{
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"highest": 88,
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"capped": 210,
"incomplete": 17784,
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"key": "journal",
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"avg_text": "7.4",
"max": 10,
"pct": 74.1,
"pct_text": "74.1",
"colour": "#3B1B57",
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"modal_count": 13751,
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{
"key": "venue",
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"blurb": "How much the journal's papers are cited over its whole life (its h-index in OpenAlex). It grades the many journals our tiers lump together. Old, large journals do best, so it is a track record, not a guarantee.",
"avg": 2.27,
"avg_text": "2.3",
"max": 4,
"pct": 56.9,
"pct_text": "56.9",
"colour": "#4D2F68",
"typical_points": 2,
"typical_count": 4515,
"typical_detail": "Alzheimer's & Dementia: journal h-index 228 (OpenAlex, 2026-10-29)",
"typical_example": "A randomized trial of two online platforms for dementia family caregivers: GamePlan4Care and Resources4Care",
"typical_example_idx": 107,
"modal_points": 2,
"modal_count": 4515,
"modal_detail": "Alzheimer's & Dementia: journal h-index 228 (OpenAlex, 2026-10-29)",
"modal_is_nearest": true,
"not_available": 3340,
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"left_out": 3340,
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{
"key": "design",
"label": "Study design",
"blurb": "How the study was built: a pooled review of many trials tells you more than one snapshot.",
"avg": 2.54,
"avg_text": "2.5",
"max": 12,
"pct": 21.2,
"pct_text": "21.2",
"colour": "#5F4379",
"typical_points": 3,
"typical_count": 20,
"typical_detail": "A computer model rather than new measurements",
"typical_example": "Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: an analysis for the Global Burden of Disease Study 2019",
"typical_example_idx": 51,
"modal_points": 0,
"modal_count": 12402,
"modal_detail": "No study design recorded — scores zero, not guessed",
"modal_is_nearest": false,
"not_available": 12402,
"scored_n": 17989,
"left_out": 0,
"not_stated": 12402
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{
"key": "evidence",
"label": "Strength of evidence",
"blurb": "How firm the finding is in our own summary of it, from preliminary up to high.",
"avg": 1.93,
"avg_text": "1.9",
"max": 5,
"pct": 38.5,
"pct_text": "38.5",
"colour": "#715789",
"typical_points": 2,
"typical_count": 64,
"typical_detail": "Rated “early” in our summary",
"typical_example": "FDA Approves LEQEMBI (lecanemab-irmb) Under the Accelerated Approval Pathway for the Treatment of Alzheimer's Disease",
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"modal_count": 11665,
"modal_detail": "Rated “low” in our summary",
"modal_is_nearest": false,
"not_available": 257,
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"left_out": 257,
"not_stated": 0
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{
"key": "validation",
"label": "Peer-review validation",
"blurb": "Whether other scientists checked it before publication.",
"avg": 9.92,
"avg_text": "9.9",
"max": 10,
"pct": 99.2,
"pct_text": "99.2",
"colour": "#836B9A",
"typical_points": 10,
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"typical_detail": "Peer-reviewed. Published as an article in a named peer-reviewed journal",
"typical_example": "Blood Biomarkers to Detect Alzheimer Disease in Primary Care and Secondary Care",
"typical_example_idx": 1,
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"modal_detail": "Peer-reviewed. Published as an article in a named peer-reviewed journal",
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{
"key": "recency",
"label": "How recent",
"blurb": "How close it is to the newest study we carry.",
"avg": 2.53,
"avg_text": "2.5",
"max": 5,
"pct": 50.7,
"pct_text": "50.7",
"colour": "#957EAB",
"typical_points": 3,
"typical_count": 2035,
"typical_detail": "2020 — within 6 years of the newest study here",
"typical_example": "APOE2 is associated with longevity independent of Alzheimer's disease",
"typical_example_idx": 36,
"modal_points": 1,
"modal_count": 7845,
"modal_detail": "2015 — within 20 years of the newest study here",
"modal_is_nearest": false,
"not_available": 4,
"scored_n": 17985,
"left_out": 4,
"not_stated": 0
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{
"key": "size",
"label": "Sample size",
"blurb": "How many people were in it, in bands: a blank count scores nothing.",
"avg": 0.8,
"avg_text": "0.8",
"max": 4,
"pct": 20.0,
"pct_text": "20",
"colour": "#A792BC",
"typical_points": 1,
"typical_count": 2113,
"typical_detail": "20 participants",
"typical_example": "Quantification of plasma phosphorylated tau to use as a biomarker for brain Alzheimer pathology: pilot case-control studies including patients with Alzheimer's disease and down syndrome",
"typical_example_idx": 441,
"modal_points": 0,
"modal_count": 11120,
"modal_detail": "Participant count not stated — scores zero",
"modal_is_nearest": false,
"not_available": 11120,
"scored_n": 17989,
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{
"key": "effect",
"label": "Effect reported",
"blurb": "Whether it reports how big the effect was, and with an interval or test rather than a bare number.",
"avg": 0.47,
"avg_text": "0.5",
"max": 3,
"pct": 15.7,
"pct_text": "15.7",
"colour": "#B9A6CC",
"typical_points": 0,
"typical_count": 14301,
"typical_detail": "No effect size reported — scores zero",
