% alzhub.org library filter
% Source: https://alzhub.org/research?about=digital-tools
% 500 entries, in the order the page lists them. Built from alzhub.org's own records.
% 0 entries have no readable author in the source record and carry no author field.

@article{verghese2021-34522910,
  author  = {Verghese, Joe and Mahoney, Jeannette R and Ayers, Emmeline and Ambrose, Anne and Wang, Cuiling and Holtzer, Roee},
  title   = {{Computerised cognitive remediation to enhance mobility in older adults: a single-blind, single-centre, randomised trial}},
  journal = {The lancet. Healthy longevity},
  year    = {2021},
  doi     = {10.1016/s2666-7568(21)00173-2},
  pmid    = {34522910},
  url     = {https://doi.org/10.1016/s2666-7568(21)00173-2}
}

@article{chan2024-38172429,
  author  = {Chan, A. T. C. and Ip, R. T. F. and Tran, J. Y. S. and Chan, J. Y. C. and Tsoi, K. K. F.},
  title   = {{Computerized cognitive training for memory functions in mild cognitive impairment or dementia: a systematic review and meta-analysis}},
  journal = {NPJ digital medicine},
  year    = {2024},
  doi     = {10.1038/s41746-023-00987-5},
  pmid    = {38172429},
  url     = {https://doi.org/10.1038/s41746-023-00987-5}
}

@article{lin2025-40505259,
  author  = {Lin, Xin and Xu, Guangyi and Zhao, Mengjiao and Jiang, Yunxia},
  title   = {{Efficacy of different digital interventions in patients with mild cognitive impairment or dementia: A systematic review and network meta-analysis}},
  journal = {International journal of nursing studies},
  year    = {2025},
  doi     = {10.1016/j.ijnurstu.2025.105129},
  pmid    = {40505259},
  url     = {https://doi.org/10.1016/j.ijnurstu.2025.105129}
}

@article{adedeji2025-41144595,
  author  = {Adedeji, Abiodun and Dogan, Huseyin and Adedoyin, Festus and Heward, Michelle},
  title   = {{Adoption of Telemedicine for Dementia Care in Nigeria: Scoping Review}},
  journal = {Interactive journal of medical research},
  year    = {2025},
  doi     = {10.2196/75168},
  pmid    = {41144595},
  url     = {https://doi.org/10.2196/75168}
}

@article{rodriguez2023-37706540,
  author  = {Rodriguez, Miriam Jocelyn and Kercher, Vanessa Martinez and Jordan, Evan J and Savoy, April and Hill, Jordan R and Werner, Nicole and Owora, Arthur and Castelluccio, Pete and others},
  title   = {{Technology caregiver intervention for Alzheimer's disease (I-CARE): Feasibility and preliminary efficacy of Brain CareNotes}},
  journal = {Journal of the American Geriatrics Society},
  year    = {2023},
  doi     = {10.1111/jgs.18591},
  pmid    = {37706540},
  url     = {https://doi.org/10.1111/jgs.18591}
}

@article{gates2020-32104914,
  author  = {Gates, N. J. and Rutjes, A. W. and Di Nisio, M. and Karim, S. and Chong, L. Y. and March, E. and Martínez, G. and Vernooij, R. W.},
  title   = {{Computerised cognitive training for 12 or more weeks for maintaining cognitive function in cognitively healthy people in late life}},
  journal = {The Cochrane database of systematic reviews},
  year    = {2020},
  doi     = {10.1002/14651858.cd012277.pub3},
  pmid    = {32104914},
  url     = {https://doi.org/10.1002/14651858.cd012277.pub3}
}

@article{gates2019-30864187,
  author  = {Gates, N. J. and Rutjes, A. W. and Di Nisio, M. and Karim, S. and Chong, L. Y. and March, E. and Martínez, G. and Vernooij, R. W.},
  title   = {{Computerised cognitive training for maintaining cognitive function in cognitively healthy people in late life}},
  journal = {The Cochrane database of systematic reviews},
  year    = {2019},
  doi     = {10.1002/14651858.cd012277.pub2},
  pmid    = {30864187},
  url     = {https://doi.org/10.1002/14651858.cd012277.pub2}
}

@article{gates2019-30864746,
  author  = {Gates, N. J. and Rutjes, A. W. and Di Nisio, M. and Karim, S. and Chong, L. Y. and March, E. and Martínez, G. and Vernooij, R. W.},
  title   = {{Computerised cognitive training for maintaining cognitive function in cognitively healthy people in midlife}},
  journal = {The Cochrane database of systematic reviews},
  year    = {2019},
  doi     = {10.1002/14651858.cd012278.pub2},
  pmid    = {30864746},
  url     = {https://doi.org/10.1002/14651858.cd012278.pub2}
}

@article{zhang2019-31427316,
  author  = {Zhang, H. and Huntley, J. and Bhome, R. and Holmes, B. and Cahill, J. and Gould, R. L. and Wang, H. and Yu, X. and others},
  title   = {{Effect of computerised cognitive training on cognitive outcomes in mild cognitive impairment: a systematic review and meta-analysis}},
  journal = {BMJ open},
  year    = {2019},
  doi     = {10.1136/bmjopen-2018-027062},
  pmid    = {31427316},
  url     = {https://doi.org/10.1136/bmjopen-2018-027062}
}

@article{leonsalas2023-36256522,
  author  = {León-Salas, B. and González-Hernández, Y. and Infante-Ventura, D. and de Armas-Castellano, A. and García-García, J. and García-Hernández, M. and Carmona-Rodríguez, M. and Olazarán, J. and others},
  title   = {{Telemedicine for neurological diseases: A systematic review and meta-analysis}},
  journal = {European journal of neurology},
  year    = {2023},
  doi     = {10.1111/ene.15599},
  pmid    = {36256522},
  url     = {https://doi.org/10.1111/ene.15599}
}

@article{oliveira2021-34065698,
  author  = {Oliveira, Jorge and Gamito, Pedro and Souto, Teresa and Conde, Rita and Ferreira, Maria and Corotnean, Tatiana and Fernandes, Adriano and Silva, Henrique and others},
  title   = {{Virtual Reality-Based Cognitive Stimulation on People with Mild to Moderate Dementia due to Alzheimer's Disease: A Pilot Randomized Controlled Trial}},
  journal = {International journal of environmental research and public health},
  year    = {2021},
  doi     = {10.3390/ijerph18105290},
  pmid    = {34065698},
  url     = {https://doi.org/10.3390/ijerph18105290}
}

@article{shyu2022-34036705,
  author  = {Shyu, Yea-Ing L and Lin, Chung-Chih and Kwok, Yam-Ting and Shyu, Hann-Yeh and Kuo, Li-Min},
  title   = {{A community-based computerised cognitive training program for older persons with mild dementia: A pilot study}},
  journal = {Australasian journal on ageing},
  year    = {2022},
  doi     = {10.1111/ajag.12962},
  pmid    = {34036705},
  url     = {https://doi.org/10.1111/ajag.12962}
}

@article{ma2023-38298930,
  author  = {Ma, Suk Ling and Tang, Katsie Tung and Lau, Niki Cheuk Ting and Chiu, Clement Lek Hin and Lin, Cuichan and Lam, Linda Chiu Wa and Lee, Allen Ting Chun},
  title   = {{Effect of computerized cognitive training on mood, cognition, and serum brain-derived neurotrophic factor level in late-life depression - a pilot randomized controlled trial}},
  journal = {Frontiers in psychiatry},
  year    = {2023},
  doi     = {10.3389/fpsyt.2023.1287822},
  pmid    = {38298930},
  url     = {https://doi.org/10.3389/fpsyt.2023.1287822}
}

@article{elsappagh2021-33514817,
  author  = {El-Sappagh, S. and Alonso, J. M. and Islam, S. M. R. and Sultan, A. M. and Kwak, K. S.},
  title   = {{A multilayer multimodal detection and prediction model based on explainable artificial intelligence for Alzheimer's disease}},
  journal = {Scientific reports},
  year    = {2021},
  doi     = {10.1038/s41598-021-82098-3},
  pmid    = {33514817},
  url     = {https://doi.org/10.1038/s41598-021-82098-3}
}

@article{gavelin2022-35714854,
  author  = {Gavelin, H. M. and Domellöf, M. E. and Leung, I. and Neely, A. S. and Launder, N. H. and Nategh, L. and Finke, C. and Lampit, A.},
  title   = {{Computerized cognitive training in Parkinson's disease: A systematic review and meta-analysis}},
  journal = {Ageing research reviews},
  year    = {2022},
  doi     = {10.1016/j.arr.2022.101671},
  pmid    = {35714854},
  url     = {https://doi.org/10.1016/j.arr.2022.101671}
}

@article{robert2020-32159519,
  author  = {Robert, P. and Manera, V. and Derreumaux, A. and Ferrandez Y Montesino, M. and Leone, E. and Fabre, R. and Bourgeois, J.},
  title   = {{Efficacy of a Web App for Cognitive Training (MeMo) Regarding Cognitive and Behavioral Performance in People With Neurocognitive Disorders: Randomized Controlled Trial}},
  journal = {Journal of medical Internet research},
  year    = {2020},
  doi     = {10.2196/17167},
  pmid    = {32159519},
  url     = {https://doi.org/10.2196/17167}
}

@article{staffaroni2024-38558141,
  author  = {Staffaroni, A. M. and Clark, A. L. and Taylor, J. C. and Heuer, H. W. and Sanderson-Cimino, M. and Wise, A. B. and Dhanam, S. and Cobigo, Y. and others},
  title   = {{Reliability and Validity of Smartphone Cognitive Testing for Frontotemporal Lobar Degeneration}},
  journal = {JAMA network open},
  year    = {2024},
  doi     = {10.1001/jamanetworkopen.2024.4266},
  pmid    = {38558141},
  url     = {https://doi.org/10.1001/jamanetworkopen.2024.4266}
}

@article{yaxley2016-27474375,
  author  = {Yaxley, J. W. and Coughlin, G. D. and Chambers, S. K. and Occhipinti, S. and Samaratunga, H. and Zajdlewicz, L. and Dunglison, N. and Carter, R. and others},
  title   = {{Robot-assisted laparoscopic prostatectomy versus open radical retropubic prostatectomy: early outcomes from a randomised controlled phase 3 study}},
  journal = {Lancet (London, England)},
  year    = {2016},
  doi     = {10.1016/s0140-6736(16)30592-x},
  pmid    = {27474375},
  url     = {https://doi.org/10.1016/s0140-6736(16)30592-x}
}

@article{triana2020-32429770,
  author  = {Triana, Austin J. and Gusdorf, Roman E and Shah, Kaustav P. and Horst, Sara},
  title   = {{Technology Literacy as a Barrier to Telehealth During COVID-19}},
  journal = {Telemedicine Journal and e-Health},
  year    = {2020},
  doi     = {10.1089/tmj.2020.0155},
  pmid    = {32429770},
  url     = {https://doi.org/10.1089/tmj.2020.0155}
}

@article{lampit2019-31328637,
  author  = {Lampit, A. and Heine, J. and Finke, C. and Barnett, M. H. and Valenzuela, M. and Wolf, A. and Leung, I. H. K. and Hill, N. T. M.},
  title   = {{Computerized Cognitive Training in Multiple Sclerosis: A Systematic Review and Meta-analysis}},
  journal = {Neurorehabilitation and neural repair},
  year    = {2019},
  doi     = {10.1177/1545968319860490},
  pmid    = {31328637},
  url     = {https://doi.org/10.1177/1545968319860490}
}

@article{tenbrinke2018-29378515,
  author  = {Ten Brinke, L. F. and Best, JR. and Crockett, R. A. and Liu-Ambrose, T.},
  title   = {{The effects of an 8-week computerized cognitive training program in older adults: a study protocol for a randomized controlled trial}},
  journal = {BMC geriatrics},
  year    = {2018},
  doi     = {10.1186/s12877-018-0730-6},
  pmid    = {29378515},
  url     = {https://doi.org/10.1186/s12877-018-0730-6}
}

@article{weiner2023-36209495,
  author  = {Weiner, M. W. and Veitch, D. P. and Miller, M. J. and Aisen, P. S. and Albala, B. and Beckett, L. A. and Green, R. C. and Harvey, D. and others},
  title   = {{Increasing participant diversity in AD research: Plans for digital screening, blood testing, and a community-engaged approach in the Alzheimer's Disease Neuroimaging Initiative 4}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2023},
  doi     = {10.1002/alz.12797},
  pmid    = {36209495},
  url     = {https://doi.org/10.1002/alz.12797}
}

@article{meltzer2023-34694201,
  author  = {Meltzer, J. A. and Kates Rose, M. and Le, A. Y. and Spencer, K. A. and Goldstein, L. and Gubanova, A. and Lai, A. C. and Yossofzai, M. and others},
  title   = {{Improvement in executive function for older adults through smartphone apps: a randomized clinical trial comparing language learning and brain training}},
  journal = {Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition},
  year    = {2023},
  doi     = {10.1080/13825585.2021.1991262},
  pmid    = {34694201},
  url     = {https://doi.org/10.1080/13825585.2021.1991262}
}

@article{kim2026-41913058,
  author  = {Kim, Hairin and Soberanes, Daniel and Jutten, Roos J and Dubbelman, Mark A and Yang, Hyun-Sik and Marshall, Gad A and Johnson, Keith A and Betensky, Rebecca A and others},
  title   = {{Combining p-tau217 and digital cognitive testing to predict cognitive decline}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2026},
  doi     = {10.1002/alz.71328},
  pmid    = {41913058},
  url     = {https://doi.org/10.1002/alz.71328}
}

@article{baharfuchs2017-28922158,
  author  = {Bahar-Fuchs, A. and Webb, S. and Bartsch, L. and Clare, L. and Rebok, G. and Cherbuin, N. and Anstey, K. J.},
  title   = {{Tailored and Adaptive Computerized Cognitive Training in Older Adults at Risk for Dementia: A Randomized Controlled Trial}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2017},
  doi     = {10.3233/jad-170404},
  pmid    = {28922158},
  url     = {https://doi.org/10.3233/jad-170404}
}

@article{barban2016-26205305,
  author  = {Barban, F. and Annicchiarico, R. and Pantelopoulos, S. and Federici, A. and Perri, R. and Fadda, L. and Carlesimo, G. A. and Ricci, C. and others},
  title   = {{Protecting cognition from aging and Alzheimer's disease: a computerized cognitive training combined with reminiscence therapy}},
  journal = {International journal of geriatric psychiatry},
  year    = {2016},
  doi     = {10.1002/gps.4328},
  pmid    = {26205305},
  url     = {https://doi.org/10.1002/gps.4328}
}

@article{jo2019-31481890,
  author  = {Jo, T. and Nho, K. and Saykin, A. J.},
  title   = {{Deep Learning in Alzheimer's Disease: Diagnostic Classification and Prognostic Prediction Using Neuroimaging Data}},
  journal = {Frontiers in aging neuroscience},
  year    = {2019},
  doi     = {10.3389/fnagi.2019.00220},
  pmid    = {31481890},
  url     = {https://doi.org/10.3389/fnagi.2019.00220}
}

@article{vimbi2024-38578524,
  author  = {Vimbi, V. and Shaffi, N. and Mahmud, M.},
  title   = {{Interpreting artificial intelligence models: a systematic review on the application of LIME and SHAP in Alzheimer's disease detection}},
  journal = {Brain informatics},
  year    = {2024},
  doi     = {10.1186/s40708-024-00222-1},
  pmid    = {38578524},
  url     = {https://doi.org/10.1186/s40708-024-00222-1}
}

@article{sun2026-41854616,
  author  = {Sun, Haoqi and Milton, Sasha and Fang, Yi and Taha, Hash Brown and Shiju, Shreya and Thomas, Robert J and Ganglberger, Wolfgang and Pase, Matthew P and others},
  title   = {{Machine Learning-Based Sleep Electroencephalographic Brain Age Index and Dementia Risk: An Individual Participant Data Meta-Analysis}},
  journal = {JAMA network open},
  year    = {2026},
  doi     = {10.1001/jamanetworkopen.2026.1521},
  pmid    = {41854616},
  url     = {https://doi.org/10.1001/jamanetworkopen.2026.1521}
}

@article{xue2024-38965435,
  author  = {Xue, C. and Kowshik, S. S. and Lteif, D. and Puducheri, S. and Jasodanand, V. H. and Zhou, O. T. and Walia, A. S. and Guney, O. B. and others},
  title   = {{AI-based differential diagnosis of dementia etiologies on multimodal data}},
  journal = {Nature medicine},
  year    = {2024},
  doi     = {10.1038/s41591-024-03118-z},
  pmid    = {38965435},
  url     = {https://doi.org/10.1038/s41591-024-03118-z}
}

@article{borchert2023-37563912,
  author  = {Borchert, R. J. and Azevedo, T. and Badhwar, A. and Bernal, J. and Betts, M. and Bruffaerts, R. and Burkhart, M. C. and Dewachter, I. and others},
  title   = {{Artificial intelligence for diagnostic and prognostic neuroimaging in dementia: A systematic review}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2023},
  doi     = {10.1002/alz.13412},
  pmid    = {37563912},
  url     = {https://doi.org/10.1002/alz.13412}
}

@article{gates2019-30864747,
  author  = {Gates, N. J. and Vernooij, R. W. and Di Nisio, M. and Karim, S. and March, E. and Martínez, G. and Rutjes, A. W.},
  title   = {{Computerised cognitive training for preventing dementia in people with mild cognitive impairment}},
  journal = {The Cochrane database of systematic reviews},
  year    = {2019},
  doi     = {10.1002/14651858.cd012279.pub2},
  pmid    = {30864747},
  url     = {https://doi.org/10.1002/14651858.cd012279.pub2}
}

@article{coyle2015-24998488,
  author  = {Coyle, H. and Traynor, V. and Solowij, N.},
  title   = {{Computerized and virtual reality cognitive training for individuals at high risk of cognitive decline: systematic review of the literature}},
  journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry},
  year    = {2015},
  doi     = {10.1016/j.jagp.2014.04.009},
  pmid    = {24998488},
  url     = {https://doi.org/10.1016/j.jagp.2014.04.009}
}

@article{kang2021-33955835,
  author  = {Kang, J. M. and Kim, N. and Lee, S. Y. and Woo, S. K. and Park, G. and Yeon, B. K. and Park, J. W. and Youn, J. H. and others},
  title   = {{Effect of Cognitive Training in Fully Immersive Virtual Reality on Visuospatial Function and Frontal-Occipital Functional Connectivity in Predementia: Randomized Controlled Trial}},
  journal = {Journal of medical Internet research},
  year    = {2021},
  doi     = {10.2196/24526},
  pmid    = {33955835},
  url     = {https://doi.org/10.2196/24526}
}

@article{contrerassomoza2021-33967901,
  author  = {Contreras-Somoza, L. M. and Irazoki, E. and Toribio-Guzmán, J. M. and de la Torre-Díez, I. and Diaz-Baquero, A. A. and Parra-Vidales, E. and Perea-Bartolomé, M. V. and MÁ, Franco-Martín},
  title   = {{Usability and User Experience of Cognitive Intervention Technologies for Elderly People With MCI or Dementia: A Systematic Review}},
  journal = {Frontiers in psychology},
  year    = {2021},
  doi     = {10.3389/fpsyg.2021.636116},
  pmid    = {33967901},
  url     = {https://doi.org/10.3389/fpsyg.2021.636116}
}

@article{hassandra2021-33759797,
  author  = {Hassandra, M. and Galanis, E. and Hatzigeorgiadis, A. and Goudas, M. and Mouzakidis, C. and Karathanasi, E. M. and Petridou, N. and Tsolaki, M. and others},
  title   = {{Α Virtual Reality App for Physical and Cognitive Training of Older People With Mild Cognitive Impairment: Mixed Methods Feasibility Study}},
  journal = {JMIR serious games},
  year    = {2021},
  doi     = {10.2196/24170},
  pmid    = {33759797},
  url     = {https://doi.org/10.2196/24170}
}

@article{chae2023-36468299,
  author  = {Chae, H. J. and Lee, S. H.},
  title   = {{Effectiveness of online-based cognitive intervention in community-dwelling older adults with cognitive dysfunction: A systematic review and meta-analysis}},
  journal = {International journal of geriatric psychiatry},
  year    = {2023},
  doi     = {10.1002/gps.5853},
  pmid    = {36468299},
  url     = {https://doi.org/10.1002/gps.5853}
}

@article{wang2019-31298717,
  author  = {Wang, L. and Sha, L. and Lakin, JR. and Bynum, J. and Bates, D. W. and Hong, P. and Zhou, L.},
  title   = {{Development and Validation of a Deep Learning Algorithm for Mortality Prediction in Selecting Patients With Dementia for Earlier Palliative Care Interventions}},
  journal = {JAMA network open},
  year    = {2019},
  doi     = {10.1001/jamanetworkopen.2019.6972},
  pmid    = {31298717},
  url     = {https://doi.org/10.1001/jamanetworkopen.2019.6972}
}

@article{chan2018-29921507,
  author  = {Chan, J. Y. C. and Kwong, J. S. W. and Wong, A. and Kwok, T. C. Y. and Tsoi, K. K. F.},
  title   = {{Comparison of Computerized and Paper-and-Pencil Memory Tests in Detection of Mild Cognitive Impairment and Dementia: A Systematic Review and Meta-analysis of Diagnostic Studies}},
  journal = {Journal of the American Medical Directors Association},
  year    = {2018},
  doi     = {10.1016/j.jamda.2018.05.010},
  pmid    = {29921507},
  url     = {https://doi.org/10.1016/j.jamda.2018.05.010}
}

@article{walker1996-9038610,
  author  = {Walker, L. G. and Wesnes, K. P. and Heys, S. D. and Walker, M. B. and Lolley, J. and Eremin, O.},
  title   = {{The cognitive effects of recombinant interleukin-2 (rIL-2) therapy: a controlled clinical trial using computerised assessments}},
  journal = {European journal of cancer (Oxford, England : 1990)},
  year    = {1996},
  doi     = {10.1016/s0959-8049(96)00300-0},
  pmid    = {9038610},
  url     = {https://doi.org/10.1016/s0959-8049(96)00300-0}
}

@article{liu2024-39147783,
  author  = {Liu, L. and Wang, H. and Xing, Y. and Zhang, Z. and Zhang, Q. and Dong, M. and Ma, Z. and Cai, L. and others},
  title   = {{Dose-response relationship between computerized cognitive training and cognitive improvement}},
  journal = {NPJ digital medicine},
  year    = {2024},
  doi     = {10.1038/s41746-024-01210-9},
  pmid    = {39147783},
  url     = {https://doi.org/10.1038/s41746-024-01210-9}
}

@article{cavallo2019-29295652,
  author  = {Cavallo, M. and Angilletta, C.},
  title   = {{Long-Lasting Neuropsychological Effects of a Computerized Cognitive Training in Patients Affected by Early Stage Alzheimer's Disease: Are They Stable Over Time?}},
  journal = {Journal of applied gerontology : the official journal of the Southern Gerontological Society},
  year    = {2019},
  doi     = {10.1177/0733464817750276},
  pmid    = {29295652},
  url     = {https://doi.org/10.1177/0733464817750276}
}

@article{leung2022-35675967,
  author  = {Leung, C. and Wong, K. C. and So, W. W. Y. and Tse, Z. C. K. and Li, D. and Cao, Y. and Shum, D. H. K.},
  title   = {{The application of technology to improve cognition in older adults: A review and suggestions for future directions}},
  journal = {PsyCh journal},
  year    = {2022},
  doi     = {10.1002/pchj.565},
  pmid    = {35675967},
  url     = {https://doi.org/10.1002/pchj.565}
}

@article{chang2021-33803217,
  author  = {Chang, C. H. and Lin, C. H. and Lane, H. Y.},
  title   = {{Machine Learning and Novel Biomarkers for the Diagnosis of Alzheimer's Disease}},
  journal = {International journal of molecular sciences},
  year    = {2021},
  doi     = {10.3390/ijms22052761},
  pmid    = {33803217},
  url     = {https://doi.org/10.3390/ijms22052761}
}

@article{sunderaraman2024-38226510,
  author  = {Sunderaraman, Preeti and De Anda-Duran, Ileana and Karjadi, Cody and Peterson, Julia and Ding, Huitong and Devine, Sherral A and Shih, Ludy C and Popp, Zachary and others},
  title   = {{Design and Feasibility Analysis of a Smartphone-Based Digital Cognitive Assessment Study in the Framingham Heart Study}},
  journal = {Journal of the American Heart Association},
  year    = {2024},
  doi     = {10.1161/jaha.123.031348},
  pmid    = {38226510},
  url     = {https://doi.org/10.1161/jaha.123.031348}
}

@article{ansart2021-33091740,
  author  = {Ansart, M. and Epelbaum, S. and Bassignana, G. and Bône, A. and Bottani, S. and Cattai, T. and Couronné, R. and Faouzi, J. and others},
  title   = {{Predicting the progression of mild cognitive impairment using machine learning: A systematic, quantitative and critical review}},
  journal = {Medical image analysis},
  year    = {2021},
  doi     = {10.1016/j.media.2020.101848},
  pmid    = {33091740},
  url     = {https://doi.org/10.1016/j.media.2020.101848}
}

@article{polk2026-42270927,
  author  = {Polk, Sarah E and Clark, Lindsay R and Basche, Kristin and Kleineidam, Luca and Glanz, Wenzel and Butryn, Michaela and Perneczky, Robert and Buerger, Katharina and others},
  title   = {{Smartphone-based detection of subtle memory decline in prodromal Alzheimer's disease}},
  journal = {NPJ digital medicine},
  year    = {2026},
  doi     = {10.1038/s41746-026-02731-1},
  pmid    = {42270927},
  url     = {https://doi.org/10.1038/s41746-026-02731-1}
}

@article{paolillo2024-38922667,
  author  = {Paolillo, Emily W and Casaletto, Kaitlin B and Clark, Annie L and Taylor, Jack C and Heuer, Hilary W and Wise, Amy B and Dhanam, Sreya and Sanderson-Cimino, Mark and others},
  title   = {{Examining Associations Between Smartphone Use and Clinical Severity in Frontotemporal Dementia: Proof-of-Concept Study}},
  journal = {JMIR aging},
  year    = {2024},
  doi     = {10.2196/52831},
  pmid    = {38922667},
  url     = {https://doi.org/10.2196/52831}
}

@article{wong2025-40324167,
  author  = {Wong, Duo Wai‐Chi and Wang, Jiao and Cheung, Sophia Ming-Yan and Lai, Derek Ka-Hei and Chiu, Armstrong Tat San and Pu, Dai and Cheung, James Chung‐Wai and Kwok, Timothy C. Y.},
  title   = {{Current Technological Advances in Dysphagia Screening: Systematic Scoping Review}},
  journal = {Journal of Medical Internet Research},
  year    = {2025},
  doi     = {10.2196/65551},
  pmid    = {40324167},
  url     = {https://doi.org/10.2196/65551}
}

@article{ge2018-30219036,
  author  = {Ge, S. and Zhu, Z. and Wu, B. and McConnell, E. S.},
  title   = {{Technology-based cognitive training and rehabilitation interventions for individuals with mild cognitive impairment: a systematic review}},
  journal = {BMC geriatrics},
  year    = {2018},
  doi     = {10.1186/s12877-018-0893-1},
  pmid    = {30219036},
  url     = {https://doi.org/10.1186/s12877-018-0893-1}
}

@article{tenbrinke2017-28693437,
  author  = {Ten Brinke, L. F. and Davis, J. C. and Barha, C. K. and Liu-Ambrose, T.},
  title   = {{Effects of computerized cognitive training on neuroimaging outcomes in older adults: a systematic review}},
  journal = {BMC geriatrics},
  year    = {2017},
  doi     = {10.1186/s12877-017-0529-x},
  pmid    = {28693437},
  url     = {https://doi.org/10.1186/s12877-017-0529-x}
}

@article{clay2020-32280091,
  author  = {Clay, F. and Howett, D. and FitzGerald, J. and Fletcher, P. and Chan, D. and Price, A.},
  title   = {{Use of Immersive Virtual Reality in the Assessment and Treatment of Alzheimer's Disease: A Systematic Review}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2020},
  doi     = {10.3233/jad-191218},
  pmid    = {32280091},
  url     = {https://doi.org/10.3233/jad-191218}
}

@article{li2019-30708349,
  author  = {Li, B. Y. and He, N. Y. and Qiao, Y. and Xu, H. M. and Lu, Y. Z. and Cui, P. J. and Ling, H. W. and Yan, F. H. and others},
  title   = {{Computerized cognitive training for Chinese mild cognitive impairment patients: A neuropsychological and fMRI study}},
  journal = {NeuroImage. Clinical},
  year    = {2019},
  doi     = {10.1016/j.nicl.2019.101691},
  pmid    = {30708349},
  url     = {https://doi.org/10.1016/j.nicl.2019.101691}
}

@article{sayma2020-31600389,
  author  = {Sayma, M. and Tuijt, R. and Cooper, C. and Walters, K.},
  title   = {{Are We There Yet? Immersive Virtual Reality to Improve Cognitive Function in Dementia and Mild Cognitive Impairment}},
  journal = {The Gerontologist},
  year    = {2020},
  doi     = {10.1093/geront/gnz132},
  pmid    = {31600389},
  url     = {https://doi.org/10.1093/geront/gnz132}
}

@article{moyle2013-23506125,
  author  = {Moyle, W. and Cooke, M. and Beattie, E. and Jones, C. and Klein, B. and Cook, G. and Gray, C.},
  title   = {{Exploring the effect of companion robots on emotional expression in older adults with dementia: a pilot randomized controlled trial}},
  journal = {Journal of gerontological nursing},
  year    = {2013},
  doi     = {10.3928/00989134-20130313-03},
  pmid    = {23506125},
  url     = {https://doi.org/10.3928/00989134-20130313-03}
}

@article{tashjian2017-28356241,
  author  = {Tashjian, V. C. and Mosadeghi, S. and Howard, A. R. and Lopez, M. and Dupuy, T. and Reid, M. and Martinez, B. and Ahmed, S. and others},
  title   = {{Virtual Reality for Management of Pain in Hospitalized Patients: Results of a Controlled Trial}},
  journal = {JMIR mental health},
  year    = {2017},
  doi     = {10.2196/mental.7387},
  pmid    = {28356241},
  url     = {https://doi.org/10.2196/mental.7387}
}

@article{hackett2022-32684106,
  author  = {Hackett, K. and Lehman, S. and Divers, R. and Ambrogi, M. and Gomes, L. and Tan, C. C. and Giovannetti, T.},
  title   = {{Remind Me To Remember: A pilot study of a novel smartphone reminder application for older adults with dementia and mild cognitive impairment}},
  journal = {Neuropsychological rehabilitation},
  year    = {2022},
  doi     = {10.1080/09602011.2020.1794909},
  pmid    = {32684106},
  url     = {https://doi.org/10.1080/09602011.2020.1794909}
}

@article{delafuentegarcia2020-33185605,
  author  = {de la Fuente Garcia, S. and Ritchie, C. W. and Luz, S.},
  title   = {{Artificial Intelligence, Speech, and Language Processing Approaches to Monitoring Alzheimer's Disease: A Systematic Review}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2020},
  doi     = {10.3233/jad-200888},
  pmid    = {33185605},
  url     = {https://doi.org/10.3233/jad-200888}
}

@article{yu2022-35462001,
  author  = {Yu, C. and Sommerlad, A. and Sakure, L. and Livingston, G.},
  title   = {{Socially assistive robots for people with dementia: Systematic review and meta-analysis of feasibility, acceptability and the effect on cognition, neuropsychiatric symptoms and quality of life}},
  journal = {Ageing research reviews},
  year    = {2022},
  doi     = {10.1016/j.arr.2022.101633},
  pmid    = {35462001},
  url     = {https://doi.org/10.1016/j.arr.2022.101633}
}

@article{husebo2019-32116687,
  author  = {Husebo, B. S. and Heintz, H. L. and Berge, L. I. and Owoyemi, P. and Rahman, A. T. and Vahia, IV.},
  title   = {{Sensing Technology to Monitor Behavioral and Psychological Symptoms and to Assess Treatment Response in People With Dementia. A Systematic Review}},
  journal = {Frontiers in pharmacology},
  year    = {2019},
  doi     = {10.3389/fphar.2019.01699},
  pmid    = {32116687},
  url     = {https://doi.org/10.3389/fphar.2019.01699}
}

@article{gavelin2020-33234647,
  author  = {Gavelin, Hanna Malmberg and Domellöf, Magdalena and Leung, Isabella and Neely, Anna Stigsdotter and Finke, Carsten and Lampit, Amit},
  title   = {{Computerised cognitive training in Parkinson's disease: a protocol for a systematic review and updated meta-analysis}},
  journal = {BMJ open},
  year    = {2020},
  doi     = {10.1136/bmjopen-2020-040656},
  pmid    = {33234647},
  url     = {https://doi.org/10.1136/bmjopen-2020-040656}
}

@article{wang2017-28284228,
  author  = {Wang, Q. and Markopoulos, P. and Yu, B. and Chen, W. and Timmermans, A.},
  title   = {{Interactive wearable systems for upper body rehabilitation: a systematic review}},
  journal = {Journal of neuroengineering and rehabilitation},
  year    = {2017},
  doi     = {10.1186/s12984-017-0229-y},
  pmid    = {28284228},
  url     = {https://doi.org/10.1186/s12984-017-0229-y}
}

