},
  journal = {Ageing research reviews},
  year    = {2021},
  doi     = {10.1016/j.arr.2021.101339},
  pmid    = {33831607},
  url     = {https://doi.org/10.1016/j.arr.2021.101339}
}

@article{qiao2024-38429615,
  author  = {Qiao, Y. and Gu, J. and Yu, M. and Chi, Y. and Ma, Y.},
  title   = {{Comparative Efficacy and Safety of Monoclonal Antibodies for Cognitive Decline in Patients with Alzheimer's Disease: A Systematic Review and Network Meta-Analysis}},
  journal = {CNS drugs},
  year    = {2024},
  doi     = {10.1007/s40263-024-01067-2},
  pmid    = {38429615},
  url     = {https://doi.org/10.1007/s40263-024-01067-2}
}

@article{toda2024-39350371,
  author  = {Toda, Y. and Iwatsubo, T. and Nakamura, Y. and Matsuda, N. and Miyata, M. and Jin, M. and Chen, T. and Kuribayashi, K. and others},
  title   = {{Japanese Subgroup Analyses from EMERGE and ENGAGE, Phase 3 Clinical Trials of Aducanumab in Patients with Early Alzheimer's Disease}},
  journal = {The journal of prevention of Alzheimer's disease},
  year    = {2024},
  doi     = {10.14283/jpad.2024.106},
  pmid    = {39350371},
  url     = {https://doi.org/10.14283/jpad.2024.106}
}

@article{kutzsche2025-40324978,
  author  = {Kutzsche, J. and Cosma, N. C. and Kauselmann, G. and Fenski, F. and Bieniek, C. and Bujnicki, T. and Pils, M. and Bannach, O. and others},
  title   = {{Oral PRI-002 treatment in patients with MCI or mild AD: a randomized, double-blind phase 1b trial}},
  journal = {Nature communications},
  year    = {2025},
  doi     = {10.1038/s41467-025-59295-z},
  pmid    = {40324978},
  url     = {https://doi.org/10.1038/s41467-025-59295-z}
}

@article{abdelhaleem2026-40435316,
  author  = {Abdel-Haleem, Alyaa M and Casavant, Ellen and Toth, Balazs and Teng, Edmond and Monteiro, Cecilia and Pandya, Nikhil J and Glock, Caspar and Hoogenraad, Casper C and others},
  title   = {{CSF proteomics of semorinemab Alzheimer's disease trials identifies cell-type specific signatures}},
  journal = {Brain : a journal of neurology},
  year    = {2026},
  doi     = {10.1093/brain/awaf200},
  pmid    = {40435316},
  url     = {https://doi.org/10.1093/brain/awaf200}
}

@article{mehta2017-28832937,
  author  = {Mehta, Nishila and Rodrigues, Craig and Lamba, Manpreet and Wu, Wei and Bronskill, Susan E and Herrmann, Nathan and Gill, Sudeep S and Chan, An-Wen and others},
  title   = {{Systematic Review of Sex-Specific Reporting of Data: Cholinesterase Inhibitor Example}},
  journal = {Journal of the American Geriatrics Society},
  year    = {2017},
  doi     = {10.1111/jgs.15020},
  pmid    = {28832937},
  url     = {https://doi.org/10.1111/jgs.15020}
}

@article{zimmer2025-40063015,
  author  = {Zimmer, J. A. and Ardayfio, P. and Wang, H. and Khanna, R. and Evans, C. D. and Lu, M. and Sparks, J. and Andersen, S. and Lauzon, S. and Nery, E. S. M. and others},
  title   = {{Amyloid-Related Imaging Abnormalities With Donanemab in Early Symptomatic Alzheimer Disease: Secondary Analysis of the TRAILBLAZER-ALZ and ALZ 2 Randomized Clinical Trials}},
  journal = {JAMA Neurology},
  year    = {2025},
  doi     = {10.1001/jamaneurol.2025.0065},
  pmid    = {40063015},
  url     = {https://doi.org/10.1001/jamaneurol.2025.0065}
}

@article{salloway2022-34807243,
  author  = {Salloway, S. and Chalkias, S. and Barkhof, F. and Burkett, P. and Barakos, J. and Purcell, D. and Suhy, J. and Forrestal, F. and others},
  title   = {{Amyloid-Related Imaging Abnormalities in 2 Phase 3 Studies Evaluating Aducanumab in Patients With Early Alzheimer Disease}},
  journal = {JAMA neurology},
  year    = {2022},
  doi     = {10.1001/jamaneurol.2021.4161},
  pmid    = {34807243},
  url     = {https://doi.org/10.1001/jamaneurol.2021.4161}
}

