% alzhub.org library filter % Source: https://alzhub.org/research?category=assessment&about=biomarkers % 86 entries, in the order the page lists them. Built from alzhub.org's own records. % 0 entries have no readable author in the source record and carry no author field. @article{ng2019-30634650, author = {Ng, T. K. S. and Ho, C. S. H. and Tam, W. W. S. and Kua, E. H. and Ho, R. C.}, title = {{Decreased Serum Brain-Derived Neurotrophic Factor (BDNF) Levels in Patients with Alzheimer's Disease (AD): A Systematic Review and Meta-Analysis}}, journal = {International journal of molecular sciences}, year = {2019}, doi = {10.3390/ijms20020257}, pmid = {30634650}, url = {https://doi.org/10.3390/ijms20020257} } @article{amirbehghadami2026-41730560, author = {Amir-Behghadami, M. and Gholipour, K. and Mohammadzadeh, Z.}, title = {{Vocal biomarkers for geriatric health assessment: a scoping review protocol}}, journal = {BMJ open}, year = {2026}, doi = {10.1136/bmjopen-2025-109480}, pmid = {41730560}, url = {https://doi.org/10.1136/bmjopen-2025-109480} } @article{blennow2019-31836810, author = {Blennow, K. and Shaw, L. M. and Stomrud, E. and Mattsson, N. and Toledo, J. B. and Buck, K. and Wahl, S. and Eichenlaub, U. and others}, title = {{Predicting clinical decline and conversion to Alzheimer's disease or dementia using novel Elecsys Aβ(1-42), pTau and tTau CSF immunoassays}}, journal = {Scientific reports}, year = {2019}, doi = {10.1038/s41598-019-54204-z}, pmid = {31836810}, url = {https://doi.org/10.1038/s41598-019-54204-z} } @article{harms2022-35719134, author = {Harms, R. L. and Ferrari, A. and Meier, I. B. and Martinkova, J. and Santus, E. and Marino, N. and Cirillo, D. and Mellino, S. and others}, title = {{Digital biomarkers and sex impacts in Alzheimer's disease management - potential utility for innovative 3P medicine approach}}, journal = {The EPMA journal}, year = {2022}, doi = {10.1007/s13167-022-00284-3}, pmid = {35719134}, url = {https://doi.org/10.1007/s13167-022-00284-3} } @article{corona2026-41737720, author = {Corona, Christopher Gonzalez and Lopera, Paula Ospina and Rowe, Meredith C and Vila-Castelar, Clara and Giudicessi, Averi and Malotaux, Vincent and He, Bing and Tristão-Pereira, Catarina and others}, title = {{Web-based LAS-FNAME and blood biomarkers in autosomal dominant Alzheimer's disease}}, journal = {Alzheimer's \& dementia (Amsterdam, Netherlands)}, year = {2026}, doi = {10.1002/dad2.70289}, pmid = {41737720}, url = {https://doi.org/10.1002/dad2.70289} } @article{tideman2025-40954312, author = {Tideman, P. and Karlsson, L. and Strandberg, O. and Calling, S. and Smith, R. and Midlöv, P. and Verghese, P. B. and Braunstein, J. B. and others}, title = {{Primary care detection of Alzheimer's disease using a self-administered digital cognitive test and blood biomarkers}}, journal = {Nature medicine}, year = {2025}, doi = {10.1038/s41591-025-03965-4}, pmid = {40954312}, url = {https://doi.org/10.1038/s41591-025-03965-4} } @article{snider2009-19433664, author = {Snider, B. J. and Fagan, A. M. and Roe, C. and Shah, A. R. and Grant, E. A. and Xiong, C. and Morris, J. C. and Holtzman, D. M.}, title = {{Cerebrospinal fluid biomarkers and rate of cognitive decline in very mild dementia of the Alzheimer type}}, journal = {Archives of neurology}, year = {2009}, doi = {10.1001/archneurol.2009.55}, pmid = {19433664}, url = {https://doi.org/10.1001/archneurol.2009.55} } @article{tsoy2024-38224278, author = {Tsoy, E. and La Joie, R. and VandeVrede, L. and Rojas, J. C. and Yballa, C. and Chan, B. and Lago, A. L. and Rodriguez, A. M. and others}, title = {{Scalable plasma and digital cognitive markers for diagnosis and prognosis of Alzheimer's disease and related dementias}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2024}, doi = {10.1002/alz.13686}, pmid = {38224278}, url = {https://doi.org/10.1002/alz.13686} } @article{lewczuk2018-30055655, author = {Lewczuk, P. and Ermann, N. and Andreasson, U. and Schultheis, C. and Podhorna, J. and Spitzer, P. and Maler, J. M. and Kornhuber, J. and others}, title = {{Plasma neurofilament light as a potential biomarker of neurodegeneration in Alzheimer's disease}}, journal = {Alzheimer's research \& therapy}, year = {2018}, doi = {10.1186/s13195-018-0404-9}, pmid = {30055655}, url = {https://doi.org/10.1186/s13195-018-0404-9} } @article{oh2025-40755953, author = {Oh, Chorong and Park, Min Sook}, title = {{Unveiling 30 years of research on speech biomarker of dementia using text mining}}, journal = {Digital health}, year = {2025}, doi = {10.1177/20552076251360901}, pmid = {40755953}, url = {https://doi.org/10.1177/20552076251360901} } @article{jannati2025-41382170, author = {Jannati, A. and Thompson, K. and Toro-Serey, C. and Gomes-Osman, J. and Banks, R. E. and Higgins, C. and Showalter, J. and Bates, D. and others}, title = {{Concurrent detection of cognitive impairment and amyloid positivity with a multimodal machine