"typical_example": "Revised Criteria for Diagnosis and Staging of Alzheimer's Disease: Alzheimer's Association Workgroup",
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"modal_count": 14301,
"modal_detail": "No effect size reported — scores zero",
"modal_is_nearest": true,
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{
"key": "humans",
"label": "Studied in people",
"blurb": "Whether the record shows it was done in people, not in mice or a dish.",
"avg": 1.23,
"avg_text": "1.2",
"max": 3,
"pct": 41.1,
"pct_text": "41.1",
"colour": "#CBBADD",
"typical_points": 0,
"typical_count": 10589,
"typical_detail": "Not stated whether this was studied in people — scores zero",
"typical_example": "Revised Criteria for Diagnosis and Staging of Alzheimer's Disease: Alzheimer's Association Workgroup",
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"modal_count": 10589,
"modal_detail": "Not stated whether this was studied in people — scores zero",
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"not_available": 9790,
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"left_out": 0,
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{
"key": "random",
"label": "Randomised / blinded",
"blurb": "Whether the study itself says it was randomised, and whether it was blinded.",
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"max": 2,
"pct": 4.6,
"pct_text": "4.6",
"colour": "#DDCEEE",
"typical_points": 0,
"typical_count": 16739,
"typical_detail": "No randomisation or blinding stated — scores zero",
"typical_example": "Blood Biomarkers to Detect Alzheimer Disease in Primary Care and Secondary Care",
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"modal_detail": "No randomisation or blinding stated — scores zero",
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{
"key": "cited",
"label": "Times cited",
"blurb": "How many times other papers have cited it, as counted by OpenAlex, in bands.",
"avg": 3.81,
"avg_text": "3.8",
"max": 7,
"pct": 54.4,
"pct_text": "54.4",
"colour": "#0F4C4C",
"typical_points": 4,
"typical_count": 1872,
"typical_detail": "Cited 66 times (OpenAlex, 2026-10-10)",
"typical_example": "Long-term physical exercise facilitates putative glymphatic and meningeal lymphatic vessel flow in humans",
"typical_example_idx": 352,
"modal_points": 5,
"modal_count": 3939,
"modal_detail": "Cited 116 times (OpenAlex, 2026-10-10)",
"modal_is_nearest": false,
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{
"key": "velocity",
"label": "Citations per year",
"blurb": "Citations per year since it came out, so a new paper is not judged against a thirty-year head start.",
"avg": 2.49,
"avg_text": "2.5",
"max": 5,
"pct": 49.9,
"pct_text": "49.9",
"colour": "#1E6B66",
"typical_points": 2,
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"typical_detail": "3.0 citations a year over 2 years since 2025",
"typical_example": "Two-step detection of Lewy body pathology via smell-function testing and CSF α-synuclein seed amplification",
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"modal_count": 4082,
"modal_detail": "8.0 citations a year over 2 years since 2025",
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"not_available": 2993,
"scored_n": 14996,
"left_out": 2993,
"not_stated": 0
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{
"key": "fwci",
"label": "Impact for its field and year",
"blurb": "OpenAlex's field-weighted citation impact: its citations against the average for papers of the same field and year.",
"avg": 3.17,
"avg_text": "3.2",
"max": 6,
"pct": 52.8,
"pct_text": "52.8",
"colour": "#348A80",
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"typical_example": "Mapping dementia risk factors and their interactions in Denmark: a nationwide cohort study",
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{
"key": "library",
"label": "Cited by studies here",
"blurb": "How many other studies in this library cite it, counted from the reference lists of the studies we hold.",
"avg": 1.43,
"avg_text": "1.4",
"max": 6,
"pct": 23.9,
"pct_text": "23.9",
"colour": "#55A89B",
"typical_points": 1,
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"typical_detail": "Cited by 1 other study in this library",
"typical_example": "Music-based therapeutic interventions for people with dementia (Cochrane review update)",
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"modal_count": 5533,
"modal_detail": "No other study in this library cites it",
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{
"key": "recent",
"label": "Still being cited",
"blurb": "How often it was cited in the last three calendar years: is the field still using it?",
"avg": 1.66,
"avg_text": "1.7",
"max": 4,
"pct": 41.5,
"pct_text": "41.5",
"colour": "#82C4B8",
"typical_points": 2,
"typical_count": 4126,
"typical_detail": "Cited 16 times in 2024–2026 (2026 still in progress; OpenAlex)",
"typical_example": "Escitalopram for agitation in Alzheimer's dementia: a randomized controlled phase 3 trial",
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"modal_count": 4126,
"modal_detail": "Cited 16 times in 2024–2026 (2026 still in progress; OpenAlex)",
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{
"key": "author",
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"avg_text": "2.7",
"max": 4,
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"pct_text": "66.4",
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{
"key": "institution",
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"blurb": "The h-index of the strongest institution on the paper, from OpenAlex. A track record, not a guarantee.",