@article{cheung2022-36192349,
  author  = {Cheung, C. Y. and Ran, A. R. and Wang, S. and Chan, V. T. T. and Sham, K. and Hilal, S. and Venketasubramanian, N. and Cheng, C. Y. and others},
  title   = {{A deep learning model for detection of Alzheimer's disease based on retinal photographs: a retrospective, multicentre case-control study}},
  journal = {The Lancet. Digital health},
  year    = {2022},
  doi     = {10.1016/s2589-7500(22)00169-8},
  pmid    = {36192349},
  url     = {https://doi.org/10.1016/s2589-7500(22)00169-8}
}

@article{henschel2020-32526386,
  author  = {Henschel, L. and Conjeti, S. and Estrada, S. and Diers, K. and Fischl, B. and Reuter, M.},
  title   = {{FastSurfer - A fast and accurate deep learning based neuroimaging pipeline}},
  journal = {NeuroImage},
  year    = {2020},
  doi     = {10.1016/j.neuroimage.2020.117012},
  pmid    = {32526386},
  url     = {https://doi.org/10.1016/j.neuroimage.2020.117012}
}

@article{spooner2020-33230128,
  author  = {Spooner, A. and Chen, E. and Sowmya, A. and Sachdev, P. and Kochan, N. A. and Trollor, J. and Brodaty, H.},
  title   = {{A comparison of machine learning methods for survival analysis of high-dimensional clinical data for dementia prediction}},
  journal = {Scientific reports},
  year    = {2020},
  doi     = {10.1038/s41598-020-77220-w},
  pmid    = {33230128},
  url     = {https://doi.org/10.1038/s41598-020-77220-w}
}

@article{piau2019-31471958,
  author  = {Piau, A. and Wild, K. and Mattek, N. and Kaye, J.},
  title   = {{Current State of Digital Biomarker Technologies for Real-Life, Home-Based Monitoring of Cognitive Function for Mild Cognitive Impairment to Mild Alzheimer Disease and Implications for Clinical Care: Systematic Review}},
  journal = {Journal of medical Internet research},
  year    = {2019},
  doi     = {10.2196/12785},
  pmid    = {31471958},
  url     = {https://doi.org/10.2196/12785}
}

@article{vanderroest2017-28602027,
  author  = {Van der Roest, H. G. and Wenborn, J. and Pastink, C. and Dröes, R. M. and Orrell, M.},
  title   = {{Assistive technology for memory support in dementia}},
  journal = {The Cochrane database of systematic reviews},
  year    = {2017},
  doi     = {10.1002/14651858.cd009627.pub2},
  pmid    = {28602027},
  url     = {https://doi.org/10.1002/14651858.cd009627.pub2}
}

@article{thapa2020-32365533,
  author  = {Thapa, N. and Park, H. J. and Yang, J. G. and Son, H. and Jang, M. and Lee, J. and Kang, S. W. and Park, K. W. and others},
  title   = {{The Effect of a Virtual Reality-Based Intervention Program on Cognition in Older Adults with Mild Cognitive Impairment: A Randomized Control Trial}},
  journal = {Journal of clinical medicine},
  year    = {2020},
  doi     = {10.3390/jcm9051283},
  pmid    = {32365533},
  url     = {https://doi.org/10.3390/jcm9051283}
}

@article{abdulazeem2025-39928936,
  author  = {Abdulazeem, Hebatullah Mohamed and Nascimento, Israel Júnior Borges do and Weerasekara, Ishanka and Sharifan, Amin and Bianco, Véronique and Cunningham, Charnay and Kularathne, Indunil and Deeken, Genevieve and others},
  title   = {{Use of Digital Health Technologies for Dementia Care: Bibliometric Analysis and Report}},
  journal = {JMIR Mental Health},
  year    = {2025},
  doi     = {10.2196/64445},
  pmid    = {39928936},
  url     = {https://doi.org/10.2196/64445}
}

@article{papaioannou2022-35811514,
  author  = {Papaioannou, T. and Voinescu, A. and Petrini, K. and Stanton Fraser, D.},
  title   = {{Efficacy and Moderators of Virtual Reality for Cognitive Training in People with Dementia and Mild Cognitive Impairment: A Systematic Review and Meta-Analysis}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2022},
  doi     = {10.3233/jad-210672},
  pmid    = {35811514},
  url     = {https://doi.org/10.3233/jad-210672}
}

@article{kueider2012-22792378,
  author  = {Kueider, A. M. and Parisi, J. M. and Gross, A. L. and Rebok, G. W.},
  title   = {{Computerized cognitive training with older adults: a systematic review}},
  journal = {PloS one},
  year    = {2012},
  doi     = {10.1371/journal.pone.0040588},
  pmid    = {22792378},
  url     = {https://doi.org/10.1371/journal.pone.0040588}
}

@article{wild2008-19012868,
  author  = {Wild, K. and Howieson, D. and Webbe, F. and Seelye, A. and Kaye, J.},
  title   = {{Status of computerized cognitive testing in aging: a systematic review}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2008},
  doi     = {10.1016/j.jalz.2008.07.003},
  pmid    = {19012868},
  url     = {https://doi.org/10.1016/j.jalz.2008.07.003}
}

@article{meier2021-34168269,
  author  = {Meier, I. B. and Buegler, M. and Harms, R. and Seixas, A. and Çöltekin, A. and Tarnanas, I.},
  title   = {{Using a Digital Neuro Signature to measure longitudinal individual-level change in Alzheimer's disease: the Altoida large cohort study}},
  journal = {NPJ digital medicine},
  year    = {2021},
  doi     = {10.1038/s41746-021-00470-z},
  pmid    = {34168269},
  url     = {https://doi.org/10.1038/s41746-021-00470-z}
}

@article{yi2021-33887231,
  author  = {Yi, J. S. and Pittman, C. A. and Price, C. L. and Nieman, C. L. and Oh, E. S.},
  title   = {{Telemedicine and Dementia Care: A Systematic Review of Barriers and Facilitators}},
  journal = {Journal of the American Medical Directors Association},
  year    = {2021},
  doi     = {10.1016/j.jamda.2021.03.015},
  pmid    = {33887231},
  url     = {https://doi.org/10.1016/j.jamda.2021.03.015}
}

@article{martin2023-36735865,
  author  = {Martin, S. A. and Townend, F. J. and Barkhof, F. and Cole, J. H.},
  title   = {{Interpretable machine learning for dementia: A systematic review}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2023},
  doi     = {10.1002/alz.12948},
  pmid    = {36735865},
  url     = {https://doi.org/10.1002/alz.12948}
}

@article{james2021-34913981,
  author  = {James, C. and Ranson, J. M. and Everson, R. and Llewellyn, D. J.},
  title   = {{Performance of Machine Learning Algorithms for Predicting Progression to Dementia in Memory Clinic Patients}},
  journal = {JAMA network open},
  year    = {2021},
  doi     = {10.1001/jamanetworkopen.2021.36553},
  pmid    = {34913981},
  url     = {https://doi.org/10.1001/jamanetworkopen.2021.36553}
}

@article{lee2019-30760848,
  author  = {Lee, G. and Nho, K. and Kang, B. and Sohn, K. A. and Kim, D. and {for Alzheimer’s Disease Neuroimaging Initiative}},
  title   = {{Predicting Alzheimer's disease progression using multi-modal deep learning approach}},
  journal = {Scientific reports},
  year    = {2019},
  doi     = {10.1038/s41598-018-37769-z},
  pmid    = {30760848},
  url     = {https://doi.org/10.1038/s41598-018-37769-z}
}

@article{hill2017-27838936,
  author  = {Hill, N. T. and Mowszowski, L. and Naismith, S. L. and Chadwick, V. L. and Valenzuela, M. and Lampit, A.},
  title   = {{Computerized Cognitive Training in Older Adults With Mild Cognitive Impairment or Dementia: A Systematic Review and Meta-Analysis}},
  journal = {The American journal of psychiatry},
  year    = {2017},
  doi     = {10.1176/appi.ajp.2016.16030360},
  pmid    = {27838936},
  url     = {https://doi.org/10.1176/appi.ajp.2016.16030360}
}

@article{shah2017-28092015,
  author  = {Shah, T. M. and Weinborn, M. and Verdile, G. and Sohrabi, H. R. and Martins, R. N.},
  title   = {{Enhancing Cognitive Functioning in Healthly Older Adults: a Systematic Review of the Clinical Significance of Commercially Available Computerized Cognitive Training in Preventing Cognitive Decline}},
  journal = {Neuropsychology review},
  year    = {2017},
  doi     = {10.1007/s11065-016-9338-9},
  pmid    = {28092015},
  url     = {https://doi.org/10.1007/s11065-016-9338-9}
}

@article{webb2018-29721646,
  author  = {Webb, S. L. and Loh, V. and Lampit, A. and Bateman, J. E. and Birney, D. P.},
  title   = {{Meta-Analysis of the Effects of Computerized Cognitive Training on Executive Functions: a Cross-Disciplinary Taxonomy for Classifying Outcome Cognitive Factors}},
  journal = {Neuropsychology review},
  year    = {2018},
  doi     = {10.1007/s11065-018-9374-8},
  pmid    = {29721646},
  url     = {https://doi.org/10.1007/s11065-018-9374-8}
}

@article{vyshedskiy2022-35291958,
  author  = {Vyshedskiy, A. and Netson, R. and Fridberg, E. and Jagadeesan, P. and Arnold, M. and Barnett, S. and Gondalia, A. and Maslova, V. and others},
  title   = {{Boston cognitive assessment (BOCA) - a comprehensive self-administered smartphone- and computer-based at-home test for longitudinal tracking of cognitive performance}},
  journal = {BMC neurology},
  year    = {2022},
  doi     = {10.1186/s12883-022-02620-6},
  pmid    = {35291958},
  url     = {https://doi.org/10.1186/s12883-022-02620-6}
}

@article{choi2018-29454006,
  author  = {Choi, H. and Jin, K. H. and {Alzheimer’s Disease Neuroimaging Initiative}},
  title   = {{Predicting cognitive decline with deep learning of brain metabolism and amyloid imaging}},
  journal = {Behavioural brain research},
  year    = {2018},
  doi     = {10.1016/j.bbr.2018.02.017},
  pmid    = {29454006},
  url     = {https://doi.org/10.1016/j.bbr.2018.02.017}
}

@article{seixas2022-36061297,
  author  = {Seixas, Azizi A and Rajabli, Farid and Pericak-Vance, Margaret A and Jean-Louis, Girardin and Harms, Robbert L and Tarnanas, Ioannis},
  title   = {{Associations of digital neuro-signatures with molecular and neuroimaging measures of brain resilience: The altoida large cohort study}},
  journal = {Frontiers in psychiatry},
  year    = {2022},
  doi     = {10.3389/fpsyt.2022.899080},
  pmid    = {36061297},
  url     = {https://doi.org/10.3389/fpsyt.2022.899080}
}

@article{dhanam2026-42273832,
  author  = {Dhanam, Sreya and Sanderson-Cimino, Mark and Taylor, Jack Carson and Paolillo, Emily W and Fregly, Ray and Kwang, Winnie and Maruff, Paul and Wise, Amy and others},
  title   = {{Remote, self-administered, smartphone cognitive testing in a registry-based cohort: Feasibility, reliability, and validity findings}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2026},
  doi     = {10.1002/alz.71580},
  pmid    = {42273832},
  url     = {https://doi.org/10.1002/alz.71580}
}

@article{grueso2021-34583745,
  author  = {Grueso, S. and Viejo-Sobera, R.},
  title   = {{Machine learning methods for predicting progression from mild cognitive impairment to Alzheimer's disease dementia: a systematic review}},
  journal = {Alzheimer's research \& therapy},
  year    = {2021},
  doi     = {10.1186/s13195-021-00900-w},
  pmid    = {34583745},
  url     = {https://doi.org/10.1186/s13195-021-00900-w}
}

@article{wilson2022-35243008,
  author  = {Wilson, S. A. and Byrne, P. and Rodgers, S. E. and Maden, M.},
  title   = {{A Systematic Review of Smartphone and Tablet Use by Older Adults With and Without Cognitive Impairment}},
  journal = {Innovation in aging},
  year    = {2022},
  doi     = {10.1093/geroni/igac002},
  pmid    = {35243008},
  url     = {https://doi.org/10.1093/geroni/igac002}
}

@article{heffernan2019-30475762,
  author  = {Heffernan, M. and Andrews, G. and Fiatarone Singh, M. A. and Valenzuela, M. and Anstey, K. J. and Maeder, A. J. and McNeil, J. and Jorm, L. and others},
  title   = {{Maintain Your Brain: Protocol of a 3-Year Randomized Controlled Trial of a Personalized Multi-Modal Digital Health Intervention to Prevent Cognitive Decline Among Community Dwelling 55 to 77 Year Olds}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2019},
  doi     = {10.3233/jad-180572},
  pmid    = {30475762},
  url     = {https://doi.org/10.3233/jad-180572}
}

@article{racine2021-33078300,
  author  = {Racine, A. M. and Tommet, D. and D'Aquila, M. L. and Fong, T. G. and Gou, Y. and Tabloski, P. A. and Metzger, E. D. and Hshieh, T. T. and others},
  title   = {{Machine Learning to Develop and Internally Validate a Predictive Model for Post-operative Delirium in a Prospective, Observational Clinical Cohort Study of Older Surgical Patients}},
  journal = {Journal of general internal medicine},
  year    = {2021},
  doi     = {10.1007/s11606-020-06238-7},
  pmid    = {33078300},
  url     = {https://doi.org/10.1007/s11606-020-06238-7}
}

@article{scullin2022-34786698,
  author  = {Scullin, M. K. and Jones, W. E. and Phenis, R. and Beevers, S. and Rosen, S. and Dinh, K. and Kiselica, A. and Keefe, F. J. and others},
  title   = {{Using smartphone technology to improve prospective memory functioning: A randomized controlled trial}},
  journal = {Journal of the American Geriatrics Society},
  year    = {2022},
  doi     = {10.1111/jgs.17551},
  pmid    = {34786698},
  url     = {https://doi.org/10.1111/jgs.17551}
}

@article{grzybowski2024-38913289,
  author  = {Grzybowski, A. and Jin, K. and Zhou, J. and Pan, X. and Wang, M. and Ye, J. and Wong, T. Y.},
  title   = {{Retina Fundus Photograph-Based Artificial Intelligence Algorithms in Medicine: A Systematic Review}},
  journal = {Ophthalmology and therapy},
  year    = {2024},
  doi     = {10.1007/s40123-024-00981-4},
  pmid    = {38913289},
  url     = {https://doi.org/10.1007/s40123-024-00981-4}
}

@article{nguyen2020-32763427,
  author  = {Nguyen, M. and He, T. and An, L. and Alexander, D. C. and Feng, J. and Yeo, B. T. T. and {Alzheimer's Disease Neuroimaging Initiative}},
  title   = {{Predicting Alzheimer's disease progression using deep recurrent neural networks}},
  journal = {NeuroImage},
  year    = {2020},
  doi     = {10.1016/j.neuroimage.2020.117203},
  pmid    = {32763427},
  url     = {https://doi.org/10.1016/j.neuroimage.2020.117203}
}

@article{bateman2017-28855146,
  author  = {Bateman, D. R. and Srinivas, B. and Emmett, T. W. and Schleyer, T. K. and Holden, R. J. and Hendrie, H. C. and Callahan, C. M.},
  title   = {{Categorizing Health Outcomes and Efficacy of mHealth Apps for Persons With Cognitive Impairment: A Systematic Review}},
  journal = {Journal of medical Internet research},
  year    = {2017},
  doi     = {10.2196/jmir.7814},
  pmid    = {28855146},
  url     = {https://doi.org/10.2196/jmir.7814}
}

@article{saif2020-32665410,
  author  = {Saif, N. and Niotis, K. and Dominguez, M. and Hodes, J. F. and Woodbury, M. and Amini, Y. and Sadek, G. and Scheyer, O. and others},
  title   = {{Education Research: Online Alzheimer education for high school and college students: A randomized controlled trial}},
  journal = {Neurology},
  year    = {2020},
  doi     = {10.1212/wnl.0000000000009859},
  pmid    = {32665410},
  url     = {https://doi.org/10.1212/wnl.0000000000009859}
}

@article{moyle2018-29563027,
  author  = {Moyle, W. and Jones, C. and Murfield, J. and Thalib, L. and Beattie, E. and Shum, D. and O'Dwyer, S. and Mervin, M. C. and others},
  title   = {{Effect of a robotic seal on the motor activity and sleep patterns of older people with dementia, as measured by wearable technology: A cluster-randomised controlled trial}},
  journal = {Maturitas},
  year    = {2018},
  doi     = {10.1016/j.maturitas.2018.01.007},
  pmid    = {29563027},
  url     = {https://doi.org/10.1016/j.maturitas.2018.01.007}
}

@article{cote2020-33505979,
  author  = {Cote, A. C. and Phelps, R. J. and Kabiri, N. S. and Bhangu, J. S. and Thomas, K. K.},
  title   = {{Evaluation of Wearable Technology in Dementia: A Systematic Review and Meta-Analysis}},
  journal = {Frontiers in medicine},
  year    = {2020},
  doi     = {10.3389/fmed.2020.501104},
  pmid    = {33505979},
  url     = {https://doi.org/10.3389/fmed.2020.501104}
}

@article{irazoki2020-32373018,
  author  = {Irazoki, E. and Contreras-Somoza, L. M. and Toribio-Guzmán, J. M. and Jenaro-Río, C. and van der Roest, H. and Franco-Martín, M. A.},
  title   = {{Technologies for Cognitive Training and Cognitive Rehabilitation for People With Mild Cognitive Impairment and Dementia. A Systematic Review}},
  journal = {Frontiers in psychology},
  year    = {2020},
  doi     = {10.3389/fpsyg.2020.00648},
  pmid    = {32373018},
  url     = {https://doi.org/10.3389/fpsyg.2020.00648}
}

@article{lanoiselee2017-28350801,
  author  = {Lanoiselée, H. M. and Nicolas, G. and Wallon, D. and Rovelet-Lecrux, A. and Lacour, M. and Rousseau, S. and Richard, A. C. and Pasquier, F. and others},
  title   = {{APP, PSEN1, and PSEN2 mutations in early-onset Alzheimer disease: A genetic screening study of familial and sporadic cases}},
  journal = {PLoS medicine},
  year    = {2017},
  doi     = {10.1371/journal.pmed.1002270},
  pmid    = {28350801},
  url     = {https://doi.org/10.1371/journal.pmed.1002270}
}

@article{ramzan2019-31853655,
  author  = {Ramzan, F. and Khan, M. U. G. and Rehmat, A. and Iqbal, S. and Saba, T. and Rehman, A. and Mehmood, Z.},
  title   = {{A Deep Learning Approach for Automated Diagnosis and Multi-Class Classification of Alzheimer's Disease Stages Using Resting-State fMRI and Residual Neural Networks}},
  journal = {Journal of medical systems},
  year    = {2019},
  doi     = {10.1007/s10916-019-1475-2},
  pmid    = {31853655},
  url     = {https://doi.org/10.1007/s10916-019-1475-2}
}

@article{boriani2025-39855632,
  author  = {Boriani, Giuseppe and Mei, Davide Antonio and Lip, Gregory Y.H. and {ARISTOTELES consortium}},
  title   = {{A European-Multicenter Network for the Implementation of Artificial Intelligence to Manage Complexity and Comorbidities of Atrial Fibrillation Patients: The ARISTOTELES Consortium}},
  journal = {Thrombosis and Haemostasis},
  year    = {2025},
  doi     = {10.1055/a-2508-5708},
  pmid    = {39855632},
  url     = {https://doi.org/10.1055/a-2508-5708}
}

@article{fernandezcalvo2011-21266141,
  author  = {Fernández-Calvo, B. and Rodríguez-Pérez, R. and Contador, I. and Rubio-Santorum, A. and Ramos, F.},
  title   = {{[Efficacy of cognitive training programs based on new software technologies in patients with Alzheimer-type dementia]}},
  journal = {Psicothema},
  year    = {2011},
  pmid    = {21266141}
}

@article{simon2018-30103334,
  author  = {Simon, S. S. and Tusch, E. S. and Feng, N. C. and Håkansson, K. and Mohammed, A. H. and Daffner, K. R.},
  title   = {{Is Computerized Working Memory Training Effective in Healthy Older Adults? Evidence from a Multi-Site, Randomized Controlled Trial}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2018},
  doi     = {10.3233/jad-180455},
  pmid    = {30103334},
  url     = {https://doi.org/10.3233/jad-180455}
}

@article{tierney2010-20413868,
  author  = {Tierney, M. C. and Lermer, M. A.},
  title   = {{Computerized cognitive assessment in primary care to identify patients with suspected cognitive impairment}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2010},
  doi     = {10.3233/jad-2010-091672},
  pmid    = {20413868},
  url     = {https://doi.org/10.3233/jad-2010-091672}
}

@article{hartin2016-27485822,
  author  = {Hartin, P. J. and Nugent, C. D. and McClean, S. I. and Cleland, I. and Tschanz, J. T. and Clark, C. J. and Norton, M. C.},
  title   = {{The Empowering Role of Mobile Apps in Behavior Change Interventions: The Gray Matters Randomized Controlled Trial}},
  journal = {JMIR mHealth and uHealth},
  year    = {2016},
  doi     = {10.2196/mhealth.4878},
  pmid    = {27485822},
  url     = {https://doi.org/10.2196/mhealth.4878}
}

@article{qiu2020-32357201,
  author  = {Qiu, S. and Joshi, P. S. and Miller, M. I. and Xue, C. and Zhou, X. and Karjadi, C. and Chang, G. H. and Joshi, A. S. and others},
  title   = {{Development and validation of an interpretable deep learning framework for Alzheimer's disease classification}},
  journal = {Brain : a journal of neurology},
  year    = {2020},
  doi     = {10.1093/brain/awaa137},
  pmid    = {32357201},
  url     = {https://doi.org/10.1093/brain/awaa137}
}

@article{tsoy2021-34101783,
  author  = {Tsoy, E. and Zygouris, S. and Possin, K. L.},
  title   = {{Current State of Self-Administered Brief Computerized Cognitive Assessments for Detection of Cognitive Disorders in Older Adults: A Systematic Review}},
  journal = {The journal of prevention of Alzheimer's disease},
  year    = {2021},
  doi     = {10.14283/jpad.2021.11},
  pmid    = {34101783},
  url     = {https://doi.org/10.14283/jpad.2021.11}
}

@article{dilorito2022-35588315,
  author  = {Di Lorito, C. and Bosco, A. and Rai, H. and Craven, M. and McNally, D. and Todd, C. and Booth, V. and Cowley, A. and others},
  title   = {{A systematic literature review and meta-analysis on digital health interventions for people living with dementia and Mild Cognitive Impairment}},
  journal = {International journal of geriatric psychiatry},
  year    = {2022},
  doi     = {10.1002/gps.5730},
  pmid    = {35588315},
  url     = {https://doi.org/10.1002/gps.5730}
}

@article{blanco2023-37838690,
  author  = {Blanco, K. and Salcidua, S. and Orellana, P. and Sauma-Pérez, T. and León, T. and Steinmetz, L. C. L. and Ibañez, A. and Duran-Aniotz, C. and others},
  title   = {{Systematic review: fluid biomarkers and machine learning methods to improve the diagnosis from mild cognitive impairment to Alzheimer's disease}},
  journal = {Alzheimer's research \& therapy},
  year    = {2023},
  doi     = {10.1186/s13195-023-01304-8},
  pmid    = {37838690},
  url     = {https://doi.org/10.1186/s13195-023-01304-8}
}

@article{endres2014-25344383,
  author  = {Endres, K. and Fahrenholz, F. and Lotz, J. and Hiemke, C. and Teipel, S. and Lieb, K. and Tüscher, O. and Fellgiebel, A.},
  title   = {{Increased CSF APPs-α levels in patients with Alzheimer disease treated with acitretin}},
  journal = {Neurology},
  year    = {2014},
  doi     = {10.1212/wnl.0000000000001017},
  pmid    = {25344383},
  url     = {https://doi.org/10.1212/wnl.0000000000001017}
}

@article{govindarajan2025-40108173,
  author  = {Govindarajan, Sindhuja Tirumalai and Mamourian, Elizabeth and Erus, Güray and Abdulkadir, Ahmed and Melhem, Randa and Doshi, Jimit J. and Pomponio, Raymond and Tosun, Duygu and others},
  title   = {{Machine learning reveals distinct neuroanatomical signatures of cardiovascular and metabolic diseases in cognitively unimpaired individuals}},
  journal = {Nature Communications},
  year    = {2025},
  doi     = {10.1038/s41467-025-57867-7},
  pmid    = {40108173},
  url     = {https://doi.org/10.1038/s41467-025-57867-7}
}

@article{qin2024-38838690,
  author  = {Qin, Qiuyuan and Temkin-Greener, Helena and Veazie, Peter and Cai, Shubing},
  title   = {{Racial and ethnic differences in telemedicine use among community-dwelling older adults with dementia}},
  journal = {Journal of the American Geriatrics Society},
  year    = {2024},
  doi     = {10.1111/jgs.19039},
  pmid    = {38838690},
  url     = {https://doi.org/10.1111/jgs.19039}
}

@article{javeed2023-36720727,
  author  = {Javeed, A. and Dallora, A. L. and Berglund, J. S. and Ali, A. and Ali, L. and Anderberg, P.},
  title   = {{Machine Learning for Dementia Prediction: A Systematic Review and Future Research Directions}},
  journal = {Journal of medical systems},
  year    = {2023},
  doi     = {10.1007/s10916-023-01906-7},
  pmid    = {36720727},
  url     = {https://doi.org/10.1007/s10916-023-01906-7}
}

@article{frizzell2022-35358720,
  author  = {Frizzell, T. O. and Glashutter, M. and Liu, C. C. and Zeng, A. and Pan, D. and Hajra, S. G. and D'Arcy, R. C. N. and Song, X.},
  title   = {{Artificial intelligence in brain MRI analysis of Alzheimer's disease over the past 12 years: A systematic review}},
  journal = {Ageing research reviews},
  year    = {2022},
  doi     = {10.1016/j.arr.2022.101614},
  pmid    = {35358720},
  url     = {https://doi.org/10.1016/j.arr.2022.101614}
}

@article{djabelkhir2017-29200836,
  author  = {Djabelkhir, L. and Wu, Y. H. and Vidal, J. S. and Cristancho-Lacroix, V. and Marlats, F. and Lenoir, H. and Carno, A. and Rigaud, A. S.},
  title   = {{Computerized cognitive stimulation and engagement programs in older adults with mild cognitive impairment: comparing feasibility, acceptability, and cognitive and psychosocial effects}},
  journal = {Clinical interventions in aging},
  year    = {2017},
  doi     = {10.2147/cia.s145769},
  pmid    = {29200836},
  url     = {https://doi.org/10.2147/cia.s145769}
}

@article{lee2021-33947391,
  author  = {Lee, S. and Zhou, J. and Wong, W. T. and Liu, T. and Wu, W. K. K. and Wong, I. C. K. and Zhang, Q. and Tse, G.},
  title   = {{Glycemic and lipid variability for predicting complications and mortality in diabetes mellitus using machine learning}},
  journal = {BMC endocrine disorders},
  year    = {2021},
  doi     = {10.1186/s12902-021-00751-4},
  pmid    = {33947391},
  url     = {https://doi.org/10.1186/s12902-021-00751-4}
}

@article{sekhon2021-33308615,
  author  = {Sekhon, H. and Sekhon, K. and Launay, C. and Afililo, M. and Innocente, N. and Vahia, I. and Rej, S. and Beauchet, O.},
  title   = {{Telemedicine and the rural dementia population: A systematic review}},
  journal = {Maturitas},
  year    = {2021},
  doi     = {10.1016/j.maturitas.2020.09.001},
  pmid    = {33308615},
  url     = {https://doi.org/10.1016/j.maturitas.2020.09.001}
}

@article{lee2018-29515131,
  author  = {Lee, J. S. and Kim, C. and Shin, J. H. and Cho, H. and Shin, D. S. and Kim, N. and Kim, H. J. and Kim, Y. and others},
  title   = {{Machine Learning-based Individual Assessment of Cortical Atrophy Pattern in Alzheimer's Disease Spectrum: Development of the Classifier and Longitudinal Evaluation}},
  journal = {Scientific reports},
  year    = {2018},
  doi     = {10.1038/s41598-018-22277-x},
  pmid    = {29515131},
  url     = {https://doi.org/10.1038/s41598-018-22277-x}
}

@article{spasov2019-30654174,
  author  = {Spasov, S. and Passamonti, L. and Duggento, A. and Liò, P. and Toschi, N. and {Alzheimer's Disease Neuroimaging Initiative}},
  title   = {{A parameter-efficient deep learning approach to predict conversion from mild cognitive impairment to Alzheimer's disease}},
  journal = {NeuroImage},
  year    = {2019},
  doi     = {10.1016/j.neuroimage.2019.01.031},
  pmid    = {30654174},
  url     = {https://doi.org/10.1016/j.neuroimage.2019.01.031}
}

@article{dubois2026-41394895,
  author  = {Dubois, Kelly N. and Pal, Subhamoy and Maher, Amanda Cook and Heidebrink, Judith L. and Persad, Carol C. and Giordani, Bruno and Hampstead, Benjamin M. and Bakulski, Kelly M. and others},
  title   = {{Dementia etiology classification using NULISA plasma biomarkers and machine learning}},
  journal = {Alzheimer s \& Dementia},
  year    = {2026},
  doi     = {10.1002/alz.71603},
  pmid    = {41394895},
  url     = {https://doi.org/10.1002/alz.71603}
}

@article{gooding2016-26674122,
  author  = {Gooding, A. L. and Choi, J. and Fiszdon, J. M. and Wilkins, K. and Kirwin, P. D. and van Dyck, C. H. and Devanand, D. and Bell, M. D. and others},
  title   = {{Comparing three methods of computerised cognitive training for older adults with subclinical cognitive decline}},
  journal = {Neuropsychological rehabilitation},
  year    = {2016},
  doi     = {10.1080/09602011.2015.1118389},
  pmid    = {26674122},
  url     = {https://doi.org/10.1080/09602011.2015.1118389}
}

@article{guzmanparra2020-32442136,
  author  = {Guzman-Parra, J. and Barnestein-Fonseca, P. and Guerrero-Pertiñez, G. and Anderberg, P. and Jimenez-Fernandez, L. and Valero-Moreno, E. and Goodman-Casanova, J. M. and Cuesta-Vargas, A. and others},
  title   = {{Attitudes and Use of Information and Communication Technologies in Older Adults With Mild Cognitive Impairment or Early Stages of Dementia and Their Caregivers: Cross-Sectional Study}},
  journal = {Journal of medical Internet research},
  year    = {2020},
  doi     = {10.2196/17253},
  pmid    = {32442136},
  url     = {https://doi.org/10.2196/17253}
}

@article{tieges2015-25742756,
  author  = {Tieges, Z. and Stíobhairt, A. and Scott, K. and Suchorab, K. and Weir, A. and Parks, S. and Shenkin, S. and MacLullich, A.},
  title   = {{Development of a smartphone application for the objective detection of attentional deficits in delirium}},
  journal = {International psychogeriatrics},
  year    = {2015},
  doi     = {10.1017/s1041610215000186},
  pmid    = {25742756},
  url     = {https://doi.org/10.1017/s1041610215000186}
}

@article{li2014-25320813,
  author  = {Li, R. and Zhang, W. and Suk, H. I. and Wang, L. and Li, J. and Shen, D. and Ji, S.},
  title   = {{Deep learning based imaging data completion for improved brain disease diagnosis}},
  journal = {Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention},
  year    = {2014},
  doi     = {10.1007/978-3-319-10443-0_39},
  pmid    = {25320813},
  url     = {https://doi.org/10.1007/978-3-319-10443-0_39}
}

@article{jonsson2012-22801501,
  author  = {Jonsson, T. and Atwal, J. K. and Steinberg, S. and Snaedal, J. and Jonsson, P. V. and Bjornsson, S. and Stefansson, H. and Sulem, P. and others},
  title   = {{A mutation in APP protects against Alzheimer's disease and age-related cognitive decline}},
  journal = {Nature},
  year    = {2012},
  doi     = {10.1038/nature11283},
  pmid    = {22801501},
  url     = {https://doi.org/10.1038/nature11283}
}

@article{chan2021-34744026,
  author  = {Chan, J. Y. C. and Yau, S. T. Y. and Kwok, T. C. Y. and Tsoi, K. K. F.},
  title   = {{Diagnostic performance of digital cognitive tests for the identification of MCI and dementia: A systematic review}},
  journal = {Ageing research reviews},
  year    = {2021},
  doi     = {10.1016/j.arr.2021.101506},
  pmid    = {34744026},
  url     = {https://doi.org/10.1016/j.arr.2021.101506}
}

@article{meyer2017-28348957,
  author  = {Meyer, S. and Mueller, K. and Stuke, K. and Bisenius, S. and Diehl-Schmid, J. and Jessen, F. and Kassubek, J. and Kornhuber, J. and others},
  title   = {{Predicting behavioral variant frontotemporal dementia with pattern classification in multi-center structural MRI data}},
  journal = {NeuroImage. Clinical},
  year    = {2017},
  doi     = {10.1016/j.nicl.2017.02.001},
  pmid    = {28348957},
  url     = {https://doi.org/10.1016/j.nicl.2017.02.001}
}