learning-enabled digital cognitive assessment}}, journal = {Alzheimer's research \& therapy}, year = {2025}, doi = {10.1186/s13195-025-01913-5}, pmid = {41382170}, url = {https://doi.org/10.1186/s13195-025-01913-5} } @article{corbett2026-42091863, author = {Corbett, A. and Sander-Long, M. and Ashton, N. J. and Huber, H. and Vavra, J. and Braun-Wohlfahrt, L. S. and Zetterberg, H. and Montoliu-Gaya, L. and others}, title = {{Alzheimer's Disease blood biomarkers measured through remote capillary sampling correlate with cognition in older adults}}, journal = {Nature communications}, year = {2026}, doi = {10.1038/s41467-026-71448-2}, pmid = {42091863}, url = {https://doi.org/10.1038/s41467-026-71448-2} } @article{babulal2016-27426238, author = {Babulal, G. M. and Ghoshal, N. and Head, D. and Vernon, E. K. and Holtzman, D. M. and Benzinger, T. L. S. and Fagan, A. M. and Morris, J. C. and others}, title = {{Mood Changes in Cognitively Normal Older Adults are Linked to Alzheimer Disease Biomarker Levels}}, journal = {The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry}, year = {2016}, doi = {10.1016/j.jagp.2016.04.004}, pmid = {27426238}, url = {https://doi.org/10.1016/j.jagp.2016.04.004} } @article{erickson2026-41557565, author = {Erickson, Pontus and Skillbäck, Tobias Borgh and Kern, Silke and Skoog, I. and Jönsson, Linus and Andréasson, Ulf and Blennow, Kaj and Eriksdotter, Maria and others}, title = {{Limited Diagnostic Performance of Cerebrospinal Fluid Glial Fibrillary Acidic Protein in Dementia}}, journal = {Dementia and Geriatric Cognitive Disorders}, year = {2026}, doi = {10.1159/000550601}, pmid = {41557565}, url = {https://doi.org/10.1159/000550601} } @article{heller2020-31937580, author = {Heller, C. and Foiani, M. S. and Moore, K. and Convery, R. and Bocchetta, M. and Neason, M. and Cash, D. M. and Thomas, D. and others}, title = {{Plasma glial fibrillary acidic protein is raised in progranulin-associated frontotemporal dementia}}, journal = {Journal of neurology, neurosurgery, and psychiatry}, year = {2020}, doi = {10.1136/jnnp-2019-321954}, pmid = {31937580}, url = {https://doi.org/10.1136/jnnp-2019-321954} } @article{chan2025-41137616, author = {Chan, Diane and de Weck, Gabrielle and Jackson, Brennan and Suk, Ho‐Jun and Milman, Noah Pollak and Kitchener, Erin G. and Avalos, Vanesa S. Fernandez and Quay, M. J. and others}, title = {{Gamma sensory stimulation in mild Alzheimer's dementia: An open‐label extension study}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz.70792}, pmid = {41137616}, url = {https://doi.org/10.1002/alz.70792} } @article{vanderlip2024-39239893, author = {Vanderlip, C. R. and Lee, M. D. and Stark, C. E. L.}, title = {{Cognitive modeling of the Mnemonic Similarity Task as a digital biomarker for Alzheimer's disease}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2024}, doi = {10.1002/alz.14163}, pmid = {39239893}, url = {https://doi.org/10.1002/alz.14163} } @article{wang2025-41121436, author = {Wang, Jin-Tao and Zhi, Nan and Xu, Gang and Geng, Jie-Li and Xiao, Jin-Wen and Li, Hai-Xia and Li, Jian-Ping and Xie, Xin-Yi and others}, title = {{Speech digital biomarker combined with fluid biomarkers predict cognitive impairment through machine learning}}, journal = {Alzheimer's research \& therapy}, year = {2025}, doi = {10.1186/s13195-025-01877-6}, pmid = {41121436}, url = {https://doi.org/10.1186/s13195-025-01877-6} } @article{jutten2025-40836942, author = {Jutten, R. J. and Burling, J. E. and Slade, E. and Thompson, J. C. and Fu, J. F. and Birkenbihl, C. and Properzi, M. J. and Marshall, G. A. and others}, title = {{The Mobile Toolbox for remote, self-administered cognitive assessment in older adults: associations with in-clinic cognitive testing and Alzheimer's disease biomarkers}}, journal = {Alzheimer's \& dementia (Amsterdam, Netherlands)}, year = {2025}, doi = {10.1002/dad2.70160}, pmid = {40836942}, url = {https://doi.org/10.1002/dad2.70160} } @article{mielke2011-21841258, author = {Mielke, M. M. and Haughey, N. J. and Bandaru, V. V. and Weinberg, D. D. and Darby, E. and Zaidi, N. and Pavlik, V. and Doody, R. S. and others}, title = {{Plasma sphingomyelins are associated with cognitive progression in Alzheimer's disease}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2011}, doi = {10.3233/jad-2011-110405}, pmid = {21841258}, url = {https://doi.org/10.3233/jad-2011-110405} } @article{fjell2010-20147537, author = {Fjell, A. M. and Walhovd, K. B. and Fennema-Notestine, C. and McEvoy, L. K. and Hagler, D. J. and Holland, D. and Brewer, J. B. and Dale, A. M. and others}, title = {{CSF biomarkers in prediction of cerebral and clinical change in mild cognitive impairment and Alzheimer's disease}}, journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience}, year = {2010}, doi = {10.1523/jneurosci.3785-09.2010}, pmid = {20147537}, url = {https://doi.org/10.1523/jneurosci.3785-09.2010} } @article{quadalti2021-34635674, author = {Quadalti, C. and Calandra-Buonaura, G. and Baiardi, S. and Mastrangelo, A. and Rossi, M. and Zenesini, C. and Giannini, G. and Candelise, N. and others}, title = {{Neurofilament light chain and α-synuclein RT-QuIC as differential diagnostic biomarkers in parkinsonisms and related syndromes}}, journal = {NPJ Parkinson's disease}, year = {2021}, doi = {10.1038/s41531-021-00232-4}, pmid = {34635674}, url = {https://doi.org/10.1038/s41531-021-00232-4} } @article{toniolo2024-38623387, author = {Toniolo, S. and Zhao, S. and Scholcz, A. and Amein, B. and Ganse-Dumrath, A. and Heslegrave, A. J. and Thompson, S. and Manohar, S. and others}, title = {{Relationship of plasma biomarkers to digital cognitive tests in Alzheimer's disease}}, journal = {Alzheimer's \& dementia (Amsterdam, Netherlands)}, year = {2024}, doi = {10.1002/dad2.12590}, pmid = {38623387}, url = {https://doi.org/10.1002/dad2.12590} } @article{bruno2024-39258756, author = {Bruno, Davide and Jauregi-Zinkunegi, Ainara and Bock, Jason R and {Alzheimer's Disease Neuroimaging Initiative}}, title = {{Predicting CDR status over 36 months with a recall-based digital cognitive biomarker}}, journal = {Alzheimer's \& dementia : the journal of the Alzheimer's Association}, year = {2024}, doi = {10.1002/alz.14213}, pmid = {39258756}, url = {https://doi.org/10.1002/alz.14213} } @article{fonseca2024-39445343, author = {Fonseca, Luciana Mascarenhas and Beeri, Michal Schnaider and Hawks, Zoë W and Jung, Lanee and Cleveland, Michael and Delgado, Nikki and Bulger, Jane and Grinspoon, Elizabeth and others}, title = {{ATN blood biomarkers are related to digital cognitive assessment in type 1 diabetes}}, journal = {Alzheimer's \& dementia (Amsterdam, Netherlands)}, year = {2024}, doi = {10.1002/dad2.70029}, pmid = {39445343}, url = {https://doi.org/10.1002/dad2.70029} } @article{wang2024-38476660, author = {Wang, Jing and Zhou, Zheping and Cheng, Shanshan and Zhou, Li and Sun, Xiaoou and Song, Ziyang and Wu, Zhiwei and Lu, Jinhua and others}, title = {{Dual-task turn velocity - a novel digital biomarker for mild cognitive impairment and dementia}}, journal = {Frontiers in aging neuroscience}, year = {2024}, doi = {10.3389/fnagi.2024.1304265}, pmid = {38476660}, url = {https://doi.org/10.3389/fnagi.2024.1304265} } @article{tikkanen2025-41143873, author = {Tikkanen, Veera and Paajanen, Teemu I and Heikkinen, Anna-Leena and Solje, Eino and Katisko, Kasper and Kokkola, Tarja and Kärkkäinen, Sari and Herukka, Sanna-Kaisa and others}, title = {{Combining a computerized cognitive test with serum biomarkers improves detection of early-onset neurodegenerative disorders}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2025}, doi = {10.1177/13872877251389224}, pmid = {41143873}, url = {https://doi.org/10.1177/13872877251389224} } @article{lemstra2017-27794030, author = {Lemstra, A. W. and de Beer, M. H. and Teunissen, C. E. and Schreuder, C. and Scheltens, P. and van der Flier, W. M. and Sikkes, S. A.}, title = {{Concomitant AD pathology affects clinical manifestation and survival in dementia with Lewy bodies}}, journal = {Journal of neurology, neurosurgery, and psychiatry}, year = {2017}, doi = {10.1136/jnnp-2016-313775}, pmid = {27794030}, url = {https://doi.org/10.1136/jnnp-2016-313775} } @article{lin2026-41212661, author = {Lin, Lishan and Huang, Huaxin and Zhang, Ya and Li, Fenglin and Yang, Huiming and Su, Fengjuan and Lei, Jiang and Bergeron, Michael F and others}, title = {{Utility of a contemporary digital cognitive-motor biomarker in Huntington's and Parkinson's diseases}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2026}, doi = {10.1177/13872877251393639}, pmid = {41212661}, url = {https://doi.org/10.1177/13872877251393639} } @article{gustafson2007-17098843, author = {Gustafson, D. R. and Skoog, I. and Rosengren, L. and Zetterberg, H. and Blennow, K.}, title = {{Cerebrospinal fluid beta-amyloid 1-42 concentration may predict cognitive decline in older women}}, journal = {Journal of neurology, neurosurgery, and psychiatry}, year = {2007}, doi = {10.1136/jnnp.2006.100529}, pmid = {17098843}, url = {https://doi.org/10.1136/jnnp.2006.100529} } @article{chen2025-40618175, author = {Chen, W. and Liao, Y. and Shi, X. and Su, F. and Kong, H. and Fang, Y. and Zheng, Y. and Zhou, J. and others}, title = {{Predicting brain amyloid load with digital and blood-based biomarkers}}, journal = {Alzheimer's research \& therapy}, year = {2025}, doi = {10.1186/s13195-025-01801-y}, pmid = {40618175}, url = {https://doi.org/10.1186/s13195-025-01801-y} } @article{tully2003-12654166, author = {Tully, A. M. and Roche, H. M. and Doyle, R. and Fallon, C. and Bruce, I. and Lawlor, B. and Coakley, D. and Gibney, M. J.