% alzhub.org library filter % Source: https://alzhub.org/research?category=genetics_trem2&author=Li+X&about=genetics % 12 entries, in the order the page lists them. Built from alzhub.org's own records. % 0 entries have no readable author in the source record and carry no author field. @article{li2015-26202100, author = {Li, X. and Long, J. and He, T. and Belshaw, R. and Scott, J.}, title = {{Integrated genomic approaches identify major pathways and upstream regulators in late onset Alzheimer's disease}}, journal = {Scientific reports}, year = {2015}, doi = {10.1038/srep12393}, pmid = {26202100}, url = {https://doi.org/10.1038/srep12393} } @article{zhao2018-29518356, author = {Zhao, Y. and Wu, X. and Li, X. and Jiang, L. L. and Gui, X. and Liu, Y. and Sun, Y. and Zhu, B. and others}, title = {{TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function}}, journal = {Neuron}, year = {2018}, doi = {10.1016/j.neuron.2018.01.031}, pmid = {29518356}, url = {https://doi.org/10.1016/j.neuron.2018.01.031} } @article{lee2018-29518357, author = {Lee, C. Y. D. and Daggett, A. and Gu, X. and Jiang, L. L. and Langfelder, P. and Li, X. and Wang, N. and Zhao, Y. and others}, title = {{Elevated TREM2 Gene Dosage Reprograms Microglia Responsivity and Ameliorates Pathological Phenotypes in Alzheimer's Disease Models}}, journal = {Neuron}, year = {2018}, doi = {10.1016/j.neuron.2018.02.002}, pmid = {29518357}, url = {https://doi.org/10.1016/j.neuron.2018.02.002} } @article{zhao2022-36070367, author = {Zhao, P. and Xu, Y. and Jiang, L. and Fan, X. and Li, L. and Li, X. and Arase, H. and Zhao, Y. and others}, title = {{A tetravalent TREM2 agonistic antibody reduced amyloid pathology in a mouse model of Alzheimer's disease}}, journal = {Science translational medicine}, year = {2022}, doi = {10.1126/scitranslmed.abq0095}, pmid = {36070367}, url = {https://doi.org/10.1126/scitranslmed.abq0095} } @article{liu2020-32941599, author = {Liu, T. and Zhu, B. and Liu, Y. and Zhang, X. and Yin, J. and Li, X. and Jiang, L. and Hodges, A. P. and others}, title = {{Multi-omic comparison of Alzheimer's variants in human ESC-derived microglia reveals convergence at APOE}}, journal = {The Journal of experimental medicine}, year = {2020}, doi = {10.1084/jem.20200474}, pmid = {32941599}, url = {https://doi.org/10.1084/jem.20200474} } @article{wu2017-28592261, author = {Wu, R. and Li, X. and Xu, P. and Huang, L. and Cheng, J. and Huang, X. and Jiang, J. and Wu, L. J. and others}, title = {{TREM2 protects against cerebral ischemia/reperfusion injury}}, journal = {Molecular brain}, year = {2017}, doi = {10.1186/s13041-017-0296-9}, pmid = {28592261}, url = {https://doi.org/10.1186/s13041-017-0296-9} } @article{zheng2018-30532704, author = {Zheng, H. and Cheng, B. and Li, Y. and Li, X. and Chen, X. and Zhang, Y. W.}, title = {{TREM2 in Alzheimer's Disease: Microglial Survival and Energy Metabolism}}, journal = {Frontiers in aging neuroscience}, year = {2018}, doi = {10.3389/fnagi.2018.00395}, pmid = {30532704}, url = {https://doi.org/10.3389/fnagi.2018.00395} } @article{zhong2017-28680398, author = {Zhong, L. and Zhang, Z. L. and Li, X. and Liao, C. and Mou, P. and Wang, T. and Wang, Z. and others}, title = {{TREM2/DAP12 Complex Regulates Inflammatory Responses in Microglia via the JNK Signaling Pathway}}, journal = {Frontiers in aging neuroscience}, year = {2017}, doi = {10.3389/fnagi.2017.00204}, pmid = {28680398}, url = {https://doi.org/10.3389/fnagi.2017.00204} } @article{zhao2022-35921534, author = {Zhao, P. and Xu, Y. and Fan, X. and Li, L. and Li, X. and Arase, H. and Tong, Q. and Zhang, N. and others}, title = {{Discovery and engineering of an anti-TREM2 antibody to promote amyloid plaque clearance by microglia in 5XFAD mice}}, journal = {mAbs}, year = {2022}, doi = {10.1080/19420862.2022.2107971}, pmid = {35921534}, url = {https://doi.org/10.1080/19420862.2022.2107971} } @article{lan2022-35367455, author = {Lan, L. and Wang, H. and Zhang, X. and Shen, Q. and Li, X. and He, L. and Rong, X. and Peng, J. and others}, title = {{Chronic exposure of alcohol triggers microglia-mediated synaptic elimination inducing cognitive impairment}}, journal = {Experimental neurology}, year = {2022}, doi = {10.1016/j.expneurol.2022.114061}, pmid = {35367455}, url = {https://doi.org/10.1016/j.expneurol.2022.114061} } @article{jiang2018-29689568, author = {Jiang, Y. and Li, Z. and Ma, H. and Cao, X. and Liu, F. and Tian, A. and Sun, X. and Li, X. and others}, title = {{Upregulation of TREM2 Ameliorates Neuroinflammatory Responses and Improves Cognitive Deficits Triggered by Surgical Trauma in Appswe/PS1dE9 Mice}}, journal = {Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology}, year = {2018}, doi = {10.1159/000489155}, pmid = {29689568}, url = {https://doi.org/10.1159/000489155} } @article{rong2020-32613609, author = {Rong, Z. and Cheng, B. and Zhong, L. and Ye, X. and Li, X. and Jia, L. and Li, Y. and Shue, F. and others}, title = {{Activation of FAK/Rac1/Cdc42-GTPase signaling ameliorates impaired microglial migration response to Aβ42 in triggering receptor expressed on myeloid cells 2 loss-of-function murine models}}, journal = {FASEB journal : official publication of the Federation of American Societies for Experimental Biology}, year = {2020}, doi = {10.1096/fj.202000550rr}, pmid = {32613609}, url = {https://doi.org/10.1096/fj.202000550rr} }