@article{birks2006-16437430,
  author  = {Birks, J. and Harvey, R. J.},
  title   = {{Donepezil for dementia due to Alzheimer's disease}},
  journal = {The Cochrane database of systematic reviews},
  year    = {2006},
  doi     = {10.1002/14651858.cd001190.pub2},
  pmid    = {16437430},
  url     = {https://doi.org/10.1002/14651858.cd001190.pub2}
}

@article{liang2018-29768349,
  author  = {Liang, J. H. and Xu, Y. and Lin, L. and Jia, R. X. and Zhang, H. B. and Hang, L.},
  title   = {{Comparison of multiple interventions for older adults with Alzheimer disease or mild cognitive impairment: A PRISMA-compliant network meta-analysis}},
  journal = {Medicine},
  year    = {2018},
  doi     = {10.1097/md.0000000000010744},
  pmid    = {29768349},
  url     = {https://doi.org/10.1097/md.0000000000010744}
}

@article{rashad2022-36611492,
  author  = {Rashad, A. and Rasool, A. and Shaheryar, M. and Sarfraz, A. and Sarfraz, Z. and Robles-Velasco, K. and Cherrez-Ojeda, I.},
  title   = {{Donanemab for Alzheimer's Disease: A Systematic Review of Clinical Trials}},
  journal = {Healthcare (Basel, Switzerland)},
  year    = {2022},
  doi     = {10.3390/healthcare11010032},
  pmid    = {36611492},
  url     = {https://doi.org/10.3390/healthcare11010032}
}

@article{chen2024-38567735,
  author  = {Chen, T. and O'Gorman, J. and Castrillo-Viguera, C. and Rajagovindan, R. and Curiale, G. G. and Tian, Y. and Patel, D. and von Rosenstiel, P. and others},
  title   = {{Results from the long-term extension of PRIME: A randomized Phase 1b trial of aducanumab}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2024},
  doi     = {10.1002/alz.13755},
  pmid    = {38567735},
  url     = {https://doi.org/10.1002/alz.13755}
}

@article{hsu2025-40316479,
  author  = {Hsu, C. W. and Hsu, T. W. and Kao, Y. C. and Lin, Y. H. and Thompson, T. and Carvalho, A. F. and Stubbs, B. and Tseng, P. T. and others},
  title   = {{The efficacy and safety of anti-amyloid monoclonal antibody versus acetylcholinesterase inhibitor with an in-depth analysis across genotypes and disease stages: a systematic review and meta-analysis}},
  journal = {The journal of prevention of Alzheimer's disease},
  year    = {2025},
  doi     = {10.1016/j.tjpad.2025.100195},
  pmid    = {40316479},
  url     = {https://doi.org/10.1016/j.tjpad.2025.100195}
}

@article{biessels2019-31399442,
  author  = {Biessels, G. J. and Verhagen, C. and Janssen, J. and van den Berg, E. and Zinman, B. and Rosenstock, J. and George, J. T. and Passera, A. and others},
  title   = {{Effect of Linagliptin on Cognitive Performance in Patients With Type 2 Diabetes and Cardiorenal Comorbidities: The CARMELINA Randomized Trial}},
  journal = {Diabetes care},
  year    = {2019},
  doi     = {10.2337/dc19-0783},
  pmid    = {31399442},
  url     = {https://doi.org/10.2337/dc19-0783}
}

@article{liang2024-38746639,
  author  = {Liang, Y. and Doré, V. and Rowe, C. C. and Krishnadas, N.},
  title   = {{Clinical Evidence for GLP-1 Receptor Agonists in Alzheimer's Disease: A Systematic Review}},
  journal = {Journal of Alzheimer's disease reports},
  year    = {2024},
  doi     = {10.3233/adr-230181},
  pmid    = {38746639},
  url     = {https://doi.org/10.3233/adr-230181}
}

@article{matsunaga2015-25860130,
  author  = {Matsunaga, S. and Kishi, T. and Iwata, N.},
  title   = {{Memantine monotherapy for Alzheimer's disease: a systematic review and meta-analysis}},
  journal = {PloS one},
  year    = {2015},
  doi     = {10.1371/journal.pone.0123289},
  pmid    = {25860130},
  url     = {https://doi.org/10.1371/journal.pone.0123289}
}

@article{bateman2025-40120616,
  author  = {Bateman, Randall J and Li, Yan and McDade, Eric M and Llibre-Guerra, Jorge J and Clifford, David B and Atri, Alireza and Mills, Susan L and Santacruz, Anna M and others},
  title   = {{Safety and efficacy of long-term gantenerumab treatment in dominantly inherited Alzheimer's disease: an open-label extension of the phase 2/3 multicentre, randomised, double-blind, placebo-controlled platform DIAN-TU trial}},
  journal = {The Lancet. Neurology},
  year    = {2025},
  doi     = {10.1016/s1474-4422(25)00024-9},
  pmid    = {40120616},
  url     = {https://doi.org/10.1016/s1474-4422(25)00024-9}
}