"avg": 1.43,
"avg_text": "1.4",
"max": 3,
"pct": 47.5,
"pct_text": "47.5",
"colour": "#A86A22",
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"typical_detail": "The strongest institution on the paper has an h-index of 1,477 (OpenAlex)",
"typical_example": "Diet Quality and Dementia Risk in Older Adults With Alzheimer Pathology",
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"scored_n": 14597,
"left_out": 3392,
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{
"key": "collab",
"label": "Multi-centre collaboration",
"blurb": "How many institutions took part. Work repeated across several centres is harder to get by chance.",
"avg": 1.34,
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"pct_text": "44.7",
"colour": "#D09447",
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"key": "indexed",
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"pct_text": "96.4",
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"modal_detail": "Indexed in PubMed (PMID 31413141)",
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{
"key": "open",
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"avg_text": "0.8",
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"pct_text": "41.1",
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"typical_detail": "Behind a paywall — scores zero",
"typical_example": "Two Randomized Phase 3 Studies of Aducanumab in Early Alzheimer's Disease",
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"count": 630,
"min": 16,
"max": 69,
"q1": 41.0,
"median": 45.0,
"q3": 48.0,
"small": false,
"peer_reviewed": 623
},
{
"key": "clinical_safety",
"label": "Clinical safety",
"count": 569,
"min": 24,
"max": 86,
"q1": 39.0,
"median": 45,
"q3": 57.0,
"small": false,
"peer_reviewed": 569
},
{
"key": "end_of_life",
"label": "End-of-life care",
"count": 698,
"min": 15,
"max": 86,
"q1": 38.0,
"median": 44.0,
"q3": 53.0,
"small": false,
"peer_reviewed": 696
},
{
"key": "imaging_hippocampus",
"label": "Hippocampus size on brain scans",
"count": 492,
"min": 36,
"max": 84,
"q1": 36.0,
"median": 43.0,
"q3": 52.0,
"small": false,
"peer_reviewed": 492
},
{
"key": "mechanisms",
"label": "Disease mechanisms",
"count": 666,
"min": 25,
"max": 74,
"q1": 36.0,
"median": 40.0,
"q3": 45.0,
"small": false,
"peer_reviewed": 666
},
{
"key": "down_syndrome",
"label": "Down syndrome and Alzheimer's",
"count": 538,
"min": 16,
"max": 68,
"q1": 35.0,
"median": 39.0,
"q3": 44.0,
"small": false,
"peer_reviewed": 526
},
{
"key": "health_systems",
"label": "Health systems and care delivery",
"count": 477,
"min": 9,
"max": 69,
"q1": 33.0,
"median": 39,
"q3": 47.0,
"small": false,
"peer_reviewed": 467
},
{
"key": "drug_development",
"label": "Drug development",
"count": 94,
"min": 16,
"max": 69,
"q1": 34.0,
"median": 39.0,
"q3": 47.8,
"small": false,
"peer_reviewed": 90
}
],
"designs": [
{
"key": "basic-science",
"label": "Laboratory science",
"count": 46,
"small": false,
"counts": {
"systematic-review": 0,
"meta-analysis": 0,
"rct": 1,
"trial": 1,
"cohort": 15,
"case-control": 4,
"cross-sectional": 1,
"other": 24
},
"observational": 20
},
{
"key": "health-economics",
"label": "Costs and economics",
"count": 40,
"small": false,
"counts": {
"systematic-review": 2,
"meta-analysis": 0,
"rct": 6,
"trial": 0,
"cohort": 10,
"case-control": 0,
"cross-sectional": 3,
"other": 19
},
"observational": 13
},
{
"key": "biomarkers",
"label": "Biomarkers",
"count": 796,
"small": false,
"counts": {
"systematic-review": 0,
"meta-analysis": 9,
"rct": 0,
"trial": 1,
"cohort": 24,
"case-control": 0,
"cross-sectional": 108,
"other": 654
},
"observational": 132
},
{
"key": "disparities",
"label": "Disparities",
"count": 689,
"small": false,
"counts": {
"systematic-review": 0,
"meta-analysis": 16,
"rct": 0,
"trial": 0,
"cohort": 0,
"case-control": 0,
"cross-sectional": 64,
"other": 609
},
"observational": 64
},
{
"key": "vascular",
"label": "Vascular contributions",
"count": 379,
"small": false,
"counts": {
"systematic-review": 0,
"meta-analysis": 12,
"rct": 0,
"trial": 0,
"cohort": 0,
"case-control": 0,
"cross-sectional": 34,
"other": 333
},
"observational": 34
},
{
"key": "cohorts",
"label": "Long-term cohort studies",
"count": 512,
"small": false,
"counts": {
"systematic-review": 0,
"meta-analysis": 13,
"rct": 0,
"trial": 0,
"cohort": 0,
"case-control": 0,
"cross-sectional": 45,
"other": 454
},
"observational": 45
},
{
"key": "genetics",
"label": "Genetics",
"count": 802,
"small": false,
"counts": {
"systematic-review": 0,
"meta-analysis": 27,
"rct": 1,
"trial": 0,
"cohort": 14,
"case-control": 11,
"cross-sectional": 44,
"other": 705
},
"observational": 69
},
{
"key": "caregiving",
"label": "Caregiving",
"count": 677,
"small": false,
"counts": {
"systematic-review": 2,
"meta-analysis": 40,
"rct": 13,
"trial": 0,
"cohort": 2,
"case-control": 0,
"cross-sectional": 55,
"other": 565
},
"observational": 57
},
{
"key": "end_of_life",
"label": "End-of-life care",
"count": 698,
"small": false,
"counts": {
"systematic-review": 0,
"meta-analysis": 6,
"rct": 0,
"trial": 0,
"cohort": 0,
"case-control": 0,
"cross-sectional": 58,
"other": 634
},
"observational": 58
},
{
"key": "epidemiology",
"label": "How common it is",
"count": 493,
"small": false,
"counts": {
"systematic-review": 0,
"meta-analysis": 20,
"rct": 0,
"trial": 0,
"cohort": 12,
"case-control": 0,
"cross-sectional": 28,
"other": 433
},
"observational": 40
},
{
"key": "biomarkers_tau",
"label": "Tau biomarkers",
"count": 447,
"small": false,
"counts": {
"systematic-review": 0,