}, title = {{Low serum cholesteryl ester-docosahexaenoic acid levels in Alzheimer's disease: a case-control study}}, journal = {The British journal of nutrition}, year = {2003}, doi = {10.1079/bjn2002804}, pmid = {12654166}, url = {https://doi.org/10.1079/bjn2002804} } @article{tsoy2021-33557905, author = {Tsoy, E. and Strom, A. and Iaccarino, L. and Erlhoff, S. J. and Goode, C. A. and Rodriguez, A. M. and Rabinovici, G. D. and Miller, B. L. and others}, title = {{Detecting Alzheimer's disease biomarkers with a brief tablet-based cognitive battery: sensitivity to Aβ and tau PET}}, journal = {Alzheimer's research \& therapy}, year = {2021}, doi = {10.1186/s13195-021-00776-w}, pmid = {33557905}, url = {https://doi.org/10.1186/s13195-021-00776-w} } @article{cay2024-38219728, author = {Cay, G. and Pfeifer, V. A. and Lee, M. and Rouzi, M. D. and Nunes, A. S. and El-Refaei, N. and Momin, A. S. and Atique, M. M. U. and others}, title = {{Harnessing Speech-Derived Digital Biomarkers to Detect and Quantify Cognitive Decline Severity in Older Adults}}, journal = {Gerontology}, year = {2024}, doi = {10.1159/000536250}, pmid = {38219728}, url = {https://doi.org/10.1159/000536250} } @article{sankhe2026-41521126, author = {Sankhe, Krushnaa and Ruthirakuhan, Myuri T. and Andreazza, Ana C. and Brawman‐Mintzer, Olga and Craft, Suzanne and Herrmann, Nathan and Ismail, Zahinoor and Lerner, Alan J. and others}, title = {{Peripheral biomarkers associated with apathy and predicting response to methylphenidate: Secondary analysis of the Apathy in Dementia Methylphenidate Trial 2 (ADMET2) study}}, journal = {International Psychogeriatrics}, year = {2026}, doi = {10.1016/j.inpsyc.2025.100181}, pmid = {41521126}, url = {https://doi.org/10.1016/j.inpsyc.2025.100181} } @article{ottoy2019-30927601, author = {Ottoy, J. and Niemantsverdriet, E. and Verhaeghe, J. and De Roeck, E. and Struyfs, H. and Somers, C. and Wyffels, L. and Ceyssens, S. and others}, title = {{Association of short-term cognitive decline and MCI-to-AD dementia conversion with CSF, MRI, amyloid- and 18F-FDG-PET imaging}}, journal = {NeuroImage. Clinical}, year = {2019}, doi = {10.1016/j.nicl.2019.101771}, pmid = {30927601}, url = {https://doi.org/10.1016/j.nicl.2019.101771} } @article{wagshal2015-24899730, author = {Wagshal, D. and Sankaranarayanan, S. and Guss, V. and Hall, T. and Berisha, F. and Lobach, I. and Karydas, A. and Voltarelli, L. and others}, title = {{Divergent CSF τ alterations in two common tauopathies: Alzheimer's disease and progressive supranuclear palsy}}, journal = {Journal of neurology, neurosurgery, and psychiatry}, year = {2015}, doi = {10.1136/jnnp-2014-308004}, pmid = {24899730}, url = {https://doi.org/10.1136/jnnp-2014-308004} } @article{perezmillan2025-39934339, author = {Pérez‐Millan, Agnès and Estrada, Uma Maria Lal-Trehan and Falgàs, Neus and Guillén, Núria and Borrego‐Écija, Sergi and Juncà‐Parella, Jordi and Bosch, Beatríz and Tort‐Merino, Adrià and others}, title = {{The Cortical Asymmetry Index for subtyping dementia patients}}, journal = {European Radiology}, year = {2025}, doi = {10.1007/s00330-025-11400-y}, pmid = {39934339}, url = {https://doi.org/10.1007/s00330-025-11400-y} } @article{troger2022-36466952, author = {Tröger, J. and Baykara, E. and Zhao, J. and Ter Huurne, D. and Possemis, N. and Mallick, E. and Schäfer, S. and Schwed, L. and others}, title = {{Validation of the Remote Automated ki:e Speech Biomarker for Cognition in Mild Cognitive Impairment: Verification and Validation following DiME V3 Framework}}, journal = {Digital biomarkers}, year = {2022}, doi = {10.1159/000526471}, pmid = {36466952}, url = {https://doi.org/10.1159/000526471} } @article{fogel2021-34526957, author = {Fogel, H. and Levy-Lamdan, O. and Zifman, N. and Hiller, T. and Efrati, S. and Suzin, G. and Hack, D. C. and Dolev, I. and others}, title = {{Brain Network Integrity Changes in Subjective Cognitive Decline: A Possible Physiological Biomarker of Dementia}}, journal = {Frontiers in neurology}, year = {2021}, doi = {10.3389/fneur.2021.699014}, pmid = {34526957}, url = {https://doi.org/10.3389/fneur.2021.699014} } @article{osse2026-41716297, author = {Osse, A. M. L. and Zhou, Y. and Kinney, J. W. and Hooyman, A. and Sengupta, A. and Fonseca, J. and Burstein, A. H. and Owen, M. and others}, title = {{Biomarkers in Alzheimer's disease clinical trials: 2025}}, journal = {Alzheimer's \& dementia (New York, N. Y.)}, year = {2026}, doi = {10.1002/trc2.70217}, pmid = {41716297}, url = {https://doi.org/10.1002/trc2.70217} } @article{ohrfelt2009-19022350, author = {Ohrfelt, A. and Grognet, P. and Andreasen, N. and Wallin, A. and Vanmechelen, E. and Blennow, K. and Zetterberg, H.}, title = {{Cerebrospinal fluid alpha-synuclein in neurodegenerative disorders-a marker of synapse loss?}}, journal = {Neuroscience letters}, year = {2009}, doi = {10.1016/j.neulet.2008.11.015}, pmid = {19022350}, url = {https://doi.org/10.1016/j.neulet.2008.11.015} } @article{green1999-10025576, author = {Green, A. J. and Harvey, R. J. and Thompson, E. J. and Rossor, M. N.