@article{neal2021-33562749,
  author  = {Neal, D. and van den Berg, F. and Planting, C. and Ettema, T. and Dijkstra, K. and Finnema, E. and Dröes, R. M.},
  title   = {{Can Use of Digital Technologies by People with Dementia Improve Self-Management and Social Participation? A Systematic Review of Effect Studies}},
  journal = {Journal of clinical medicine},
  year    = {2021},
  doi     = {10.3390/jcm10040604},
  pmid    = {33562749},
  url     = {https://doi.org/10.3390/jcm10040604}
}

@article{ye2025-40324768,
  author  = {Ye, Mengfei and Liu, Zheng and Xie, Weigen and Shou, Mengna and Wang, S J and Lin, Xuebing and Xu, Yan and Yao, Miner and others},
  title   = {{Implementation of Telemedicine for Patients With Dementia and Their Caregivers: Scoping Review}},
  journal = {Journal of Medical Internet Research},
  year    = {2025},
  doi     = {10.2196/65667},
  pmid    = {40324768},
  url     = {https://doi.org/10.2196/65667}
}

@article{corbin2022-35388080,
  author  = {Corbin, Denis and Lesage, Frédéric},
  title   = {{Assessment of the predictive potential of cognitive scores from retinal images and retinal fundus metadata via deep learning using the CLSA database}},
  journal = {Scientific reports},
  year    = {2022},
  doi     = {10.1038/s41598-022-09719-3},
  pmid    = {35388080},
  url     = {https://doi.org/10.1038/s41598-022-09719-3}
}

@article{cheng2026-41644333,
  author  = {Cheng, Sheung-Tak and Ng, Peter H F},
  title   = {{Intervention Without Borders - an Automated Self-Guided AI-Enhanced Psychoeducation Intervention for Dementia Caregivers: Parallel-Group Randomized Waitlist-Controlled Trial}},
  journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry},
  year    = {2026},
  doi     = {10.1016/j.jagp.2026.01.001},
  pmid    = {41644333},
  url     = {https://doi.org/10.1016/j.jagp.2026.01.001}
}

@article{woodworth2023-37831492,
  author  = {Woodworth, E. C. and Briskin, E. A. and Plys, E. and Macklin, E. and Tatar, R. G. and Huberty, J. and Vranceanu, A. M.},
  title   = {{Mindfulness-Based App to Reduce Stress in Caregivers of Persons With Alzheimer Disease and Related Dementias: Protocol for a Single-Blind Feasibility Proof-of-Concept Randomized Controlled Trial}},
  journal = {JMIR research protocols},
  year    = {2023},
  doi     = {10.2196/50108},
  pmid    = {37831492},
  url     = {https://doi.org/10.2196/50108}
}

@article{hu2021-33625369,
  author  = {Hu, M. and Shu, X. and Yu, G. and Wu, X. and Välimäki, M. and Feng, H.},
  title   = {{A Risk Prediction Model Based on Machine Learning for Cognitive Impairment Among Chinese Community-Dwelling Elderly People With Normal Cognition: Development and Validation Study}},
  journal = {Journal of medical Internet research},
  year    = {2021},
  doi     = {10.2196/20298},
  pmid    = {33625369},
  url     = {https://doi.org/10.2196/20298}
}

@article{moon2020-32375661,
  author  = {Moon, S. and Park, K.},
  title   = {{The effect of digital reminiscence therapy on people with dementia: a pilot randomized controlled trial}},
  journal = {BMC geriatrics},
  year    = {2020},
  doi     = {10.1186/s12877-020-01563-2},
  pmid    = {32375661},
  url     = {https://doi.org/10.1186/s12877-020-01563-2}
}

@article{ding2022-35887956,
  author  = {Ding, Z. and Lee, T. L. and Chan, A. S.},
  title   = {{Digital Cognitive Biomarker for Mild Cognitive Impairments and Dementia: A Systematic Review}},
  journal = {Journal of clinical medicine},
  year    = {2022},
  doi     = {10.3390/jcm11144191},
  pmid    = {35887956},
  url     = {https://doi.org/10.3390/jcm11144191}
}

@article{xiao2025-40361211,
  author  = {Xiao, Xuan and Li, Yihui and Wu, Qiaoboyang and Liu, Xinting and Cao, Xu and Li, Maiping and Liu, Jing and Gong, Lianggeng and others},
  title   = {{Development and validation of a novel predictive model for dementia risk in middle-aged and elderly depression individuals: a large and longitudinal machine learning cohort study}},
  journal = {Alzheimer s Research \& Therapy},
  year    = {2025},
  doi     = {10.1186/s13195-025-01750-6},
  pmid    = {40361211},
  url     = {https://doi.org/10.1186/s13195-025-01750-6}
}

@article{chan2025-39827009,
  author  = {Chan, Lloyd L. Y. and Cerda, María Teresa Espinoza and Brodie, Matthew A D and Lord, Stephen R. and Taylor, Morag E.},
  title   = {{Daily-life walking speed, running duration and bedtime from wrist-worn sensors predict incident dementia: A watch walk – UK biobank study}},
  journal = {International Psychogeriatrics},
  year    = {2025},
  doi     = {10.1016/j.inpsyc.2024.100031},
  pmid    = {39827009},
  url     = {https://doi.org/10.1016/j.inpsyc.2024.100031}
}

@article{jiaming2023-37227755,
  author  = {Jiaming, Liang and Aranda Maria, P.},
  title   = {{The Use of Telehealth Among People Living With Dementia-Caregiver Dyads During the COVID-19 Pandemic: Scoping Review}},
  journal = {Journal of medical Internet research},
  year    = {2023},
  doi     = {10.2196/45045},
  pmid    = {37227755},
  url     = {https://doi.org/10.2196/45045}
}

@article{polk2025-40348870,
  author  = {Polk, S. E. and Öhman, F. and Hassenstab, J. and König, A. and Papp, K. V. and Schöll, M. and Berron, D.},
  title   = {{A scoping review of remote and unsupervised digital cognitive assessments in preclinical Alzheimer's disease}},
  journal = {NPJ digital medicine},
  year    = {2025},
  doi     = {10.1038/s41746-025-01583-5},
  pmid    = {40348870},
  url     = {https://doi.org/10.1038/s41746-025-01583-5}
}

@article{guo2020-32723713,
  author  = {Guo, Y. and Hao, Z. and Zhao, S. and Gong, J. and Yang, F.},
  title   = {{Artificial Intelligence in Health Care: Bibliometric Analysis}},
  journal = {Journal of medical Internet research},
  year    = {2020},
  doi     = {10.2196/18228},
  pmid    = {32723713},
  url     = {https://doi.org/10.2196/18228}
}

@article{stevens2025-41085219,
  author  = {Stevens, A. B. and Cho, J. and Birchfield, T. and Reese, J. and Han, G. and Thorud, J. L. and Ory, M. G.},
  title   = {{A randomized trial of two online platforms for dementia family caregivers: GamePlan4Care and Resources4Care}},
  journal = {Alzheimer's \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz.70690},
  pmid    = {41085219},
  url     = {https://doi.org/10.1002/alz.70690}
}

@article{brijnath2026-41719424,
  author  = {Brijnath, Bianca and Dang, Thu Ha and Enticott, Joanne and Tian, Yuan and Markusevska, Simona and Antoniades, Josefine and Nguyen, Tuan Anh and Gilbert, Andrew and others},
  title   = {{Evaluating the effects of the World Health Organisation's online intervention 'iSupport lite' to reduce burden in multilingual dementia carers: results from the Australian Draw-Care randomised clinical trial}},
  journal = {Age and ageing},
  year    = {2026},
  doi     = {10.1093/ageing/afag030},
  pmid    = {41719424},
  url     = {https://doi.org/10.1093/ageing/afag030}
}

@article{kalicki2021-33848360,
  author  = {Kalicki, A. V. and Moody, K. A. and Franzosa, E. and Gliatto, P. M. and Ornstein, K. A.},
  title   = {{Barriers to telehealth access among homebound older adults}},
  journal = {Journal of the American Geriatrics Society},
  year    = {2021},
  doi     = {10.1111/jgs.17163},
  pmid    = {33848360},
  url     = {https://doi.org/10.1111/jgs.17163}
}

@article{park2020-32258428,
  author  = {Park, J. H. and Cho, H. E. and Kim, J. H. and Wall, M. M. and Stern, Y. and Lim, H. and Yoo, S. and Kim, H. S. and others},
  title   = {{Machine learning prediction of incidence of Alzheimer's disease using large-scale administrative health data}},
  journal = {NPJ digital medicine},
  year    = {2020},
  doi     = {10.1038/s41746-020-0256-0},
  pmid    = {32258428},
  url     = {https://doi.org/10.1038/s41746-020-0256-0}
}

@article{schwenk2014-25171300,
  author  = {Schwenk, M. and Hauer, K. and Zieschang, T. and Englert, S. and Mohler, J. and Najafi, B.},
  title   = {{Sensor-derived physical activity parameters can predict future falls in people with dementia}},
  journal = {Gerontology},
  year    = {2014},
  doi     = {10.1159/000363136},
  pmid    = {25171300},
  url     = {https://doi.org/10.1159/000363136}
}

@article{cleretdelangavant2018-29986849,
  author  = {Cleret de Langavant, L. and Bayen, E. and Yaffe, K.},
  title   = {{Unsupervised Machine Learning to Identify High Likelihood of Dementia in Population-Based Surveys: Development and Validation Study}},
  journal = {Journal of medical Internet research},
  year    = {2018},
  doi     = {10.2196/10493},
  pmid    = {29986849},
  url     = {https://doi.org/10.2196/10493}
}

@article{jannati2024-38167251,
  author  = {Jannati, A. and Toro-Serey, C. and Gomes-Osman, J. and Banks, R. and Ciesla, M. and Showalter, J. and Bates, D. and Tobyne, S. and others},
  title   = {{Digital Clock and Recall is superior to the Mini-Mental State Examination for the detection of mild cognitive impairment and mild dementia}},
  journal = {Alzheimer's research \& therapy},
  year    = {2024},
  doi     = {10.1186/s13195-023-01367-7},
  pmid    = {38167251},
  url     = {https://doi.org/10.1186/s13195-023-01367-7}
}

@article{levine2018-28605446,
  author  = {Levine, D. M. and Lipsitz, SR. and Linder, J. A.},
  title   = {{Changes in Everyday and Digital Health Technology Use Among Seniors in Declining Health}},
  journal = {The journals of gerontology. Series A, Biological sciences and medical sciences},
  year    = {2018},
  doi     = {10.1093/gerona/glx116},
  pmid    = {28605446},
  url     = {https://doi.org/10.1093/gerona/glx116}
}

@article{willem2015-26322584,
  author  = {Willem, M. and Tahirovic, S. and Busche, M. A. and Ovsepian, S. V. and Chafai, M. and Kootar, S. and Hornburg, D. and Evans, L. D. and others},
  title   = {{η-Secretase processing of APP inhibits neuronal activity in the hippocampus}},
  journal = {Nature},
  year    = {2015},
  doi     = {10.1038/nature14864},
  pmid    = {26322584},
  url     = {https://doi.org/10.1038/nature14864}
}

@article{cruchaga2012-22312439,
  author  = {Cruchaga, C. and Haller, G. and Chakraverty, S. and Mayo, K. and Vallania, F. L. and Mitra, R. D. and Faber, K. and Williamson, J. and others},
  title   = {{Rare variants in APP, PSEN1 and PSEN2 increase risk for AD in late-onset Alzheimer's disease families}},
  journal = {PloS one},
  year    = {2012},
  doi     = {10.1371/journal.pone.0031039},
  pmid    = {22312439},
  url     = {https://doi.org/10.1371/journal.pone.0031039}
}

@article{veronese2025-40715606,
  author  = {Veronese, Nicola and Bolzetta, Francesco and Gallo, Livia and Durante, Giorgia and Vernuccio, Laura and Saccaro, Carlo and Gambino, Caterina Maria and Custodero, Carlo and others},
  title   = {{Clinical prediction models using artificial intelligence approaches in dementia}},
  journal = {Aging Clinical and Experimental Research},
  year    = {2025},
  doi     = {10.1007/s40520-025-03112-6},
  pmid    = {40715606},
  url     = {https://doi.org/10.1007/s40520-025-03112-6}
}

@article{alaka2025-41160465,
  author  = {Alaka, Shakiru A and Ngan, SoFong Cam and MacPherson, Rebecca E. K. and Pickett, William and Chen, Christopher and Sze, Siu Kwan},
  title   = {{Enhancing dementia risk prediction with heart rate and machine learning in the Canadian Longitudinal Study on Aging}},
  journal = {Journal of Alzheimer s Disease},
  year    = {2025},
  doi     = {10.1177/13872877251390562},
  pmid    = {41160465},
  url     = {https://doi.org/10.1177/13872877251390562}
}

@article{dijkstra2025-40622227,
  author  = {Dijkstra, Hidde and Parsons, Cathleen S and van Bremen, Hanne-Eva and Willems, Hanna C. and de Hond, Anne and Van Munster, Barbara C. and Doornberg, Job Nicolaas and Oosterhoff, Jacobien H. F.},
  title   = {{Machine learning-based prediction of short- and long-term mortality for shared decision-making in older hip fracture patients: the Dutch Hip Fracture Audit algorithms in 74,396 cases}},
  journal = {Acta Orthopaedica},
  year    = {2025},
  doi     = {10.2340/17453674.2025.44248},
  pmid    = {40622227},
  url     = {https://doi.org/10.2340/17453674.2025.44248}
}

@article{kang2025-39773247,
  author  = {Kang, Jae Myeong and Manjavong, Manchumad and Jin, Chengshi and Diaz, Adam and Ashford, Miriam Thiel and Eichenbaum, Joseph and Thorp, Emily and Wragg, Elizabeth and others},
  title   = {{Subjective cognitive decline predicts longitudinal neuropsychological test performance in an unsupervised online setting in the Brain Health Registry}},
  journal = {Alzheimer s Research \& Therapy},
  year    = {2025},
  doi     = {10.1186/s13195-024-01641-2},
  pmid    = {39773247},
  url     = {https://doi.org/10.1186/s13195-024-01641-2}
}

@article{amabili2025-40896828,
  author  = {Amabili, Giulio and Maranesi, Elvira and Margaritini, Arianna and Bonfigli, Anna Rita and Felici, Elisa and Barbarossa, Federico and Benadduci, Marco and Gosetto, Laëtitia and others},
  title   = {{Managing Cognitive Decline Through a Social Robot–Based Intervention: Protocol for the engAGE Proof of Concept and Randomized Controlled Trial}},
  journal = {JMIR Research Protocols},
  year    = {2025},
  doi     = {10.2196/67601},
  pmid    = {40896828},
  url     = {https://doi.org/10.2196/67601}
}

@article{mcwilliams2021-34276428,
  author  = {McWilliams, E. C. and Barbey, F. M. and Dyer, J. F. and Islam, M. N. and McGuinness, B. and Murphy, B. and Nolan, H. and Passmore, P. and others},
  title   = {{Feasibility of Repeated Assessment of Cognitive Function in Older Adults Using a Wireless, Mobile, Dry-EEG Headset and Tablet-Based Games}},
  journal = {Frontiers in psychiatry},
  year    = {2021},
  doi     = {10.3389/fpsyt.2021.574482},
  pmid    = {34276428},
  url     = {https://doi.org/10.3389/fpsyt.2021.574482}
}

@article{wen2020-32417716,
  author  = {Wen, J. and Thibeau-Sutre, E. and Diaz-Melo, M. and Samper-González, J. and Routier, A. and Bottani, S. and Dormont, D. and Durrleman, S. and others},
  title   = {{Convolutional neural networks for classification of Alzheimer's disease: Overview and reproducible evaluation}},
  journal = {Medical image analysis},
  year    = {2020},
  doi     = {10.1016/j.media.2020.101694},
  pmid    = {32417716},
  url     = {https://doi.org/10.1016/j.media.2020.101694}
}

@article{lee2022-37118071,
  author  = {Lee, J. and Burkett, B. J. and Min, H. K. and Senjem, M. L. and Lundt, E. S. and Botha, H. and Graff-Radford, J. and Barnard, L. R. and others},
  title   = {{Deep learning-based brain age prediction in normal aging and dementia}},
  journal = {Nature aging},
  year    = {2022},
  doi     = {10.1038/s43587-022-00219-7},
  pmid    = {37118071},
  url     = {https://doi.org/10.1038/s43587-022-00219-7}
}

@article{ebrahimighahnavieh2020-31837630,
  author  = {Ebrahimighahnavieh, M. A. and Luo, S. and Chiong, R.},
  title   = {{Deep learning to detect Alzheimer's disease from neuroimaging: A systematic literature review}},
  journal = {Computer methods and programs in biomedicine},
  year    = {2020},
  doi     = {10.1016/j.cmpb.2019.105242},
  pmid    = {31837630},
  url     = {https://doi.org/10.1016/j.cmpb.2019.105242}
}

@article{sacre2025-41110277,
  author  = {Sacre, Amber and Wall, Conor and Godfrey, Alan and Hetherington, Victoria and Byrne, Andrew and Barber, Robert},
  title   = {{Smartphone use by people with dementia: An exploratory survey}},
  journal = {Maturitas},
  year    = {2025},
  doi     = {10.1016/j.maturitas.2025.108751},
  pmid    = {41110277},
  url     = {https://doi.org/10.1016/j.maturitas.2025.108751}
}

@article{choi2024-41059393,
  author  = {Choi, Yoon Seong and Ngam, Pei Ing and Lee, Jeong Ryong and Hwang, Dosik and Tan, Eng-King and {Harvard Aging Brain Study} and {Australian Imaging Biomarkers and Lifestyle Study of Aging} and {Japanese Alzheimer’s Disease Neuroimaging Initiative} and others},
  title   = {{Deep learning-based amyloid PET harmonization to predict cognitive decline in non-demented elderly}},
  journal = {Radiology advances},
  year    = {2024},
  doi     = {10.1093/radadv/umae019},
  pmid    = {41059393},
  url     = {https://doi.org/10.1093/radadv/umae019}
}

@article{hao2024-39428420,
  author  = {Hao, Jinkui and Kwapong, William R and Shen, Ting and Fu, Huazhu and Xu, Yanwu and Lu, Qinkang and Liu, Shouyue and Zhang, Jiong and others},
  title   = {{Early detection of dementia through retinal imaging and trustworthy AI}},
  journal = {NPJ digital medicine},
  year    = {2024},
  doi     = {10.1038/s41746-024-01292-5},
  pmid    = {39428420},
  url     = {https://doi.org/10.1038/s41746-024-01292-5}
}

@article{yousefzadeh2024-38565579,
  author  = {Yousefzadeh, Nooshin and Tran, Charlie and Ramirez-Zamora, Adolfo and Chen, Jinghua and Fang, Ruogu and Thai, My T},
  title   = {{Neuron-level explainable AI for Alzheimer's Disease assessment from fundus images}},
  journal = {Scientific reports},
  year    = {2024},
  doi     = {10.1038/s41598-024-58121-8},
  pmid    = {38565579},
  url     = {https://doi.org/10.1038/s41598-024-58121-8}
}

@article{stamate2019-31890857,
  author  = {Stamate, D. and Kim, M. and Proitsi, P. and Westwood, S. and Baird, A. and Nevado-Holgado, A. and Hye, A. and Bos, I. and others},
  title   = {{A metabolite-based machine learning approach to diagnose Alzheimer-type dementia in blood: Results from the European Medical Information Framework for Alzheimer disease biomarker discovery cohort}},
  journal = {Alzheimer's \& dementia (New York, N. Y.)},
  year    = {2019},
  doi     = {10.1016/j.trci.2019.11.001},
  pmid    = {31890857},
  url     = {https://doi.org/10.1016/j.trci.2019.11.001}
}

@article{ford2019-31791325,
  author  = {Ford, E. and Rooney, P. and Oliver, S. and Hoile, R. and Hurley, P. and Banerjee, S. and van Marwijk, H. and Cassell, J.},
  title   = {{Identifying undetected dementia in UK primary care patients: a retrospective case-control study comparing machine-learning and standard epidemiological approaches}},
  journal = {BMC medical informatics and decision making},
  year    = {2019},
  doi     = {10.1186/s12911-019-0991-9},
  pmid    = {31791325},
  url     = {https://doi.org/10.1186/s12911-019-0991-9}
}

@article{roveletlecrux2006-16369530,
  author  = {Rovelet-Lecrux, A. and Hannequin, D. and Raux, G. and Le Meur, N. and Laquerrière, A. and Vital, A. and Dumanchin, C. and Feuillette, S. and others},
  title   = {{APP locus duplication causes autosomal dominant early-onset Alzheimer disease with cerebral amyloid angiopathy}},
  journal = {Nature genetics},
  year    = {2006},
  doi     = {10.1038/ng1718},
  pmid    = {16369530},
  url     = {https://doi.org/10.1038/ng1718}
}

@article{nguyen2025-41000210,
  author  = {Nguyen, Tran To Tran and Vu, Lan Duong Tuyet and Truong, Khoa Tri and Nguyen, Tuan Chau and Thai, Truc Thanh and Schofield, Penelope E. and Nguyen, Tuan Anh and Than, The Ha Ngoc and others},
  title   = {{Smartphone App-Based Psychoeducation for Caregivers of People with Dementia in Vietnam: A Pilot Randomized Controlled Trial}},
  journal = {Clinical Interventions in Aging},
  year    = {2025},
  doi     = {10.2147/cia.s551994},
  pmid    = {41000210},
  url     = {https://doi.org/10.2147/cia.s551994}
}

@article{nguyen2025-41158517,
  author  = {Nguyen, Tran To Tran and Vu, Lan Duong Tuyet and Nguyen, Tuan Anh and Truong, Khoa Tri and Thai, Truc Thanh and Than, The Ha Ngoc and Nguyen, Huan Thanh},
  title   = {{Mobile App Psychoeducation for Dementia Caregivers In Vietnam: A Randomized Controlled Trial}},
  journal = {Journal of Multidisciplinary Healthcare},
  year    = {2025},
  doi     = {10.2147/jmdh.s557573},
  pmid    = {41158517},
  url     = {https://doi.org/10.2147/jmdh.s557573}
}

@article{barnard2025-40577677,
  author  = {Barnard, Leland and Botha, Hugo and Corriveau‐Lecavalier, Nick and Graff‐Radford, Jonathan and Dicks, Ellen and Gogineni, Venkatsampath and Zhang, Gemeng and Burkett, Brian J. and others},
  title   = {{An FDG-PET–Based Machine Learning Framework to Support Neurologic Decision-Making in Alzheimer Disease and Related Disorders}},
  journal = {Neurology},
  year    = {2025},
  doi     = {10.1212/wnl.0000000000213831},
  pmid    = {40577677},
  url     = {https://doi.org/10.1212/wnl.0000000000213831}
}

@article{hua2026-41505195,
  author  = {Hua, Musen and Su, Jiacheng and Zhang, Fuyan and Chen, Shuya and Li, Jiaoyue and Yang, Li},
  title   = {{Effects of digital psychological interventions for family caregivers of people with dementia: a systematic review and meta-analysis}},
  journal = {Age and ageing},
  year    = {2026},
  doi     = {10.1093/ageing/afaf373},
  pmid    = {41505195},
  url     = {https://doi.org/10.1093/ageing/afaf373}
}

@article{coutrot2019-30883560,
  author  = {Coutrot, A. and Schmidt, S. and Coutrot, L. and Pittman, J. and Hong, L. and Wiener, J. M. and Hölscher, C. and Dalton, R. C. and others},
  title   = {{Virtual navigation tested on a mobile app is predictive of real-world wayfinding navigation performance}},
  journal = {PloS one},
  year    = {2019},
  doi     = {10.1371/journal.pone.0213272},
  pmid    = {30883560},
  url     = {https://doi.org/10.1371/journal.pone.0213272}
}

@article{diogo2022-35922851,
  author  = {Diogo, V. S. and Ferreira, H. A. and Prata, D. and {Alzheimer’s Disease Neuroimaging Initiative}},
  title   = {{Early diagnosis of Alzheimer's disease using machine learning: a multi-diagnostic, generalizable approach}},
  journal = {Alzheimer's research \& therapy},
  year    = {2022},
  doi     = {10.1186/s13195-022-01047-y},
  pmid    = {35922851},
  url     = {https://doi.org/10.1186/s13195-022-01047-y}
}

@article{leng2019-30553098,
  author  = {Leng, M. and Liu, P. and Zhang, P. and Hu, M. and Zhou, H. and Li, G. and Yin, H. and Chen, L.},
  title   = {{Pet robot intervention for people with dementia: A systematic review and meta-analysis of randomized controlled trials}},
  journal = {Psychiatry research},
  year    = {2019},
  doi     = {10.1016/j.psychres.2018.12.032},
  pmid    = {30553098},
  url     = {https://doi.org/10.1016/j.psychres.2018.12.032}
}

@article{severson2021-34334334,
  author  = {Severson, K. A. and Chahine, L. M. and Smolensky, L. A. and Dhuliawala, M. and Frasier, M. and Ng, K. and Ghosh, S. and Hu, J.},
  title   = {{Discovery of Parkinson's disease states and disease progression modelling: a longitudinal data study using machine learning}},
  journal = {The Lancet. Digital health},
  year    = {2021},
  doi     = {10.1016/s2589-7500(21)00101-1},
  pmid    = {34334334},
  url     = {https://doi.org/10.1016/s2589-7500(21)00101-1}
}

@article{zhao2021-34327210,
  author  = {Zhao, H. and You, J. and Peng, Y. and Feng, Y.},
  title   = {{Machine Learning Algorithm Using Electronic Chart-Derived Data to Predict Delirium After Elderly Hip Fracture Surgeries: A Retrospective Case-Control Study}},
  journal = {Frontiers in surgery},
  year    = {2021},
  doi     = {10.3389/fsurg.2021.634629},
  pmid    = {34327210},
  url     = {https://doi.org/10.3389/fsurg.2021.634629}
}

@article{goodall2021-32475166,
  author  = {Goodall, G. and Taraldsen, K. and Serrano, J. A.},
  title   = {{The use of technology in creating individualized, meaningful activities for people living with dementia: A systematic review}},
  journal = {Dementia (London, England)},
  year    = {2021},
  doi     = {10.1177/1471301220928168},
  pmid    = {32475166},
  url     = {https://doi.org/10.1177/1471301220928168}
}

@article{petrovic2020-32411643,
  author  = {Petrovic, M. and Gaggioli, A.},
  title   = {{Digital Mental Health Tools for Caregivers of Older Adults-A Scoping Review}},
  journal = {Frontiers in public health},
  year    = {2020},
  doi     = {10.3389/fpubh.2020.00128},
  pmid    = {32411643},
  url     = {https://doi.org/10.3389/fpubh.2020.00128}
}

@article{amini2024-38924662,
  author  = {Amini, S. and Hao, B. and Yang, J. and Karjadi, C. and Kolachalama, V. B. and Au, R. and Paschalidis, I. C.},
  title   = {{Prediction of Alzheimer's disease progression within 6 years using speech: A novel approach leveraging language models}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2024},
  doi     = {10.1002/alz.13886},
  pmid    = {38924662},
  url     = {https://doi.org/10.1002/alz.13886}
}

@article{fisher2019-31541187,
  author  = {Fisher, C. K. and Smith, A. M. and Walsh, JR. and Diseases, Coalition Against Major and Abbott and {Alliance for Aging Research} and {Alzheimer’s Association} and {Alzheimer’s Foundation of America} and others},
  title   = {{Machine learning for comprehensive forecasting of Alzheimer's Disease progression}},
  journal = {Scientific reports},
  year    = {2019},
  doi     = {10.1038/s41598-019-49656-2},
  pmid    = {31541187},
  url     = {https://doi.org/10.1038/s41598-019-49656-2}
}

@article{cabrejo2006-16959815,
  author  = {Cabrejo, L. and Guyant-Maréchal, L. and Laquerrière, A. and Vercelletto, M. and De la Fournière, F. and Thomas-Antérion, C. and Verny, C. and Letournel, F. and others},
  title   = {{Phenotype associated with APP duplication in five families}},
  journal = {Brain : a journal of neurology},
  year    = {2006},
  doi     = {10.1093/brain/awl237},
  pmid    = {16959815},
  url     = {https://doi.org/10.1093/brain/awl237}
}

@article{gabb2025-40435500,
  author  = {Gabb, Victoria Grace and Blackman, Jonathan and Morrison, Hamish Duncan and Li, Haoxuan and Kendrick, Adrian Hugh and Turner, Nicholas L and Greenwood, Rosemary and Biswas, Bijetri and others},
  title   = {{Longitudinal Remote Sleep and Cognitive Research in Older Adults With Mild Cognitive Impairment and Dementia: Prospective Feasibility Cohort Study}},
  journal = {JMIR Aging},
  year    = {2025},
  doi     = {10.2196/72824},
  pmid    = {40435500},
  url     = {https://doi.org/10.2196/72824}
}

@article{nascimento2025-41194522,
  author  = {Nascimento, Israel Júnior Borges do and Abdulazeem, Hebatullah Mohamed and Weerasekara, Ishanka and Sharifan, Amin and Bianco, Véronique and Kularathne, Indunil and Cunningham, Charnay and Sathian, Brijesh and others},
  title   = {{An Overview of Reviews on Telemedicine and Telehealth in Dementia Care: Mixed Methods Synthesis}},
  journal = {JMIR Mental Health},
  year    = {2025},
  doi     = {10.2196/75266},
  pmid    = {41194522},
  url     = {https://doi.org/10.2196/75266}
}

@article{nguyen2026-41546043,
  author  = {Nguyen, Phuong Anh and Din, Fareed Ud and Krug, Matthew and Jones, Rikki},
  title   = {{Use of explainable AI (xAI) in dementia detection and prognosis: a scoping review}},
  journal = {BMC Medical Informatics and Decision Making},
  year    = {2026},
  doi     = {10.1186/s12911-025-03279-y},
  pmid    = {41546043},
  url     = {https://doi.org/10.1186/s12911-025-03279-y}
}

@article{bafaloukou2025-39896868,
  author  = {Bafaloukou, Marirena and Schalkamp, Ann‐Kathrin and Fletcher‐Lloyd, Nan and Capstick, Alexander and Walsh, Chloe and Sandor, Cynthia and Kouchaki, Samaneh and Nilforooshan, Ramin and others},
  title   = {{An interpretable machine learning tool for in-home monitoring of agitation episodes in people living with dementia: a proof-of-concept study}},
  journal = {EClinicalMedicine},
  year    = {2025},
  doi     = {10.1016/j.eclinm.2024.103032},
  pmid    = {39896868},
  url     = {https://doi.org/10.1016/j.eclinm.2024.103032}
}

@article{lewis2001-11520987,
  author  = {Lewis, Jada M. and Dickson, Dennis W. and Lin, Wen-Lang and Chisholm, Louise and Corral, Anthony and Jones, Graham and Yen, Shu-Hui C. and Sahara, Naruhiko and Skipper, Lisa M. and Yager, Debra and Eckman, Chris and Hardy, John and Hutton, Mike and McGowan, Eileen M.},
  title   = {{Enhanced Neurofibrillary Degeneration in Transgenic Mice Expressing Mutant Tau and APP}},
  journal = {Science},
  year    = {2001},
  doi     = {10.1126/science.1058189},
  pmid    = {11520987},
  url     = {https://doi.org/10.1126/science.1058189}
}

@article{jutten2021-35095476,
  author  = {Jutten, R. J. and Rentz, D. M. and Fu, J. F. and Mayblyum, D. V. and Amariglio, R. E. and Buckley, R. F. and Properzi, M. J. and Maruff, P. and others},
  title   = {{Monthly At-Home Computerized Cognitive Testing to Detect Diminished Practice Effects in Preclinical Alzheimer's Disease}},
  journal = {Frontiers in aging neuroscience},
  year    = {2021},
  doi     = {10.3389/fnagi.2021.800126},
  pmid    = {35095476},
  url     = {https://doi.org/10.3389/fnagi.2021.800126}
}

@article{berron2024-38532080,
  author  = {Berron, D. and Glanz, W. and Clark, L. and Basche, K. and Grande, X. and Güsten, J. and Billette, O. V. and Hempen, I. and others},
  title   = {{A remote digital memory composite to detect cognitive impairment in memory clinic samples in unsupervised settings using mobile devices}},
  journal = {NPJ digital medicine},
  year    = {2024},
  doi     = {10.1038/s41746-024-00999-9},
  pmid    = {38532080},
  url     = {https://doi.org/10.1038/s41746-024-00999-9}
}

@article{vanderlip2024-39239893,
  author  = {Vanderlip, C. R. and Lee, M. D. and Stark, C. E. L.},
  title   = {{Cognitive modeling of the Mnemonic Similarity Task as a digital biomarker for Alzheimer's disease}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2024},
  doi     = {10.1002/alz.14163},
  pmid    = {39239893},
  url     = {https://doi.org/10.1002/alz.14163}
}

@article{cummings2022-35516416,
  author  = {Cummings, J. and Lee, G. and Nahed, P. and Kambar, M. E. Z. N. and Zhong, K. and Fonseca, J. and Taghva, K.},
  title   = {{Alzheimer's disease drug development pipeline: 2022}},
  journal = {Alzheimer's \& dementia (New York, N. Y.)},
  year    = {2022},
  doi     = {10.1002/trc2.12295},
  pmid    = {35516416},
  url     = {https://doi.org/10.1002/trc2.12295}
}