"meta-analysis": 5,
"rct": 0,
"trial": 0,
"cohort": 0,
"case-control": 0,
"cross-sectional": 36,
"other": 406
},
"observational": 36
},
{
"key": "assessment",
"label": "Cognitive tests and assessment",
"count": 560,
"small": false,
"counts": {
"systematic-review": 0,
"meta-analysis": 9,
"rct": 0,
"trial": 0,
"cohort": 0,
"case-control": 0,
"cross-sectional": 45,
"other": 506
},
"observational": 45
},
{
"key": "imaging",
"label": "Brain scans and imaging",
"count": 624,
"small": false,
"counts": {
"systematic-review": 0,
"meta-analysis": 3,
"rct": 0,
"trial": 0,
"cohort": 0,
"case-control": 0,
"cross-sectional": 50,
"other": 571
},
"observational": 50
},
{
"key": "risk_factors",
"label": "Risk factors",
"count": 979,
"small": false,
"counts": {
"systematic-review": 0,
"meta-analysis": 36,
"rct": 0,
"trial": 0,
"cohort": 0,
"case-control": 0,
"cross-sectional": 76,
"other": 867
},
"observational": 76
},
{
"key": "prevention",
"label": "Prevention and risk",
"count": 872,
"small": false,
"counts": {
"systematic-review": 1,
"meta-analysis": 74,
"rct": 12,
"trial": 1,
"cohort": 45,
"case-control": 0,
"cross-sectional": 21,
"other": 718
},
"observational": 66
},
{
"key": "imaging_hippocampus",
"label": "Hippocampus size on brain scans",
"count": 492,
"small": false,
"counts": {
"systematic-review": 0,
"meta-analysis": 19,
"rct": 0,
"trial": 0,
"cohort": 0,
"case-control": 0,
"cross-sectional": 37,
"other": 436
},
"observational": 37
},
{
"key": "diagnosis",
"label": "Getting a diagnosis",
"count": 781,
"small": false,
"counts": {
"systematic-review": 4,
"meta-analysis": 17,
"rct": 2,
"trial": 0,
"cohort": 5,
"case-control": 0,
"cross-sectional": 47,
"other": 706
},
"observational": 52
},
{
"key": "health_systems",
"label": "Health systems and care delivery",
"count": 477,
"small": false,
"counts": {
"systematic-review": 0,
"meta-analysis": 5,
"rct": 0,
"trial": 0,
"cohort": 0,
"case-control": 0,
"cross-sectional": 31,
"other": 441
},
"observational": 31
},
{
"key": "mci",
"label": "Mild cognitive impairment",
"count": 667,
"small": false,
"counts": {
"systematic-review": 0,
"meta-analysis": 12,
"rct": 0,
"trial": 0,
"cohort": 0,
"case-control": 0,
"cross-sectional": 33,
"other": 622
},
"observational": 33
},
{
"key": "prevention_trials",
"label": "Prevention trials",
"count": 662,
"small": false,
"counts": {
"systematic-review": 0,
"meta-analysis": 35,
"rct": 0,
"trial": 0,
"cohort": 0,
"case-control": 0,
"cross-sectional": 25,
"other": 602
},
"observational": 25
},
{
"key": "digital",
"label": "Digital health tools",
"count": 739,
"small": false,
"counts": {
"systematic-review": 0,
"meta-analysis": 11,
"rct": 0,
"trial": 0,
"cohort": 0,
"case-control": 0,
"cross-sectional": 26,
"other": 702
},
"observational": 26
},
{
"key": "down_syndrome",
"label": "Down syndrome and Alzheimer's",
"count": 538,
"small": false,
"counts": {
"systematic-review": 0,
"meta-analysis": 1,
"rct": 0,
"trial": 0,
"cohort": 0,
"case-control": 0,
"cross-sectional": 18,
"other": 519
},
"observational": 18
},
{
"key": "drug_development",
"label": "Drug development",
"count": 94,
"small": false,
"counts": {
"systematic-review": 0,
"meta-analysis": 4,
"rct": 0,
"trial": 0,
"cohort": 0,
"case-control": 0,
"cross-sectional": 3,
"other": 87
},
"observational": 3
},
{
"key": "neuropathology",
"label": "Brain tissue and pathology",
"count": 447,
"small": false,
"counts": {
"systematic-review": 0,
"meta-analysis": 7,
"rct": 0,
"trial": 0,
"cohort": 0,
"case-control": 0,
"cross-sectional": 12,
"other": 428
},
"observational": 12
},
{
"key": "clinical_safety",
"label": "Clinical safety",
"count": 569,
"small": false,
"counts": {
"systematic-review": 0,
"meta-analysis": 24,
"rct": 0,
"trial": 0,
"cohort": 0,
"case-control": 0,
"cross-sectional": 14,
"other": 531
},
"observational": 14
},
{
"key": "treatments",
"label": "Treatments",
"count": 809,
"small": false,
"counts": {
"systematic-review": 2,
"meta-analysis": 18,
"rct": 3,
"trial": 4,
"cohort": 6,
"case-control": 1,
"cross-sectional": 9,
"other": 766
},
"observational": 16
},
{
"key": "mechanisms",
"label": "Disease mechanisms",
"count": 666,
"small": false,
"counts": {
"systematic-review": 0,
"meta-analysis": 6,
"rct": 0,
"trial": 0,
"cohort": 0,
"case-control": 0,
"cross-sectional": 10,
"other": 650
},
"observational": 10
},
{
"key": "lewy_body",
"label": "Lewy body dementia",
"count": 543,
"small": false,
"counts": {
"systematic-review": 0,
"meta-analysis": 0,
"rct": 0,
"trial": 0,
"cohort": 0,
"case-control": 0,
"cross-sectional": 8,
"other": 535
},
"observational": 8
},
{
"key": "genetics_trem2",
"label": "TREM2 and immune genetics",
"count": 580,
"small": false,
"counts": {
"systematic-review": 0,
"meta-analysis": 23,
"rct": 0,
"trial": 0,
"cohort": 0,
"case-control": 0,
"cross-sectional": 8,
"other": 549
},
"observational": 8
},
{
"key": "genetics_genes",
"label": "Risk genes beyond APOE",
"count": 630,
"small": false,
"counts": {
"systematic-review": 0,
"meta-analysis": 7,
"rct": 0,
"trial": 0,
"cohort": 0,
"case-control": 0,
"cross-sectional": 4,
"other": 619
},
"observational": 4
},
{
"key": "inflammation",
"label": "Inflammation and the immune system",
"count": 659,
"small": false,
"counts": {
"systematic-review": 0,
"meta-analysis": 12,
"rct": 0,
"trial": 0,
"cohort": 0,
"case-control": 0,
"cross-sectional": 3,
"other": 644
},
"observational": 3
},
{
"key": "clinical-trial",
"label": "Clinical trials",
"count": 22,
"small": false,
"counts": {
"systematic-review": 0,
"meta-analysis": 0,
"rct": 2,
"trial": 17,
"cohort": 0,
