% alzhub.org library filter
% Source: https://alzhub.org/research?category=genetics&about=risk-factors
% 236 entries, in the order the page lists them. Built from alzhub.org's own records.
% 1 entries have no readable author in the source record and carry no author field.

@article{lacour2017-26976043,
  author  = {Lacour, A. and Espinosa, A. and Louwersheimer, E. and Heilmann, S. and Hernández, I. and Wolfsgruber, S. and Fernández, V. and Wagner, H. and others},
  title   = {{Genome-wide significant risk factors for Alzheimer's disease: role in progression to dementia due to Alzheimer's disease among subjects with mild cognitive impairment}},
  journal = {Molecular psychiatry},
  year    = {2017},
  doi     = {10.1038/mp.2016.18},
  pmid    = {26976043},
  url     = {https://doi.org/10.1038/mp.2016.18}
}

@article{fransquet2019-30975202,
  author  = {Fransquet, P. D. and Wrigglesworth, J. and Woods, R. L. and Ernst, M. E. and Ryan, J.},
  title   = {{The epigenetic clock as a predictor of disease and mortality risk: a systematic review and meta-analysis}},
  journal = {Clinical epigenetics},
  year    = {2019},
  doi     = {10.1186/s13148-019-0656-7},
  pmid    = {30975202},
  url     = {https://doi.org/10.1186/s13148-019-0656-7}
}

@article{study2024-39046104,
  title   = {{A genome-wide association meta-analysis of all-cause and vascular dementia}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2024},
  doi     = {10.1002/alz.14115},
  pmid    = {39046104},
  url     = {https://doi.org/10.1002/alz.14115}
}

@article{littlejohns2017-28531320,
  author  = {Littlejohns, Thomas J. and Sudlow, Cathie L. M. and Allen, Naomi E. and Collins, Rory},
  title   = {{UK Biobank: opportunities for cardiovascular research}},
  journal = {European Heart Journal},
  year    = {2017},
  doi     = {10.1093/eurheartj/ehx254},
  pmid    = {28531320},
  url     = {https://doi.org/10.1093/eurheartj/ehx254}
}

@article{darst2017-27662287,
  author  = {Darst, B. F. and Koscik, R. L. and Racine, A. M. and Oh, J. M. and Krause, R. A. and Carlsson, C. M. and Zetterberg, H. and Blennow, K. and others},
  title   = {{Pathway-Specific Polygenic Risk Scores as Predictors of Amyloid-β Deposition and Cognitive Function in a Sample at Increased Risk for Alzheimer's Disease}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2017},
  doi     = {10.3233/jad-160195},
  pmid    = {27662287},
  url     = {https://doi.org/10.3233/jad-160195}
}

@article{liu2014-24231519,
  author  = {Liu, G. and Yao, L. and Liu, J. and Jiang, Y. and Ma, G. and Chen, Z. and Zhao, B. and others},
  title   = {{Cardiovascular disease contributes to Alzheimer's disease: evidence from large-scale genome-wide association studies}},
  journal = {Neurobiology of aging},
  year    = {2014},
  doi     = {10.1016/j.neurobiolaging.2013.10.084},
  pmid    = {24231519},
  url     = {https://doi.org/10.1016/j.neurobiolaging.2013.10.084}
}

@article{gottesman2017-28399252,
  author  = {Gottesman, R. F. and Schneider, A. L. and Zhou, Y. and Coresh, J. and Green, E. and Gupta, N. and Knopman, D. S. and Mintz, A. and others},
  title   = {{Association Between Midlife Vascular Risk Factors and Estimated Brain Amyloid Deposition}},
  journal = {JAMA},
  year    = {2017},
  doi     = {10.1001/jama.2017.3090},
  pmid    = {28399252},
  url     = {https://doi.org/10.1001/jama.2017.3090}
}

@article{altmann2014-24623176,
  author  = {Altmann, A. and Tian, L. and Henderson, V. W. and Greicius, M. D. and {Alzheimer's Disease Neuroimaging Initiative Investigators}},
  title   = {{Sex modifies the APOE-related risk of developing Alzheimer disease}},
  journal = {Annals of neurology},
  year    = {2014},
  doi     = {10.1002/ana.24135},
  pmid    = {24623176},
  url     = {https://doi.org/10.1002/ana.24135}
}