@article{tran2019-30875745,
  author  = {Tran, B. X. and Vu, G. T. and Ha, G. H. and Vuong, Q. H. and Ho, M. T. and Vuong, T. T. and La, V. P. and others},
  title   = {{Global Evolution of Research in Artificial Intelligence in Health and Medicine: A Bibliometric Study}},
  journal = {Journal of clinical medicine},
  year    = {2019},
  doi     = {10.3390/jcm8030360},
  pmid    = {30875745},
  url     = {https://doi.org/10.3390/jcm8030360}
}

@article{antonelli2022-34480857,
  author  = {Antonelli, M. and Penfold, R. S. and Merino, J. and Sudre, C. H. and Molteni, E. and Berry, S. and Canas, L. S. and Graham, M. S. and others},
  title   = {{Risk factors and disease profile of post-vaccination SARS-CoV-2 infection in UK users of the COVID Symptom Study app: a prospective, community-based, nested, case-control study}},
  journal = {The Lancet. Infectious diseases},
  year    = {2022},
  doi     = {10.1016/s1473-3099(21)00460-6},
  pmid    = {34480857},
  url     = {https://doi.org/10.1016/s1473-3099(21)00460-6}
}

@article{landi2020-32699826,
  author  = {Landi, I. and Glicksberg, B. S. and Lee, H. C. and Cherng, S. and Landi, G. and Danieletto, M. and Dudley, J. T. and Furlanello, C. and others},
  title   = {{Deep representation learning of electronic health records to unlock patient stratification at scale}},
  journal = {NPJ digital medicine},
  year    = {2020},
  doi     = {10.1038/s41746-020-0301-z},
  pmid    = {32699826},
  url     = {https://doi.org/10.1038/s41746-020-0301-z}
}

@article{fritz2015-26079569,
  author  = {Fritz, N. E. and Cheek, F. M. and Nichols-Larsen, D. S.},
  title   = {{Motor-Cognitive Dual-Task Training in Persons With Neurologic Disorders: A Systematic Review}},
  journal = {Journal of neurologic physical therapy : JNPT},
  year    = {2015},
  doi     = {10.1097/npt.0000000000000090},
  pmid    = {26079569},
  url     = {https://doi.org/10.1097/npt.0000000000000090}
}

@article{wang2025-41121436,
  author  = {Wang, Jin-Tao and Zhi, Nan and Xu, Gang and Geng, Jie-Li and Xiao, Jin-Wen and Li, Hai-Xia and Li, Jian-Ping and Xie, Xin-Yi and others},
  title   = {{Speech digital biomarker combined with fluid biomarkers predict cognitive impairment through machine learning}},
  journal = {Alzheimer's research \& therapy},
  year    = {2025},
  doi     = {10.1186/s13195-025-01877-6},
  pmid    = {41121436},
  url     = {https://doi.org/10.1186/s13195-025-01877-6}
}

@article{huijbers2024-39807355,
  author  = {Huijbers, Willem and Pinter, Nandor K and Spaltman, Mandy and Cornelis, Mike and Schmand, Ben and Alnaji, Baraa and Yargeau, Maxwell and Harlock, Sarah and others},
  title   = {{Clinical validity of IntelliSpace Cognition digital assessment platform in mild cognitive impairment}},
  journal = {Frontiers in psychology},
  year    = {2024},
  doi     = {10.3389/fpsyg.2024.1451843},
  pmid    = {39807355},
  url     = {https://doi.org/10.3389/fpsyg.2024.1451843}
}

@article{myers2024-39038282,
  author  = {Myers, Jennifer Rae and Bryk, Kelsey N and Madero, Erica N and McFarlane, Jacob and Campitelli, Anthony and Gills, Joshua and Jones, Megan and Paulson, Sally and others},
  title   = {{Initial Perspectives From Rural-Residing Adults on a Digital Cognitive Health Coaching Intervention: Exploratory Qualitative Analysis}},
  journal = {JMIR formative research},
  year    = {2024},
  doi     = {10.2196/51400},
  pmid    = {39038282},
  url     = {https://doi.org/10.2196/51400}
}

@article{kim2021-32990807,
  author  = {Kim, Ji-Young and Oh, Dongkyu and Sung, Kiyoung and Choi, Hongyoon and Paeng, Jin Chul and Cheon, Gi Jeong and Kang, Keon Wook and Lee, Dong Young and others},
  title   = {{Visual interpretation of [18F]Florbetaben PET supported by deep learning-based estimation of amyloid burden}},
  journal = {European journal of nuclear medicine and molecular imaging},
  year    = {2021},
  doi     = {10.1007/s00259-020-05044-x},
  pmid    = {32990807},
  url     = {https://doi.org/10.1007/s00259-020-05044-x}
}

@article{jo2020-33371874,
  author  = {Jo, Taeho and Nho, Kwangsik T. and Risacher, Shannon L. and Saykin, Andrew J. and {Alzheimer’s Disease Neuroimaging Initiative}},
  title   = {{Deep learning detection of informative features in tau PET for Alzheimer’s disease classification}},
  journal = {BMC Bioinformatics},
  year    = {2020},
  doi     = {10.1186/s12859-020-03848-0},
  pmid    = {33371874},
  url     = {https://doi.org/10.1186/s12859-020-03848-0}
}

@article{li2019-31201098,
  author  = {Li, H. and Habes, M. and Wolk, D. A. and Fan, Y.},
  title   = {{A deep learning model for early prediction of Alzheimer's disease dementia based on hippocampal magnetic resonance imaging data}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2019},
  doi     = {10.1016/j.jalz.2019.02.007},
  pmid    = {31201098},
  url     = {https://doi.org/10.1016/j.jalz.2019.02.007}
}

@article{manook2012-22427802,
  author  = {Manook, A. and Yousefi, B. H. and Willuweit, A. and Platzer, S. and Reder, S. and Voss, A. and Huisman, M. and Settles, M. and others},
  title   = {{Small-animal PET imaging of amyloid-beta plaques with [11C]PiB and its multi-modal validation in an APP/PS1 mouse model of Alzheimer's disease}},
  journal = {PloS one},
  year    = {2012},
  doi     = {10.1371/journal.pone.0031310},
  pmid    = {22427802},
  url     = {https://doi.org/10.1371/journal.pone.0031310}
}

@article{castellazzi2020-32595465,
  author  = {Castellazzi, G. and Cuzzoni, M. G. and Cotta Ramusino, M. and Martinelli, D. and Denaro, F. and Ricciardi, A. and Vitali, P. and Anzalone, N. and others},
  title   = {{A Machine Learning Approach for the Differential Diagnosis of Alzheimer and Vascular Dementia Fed by MRI Selected Features}},
  journal = {Frontiers in neuroinformatics},
  year    = {2020},
  doi     = {10.3389/fninf.2020.00025},
  pmid    = {32595465},
  url     = {https://doi.org/10.3389/fninf.2020.00025}
}

@article{deeken2019-30642650,
  author  = {Deeken, F. and Rezo, A. and Hinz, M. and Discher, R. and Rapp, M. A.},
  title   = {{Evaluation of Technology-Based Interventions for Informal Caregivers of Patients With Dementia-A Meta-Analysis of Randomized Controlled Trials}},
  journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry},
  year    = {2019},
  doi     = {10.1016/j.jagp.2018.12.003},
  pmid    = {30642650},
  url     = {https://doi.org/10.1016/j.jagp.2018.12.003}
}

@article{kale2024-39293530,
  author  = {Kale, M. and Wankhede, N. and Pawar, R. and Ballal, S. and Kumawat, R. and Goswami, M. and Khalid, M. and Taksande, B. and others},
  title   = {{AI-driven innovations in Alzheimer's disease: Integrating early diagnosis, personalized treatment, and prognostic modelling}},
  journal = {Ageing research reviews},
  year    = {2024},
  doi     = {10.1016/j.arr.2024.102497},
  pmid    = {39293530},
  url     = {https://doi.org/10.1016/j.arr.2024.102497}
}

@article{winchester2023-37654029,
  author  = {Winchester, L. M. and Harshfield, E. L. and Shi, L. and Badhwar, A. and Khleifat, A. A. and Clarke, N. and Dehsarvi, A. and Lengyel, I. and others},
  title   = {{Artificial intelligence for biomarker discovery in Alzheimer's disease and dementia}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2023},
  doi     = {10.1002/alz.13390},
  pmid    = {37654029},
  url     = {https://doi.org/10.1002/alz.13390}
}

@article{gill2020-32250302,
  author  = {Gill, S. and Mouches, P. and Hu, S. and Rajashekar, D. and MacMaster, F. P. and Smith, E. E. and Forkert, N. D. and Ismail, Z. and others},
  title   = {{Using Machine Learning to Predict Dementia from Neuropsychiatric Symptom and Neuroimaging Data}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2020},
  doi     = {10.3233/jad-191169},
  pmid    = {32250302},
  url     = {https://doi.org/10.3233/jad-191169}
}

@article{kim2019-30981204,
  author  = {Kim, J. P. and Kim, J. and Park, Y. H. and Park, S. B. and Lee, J. S. and Yoo, S. and Kim, E. J. and Kim, H. J. and others},
  title   = {{Machine learning based hierarchical classification of frontotemporal dementia and Alzheimer's disease}},
  journal = {NeuroImage. Clinical},
  year    = {2019},
  doi     = {10.1016/j.nicl.2019.101811},
  pmid    = {30981204},
  url     = {https://doi.org/10.1016/j.nicl.2019.101811}
}

@article{alatrany2024-38302557,
  author  = {Alatrany, A. S. and Khan, W. and Hussain, A. and Kolivand, H. and Al-Jumeily, D.},
  title   = {{An explainable machine learning approach for Alzheimer's disease classification}},
  journal = {Scientific reports},
  year    = {2024},
  doi     = {10.1038/s41598-024-51985-w},
  pmid    = {38302557},
  url     = {https://doi.org/10.1038/s41598-024-51985-w}
}

@article{boyle2022-36550456,
  author  = {Boyle, L. D. and Husebo, B. S. and Vislapuu, M.},
  title   = {{Promotors and barriers to the implementation and adoption of assistive technology and telecare for people with dementia and their caregivers: a systematic review of the literature}},
  journal = {BMC health services research},
  year    = {2022},
  doi     = {10.1186/s12913-022-08968-2},
  pmid    = {36550456},
  url     = {https://doi.org/10.1186/s12913-022-08968-2}
}

@article{cho2023-36434931,
  author  = {Cho, E. and Shin, J. and Seok, J. W. and Lee, H. and Lee, K. H. and Jang, J. and Heo, S. J. and Kang, B.},
  title   = {{The effectiveness of non-pharmacological interventions using information and communication technologies for behavioral and psychological symptoms of dementia: A systematic review and meta-analysis}},
  journal = {International journal of nursing studies},
  year    = {2023},
  doi     = {10.1016/j.ijnurstu.2022.104392},
  pmid    = {36434931},
  url     = {https://doi.org/10.1016/j.ijnurstu.2022.104392}
}

@article{chew2025-39039178,
  author  = {Chew, E. Y. and Burns, S. A. and Abraham, A. G. and Bakhoum, M. F. and Beckman, J. A. and Chui, T. Y. P. and Finger, R. P. and Frangi, A. F. and others},
  title   = {{Standardization and clinical applications of retinal imaging biomarkers for cardiovascular disease: a Roadmap from an NHLBI workshop}},
  journal = {Nature reviews. Cardiology},
  year    = {2025},
  doi     = {10.1038/s41569-024-01060-8},
  pmid    = {39039178},
  url     = {https://doi.org/10.1038/s41569-024-01060-8}
}

@article{lyall2023-37496259,
  author  = {Lyall, D. M. and Kormilitzin, A. and Lancaster, C. and Sousa, J. and Petermann-Rocha, F. and Buckley, C. and Harshfield, E. L. and Iveson, M. H. and others},
  title   = {{Artificial intelligence for dementia-Applied models and digital health}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2023},
  doi     = {10.1002/alz.13391},
  pmid    = {37496259},
  url     = {https://doi.org/10.1002/alz.13391}
}

@article{liu2020-31837471,
  author  = {Liu, M. and Li, F. and Yan, H. and Wang, K. and Ma, Y. and {Alzheimer’s Disease Neuroimaging Initiative} and Shen, L. and Xu, M.},
  title   = {{A multi-model deep convolutional neural network for automatic hippocampus segmentation and classification in Alzheimer's disease}},
  journal = {NeuroImage},
  year    = {2020},
  doi     = {10.1016/j.neuroimage.2019.116459},
  pmid    = {31837471},
  url     = {https://doi.org/10.1016/j.neuroimage.2019.116459}
}

@article{malioukis2026-41743052,
  author  = {Malioukis, Alex and Snead, R Sterling and Marczika, Julia and Ambalavanan, Radha and Towett, Gideon and Mbogori-Kairichi, Mercy},
  title   = {{Digital biomarkers for early agitation detection in dementia: a scoping review of emerging wearable and smart technologies for personalized care}},
  journal = {Frontiers in Neurology},
  year    = {2026},
  doi     = {10.3389/fneur.2026.1683517},
  pmid    = {41743052},
  url     = {https://doi.org/10.3389/fneur.2026.1683517}
}

@article{allard2014-25536290,
  author  = {Allard, M. and Husky, M. and Catheline, G. and Pelletier, A. and Dilharreguy, B. and Amieva, H. and Pérès, K. and Foubert-Samier, A. and others},
  title   = {{Mobile technologies in the early detection of cognitive decline}},
  journal = {PloS one},
  year    = {2014},
  doi     = {10.1371/journal.pone.0112197},
  pmid    = {25536290},
  url     = {https://doi.org/10.1371/journal.pone.0112197}
}

@article{bemelmans2012-21450215,
  author  = {Bemelmans, R. and Gelderblom, G. J. and Jonker, P. and de Witte, L.},
  title   = {{Socially assistive robots in elderly care: a systematic review into effects and effectiveness}},
  journal = {Journal of the American Medical Directors Association},
  year    = {2012},
  doi     = {10.1016/j.jamda.2010.10.002},
  pmid    = {21450215},
  url     = {https://doi.org/10.1016/j.jamda.2010.10.002}
}

@article{kloppel2008-18835868,
  author  = {Klöppel, S. and Stonnington, C. M. and Barnes, J. and Chen, F. and Chu, C. and Good, C. D. and Mader, I. and Mitchell, L. A. and others},
  title   = {{Accuracy of dementia diagnosis: a direct comparison between radiologists and a computerized method}},
  journal = {Brain : a journal of neurology},
  year    = {2008},
  doi     = {10.1093/brain/awn239},
  pmid    = {18835868},
  url     = {https://doi.org/10.1093/brain/awn239}
}

@article{bayat2021-34127064,
  author  = {Bayat, S. and Babulal, G. M. and Schindler, S. E. and Fagan, A. M. and Morris, J. C. and Mihailidis, A. and Roe, C. M.},
  title   = {{GPS driving: a digital biomarker for preclinical Alzheimer disease}},
  journal = {Alzheimer's research \& therapy},
  year    = {2021},
  doi     = {10.1186/s13195-021-00852-1},
  pmid    = {34127064},
  url     = {https://doi.org/10.1186/s13195-021-00852-1}
}

@article{jin2020-32714766,
  author  = {Jin, D. and Zhou, B. and Han, Y. and Ren, J. and Han, T. and Liu, B. and Lu, J. and Song, C. and others},
  title   = {{Generalizable, Reproducible, and Neuroscientifically Interpretable Imaging Biomarkers for Alzheimer's Disease}},
  journal = {Advanced science (Weinheim, Baden-Wurttemberg, Germany)},
  year    = {2020},
  doi     = {10.1002/advs.202000675},
  pmid    = {32714766},
  url     = {https://doi.org/10.1002/advs.202000675}
}

@article{buegler2020-32832589,
  author  = {Buegler, M. and Harms, R. and Balasa, M. and Meier, I. B. and Exarchos, T. and Rai, L. and Boyle, R. and Tort, A. and others},
  title   = {{Digital biomarker-based individualized prognosis for people at risk of dementia}},
  journal = {Alzheimer's \& dementia (Amsterdam, Netherlands)},
  year    = {2020},
  doi     = {10.1002/dad2.12073},
  pmid    = {32832589},
  url     = {https://doi.org/10.1002/dad2.12073}
}

@article{jin2019-31359864,
  author  = {Jin, Y. and Jing, M. and Ma, X.},
  title   = {{Effects of Digital Device Ownership on Cognitive Decline in a Middle-Aged and Elderly Population: Longitudinal Observational Study}},
  journal = {Journal of medical Internet research},
  year    = {2019},
  doi     = {10.2196/14210},
  pmid    = {31359864},
  url     = {https://doi.org/10.2196/14210}
}

@article{xue2021-34465384,
  author  = {Xue, C. and Karjadi, C. and Paschalidis, I. C. and Au, R. and Kolachalama, V. B.},
  title   = {{Detection of dementia on voice recordings using deep learning: a Framingham Heart Study}},
  journal = {Alzheimer's research \& therapy},
  year    = {2021},
  doi     = {10.1186/s13195-021-00888-3},
  pmid    = {34465384},
  url     = {https://doi.org/10.1186/s13195-021-00888-3}
}

@article{bachli2020-31841681,
  author  = {Bachli, M. B. and Sedeño, L. and Ochab, J. K. and Piguet, O. and Kumfor, F. and Reyes, P. and Torralva, T. and Roca, M. and others},
  title   = {{Evaluating the reliability of neurocognitive biomarkers of neurodegenerative diseases across countries: A machine learning approach}},
  journal = {NeuroImage},
  year    = {2020},
  doi     = {10.1016/j.neuroimage.2019.116456},
  pmid    = {31841681},
  url     = {https://doi.org/10.1016/j.neuroimage.2019.116456}
}

@article{tzimourta2021-33588710,
  author  = {Tzimourta, K. D. and Christou, V. and Tzallas, A. T. and Giannakeas, N. and Astrakas, L. G. and Angelidis, P. and Tsalikakis, D. and Tsipouras, M. G.},
  title   = {{Machine Learning Algorithms and Statistical Approaches for Alzheimer's Disease Analysis Based on Resting-State EEG Recordings: A Systematic Review}},
  journal = {International journal of neural systems},
  year    = {2021},
  doi     = {10.1142/s0129065721300023},
  pmid    = {33588710},
  url     = {https://doi.org/10.1142/s0129065721300023}
}

@article{pera2013-23224319,
  author  = {Pera, M. and Alcolea, D. and Sánchez-Valle, R. and Guardia-Laguarta, C. and Colom-Cadena, M. and Badiola, N. and Suárez-Calvet, M. and Lladó, A. and others},
  title   = {{Distinct patterns of APP processing in the CNS in autosomal-dominant and sporadic Alzheimer disease}},
  journal = {Acta neuropathologica},
  year    = {2013},
  doi     = {10.1007/s00401-012-1062-9},
  pmid    = {23224319},
  url     = {https://doi.org/10.1007/s00401-012-1062-9}
}

@article{hu2020-33551735,
  author  = {Hu, J. and Qing, Z. and Liu, R. and Zhang, X. and Lv, P. and Wang, M. and Wang, Y. and He, K. and others},
  title   = {{Deep Learning-Based Classification and Voxel-Based Visualization of Frontotemporal Dementia and Alzheimer's Disease}},
  journal = {Frontiers in neuroscience},
  year    = {2020},
  doi     = {10.3389/fnins.2020.626154},
  pmid    = {33551735},
  url     = {https://doi.org/10.3389/fnins.2020.626154}
}

@article{pawar2026-612ec977,
  author  = {Pawar, Diksha and Boaddh, Jayshree and Patidar, Prof. Rahul},
  title   = {{Longitudinal Structural MRI-Based Deep Learning And Radiomics Features For Predicting Alzheimer's Disease Progression}},
  journal = {Zenodo (CERN European Organization for Nuclear Research)},
  year    = {2026},
  doi     = {10.5281/zenodo.18620944},
  url     = {https://doi.org/10.5281/zenodo.18620944}
}

@article{jain2025-41213043,
  author  = {Jain, Sneha S. and Sun, Tony and Pierson, Emma and Oliver, Francisco Roedan and Malta, Paloma P and Castillo, Michelle and Wan, Ningxin and Alishetti, Shudhanshu and others},
  title   = {{Detecting Transthyretin Cardiac Amyloidosis With Artificial Intelligence}},
  journal = {JAMA Cardiology},
  year    = {2025},
  doi     = {10.1001/jamacardio.2025.4591},
  pmid    = {41213043},
  url     = {https://doi.org/10.1001/jamacardio.2025.4591}
}

@article{zhang2025-39838390,
  author  = {Zhang, Xiaoang and Liao, Yu‐Ping and Zhang, Daying and Liu, Weichen and Wang, Zhijian and Jin, Yaxin and Chen, Shushu and Wei, Jianmei},
  title   = {{Explainable machine learning models for identifying mild cognitive impairment in older patients with chronic pain}},
  journal = {BMC Nursing},
  year    = {2025},
  doi     = {10.1186/s12912-025-02723-8},
  pmid    = {39838390},
  url     = {https://doi.org/10.1186/s12912-025-02723-8}
}

@article{krishnan2026-42389671,
  author  = {Krishnan, Laya and Gunasekaran, Gaurie and Dhore, Tamanna and Lauinger, Alexa and Kolachalama, Vijaya and Pappu, Suguna},
  title   = {{Leveraging artificial intelligence for analysis of the gut microbiome for dementia diagnosis: a scoping review and discussion}},
  journal = {Frontiers in Dementia},
  year    = {2026},
  doi     = {10.3389/frdem.2026.1865441},
  pmid    = {42389671},
  url     = {https://doi.org/10.3389/frdem.2026.1865441}
}

@article{rezaii2025-41195302,
  author  = {Rezaii, Neguine and Wong, Bonnie and Aisen, Paul and Beckett, Laurel A. and Dage, Jeffrey L. and Eloyan, Ani and Foroud, Tatiana M. and Womack, Kyle B. and others},
  title   = {{Voiceprints of cognitive impairment: analyzing digital voice for early detection of Alzheimer’s and related dementias}},
  journal = {npj Dementia},
  year    = {2025},
  doi     = {10.1038/s44400-025-00040-0},
  pmid    = {41195302},
  url     = {https://doi.org/10.1038/s44400-025-00040-0}
}

@article{rodriguezsalgado2021-33216033,
  author  = {Rodríguez-Salgado, A. M. and Llibre-Guerra, J. J. and Tsoy, E. and Peñalver-Guia, A. I. and Bringas, G. and Erlhoff, S. J. and Kramer, J. H. and Allen, I. E. and others},
  title   = {{A Brief Digital Cognitive Assessment for Detection of Cognitive Impairment in Cuban Older Adults}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2021},
  doi     = {10.3233/jad-200985},
  pmid    = {33216033},
  url     = {https://doi.org/10.3233/jad-200985}
}

@article{serraano2019-31412893,
  author  = {Serra-Añó, P. and Pedrero-Sánchez, J. F. and Hurtado-Abellán, J. and Inglés, M. and Espí-López, G. V. and López-Pascual, J.},
  title   = {{Mobility assessment in people with Alzheimer disease using smartphone sensors}},
  journal = {Journal of neuroengineering and rehabilitation},
  year    = {2019},
  doi     = {10.1186/s12984-019-0576-y},
  pmid    = {31412893},
  url     = {https://doi.org/10.1186/s12984-019-0576-y}
}

@article{toniolo2024-38623387,
  author  = {Toniolo, S. and Zhao, S. and Scholcz, A. and Amein, B. and Ganse-Dumrath, A. and Heslegrave, A. J. and Thompson, S. and Manohar, S. and others},
  title   = {{Relationship of plasma biomarkers to digital cognitive tests in Alzheimer's disease}},
  journal = {Alzheimer's \& dementia (Amsterdam, Netherlands)},
  year    = {2024},
  doi     = {10.1002/dad2.12590},
  pmid    = {38623387},
  url     = {https://doi.org/10.1002/dad2.12590}
}

@article{taylor2023-37180971,
  author  = {Taylor, J. C. and Heuer, H. W. and Clark, A. L. and Wise, A. B. and Manoochehri, M. and Forsberg, L. and Mester, C. and Rao, M. and others},
  title   = {{Feasibility and acceptability of remote smartphone cognitive testing in frontotemporal dementia research}},
  journal = {Alzheimer's \& dementia (Amsterdam, Netherlands)},
  year    = {2023},
  doi     = {10.1002/dad2.12423},
  pmid    = {37180971},
  url     = {https://doi.org/10.1002/dad2.12423}
}

@article{bruno2024-39258756,
  author  = {Bruno, Davide and Jauregi-Zinkunegi, Ainara and Bock, Jason R and {Alzheimer's Disease Neuroimaging Initiative}},
  title   = {{Predicting CDR status over 36 months with a recall-based digital cognitive biomarker}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2024},
  doi     = {10.1002/alz.14213},
  pmid    = {39258756},
  url     = {https://doi.org/10.1002/alz.14213}
}

@article{thompson2024-39301587,
  author  = {Thompson, Louisa I and De Vito, Alyssa N and Kunicki, Zachary J and Emrani, Sheina and Strenger, Jennifer and Nester, Caroline and Harrington, Karra D and Roque, Nelson and others},
  title   = {{Psychometric and adherence considerations for high-frequency, smartphone-based cognitive screening protocols in older adults}},
  journal = {Journal of the International Neuropsychological Society : JINS},
  year    = {2024},
  doi     = {10.1017/s1355617724000328},
  pmid    = {39301587},
  url     = {https://doi.org/10.1017/s1355617724000328}
}

@article{ding2024-38426173,
  author  = {Ding, Huitong and Kim, Minzae and Searls, Edward and Sunderaraman, Preeti and De Anda-Duran, Ileana and Low, Spencer and Popp, Zachary and Hwang, Phillip H and others},
  title   = {{Digital neuropsychological measures by defense automated neurocognitive assessment: reference values and clinical correlates}},
  journal = {Frontiers in neurology},
  year    = {2024},
  doi     = {10.3389/fneur.2024.1340710},
  pmid    = {38426173},
  url     = {https://doi.org/10.3389/fneur.2024.1340710}
}

@article{wang2024-38476660,
  author  = {Wang, Jing and Zhou, Zheping and Cheng, Shanshan and Zhou, Li and Sun, Xiaoou and Song, Ziyang and Wu, Zhiwei and Lu, Jinhua and others},
  title   = {{Dual-task turn velocity - a novel digital biomarker for mild cognitive impairment and dementia}},
  journal = {Frontiers in aging neuroscience},
  year    = {2024},
  doi     = {10.3389/fnagi.2024.1304265},
  pmid    = {38476660},
  url     = {https://doi.org/10.3389/fnagi.2024.1304265}
}

@article{tang2020-32235884,
  author  = {Tang, Fengyi and Uchendu, Ikechukwu and Wang, Fei and Dodge, Hiroko H and Zhou, Jiayu},
  title   = {{Scalable diagnostic screening of mild cognitive impairment using AI dialogue agent}},
  journal = {Scientific reports},
  year    = {2020},
  doi     = {10.1038/s41598-020-61994-0},
  pmid    = {32235884},
  url     = {https://doi.org/10.1038/s41598-020-61994-0}
}

@article{toniolo2025-39886066,
  author  = {Toniolo, Sofia and Attaallah, Bahaaeddin and Maio, Maria Raquel and Tabi, Younes Adam and Slavkova, Elitsa and Klar, Verena Svenja and Saleh, Youssuf and Idris, Mohamad Imran and others},
  title   = {{Performance and validation of a digital memory test across the Alzheimer's disease continuum}},
  journal = {Brain communications},
  year    = {2025},
  doi     = {10.1093/braincomms/fcaf024},
  pmid    = {39886066},
  url     = {https://doi.org/10.1093/braincomms/fcaf024}
}

@article{xu2022-36450252,
  author  = {Xu, Jielin and Mao, Chengsheng and Hou, Yuan and Luo, Yuan and Binder, Jessica L and Zhou, Yadi and Bekris, Lynn M and Shin, Jiyoung and others},
  title   = {{Interpretable deep learning translation of GWAS and multi-omics findings to identify pathobiology and drug repurposing in Alzheimer's disease}},
  journal = {Cell reports},
  year    = {2022},
  doi     = {10.1016/j.celrep.2022.111717},
  pmid    = {36450252},
  url     = {https://doi.org/10.1016/j.celrep.2022.111717}
}

@article{castillobarnes2020-32284705,
  author  = {Castillo-Barnes, Diego and Su, Li and Ramírez, Javier and Salas-Gonzalez, Diego and Martinez-Murcia, Francisco J and Illan, Ignacio A and Segovia, Fermin and Ortiz, Andres and others},
  title   = {{Autosomal Dominantly Inherited Alzheimer Disease: Analysis of genetic subgroups by Machine Learning}},
  journal = {An international journal on information fusion},
  year    = {2020},
  doi     = {10.1016/j.inffus.2020.01.001},
  pmid    = {32284705},
  url     = {https://doi.org/10.1016/j.inffus.2020.01.001}
}

@article{cotten2017-28817928,
  author  = {Cotten, Shelia R.},
  title   = {{Examining the Roles of Technology in Aging and Quality of Life}},
  journal = {The Journals of Gerontology Series B},
  year    = {2017},
  doi     = {10.1093/geronb/gbx109},
  pmid    = {28817928},
  url     = {https://doi.org/10.1093/geronb/gbx109}
}

@article{dugstad2019-31182093,
  author  = {Dugstad, J. and Eide, T. and Nilsen, E. R. and Eide, H.},
  title   = {{Towards successful digital transformation through co-creation: a longitudinal study of a four-year implementation of digital monitoring technology in residential care for persons with dementia}},
  journal = {BMC health services research},
  year    = {2019},
  doi     = {10.1186/s12913-019-4191-1},
  pmid    = {31182093},
  url     = {https://doi.org/10.1186/s12913-019-4191-1}
}

@article{muller2019-30837580,
  author  = {Müller, S. and Herde, L. and Preische, O. and Zeller, A. and Heymann, P. and Robens, S. and Elbing, U. and Laske, C.},
  title   = {{Diagnostic value of digital clock drawing test in comparison with CERAD neuropsychological battery total score for discrimination of patients in the early course of Alzheimer's disease from healthy individuals}},
  journal = {Scientific reports},
  year    = {2019},
  doi     = {10.1038/s41598-019-40010-0},
  pmid    = {30837580},
  url     = {https://doi.org/10.1038/s41598-019-40010-0}
}

@article{gao2023-35668045,
  author  = {Gao, F. and Lv, X. and Dai, L. and Wang, Q. and Wang, P. and Cheng, Z. and Xie, Q. and Ni, M. and others},
  title   = {{A combination model of AD biomarkers revealed by machine learning precisely predicts Alzheimer's dementia: China Aging and Neurodegenerative Initiative (CANDI) study}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2023},
  doi     = {10.1002/alz.12700},
  pmid    = {35668045},
  url     = {https://doi.org/10.1002/alz.12700}
}

@article{berron2024-38867417,
  author  = {Berron, D. and Olsson, E. and Andersson, F. and Janelidze, S. and Tideman, P. and Düzel, E. and Palmqvist, S. and Stomrud, E. and others},
  title   = {{Remote and unsupervised digital memory assessments can reliably detect cognitive impairment in Alzheimer's disease}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2024},
  doi     = {10.1002/alz.13919},
  pmid    = {38867417},
  url     = {https://doi.org/10.1002/alz.13919}
}

@article{chen2020-33257744,
  author  = {Chen, S. and Stromer, D. and Alabdalrahim, H. A. and Schwab, S. and Weih, M. and Maier, A.},
  title   = {{Automatic dementia screening and scoring by applying deep learning on clock-drawing tests}},
  journal = {Scientific reports},
  year    = {2020},
  doi     = {10.1038/s41598-020-74710-9},
  pmid    = {33257744},
  url     = {https://doi.org/10.1038/s41598-020-74710-9}
}

@article{umedakameyama2021-33495415,
  author  = {Umeda-Kameyama, Y. and Kameyama, M. and Tanaka, T. and Son, B. K. and Kojima, T. and Fukasawa, M. and Iizuka, T. and Ogawa, S. and others},
  title   = {{Screening of Alzheimer's disease by facial complexion using artificial intelligence}},
  journal = {Aging},
  year    = {2021},
  doi     = {10.18632/aging.202545},
  pmid    = {33495415},
  url     = {https://doi.org/10.18632/aging.202545}
}

@article{liu2022-36253382,
  author  = {Liu, S. and Masurkar, A. V. and Rusinek, H. and Chen, J. and Zhang, B. and Zhu, W. and Fernandez-Granda, C. and Razavian, N.},
  title   = {{Generalizable deep learning model for early Alzheimer's disease detection from structural MRIs}},
  journal = {Scientific reports},
  year    = {2022},
  doi     = {10.1038/s41598-022-20674-x},
  pmid    = {36253382},
  url     = {https://doi.org/10.1038/s41598-022-20674-x}
}

@article{sleegers2006-16921174,
  author  = {Sleegers, K. and Brouwers, N. and Gijselinck, I. and Theuns, J. and Goossens, D. and Wauters, J. and Del-Favero, J. and Cruts, M. and others},
  title   = {{APP duplication is sufficient to cause early onset Alzheimer's dementia with cerebral amyloid angiopathy}},
  journal = {Brain : a journal of neurology},
  year    = {2006},
  doi     = {10.1093/brain/awl203},
  pmid    = {16921174},
  url     = {https://doi.org/10.1093/brain/awl203}
}