}, title = {{Increased tau in the cerebrospinal fluid of patients with frontotemporal dementia and Alzheimer's disease}}, journal = {Neuroscience letters}, year = {1999}, doi = {10.1016/s0304-3940(98)00904-5}, pmid = {10025576}, url = {https://doi.org/10.1016/s0304-3940(98)00904-5} } @article{gonzalez2025-39994784, author = {González, Alba Cervantes and Goossens, Julie and Campuzano, E. Vera and Sala, Isabel and Sánchez‐Saudinós, María Belén and Rodríguez‐Baz, Íñigo and Lidón, Laia and Perlaza, Danna and others}, title = {{Evaluation of cerebrospinal fluid levels of VAMP-2 and SNAP-25 in a dementia with Lewy bodies clinical cohort stratified by Alzheimer’s pathophysiological biomarkers}}, journal = {Alzheimer s Research \& Therapy}, year = {2025}, doi = {10.1186/s13195-025-01685-y}, pmid = {39994784}, url = {https://doi.org/10.1186/s13195-025-01685-y} } @article{liguori2015-25121572, author = {Liguori, C. and Stefani, A. and Sancesario, G. and Sancesario, G. M. and Marciani, M. G. and Pierantozzi, M.}, title = {{CSF lactate levels, τ proteins, cognitive decline: a dynamic relationship in Alzheimer's disease}}, journal = {Journal of neurology, neurosurgery, and psychiatry}, year = {2015}, doi = {10.1136/jnnp-2014-308577}, pmid = {25121572}, url = {https://doi.org/10.1136/jnnp-2014-308577} } @article{wilks2021-35037593, author = {Wilks, H. and Aschenbrenner, A. J. and Gordon, B. A. and Balota, D. A. and Fagan, A. M. and Musiek, E. and Balls-Berry, J. and Benzinger, T. L. S. and others}, title = {{Sharper in the morning: Cognitive time of day effects revealed with high-frequency smartphone testing}}, journal = {Journal of clinical and experimental neuropsychology}, year = {2021}, doi = {10.1080/13803395.2021.2009447}, pmid = {35037593}, url = {https://doi.org/10.1080/13803395.2021.2009447} } @article{snyder2018-32095757, author = {Snyder, C. W. and Dorsey, E. R. and Atreja, A.}, title = {{The Best Digital Biomarkers Papers of 2017}}, journal = {Digital biomarkers}, year = {2018}, doi = {10.1159/000489224}, pmid = {32095757}, url = {https://doi.org/10.1159/000489224} } @article{soldan2016-27903332, author = {Soldan, A. and Pettigrew, C. and Moghekar, A. and Albert, M. and {BIOCARD Research Team}}, title = {{Computerized Cognitive Tests Are Associated with Biomarkers of Alzheimer's Disease in Cognitively Normal Individuals 10 Years Prior}}, journal = {Journal of the International Neuropsychological Society : JINS}, year = {2016}, doi = {10.1017/s1355617716000722}, pmid = {27903332}, url = {https://doi.org/10.1017/s1355617716000722} } @article{bock2021-33569557, author = {Bock, JR. and Hara, J. and Fortier, D. and Lee, M. D. and Petersen, R. C. and Shankle, W. R.}, title = {{Application of Digital Cognitive Biomarkers for Alzheimer's Disease: Identifying Cognitive Process Changes and Impending Cognitive Decline}}, journal = {The journal of prevention of Alzheimer's disease}, year = {2021}, doi = {10.14283/jpad.2020.63}, pmid = {33569557}, url = {https://doi.org/10.14283/jpad.2020.63} } @article{giacomini2026-41665706, author = {Giacomini, P. S. and Voss, P. and Devonshire, V. and Schneider, R. and Macaron, G. and Hussein, S. and Blanchette, F. and É, de Villers-Sidani}, title = {{Eye tracking as a digital biomarker in neurodegenerative diseases}}, journal = {Journal of neurology}, year = {2026}, doi = {10.1007/s00415-026-13666-8}, pmid = {41665706}, url = {https://doi.org/10.1007/s00415-026-13666-8} } @article{laske2006-16362629, author = {Laske, C. and Stransky, E. and Leyhe, T. and Eschweiler, G. W. and Wittorf, A. and Richartz, E. and Bartels, M. and Buchkremer, G. and others}, title = {{Stage-dependent BDNF serum concentrations in Alzheimer's disease}}, journal = {Journal of neural transmission (Vienna, Austria : 1996)}, year = {2006}, doi = {10.1007/s00702-005-0397-y}, pmid = {16362629}, url = {https://doi.org/10.1007/s00702-005-0397-y} } @article{honey2025-41339948, author = {Honey, Madison I. J. and van Maurik, Ingrid S. and van Harten, Argonde C. and Gouda, Mariam and van Leeuwenstijn, Mardou S. S. A. and Mank, Arenda and Trieu, Calvin and Bouteloup, Vincent and others}, title = {{Individualized prediction of clinical progression to dementia using plasma biomarkers in non-demented elderly}}, journal = {Alzheimer s Research \& Therapy}, year = {2025}, doi = {10.1186/s13195-025-01925-1}, pmid = {41339948}, url = {https://doi.org/10.1186/s13195-025-01925-1} } @article{barba2025-40571405, author = {Barba, Lorenzo and Bellomo, Giovanni and Alcolea, Daniel Andres and Wojdała, Anna Lidia and Gaetani, Lorenzo and Fortea, Juan and Abu‐Rumeileh, Samir and Lleó, Alberto and others}, title = {{Serum level changes of the synaptic marker beta-synuclein in Alzheimer’s disease continuum and other dementias}}, journal = {Journal of Neurology Neurosurgery \& Psychiatry}, year = {2025}, doi = {10.1136/jnnp-2025-336189}, pmid = {40571405}, url = {https://doi.org/10.1136/jnnp-2025-336189} } @article{peskind2001-11578776, author = {Peskind, E. R. and Griffin, W. S. and Akama, K. T. and Raskind, M. A. and Van Eldik, L. J.