@article{neu2017-28846757,
  author  = {Neu, S. C. and Pa, J. and Kukull, W. and Beekly, D. and Kuzma, A. and Gangadharan, P. and Wang, L. S. and Romero, K. and others},
  title   = {{Apolipoprotein E Genotype and Sex Risk Factors for Alzheimer Disease: A Meta-analysis}},
  journal = {JAMA neurology},
  year    = {2017},
  doi     = {10.1001/jamaneurol.2017.2188},
  pmid    = {28846757},
  url     = {https://doi.org/10.1001/jamaneurol.2017.2188}
}

@article{leguen2023-36809323,
  author  = {Le Guen, Y. and Raulin, A. C. and Logue, M. W. and Sherva, R. and Belloy, M. E. and Eger, S. J. and Chen, A. and Kennedy, G. and Kuchenbecker, L. and O'Leary, J. P. and Zhang, R. and Merritt, V. C. and others},
  title   = {{Association of African Ancestry-Specific APOE Missense Variant R145C With Risk of Alzheimer Disease}},
  journal = {JAMA},
  year    = {2023},
  doi     = {10.1001/jama.2023.0268},
  pmid    = {36809323},
  url     = {https://doi.org/10.1001/jama.2023.0268}
}

@article{barbergergateau2007-17998483,
  author  = {Barberger-Gateau, P. and Raffaitin, C. and Letenneur, L. and Berr, C. and Tzourio, C. and Dartigues, J. F. and Alpérovitch, A.},
  title   = {{Dietary patterns and risk of dementia: the Three-City cohort study}},
  journal = {Neurology},
  year    = {2007},
  doi     = {10.1212/01.wnl.0000278116.37320.52},
  pmid    = {17998483},
  url     = {https://doi.org/10.1212/01.wnl.0000278116.37320.52}
}

@article{tang1996-8709781,
  author  = {Tang, M. X. and Jacobs, D. and Stern, Y. and Marder, K. and Schofield, P. and Gurland, B. and Andrews, H. and Mayeux, R.},
  title   = {{Effect of oestrogen during menopause on risk and age at onset of Alzheimer's disease}},
  journal = {Lancet (London, England)},
  year    = {1996},
  doi     = {10.1016/s0140-6736(96)03356-9},
  pmid    = {8709781},
  url     = {https://doi.org/10.1016/s0140-6736(96)03356-9}
}

@article{ma2024-38592337,
  author  = {Ma, Xiao-Na and Feng, Wei and Chen, Shu-Lin and Zhong, Xiao-Qin and Lin, Chang-Song and Xu, Qiang},
  title   = {{Methotrexate and the Risk of Dementia: A Two-Sample Mendelian Randomization Study}},
  journal = {Neurology and therapy},
  year    = {2024},
  doi     = {10.1007/s40120-024-00609-6},
  pmid    = {38592337},
  url     = {https://doi.org/10.1007/s40120-024-00609-6}
}

@article{mccartney2018-30167451,
  author  = {McCartney, D. L. and Stevenson, A. J. and Walker, R. M. and Gibson, J. and Morris, S. W. and Campbell, A. and Murray, A. D. and Whalley, H. C. and others},
  title   = {{Investigating the relationship between DNA methylation age acceleration and risk factors for Alzheimer's disease}},
  journal = {Alzheimer's \& dementia (Amsterdam, Netherlands)},
  year    = {2018},
  doi     = {10.1016/j.dadm.2018.05.006},
  pmid    = {30167451},
  url     = {https://doi.org/10.1016/j.dadm.2018.05.006}
}

@article{tang1998-9508150,
  author  = {Tang, M. X. and Stern, Y. and Marder, K. and Bell, K. and Gurland, B. and Lantigua, R. and Andrews, H. and Feng, L. and others},
  title   = {{The APOE-epsilon4 allele and the risk of Alzheimer disease among African Americans, whites, and Hispanics}},
  journal = {JAMA},
  year    = {1998},
  doi     = {10.1001/jama.279.10.751},
  pmid    = {9508150},
  url     = {https://doi.org/10.1001/jama.279.10.751}
}