@article{matsumoto2022-35112011,
  author  = {Matsumoto, Hiroshige and Igarashi, Ayumi and Hagiwara, Yasuhiro and Yamamoto‐Mitani, Noriko},
  title   = {{Relational Design for Dementia and Job Significance (ReDeSign): Study protocol for a randomized controlled trial of an online dementia training for retail workers}},
  journal = {Contemporary Clinical Trials Communications},
  year    = {2022},
  doi     = {10.1016/j.conctc.2022.100896},
  pmid    = {35112011},
  url     = {https://doi.org/10.1016/j.conctc.2022.100896}
}

@article{deng2025-39969956,
  author  = {Deng, Cheng and Shen, Na and Li, Guangzhou and Zhang, Ke and Yang, Shijun},
  title   = {{Digital Isolation and Dementia Risk in Older Adults: Longitudinal Cohort Study}},
  journal = {Journal of Medical Internet Research},
  year    = {2025},
  doi     = {10.2196/65379},
  pmid    = {39969956},
  url     = {https://doi.org/10.2196/65379}
}

@article{cavailles2025-40696147,
  author  = {Cavaillès, Clémence and Wallace, Meredith L. and Leng, Yue and Stone, Katie L. and Ancoli‐Israel, Sonia and Yaffe, Kristine S.},
  title   = {{Multidimensional sleep profiles via machine learning and risk of dementia and cardiovascular disease}},
  journal = {Communications Medicine},
  year    = {2025},
  doi     = {10.1038/s43856-025-01019-x},
  pmid    = {40696147},
  url     = {https://doi.org/10.1038/s43856-025-01019-x}
}

@article{ran2026-41717239,
  author  = {Ran, An Ran and Hu, Xiaoyan and Hui, Herbert Y.H. and Dai, Jiajia and Chan, Victor T.T. and Ho, Ko and Au, Lisa WC and Ng, Chak Fung and others},
  title   = {{An Ensemble Learning Artificial Intelligence Model for Alzheimer's Disease Detection Using OCT}},
  journal = {Ophthalmology Science},
  year    = {2026},
  doi     = {10.1016/j.xops.2026.101066},
  pmid    = {41717239},
  url     = {https://doi.org/10.1016/j.xops.2026.101066}
}

@article{li2025-40268961,
  author  = {Li, Juan and Grimes, Kelsey F. and Saade, Joseph and Tomlinson, Julianna J. and Mestre, Tiago and Schade, Sebastian and Weber, Sandrina and Dakna, Mohammed and others},
  title   = {{Development of a simplified smell test to identify Parkinson’s disease using multiple cohorts, machine learning and item response theory}},
  journal = {npj Parkinson s Disease},
  year    = {2025},
  doi     = {10.1038/s41531-025-00904-5},
  pmid    = {40268961},
  url     = {https://doi.org/10.1038/s41531-025-00904-5}
}

@article{jannati2026-42157283,
  author  = {Jannati, Ali and Tobyne, Sean and Pascual-Leone, Alvaro},
  title   = {{Re: Clarifying comparative claims in digital cognitive assessment: Assessing concurrent validity in a shared cohort}},
  journal = {Alzheimer's research \& therapy},
  year    = {2026},
  doi     = {10.1186/s13195-026-01987-9},
  pmid    = {42157283},
  url     = {https://doi.org/10.1186/s13195-026-01987-9}
}

@article{fiske2019-31094356,
  author  = {Fiske, A. and Henningsen, P. and Buyx, A.},
  title   = {{Your Robot Therapist Will See You Now: Ethical Implications of Embodied Artificial Intelligence in Psychiatry, Psychology, and Psychotherapy}},
  journal = {Journal of medical Internet research},
  year    = {2019},
  doi     = {10.2196/13216},
  pmid    = {31094356},
  url     = {https://doi.org/10.2196/13216}
}

@article{zou2024-38431428,
  author  = {Zou, L. and Herold, F. and Cheval, B. and Wheeler, M. J. and Pindus, D. M. and Erickson, K. I. and Raichlen, D. A. and Alexander, G. E. and others},
  title   = {{Sedentary behavior and lifespan brain health}},
  journal = {Trends in cognitive sciences},
  year    = {2024},
  doi     = {10.1016/j.tics.2024.02.003},
  pmid    = {38431428},
  url     = {https://doi.org/10.1016/j.tics.2024.02.003}
}

@article{kavitha2022-35309200,
  author  = {Kavitha, C. and Mani, V. and Srividhya, SR. and Khalaf, O. I. and Tavera Romero, C. A.},
  title   = {{Early-Stage Alzheimer's Disease Prediction Using Machine Learning Models}},
  journal = {Frontiers in public health},
  year    = {2022},
  doi     = {10.3389/fpubh.2022.853294},
  pmid    = {35309200},
  url     = {https://doi.org/10.3389/fpubh.2022.853294}
}

@article{nori2019-31879701,
  author  = {Nori, V. S. and Hane, C. A. and Crown, W. H. and Au, R. and Burke, W. J. and Sanghavi, D. M. and Bleicher, P.},
  title   = {{Machine learning models to predict onset of dementia: A label learning approach}},
  journal = {Alzheimer's \& dementia (New York, N. Y.)},
  year    = {2019},
  doi     = {10.1016/j.trci.2019.10.006},
  pmid    = {31879701},
  url     = {https://doi.org/10.1016/j.trci.2019.10.006}
}

@article{rawtaer2020-32369031,
  author  = {Rawtaer, I. and Mahendran, R. and Kua, E. H. and Tan, H. P. and Tan, H. X. and Lee, T. S. and Ng, T. P.},
  title   = {{Early Detection of Mild Cognitive Impairment With In-Home Sensors to Monitor Behavior Patterns in Community-Dwelling Senior Citizens in Singapore: Cross-Sectional Feasibility Study}},
  journal = {Journal of medical Internet research},
  year    = {2020},
  doi     = {10.2196/16854},
  pmid    = {32369031},
  url     = {https://doi.org/10.2196/16854}
}

@article{jahan2023-37972072,
  author  = {Jahan, S. and Abu Taher, K. and Kaiser, M. S. and Mahmud, M. and Rahman, M. S. and Hosen, A. S. M. S. and Ra, I. H.},
  title   = {{Explainable AI-based Alzheimer's prediction and management using multimodal data}},
  journal = {PloS one},
  year    = {2023},
  doi     = {10.1371/journal.pone.0294253},
  pmid    = {37972072},
  url     = {https://doi.org/10.1371/journal.pone.0294253}
}

@article{leissring2003-14687544,
  author  = {Leissring, M. A. and Farris, W. and Chang, A. Y. and Walsh, D. M. and Wu, X. and Sun, X. and Frosch, M. P. and Selkoe, D. J.},
  title   = {{Enhanced proteolysis of beta-amyloid in APP transgenic mice prevents plaque formation, secondary pathology, and premature death}},
  journal = {Neuron},
  year    = {2003},
  doi     = {10.1016/s0896-6273(03)00787-6},
  pmid    = {14687544},
  url     = {https://doi.org/10.1016/s0896-6273(03)00787-6}
}

@article{lee2024-38806509,
  author  = {Lee, Minwoo and Kim, Hye Weon and Choe, Yeong Sim and Yang, Hyeon Sik and Lee, Jiyeon and Lee, Hyunji and Yong, Jung Hyeon and Kim, Donghyeon and others},
  title   = {{A multimodal machine learning model for predicting dementia conversion in Alzheimer’s disease}},
  journal = {Scientific Reports},
  year    = {2024},
  doi     = {10.1038/s41598-024-60134-2},
  pmid    = {38806509},
  url     = {https://doi.org/10.1038/s41598-024-60134-2}
}

@article{sun2025-b7606922,
  author  = {Sun, Fei and Jiang, Lin Hong and Chen, Xiayu Summer and Feng, Yali},
  title   = {{Interactive AI Technology for Dementia Caregivers: Needs and Implementation Evidence}},
  journal = {Journal of Technology in Human Services},
  year    = {2025},
  doi     = {10.1080/15228835.2025.2460156},
  url     = {https://doi.org/10.1080/15228835.2025.2460156}
}

@article{lin2026-42069499,
  author  = {Lin, Gong‐Hong and Wang, Yi‐Ching and Lee, Shih‐Chieh and Chi, Wen‐Chou and Liu, Jen-Hsuan and Hsieh, Ching‐Lin},
  title   = {{Developing machine learning-enhanced WHODAS 2.0 short forms for persons with dementia}},
  journal = {Journal of the Formosan Medical Association},
  year    = {2026},
  doi     = {10.1016/j.jfma.2026.04.085},
  pmid    = {42069499},
  url     = {https://doi.org/10.1016/j.jfma.2026.04.085}
}

@article{gonzalezprieto2026-41958925,
  author  = {González-Prieto, Cristian and Yelanchezian, Y Mukish M and Dobbie, Gillian and Wilson, Daniel P. and Rodriguez, Claudia Rivera and Oulaghan, Bede and Yates, Susan and Cullum, Sarah J.},
  title   = {{Advancing dementia identification using machine learning and real‐world sequential health data}},
  journal = {Alzheimer s \& Dementia Diagnosis Assessment \& Disease Monitoring},
  year    = {2026},
  doi     = {10.1002/dad2.70332},
  pmid    = {41958925},
  url     = {https://doi.org/10.1002/dad2.70332}
}

@article{hashimoto2025-40369796,
  author  = {Hashimoto, Yuki and Inoue, Norihiko and Tani, Takuaki and Imai, Shinobu},
  title   = {{Machine Learning for Predicting Postoperative Functional Disability and Mortality Among Older Patients With Cancer: Retrospective Cohort Study}},
  journal = {JMIR Aging},
  year    = {2025},
  doi     = {10.2196/65898},
  pmid    = {40369796},
  url     = {https://doi.org/10.2196/65898}
}

@article{laguarta2020-34812418,
  author  = {Laguarta, J. and Hueto, F. and Subirana, B.},
  title   = {{COVID-19 Artificial Intelligence Diagnosis Using Only Cough Recordings}},
  journal = {IEEE open journal of engineering in medicine and biology},
  year    = {2020},
  doi     = {10.1109/ojemb.2020.3026928},
  pmid    = {34812418},
  url     = {https://doi.org/10.1109/ojemb.2020.3026928}
}

@article{huang2019-31213967,
  author  = {Huang, Y. and Xu, J. and Zhou, Y. and Tong, T. and Zhuang, X.},
  title   = {{Diagnosis of Alzheimer's Disease via Multi-Modality 3D Convolutional Neural Network}},
  journal = {Frontiers in neuroscience},
  year    = {2019},
  doi     = {10.3389/fnins.2019.00509},
  pmid    = {31213967},
  url     = {https://doi.org/10.3389/fnins.2019.00509}
}

@article{liu2018-29970996,
  author  = {Liu, M. and Cheng, D. and Yan, W. and {Alzheimer’s Disease Neuroimaging Initiative}},
  title   = {{Classification of Alzheimer's Disease by Combination of Convolutional and Recurrent Neural Networks Using FDG-PET Images}},
  journal = {Frontiers in neuroinformatics},
  year    = {2018},
  doi     = {10.3389/fninf.2018.00035},
  pmid    = {29970996},
  url     = {https://doi.org/10.3389/fninf.2018.00035}
}

@article{hung2024-38527856,
  author  = {Hung, C. and Fertan, E. and Livesey, F. J. and Klenerman, D. and Patani, R.},
  title   = {{APP antisense oligonucleotides reduce amyloid-β aggregation and rescue endolysosomal dysfunction in Alzheimer's disease}},
  journal = {Brain},
  year    = {2024},
  doi     = {10.1093/brain/awae092},
  pmid    = {38527856},
  url     = {https://doi.org/10.1093/brain/awae092}
}

@article{dyrba2013-23741425,
  author  = {Dyrba, M. and Ewers, M. and Wegrzyn, M. and Kilimann, I. and Plant, C. and Oswald, A. and Meindl, T. and Pievani, M. and others},
  title   = {{Robust automated detection of microstructural white matter degeneration in Alzheimer's disease using machine learning classification of multicenter DTI data}},
  journal = {PloS one},
  year    = {2013},
  doi     = {10.1371/journal.pone.0064925},
  pmid    = {23741425},
  url     = {https://doi.org/10.1371/journal.pone.0064925}
}

@article{ibanez2021-34790905,
  author  = {Ibáñez, A. and Pina-Escudero, S. D. and Possin, K. L. and Quiroz, Y. T. and Peres, F. A. and Slachevsky, A. and Sosa, A. L. and Brucki, S. M. D. and others},
  title   = {{Dementia caregiving across Latin America and the Caribbean and brain health diplomacy}},
  journal = {The lancet. Healthy longevity},
  year    = {2021},
  doi     = {10.1016/s2666-7568(21)00031-3},
  pmid    = {34790905},
  url     = {https://doi.org/10.1016/s2666-7568(21)00031-3}
}

@article{oosterhoff2021-34925951,
  author  = {Oosterhoff, J. H. F. and Karhade, A. V. and Oberai, T. and Franco-Garcia, E. and Doornberg, J. N. and Schwab, J. H.},
  title   = {{Prediction of Postoperative Delirium in Geriatric Hip Fracture Patients: A Clinical Prediction Model Using Machine Learning Algorithms}},
  journal = {Geriatric orthopaedic surgery \& rehabilitation},
  year    = {2021},
  doi     = {10.1177/21514593211062277},
  pmid    = {34925951},
  url     = {https://doi.org/10.1177/21514593211062277}
}

@article{zhou2023-37531702,
  author  = {Zhou, Y. and Han, W. and Yao, X. and Xue, J. and Li, Z. and Li, Y.},
  title   = {{Developing a machine learning model for detecting depression, anxiety, and apathy in older adults with mild cognitive impairment using speech and facial expressions: A cross-sectional observational study}},
  journal = {International journal of nursing studies},
  year    = {2023},
  doi     = {10.1016/j.ijnurstu.2023.104562},
  pmid    = {37531702},
  url     = {https://doi.org/10.1016/j.ijnurstu.2023.104562}
}

@article{fowler2025-40300815,
  author  = {Fowler, Nicole R. and Hammers, Dustin B. and Perkins, Anthony J. and Summanwar, Diana and Higbie, Anna and Swartzell, Kristen and Brosch, Jared R. and Willis, Deanna R.},
  title   = {{Feasibility and Acceptability of Implementing a Digital Cognitive Assessment for Alzheimer Disease and Related Dementias in Primary Care}},
  journal = {The Annals of Family Medicine},
  year    = {2025},
  doi     = {10.1370/afm.240293},
  pmid    = {40300815},
  url     = {https://doi.org/10.1370/afm.240293}
}

@article{durrani2025-41441593,
  author  = {Durrani, Faiza Gul and Marshall, Charles R. and Waters, Sheena and Bishop, Lauren and Lim, Dicky G and Smith, Laura Jennie and Chemas, Natalia and Uchegbu, Ijeoma and others},
  title   = {{(DIADEM) Digital Assessment of Auditory Perception in Dementia : Study Protocol}},
  journal = {Alzheimer s \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz70856_098358},
  pmid    = {41441593},
  url     = {https://doi.org/10.1002/alz70856_098358}
}

@article{chien2025-40053718,
  author  = {Chien, Shuo-Chen and Yen, Chia-Ming and Chang, Yu‐Hung and Chen, Ying‐Erh and Liu, Chia-Chun and Hsiao, Yu-Ping and Yang, Ping-Yen and Lin, Hong-Ming and others},
  title   = {{Use of Artificial Intelligence, Internet of Things, and Edge Intelligence in Long-Term Care for Older People: Comprehensive Analysis Through Bibliometric, Google Trends, and Content Analysis}},
  journal = {Journal of Medical Internet Research},
  year    = {2025},
  doi     = {10.2196/56692},
  pmid    = {40053718},
  url     = {https://doi.org/10.2196/56692}
}

@article{jiao2025-40115175,
  author  = {Jiao, Bin and Ouyang, Ziyu and Xiao, Xuewen and Zhang, Cong and Xu, Tianyan and Yang, Qijie and Zhu, Yuan and Liu, Yiliang and others},
  title   = {{Development and validation of machine learning models with blood-based digital biomarkers for Alzheimer’s disease diagnosis: a multicohort diagnostic study}},
  journal = {EClinicalMedicine},
  year    = {2025},
  doi     = {10.1016/j.eclinm.2025.103142},
  pmid    = {40115175},
  url     = {https://doi.org/10.1016/j.eclinm.2025.103142}
}

@article{wang2025-39922598,
  author  = {Wang, Bingsheng and Xie, Ruihan and Qi, Wenhao and Yao, Jiani and Shi, Yankai and Lou, Xiajing and Dong, Chaoqun and Zhu, Xiaohong and others},
  title   = {{Advancing Alzheimer’s disease risk prediction: development and validation of a machine learning-based preclinical screening model in a cross-sectional study}},
  journal = {BMJ Open},
  year    = {2025},
  doi     = {10.1136/bmjopen-2024-092293},
  pmid    = {39922598},
  url     = {https://doi.org/10.1136/bmjopen-2024-092293}
}

@article{chung2025-41220868,
  author  = {Chung, S. S. and Kim, Bori R. and Moon, Sooin and Kim, Geon Ha},
  title   = {{Effects of a 12-Week Hybrid Analog–Digital Cognitive Training on Cognitively Unimpaired Older Adults: A Pilot Single-Blind Randomized Controlled Trial}},
  journal = {Dementia and Neurocognitive Disorders},
  year    = {2025},
  doi     = {10.12779/dnd.2025.24.4.301},
  pmid    = {41220868},
  url     = {https://doi.org/10.12779/dnd.2025.24.4.301}
}

@article{bingke2025-40489822,
  author  = {Bingke, Xing and Jingran, Yang and Hui, Hua and Rong, Jiang},
  title   = {{Rapid health technology assessment of galantamine for the treatment of Alzheimer's disease: A review}},
  journal = {Medicine},
  year    = {2025},
  doi     = {10.1097/MD.0000000000042744},
  pmid    = {40489822},
  url     = {https://doi.org/10.1097/MD.0000000000042744}
}

@article{muurling2021-33892789,
  author  = {Muurling, M. and de Boer, C. and Kozak, R. and Religa, D. and Koychev, I. and Verheij, H. and Nies, V. J. M. and Duyndam, A. and others},
  title   = {{Remote monitoring technologies in Alzheimer's disease: design of the RADAR-AD study}},
  journal = {Alzheimer's research \& therapy},
  year    = {2021},
  doi     = {10.1186/s13195-021-00825-4},
  pmid    = {33892789},
  url     = {https://doi.org/10.1186/s13195-021-00825-4}
}

@article{kalafatis2021-34366938,
  author  = {Kalafatis, C. and Modarres, M. H. and Apostolou, P. and Marefat, H. and Khanbagi, M. and Karimi, H. and Vahabi, Z. and Aarsland, D. and others},
  title   = {{Validity and Cultural Generalisability of a 5-Minute AI-Based, Computerised Cognitive Assessment in Mild Cognitive Impairment and Alzheimer's Dementia}},
  journal = {Frontiers in psychiatry},
  year    = {2021},
  doi     = {10.3389/fpsyt.2021.706695},
  pmid    = {34366938},
  url     = {https://doi.org/10.3389/fpsyt.2021.706695}
}

@article{chan2020-33337341,
  author  = {Chan, J. Y. C. and Wong, A. and Yiu, B. and Mok, H. and Lam, P. and Kwan, P. and Chan, A. and Mok, V. C. T. and others},
  title   = {{Electronic Cognitive Screen Technology for Screening Older Adults With Dementia and Mild Cognitive Impairment in a Community Setting: Development and Validation Study}},
  journal = {Journal of medical Internet research},
  year    = {2020},
  doi     = {10.2196/17332},
  pmid    = {33337341},
  url     = {https://doi.org/10.2196/17332}
}

@article{hajjar2023-36777093,
  author  = {Hajjar, I. and Okafor, M. and Choi, J. D. and Moore, E. and Abrol, A. and Calhoun, V. D. and Goldstein, F. C.},
  title   = {{Development of digital voice biomarkers and associations with cognition, cerebrospinal biomarkers, and neural representation in early Alzheimer's disease}},
  journal = {Alzheimer's \& dementia (Amsterdam, Netherlands)},
  year    = {2023},
  doi     = {10.1002/dad2.12393},
  pmid    = {36777093},
  url     = {https://doi.org/10.1002/dad2.12393}
}

@article{klildrori2024-38558263,
  author  = {Klil-Drori, Sivan and Bodenstein, Katie C and Sun, Shuo and Kojok, Lara and Gruber, Johanna and Ghantous, Youssef and Cummings, Jeffrey and Nasreddine, Ziad},
  title   = {{Montreal Cognitive Assessment (MoCA) XpressO: Validation of a digital self-administered cognitive prescreening tool}},
  journal = {Journal of the American Geriatrics Society},
  year    = {2024},
  doi     = {10.1111/jgs.18902},
  pmid    = {38558263},
  url     = {https://doi.org/10.1111/jgs.18902}
}

@article{deandaduran2024-38226519,
  author  = {De Anda-Duran, Ileana and Sunderaraman, Preeti and Searls, Edward and Moukaled, Shirine and Jin, Xuanyi and Popp, Zachary and Karjadi, Cody and Hwang, Phillip H and others},
  title   = {{Comparing Cognitive Tests and Smartphone-Based Assessment in 2 US Community-Based Cohorts}},
  journal = {Journal of the American Heart Association},
  year    = {2024},
  doi     = {10.1161/jaha.123.032733},
  pmid    = {38226519},
  url     = {https://doi.org/10.1161/jaha.123.032733}
}

@article{barry2023-37620445,
  author  = {Barry, Colin and Wang, Edward},
  title   = {{Racially fair pupillometry measurements for RGB smartphone cameras using the far red spectrum}},
  journal = {Scientific reports},
  year    = {2023},
  doi     = {10.1038/s41598-023-40796-0},
  pmid    = {37620445},
  url     = {https://doi.org/10.1038/s41598-023-40796-0}
}

@article{cho2023-38076544,
  author  = {Cho, Jinju and An, Dayeong and Cho, Eunhye and Kim, Daeun and Choi, Ingyu and Cha, Jihyun and Choi, JongKwan and Na, Duk L and others},
  title   = {{Efficacy of smartphone application-based multi-domain cognitive training in older adults without dementia}},
  journal = {Frontiers in aging neuroscience},
  year    = {2023},
  doi     = {10.3389/fnagi.2023.1250420},
  pmid    = {38076544},
  url     = {https://doi.org/10.3389/fnagi.2023.1250420}
}

@article{kong2024-38423771,
  author  = {Kong, Yu and Guo, Qian Hui and Zhou, Le and He, Liu and Zeng, Yong and Du, Xin and Dong, Jian Zeng and Jiang, Chao and others},
  title   = {{Digital computerised cognitive training for preventing cognitive decline among hypertensive patients: a study protocol for a multicentre randomised controlled trial (DELIGHT trial)}},
  journal = {BMJ open},
  year    = {2024},
  doi     = {10.1136/bmjopen-2023-079305},
  pmid    = {38423771},
  url     = {https://doi.org/10.1136/bmjopen-2023-079305}
}

@article{goodmancasanova2020-32401215,
  author  = {Goodman‐Casanova, Jessica Marian and Dura-Perez, Elena and Parra, Jose Guzman and Cuesta‐Vargas, Antonio and Mayoral, Fermín},
  title   = {{Telehealth Home Support During COVID-19 Confinement for Community-Dwelling Older Adults With Mild Cognitive Impairment or Mild Dementia: Survey Study}},
  journal = {Journal of Medical Internet Research},
  year    = {2020},
  doi     = {10.2196/19434},
  pmid    = {32401215},
  url     = {https://doi.org/10.2196/19434}
}

@article{wu2021-34662373,
  author  = {Wu, X. and Xiao, Z. and Yi, J. and Ding, S. and Gu, H. and Wu, W. and Luo, J. and Liang, X. and others},
  title   = {{Development of a Plasma Biomarker Diagnostic Model Incorporating Ultrasensitive Digital Immunoassay as a Screening Strategy for Alzheimer Disease in a Chinese Population}},
  journal = {Clinical chemistry},
  year    = {2021},
  doi     = {10.1093/clinchem/hvab192},
  pmid    = {34662373},
  url     = {https://doi.org/10.1093/clinchem/hvab192}
}

@article{pera2017-29018038,
  author  = {Pera, M. and Larrea, D. and Guardia-Laguarta, C. and Montesinos, J. and Velasco, K. R. and Agrawal, R. R. and Xu, Y. and Chan, R. B. and others},
  title   = {{Increased localization of APP-C99 in mitochondria-associated ER membranes causes mitochondrial dysfunction in Alzheimer disease}},
  journal = {The EMBO journal},
  year    = {2017},
  doi     = {10.15252/embj.201796797},
  pmid    = {29018038},
  url     = {https://doi.org/10.15252/embj.201796797}
}

@article{zucchella2018-30619031,
  author  = {Zucchella, C. and Sinforiani, E. and Tamburin, S. and Federico, A. and Mantovani, E. and Bernini, S. and Casale, R. and Bartolo, M.},
  title   = {{The Multidisciplinary Approach to Alzheimer's Disease and Dementia. A Narrative Review of Non-Pharmacological Treatment}},
  journal = {Frontiers in neurology},
  year    = {2018},
  doi     = {10.3389/fneur.2018.01058},
  pmid    = {30619031},
  url     = {https://doi.org/10.3389/fneur.2018.01058}
}

@article{pellegrini2018-30364671,
  author  = {Pellegrini, E. and Ballerini, L. and Hernandez, M. D. C. V. and Chappell, F. M. and González-Castro, V. and Anblagan, D. and Danso, S. and Muñoz-Maniega, S. and others},
  title   = {{Machine learning of neuroimaging for assisted diagnosis of cognitive impairment and dementia: A systematic review}},
  journal = {Alzheimer's \& dementia (Amsterdam, Netherlands)},
  year    = {2018},
  doi     = {10.1016/j.dadm.2018.07.004},
  pmid    = {30364671},
  url     = {https://doi.org/10.1016/j.dadm.2018.07.004}
}

@article{gold2018-29955666,
  author  = {Gold, M. and Amatniek, J. and Carrillo, M. C. and Cedarbaum, J. M. and Hendrix, J. A. and Miller, B. B. and Robillard, J. M. and Rice, J. J. and others},
  title   = {{Digital technologies as biomarkers, clinical outcomes assessment, and recruitment tools in Alzheimer's disease clinical trials}},
  journal = {Alzheimer's \& dementia (New York, N. Y.)},
  year    = {2018},
  doi     = {10.1016/j.trci.2018.04.003},
  pmid    = {29955666},
  url     = {https://doi.org/10.1016/j.trci.2018.04.003}
}

@article{mosadeghi2016-27349654,
  author  = {Mosadeghi, S. and Reid, M. W. and Martinez, B. and Rosen, B. T. and Spiegel, B. M.},
  title   = {{Feasibility of an Immersive Virtual Reality Intervention for Hospitalized Patients: An Observational Cohort Study}},
  journal = {JMIR mental health},
  year    = {2016},
  doi     = {10.2196/mental.5801},
  pmid    = {27349654},
  url     = {https://doi.org/10.2196/mental.5801}
}

@article{liu2018-29352978,
  author  = {Liu, X. and Chen, K. and Wu, T. and Weidman, D. and Lure, F. and Li, J.},
  title   = {{Use of multimodality imaging and artificial intelligence for diagnosis and prognosis of early stages of Alzheimer's disease}},
  journal = {Translational research : the journal of laboratory and clinical medicine},
  year    = {2018},
  doi     = {10.1016/j.trsl.2018.01.001},
  pmid    = {29352978},
  url     = {https://doi.org/10.1016/j.trsl.2018.01.001}
}

@article{ranson2021-34635138,
  author  = {Ranson, J. M. and Rittman, T. and Hayat, S. and Brayne, C. and Jessen, F. and Blennow, K. and van Duijn, C. and Barkhof, F. and others},
  title   = {{Modifiable risk factors for dementia and dementia risk profiling. A user manual for Brain Health Services-part 2 of 6}},
  journal = {Alzheimer's research \& therapy},
  year    = {2021},
  doi     = {10.1186/s13195-021-00895-4},
  pmid    = {34635138},
  url     = {https://doi.org/10.1186/s13195-021-00895-4}
}

@article{grassi2019-31379711,
  author  = {Grassi, M. and Rouleaux, N. and Caldirola, D. and Loewenstein, D. and Schruers, K. and Perna, G. and Dumontier, M. and {Alzheimer's Disease Neuroimaging Initiative}},
  title   = {{A Novel Ensemble-Based Machine Learning Algorithm to Predict the Conversion From Mild Cognitive Impairment to Alzheimer's Disease Using Socio-Demographic Characteristics, Clinical Information, and Neuropsychological Measures}},
  journal = {Frontiers in neurology},
  year    = {2019},
  doi     = {10.3389/fneur.2019.00756},
  pmid    = {31379711},
  url     = {https://doi.org/10.3389/fneur.2019.00756}
}

@article{mcardle2020-31901765,
  author  = {Mc Ardle, R. and Del Din, S. and Galna, B. and Thomas, A. and Rochester, L.},
  title   = {{Differentiating dementia disease subtypes with gait analysis: feasibility of wearable sensors?}},
  journal = {Gait \& posture},
  year    = {2020},
  doi     = {10.1016/j.gaitpost.2019.12.028},
  pmid    = {31901765},
  url     = {https://doi.org/10.1016/j.gaitpost.2019.12.028}
}

@article{tian2021-33420208,
  author  = {Tian, J. and Smith, G. and Guo, H. and Liu, B. and Pan, Z. and Wang, Z. and Xiong, S. and Fang, R.},
  title   = {{Modular machine learning for Alzheimer's disease classification from retinal vasculature}},
  journal = {Scientific reports},
  year    = {2021},
  doi     = {10.1038/s41598-020-80312-2},
  pmid    = {33420208},
  url     = {https://doi.org/10.1038/s41598-020-80312-2}
}

@article{arighi2021-33459891,
  author  = {Arighi, A. and Fumagalli, G. G. and Carandini, T. and Pietroboni, A. M. and De Riz, M. A. and Galimberti, D. and Scarpini, E.},
  title   = {{Facing the digital divide into a dementia clinic during COVID-19 pandemic: caregiver age matters}},
  journal = {Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology},
  year    = {2021},
  doi     = {10.1007/s10072-020-05009-w},
  pmid    = {33459891},
  url     = {https://doi.org/10.1007/s10072-020-05009-w}
}

@article{muller2017-28443019,
  author  = {Müller, S. and Preische, O. and Heymann, P. and Elbing, U. and Laske, C.},
  title   = {{Increased Diagnostic Accuracy of Digital vs. Conventional Clock Drawing Test for Discrimination of Patients in the Early Course of Alzheimer's Disease from Cognitively Healthy Individuals}},
  journal = {Frontiers in aging neuroscience},
  year    = {2017},
  doi     = {10.3389/fnagi.2017.00101},
  pmid    = {28443019},
  url     = {https://doi.org/10.3389/fnagi.2017.00101}
}

@article{birkenbihl2020-32843907,
  author  = {Birkenbihl, C. and Emon, M. A. and Vrooman, H. and Westwood, S. and Lovestone, S. and {AddNeuroMed Consortium} and Hofmann-Apitius, M. and Fröhlich, H. and others},
  title   = {{Differences in cohort study data affect external validation of artificial intelligence models for predictive diagnostics of dementia - lessons for translation into clinical practice}},
  journal = {The EPMA journal},
  year    = {2020},
  doi     = {10.1007/s13167-020-00216-z},
  pmid    = {32843907},
  url     = {https://doi.org/10.1007/s13167-020-00216-z}
}

@article{folego2020-33195111,
  author  = {Folego, G. and Weiler, M. and Casseb, R. F. and Pires, R. and Rocha, A.},
  title   = {{Alzheimer's Disease Detection Through Whole-Brain 3D-CNN MRI}},
  journal = {Frontiers in bioengineering and biotechnology},
  year    = {2020},
  doi     = {10.3389/fbioe.2020.534592},
  pmid    = {33195111},
  url     = {https://doi.org/10.3389/fbioe.2020.534592}
}

@article{alsaeed2022-35458896,
  author  = {AlSaeed, D. and Omar, S. F.},
  title   = {{Brain MRI Analysis for Alzheimer's Disease Diagnosis Using CNN-Based Feature Extraction and Machine Learning}},
  journal = {Sensors (Basel, Switzerland)},
  year    = {2022},
  doi     = {10.3390/s22082911},
  pmid    = {35458896},
  url     = {https://doi.org/10.3390/s22082911}
}

@article{alamro2023-36973386,
  author  = {Alamro, H. and Thafar, M. A. and Albaradei, S. and Gojobori, T. and Essack, M. and Gao, X.},
  title   = {{Exploiting machine learning models to identify novel Alzheimer's disease biomarkers and potential targets}},
  journal = {Scientific reports},
  year    = {2023},
  doi     = {10.1038/s41598-023-30904-5},
  pmid    = {36973386},
  url     = {https://doi.org/10.1038/s41598-023-30904-5}
}