}, title = {{Cerebrospinal fluid S100B is elevated in the earlier stages of Alzheimer's disease}}, journal = {Neurochemistry international}, year = {2001}, doi = {10.1016/s0197-0186(01)00048-1}, pmid = {11578776}, url = {https://doi.org/10.1016/s0197-0186(01)00048-1} } @article{wu2021-35005204, author = {Wu, Chao-Yi and Beattie, Zachary and Mattek, Nora and Sharma, Nicole and Kaye, Jeffrey and Dodge, Hiroko H}, title = {{Reproducibility and replicability of high-frequency, in-home digital biomarkers in reducing sample sizes for clinical trials}}, journal = {Alzheimer's \& dementia (New York, N. Y.)}, year = {2021}, doi = {10.1002/trc2.12220}, pmid = {35005204}, url = {https://doi.org/10.1002/trc2.12220} } @article{mekulu2025-41446371, author = {Mekulu, K. and Aqlan, F. and Yang, H.}, title = {{Character-level linguistic biomarkers for precision assessment of cognitive decline: a symbolic recurrence approach}}, journal = {Frontiers in aging neuroscience}, year = {2025}, doi = {10.3389/fnagi.2025.1681124}, pmid = {41446371}, url = {https://doi.org/10.3389/fnagi.2025.1681124} } @article{tarnanas2025-41602207, author = {Tarnanas, I. and Seixas, A. and Wyss, M. and Vlamos, P. and Çöltekin, A.}, title = {{Merging multimodal digital biomarkers into "Digital Neuro Fingerprints" for precision neurology in dementias: the promise of the right treatment for the right patient at the right time in the age of AI}}, journal = {Frontiers in digital health}, year = {2025}, doi = {10.3389/fdgth.2025.1727707}, pmid = {41602207}, url = {https://doi.org/10.3389/fdgth.2025.1727707} } @article{chaves2010-20105309, author = {Chaves, M. L. and Camozzato, A. L. and Ferreira, E. D. and Piazenski, I. and Kochhann, R. and Dall'Igna, O. and Mazzini, G. S. and Souza, D. O. and others}, title = {{Serum levels of S100B and NSE proteins in Alzheimer's disease patients}}, journal = {Journal of neuroinflammation}, year = {2010}, doi = {10.1186/1742-2094-7-6}, pmid = {20105309}, url = {https://doi.org/10.1186/1742-2094-7-6} } @article{racine2016-27589532, author = {Racine, A. M. and Clark, L. R. and Berman, S. E. and Koscik, R. L. and Mueller, K. D. and Norton, D. and Nicholas, C. R. and Blennow, K. and others}, title = {{Associations between Performance on an Abbreviated CogState Battery, Other Measures of Cognitive Function, and Biomarkers in People at Risk for Alzheimer's Disease}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2016}, doi = {10.3233/jad-160528}, pmid = {27589532}, url = {https://doi.org/10.3233/jad-160528} } @article{schafer2024-38427201, author = {Schäfer, Simona and Herrmann, Janna and Tovar, Sol and Linz, Nicklas and Tröger, Johannes}, title = {{Speech-Based Digital Biomarkers for Alzheimer's Research}}, journal = {Methods in molecular biology (Clifton, N.J.)}, year = {2024}, doi = {10.1007/978-1-0716-3774-6_18}, pmid = {38427201}, url = {https://doi.org/10.1007/978-1-0716-3774-6_18} } @article{perneczky2024-38427184, author = {Perneczky, Robert and Hansen, Niels and Hofmann, Anna and Laske, Christoph and Priller, Josef and Grimmer, Timo and Frölich, Lutz and Düzel, Emrah and others}, title = {{Blood-Based Biomarkers for Early Alzheimer's Disease Diagnosis in Real-World Settings}}, journal = {Methods in molecular biology (Clifton, N.J.)}, year = {2024}, doi = {10.1007/978-1-0716-3774-6_1}, pmid = {38427184}, url = {https://doi.org/10.1007/978-1-0716-3774-6_1} } @article{duan2024-38740448, author = {Duan, Sixuan and Cai, Tianyu and Liu, Fuyuan and Li, Yifan and Yuan, Hang and Yuan, Wenwen and Huang, Kaizhu and Hoettges, Kai and others}, title = {{Automatic offline-capable smartphone paper-based microfluidic device for efficient biomarker detection of Alzheimer's disease}}, journal = {Analytica chimica acta}, year = {2024}, doi = {10.1016/j.aca.2024.342575}, pmid = {38740448}, url = {https://doi.org/10.1016/j.aca.2024.342575} } @article{song2025-39997004, author = {Song, Jaeyoon and Cho, Eunseo and Lee, Huiseop and Lee, Suyoung and Kim, Sehyeon and Kim, Jinsik}, title = {{Development of Neurodegenerative Disease Diagnosis and Monitoring from Traditional to Digital Biomarkers}}, journal = {Biosensors}, year = {2025}, doi = {10.3390/bios15020102}, pmid = {39997004}, url = {https://doi.org/10.3390/bios15020102} } @article{li2023-37622844, author = {Li, Mifang and Zeng, Yu and Huang, Zhen and Zhang, Lingyan and Liu, Yibiao}, title = {{Vertical Graphene-Based Printed Electrochemical Biosensor for Simultaneous Detection of Four Alzheimer’s Disease Blood Biomarkers}}, journal = {Biosensors}, year = {2023}, doi = {10.3390/bios13080758}, pmid = {37622844}, url = {https://doi.org/10.3390/bios13080758} } @article{nath2023-37371324, author = {Nath, K. and Ferguson, I. and Puleio, A. and Wall, K. and Stark, J. and Clark, S. and Story, C. and Cohen, B. and others}, title = {{Brain Health Indicators Following Acute Neuro-Exergaming: Biomarker