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% Source: https://alzhub.org/research?author=Holtzman+DM&about=genetics
% 27 entries, in the order the page lists them. Built from alzhub.org's own records.
% 0 entries have no readable author in the source record and carry no author field.

@article{piccio2016-26754641,
  author  = {Piccio, L. and Deming, Y. and Del-Águila, J. L. and Ghezzi, L. and Holtzman, D. M. and Fagan, A. M. and Fenoglio, C. and Galimberti, D. and others},
  title   = {{Cerebrospinal fluid soluble TREM2 is higher in Alzheimer disease and associated with mutation status}},
  journal = {Acta neuropathologica},
  year    = {2016},
  doi     = {10.1007/s00401-016-1533-5},
  pmid    = {26754641},
  url     = {https://doi.org/10.1007/s00401-016-1533-5}
}

@article{morris2010-20186853,
  author  = {Morris, J. C. and Roe, C. M. and Xiong, C. and Fagan, A. M. and Goate, A. M. and Holtzman, D. M. and Mintun, M. A.},
  title   = {{APOE predicts amyloid-beta but not tau Alzheimer pathology in cognitively normal aging}},
  journal = {Annals of neurology},
  year    = {2010},
  doi     = {10.1002/ana.21843},
  pmid    = {20186853},
  url     = {https://doi.org/10.1002/ana.21843}
}

@article{bell2012-22622580,
  author  = {Bell, R. D. and Winkler, E. A. and Singh, I. and Sagare, A. P. and Deane, R. and Wu, Z. and Holtzman, D. M. and Betsholtz, C. and others},
  title   = {{Apolipoprotein E controls cerebrovascular integrity via cyclophilin A}},
  journal = {Nature},
  year    = {2012},
  doi     = {10.1038/nature11087},
  pmid    = {22622580},
  url     = {https://doi.org/10.1038/nature11087}
}

@article{mishra2018-29672664,
  author  = {Mishra, S. and Blazey, T. M. and Holtzman, D. M. and Cruchaga, C. and Su, Y. and Morris, J. C. and Benzinger, T. L. S. and Gordon, B. A.},
  title   = {{Longitudinal brain imaging in preclinical Alzheimer disease: impact of APOE ε4 genotype}},
  journal = {Brain : a journal of neurology},
  year    = {2018},
  doi     = {10.1093/brain/awy103},
  pmid    = {29672664},
  url     = {https://doi.org/10.1093/brain/awy103}
}

@article{thomas2014-25069482,
  author  = {Thomas, J. B. and Brier, M. R. and Bateman, R. J. and Snyder, A. Z. and Benzinger, T. L. and Xiong, C. and Raichle, M. and Holtzman, D. M. and others},
  title   = {{Functional connectivity in autosomal dominant and late-onset Alzheimer disease}},
  journal = {JAMA neurology},
  year    = {2014},
  doi     = {10.1001/jamaneurol.2014.1654},
  pmid    = {25069482},
  url     = {https://doi.org/10.1001/jamaneurol.2014.1654}
}

@article{hu2012-22855860,
  author  = {Hu, W. T. and Holtzman, D. M. and Fagan, A. M. and Shaw, L. M. and Perrin, R. and Arnold, S. E. and Grossman, M. and Xiong, C. and others},
  title   = {{Plasma multianalyte profiling in mild cognitive impairment and Alzheimer disease}},
  journal = {Neurology},
  year    = {2012},
  doi     = {10.1212/wnl.0b013e318266fa70},
  pmid    = {22855860},
  url     = {https://doi.org/10.1212/wnl.0b013e318266fa70}
}

@article{martens2022-35298921,
  author  = {Martens, Y. A. and Zhao, N. and Liu, C. C. and Kanekiyo, T. and Yang, A. J. and Goate, A. M. and Holtzman, D. M. and Bu, G.},
  title   = {{ApoE Cascade Hypothesis in the pathogenesis of Alzheimer's disease and related dementias}},
  journal = {Neuron},
  year    = {2022},
  doi     = {10.1016/j.neuron.2022.03.004},
  pmid    = {35298921},
  url     = {https://doi.org/10.1016/j.neuron.2022.03.004}
}

@article{deane2008-19033669,
  author  = {Deane, R. and Sagare, A. and Hamm, K. and Parisi, M. and Lane, S. and Finn, M. B. and Holtzman, D. M. and Zlokovic, B. V.},
  title   = {{apoE isoform-specific disruption of amyloid beta peptide clearance from mouse brain}},
  journal = {The Journal of clinical investigation},
  year    = {2008},
  doi     = {10.1172/jci36663},
  pmid    = {19033669},
  url     = {https://doi.org/10.1172/jci36663}
}