@article{olsson2005-15563479,
  author  = {Olsson, A. and Vanderstichele, H. and Andreasen, N. and De Meyer, G. and Wallin, A. and Holmberg, B. and Rosengren, L. and Vanmechelen, E. and others},
  title   = {{Simultaneous measurement of beta-amyloid(1-42), total tau, and phosphorylated tau (Thr181) in cerebrospinal fluid by the xMAP technology}},
  journal = {Clinical chemistry},
  year    = {2005},
  doi     = {10.1373/clinchem.2004.039347},
  pmid    = {15563479},
  url     = {https://doi.org/10.1373/clinchem.2004.039347}
}

@article{khalfallah2025-290cd850,
  author  = {Khalfallah, Souhaila and Puech, William and Tlija, Mehdi and Bouallegue, Kais},
  title   = {{Exploring the Effectiveness of Machine Learning and Deep Learning Techniques for EEG Signal Classification in Neurological Disorders}},
  journal = {IEEE Access},
  year    = {2025},
  doi     = {10.1109/access.2025.3532515},
  url     = {https://doi.org/10.1109/access.2025.3532515}
}

@article{yan2025-40927874,
  author  = {Yan, Min and Zhou, Hongyu and Li, Zixiao and Wang, Yongjun},
  title   = {{Retinal biomarkers in cognitive impairment and dementia: Structural, functional, and molecular insights}},
  journal = {Alzheimer s \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz.70672},
  pmid    = {40927874},
  url     = {https://doi.org/10.1002/alz.70672}
}

@article{jasodanand2025-40983947,
  author  = {Jasodanand, Varuna H. and Bellitti, Matteo and Kolachalama, Vijaya B.},
  title   = {{An AI‐first framework for multimodal data in Alzheimer's disease and related dementias}},
  journal = {Alzheimer s \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz.70719},
  pmid    = {40983947},
  url     = {https://doi.org/10.1002/alz.70719}
}

@article{gramkow2025-40399918,
  author  = {Gramkow, Mathias Holsey and Brink-Kjær, Andreas and Clemmensen, Frederikke Kragh and Sjælland, Nikolai Sulkjær and Waldemar, Gunhild and Jennum, Poul and Hasselbalch, Steen Gregers and Frederiksen, Kristian Steen},
  title   = {{Diagnostic performance of actigraphy in Alzheimer’s disease using a machine learning classifier – a cross-sectional memory clinic study}},
  journal = {Alzheimer s Research \& Therapy},
  year    = {2025},
  doi     = {10.1186/s13195-025-01751-5},
  pmid    = {40399918},
  url     = {https://doi.org/10.1186/s13195-025-01751-5}
}

@article{mieling2025-40285975,
  author  = {Mieling, Marthe and Yousuf, Mushfa and Bunzeck, Nico and {Alzheimer’s Disease Neuroimaging Initiative} and Weiner, Michael and Aisen, Paul and Petersen, Ronald and Jack, Clifford R. and others},
  title   = {{Predicting the progression of MCI and Alzheimer’s disease on structural brain integrity and other features with machine learning}},
  journal = {GeroScience},
  year    = {2025},
  doi     = {10.1007/s11357-025-01626-5},
  pmid    = {40285975},
  url     = {https://doi.org/10.1007/s11357-025-01626-5}
}

@article{chen2026-41734929,
  author  = {Chen, Yong-chuan and Nieh, Hsiao‐Chi and Chen, Hsiao-Chu and Chen, Jung-Chih and Chang, Mei‐Yu and Wu, Pi-O},
  title   = {{Generative artificial intelligence in dementia care: a scoping review protocol on nursing roles, experiences and ethical perspectives}},
  journal = {BMJ Open},
  year    = {2026},
  doi     = {10.1136/bmjopen-2025-114064},
  pmid    = {41734929},
  url     = {https://doi.org/10.1136/bmjopen-2025-114064}
}

@article{alaka2025-41434961,
  author  = {Alaka, Shakiru A. and Ngan, SoFong Cam and MacPherson, Rebecca E. K. and Pickett, William and Chen, Christopher and Sze, Newman},
  title   = {{Enhancing Dementia Risk Prediction with Heart Rate and Machine Learning in the Canadian Longitudinal Study on Aging (CLSA)}},
  journal = {Alzheimer s \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz70860_098393},
  pmid    = {41434961},
  url     = {https://doi.org/10.1002/alz70860_098393}
}

@article{wu2025-41460179,
  author  = {Wu, Kuan-Ching and Belza, Basia L. and Berry, Donna Lynn and Lewis, Frances Marcus and Hartzler, Andrea L. and Zaslavsky, Oleg},
  title   = {{Digital health interventions for urinary tract infection prevention and management in people living with dementia and their family caregivers: a scoping review}},
  journal = {The Gerontologist},
  year    = {2025},
  doi     = {10.1093/geront/gnaf268},
  pmid    = {41460179},
  url     = {https://doi.org/10.1093/geront/gnaf268}
}

@article{xu2025-40707547,
  author  = {Xu, Jing and Zhang, Wenjin and Liu, Wenli},
  title   = {{A machine learning-based approach to predict depression in Chinese older adults with subjective cognitive decline: a longitudinal study}},
  journal = {Scientific Reports},
  year    = {2025},
  doi     = {10.1038/s41598-025-10645-3},
  pmid    = {40707547},
  url     = {https://doi.org/10.1038/s41598-025-10645-3}
}

@article{tlemcani2025-41004471,
  author  = {Tlemçani, Fatima Zahra Rhmari and Aitlahbib, Faiçal and Laidi, Soukaina and Idrissi, Najib Al and Aasfara, Jehanne and Elamari, Saloua and Chadli, Asma and Motaib, Imane},
  title   = {{Diabetic retinopathy as the primary predictor of mild cognitive impairment in type 2 diabetes: Insights from machine learning models}},
  journal = {PLoS ONE},
  year    = {2025},
  doi     = {10.1371/journal.pone.0332442},
  pmid    = {41004471},
  url     = {https://doi.org/10.1371/journal.pone.0332442}
}

@article{abdelhameed2025-41049748,
  author  = {Abdelhameed, Ahmed M. and Feng, Jingna and Hu, Xinyue and Li, Fang and Lundin, Sori Kim and Schulz, Paul Ernest and Tao, Cui},
  title   = {{AI-powered model for accurate prediction of MCI-to-AD progression}},
  journal = {Acta Pharmaceutica Sinica B},
  year    = {2025},
  doi     = {10.1016/j.apsb.2025.01.027},
  pmid    = {41049748},
  url     = {https://doi.org/10.1016/j.apsb.2025.01.027}
}

@article{rachael2025-42712339,
  author  = {Rachael, Brooks and Hoevenaar-Blom Marieke, P. and Nicola, Coley and Moll van Charante Eric, P. and Linda, Barnes and Edo, Richard and Carol, Brayne},
  title   = {{Smartphone barrier: uncovering the digital divide in mHealth prevention among disadvantaged middle-aged and older-aged UK communities}},
  journal = {BMJ digital health \& AI},
  year    = {2025},
  doi     = {10.1136/bmjdhai-2025-000069},
  pmid    = {42712339},
  url     = {https://doi.org/10.1136/bmjdhai-2025-000069}
}

@article{wagner2020-32704412,
  author  = {Wagner, S. K. and Fu, D. J. and Faes, L. and Liu, X. and Huemer, J. and Khalid, H. and Ferraz, D. and Korot, E. and others},
  title   = {{Insights into Systemic Disease through Retinal Imaging-Based Oculomics}},
  journal = {Translational vision science \& technology},
  year    = {2020},
  doi     = {10.1167/tvst.9.2.6},
  pmid    = {32704412},
  url     = {https://doi.org/10.1167/tvst.9.2.6}
}

@article{diniz2015-25092249,
  author  = {Diniz, B. S. and Sibille, E. and Ding, Y. and Tseng, G. and Aizenstein, H. J. and Lotrich, F. and Becker, J. T. and Lopez, O. L. and others},
  title   = {{Plasma biosignature and brain pathology related to persistent cognitive impairment in late-life depression}},
  journal = {Molecular psychiatry},
  year    = {2015},
  doi     = {10.1038/mp.2014.76},
  pmid    = {25092249},
  url     = {https://doi.org/10.1038/mp.2014.76}
}

@article{mihailidis2008-18992135,
  author  = {Mihailidis, A. and Boger, J. N. and Craig, T. and Hoey, J.},
  title   = {{The COACH prompting system to assist older adults with dementia through handwashing: an efficacy study}},
  journal = {BMC geriatrics},
  year    = {2008},
  doi     = {10.1186/1471-2318-8-28},
  pmid    = {18992135},
  url     = {https://doi.org/10.1186/1471-2318-8-28}
}

@article{cheng2024-38382465,
  author  = {Cheng, F. and Wang, F. and Tang, J. and Zhou, Y. and Fu, Z. and Zhang, P. and Haines, J. L. and Leverenz, J. B. and others},
  title   = {{Artificial intelligence and open science in discovery of disease-modifying medicines for Alzheimer's disease}},
  journal = {Cell reports. Medicine},
  year    = {2024},
  doi     = {10.1016/j.xcrm.2023.101379},
  pmid    = {38382465},
  url     = {https://doi.org/10.1016/j.xcrm.2023.101379}
}

@article{mcardle2018-29614664,
  author  = {Mc Ardle, R. and Morris, R. and Hickey, A. and Del Din, S. and Koychev, I. and Gunn, R. N. and Lawson, J. and Zamboni, G. and others},
  title   = {{Gait in Mild Alzheimer's Disease: Feasibility of Multi-Center Measurement in the Clinic and Home with Body-Worn Sensors: A Pilot Study}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2018},
  doi     = {10.3233/jad-171116},
  pmid    = {29614664},
  url     = {https://doi.org/10.3233/jad-171116}
}

@article{davoudi2021-34219737,
  author  = {Davoudi, A. and Dion, C. and Amini, S. and Tighe, P. J. and Price, C. C. and Libon, D. J. and Rashidi, P.},
  title   = {{Classifying Non-Dementia and Alzheimer's Disease/Vascular Dementia Patients Using Kinematic, Time-Based, and Visuospatial Parameters: The Digital Clock Drawing Test}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2021},
  doi     = {10.3233/jad-201129},
  pmid    = {34219737},
  url     = {https://doi.org/10.3233/jad-201129}
}

@article{im2023-37494443,
  author  = {Im, E. and Jiang, Y. and Stavrides, P. H. and Darji, S. and Erdjument-Bromage, H. and Neubert, T. A. and Choi, J. Y. and Wegiel, J. and others},
  title   = {{Lysosomal dysfunction in Down syndrome and Alzheimer mouse models is caused by v-ATPase inhibition by Tyr682-phosphorylated APP βCTF}},
  journal = {Science advances},
  year    = {2023},
  doi     = {10.1126/sciadv.adg1925},
  pmid    = {37494443},
  url     = {https://doi.org/10.1126/sciadv.adg1925}
}

@article{bhattacharjee2016-26949937,
  author  = {Bhattacharjee, S. and Zhao, Y. and Dua, P. and Rogaev, E. I. and Lukiw, W. J.},
  title   = {{microRNA-34a-Mediated Down-Regulation of the Microglial-Enriched Triggering Receptor and Phagocytosis-Sensor TREM2 in Age-Related Macular Degeneration}},
  journal = {PloS one},
  year    = {2016},
  doi     = {10.1371/journal.pone.0150211},
  pmid    = {26949937},
  url     = {https://doi.org/10.1371/journal.pone.0150211}
}

@article{valentisoler2015-26388764,
  author  = {Valentí Soler, M. and Agüera-Ortiz, L. and Olazarán Rodríguez, J. and Mendoza Rebolledo, C. and Pérez Muñoz, A. and Rodríguez Pérez, I. and Osa Ruiz, E. and Barrios Sánchez, A. and others},
  title   = {{Social robots in advanced dementia}},
  journal = {Frontiers in aging neuroscience},
  year    = {2015},
  doi     = {10.3389/fnagi.2015.00133},
  pmid    = {26388764},
  url     = {https://doi.org/10.3389/fnagi.2015.00133}
}

@article{yoo2025-40935607,
  author  = {Yoo, Hye Bin and Kang, Seung Kwan and Shin, Seong Ah and Kim, Daewoon and Choi, Hongyoon and Kim, Yoon‐Keun and Yi, Dahyun and Byun, Min Soo and others},
  title   = {{Artificial Intelligence–Powered Quantification of Flortaucipir PET for Detecting Tau Pathology}},
  journal = {Journal of Nuclear Medicine},
  year    = {2025},
  doi     = {10.2967/jnumed.125.269636},
  pmid    = {40935607},
  url     = {https://doi.org/10.2967/jnumed.125.269636}
}

@article{matsuda2025-40406128,
  author  = {Matsuda, Kazuki Mitsuru and Umeda‐Kameyama, Yumi and Iwadoh, Kazuhiro and Miyawaki, Masashi and Yakabe, Mitsutaka and Ishii, Masaki and Ogawa, Sumito and Akishita, Masahiro and others},
  title   = {{Artificial intelligence and omics-based autoantibody profiling in dementia}},
  journal = {Frontiers in Immunology},
  year    = {2025},
  doi     = {10.3389/fimmu.2025.1537659},
  pmid    = {40406128},
  url     = {https://doi.org/10.3389/fimmu.2025.1537659}
}

@article{hasan2025-40634226,
  author  = {Hasan, Zain and Shum, Leia C and Faruk, Tamim and McGilton, Katherine S. and Chu, Charlene H. and McArthur, Caitlin and Flint, Alastair J. and Mihailidis, Alex and others},
  title   = {{Machine Learning to Detect Motor Agitation in People With Dementia Using Real-Time Location Data}},
  journal = {American Journal of Geriatric Psychiatry},
  year    = {2025},
  doi     = {10.1016/j.jagp.2025.06.001},
  pmid    = {40634226},
  url     = {https://doi.org/10.1016/j.jagp.2025.06.001}
}

@article{martinezthompson2025-39820267,
  author  = {Martinez‐Thompson, Jennifer M. and Mazurek, Kevin A. and Cantu, Carolina Parra and Naddaf, Elie and Gogineni, Venkatsampath and Botha, Hugo and Jones, David Thomas and Laughlin, Ruple S. and others},
  title   = {{Artificial intelligence models using F-wave responses predict amyotrophic lateral sclerosis}},
  journal = {Brain},
  year    = {2025},
  doi     = {10.1093/brain/awaf014},
  pmid    = {39820267},
  url     = {https://doi.org/10.1093/brain/awaf014}
}

@article{stern2025-40864401,
  author  = {Stern, Amos and Linial, Michal},
  title   = {{Integrative machine learning approach to risk prediction for dementia and Alzheimer’s disease}},
  journal = {GeroScience},
  year    = {2025},
  doi     = {10.1007/s11357-025-01828-x},
  pmid    = {40864401},
  url     = {https://doi.org/10.1007/s11357-025-01828-x}
}

@article{tsiakiri2025-41471663,
  author  = {Tsiakiri, Anna and Plakias, Spyridon and Giarmatzis, Georgios and Tsakni, Georgia J. and Christidi, Foteini and Karakitsiou, Georgia and Georgousopoulou, Vasiliki and Manomenidis, Georgios and others},
  title   = {{Wearable Sensor Technologies and Gait Analysis for Early Detection of Dementia: Trends and Future Directions}},
  journal = {Sensors},
  year    = {2025},
  doi     = {10.3390/s25247669},
  pmid    = {41471663},
  url     = {https://doi.org/10.3390/s25247669}
}

@article{ghiasi2026-42149898,
  author  = {Ghiasi, Mohammad Mahdi and Falck, Ryan S. and Liu-Ambrose, Teresa Y L and Tam, Roger C},
  title   = {{Explainable machine learning for predicting longitudinal dementia status: Establishing a leakage-free benchmark}},
  journal = {PLOS Digital Health},
  year    = {2026},
  doi     = {10.1371/journal.pdig.0001409},
  pmid    = {42149898},
  url     = {https://doi.org/10.1371/journal.pdig.0001409}
}

@article{choi2025-40594040,
  author  = {Choi, Dong Hyeok and Ahn, So Hyun and Chung, Yujin and Kim, Jin Sung and Jeong, Jee Hyang and Yoon, Hai‐Jeon},
  title   = {{Machine learning model for predicting Amyloid-β positivity and cognitive status using early-phase 18F-Florbetaben PET and clinical features}},
  journal = {Scientific Reports},
  year    = {2025},
  doi     = {10.1038/s41598-025-00743-7},
  pmid    = {40594040},
  url     = {https://doi.org/10.1038/s41598-025-00743-7}
}

@article{bertram2026-42286243,
  author  = {Bertram, David and Ophey, Anja and Röttgen, Sinah and Kufer, Konstantin and Merten, Nele and Fink, Gereon R. and Kalbe, Elke and Hansen, Clint and others},
  title   = {{ActiTect: a generalizable machine learning pipeline for REM sleep behavior disorder screening through standardized actigraphy}},
  journal = {npj Digital Medicine},
  year    = {2026},
  doi     = {10.1038/s41746-026-02738-8},
  pmid    = {42286243},
  url     = {https://doi.org/10.1038/s41746-026-02738-8}
}

@article{boppana2025-40471913,
  author  = {Boppana, Sri Harsha and Tyagi, Divyansh and Komati, Sachin Sravan Kumar and Boppana, Sri Lasya and Raj, Ritwik and Mintz, Cyrus David},
  title   = {{AI-delirium guard: Predictive modeling of postoperative delirium in elderly surgical patients}},
  journal = {PLoS ONE},
  year    = {2025},
  doi     = {10.1371/journal.pone.0322032},
  pmid    = {40471913},
  url     = {https://doi.org/10.1371/journal.pone.0322032}
}

@article{kangas2014-25138139,
  author  = {Kangas, Maarit and Korpelainen, Raija and Vikman, Irene and Nyberg, Lars H and Jämsä, Timo J.},
  title   = {{Sensitivity and False Alarm Rate of a Fall Sensor in Long-Term Fall Detection in the Elderly}},
  journal = {Gerontology},
  year    = {2014},
  doi     = {10.1159/000362720},
  pmid    = {25138139},
  url     = {https://doi.org/10.1159/000362720}
}

@article{nicosia2023-36062528,
  author  = {Nicosia, J. and Aschenbrenner, A. J. and Balota, D. A. and Sliwinski, M. J. and Tahan, M. and Adams, S. and Stout, S. S. and Wilks, H. and others},
  title   = {{Unsupervised high-frequency smartphone-based cognitive assessments are reliable, valid, and feasible in older adults at risk for Alzheimer's disease}},
  journal = {Journal of the International Neuropsychological Society : JINS},
  year    = {2023},
  doi     = {10.1017/s135561772200042x},
  pmid    = {36062528},
  url     = {https://doi.org/10.1017/s135561772200042x}
}

@article{jongstra2017-28546139,
  author  = {Jongstra, S. and Wijsman, L. W. and Cachucho, R. and Hoevenaar-Blom, M. P. and Mooijaart, S. P. and Richard, E.},
  title   = {{Cognitive Testing in People at Increased Risk of Dementia Using a Smartphone App: The iVitality Proof-of-Principle Study}},
  journal = {JMIR mHealth and uHealth},
  year    = {2017},
  doi     = {10.2196/mhealth.6939},
  pmid    = {28546139},
  url     = {https://doi.org/10.2196/mhealth.6939}
}

@article{robin2021-34778869,
  author  = {Robin, J. and Xu, M. and Kaufman, L. D. and Simpson, W.},
  title   = {{Using Digital Speech Assessments to Detect Early Signs of Cognitive Impairment}},
  journal = {Frontiers in digital health},
  year    = {2021},
  doi     = {10.3389/fdgth.2021.749758},
  pmid    = {34778869},
  url     = {https://doi.org/10.3389/fdgth.2021.749758}
}

@article{fox2022-35029539,
  author  = {Fox, S. and Brown, L. J. E. and Antrobus, S. and Brough, D. and Drake, R. J. and Jury, F. and Leroi, I. and Parry-Jones, A. R. and others},
  title   = {{Co-design of a Smartphone App for People Living With Dementia by Applying Agile, Iterative Co-design Principles: Development and Usability Study}},
  journal = {JMIR mHealth and uHealth},
  year    = {2022},
  doi     = {10.2196/24483},
  pmid    = {35029539},
  url     = {https://doi.org/10.2196/24483}
}

@article{ye2022-35436212,
  author  = {Ye, S. and Sun, K. and Huynh, D. and Phi, H. Q. and Ko, B. and Huang, B. and Hosseini Ghomi, R.},
  title   = {{A Computerized Cognitive Test Battery for Detection of Dementia and Mild Cognitive Impairment: Instrument Validation Study}},
  journal = {JMIR aging},
  year    = {2022},
  doi     = {10.2196/36825},
  pmid    = {35436212},
  url     = {https://doi.org/10.2196/36825}
}

@article{goodridge2021-34842530,
  author  = {Goodridge, D. and Reis, N. and Neiser, J. and Haubrich, T. and Westberg, B. and Erickson-Lumb, L. and Storozinski, J. and Gonzales, C. and others},
  title   = {{An App-Based Mindfulness-Based Self-compassion Program to Support Caregivers of People With Dementia: Participatory Feasibility Study}},
  journal = {JMIR aging},
  year    = {2021},
  doi     = {10.2196/28652},
  pmid    = {34842530},
  url     = {https://doi.org/10.2196/28652}
}

@article{liu2018-29572601,
  author  = {Liu, M. and Cheng, D. and Wang, K. and Wang, Y. and {Alzheimer’s Disease Neuroimaging Initiative}},
  title   = {{Multi-Modality Cascaded Convolutional Neural Networks for Alzheimer's Disease Diagnosis}},
  journal = {Neuroinformatics},
  year    = {2018},
  doi     = {10.1007/s12021-018-9370-4},
  pmid    = {29572601},
  url     = {https://doi.org/10.1007/s12021-018-9370-4}
}

@article{gao2017-27886714,
  author  = {Gao, X. W. and Hui, R. and Tian, Z.},
  title   = {{Classification of CT brain images based on deep learning networks}},
  journal = {Computer methods and programs in biomedicine},
  year    = {2017},
  doi     = {10.1016/j.cmpb.2016.10.007},
  pmid    = {27886714},
  url     = {https://doi.org/10.1016/j.cmpb.2016.10.007}
}

@article{ohman2022-36426215,
  author  = {Öhman, Fredrik and Berron, David and Papp, Kathryn V and Kern, Silke and Skoog, Johan and Bodin, Timothy Hadarsson and Zettergren, Anna and Skoog, Ingmar and others},
  title   = {{Unsupervised mobile app-based cognitive testing in a population-based study of older adults born 1944}},
  journal = {Frontiers in digital health},
  year    = {2022},
  doi     = {10.3389/fdgth.2022.933265},
  pmid    = {36426215},
  url     = {https://doi.org/10.3389/fdgth.2022.933265}
}

@article{blotenberg2025-39946414,
  author  = {Blotenberg, Iris and Boekholt, Melanie and Lieberknecht, Nils and Säring, Paula and Thyrian, Jochen René},
  title   = {{Acceptance of Unsupervised App-Based Cognitive Assessment in Outpatient Care: An Implementation Study}},
  journal = {JMIR formative research},
  year    = {2025},
  doi     = {10.2196/62706},
  pmid    = {39946414},
  url     = {https://doi.org/10.2196/62706}
}

@article{edwards2021-33817548,
  author  = {Edwards, Jerri D and Philllips, Christine B and O'Connor, Melissa L and O'Brien, Jennifer L and Hudak, Elizabeth M and Nicholson, Jody S},
  title   = {{Applying the Health Belief Model to Quantify and Investigate Expectations for Computerized Cognitive Training}},
  journal = {Journal of cognitive enhancement : towards the integration of theory and practice},
  year    = {2021},
  doi     = {10.1007/s41465-020-00183-3},
  pmid    = {33817548},
  url     = {https://doi.org/10.1007/s41465-020-00183-3}
}

@article{park2025-41068341,
  author  = {Park, Ingyu and Lee, Sang-Kyu and Choi, Hui-Chul and Ahn, Moo-Eob and Ryu, Ohk-Hyun and Park, Yong Soon and Kim, Dong-Kyu and Lee, Unjoo and others},
  title   = {{Machine learning-based estimation of the mild cognitive impairment stage using multimodal physical and behavioral measures}},
  journal = {Scientific reports},
  year    = {2025},
  doi     = {10.1038/s41598-025-19364-1},
  pmid    = {41068341},
  url     = {https://doi.org/10.1038/s41598-025-19364-1}
}

@article{butler2024-38269369,
  author  = {Butler, Joe and Watermeyer, Tamlyn J and Matterson, Ellie and Harper, Emily G and Parra-Rodriguez, Mario},
  title   = {{The development and validation of a digital biomarker for remote assessment of Alzheimer's diseases risk}},
  journal = {Digital health},
  year    = {2024},
  doi     = {10.1177/20552076241228416},
  pmid    = {38269369},
  url     = {https://doi.org/10.1177/20552076241228416}
}

@article{book2022-35513855,
  author  = {Book, Stephanie and Jank, Michael and Pendergrass, Anna and Graessel, Elmar},
  title   = {{Individualised computerised cognitive training for community-dwelling people with mild cognitive impairment: study protocol of a completely virtual, randomised, controlled trial}},
  journal = {Trials},
  year    = {2022},
  doi     = {10.1186/s13063-022-06152-9},
  pmid    = {35513855},
  url     = {https://doi.org/10.1186/s13063-022-06152-9}
}

@article{zhao2022-35935417,
  author  = {Zhao, Xuhao and Hu, Ruofei and Wen, Haoxuan and Xu, Guohai and Pang, Ting and He, Xindi and Zhang, Yaping and Zhang, Ji and others},
  title   = {{A voice recognition-based digital cognitive screener for dementia detection in the community: Development and validation study}},
  journal = {Frontiers in psychiatry},
  year    = {2022},
  doi     = {10.3389/fpsyt.2022.899729},
  pmid    = {35935417},
  url     = {https://doi.org/10.3389/fpsyt.2022.899729}
}

@article{thompson2023-38026761,
  author  = {Thompson, Louisa I and Kunicki, Zachary J and Emrani, Sheina and Strenger, Jennifer and De Vito, Alyssa N and Britton, Karysa J and Dion, Catherine and Harrington, Karra D and others},
  title   = {{Remote and in-clinic digital cognitive screening tools outperform the MoCA to distinguish cerebral amyloid status among cognitively healthy older adults}},
  journal = {Alzheimer's \& dementia (Amsterdam, Netherlands)},
  year    = {2023},
  doi     = {10.1002/dad2.12500},
  pmid    = {38026761},
  url     = {https://doi.org/10.1002/dad2.12500}
}

@article{ghose2024-39775791,
  author  = {Ghose, Upamanyu and Sproviero, William and Winchester, Laura and Amin, Najaf and Zhu, Taiyu and Newby, Danielle and Ulm, Brittany S and Papathanasiou, Angeliki and others},
  title   = {{Genome-wide association neural networks identify genes linked to family history of Alzheimer's disease}},
  journal = {Briefings in bioinformatics},
  year    = {2024},
  doi     = {10.1093/bib/bbae704},
  pmid    = {39775791},
  url     = {https://doi.org/10.1093/bib/bbae704}
}

@article{vanderlip2025-40491259,
  author  = {Vanderlip, C. R. and Stark, C. E. L.},
  title   = {{Integrating plasma p-tau217 and digital cognitive assessments for early detection in Alzheimer's disease}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2025},
  doi     = {10.1002/alz.70355},
  pmid    = {40491259},
  url     = {https://doi.org/10.1002/alz.70355}
}

@article{mehmood2020-32033462,
  author  = {Mehmood, A. and Maqsood, M. and Bashir, M. and Shuyuan, Y.},
  title   = {{A Deep Siamese Convolution Neural Network for Multi-Class Classification of Alzheimer Disease}},
  journal = {Brain sciences},
  year    = {2020},
  doi     = {10.3390/brainsci10020084},
  pmid    = {32033462},
  url     = {https://doi.org/10.3390/brainsci10020084}
}

@article{cuffaro2020-32556746,
  author  = {Cuffaro, L. and Di Lorenzo, F. and Bonavita, S. and Tedeschi, G. and Leocani, L. and Lavorgna, L.},
  title   = {{Dementia care and COVID-19 pandemic: a necessary digital revolution}},
  journal = {Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology},
  year    = {2020},
  doi     = {10.1007/s10072-020-04512-4},
  pmid    = {32556746},
  url     = {https://doi.org/10.1007/s10072-020-04512-4}
}

@article{stavropoulos2020-32429331,
  author  = {Stavropoulos, T. G. and Papastergiou, A. and Mpaltadoros, L. and Nikolopoulos, S. and Kompatsiaris, I.},
  title   = {{IoT Wearable Sensors and Devices in Elderly Care: A Literature Review}},
  journal = {Sensors (Basel, Switzerland)},
  year    = {2020},
  doi     = {10.3390/s20102826},
  pmid    = {32429331},
  url     = {https://doi.org/10.3390/s20102826}
}

@article{rossini2022-35388959,
  author  = {Rossini, P. M. and Miraglia, F. and Vecchio, F.},
  title   = {{Early dementia diagnosis, MCI-to-dementia risk prediction, and the role of machine learning methods for feature extraction from integrated biomarkers, in particular for EEG signal analysis}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2022},
  doi     = {10.1002/alz.12645},
  pmid    = {35388959},
  url     = {https://doi.org/10.1002/alz.12645}
}

@article{wang2022-35333038,
  author  = {Wang, Z. and Ye, J. and Zhang, K. and Ding, L. and Granzier-Nakajima, T. and Ranasinghe, J. C. and Xue, Y. and Sharma, S. and others},
  title   = {{Rapid Biomarker Screening of Alzheimer's Disease by Interpretable Machine Learning and Graphene-Assisted Raman Spectroscopy}},
  journal = {ACS nano},
  year    = {2022},
  doi     = {10.1021/acsnano.2c00538},
  pmid    = {35333038},
  url     = {https://doi.org/10.1021/acsnano.2c00538}
}

@article{aschwanden2020-32333585,
  author  = {Aschwanden, D. and Aichele, S. and Ghisletta, P. and Terracciano, A. and Kliegel, M. and Sutin, A. R. and Brown, J. and Allemand, M.},
  title   = {{Predicting Cognitive Impairment and Dementia: A Machine Learning Approach}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2020},
  doi     = {10.3233/jad-190967},
  pmid    = {32333585},
  url     = {https://doi.org/10.3233/jad-190967}
}

@article{stegmann2020-33442573,
  author  = {Stegmann, G. M. and Hahn, S. and Liss, J. and Shefner, J. and Rutkove, S. B. and Kawabata, K. and Bhandari, S. and Shelton, K. and others},
  title   = {{Repeatability of Commonly Used Speech and Language Features for Clinical Applications}},
  journal = {Digital biomarkers},
  year    = {2020},
  doi     = {10.1159/000511671},
  pmid    = {33442573},
  url     = {https://doi.org/10.1159/000511671}
}

@article{finucane2021-33536318,
  author  = {Finucane, A. M. and Bone, A. E. and Etkind, S. and Carr, D. and Meade, R. and Munoz-Arroyo, R. and Moine, S. and Iyayi-Igbinovia, A. and others},
  title   = {{How many people will need palliative care in Scotland by 2040? A mixed-method study of projected palliative care need and recommendations for service delivery}},
  journal = {BMJ open},
  year    = {2021},
  doi     = {10.1136/bmjopen-2020-041317},
  pmid    = {33536318},
  url     = {https://doi.org/10.1136/bmjopen-2020-041317}
}

@article{zhou2022-33971647,
  author  = {Zhou, H. and Park, C. and Shahbazi, M. and York, M. K. and Kunik, M. E. and Naik, A. D. and Najafi, B.},
  title   = {{Digital Biomarkers of Cognitive Frailty: The Value of Detailed Gait Assessment Beyond Gait Speed}},
  journal = {Gerontology},
  year    = {2022},
  doi     = {10.1159/000515939},
  pmid    = {33971647},
  url     = {https://doi.org/10.1159/000515939}
}

@article{lin2020-32967146,
  author  = {Lin, C. H. and Chiu, S. I. and Chen, T. F. and Jang, JR. and Chiu, M. J.},
  title   = {{Classifications of Neurodegenerative Disorders Using a Multiplex Blood Biomarkers-Based Machine Learning Model}},
  journal = {International journal of molecular sciences},
  year    = {2020},
  doi     = {10.3390/ijms21186914},
  pmid    = {32967146},
  url     = {https://doi.org/10.3390/ijms21186914}
}

@article{galvan2006-16641106,
  author  = {Galvan, V. and Gorostiza, O. F. and Banwait, S. and Ataie, M. and Logvinova, A. V. and Sitaraman, S. and Carlson, E. and Sagi, S. A. and others},
  title   = {{Reversal of Alzheimer's-like pathology and behavior in human APP transgenic mice by mutation of Asp664}},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year    = {2006},
  doi     = {10.1073/pnas.0509695103},
  pmid    = {16641106},
  url     = {https://doi.org/10.1073/pnas.0509695103}
}

@article{colciaghi2004-14872043,
  author  = {Colciaghi, F. and Marcello, E. and Borroni, B. and Zimmermann, M. and Caltagirone, C. and Cattabeni, F. and Padovani, A. and Di Luca, M.},
  title   = {{Platelet APP, ADAM 10 and BACE alterations in the early stages of Alzheimer disease}},
  journal = {Neurology},
  year    = {2004},
  doi     = {10.1212/01.wnl.0000106953.49802.9c},
  pmid    = {14872043},
  url     = {https://doi.org/10.1212/01.wnl.0000106953.49802.9c}
}