and Cognition in Mild Cognitive Impairment (MCI) after Pedal-n-Play (iPACES)}}, journal = {Brain sciences}, year = {2023}, doi = {10.3390/brainsci13060844}, pmid = {37371324}, url = {https://doi.org/10.3390/brainsci13060844} } @article{laske2007-16554070, author = {Laske, C. and Stransky, E. and Leyhe, T. and Eschweiler, G. W. and Maetzler, W. and Wittorf, A. and Soekadar, S. and Richartz, E. and others}, title = {{BDNF serum and CSF concentrations in Alzheimer's disease, normal pressure hydrocephalus and healthy controls}}, journal = {Journal of psychiatric research}, year = {2007}, doi = {10.1016/j.jpsychires.2006.01.014}, pmid = {16554070}, url = {https://doi.org/10.1016/j.jpsychires.2006.01.014} } @article{honey2025-41434517, author = {Honey, Madison I. J. and Hok-A-Hin, Yanaika Sylvana and Thijssen, Elisabeth H. and van der Weijden, Babette and Stoops, Erik and de Boer, Sterre C.M. and Duits, Flora Hillegonde and van der Ende, Emma Louise and others}, title = {{CSF Acetylated Tau‐174 as a novel diagnostic and prognostic biomarker in Frontotemporal Dementia and Alzheimer’s Disease}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz70861_108639}, pmid = {41434517}, url = {https://doi.org/10.1002/alz70861_108639} } @article{woyk2025-40290782, author = {Woyk, Katharina and Hansen, Niels and Wiltfang, Jens and Lange, Claudia and Bouter, Caroline}, title = {{The relationship of 18 F-FDG-PET to other common biomarkers of dementia in a clinical cohort with memory deficits}}, journal = {Journal of Alzheimer s Disease Reports}, year = {2025}, doi = {10.1177/25424823251314392}, pmid = {40290782}, url = {https://doi.org/10.1177/25424823251314392} } @article{booncharoen2025-41447122, author = {Booncharoen, Kittithatch and Hiransuthikul, Akarin and Likitjaroen, Yuttachai and Phanthumchinda, Kammant and Thanprasertsuk, Sekh and Thanapornsangsuth, Poosanu}, title = {{PET and Blood Biomarkers as Predictors of Short‐Term Progression in MCI and Mild Dementia: Prospective Insights from a Southeast Asian Middle‐Income Country}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz70856_100227}, pmid = {41447122}, url = {https://doi.org/10.1002/alz70856_100227} } @article{bruno2025-40986437, author = {Bruno, Davide and Plaska, Chelsea Reichert and Zinkunegi, Ainara Jauregi and Ashton, Nicholas J. and Zetterberg, Henrik and Blennow, Kaj and Pomara, Nunzio}, title = {{Associations of plasma p‐tau231 with serial position recall performance in free‐of‐dementia individuals}}, journal = {Journal of Neuropsychology}, year = {2025}, doi = {10.1111/jnp.70012}, pmid = {40986437}, url = {https://doi.org/10.1111/jnp.70012} } @article{wang2025-40025636, author = {Wang, Tianyi and Shang, Li and Mao, Chenhui and Sha, Longze and Dong, Liling and Liu, Caiyan and Lei, Dan and Li, Jie and others}, title = {{Alzheimer’s disease diagnosis among dementia patients via blood biomarker measurement based on the AT(N) system}}, journal = {Chinese Medical Journal}, year = {2025}, doi = {10.1097/cm9.0000000000003496}, pmid = {40025636}, url = {https://doi.org/10.1097/cm9.0000000000003496} } @article{koychev2019-30904851, author = {Koychev, I. and Lawson, J. and Chessell, T. and Mackay, C. and Gunn, R. and Sahakian, B. and Rowe, J. B. and Thomas, A. J. and others}, title = {{Deep and Frequent Phenotyping study protocol: an observational study in prodromal Alzheimer's disease}}, journal = {BMJ open}, year = {2019}, doi = {10.1136/bmjopen-2018-024498}, pmid = {30904851}, url = {https://doi.org/10.1136/bmjopen-2018-024498} } @article{mccaddon1998-9646150, author = {McCaddon, A. and Davies, G. and Hudson, P. and Tandy, S. and Cattell, H.}, title = {{Total serum homocysteine in senile dementia of Alzheimer type}}, journal = {International journal of geriatric psychiatry}, year = {1998}, doi = {10.1002/(sici)1099-1166(199804)13:4<235::aid-gps761>3.0.co;2-8}, pmid = {9646150}, url = {https://doi.org/10.1002/(sici)1099-1166(199804)13:4<235::aid-gps761>3.0.co;2-8} } @article{comi2010-20308780, author = {Comi, C. and Carecchio, M. and Chiocchetti, A. and Nicola, S. and Galimberti, D. and Fenoglio, C. and Cappellano, G. and Monaco, F. and others}, title = {{Osteopontin is increased in the cerebrospinal fluid of patients with Alzheimer's disease and its levels correlate with cognitive decline}}, journal = {Journal of Alzheimer's disease : JAD}, year = {2010}, doi = {10.3233/jad-2010-1309}, pmid = {20308780}, url = {https://doi.org/10.3233/jad-2010-1309} } @article{alosco2015-25628737, author = {Alosco, M. L. and Spitznagel, M. B. and Strain, G. and Devlin, M. and Cohen, R. and Crosby, R. D. and Mitchell, J. E. and Gunstad, J.}, title = {{Improved serum leptin and ghrelin following bariatric surgery predict better postoperative cognitive function}}, journal = {Journal of clinical neurology (Seoul, Korea)}, year = {2015}, doi = {10.3988/jcn.2015.11.1.48}, pmid = {25628737}, url = {https://doi.org/10.3988/jcn.2015.11.1.48} } @article{liu2022-35129691, author = {Liu, Y. and Huang, Z. and Xu, Q. and Zhang, L. and Liu, Q. and Xu, T.