"case-control": 0,
"cross-sectional": 0,
"other": 3
},
"observational": 0
}
],
"figures": [
{
"id": "fig-dist",
"title": "How the scores are spread",
"subtitle": "Every study in the library, in 5-point bins. Median 49, range 9–88.",
"svg": "",
"caption": "n = 17989 studies — the whole library. The scores are computed from the study records we hold, and the counts are read from the same data. The line at 16 is the peer-review cap: 232 entries are not peer-reviewed research articles, and the rubric stops them there by construction, so none can outrank a peer-reviewed paper. The lowest-scoring peer-reviewed article in the library scores 21.",
"table": {
"columns": [
"Score range",
"Studies"
],
"rows": [
[
"0–4",
0
],
[
"5–9",
1
],
[
"10–14",
9
],
[
"15–19",
222
],
[
"20–24",
30
],
[
"25–29",
320
],
[
"30–34",
643
],
[
"35–39",
2044
],
[
"40–44",
2987
],
[
"45–49",
3170
],
[
"50–54",
2761
],
[
"55–59",
2108
],
[
"60–64",
1554
],
[
"65–69",
1097
],
[
"70–74",
627
],
[
"75–79",
291
],
[
"80–84",
110
],
[
"85–89",
15
],
[
"90–94",
0
],
[
"95–99",
0
]
]
}
},
{
"id": "fig-comp",
"title": "Where the points come from",
"subtitle": "The library is strongest on peer-review validation (99.2% of the points on offer) and weakest on randomised / blinded (4.6%).",
"svg": "",
"caption": "n = 17989 studies. Each average is the mean of that component's points across the studies it was scored on. Where we have no data for a study, that component is left out of its score, so it is left out of the average too; the table says how many. The wording under each row is the record's own explanation, quoted from a study that sits closest to the average, with the names of authors and institutions taken out.",
"components": [
{
"key": "journal",
"label": "Journal tier",
"blurb": "Which journal published it, placed in ordered tiers — never a numeric impact factor.",
"avg": 7.41,
"avg_text": "7.4",
"max": 10,
"pct": 74.1,
"pct_text": "74.1",
"colour": "#3B1B57",
"typical_points": 7,
"typical_count": 13751,
"typical_detail": "Tier 3 — peer-reviewed journal (Alzheimer's & Dementia)",
"typical_example": "Eating and swallowing care disparities in persons with dementia: A conceptual framework",
"typical_example_idx": 10109,
"modal_points": 7,
"modal_count": 13751,
"modal_detail": "Tier 3 — peer-reviewed journal (Alzheimer's & Dementia)",
"modal_is_nearest": true,
"not_available": 2,
"scored_n": 17989,
"left_out": 0,
"not_stated": 2
},
{
"key": "venue",
"label": "Journal's citation record",
"blurb": "How much the journal's papers are cited over its whole life (its h-index in OpenAlex). It grades the many journals our tiers lump together. Old, large journals do best, so it is a track record, not a guarantee.",
"avg": 2.27,
"avg_text": "2.3",
"max": 4,
"pct": 56.9,
"pct_text": "56.9",
"colour": "#4D2F68",
"typical_points": 2,
"typical_count": 4515,
"typical_detail": "Alzheimer's & Dementia: journal h-index 228 (OpenAlex, 2026-10-29)",
"typical_example": "A randomized trial of two online platforms for dementia family caregivers: GamePlan4Care and Resources4Care",
"typical_example_idx": 107,
"modal_points": 2,
"modal_count": 4515,
"modal_detail": "Alzheimer's & Dementia: journal h-index 228 (OpenAlex, 2026-10-29)",
"modal_is_nearest": true,
"not_available": 3340,
"scored_n": 14649,
"left_out": 3340,
"not_stated": 0
},
{
"key": "design",
"label": "Study design",
"blurb": "How the study was built: a pooled review of many trials tells you more than one snapshot.",
"avg": 2.54,
"avg_text": "2.5",
"max": 12,
"pct": 21.2,
"pct_text": "21.2",
"colour": "#5F4379",
"typical_points": 3,
"typical_count": 20,
"typical_detail": "A computer model rather than new measurements",
"typical_example": "Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: an analysis for the Global Burden of Disease Study 2019",
"typical_example_idx": 51,
"modal_points": 0,
"modal_count": 12402,
"modal_detail": "No study design recorded — scores zero, not guessed",
"modal_is_nearest": false,
"not_available": 12402,
"scored_n": 17989,
"left_out": 0,
"not_stated": 12402
},
{
"key": "evidence",
"label": "Strength of evidence",
"blurb": "How firm the finding is in our own summary of it, from preliminary up to high.",
"avg": 1.93,
"avg_text": "1.9",
"max": 5,
"pct": 38.5,
"pct_text": "38.5",
"colour": "#715789",
"typical_points": 2,
"typical_count": 64,
"typical_detail": "Rated “early” in our summary",
"typical_example": "FDA Approves LEQEMBI (lecanemab-irmb) Under the Accelerated Approval Pathway for the Treatment of Alzheimer's Disease",
"typical_example_idx": 14,
"modal_points": 1,
"modal_count": 11665,
"modal_detail": "Rated “low” in our summary",
"modal_is_nearest": false,
"not_available": 257,
"scored_n": 17732,
"left_out": 257,
"not_stated": 0
},
{
"key": "validation",
"label": "Peer-review validation",
"blurb": "Whether other scientists checked it before publication.",
"avg": 9.92,
"avg_text": "9.9",
"max": 10,
"pct": 99.2,
"pct_text": "99.2",
"colour": "#836B9A",
"typical_points": 10,
"typical_count": 17757,
"typical_detail": "Peer-reviewed. Published as an article in a named peer-reviewed journal",
"typical_example": "Blood Biomarkers to Detect Alzheimer Disease in Primary Care and Secondary Care",
"typical_example_idx": 1,
"modal_points": 10,
"modal_count": 17757,
"modal_detail": "Peer-reviewed. Published as an article in a named peer-reviewed journal",
"modal_is_nearest": true,
"not_available": 0,
"scored_n": 17989,
"left_out": 0,
"not_stated": 0
},
{
"key": "recency",
"label": "How recent",
"blurb": "How close it is to the newest study we carry.",