@article{roccati2025-41435153,
  author  = {Roccati, Eddy and Kitsos, Alex and Saunder, Timothy and Vickers, James Clement},
  title   = {{Using real world data to visualize longitudinal modifiable dementia risk factors in the community through an online interactive map}},
  journal = {Alzheimer s \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz70860_104566},
  pmid    = {41435153},
  url     = {https://doi.org/10.1002/alz70860_104566}
}

@article{rezaei2025-40675424,
  author  = {Rezaei, Sahar and Asadirad, Farzan and Motamed, Arash and Kamran, Mohammadsadegh and Parsa, Farzaneh and Samimi, Haniyeh and Ghannadikhosh, Parna and Zahmatyar, Mahdi and others},
  title   = {{Future of Alzheimer's detection: Advancing diagnostic accuracy through the integration of qEEG and artificial intelligence}},
  journal = {NeuroImage},
  year    = {2025},
  doi     = {10.1016/j.neuroimage.2025.121373},
  pmid    = {40675424},
  url     = {https://doi.org/10.1016/j.neuroimage.2025.121373}
}

@article{phalle2025-39917741,
  author  = {Phalle, Anuja and Gokhale, Devaki},
  title   = {{Navigating next-gen nutrition care using artificial intelligence-assisted dietary assessment tools—a scoping review of potential applications}},
  journal = {Frontiers in Nutrition},
  year    = {2025},
  doi     = {10.3389/fnut.2025.1518466},
  pmid    = {39917741},
  url     = {https://doi.org/10.3389/fnut.2025.1518466}
}

@article{richter2025-39994339,
  author  = {Richter, M. and Sobotnicka, Ewelina and Bednorz, Adam},
  title   = {{Cognitive performance classification of older patients using machine learning and electronic medical records}},
  journal = {Scientific Reports},
  year    = {2025},
  doi     = {10.1038/s41598-025-90460-y},
  pmid    = {39994339},
  url     = {https://doi.org/10.1038/s41598-025-90460-y}
}

@article{rawtaer2025-f66c6bec,
  author  = {Rawtaer, Iris and Jabbar, Khalid Bin Abdul and Subagdja, Budhitama and Saffari, Ehsan and Tan, Ah‐Hwee},
  title   = {{299. SENSORS IN-HOME FOR ELDER WELLBEING (SINEW): DIGITAL PHENOTYPING AND ARTIFICIAL INTELLIGENCE FOR EARLY DETECTION OF DEMENTIA}},
  journal = {The International Journal of Neuropsychopharmacology},
  year    = {2025},
  doi     = {10.1093/ijnp/pyaf052.136},
  url     = {https://doi.org/10.1093/ijnp/pyaf052.136}
}

@article{gramkow2026-41518717,
  author  = {Gramkow, Mathias Holsey and Gleerup, Helena Sophia and Simonsen, Anja Hviid and Waldemar, Gunhild and Frederiksen, Kristian Steen},
  title   = {{Digital biomarkers in early Alzheimer's disease from wearable or portable technology: A scoping review}},
  journal = {Journal of the Neurological Sciences},
  year    = {2026},
  doi     = {10.1016/j.jns.2026.125734},
  pmid    = {41518717},
  url     = {https://doi.org/10.1016/j.jns.2026.125734}
}

@article{zheng2025-a879517e,
  author  = {Zheng, Guojiang and Lü, Yang and Chen, Hui},
  title   = {{Deep Learning-Based Framework for Predicting Mild Cognitive Impairment Progression in Neurology Using Longitudinal MRI}},
  journal = {IEEE Access},
  year    = {2025},
  doi     = {10.1109/access.2025.3562432},
  url     = {https://doi.org/10.1109/access.2025.3562432}
}

@article{montesino2025-40144050,
  author  = {Montesino, Marion Ferrandez y and Guerchouche, Rachid and Lemaire, Justine and Brill, Esther and Klöppel, Stefan and Brémond, François and Solari, Fabio and Robert, Philippe H. and others},
  title   = {{Feasibility and acceptability of a remote computerized cognitive training employing telehealth in older adults with subjective cognitive complaints}},
  journal = {Digital Health},
  year    = {2025},
  doi     = {10.1177/20552076251324015},
  pmid    = {40144050},
  url     = {https://doi.org/10.1177/20552076251324015}
}

@article{walker2022-35164877,
  author  = {Walker, J. M. and Kazempour Dehkordi, S. and Fracassi, A. and Vanschoiack, A. and Pavenko, A. and Taglialatela, G. and Woltjer, R. and Richardson, T. E. and others},
  title   = {{Differential protein expression in the hippocampi of resilient individuals identified by digital spatial profiling}},
  journal = {Acta neuropathologica communications},
  year    = {2022},
  doi     = {10.1186/s40478-022-01324-9},
  pmid    = {35164877},
  url     = {https://doi.org/10.1186/s40478-022-01324-9}
}

@article{xiao2012-22539346,
  author  = {Xiao, Q. and Gil, S. C. and Yan, P. and Wang, Y. and Han, S. and Gonzales, E. and Perez, R. and Cirrito, JR. and others},
  title   = {{Role of phosphatidylinositol clathrin assembly lymphoid-myeloid leukemia (PICALM) in intracellular amyloid precursor protein (APP) processing and amyloid plaque pathogenesis}},
  journal = {The Journal of biological chemistry},
  year    = {2012},
  doi     = {10.1074/jbc.m111.338376},
  pmid    = {22539346},
  url     = {https://doi.org/10.1074/jbc.m111.338376}
}

@article{nuwer1997-9222209,
  author  = {Nuwer, M.},
  title   = {{Assessment of digital EEG, quantitative EEG, and EEG brain mapping: report of the American Academy of Neurology and the American Clinical Neurophysiology Society [RETIRED]}},
  journal = {Neurology},
  year    = {1997},
  doi     = {10.1212/wnl.49.1.277},
  pmid    = {9222209},
  url     = {https://doi.org/10.1212/wnl.49.1.277}
}

@article{hall2017-28494333,
  author  = {Hall, A. and Wilson, C. B. and Stanmore, E. and Todd, C.},
  title   = {{Implementing monitoring technologies in care homes for people with dementia: A qualitative exploration using Normalization Process Theory}},
  journal = {International journal of nursing studies},
  year    = {2017},
  doi     = {10.1016/j.ijnurstu.2017.04.008},
  pmid    = {28494333},
  url     = {https://doi.org/10.1016/j.ijnurstu.2017.04.008}
}

@article{boxer2020-31668596,
  author  = {Boxer, A. L. and Gold, M. and Feldman, H. and Boeve, B. F. and Dickinson, S. L. and Fillit, H. and Ho, C. and Paul, R. and others},
  title   = {{New directions in clinical trials for frontotemporal lobar degeneration: Methods and outcome measures}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2020},
  doi     = {10.1016/j.jalz.2019.06.4956},
  pmid    = {31668596},
  url     = {https://doi.org/10.1016/j.jalz.2019.06.4956}
}

@article{giannini2019-30851133,
  author  = {Giannini, L. A. A. and Xie, S. X. and McMillan, C. T. and Liang, M. and Williams, A. and Jester, C. and Rascovsky, K. and Wolk, D. A. and others},
  title   = {{Divergent patterns of TDP-43 and tau pathologies in primary progressive aphasia}},
  journal = {Annals of neurology},
  year    = {2019},
  doi     = {10.1002/ana.25465},
  pmid    = {30851133},
  url     = {https://doi.org/10.1002/ana.25465}
}

@article{akl2015-25585407,
  author  = {Akl, A. and Taati, B. and Mihailidis, A.},
  title   = {{Autonomous unobtrusive detection of mild cognitive impairment in older adults}},
  journal = {IEEE transactions on bio-medical engineering},
  year    = {2015},
  doi     = {10.1109/tbme.2015.2389149},
  pmid    = {25585407},
  url     = {https://doi.org/10.1109/tbme.2015.2389149}
}

@article{tiersen2021-34383672,
  author  = {Tiersen, F. and Batey, P. and Harrison, M. J. C. and Naar, L. and Serban, A. I. and Daniels, S. J. C. and Calvo, R. A.},
  title   = {{Smart Home Sensing and Monitoring in Households With Dementia: User-Centered Design Approach}},
  journal = {JMIR aging},
  year    = {2021},
  doi     = {10.2196/27047},
  pmid    = {34383672},
  url     = {https://doi.org/10.2196/27047}
}

@article{vecchio2020-32417784,
  author  = {Vecchio, F. and Miraglia, F. and Alù, F. and Menna, M. and Judica, E. and Cotelli, M. and Rossini, P. M.},
  title   = {{Classification of Alzheimer's Disease with Respect to Physiological Aging with Innovative EEG Biomarkers in a Machine Learning Implementation}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2020},
  doi     = {10.3233/jad-200171},
  pmid    = {32417784},
  url     = {https://doi.org/10.3233/jad-200171}
}

@article{talbot2022-35333111,
  author  = {Talbot, C. V. and Briggs, P.},
  title   = {{The use of digital technologies by people with mild-to-moderate dementia during the COVID-19 pandemic: A positive technology perspective}},
  journal = {Dementia (London, England)},
  year    = {2022},
  doi     = {10.1177/14713012221079477},
  pmid    = {35333111},
  url     = {https://doi.org/10.1177/14713012221079477}
}

@article{konig2019-31127764,
  author  = {König, A. and Linz, N. and Zeghari, R. and Klinge, X. and Tröger, J. and Alexandersson, J. and Robert, P.},
  title   = {{Detecting Apathy in Older Adults with Cognitive Disorders Using Automatic Speech Analysis}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2019},
  doi     = {10.3233/jad-181033},
  pmid    = {31127764},
  url     = {https://doi.org/10.3233/jad-181033}
}

@article{kim2023-36997138,
  author  = {Kim, M. J. and Youn, Y. C. and Paik, J.},
  title   = {{Deep learning-based EEG analysis to classify normal, mild cognitive impairment, and dementia: Algorithms and dataset}},
  journal = {NeuroImage},
  year    = {2023},
  doi     = {10.1016/j.neuroimage.2023.120054},
  pmid    = {36997138},
  url     = {https://doi.org/10.1016/j.neuroimage.2023.120054}
}

@article{blomeke2022-35655068,
  author  = {Blömeke, L. and Pils, M. and Kraemer-Schulien, V. and Dybala, A. and Schaffrath, A. and Kulawik, A. and Rehn, F. and Cousin, A. and others},
  title   = {{Quantitative detection of α-Synuclein and Tau oligomers and other aggregates by digital single particle counting}},
  journal = {NPJ Parkinson's disease},
  year    = {2022},
  doi     = {10.1038/s41531-022-00330-x},
  pmid    = {35655068},
  url     = {https://doi.org/10.1038/s41531-022-00330-x}
}

@article{trinchese2004-15174014,
  author  = {Trinchese, F. and Liu, S. and Battaglia, F. and Walter, S. and Mathews, P. M. and Arancio, O.},
  title   = {{Progressive age-related development of Alzheimer-like pathology in APP/PS1 mice}},
  journal = {Annals of neurology},
  year    = {2004},
  doi     = {10.1002/ana.20101},
  pmid    = {15174014},
  url     = {https://doi.org/10.1002/ana.20101}
}

@article{weyer2011-21522131,
  author  = {Weyer, S. W. and Klevanski, M. and Delekate, A. and Voikar, V. and Aydin, D. and Hick, M. and Filippov, M. and Drost, N. and others},
  title   = {{APP and APLP2 are essential at PNS and CNS synapses for transmission, spatial learning and LTP}},
  journal = {The EMBO journal},
  year    = {2011},
  doi     = {10.1038/emboj.2011.119},
  pmid    = {21522131},
  url     = {https://doi.org/10.1038/emboj.2011.119}
}

@article{alexopoulou2025-40415342,
  author  = {Alexopoulou, Zampeta-Sofia and Köhler, Stefanie and Mallick, Elisa and Tröger, Johannes and Linz, Nicklas and Spruth, Eike Jakob and Fließbach, Klaus and Bartels, Claudia and others},
  title   = {{Speech-based digital cognitive assessments for detection of mild cognitive impairment: Validation against paper-based neurocognitive assessment scores}},
  journal = {Journal of Alzheimer s Disease},
  year    = {2025},
  doi     = {10.1177/13872877251343296},
  pmid    = {40415342},
  url     = {https://doi.org/10.1177/13872877251343296}
}

@article{asaduzzaman2025-4f4d3a10,
  author  = {Asaduzzaman, Md and Alom, Md. Khorshed and Karim, Md. Ebtidaul},
  title   = {{ALZENET: Deep learning-based early prediction of Alzheimer's disease through magnetic resonance imaging analysis}},
  journal = {Telematics and Informatics Reports},
  year    = {2025},
  doi     = {10.1016/j.teler.2025.100189},
  url     = {https://doi.org/10.1016/j.teler.2025.100189}
}

@article{ports2025-40034839,
  author  = {Ports, Kayleen Deanna and Dai, Jiahui and Conniff, Kyle R and Corrada, María M. and Manson, Spero M. and O’Connell, Joan M. and Jiang, Luohua},
  title   = {{Machine learning to predict dementia for American Indian and Alaska native peoples: a retrospective cohort study}},
  journal = {The Lancet Regional Health - Americas},
  year    = {2025},
  doi     = {10.1016/j.lana.2025.101013},
  pmid    = {40034839},
  url     = {https://doi.org/10.1016/j.lana.2025.101013}
}

@article{mungas2025-40747592,
  author  = {Mungas, Dan and Gavett, Brandon E. and Rojas‐Saunero, Liliana Paloma and Zhou, Yixuan and Hayes‐Larson, Eleanor and Shaw, Crystal L. and Farias, Sarah Tomaszewski and Widaman, Keith F. and others},
  title   = {{Machine learning diagnosis of cognitive impairment and dementia in harmonized older adult cohorts}},
  journal = {Alzheimer s \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz.70508},
  pmid    = {40747592},
  url     = {https://doi.org/10.1002/alz.70508}
}

@article{vinay2025-40323948,
  author  = {Vinay, Rasita and Probst, Jonas and Huynh, Panitda and Schlögl, Mathias and Kowatsch, Tobias and Nißen, Marcia},
  title   = {{Top-funded digital health companies offering lifestyle interventions for dementia prevention: Company overview and evidence analysis}},
  journal = {PLoS ONE},
  year    = {2025},
  doi     = {10.1371/journal.pone.0323390},
  pmid    = {40323948},
  url     = {https://doi.org/10.1371/journal.pone.0323390}
}

@article{lennon2026-41554956,
  author  = {Lennon, Matthew J. and Sachdev, Perminder Singh},
  title   = {{Vascular cognitive impairment and dementia: Prevention, treatments, mechanisms and management options for the future}},
  journal = {Neuropsychopharmacology},
  year    = {2026},
  doi     = {10.1038/s41386-026-02331-3},
  pmid    = {41554956},
  url     = {https://doi.org/10.1038/s41386-026-02331-3}
}

@article{wang2025-40141072,
  author  = {Wang, Kesheng and Adjeroh, Donald and Fang, Wei and Walter, Suzy Mascaro and Xiao, Danqing and Piamjariyakul, Ubolrat and Di Xu, Chun},
  title   = {{Comparison of Deep Learning and Traditional Machine Learning Models for Predicting Mild Cognitive Impairment Using Plasma Proteomic Biomarkers}},
  journal = {International Journal of Molecular Sciences},
  year    = {2025},
  doi     = {10.3390/ijms26062428},
  pmid    = {40141072},
  url     = {https://doi.org/10.3390/ijms26062428}
}

@article{wu2025-40260707,
  author  = {Wu, Yilei and Dong, Zijian and Li, Hongwei and Chong, Yao Feng Victor and Ji, Fang and Chong, Joanna Su Xian and Tang, Nathanael Ren Jie and Hilal, Saima and others},
  title   = {{WMH ‐ DualTasker : A Weakly Supervised Deep Learning Model for Automated White Matter Hyperintensities Segmentation and Visual Rating Prediction}},
  journal = {Human Brain Mapping},
  year    = {2025},
  doi     = {10.1002/hbm.70212},
  pmid    = {40260707},
  url     = {https://doi.org/10.1002/hbm.70212}
}

@article{zajaclamparska2019-31775849,
  author  = {Zając-Lamparska, L. and Wiłkość-Dębczyńska, M. and Wojciechowski, A. and Podhorecka, M. and Polak-Szabela, A. and Ł, Warchoł and Kędziora-Kornatowska, K. and Araszkiewicz, A. and others},
  title   = {{Effects of virtual reality-based cognitive training in older adults living without and with mild dementia: a pretest-posttest design pilot study}},
  journal = {BMC research notes},
  year    = {2019},
  doi     = {10.1186/s13104-019-4810-2},
  pmid    = {31775849},
  url     = {https://doi.org/10.1186/s13104-019-4810-2}
}

@article{wilks2021-35037593,
  author  = {Wilks, H. and Aschenbrenner, A. J. and Gordon, B. A. and Balota, D. A. and Fagan, A. M. and Musiek, E. and Balls-Berry, J. and Benzinger, T. L. S. and others},
  title   = {{Sharper in the morning: Cognitive time of day effects revealed with high-frequency smartphone testing}},
  journal = {Journal of clinical and experimental neuropsychology},
  year    = {2021},
  doi     = {10.1080/13803395.2021.2009447},
  pmid    = {35037593},
  url     = {https://doi.org/10.1080/13803395.2021.2009447}
}

@article{vanderlip2024-39239892,
  author  = {Vanderlip, C. R. and Stark, C. E. L. and {Alzheimer's Disease Neuroimaging Initiative}},
  title   = {{Digital cognitive assessments as low-burden markers for predicting future cognitive decline and tau accumulation across the Alzheimer's spectrum}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2024},
  doi     = {10.1002/alz.14154},
  pmid    = {39239892},
  url     = {https://doi.org/10.1002/alz.14154}
}

@article{haque2021-32340935,
  author  = {Haque, R. U. and Pongos, A. L. and Manzanares, C. M. and Lah, J. J. and Levey, A. I. and Clifford, G. D.},
  title   = {{Deep Convolutional Neural Networks and Transfer Learning for Measuring Cognitive Impairment Using Eye-Tracking in a Distributed Tablet-Based Environment}},
  journal = {IEEE transactions on bio-medical engineering},
  year    = {2021},
  doi     = {10.1109/tbme.2020.2990734},
  pmid    = {32340935},
  url     = {https://doi.org/10.1109/tbme.2020.2990734}
}

@article{ding2019-30398430,
  author  = {Ding, Y. and Sohn, J. H. and Kawczynski, M. G. and Trivedi, H. and Harnish, R. and Jenkins, N. W. and Lituiev, D. and Copeland, T. P. and others},
  title   = {{A Deep Learning Model to Predict a Diagnosis of Alzheimer Disease by Using 18 F-FDG PET of the Brain}},
  journal = {Radiology},
  year    = {2019},
  doi     = {10.1148/radiol.2018180958},
  pmid    = {30398430},
  url     = {https://doi.org/10.1148/radiol.2018180958}
}

@article{basaia2019-30584016,
  author  = {Basaia, S. and Agosta, F. and Wagner, L. and Canu, E. and Magnani, G. and Santangelo, R. and Filippi, M. and {Alzheimer's Disease Neuroimaging Initiative}},
  title   = {{Automated classification of Alzheimer's disease and mild cognitive impairment using a single MRI and deep neural networks}},
  journal = {NeuroImage. Clinical},
  year    = {2019},
  doi     = {10.1016/j.nicl.2018.101645},
  pmid    = {30584016},
  url     = {https://doi.org/10.1016/j.nicl.2018.101645}
}

@article{li2021-34971042,
  author  = {Li, Clara and Zeng, Xiaoyi and Wang, Kun and Neugroschl, Judith A and Aloysi, Amy and Cai, Dongming and Martin, Jane and Sewell, Margaret and others},
  title   = {{Smartphone ownership and usage in Chinese- and English-speaking older adults}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2021},
  doi     = {10.1002/alz.054680},
  pmid    = {34971042},
  url     = {https://doi.org/10.1002/alz.054680}
}

@article{millett2018-29140858,
  author  = {Millett, Geneva and Naglie, Gary and Upshur, Ross and Jaakkimainen, Liisa and Charles, Jocelyn and Tierney, Mary C},
  title   = {{Computerized Cognitive Testing in Primary Care: A Qualitative Study}},
  journal = {Alzheimer disease and associated disorders},
  year    = {2018},
  doi     = {10.1097/wad.0000000000000219},
  pmid    = {29140858},
  url     = {https://doi.org/10.1097/wad.0000000000000219}
}

@article{minen2021-32669020,
  author  = {Minen, Mia T and Gopal, Ariana and Sahyoun, Gabriella and Stieglitz, Eric and Torous, John},
  title   = {{The Functionality, Evidence, and Privacy Issues Around Smartphone Apps for the Top Neuropsychiatric Conditions}},
  journal = {The Journal of neuropsychiatry and clinical neurosciences},
  year    = {2021},
  doi     = {10.1176/appi.neuropsych.19120353},
  pmid    = {32669020},
  url     = {https://doi.org/10.1176/appi.neuropsych.19120353}
}

@article{margarido2022-35314766,
  author  = {Margarido, Milena Guessi and Shah, Amika and Seto, Emily},
  title   = {{Smartphone applications for informal caregivers of chronically ill patients: a scoping review}},
  journal = {NPJ digital medicine},
  year    = {2022},
  doi     = {10.1038/s41746-022-00567-z},
  pmid    = {35314766},
  url     = {https://doi.org/10.1038/s41746-022-00567-z}
}

@article{chutia2025-39982201,
  author  = {Chutia, Porimita and Tripathi, Shailendra Mohan and Jv, Ashwin},
  title   = {{The digitalization of psychopathology: 'TV sign' and 'Smartphone sign' as red flags for dementia}},
  journal = {Neurocase},
  year    = {2025},
  doi     = {10.1080/13554794.2025.2467925},
  pmid    = {39982201},
  url     = {https://doi.org/10.1080/13554794.2025.2467925}
}

@article{biechele2021-33385560,
  author  = {Biechele, G. and Wind, K. and Blume, T. and Sacher, C. and Beyer, L. and Eckenweber, F. and Franzmeier, N. and Ewers, M. and others},
  title   = {{Microglial activation in the right amygdala-entorhinal-hippocampal complex is associated with preserved spatial learning in AppNL-G-F mice}},
  journal = {NeuroImage},
  year    = {2021},
  doi     = {10.1016/j.neuroimage.2020.117707},
  pmid    = {33385560},
  url     = {https://doi.org/10.1016/j.neuroimage.2020.117707}
}

@article{maroco2011-21849043,
  author  = {Maroco, J. and Silva, D. and Rodrigues, A. and Guerreiro, M. and Santana, I. and de Mendonça, A.},
  title   = {{Data mining methods in the prediction of Dementia: A real-data comparison of the accuracy, sensitivity and specificity of linear discriminant analysis, logistic regression, neural networks, support vector machines, classification trees and random forests}},
  journal = {BMC research notes},
  year    = {2011},
  doi     = {10.1186/1756-0500-4-299},
  pmid    = {21849043},
  url     = {https://doi.org/10.1186/1756-0500-4-299}
}

@article{ieracitano2020-31884180,
  author  = {Ieracitano, C. and Mammone, N. and Hussain, A. and Morabito, F. C.},
  title   = {{A novel multi-modal machine learning based approach for automatic classification of EEG recordings in dementia}},
  journal = {Neural networks : the official journal of the International Neural Network Society},
  year    = {2020},
  doi     = {10.1016/j.neunet.2019.12.006},
  pmid    = {31884180},
  url     = {https://doi.org/10.1016/j.neunet.2019.12.006}
}

@article{wangmo2019-31856798,
  author  = {Wangmo, T. and Lipps, M. and Kressig, R. W. and Ienca, M.},
  title   = {{Ethical concerns with the use of intelligent assistive technology: findings from a qualitative study with professional stakeholders}},
  journal = {BMC medical ethics},
  year    = {2019},
  doi     = {10.1186/s12910-019-0437-z},
  pmid    = {31856798},
  url     = {https://doi.org/10.1186/s12910-019-0437-z}
}

@article{popuri2020-32614505,
  author  = {Popuri, K. and Ma, D. and Wang, L. and Beg, M. F.},
  title   = {{Using machine learning to quantify structural MRI neurodegeneration patterns of Alzheimer's disease into dementia score: Independent validation on 8,834 images from ADNI, AIBL, OASIS, and MIRIAD databases}},
  journal = {Human brain mapping},
  year    = {2020},
  doi     = {10.1002/hbm.25115},
  pmid    = {32614505},
  url     = {https://doi.org/10.1002/hbm.25115}
}

@article{mathotaarachchi2017-28756942,
  author  = {Mathotaarachchi, S. and Pascoal, T. A. and Shin, M. and Benedet, A. L. and Kang, M. S. and Beaudry, T. and Fonov, V. S. and Gauthier, S. and others},
  title   = {{Identifying incipient dementia individuals using machine learning and amyloid imaging}},
  journal = {Neurobiology of aging},
  year    = {2017},
  doi     = {10.1016/j.neurobiolaging.2017.06.027},
  pmid    = {28756942},
  url     = {https://doi.org/10.1016/j.neurobiolaging.2017.06.027}
}

@article{li2022-35183766,
  author  = {Li, R. and Wang, X. and Lawler, K. and Garg, S. and Bai, Q. and Alty, J.},
  title   = {{Applications of artificial intelligence to aid early detection of dementia: A scoping review on current capabilities and future directions}},
  journal = {Journal of biomedical informatics},
  year    = {2022},
  doi     = {10.1016/j.jbi.2022.104030},
  pmid    = {35183766},
  url     = {https://doi.org/10.1016/j.jbi.2022.104030}
}

@article{uysal2020-32126274,
  author  = {Uysal, G. and Ozturk, M.},
  title   = {{Hippocampal atrophy based Alzheimer's disease diagnosis via machine learning methods}},
  journal = {Journal of neuroscience methods},
  year    = {2020},
  doi     = {10.1016/j.jneumeth.2020.108669},
  pmid    = {32126274},
  url     = {https://doi.org/10.1016/j.jneumeth.2020.108669}
}

@article{enshaeifar2018-29723236,
  author  = {Enshaeifar, S. and Zoha, A. and Markides, A. and Skillman, S. and Acton, S. T. and Elsaleh, T. and Hassanpour, M. and Ahrabian, A. and others},
  title   = {{Health management and pattern analysis of daily living activities of people with dementia using in-home sensors and machine learning techniques}},
  journal = {PloS one},
  year    = {2018},
  doi     = {10.1371/journal.pone.0195605},
  pmid    = {29723236},
  url     = {https://doi.org/10.1371/journal.pone.0195605}
}

@article{lazarou2016-27636843,
  author  = {Lazarou, I. and Karakostas, A. and Stavropoulos, T. G. and Tsompanidis, T. and Meditskos, G. and Kompatsiaris, I. and Tsolaki, M.},
  title   = {{A Novel and Intelligent Home Monitoring System for Care Support of Elders with Cognitive Impairment}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2016},
  doi     = {10.3233/jad-160348},
  pmid    = {27636843},
  url     = {https://doi.org/10.3233/jad-160348}
}

@article{bucholc2019-31402810,
  author  = {Bucholc, M. and Ding, X. and Wang, H. and Glass, D. H. and Prasad, G. and Maguire, L. P. and Bjourson, A. J. and others},
  title   = {{A practical computerized decision support system for predicting the severity of Alzheimer's disease of an individual}},
  journal = {Expert systems with applications},
  year    = {2019},
  doi     = {10.1016/j.eswa.2019.04.022},
  pmid    = {31402810},
  url     = {https://doi.org/10.1016/j.eswa.2019.04.022}
}

@article{bron2021-34118592,
  author  = {Bron, E. E. and Klein, S. and Papma, J. M. and Jiskoot, L. C. and Venkatraghavan, V. and Linders, J. and Aalten, P. and De Deyn, P. P. and others},
  title   = {{Cross-cohort generalizability of deep and conventional machine learning for MRI-based diagnosis and prediction of Alzheimer's disease}},
  journal = {NeuroImage. Clinical},
  year    = {2021},
  doi     = {10.1016/j.nicl.2021.102712},
  pmid    = {34118592},
  url     = {https://doi.org/10.1016/j.nicl.2021.102712}
}

@article{saleem2022-35629237,
  author  = {Saleem, T. J. and Zahra, SR. and Wu, F. and Alwakeel, A. and Alwakeel, M. and Jeribi, F. and Hijji, M.},
  title   = {{Deep Learning-Based Diagnosis of Alzheimer's Disease}},
  journal = {Journal of personalized medicine},
  year    = {2022},
  doi     = {10.3390/jpm12050815},
  pmid    = {35629237},
  url     = {https://doi.org/10.3390/jpm12050815}
}

@article{banbury2019-31631761,
  author  = {Banbury, A. and Parkinson, L. and Gordon, S. and Wood, D.},
  title   = {{Implementing a peer-support programme by group videoconferencing for isolated carers of people with dementia}},
  journal = {Journal of telemedicine and telecare},
  year    = {2019},
  doi     = {10.1177/1357633x19873793},
  pmid    = {31631761},
  url     = {https://doi.org/10.1177/1357633x19873793}
}

@article{qiu2024-38335558,
  author  = {Qiu, Y. and Cheng, F.},
  title   = {{Artificial intelligence for drug discovery and development in Alzheimer's disease}},
  journal = {Current opinion in structural biology},
  year    = {2024},
  doi     = {10.1016/j.sbi.2024.102776},
  pmid    = {38335558},
  url     = {https://doi.org/10.1016/j.sbi.2024.102776}
}

@article{meng2024-39358810,
  author  = {Meng, L. and Jin, H. and Yulug, B. and Altay, O. and Li, X. and Hanoglu, L. and Cankaya, S. and Coskun, E. and others},
  title   = {{Multi-omics analysis reveals the key factors involved in the severity of the Alzheimer's disease}},
  journal = {Alzheimer's research \& therapy},
  year    = {2024},
  doi     = {10.1186/s13195-024-01578-6},
  pmid    = {39358810},
  url     = {https://doi.org/10.1186/s13195-024-01578-6}
}

@article{chang2021-33586518,
  author  = {Chang, C. H. and Lin, C. H. and Liu, C. Y. and Huang, C. S. and Chen, S. J. and Lin, W. C. and Yang, H. T. and Lane, H. Y.},
  title   = {{Plasma d-glutamate levels for detecting mild cognitive impairment and Alzheimer's disease: Machine learning approaches}},
  journal = {Journal of psychopharmacology (Oxford, England)},
  year    = {2021},
  doi     = {10.1177/0269881120972331},
  pmid    = {33586518},
  url     = {https://doi.org/10.1177/0269881120972331}
}

@article{sabo2001-11425871,
  author  = {Sabo, S. L. and Ikin, A. F. and Buxbaum, J. D. and Greengard, P.},
  title   = {{The Alzheimer amyloid precursor protein (APP) and FE65, an APP-binding protein, regulate cell movement}},
  journal = {The Journal of cell biology},
  year    = {2001},
  doi     = {10.1083/jcb.153.7.1403},
  pmid    = {11425871},
  url     = {https://doi.org/10.1083/jcb.153.7.1403}
}

@article{butterfield2010-19854267,
  author  = {Butterfield, D. A. and Galvan, V. and Lange, M. B. and Tang, H. and Sowell, R. A. and Spilman, P. and Fombonne, J. and Gorostiza, O. and others},
  title   = {{In vivo oxidative stress in brain of Alzheimer disease transgenic mice: Requirement for methionine 35 in amyloid beta-peptide of APP}},
  journal = {Free radical biology \& medicine},
  year    = {2010},
  doi     = {10.1016/j.freeradbiomed.2009.10.035},
  pmid    = {19854267},
  url     = {https://doi.org/10.1016/j.freeradbiomed.2009.10.035}
}

@article{wilcock2004-15588287,
  author  = {Wilcock, D. M. and Rojiani, A. and Rosenthal, A. and Subbarao, S. and Freeman, M. J. and Gordon, M. N. and Morgan, D.},
  title   = {{Passive immunotherapy against Abeta in aged APP-transgenic mice reverses cognitive deficits and depletes parenchymal amyloid deposits in spite of increased vascular amyloid and microhemorrhage}},
  journal = {Journal of neuroinflammation},
  year    = {2004},
  doi     = {10.1186/1742-2094-1-24},
  pmid    = {15588287},
  url     = {https://doi.org/10.1186/1742-2094-1-24}
}

@article{bauerl2018-29575030,
  author  = {Bäuerl, C. and Collado, M. C. and Diaz Cuevas, A. and Viña, J. and Pérez Martínez, G.},
  title   = {{Shifts in gut microbiota composition in an APP/PSS1 transgenic mouse model of Alzheimer's disease during lifespan}},
  journal = {Letters in applied microbiology},
  year    = {2018},
  doi     = {10.1111/lam.12882},
  pmid    = {29575030},
  url     = {https://doi.org/10.1111/lam.12882}
}