@article{jain2023-36219197,
  author  = {Jain, N. and Lewis, C. A. and Ulrich, J. D. and Holtzman, D. M.},
  title   = {{Chronic TREM2 activation exacerbates Aβ-associated tau seeding and spreading}},
  journal = {The Journal of experimental medicine},
  year    = {2023},
  doi     = {10.1084/jem.20220654},
  pmid    = {36219197},
  url     = {https://doi.org/10.1084/jem.20220654}
}

@article{shi2018-30140051,
  author  = {Shi, Y. and Holtzman, D. M.},
  title   = {{Interplay between innate immunity and Alzheimer disease: APOE and TREM2 in the spotlight}},
  journal = {Nature reviews. Immunology},
  year    = {2018},
  doi     = {10.1038/s41577-018-0051-1},
  pmid    = {30140051},
  url     = {https://doi.org/10.1038/s41577-018-0051-1}
}

@article{gratuze2018-30572908,
  author  = {Gratuze, M. and Leyns, C. E. G. and Holtzman, D. M.},
  title   = {{New insights into the role of TREM2 in Alzheimer's disease}},
  journal = {Molecular neurodegeneration},
  year    = {2018},
  doi     = {10.1186/s13024-018-0298-9},
  pmid    = {30572908},
  url     = {https://doi.org/10.1186/s13024-018-0298-9}
}

@article{ulrich2017-28426958,
  author  = {Ulrich, J. D. and Ulland, T. K. and Colonna, M. and Holtzman, D. M.},
  title   = {{Elucidating the Role of TREM2 in Alzheimer's Disease}},
  journal = {Neuron},
  year    = {2017},
  doi     = {10.1016/j.neuron.2017.02.042},
  pmid    = {28426958},
  url     = {https://doi.org/10.1016/j.neuron.2017.02.042}
}

@article{chen2021-33176118,
  author  = {Chen, Y. and Strickland, M. R. and Soranno, A. and Holtzman, D. M.},
  title   = {{Apolipoprotein E: Structural Insights and Links to Alzheimer Disease Pathogenesis}},
  journal = {Neuron},
  year    = {2021},
  doi     = {10.1016/j.neuron.2020.10.008},
  pmid    = {33176118},
  url     = {https://doi.org/10.1016/j.neuron.2020.10.008}
}

@article{mahan2022-35109920,
  author  = {Mahan, T. E. and Wang, C. and Bao, X. and Choudhury, A. and Ulrich, J. D. and Holtzman, D. M.},
  title   = {{Selective reduction of astrocyte apoE3 and apoE4 strongly reduces Aβ accumulation and plaque-related pathology in a mouse model of amyloidosis}},
  journal = {Molecular neurodegeneration},
  year    = {2022},
  doi     = {10.1186/s13024-022-00516-0},
  pmid    = {35109920},
  url     = {https://doi.org/10.1186/s13024-022-00516-0}
}

@article{holtzman2012-22393530,
  author  = {Holtzman, D. M. and Herz, J. and Bu, G.},
  title   = {{Apolipoprotein E and apolipoprotein E receptors: normal biology and roles in Alzheimer disease}},
  journal = {Cold Spring Harbor perspectives in medicine},
  year    = {2012},
  doi     = {10.1101/cshperspect.a006312},
  pmid    = {22393530},
  url     = {https://doi.org/10.1101/cshperspect.a006312}
}

@article{wahrle2005-16207708,
  author  = {Wahrle, S. E. and Jiang, H. and Parsadanian, M. and Hartman, R. E. and Bales, K. R. and Paul, S. M. and Holtzman, D. M.},
  title   = {{Deletion of Abca1 increases Abeta deposition in the PDAPP transgenic mouse model of Alzheimer disease}},
  journal = {The Journal of biological chemistry},
  year    = {2005},
  doi     = {10.1074/jbc.m508780200},
  pmid    = {16207708},
  url     = {https://doi.org/10.1074/jbc.m508780200}
}

@article{basak2012-22383525,
  author  = {Basak, J. M. and Verghese, P. B. and Yoon, H. and Kim, J. and Holtzman, D. M.},
  title   = {{Low-density lipoprotein receptor represents an apolipoprotein E-independent pathway of Aβ uptake and degradation by astrocytes}},
  journal = {The Journal of biological chemistry},
  year    = {2012},
  doi     = {10.1074/jbc.m111.288746},
  pmid    = {22383525},
  url     = {https://doi.org/10.1074/jbc.m111.288746}
}

@article{holtzman1995-7568158,
  author  = {Holtzman, D. M. and Pitas, R. E. and Kilbridge, J. and Nathan, B. and Mahley, R. W. and Bu, G. and Schwartz, A. L.},
  title   = {{Low density lipoprotein receptor-related protein mediates apolipoprotein E-dependent neurite outgrowth in a central nervous system-derived neuronal cell line}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {1995},
  doi     = {10.1073/pnas.92.21.9480},
  pmid    = {7568158},
  url     = {https://doi.org/10.1073/pnas.92.21.9480}
}