"avg": 2.53,
"avg_text": "2.5",
"max": 5,
"pct": 50.7,
"pct_text": "50.7",
"colour": "#957EAB",
"typical_points": 3,
"typical_count": 2035,
"typical_detail": "2020 — within 6 years of the newest study here",
"typical_example": "APOE2 is associated with longevity independent of Alzheimer's disease",
"typical_example_idx": 36,
"modal_points": 1,
"modal_count": 7845,
"modal_detail": "2015 — within 20 years of the newest study here",
"modal_is_nearest": false,
"not_available": 4,
"scored_n": 17985,
"left_out": 4,
"not_stated": 0
},
{
"key": "size",
"label": "Sample size",
"blurb": "How many people were in it, in bands: a blank count scores nothing.",
"avg": 0.8,
"avg_text": "0.8",
"max": 4,
"pct": 20.0,
"pct_text": "20",
"colour": "#A792BC",
"typical_points": 1,
"typical_count": 2113,
"typical_detail": "20 participants",
"typical_example": "Quantification of plasma phosphorylated tau to use as a biomarker for brain Alzheimer pathology: pilot case-control studies including patients with Alzheimer's disease and down syndrome",
"typical_example_idx": 441,
"modal_points": 0,
"modal_count": 11120,
"modal_detail": "Participant count not stated — scores zero",
"modal_is_nearest": false,
"not_available": 11120,
"scored_n": 17989,
"left_out": 0,
"not_stated": 11120
},
{
"key": "effect",
"label": "Effect reported",
"blurb": "Whether it reports how big the effect was, and with an interval or test rather than a bare number.",
"avg": 0.47,
"avg_text": "0.5",
"max": 3,
"pct": 15.7,
"pct_text": "15.7",
"colour": "#B9A6CC",
"typical_points": 0,
"typical_count": 14301,
"typical_detail": "No effect size reported — scores zero",
"typical_example": "Revised Criteria for Diagnosis and Staging of Alzheimer's Disease: Alzheimer's Association Workgroup",
"typical_example_idx": 2,
"modal_points": 0,
"modal_count": 14301,
"modal_detail": "No effect size reported — scores zero",
"modal_is_nearest": true,
"not_available": 14299,
"scored_n": 17989,
"left_out": 0,
"not_stated": 14299
},
{
"key": "humans",
"label": "Studied in people",
"blurb": "Whether the record shows it was done in people, not in mice or a dish.",
"avg": 1.23,
"avg_text": "1.2",
"max": 3,
"pct": 41.1,
"pct_text": "41.1",
"colour": "#CBBADD",
"typical_points": 0,
"typical_count": 10589,
"typical_detail": "Not stated whether this was studied in people — scores zero",
"typical_example": "Revised Criteria for Diagnosis and Staging of Alzheimer's Disease: Alzheimer's Association Workgroup",
"typical_example_idx": 2,
"modal_points": 0,
"modal_count": 10589,
"modal_detail": "Not stated whether this was studied in people — scores zero",
"modal_is_nearest": true,
"not_available": 9790,
"scored_n": 17989,
"left_out": 0,
"not_stated": 9790
},
{
"key": "random",
"label": "Randomised / blinded",
"blurb": "Whether the study itself says it was randomised, and whether it was blinded.",
"avg": 0.09,
"avg_text": "0.1",
"max": 2,
"pct": 4.6,
"pct_text": "4.6",
"colour": "#DDCEEE",
"typical_points": 0,
"typical_count": 16739,
"typical_detail": "No randomisation or blinding stated — scores zero",
"typical_example": "Blood Biomarkers to Detect Alzheimer Disease in Primary Care and Secondary Care",
"typical_example_idx": 1,
"modal_points": 0,
"modal_count": 16739,
"modal_detail": "No randomisation or blinding stated — scores zero",
"modal_is_nearest": true,
"not_available": 15620,
"scored_n": 17989,
"left_out": 0,
"not_stated": 15620
},
{
"key": "cited",
"label": "Times cited",
"blurb": "How many times other papers have cited it, as counted by OpenAlex, in bands.",
"avg": 3.81,
"avg_text": "3.8",
"max": 7,
"pct": 54.4,
"pct_text": "54.4",
"colour": "#0F4C4C",
"typical_points": 4,
"typical_count": 1872,
"typical_detail": "Cited 66 times (OpenAlex, 2026-10-10)",
"typical_example": "Long-term physical exercise facilitates putative glymphatic and meningeal lymphatic vessel flow in humans",
"typical_example_idx": 352,
"modal_points": 5,
"modal_count": 3939,
"modal_detail": "Cited 116 times (OpenAlex, 2026-10-10)",
"modal_is_nearest": false,
"not_available": 2989,
"scored_n": 15000,
"left_out": 2989,
"not_stated": 0
},
{
"key": "velocity",
"label": "Citations per year",
"blurb": "Citations per year since it came out, so a new paper is not judged against a thirty-year head start.",
"avg": 2.49,
"avg_text": "2.5",
"max": 5,
"pct": 49.9,
"pct_text": "49.9",
"colour": "#1E6B66",
"typical_points": 2,
"typical_count": 2944,
"typical_detail": "3.0 citations a year over 2 years since 2025",
"typical_example": "Two-step detection of Lewy body pathology via smell-function testing and CSF α-synuclein seed amplification",
"typical_example_idx": 171,
"modal_points": 3,
"modal_count": 4082,
"modal_detail": "8.0 citations a year over 2 years since 2025",
"modal_is_nearest": false,
"not_available": 2993,
"scored_n": 14996,
"left_out": 2993,
"not_stated": 0
},
{
"key": "fwci",
"label": "Impact for its field and year",
"blurb": "OpenAlex's field-weighted citation impact: its citations against the average for papers of the same field and year.",
"avg": 3.17,
"avg_text": "3.2",
"max": 6,
"pct": 52.8,
"pct_text": "52.8",
"colour": "#348A80",
"typical_points": 3,
"typical_count": 4459,
"typical_detail": "Cited 4.7× the average for papers of its field and year (OpenAlex FWCI)",
"typical_example": "Mapping dementia risk factors and their interactions in Denmark: a nationwide cohort study",
"typical_example_idx": 153,
"modal_points": 3,
"modal_count": 4459,
"modal_detail": "Cited 4.7× the average for papers of its field and year (OpenAlex FWCI)",
"modal_is_nearest": true,