@article{alasiry2025-40596195,
  author  = {Alasiry, Areej and Shinan, Khlood and Alsadhan, Abeer Abdullah and Alhazmi, Hanan E. and Alanazi, Fatmah and Ashraf, Muhammad Usman and Muhammad, Taseer},
  title   = {{A novel neuroimaging based early detection framework for alzheimer disease using deep learning}},
  journal = {Scientific Reports},
  year    = {2025},
  doi     = {10.1038/s41598-025-05529-5},
  pmid    = {40596195},
  url     = {https://doi.org/10.1038/s41598-025-05529-5}
}

@article{khan2025-40735445,
  author  = {Khan, Waqar Ali and Khan, Muhammad Shahbaz and Qasem, Sultan Noman and Ghaban, Wad and Saeed, Faisal and Hanif, Muhammad Fainan and Ahmad, Jawad Elsayed},
  title   = {{An explainable and efficient deep learning framework for EEG-based diagnosis of Alzheimer's disease and frontotemporal dementia}},
  journal = {Frontiers in Medicine},
  year    = {2025},
  doi     = {10.3389/fmed.2025.1590201},
  pmid    = {40735445},
  url     = {https://doi.org/10.3389/fmed.2025.1590201}
}

@article{tagliente2025-39850970,
  author  = {Tagliente, Serena and Minafra, Brigida and Aresta, Simona and Santacesaria, Paola and Buccoliero, Andrea and Palmirotta, Cinzia and Lagravinese, Gianvito and Mongelli, Davide and others},
  title   = {{Effectiveness of a home-based computerized cognitive training in Parkinson's disease: a pilot randomized cross-over study}},
  journal = {Frontiers in Psychology},
  year    = {2025},
  doi     = {10.3389/fpsyg.2024.1531688},
  pmid    = {39850970},
  url     = {https://doi.org/10.3389/fpsyg.2024.1531688}
}

@article{ye2025-39985041,
  author  = {Ye, Yi and Chen, Qing and Li, Ruixuan and Wang, Xiaoyi and Sun, Yueling and Li, Fangjiang and Liu, Xiaoping and Wang, Le and others},
  title   = {{The efficacy of computerized cognitive training in patients with coronary heart disease and cognitive impairment, no dementia: study protocol for a randomized controlled trial}},
  journal = {Trials},
  year    = {2025},
  doi     = {10.1186/s13063-025-08745-6},
  pmid    = {39985041},
  url     = {https://doi.org/10.1186/s13063-025-08745-6}
}

@article{berridge2025-40313054,
  author  = {Berridge, Clara W. and Turner, Natalie R. and Lober, William B. and Demiris, George and JEFFREY A., K. A. Y. E.},
  title   = {{Sharing patient technology preferences with care networks: Stakeholders’ views of the “Let’s Talk Tech” decision aid for dementia care}},
  journal = {Journal of Alzheimer s Disease},
  year    = {2025},
  doi     = {10.1177/13872877251332659},
  pmid    = {40313054},
  url     = {https://doi.org/10.1177/13872877251332659}
}

@article{arlati2021-33646164,
  author  = {Arlati, S. and Di Santo, S. G. and Franchini, F. and Mondellini, M. and Filiputti, B. and Luchi, M. and Ratto, F. and Ferrigno, G. and others},
  title   = {{Acceptance and Usability of Immersive Virtual Reality in Older Adults with Objective and Subjective Cognitive Decline}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2021},
  doi     = {10.3233/jad-201431},
  pmid    = {33646164},
  url     = {https://doi.org/10.3233/jad-201431}
}

@article{dwolatzky2003-14594456,
  author  = {Dwolatzky, T. and Whitehead, V. and Doniger, G. M. and Simon, E. S. and Schweiger, A. and Jaffe, D. and Chertkow, H.},
  title   = {{Validity of a novel computerized cognitive battery for mild cognitive impairment}},
  journal = {BMC geriatrics},
  year    = {2003},
  doi     = {10.1186/1471-2318-3-4},
  pmid    = {14594456},
  url     = {https://doi.org/10.1186/1471-2318-3-4}
}

@article{ohman2021-34295959,
  author  = {Öhman, F. and Hassenstab, J. and Berron, D. and Schöll, M. and Papp, K. V.},
  title   = {{Current advances in digital cognitive assessment for preclinical Alzheimer's disease}},
  journal = {Alzheimer's \& dementia (Amsterdam, Netherlands)},
  year    = {2021},
  doi     = {10.1002/dad2.12217},
  pmid    = {34295959},
  url     = {https://doi.org/10.1002/dad2.12217}
}

@article{cysique2006-16343841,
  author  = {Cysique, L. A. and Maruff, P. and Darby, D. and Brew, B. J.},
  title   = {{The assessment of cognitive function in advanced HIV-1 infection and AIDS dementia complex using a new computerised cognitive test battery}},
  journal = {Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists},
  year    = {2006},
  doi     = {10.1016/j.acn.2005.07.011},
  pmid    = {16343841},
  url     = {https://doi.org/10.1016/j.acn.2005.07.011}
}

@article{limone2021-34573148,
  author  = {Limone, P. and Toto, G. A.},
  title   = {{Psychological and Emotional Effects of Digital Technology on Children in COVID-19 Pandemic}},
  journal = {Brain sciences},
  year    = {2021},
  doi     = {10.3390/brainsci11091126},
  pmid    = {34573148},
  url     = {https://doi.org/10.3390/brainsci11091126}
}

@article{scanlon2016-26113397,
  author  = {Scanlon, L. and O'Shea, E. and O'Caoimh, R. and Timmons, S.},
  title   = {{Usability and Validity of a Battery of Computerised Cognitive Screening Tests for Detecting Cognitive Impairment}},
  journal = {Gerontology},
  year    = {2016},
  doi     = {10.1159/000433432},
  pmid    = {26113397},
  url     = {https://doi.org/10.1159/000433432}
}

@article{wang2021-33767197,
  author  = {Wang, J. and Ma, A. and Chang, Y. and Gong, J. and Jiang, Y. and Qi, R. and Wang, C. and Fu, H. and others},
  title   = {{scGNN is a novel graph neural network framework for single-cell RNA-Seq analyses}},
  journal = {Nature communications},
  year    = {2021},
  doi     = {10.1038/s41467-021-22197-x},
  pmid    = {33767197},
  url     = {https://doi.org/10.1038/s41467-021-22197-x}
}

@article{rodriguez2021-33589615,
  author  = {Rodriguez, S. and Hug, C. and Todorov, P. and Moret, N. and Boswell, S. A. and Evans, K. and Zhou, G. and Johnson, N. T. and others},
  title   = {{Machine learning identifies candidates for drug repurposing in Alzheimer's disease}},
  journal = {Nature communications},
  year    = {2021},
  doi     = {10.1038/s41467-021-21330-0},
  pmid    = {33589615},
  url     = {https://doi.org/10.1038/s41467-021-21330-0}
}

@article{gualtieri2006-17014981,
  author  = {Gualtieri, C. T. and Johnson, L. G.},
  title   = {{Reliability and validity of a computerized neurocognitive test battery, CNS Vital Signs}},
  journal = {Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists},
  year    = {2006},
  doi     = {10.1016/j.acn.2006.05.007},
  pmid    = {17014981},
  url     = {https://doi.org/10.1016/j.acn.2006.05.007}
}

@article{dehaan2009-19698093,
  author  = {de Haan, W. and Pijnenburg, Y. A. and Strijers, R. L. and van der Made, Y. and van der Flier, W. M. and Scheltens, P. and Stam, C. J.},
  title   = {{Functional neural network analysis in frontotemporal dementia and Alzheimer's disease using EEG and graph theory}},
  journal = {BMC neuroscience},
  year    = {2009},
  doi     = {10.1186/1471-2202-10-101},
  pmid    = {19698093},
  url     = {https://doi.org/10.1186/1471-2202-10-101}
}

@article{qiu2022-35725739,
  author  = {Qiu, S. and Miller, M. I. and Joshi, P. S. and Lee, J. C. and Xue, C. and Ni, Y. and Wang, Y. and De Anda-Duran, I. and others},
  title   = {{Multimodal deep learning for Alzheimer's disease dementia assessment}},
  journal = {Nature communications},
  year    = {2022},
  doi     = {10.1038/s41467-022-31037-5},
  pmid    = {35725739},
  url     = {https://doi.org/10.1038/s41467-022-31037-5}
}

@article{roshanzamir2021-33750385,
  author  = {Roshanzamir, A. and Aghajan, H. and Soleymani Baghshah, M.},
  title   = {{Transformer-based deep neural network language models for Alzheimer's disease risk assessment from targeted speech}},
  journal = {BMC medical informatics and decision making},
  year    = {2021},
  doi     = {10.1186/s12911-021-01456-3},
  pmid    = {33750385},
  url     = {https://doi.org/10.1186/s12911-021-01456-3}
}

@article{eisdorfer2003-12937331,
  author  = {Eisdorfer, Carl and Czaja, Sara J. and Loewenstein, David and Rubert, Mark P. and Argüelles, Soledad and Mitrani, Victoria Behar and Szapocznik, José},
  title   = {{The Effect of a Family Therapy and Technology-Based Intervention on Caregiver Depression}},
  journal = {The Gerontologist},
  year    = {2003},
  doi     = {10.1093/geront/43.4.521},
  pmid    = {12937331},
  url     = {https://doi.org/10.1093/geront/43.4.521}
}

@article{wahlberg2012-22655593,
  author  = {Wahlberg, L. U. and Lind, G. and Almqvist, P. M. and Kusk, P. and Tornøe, J. and Juliusson, B. and Söderman, M. and Selldén, E. and others},
  title   = {{Targeted delivery of nerve growth factor via encapsulated cell biodelivery in Alzheimer disease: a technology platform for restorative neurosurgery}},
  journal = {Journal of neurosurgery},
  year    = {2012},
  doi     = {10.3171/2012.2.jns11714},
  pmid    = {22655593},
  url     = {https://doi.org/10.3171/2012.2.jns11714}
}

@article{agbavor2022-36812634,
  author  = {Agbavor, F. and Liang, H.},
  title   = {{Predicting dementia from spontaneous speech using large language models}},
  journal = {PLOS digital health},
  year    = {2022},
  doi     = {10.1371/journal.pdig.0000168},
  pmid    = {36812634},
  url     = {https://doi.org/10.1371/journal.pdig.0000168}
}

@article{li2007-17698538,
  author  = {Li, S. and Shi, F. and Pu, F. and Li, X. and Jiang, T. and Xie, S. and Wang, Y.},
  title   = {{Hippocampal shape analysis of Alzheimer disease based on machine learning methods}},
  journal = {AJNR. American journal of neuroradiology},
  year    = {2007},
  doi     = {10.3174/ajnr.a0620},
  pmid    = {17698538},
  url     = {https://doi.org/10.3174/ajnr.a0620}
}

@article{sabbagh2020-32463070,
  author  = {Sabbagh, M. N. and Boada, M. and Borson, S. and Doraiswamy, P. M. and Dubois, B. and Ingram, J. and Iwata, A. and Porsteinsson, A. P. and others},
  title   = {{Early Detection of Mild Cognitive Impairment (MCI) in an At-Home Setting}},
  journal = {The journal of prevention of Alzheimer's disease},
  year    = {2020},
  doi     = {10.14283/jpad.2020.22},
  pmid    = {32463070},
  url     = {https://doi.org/10.14283/jpad.2020.22}
}

@article{oscar2017-28329835,
  author  = {Oscar, N. and Fox, P. A. and Croucher, R. and Wernick, R. and Keune, J. and Hooker, K.},
  title   = {{Machine Learning, Sentiment Analysis, and Tweets: An Examination of Alzheimer's Disease Stigma on Twitter}},
  journal = {The journals of gerontology. Series B, Psychological sciences and social sciences},
  year    = {2017},
  doi     = {10.1093/geronb/gbx014},
  pmid    = {28329835},
  url     = {https://doi.org/10.1093/geronb/gbx014}
}

@article{meiland2012-22360649,
  author  = {Meiland, F. J. and Bouman, A. I. and Sävenstedt, S. and Bentvelzen, S. and Davies, R. J. and Mulvenna, M. D. and Nugent, C. D. and Moelaert, F. and others},
  title   = {{Usability of a new electronic assistive device for community-dwelling persons with mild dementia}},
  journal = {Aging \& mental health},
  year    = {2012},
  doi     = {10.1080/13607863.2011.651433},
  pmid    = {22360649},
  url     = {https://doi.org/10.1080/13607863.2011.651433}
}

@article{bradwell2019-31558461,
  author  = {Bradwell, H. L. and Edwards, K. J. and Winnington, R. and Thill, S. and Jones, R. B.},
  title   = {{Companion robots for older people: importance of user-centred design demonstrated through observations and focus groups comparing preferences of older people and roboticists in South West England}},
  journal = {BMJ open},
  year    = {2019},
  doi     = {10.1136/bmjopen-2019-032468},
  pmid    = {31558461},
  url     = {https://doi.org/10.1136/bmjopen-2019-032468}
}

@article{nori2019-31276468,
  author  = {Nori, V. S. and Hane, C. A. and Martin, D. C. and Kravetz, A. D. and Sanghavi, D. M.},
  title   = {{Identifying incident dementia by applying machine learning to a very large administrative claims dataset}},
  journal = {PloS one},
  year    = {2019},
  doi     = {10.1371/journal.pone.0203246},
  pmid    = {31276468},
  url     = {https://doi.org/10.1371/journal.pone.0203246}
}

@article{shin2021-34032515,
  author  = {Shin, N. Y. and Bang, M. and Yoo, S. W. and Kim, J. S. and Yun, E. and Yoon, U. and Han, K. and Ahn, K. J. and others},
  title   = {{Cortical Thickness from MRI to Predict Conversion from Mild Cognitive Impairment to Dementia in Parkinson Disease: A Machine Learning-based Model}},
  journal = {Radiology},
  year    = {2021},
  doi     = {10.1148/radiol.2021203383},
  pmid    = {34032515},
  url     = {https://doi.org/10.1148/radiol.2021203383}
}

@article{lancaster2020-32238339,
  author  = {Lancaster, C. and Koychev, I. and Blane, J. and Chinner, A. and Wolters, L. and Hinds, C.},
  title   = {{Evaluating the Feasibility of Frequent Cognitive Assessment Using the Mezurio Smartphone App: Observational and Interview Study in Adults With Elevated Dementia Risk}},
  journal = {JMIR mHealth and uHealth},
  year    = {2020},
  doi     = {10.2196/16142},
  pmid    = {32238339},
  url     = {https://doi.org/10.2196/16142}
}

@article{zheng2019-31708854,
  author  = {Zheng, Y. and Guo, H. and Zhang, L. and Wu, J. and Li, Q. and Lv, F.},
  title   = {{Machine Learning-Based Framework for Differential Diagnosis Between Vascular Dementia and Alzheimer's Disease Using Structural MRI Features}},
  journal = {Frontiers in neurology},
  year    = {2019},
  doi     = {10.3389/fneur.2019.01097},
  pmid    = {31708854},
  url     = {https://doi.org/10.3389/fneur.2019.01097}
}

@article{basun2008-18413473,
  author  = {Basun, H. and Bogdanovic, N. and Ingelsson, M. and Almkvist, O. and Näslund, J. and Axelman, K. and Bird, T. D. and Nochlin, D. and others},
  title   = {{Clinical and neuropathological features of the arctic APP gene mutation causing early-onset Alzheimer disease}},
  journal = {Archives of neurology},
  year    = {2008},
  doi     = {10.1001/archneur.65.4.499},
  pmid    = {18413473},
  url     = {https://doi.org/10.1001/archneur.65.4.499}
}

@article{zhang2022-35123512,
  author  = {Zhang, S. S. and Zhu, L. and Peng, Y. and Zhang, L. and Chao, F. L. and Jiang, L. and Xiao, Q. and Liang, X. and others},
  title   = {{Long-term running exercise improves cognitive function and promotes microglial glucose metabolism and morphological plasticity in the hippocampus of APP/PS1 mice}},
  journal = {Journal of neuroinflammation},
  year    = {2022},
  doi     = {10.1186/s12974-022-02401-5},
  pmid    = {35123512},
  url     = {https://doi.org/10.1186/s12974-022-02401-5}
}

@article{vanderlip2026-42741980,
  author  = {Vanderlip, Casey R. and Stark, Craig E.L.},
  title   = {{Digital cognitive phenotyping enhances risk stratification in preclinical Alzheimer's disease}},
  journal = {Alzheimer s \& Dementia},
  year    = {2026},
  doi     = {10.1002/alz.71834},
  pmid    = {42741980},
  url     = {https://doi.org/10.1002/alz.71834}
}

@article{muksimova2025-40158456,
  author  = {Muksimova, Shakhnoza and Umirzakova, Sabina and Iskhakova, Nargiza and Khaĭtov, A and Cho, Young Im},
  title   = {{Advanced convolutional neural network with attention mechanism for Alzheimer's disease classification using MRI}},
  journal = {Computers in Biology and Medicine},
  year    = {2025},
  doi     = {10.1016/j.compbiomed.2025.110095},
  pmid    = {40158456},
  url     = {https://doi.org/10.1016/j.compbiomed.2025.110095}
}

@article{mousavi2025-40594827,
  author  = {Mousavi, Seyed Mohammad and Moulaei, Khadijeh and Ahmadian, Leila},
  title   = {{Classifying and diagnosing Alzheimer’s disease with deep learning using 6735 brain MRI images}},
  journal = {Scientific Reports},
  year    = {2025},
  doi     = {10.1038/s41598-025-08092-1},
  pmid    = {40594827},
  url     = {https://doi.org/10.1038/s41598-025-08092-1}
}

@article{moore2025-0d72c8cf,
  author  = {Moore, Dylan Edward and Tao, Songyun and Lucca, Emma Ricci-De and Tadin, Christina Sapp and Tadin, Dio and Morgan, Brian L. G. and Murnane, Elizabeth L.},
  title   = {{Family In The Loop: Enabling Family Involvement and Person-Centered Dementia Care at Long-Term Care Facilities with Collaborative AI Tools}},
  journal = {Proceedings of the ACM on Human-Computer Interaction},
  year    = {2025},
  doi     = {10.1145/3757599},
  url     = {https://doi.org/10.1145/3757599}
}

@article{gu2025-40009844,
  author  = {Gu, Z. N. and Liu, Shuang and Ma, Huijuan and Long, Yifan and Jiao, Xuehao and Gao, Xin and Du, Bingying and Bi, Xiaoying and others},
  title   = {{Estimation of Machine Learning–Based Models to Predict Dementia Risk in Patients With Atherosclerotic Cardiovascular Diseases: UK Biobank Study}},
  journal = {JMIR Aging},
  year    = {2025},
  doi     = {10.2196/64148},
  pmid    = {40009844},
  url     = {https://doi.org/10.2196/64148}
}

@article{gourdeau2026-41799879,
  author  = {Gourdeau, Christian and Gourdeau, Charles L. and Bernier, Patrick J. and Laforce, Robert Jr},
  title   = {{Enhanced diagnostic interpretation of the MoCA using machine learning}},
  journal = {Frontiers in Neuroscience},
  year    = {2026},
  doi     = {10.3389/fnins.2026.1679649},
  pmid    = {41799879},
  url     = {https://doi.org/10.3389/fnins.2026.1679649}
}

@article{sohn2025-41233889,
  author  = {Sohn, Minsung and Yang, Jungyeon and Lee, Junhyup and Choi, Daeyoung},
  title   = {{Predictive factors for dementia among older adults in South Korea: an interpretable machine learning analysis}},
  journal = {Alzheimer s Research \& Therapy},
  year    = {2025},
  doi     = {10.1186/s13195-025-01871-y},
  pmid    = {41233889},
  url     = {https://doi.org/10.1186/s13195-025-01871-y}
}

@article{li2025-40888555,
  author  = {Li, Yang and Wang, Jiao and Miao, Yuyang and Dunk, Michelle M. and Liu, Yan and Fang, Zhongze and Zhang, Qiang and Xu, Weili},
  title   = {{Association Between Plasma Metabolomic Profile and Machine Learning‐Based Brain Age}},
  journal = {Aging Cell},
  year    = {2025},
  doi     = {10.1111/acel.70208},
  pmid    = {40888555},
  url     = {https://doi.org/10.1111/acel.70208}
}

@article{goodwin2025-41117394,
  author  = {Goodwin, Grace J. and Cacho, Jorge Ramón Fonseca and Mehrzad, Sebastian and Cummings, Jeffrey L. and John, Samantha E.},
  title   = {{Classification of AD and bvFTD using neuropsychological and neuropsychiatric variables: a machine learning study}},
  journal = {Alzheimer s \& Dementia},
  year    = {2025},
  doi     = {10.1002/alz.70782},
  pmid    = {41117394},
  url     = {https://doi.org/10.1002/alz.70782}
}

@article{yang2026-41794745,
  author  = {Yang, Jingmei and Ding, Huitong and Amini, Samad and Hao, Boran and Karjadi, Cody and Au, Rhoda and Paschalidis, Ioannis Ch.},
  title   = {{Resource-stratified machine learning framework for cognitive status classification and mild cognitive impairment to dementia progression prediction}},
  journal = {Alzheimer s Research \& Therapy},
  year    = {2026},
  doi     = {10.1186/s13195-026-02006-7},
  pmid    = {41794745},
  url     = {https://doi.org/10.1186/s13195-026-02006-7}
}

@article{wen2026-41834991,
  author  = {Wen, Lulu and Zhang, Yifei and Nie, Yuting and Shen, Hui and Qin, Q and Qu, Miao},
  title   = {{Discriminative Plasma Lipidomic Signatures of Dementia with Lewy Bodies and Alzheimer’s Disease: A Targeted Mass Spectrometry and Machine Learning Approach}},
  journal = {Neuropsychiatric Disease and Treatment},
  year    = {2026},
  doi     = {10.2147/ndt.s561999},
  pmid    = {41834991},
  url     = {https://doi.org/10.2147/ndt.s561999}
}

@article{liu2025-40457220,
  author  = {Liu, Deyan and Tian, Yuge and Liu, Min and Yang, Shangjian},
  title   = {{Development of a neural network-based risk prediction model for mild cognitive impairment in older adults with functional disability}},
  journal = {BMC Public Health},
  year    = {2025},
  doi     = {10.1186/s12889-025-23310-1},
  pmid    = {40457220},
  url     = {https://doi.org/10.1186/s12889-025-23310-1}
}

@article{desimone2025-40718565,
  author  = {De Simone, Maria Stefania and Zabberoni, Silvia and da Costa, Alberto Luiz Cunha and Tenaglia, Erika and Tieri, Gaetano},
  title   = {{The effects of an immersive virtual reality and telemedicine-based multi-component intervention in individuals with subjective cognitive decline: study protocol of a randomized controlled trial}},
  journal = {Frontiers in Psychology},
  year    = {2025},
  doi     = {10.3389/fpsyg.2025.1591239},
  pmid    = {40718565},
  url     = {https://doi.org/10.3389/fpsyg.2025.1591239}
}

@article{karlsson2025-39985487,
  author  = {Karlsson, Linda and Vogel, Jacob and Arvidsson, Ida and Åström, Kalle and Strandberg, Olof and Seidlitz, Jakob and Bethlehem, Richard A I and Stomrud, Erik and others},
  title   = {{Machine learning prediction of tau-PET in Alzheimer's disease using plasma, MRI, and clinical data}},
  journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association},
  year    = {2025},
  doi     = {10.1002/alz.14600},
  pmid    = {39985487},
  url     = {https://doi.org/10.1002/alz.14600}
}

@article{kelly2023-37821485,
  author  = {Kelly, Jack and Moyeed, Rana and Carroll, Camille and Luo, Shouqing and Li, Xinzhong},
  title   = {{Blood biomarker-based classification study for neurodegenerative diseases}},
  journal = {Scientific reports},
  year    = {2023},
  doi     = {10.1038/s41598-023-43956-4},
  pmid    = {37821485},
  url     = {https://doi.org/10.1038/s41598-023-43956-4}
}

@article{benge2020-29661059,
  author  = {Benge, Jared F and Dinh, Kara L and Logue, Erin and Phenis, Richard and Dasse, Michelle N and Scullin, Michael K},
  title   = {{The smartphone in the memory clinic: A study of patient and care partner's utilisation habits}},
  journal = {Neuropsychological rehabilitation},
  year    = {2020},
  doi     = {10.1080/09602011.2018.1459307},
  pmid    = {29661059},
  url     = {https://doi.org/10.1080/09602011.2018.1459307}
}

@article{vangiau2019-31557888,
  author  = {Van Giau, Vo and Bagyinszky, Eva and Youn, Young Chul and An, Seong Soo A and Kim, SangYun},
  title   = {{APP, PSEN1, and PSEN2 Mutations in Asian Patients with Early-Onset Alzheimer Disease}},
  journal = {International journal of molecular sciences},
  year    = {2019},
  doi     = {10.3390/ijms20194757},
  pmid    = {31557888},
  url     = {https://doi.org/10.3390/ijms20194757}
}

@article{zhou2020-32579498,
  author  = {Zhou, Jiajia and Chen, Yi and Meng, Fanxia and Zhang, Kan and Liu, Xiaoyan and Peng, Guoping},
  title   = {{Presenilin 1 and APP Gene Mutations in Early-Onset AD Families from a Southeast Region of China}},
  journal = {Current Alzheimer research},
  year    = {2020},
  doi     = {10.2174/1567205017666200624195809},
  pmid    = {32579498},
  url     = {https://doi.org/10.2174/1567205017666200624195809}
}

@article{dumitrascu2024-39748801,
  author  = {Dumitrascu, Oana M and Li, Xin and Zhu, Wenhui and Woodruff, Bryan K and Nikolova, Simona and Sobczak, Jacob and Youssef, Amal and Saxena, Siddhant and others},
  title   = {{Color Fundus Photography and Deep Learning Applications in Alzheimer Disease}},
  journal = {Mayo Clinic proceedings. Digital health},
  year    = {2024},
  doi     = {10.1016/j.mcpdig.2024.08.005},
  pmid    = {39748801},
  url     = {https://doi.org/10.1016/j.mcpdig.2024.08.005}
}

@article{hasan2024-37674264,
  author  = {Hasan, Md Mahmudul and Phu, Jack and Sowmya, Arcot and Meijering, Erik and Kalloniatis, Michael},
  title   = {{Artificial intelligence in the diagnosis of glaucoma and neurodegenerative diseases}},
  journal = {Clinical \& experimental optometry},
  year    = {2024},
  doi     = {10.1080/08164622.2023.2235346},
  pmid    = {37674264},
  url     = {https://doi.org/10.1080/08164622.2023.2235346}
}

@article{lindauer2019-31127721,
  author  = {Lindauer, Allison and McKenzie, Glenise and LaFazia, David and McNeill, Loriann and Mincks, Kate and Spoden, Natasha and Myers, Marcella and Mattek, Nora and others},
  title   = {{Using Technology to Facilitate Fidelity Assessments: The Tele-STAR Caregiver Intervention}},
  journal = {Journal of medical Internet research},
  year    = {2019},
  doi     = {10.2196/13599},
  pmid    = {31127721},
  url     = {https://doi.org/10.2196/13599}
}

@article{harrell2014-24913209,
  author  = {Harrell, K. M. and Wilkins, S. S. and Connor, M. K. and Chodosh, J.},
  title   = {{Telemedicine and the evaluation of cognitive impairment: the additive value of neuropsychological assessment}},
  journal = {Journal of the American Medical Directors Association},
  year    = {2014},
  doi     = {10.1016/j.jamda.2014.04.015},
  pmid    = {24913209},
  url     = {https://doi.org/10.1016/j.jamda.2014.04.015}
}

@article{barton2011-22023458,
  author  = {Barton, C. and Morris, R. and Rothlind, J. and Yaffe, K.},
  title   = {{Video-telemedicine in a memory disorders clinic: evaluation and management of rural elders with cognitive impairment}},
  journal = {Telemedicine journal and e-health : the official journal of the American Telemedicine Association},
  year    = {2011},
  doi     = {10.1089/tmj.2011.0083},
  pmid    = {22023458},
  url     = {https://doi.org/10.1089/tmj.2011.0083}
}

@article{koo2019-30619948,
  author  = {Koo, B. M. and Vizer, L. M.},
  title   = {{Mobile Technology for Cognitive Assessment of Older Adults: A Scoping Review}},
  journal = {Innovation in aging},
  year    = {2019},
  doi     = {10.1093/geroni/igy038},
  pmid    = {30619948},
  url     = {https://doi.org/10.1093/geroni/igy038}
}

@article{khazaee2016-26363784,
  author  = {Khazaee, A. and Ebrahimzadeh, A. and Babajani-Feremi, A.},
  title   = {{Application of advanced machine learning methods on resting-state fMRI network for identification of mild cognitive impairment and Alzheimer's disease}},
  journal = {Brain imaging and behavior},
  year    = {2016},
  doi     = {10.1007/s11682-015-9448-7},
  pmid    = {26363784},
  url     = {https://doi.org/10.1007/s11682-015-9448-7}
}

@article{zhang2021-34531812,
  author  = {Zhang, X. and Lv, L. and Min, G. and Wang, Q. and Zhao, Y. and Li, Y.},
  title   = {{Overview of the Complex Figure Test and Its Clinical Application in Neuropsychiatric Disorders, Including Copying and Recall}},
  journal = {Frontiers in neurology},
  year    = {2021},
  doi     = {10.3389/fneur.2021.680474},
  pmid    = {34531812},
  url     = {https://doi.org/10.3389/fneur.2021.680474}
}

@article{akhterkhan2020-36037052,
  author  = {Akhter-Khan, S. C. and Au, R.},
  title   = {{Why Loneliness Interventions Are Unsuccessful: A Call for Precision Health}},
  journal = {Advances in geriatric medicine and research},
  year    = {2020},
  doi     = {10.20900/agmr20200016},
  pmid    = {36037052},
  url     = {https://doi.org/10.20900/agmr20200016}
}

@article{lee2022-36231707,
  author  = {Lee, H. and Lim, J. A. and Nam, H. K.},
  title   = {{Effect of a Digital Literacy Program on Older Adults' Digital Social Behavior: A Quasi-Experimental Study}},
  journal = {International journal of environmental research and public health},
  year    = {2022},
  doi     = {10.3390/ijerph191912404},
  pmid    = {36231707},
  url     = {https://doi.org/10.3390/ijerph191912404}
}

@article{bellomo2021-33867925,
  author  = {Bellomo, G. and Indaco, A. and Chiasserini, D. and Maderna, E. and Paolini Paoletti, F. and Gaetani, L. and Paciotti, S. and Petricciuolo, M. and others},
  title   = {{Machine Learning Driven Profiling of Cerebrospinal Fluid Core Biomarkers in Alzheimer's Disease and Other Neurological Disorders}},
  journal = {Frontiers in neuroscience},
  year    = {2021},
  doi     = {10.3389/fnins.2021.647783},
  pmid    = {33867925},
  url     = {https://doi.org/10.3389/fnins.2021.647783}
}

@article{cavedoni2020-32848660,
  author  = {Cavedoni, S. and Chirico, A. and Pedroli, E. and Cipresso, P. and Riva, G.},
  title   = {{Digital Biomarkers for the Early Detection of Mild Cognitive Impairment: Artificial Intelligence Meets Virtual Reality}},
  journal = {Frontiers in human neuroscience},
  year    = {2020},
  doi     = {10.3389/fnhum.2020.00245},
  pmid    = {32848660},
  url     = {https://doi.org/10.3389/fnhum.2020.00245}
}

@article{kang2019-31752864,
  author  = {Kang, M. J. and Kim, S. Y. and Na, D. L. and Kim, B. C. and Yang, D. W. and Kim, E. J. and Na, H. R. and Han, H. J. and others},
  title   = {{Prediction of cognitive impairment via deep learning trained with multi-center neuropsychological test data}},
  journal = {BMC medical informatics and decision making},
  year    = {2019},
  doi     = {10.1186/s12911-019-0974-x},
  pmid    = {31752864},
  url     = {https://doi.org/10.1186/s12911-019-0974-x}
}

@article{karaglani2020-32962113,
  author  = {Karaglani, M. and Gourlia, K. and Tsamardinos, I. and Chatzaki, E.},
  title   = {{Accurate Blood-Based Diagnostic Biosignatures for Alzheimer's Disease via Automated Machine Learning}},
  journal = {Journal of clinical medicine},
  year    = {2020},
  doi     = {10.3390/jcm9093016},
  pmid    = {32962113},
  url     = {https://doi.org/10.3390/jcm9093016}
}

@article{farrer1997-9189907,
  author  = {Farrer, M. J. and Crayton, L. and Davies, G. E. and Oliver, C. and Powell, J. and Holland, A. J. and Kessling, A. M.},
  title   = {{Allelic variability in D21S11, but not in APP or APOE, is associated with cognitive decline in Down syndrome}},
  journal = {Neuroreport},
  year    = {1997},
  doi     = {10.1097/00001756-199705060-00018},
  pmid    = {9189907},
  url     = {https://doi.org/10.1097/00001756-199705060-00018}
}

@article{rubenstein2025-41105592,
  author  = {Rubenstein, E. and Tewolde, S. and Michals, A. and Fortea, J. and Jimenez, M. P. and Skotko, B. G. and Tripodis, Y. and Weuve, J. and others},
  title   = {{Novel predictors of Alzheimer's disease in Down syndrome identified using machine learning}},
  journal = {Journal of Alzheimer's disease : JAD},
  year    = {2025},
  doi     = {10.1177/13872877251385423},
  pmid    = {41105592},
  url     = {https://doi.org/10.1177/13872877251385423}
}