@article{sargurupremraj2020-33293549,
  author  = {Sargurupremraj, M. and Suzuki, H. and Jian, X. and Sarnowski, C. and Evans, T. E. and Bis, J. C. and Eiriksdottir, G. and Sakaue, S. and others},
  title   = {{Cerebral small vessel disease genomics and its implications across the lifespan}},
  journal = {Nature communications},
  year    = {2020},
  doi     = {10.1038/s41467-020-19111-2},
  pmid    = {33293549},
  url     = {https://doi.org/10.1038/s41467-020-19111-2}
}

@article{hithersay2019-30452522,
  author  = {Hithersay, R. and Startin, C. M. and Hamburg, S. and Mok, K. Y. and Hardy, J. and Fisher, E. M. C. and Tybulewicz, V. L. J. and Nizetic, D. and others},
  title   = {{Association of Dementia With Mortality Among Adults With Down Syndrome Older Than 35 Years}},
  journal = {JAMA neurology},
  year    = {2019},
  doi     = {10.1001/jamaneurol.2018.3616},
  pmid    = {30452522},
  url     = {https://doi.org/10.1001/jamaneurol.2018.3616}
}

@article{salinas2022-35131906,
  author  = {Salinas, J. and Beiser, A. S. and Samra, J. K. and O'Donnell, A. and DeCarli, C. S. and Gonzales, M. M. and Aparicio, H. J. and Seshadri, S.},
  title   = {{Association of Loneliness With 10-Year Dementia Risk and Early Markers of Vulnerability for Neurocognitive Decline}},
  journal = {Neurology},
  year    = {2022},
  doi     = {10.1212/wnl.0000000000200039},
  pmid    = {35131906},
  url     = {https://doi.org/10.1212/wnl.0000000000200039}
}

@article{luchsinger2007-17420320,
  author  = {Luchsinger, J. A. and Reitz, C. and Patel, B. and Tang, M. X. and Manly, J. J. and Mayeux, R.},
  title   = {{Relation of diabetes to mild cognitive impairment}},
  journal = {Archives of neurology},
  year    = {2007},
  doi     = {10.1001/archneur.64.4.570},
  pmid    = {17420320},
  url     = {https://doi.org/10.1001/archneur.64.4.570}
}

@article{slooter1998-9678314,
  author  = {Slooter, A. J. and Cruts, M. and Kalmijn, S. and Hofman, A. and Breteler, M. M. and Van Broeckhoven, C. and van Duijn, C. M.},
  title   = {{Risk estimates of dementia by apolipoprotein E genotypes from a population-based incidence study: the Rotterdam Study}},
  journal = {Archives of neurology},
  year    = {1998},
  doi     = {10.1001/archneur.55.7.964},
  pmid    = {9678314},
  url     = {https://doi.org/10.1001/archneur.55.7.964}
}

@article{farnsworthvoncederwald2022-35444051,
  author  = {Farnsworth von Cederwald, B. and Josefsson, M. and Wåhlin, A. and Nyberg, L. and Karalija, N.},
  title   = {{Association of Cardiovascular Risk Trajectory With Cognitive Decline and Incident Dementia}},
  journal = {Neurology},
  year    = {2022},
  doi     = {10.1212/wnl.0000000000200255},
  pmid    = {35444051},
  url     = {https://doi.org/10.1212/wnl.0000000000200255}
}

@article{broce2019-30413934,
  author  = {Broce, I. J. and Tan, C. H. and Fan, C. C. and Jansen, I. and Savage, J. E. and Witoelar, A. and Wen, N. and Hess, C. P. and others},
  title   = {{Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer's disease}},
  journal = {Acta neuropathologica},
  year    = {2019},
  doi     = {10.1007/s00401-018-1928-6},
  pmid    = {30413934},
  url     = {https://doi.org/10.1007/s00401-018-1928-6}
}