"not_available": 3245,
"scored_n": 14744,
"left_out": 3245,
"not_stated": 0
},
{
"key": "library",
"label": "Cited by studies here",
"blurb": "How many other studies in this library cite it, counted from the reference lists of the studies we hold.",
"avg": 1.43,
"avg_text": "1.4",
"max": 6,
"pct": 23.9,
"pct_text": "23.9",
"colour": "#55A89B",
"typical_points": 1,
"typical_count": 2581,
"typical_detail": "Cited by 1 other study in this library",
"typical_example": "Music-based therapeutic interventions for people with dementia (Cochrane review update)",
"typical_example_idx": 112,
"modal_points": 0,
"modal_count": 5533,
"modal_detail": "No other study in this library cites it",
"modal_is_nearest": false,
"not_available": 2740,
"scored_n": 15249,
"left_out": 2740,
"not_stated": 0
},
{
"key": "recent",
"label": "Still being cited",
"blurb": "How often it was cited in the last three calendar years: is the field still using it?",
"avg": 1.66,
"avg_text": "1.7",
"max": 4,
"pct": 41.5,
"pct_text": "41.5",
"colour": "#82C4B8",
"typical_points": 2,
"typical_count": 4126,
"typical_detail": "Cited 16 times in 2024–2026 (2026 still in progress; OpenAlex)",
"typical_example": "Escitalopram for agitation in Alzheimer's dementia: a randomized controlled phase 3 trial",
"typical_example_idx": 115,
"modal_points": 2,
"modal_count": 4126,
"modal_detail": "Cited 16 times in 2024–2026 (2026 still in progress; OpenAlex)",
"modal_is_nearest": true,
"not_available": 2989,
"scored_n": 15000,
"left_out": 2989,
"not_stated": 0
},
{
"key": "author",
"label": "Senior author's track record",
"blurb": "The last-listed (usually senior) author's career h-index in OpenAlex. A track record, not a guarantee.",
"avg": 2.65,
"avg_text": "2.7",
"max": 4,
"pct": 66.4,
"pct_text": "66.4",
"colour": "#7A4A12",
"typical_points": 3,
"typical_count": 4477,
"typical_detail": "The last-listed author has a career h-index of 94 (OpenAlex)",
"typical_example": "Glymphatic system dysfunction predicts amyloid deposition, neurodegeneration, and clinical progression in Alzheimer's disease",
"typical_example_idx": 353,
"modal_points": 3,
"modal_count": 4477,
"modal_detail": "The last-listed author has a career h-index of 94 (OpenAlex)",
"modal_is_nearest": true,
"not_available": 4530,
"scored_n": 13459,
"left_out": 4530,
"not_stated": 0
},
{
"key": "institution",
"label": "Institution's track record",
"blurb": "The h-index of the strongest institution on the paper, from OpenAlex. A track record, not a guarantee.",
"avg": 1.43,
"avg_text": "1.4",
"max": 3,
"pct": 47.5,
"pct_text": "47.5",
"colour": "#A86A22",
"typical_points": 1,
"typical_count": 5227,
"typical_detail": "The strongest institution on the paper has an h-index of 1,477 (OpenAlex)",
"typical_example": "Diet Quality and Dementia Risk in Older Adults With Alzheimer Pathology",
"typical_example_idx": 148,
"modal_points": 1,
"modal_count": 5227,
"modal_detail": "The strongest institution on the paper has an h-index of 1,477 (OpenAlex)",
"modal_is_nearest": true,
"not_available": 3392,
"scored_n": 14597,
"left_out": 3392,
"not_stated": 0
},
{
"key": "collab",
"label": "Multi-centre collaboration",
"blurb": "How many institutions took part. Work repeated across several centres is harder to get by chance.",
"avg": 1.34,
"avg_text": "1.3",
"max": 3,
"pct": 44.7,
"pct_text": "44.7",
"colour": "#D09447",
"typical_points": 1,
"typical_count": 4897,
"typical_detail": "OpenAlex lists 2 institutions in 1 country",
"typical_example": "Loneliness and social isolation among informal carers of individuals with dementia: A systematic review and meta-analysis",
"typical_example_idx": 109,
"modal_points": 2,
"modal_count": 5283,
"modal_detail": "OpenAlex lists 4 institutions in 1 country",
"modal_is_nearest": false,
"not_available": 2851,
"scored_n": 15138,
"left_out": 2851,
"not_stated": 0
},
{
"key": "indexed",
"label": "Indexed in PubMed",
"blurb": "Whether PubMed indexes it, or failing that it has a DOI, so a reader can find and check it.",
"avg": 1.93,
"avg_text": "1.9",
"max": 2,
"pct": 96.4,
"pct_text": "96.4",
"colour": "#6F6A63",
"typical_points": 2,
"typical_count": 16782,
"typical_detail": "Indexed in PubMed (PMID 31413141)",
"typical_example": "The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer's disease risk",
"typical_example_idx": 1080,
"modal_points": 2,
"modal_count": 16782,
"modal_detail": "Indexed in PubMed (PMID 31413141)",
"modal_is_nearest": true,
"not_available": 96,
"scored_n": 17989,
"left_out": 0,
"not_stated": 96
},
{
"key": "open",
"label": "Free to read",
"blurb": "Whether anyone can read the full paper for free. This is about access, not quality.",
"avg": 0.82,
"avg_text": "0.8",
"max": 2,
"pct": 41.1,
"pct_text": "41.1",
"colour": "#A8A29A",
"typical_points": 0,
"typical_count": 10389,
"typical_detail": "Behind a paywall — scores zero",
"typical_example": "Two Randomized Phase 3 Studies of Aducanumab in Early Alzheimer's Disease",
"typical_example_idx": 20,
"modal_points": 0,
"modal_count": 10389,
"modal_detail": "Behind a paywall — scores zero",
"modal_is_nearest": true,
"not_available": 364,
"scored_n": 17625,
"left_out": 364,
"not_stated": 0
}
],
"table": {
"columns": [
"Component",
"Average earned",
"Maximum",
"Share of the maximum",
"Studies scored on it",
"Studies with no data (left out)"
],
"rows": [
[
"Journal tier",
"7.4",
10,
"74.1%",
"17,989",
"0"
],
[
"Journal's citation record",
"2.3",
4,
"56.9%",
"14,649",
"3,340"
],
[
"Study design",
"2.5",
12,
"21.2%",
"17,989",
"0"
],
[
"Strength of evidence",
"1.9",
5,
"38.5%",
"17,732",