@article{perry2026-41689888,
  author  = {Perry, Richard and Kipps, Christopher and Martín, Maria Eugenia Soto and Bozzali, Marco and Logroscino, Giancarlo and Trafford, Sarah and Dhadda, Shobha and Kanekiyo, Michio and others},
  title   = {{Lecanemab for treatment of individuals with early Alzheimer's Disease (AD) who are apolipoprotein E ε4 (ApoE ε4) non-carriers or heterozygotes}},
  journal = {The journal of prevention of Alzheimer's disease},
  year    = {2026},
  doi     = {10.1016/j.tjpad.2026.100507},
  pmid    = {41689888},
  url     = {https://doi.org/10.1016/j.tjpad.2026.100507}
}

@article{buddhaeberlein2022-35542991,
  author  = {Budd Haeberlein, S. and Aisen, P. S. and Barkhof, F. and Chalkias, S. and Chen, T. and Cohen, S. and Dent, G. and Hansson, O. and others},
  title   = {{Two Randomized Phase 3 Studies of Aducanumab in Early Alzheimer's Disease}},
  journal = {The journal of prevention of Alzheimer's disease},
  year    = {2022},
  doi     = {10.14283/jpad.2022.30},
  pmid    = {35542991},
  url     = {https://doi.org/10.14283/jpad.2022.30}
}

@article{pontecorvo2022-36251300,
  author  = {Pontecorvo, M. J. and Lu, M. and Burnham, S. C. and Schade, A. E. and Dage, J. L. and Shcherbinin, S. and Collins, E. C. and Sims, JR. and others},
  title   = {{Association of Donanemab Treatment With Exploratory Plasma Biomarkers in Early Symptomatic Alzheimer Disease: A Secondary Analysis of the TRAILBLAZER-ALZ Randomized Clinical Trial}},
  journal = {JAMA neurology},
  year    = {2022},
  doi     = {10.1001/jamaneurol.2022.3392},
  pmid    = {36251300},
  url     = {https://doi.org/10.1001/jamaneurol.2022.3392}
}

@article{schneider2005-16234500,
  author  = {Schneider, L. S. and Dagerman, K. S. and Insel, P.},
  title   = {{Risk of death with atypical antipsychotic drug treatment for dementia: meta-analysis of randomized placebo-controlled trials}},
  journal = {JAMA},
  year    = {2005},
  doi     = {10.1001/jama.294.15.1934},
  pmid    = {16234500},
  url     = {https://doi.org/10.1001/jama.294.15.1934}
}

@article{winblad2008-18322263,
  author  = {Winblad, B. and Gauthier, S. and Scinto, L. and Feldman, H. and Wilcock, G. K. and Truyen, L. and Mayorga, A. J. and Wang, D. and others},
  title   = {{Safety and efficacy of galantamine in subjects with mild cognitive impairment}},
  journal = {Neurology},
  year    = {2008},
  doi     = {10.1212/01.wnl.0000303815.69777.26},
  pmid    = {18322263},
  url     = {https://doi.org/10.1212/01.wnl.0000303815.69777.26}
}

@article{terao2024-38253184,
  author  = {Terao, Itsuki and Kodama, Wakako},
  title   = {{Comparative efficacy, tolerability and acceptability of donanemab, lecanemab, aducanumab and lithium on cognitive function in mild cognitive impairment and Alzheimer's disease: A systematic review and network meta-analysis}},
  journal = {Ageing research reviews},
  year    = {2024},
  doi     = {10.1016/j.arr.2024.102203},
  pmid    = {38253184},
  url     = {https://doi.org/10.1016/j.arr.2024.102203}
}

@article{terao2025-40386876,
  author  = {Terao, Itsuki and Kodama, Wakako},
  title   = {{Comparative efficacy, tolerability, and acceptability of aducanumab, lecanemab, and donanemab with repetitive transcranial magnetic stimulation on cognitive function in mild cognitive impairment and Alzheimer's disease: A systematic review and network meta-analysis}},
  journal = {Journal of psychopharmacology (Oxford, England)},
  year    = {2025},
  doi     = {10.1177/02698811251340901},
  pmid    = {40386876},
  url     = {https://doi.org/10.1177/02698811251340901}
}

@article{deng2024-39312316,
  author  = {Deng, Xiaoyan and Li, Daishun},
  title   = {{Effect of long-term pharmacological treatments on Alzheimer disease: A systematic review and network meta-analysis}},
  journal = {Medicine},
  year    = {2024},
  doi     = {10.1097/md.0000000000039753},
  pmid    = {39312316},
  url     = {https://doi.org/10.1097/md.0000000000039753}
}