@article{szekely2008-18003940,
  author  = {Szekely, C. A. and Breitner, J. C. and Fitzpatrick, A. L. and Rea, T. D. and Psaty, B. M. and Kuller, L. H. and Zandi, P. P.},
  title   = {{NSAID use and dementia risk in the Cardiovascular Health Study: role of APOE and NSAID type}},
  journal = {Neurology},
  year    = {2008},
  doi     = {10.1212/01.wnl.0000284596.95156.48},
  pmid    = {18003940},
  url     = {https://doi.org/10.1212/01.wnl.0000284596.95156.48}
}

@article{bettens2012-22248099,
  author  = {Bettens, K. and Brouwers, N. and Engelborghs, S. and Lambert, J. C. and Rogaeva, E. and Vandenberghe, R. and Le Bastard, N. and Pasquier, F. and others},
  title   = {{Both common variations and rare non-synonymous substitutions and small insertion/deletions in CLU are associated with increased Alzheimer risk}},
  journal = {Molecular neurodegeneration},
  year    = {2012},
  doi     = {10.1186/1750-1326-7-3},
  pmid    = {22248099},
  url     = {https://doi.org/10.1186/1750-1326-7-3}
}

@article{saadmaan2026-40747850,
  author  = {Saadmaan, Gazi and Dalmasso, Maria Carolina and Maria, Maleeha and Lehtisalo, Jenni and Hiltunen, Mikko and Kaikkonen, Minna U and Levälahti, Esko and Mangialasche, Francesca and others},
  title   = {{Alzheimer and cardiovascular genetic scores and cognition: the FINGER randomized controlled trial}},
  journal = {Brain : a journal of neurology},
  year    = {2026},
  doi     = {10.1093/brain/awaf277},
  pmid    = {40747850},
  url     = {https://doi.org/10.1093/brain/awaf277}
}

@article{schilling2017-28350817,
  author  = {Schilling, S. and Tzourio, C. and Soumaré, A. and Kaffashian, S. and Dartigues, J. F. and Ancelin, M. L. and Samieri, C. and Dufouil, C. and others},
  title   = {{Differential associations of plasma lipids with incident dementia and dementia subtypes in the 3C Study: A longitudinal, population-based prospective cohort study}},
  journal = {PLoS medicine},
  year    = {2017},
  doi     = {10.1371/journal.pmed.1002265},
  pmid    = {28350817},
  url     = {https://doi.org/10.1371/journal.pmed.1002265}
}

@article{leguen2022-35639372,
  author  = {Le Guen, Y. and Belloy, M. E. and Grenier-Boley, B. and de Rojas, I. and Castillo-Morales, A. and Jansen, I. and Nicolas, A. and Bellenguez, C. and others},
  title   = {{Association of Rare APOE Missense Variants V236E and R251G With Risk of Alzheimer Disease}},
  journal = {JAMA neurology},
  year    = {2022},
  doi     = {10.1001/jamaneurol.2022.1166},
  pmid    = {35639372},
  url     = {https://doi.org/10.1001/jamaneurol.2022.1166}
}

@article{oh2025-40634782,
  author  = {Oh, H. S. and Le Guen, Y. and Rappoport, N. and Urey, D. Y. and Farinas, A. and Rutledge, J. and Channappa, D. and Wagner, A. D. and others},
  title   = {{Plasma proteomics links brain and immune system aging with healthspan and longevity}},
  journal = {Nature medicine},
  year    = {2025},
  doi     = {10.1038/s41591-025-03798-1},
  pmid    = {40634782},
  url     = {https://doi.org/10.1038/s41591-025-03798-1}
}

@article{rajan2024-38447103,
  author  = {Rajan, K. B. and Mcaninch, E. A. and Wilson, R. S. and Dhana, A. and Evans-Lacko, S. and Evans, D. A.},
  title   = {{Statin Initiation and Risk of Incident Alzheimer Disease and Cognitive Decline in Genetically Susceptible Older Adults}},
  journal = {Neurology},
  year    = {2024},
  doi     = {10.1212/WNL.0000000000209168},
  pmid    = {38447103},
  url     = {https://doi.org/10.1212/WNL.0000000000209168}
}