}, title = {{Portable electrochemical micro-workstation platform for simultaneous detection of multiple Alzheimer's disease biomarkers}}, journal = {Mikrochimica acta}, year = {2022}, doi = {10.1007/s00604-022-05199-4}, pmid = {35129691}, url = {https://doi.org/10.1007/s00604-022-05199-4} } @article{rutkowski2021-34892639, author = {Rutkowski, T. M. and Abe, M. S. and Otake-Matsuura, M.}, title = {{Neurotechnology and AI Approach for Early Dementia Onset Biomarker from EEG in Emotional Stimulus Evaluation Task}}, journal = {Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference}, year = {2021}, doi = {10.1109/embc46164.2021.9630736}, pmid = {34892639}, url = {https://doi.org/10.1109/embc46164.2021.9630736} } @article{mccaddon2001-11455131, author = {McCaddon, A. and Hudson, P. and Davies, G. and Hughes, A. and Williams, J. H. and Wilkinson, C.}, title = {{Homocysteine and cognitive decline in healthy elderly}}, journal = {Dementia and geriatric cognitive disorders}, year = {2001}, doi = {10.1159/000051275}, pmid = {11455131}, url = {https://doi.org/10.1159/000051275} } @article{chen2026-41823065, author = {Chen, Guan‐Wei and Liu, Yi‐Hung and Pan, Chih‐Chuan and Yen, Cheng-Chun and Yang, Jie-Kai and Chu, Che‐Sheng and Chen, Cheng‐Sheng}, title = {{Estimating cognitive function score from mild cognitive impairment to moderate dementia using a hybrid model combining plasma biomarkers with electroencephalogram signal}}, journal = {Journal of Alzheimer s Disease}, year = {2026}, doi = {10.1177/13872877261429861}, pmid = {41823065}, url = {https://doi.org/10.1177/13872877261429861} } @article{rai2020-32468532, author = {Rai, Laura and Boyle, Rory and Brosnan, Laura and Rice, Hannah and Farina, Francesca and Tarnanas, Ioannis and Whelan, Robert}, title = {{Digital Biomarkers Based Individualized Prognosis for People at Risk of Dementia: the AltoidaML Multi-site External Validation Study}}, journal = {Advances in experimental medicine and biology}, year = {2020}, doi = {10.1007/978-3-030-32622-7_14}, pmid = {32468532}, url = {https://doi.org/10.1007/978-3-030-32622-7_14} } @article{misra2026-42131707, author = {Misra, Arpita and Wang, Yi and Taheri, M. Reza and Chiang, Gloria Chia-Yi and Cho, Junghun}, title = {{Oxygen extraction fraction is differentially associated with pathological biomarkers in Alzheimer’s disease and non-Alzheimer’s dementias}}, journal = {Frontiers in Neuroscience}, year = {2026}, doi = {10.3389/fnins.2026.1754415}, pmid = {42131707}, url = {https://doi.org/10.3389/fnins.2026.1754415} } @article{lima2025-41443611, author = {Lima, Bruna Seixas and Rosa‐Neto, Pedro and Lahiri, Durjoy and Roncero, Carlos Tyler and Chertkow, Howard}, title = {{The relationship between neuroinflammation and clinical features of dementia: An investigation of GFAP levels in Alzheimer's disease and related disorders}}, journal = {Alzheimer s \& Dementia}, year = {2025}, doi = {10.1002/alz70856_098224}, pmid = {41443611}, url = {https://doi.org/10.1002/alz70856_098224} } @article{tudor2025-41009553, author = {Tudor, Lucija and Paska, Alja Videtič and Konjevod, Marcela and Balic, Nikola and Perković, Matea Nikolac and Uzun, Suzana and Vuić, Barbara and Milos, Tina and others}, title = {{BDNF Val66Met Genotype, DNA Methylation, mRNA, and Protein Levels as Potential Blood-Based Biomarkers for Dementia and Cognitive Decline}}, journal = {International Journal of Molecular Sciences}, year = {2025}, doi = {10.3390/ijms26188987}, pmid = {41009553}, url = {https://doi.org/10.3390/ijms26188987} } @article{brendler2026-bd891c91, author = {Brendler, A. and Fietz, J. and Bauer, A. and Pfahl, D. and Higgins, S. and Vidovic, E. and Brückl, T. and {BeCOME Working Group} and others}, title = {{Initial Technical and Clinical Validation of Mobile Pupillometry with Virtual Reality: A Digital Biomarker for Screening Cognitive Function and Impairment}}, journal = {medRxiv}, year = {2026}, doi = {10.64898/2026.07.15.26358187}, url = {https://doi.org/10.64898/2026.07.15.26358187} } @article{shi2026-540a9f49, author = {Shi, R. and Choity, L. T. and Brodman, S. T. and Zeng, X. and Farinas, M. F. and Nafash, M. N. and Gogola, A. and Lopresti, B. and others}, title = {{Association of age with clinical progression across plasma p-tau217 levels}}, journal = {medRxiv}, year = {2026}, doi = {10.64898/2026.08.08.26359816}, url = {https://doi.org/10.64898/2026.08.08.26359816} } @article{junior2026-a05254d1, author = {Junior, I. O. D. and Houston, K. J. and Rodriguez, D. S. and Brothers, T. and Germain, C. M.}, title = {{Electroretinography as a Noninvasive Biomarker of Alzheimer’s Disease and Related Dementias in Older Adults: A Systematic Scoping Review}}, journal = {Research Square}, year = {2026}, doi = {10.21203/rs.3.rs-10513623/v1}, url = {https://doi.org/10.21203/rs.3.rs-10513623/v1} }