@article{kang2018-29040522,
  author  = {Kang, S. S. and Kurti, A. and Baker, K. E. and Liu, C. C. and Colonna, M. and Ulrich, J. D. and Holtzman, D. M. and Bu, G. and others},
  title   = {{Behavioral and transcriptomic analysis of Trem2-null mice: not all knockout mice are created equal}},
  journal = {Human molecular genetics},
  year    = {2018},
  doi     = {10.1093/hmg/ddx366},
  pmid    = {29040522},
  url     = {https://doi.org/10.1093/hmg/ddx366}
}

@article{noh2026-42676462,
  author  = {Noh, M. Y. and Sung, W. and Kim, H. and Son, B. and Kim, Y. E. and Choi, Y. Y. and Holtzman, D. M. and Kim, S. H.},
  title   = {{Lecanemab in symptomatic PSEN1 p.Met233Val early-onset Alzheimer's disease: Neuroimaging safety, regional amyloid-PET dynamics, and longitudinal plasma biomarkers}},
  journal = {Alzheimer's \& dementia (Amsterdam, Netherlands)},
  year    = {2026},
  doi     = {10.1002/dad2.70468},
  pmid    = {42676462},
  url     = {https://doi.org/10.1002/dad2.70468}
}

@article{zerbinatti2006-17012232,
  author  = {Zerbinatti, C. V. and Wahrle, S. E. and Kim, H. and Cam, J. A. and Bales, K. and Paul, S. M. and Holtzman, D. M. and Bu, G.},
  title   = {{Apolipoprotein E and low density lipoprotein receptor-related protein facilitate intraneuronal Abeta42 accumulation in amyloid model mice}},
  journal = {The Journal of biological chemistry},
  year    = {2006},
  doi     = {10.1074/jbc.m604436200},
  pmid    = {17012232},
  url     = {https://doi.org/10.1074/jbc.m604436200}
}

@article{ulrich2016-26854967,
  author  = {Ulrich, J. D. and Holtzman, D. M.},
  title   = {{TREM2 Function in Alzheimer's Disease and Neurodegeneration}},
  journal = {ACS chemical neuroscience},
  year    = {2016},
  doi     = {10.1021/acschemneuro.5b00313},
  pmid    = {26854967},
  url     = {https://doi.org/10.1021/acschemneuro.5b00313}
}

@article{bales2002-14993413,
  author  = {Bales, K. R. and Dodart, J. C. and DeMattos, R. B. and Holtzman, D. M. and Paul, S. M.},
  title   = {{Apolipoprotein E, amyloid, and Alzheimer disease}},
  journal = {Molecular interventions},
  year    = {2002},
  doi     = {10.1124/mi.2.6.363},
  pmid    = {14993413},
  url     = {https://doi.org/10.1124/mi.2.6.363}
}

@article{gallardo2019-32096039,
  author  = {Gallardo, G. and Holtzman, D. M.},
  title   = {{Amyloid-β and Tau at the Crossroads of Alzheimer's Disease}},
  journal = {Advances in experimental medicine and biology},
  year    = {2019},
  doi     = {10.1007/978-981-32-9358-8_16},
  pmid    = {32096039},
  url     = {https://doi.org/10.1007/978-981-32-9358-8_16}
}

@article{sun1998-9547235,
  author  = {Sun, Y. and Wu, S. and Bu, G. and Onifade, M. K. and Patel, S. N. and LaDu, M. J. and Fagan, A. M. and Holtzman, D. M.},
  title   = {{Glial fibrillary acidic protein-apolipoprotein E (apoE) transgenic mice: astrocyte-specific expression and differing biological effects of astrocyte-secreted apoE3 and apoE4 lipoproteins}},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year    = {1998},
  doi     = {10.1523/jneurosci.18-09-03261.1998},
  pmid    = {9547235},
  url     = {https://doi.org/10.1523/jneurosci.18-09-03261.1998}
}

@article{shibata2000-11120756,
  author  = {Shibata, M. and Yamada, S. and Kumar, SR. and Calero, M. and Bading, J. and Frangione, B. and Holtzman, D. M. and Miller, C. A. and others},
  title   = {{Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier}},
  journal = {The Journal of clinical investigation},
  year    = {2000},
  doi     = {10.1172/jci10498},
  pmid    = {11120756},
  url     = {https://doi.org/10.1172/jci10498}
}

@article{bell2007-17077814,
  author  = {Bell, R. D. and Sagare, A. P. and Friedman, A. E. and Bedi, G. S. and Holtzman, D. M. and Deane, R. and Zlokovic, B. V.},
  title   = {{Transport pathways for clearance of human Alzheimer's amyloid beta-peptide and apolipoproteins E and J in the mouse central nervous system}},
  journal = {Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism},
  year    = {2007},
  doi     = {10.1038/sj.jcbfm.9600419},
  pmid    = {17077814},
  url     = {https://doi.org/10.1038/sj.jcbfm.9600419}
}