@article{solomon2007-17339582,
  author  = {Solomon, A. and Kåreholt, I. and Ngandu, T. and Winblad, B. and Nissinen, A. and Tuomilehto, J. and Soininen, H. and Kivipelto, M.},
  title   = {{Serum cholesterol changes after midlife and late-life cognition: twenty-one-year follow-up study}},
  journal = {Neurology},
  year    = {2007},
  doi     = {10.1212/01.wnl.0000256368.57375.b7},
  pmid    = {17339582},
  url     = {https://doi.org/10.1212/01.wnl.0000256368.57375.b7}
}

@article{slooter1997-9052712,
  author  = {Slooter, A. J. and Tang, M. X. and van Duijn, C. M. and Stern, Y. and Ott, A. and Bell, K. and Breteler, M. M. and Van Broeckhoven, C. and others},
  title   = {{Apolipoprotein E epsilon4 and the risk of dementia with stroke. A population-based investigation}},
  journal = {JAMA},
  year    = {1997},
  doi     = {10.1001/jama.277.10.818},
  pmid    = {9052712},
  url     = {https://doi.org/10.1001/jama.277.10.818}
}

@article{raptis2025-41286463,
  author  = {Raptis, Vasilis and Bhak, Youngjune and Cannings, Timothy I. and MacLullich, Alasdair M. J. and Tenesa, Albert},
  title   = {{Dissecting the genetic and proteomic risk factors for delirium}},
  journal = {Nature Aging},
  year    = {2025},
  doi     = {10.1038/s43587-025-01018-6},
  pmid    = {41286463},
  url     = {https://doi.org/10.1038/s43587-025-01018-6}
}

@article{zhong2015-25763939,
  author  = {Zhong, G. and Wang, Y. and Zhang, Y. and Guo, J. J. and Zhao, Y.},
  title   = {{Smoking is associated with an increased risk of dementia: a meta-analysis of prospective cohort studies with investigation of potential effect modifiers}},
  journal = {PloS one},
  year    = {2015},
  doi     = {10.1371/journal.pone.0118333},
  pmid    = {25763939},
  url     = {https://doi.org/10.1371/journal.pone.0118333}
}

@article{daoust2025-40042447,
  author  = {D'Aoust, T. and Clocchiatti-Tuozzo, S. and Rivier, C. A. and Mishra, A. and Hachiya, T. and Grenier-Boley, B. and Soumaré, A. and Duperron, M. G. and Le Grand, Q. and Bouteloup, V. and Proust-Lima, C. and Samieri, C. and others},
  title   = {{Polygenic score integrating neurodegenerative and vascular risk informs dementia risk stratification}},
  journal = {Alzheimer's \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz.70014},
  pmid    = {40042447},
  url     = {https://doi.org/10.1002/alz.70014}
}

@article{schrijvers2010-21115952,
  author  = {Schrijvers, E. M. and Witteman, J. C. and Sijbrands, E. J. and Hofman, A. and Koudstaal, P. J. and Breteler, M. M.},
  title   = {{Insulin metabolism and the risk of Alzheimer disease: the Rotterdam Study}},
  journal = {Neurology},
  year    = {2010},
  doi     = {10.1212/wnl.0b013e3181ffe4f6},
  pmid    = {21115952},
  url     = {https://doi.org/10.1212/wnl.0b013e3181ffe4f6}
}

@article{roe2010-20032288,
  author  = {Roe, C. M. and Fitzpatrick, A. L. and Xiong, C. and Sieh, W. and Kuller, L. and Miller, J. P. and Williams, M. M. and Kopan, R. and others},
  title   = {{Cancer linked to Alzheimer disease but not vascular dementia}},
  journal = {Neurology},
  year    = {2010},
  doi     = {10.1212/wnl.0b013e3181c91873},
  pmid    = {20032288},
  url     = {https://doi.org/10.1212/wnl.0b013e3181c91873}
}