@article{costa2022-34942135,
  author  = {Costa, Alberto C S and Brandão, Ana C and Boada, Richard and Barrionuevo, Veridiana L and Taylor, Hudson G and Roth, Elizabeth and Stasko, Melissa R and Johnson, Mark W and others},
  title   = {{Safety, efficacy, and tolerability of memantine for cognitive and adaptive outcome measures in adolescents and young adults with Down syndrome: a randomised, double-blind, placebo-controlled phase 2 trial}},
  journal = {The Lancet. Neurology},
  year    = {2022},
  doi     = {10.1016/s1474-4422(21)00369-0},
  pmid    = {34942135},
  url     = {https://doi.org/10.1016/s1474-4422(21)00369-0}
}

@article{cummings2026-c800c391,
  author  = {Cummings, J. L. and Atri, A. and Scheltens, P. and others},
  title   = {{Efficacy and safety of oral semaglutide 14 mg (flexible dose) in early-stage symptomatic Alzheimer's disease (EVOKE and EVOKE+): two phase 3, randomised, placebo-controlled trials}},
  journal = {The Lancet},
  year    = {2026},
  doi     = {10.1016/s0140-6736(26)00459-9},
  pmid    = {41865758},
  url     = {https://doi.org/10.1016/s0140-6736(26)00459-9}
}

@article{tariot2004-14734594,
  author  = {Tariot, P. N. and Farlow, M. R. and Grossberg, G. T. and Graham, S. M. and McDonald, S. and Gergel, I. and {Memantine Study Group}},
  title   = {{Memantine treatment in patients with moderate to severe Alzheimer disease already receiving donepezil: a randomized controlled trial}},
  journal = {JAMA},
  year    = {2004},
  doi     = {10.1001/jama.291.3.317},
  pmid    = {14734594},
  url     = {https://doi.org/10.1001/jama.291.3.317}
}

@article{swanson2021-33865446,
  author  = {Swanson, C. J. and Zhang, Y. and Dhadda, S. and Wang, J. and Kaplow, J. and Lai, R. Y. K. and Lannfelt, L. and Bradley, H. and others},
  title   = {{A randomized, double-blind, phase 2b proof-of-concept clinical trial in early Alzheimer's disease with lecanemab, an anti-Aβ protofibril antibody}},
  journal = {Alzheimer's research \& therapy},
  year    = {2021},
  doi     = {10.1186/s13195-021-00813-8},
  pmid    = {33865446},
  url     = {https://doi.org/10.1186/s13195-021-00813-8}
}

@article{cummings2025-39780249,
  author  = {Cummings, J. L. and Atri, A. and Feldman, H. H. and Hansson, O. and Sano, M. and Knop, F. K. and Johannsen, P. and León, T. and others},
  title   = {{evoke and evoke+: design of two large-scale, double-blind, placebo-controlled, phase 3 studies evaluating efficacy, safety, and tolerability of semaglutide in early-stage symptomatic Alzheimer's disease}},
  journal = {Alzheimer's research \& therapy},
  year    = {2025},
  doi     = {10.1186/s13195-024-01666-7},
  pmid    = {39780249},
  url     = {https://doi.org/10.1186/s13195-024-01666-7}
}

@article{mcdade2022-36544184,
  author  = {McDade, E. and Cummings, J. L. and Dhadda, S. and Swanson, C. J. and Reyderman, L. and Kanekiyo, M. and Koyama, A. and Irizarry, M. and others},
  title   = {{Lecanemab in patients with early Alzheimer's disease: detailed results on biomarker, cognitive, and clinical effects from the randomized and open-label extension of the phase 2 proof-of-concept study}},
  journal = {Alzheimer's research \& therapy},
  year    = {2022},
  doi     = {10.1186/s13195-022-01124-2},
  pmid    = {36544184},
  url     = {https://doi.org/10.1186/s13195-022-01124-2}
}

@article{wu2023-38017568,
  author  = {Wu, W. and Ji, Y. and Wang, Z. and Wu, X. and Li, J. and Gu, F. and Chen, Z.},
  title   = {{The FDA-approved anti-amyloid-β monoclonal antibodies for the treatment of Alzheimer's disease: a systematic review and meta-analysis of randomized controlled trials}},
  journal = {European journal of medical research},
  year    = {2023},
  doi     = {10.1186/s40001-023-01512-w},
  pmid    = {38017568},
  url     = {https://doi.org/10.1186/s40001-023-01512-w}
}

@article{winblad2001-11502918,
  author  = {Winblad, B. and Engedal, K. and Soininen, H. and Verhey, F. and Waldemar, G. and Wimo, A. and Wetterholm, A. L. and Zhang, R. and others},
  title   = {{A 1-year, randomized, placebo-controlled study of donepezil in patients with mild to moderate AD}},
  journal = {Neurology},
  year    = {2001},
  doi     = {10.1212/wnl.57.3.489},
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