@article{holland2020-31996451,
  author  = {Holland, T. M. and Agarwal, P. and Wang, Y. and Leurgans, S. E. and Bennett, D. A. and Booth, S. L. and Morris, M. C.},
  title   = {{Dietary flavonols and risk of Alzheimer dementia}},
  journal = {Neurology},
  year    = {2020},
  doi     = {10.1212/wnl.0000000000008981},
  pmid    = {31996451},
  url     = {https://doi.org/10.1212/wnl.0000000000008981}
}

@article{weuve2018-28863046,
  author  = {Weuve, J. and Barnes, L. L. and Mendes de Leon, C. F. and Rajan, K. B. and Beck, T. and Aggarwal, N. T. and Hebert, L. E. and Bennett, D. A. and others},
  title   = {{Cognitive Aging in Black and White Americans: Cognition, Cognitive Decline, and Incidence of Alzheimer Disease Dementia}},
  journal = {Epidemiology (Cambridge, Mass.)},
  year    = {2018},
  doi     = {10.1097/ede.0000000000000747},
  pmid    = {28863046},
  url     = {https://doi.org/10.1097/ede.0000000000000747}
}

@article{lim2013-24145819,
  author  = {Lim, A. S. and Yu, L. and Kowgier, M. and Schneider, J. A. and Buchman, A. S. and Bennett, D. A.},
  title   = {{Modification of the relationship of the apolipoprotein E ε4 allele to the risk of Alzheimer disease and neurofibrillary tangle density by sleep}},
  journal = {JAMA neurology},
  year    = {2013},
  doi     = {10.1001/jamaneurol.2013.4215},
  pmid    = {24145819},
  url     = {https://doi.org/10.1001/jamaneurol.2013.4215}
}

@article{wang2006-16717174,
  author  = {Wang, L. and Larson, E. B. and Bowen, J. D. and van Belle, G.},
  title   = {{Performance-based physical function and future dementia in older people}},
  journal = {Archives of internal medicine},
  year    = {2006},
  doi     = {10.1001/archinte.166.10.1115},
  pmid    = {16717174},
  url     = {https://doi.org/10.1001/archinte.166.10.1115}
}

@article{habes2018-30076276,
  author  = {Habes, M. and Sotiras, A. and Erus, G. and Toledo, J. B. and Janowitz, D. and Wolk, D. A. and Shou, H. and Bryan, N. R. and others},
  title   = {{White matter lesions: Spatial heterogeneity, links to risk factors, cognition, genetics, and atrophy}},
  journal = {Neurology},
  year    = {2018},
  doi     = {10.1212/wnl.0000000000006116},
  pmid    = {30076276},
  url     = {https://doi.org/10.1212/wnl.0000000000006116}
}

@article{vemuri2017-28418521,
  author  = {Vemuri, P. and Knopman, D. S. and Lesnick, T. G. and Przybelski, S. A. and Mielke, M. M. and Graff-Radford, J. and Murray, M. E. and Roberts, R. O. and others},
  title   = {{Evaluation of Amyloid Protective Factors and Alzheimer Disease Neurodegeneration Protective Factors in Elderly Individuals}},
  journal = {JAMA neurology},
  year    = {2017},
  doi     = {10.1001/jamaneurol.2017.0244},
  pmid    = {28418521},
  url     = {https://doi.org/10.1001/jamaneurol.2017.0244}
}

@article{zhang2021-33748832,
  author  = {Zhang, H. and Greenwood, D. C. and Risch, H. A. and Bunce, D. and Hardie, L. J. and Cade, J. E.},
  title   = {{Meat consumption and risk of incident dementia: cohort study of 493,888 UK Biobank participants}},
  journal = {The American journal of clinical nutrition},
  year    = {2021},
  doi     = {10.1093/ajcn/nqab028},
  pmid    = {33748832},
  url     = {https://doi.org/10.1093/ajcn/nqab028}
}

@article{steele2017-28350795,
  author  = {Steele, N. Z. and Carr, J. S. and Bonham, L. W. and Geier, E. G. and Damotte, V. and Miller, Z. A. and Desikan, R. S. and Boehme, K. L. and others},
  title   = {{Fine-mapping of the human leukocyte antigen locus as a risk factor for Alzheimer disease: A case-control study}},
  journal = {PLoS medicine},
  year    = {2017},
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