"257"
],
[
"Peer-review validation",
"9.9",
10,
"99.2%",
"17,989",
"0"
],
[
"How recent",
"2.5",
5,
"50.7%",
"17,985",
"4"
],
[
"Sample size",
"0.8",
4,
"20%",
"17,989",
"0"
],
[
"Effect reported",
"0.5",
3,
"15.7%",
"17,989",
"0"
],
[
"Studied in people",
"1.2",
3,
"41.1%",
"17,989",
"0"
],
[
"Randomised / blinded",
"0.1",
2,
"4.6%",
"17,989",
"0"
],
[
"Times cited",
"3.8",
7,
"54.4%",
"15,000",
"2,989"
],
[
"Citations per year",
"2.5",
5,
"49.9%",
"14,996",
"2,993"
],
[
"Impact for its field and year",
"3.2",
6,
"52.8%",
"14,744",
"3,245"
],
[
"Cited by studies here",
"1.4",
6,
"23.9%",
"15,249",
"2,740"
],
[
"Still being cited",
"1.7",
4,
"41.5%",
"15,000",
"2,989"
],
[
"Senior author's track record",
"2.6",
4,
"66.4%",
"13,459",
"4,530"
],
[
"Institution's track record",
"1.4",
3,
"47.5%",
"14,597",
"3,392"
],
[
"Multi-centre collaboration",
"1.3",
3,
"44.7%",
"15,138",
"2,851"
],
[
"Indexed in PubMed",
"1.9",
2,
"96.4%",
"17,989",
"0"
],
[
"Free to read",
"0.8",
2,
"41.1%",
"17,625",
"364"
]
]
}
},
{
"id": "fig-cat",
"title": "Which subjects rest on stronger evidence",
"subtitle": "Each subject's median score, with the middle half of its studies as a bar and its full range as a line.",
"svg": "",
"caption": "n = 17989 studies in 32 subjects, counted from the scored library. The bar is the interquartile range — a quarter of the subject's studies score below it and a quarter above. A high median means the studies we carry on that subject are strong ones, not that the subject itself is settled.",
"table": {
"columns": [
"Subject",
"Studies",
"Lowest",
"25th percentile",
"Median",
"75th percentile",
"Highest",
"Peer-reviewed"
],
"rows": [
[
"Clinical trials",
22,
16,
"58.8",
"64",
"72.8",
81,
17
],
[
"Treatments",
809,
10,
"45",
"58",
"66",
85,
795
],
[
"How common it is",
493,
16,
"51",
"58",
"64",
87,
476
],
[
"Laboratory science",
46,
12,
"49.2",
"56.5",
"63",
81,
43
],
[
"Prevention and risk",
872,
16,
"48",
"56",
"66",
88,
861
],
[
"Getting a diagnosis",
781,
16,
"48",
"55",
"61",
79,
770
],
[
"Long-term cohort studies",
512,
16,
"49",
"54",
"60",
81,
510
],
[
"Genetics",
802,
16,
"44",
"52",
"59",
84,
773
],
[
"Caregiving",
677,
16,
"45",
"52",
"62",
83,
673
],
[
"Prevention trials",
662,
28,
"41",
"52",
"67",
88,
662
],
[
"Lewy body dementia",
543,
16,
"47",
"51",
"56",
71,
538
],
[
"Disparities",
689,
16,
"44",
"50",
"58",
79,
679
],
[
"Mild cognitive impairment",
667,
16,
"45",
"50",
"57.5",
78,
666
],
[
"Brain scans and imaging",
624,
16,
"45",
"50",
"56",
77,
611
],
[
"Cognitive tests and assessment",
560,
10,
"44",
"50",
"56",
83,
557
],
[
"Brain tissue and pathology",
447,
16,
"45",
"50",
"56",
80,
441
],
[
"Costs and economics",
40,
16,
"47",
"49.5",
"62",
74,
39
],
[
"Biomarkers",
796,
16,
"41",
"49",
"60",
84,
771
],
[
"TREM2 and immune genetics",
580,
35,
"45",
"49",
"54",
85,
580
],
[
"Digital health tools",
739,
16,
"42",
"48",
"54",
79,
734
],
[
"Vascular contributions",
379,
30,
"40",
"47",
"55",
84,
379
],
[
"Inflammation and the immune system",
659,
29,
"42",
"46",
"51",
82,
659
],
[
"Tau biomarkers",
447,
16,
"39",
"46",
"53",
77,
435
],
[
"Risk factors",
979,
11,
"37",
"45",
"53",
88,
959
],
[
"Risk genes beyond APOE",
630,
16,
"41",
"45",
"48",
69,
623
],
[
"Clinical safety",
569,
24,
"39",
"45",
"57",
86,
569
],
[
"End-of-life care",
698,
15,
"38",
"44",
"53",
86,
696
],
[
"Hippocampus size on brain scans",
492,
36,
"36",
"43",
"52",
84,
492
],
[
"Disease mechanisms",
666,
25,
"36",
"40",
"45",
74,
666
],
[
"Down syndrome and Alzheimer's",
538,
16,
"35",
"39",
"44",
68,
526
],
[
"Health systems and care delivery",
477,
9,
"33",
"39",
"47",
69,
467
],
[
"Drug development",
94,
16,
"34",
"39",
"47.8",
69,
90
]
]
}
},
{
"id": "fig-mix",
"title": "What kinds of study each subject rests on",
"subtitle": "Laboratory science is the most observational: 20 of its 46 studies watch what happens rather than test a change.",
"svg": "",
"caption": "n = 17989 studies. Each bar is one subject, split by the study design each record states, which is what the score reads. Bars are shares of that subject, so a short subject and a long one are comparable; the study count is printed at the end of every bar, and subjects with fewer than 5 studies are flagged. \"Other or not recorded\" is computer-modelling studies plus records with no design in them, which score zero for design rather than being guessed at.",
"table": {
"columns": [
"Subject",
"Studies",
"Systematic review",
"Meta-analysis",
"Randomised controlled trial",
"Phase 2 or phase 3 trial",
"Cohort study",
"Case-control",
"Cross-sectional",
"Other or not recorded"
],
"rows": [
[
"Laboratory science",
46,
0,
0,
1,
1,
15,
4,
1,
24
],
[
"Costs and economics",
40,
2,
0,
6,
0,
10,
0,
3,
19
],
[
"Biomarkers",
796,
0,
9,
0,
1,
24,
0,
108,
654
],
[
"Disparities",
689,
0,
16,
0,
0,
0,
0,
64,
609
],
[
"Vascular contributions",
379,
0,
12,
0,
0,
0,
0,
34,
333
],
[
"Long-term cohort studies",
512,
0,
13,
0,
0,
0,
0,
45,
454
],
[
"Genetics",
802,
0,
27,
1,
0,
14,
11,
44,
705
],
[
"Caregiving",
677,
2,
40,
13,
0,
2,
0,
55,
565
],
[
"End-of-life care",
698,
0,
6,
0,
0,
0,
0,
58,
634
],
[
"How common it is",
493,
0,
20,
0,
0,
12,
0,
28,
433
],
[
"Tau biomarkers",
447,
0,
5,
0,
0,
0,
0,
36,
406
],
[
"Cognitive tests and assessment",
560,
0,
9,
0,
0,
0,
0,
45,
506
],
[
"Brain scans and imaging",
624,
0,
3,
0,
0,
0,
0,
50,
571
],
[
"Risk factors",
979,
0,
36,
0,
0,
0,
0,
76,
867
],
[
"Prevention and risk",
872,
1,
74,
12,
1,
45,
0,
21,
718
],
[
"Hippocampus size on brain scans",
492,
0,
19,
0,
0,
0,
0,
37,
436
],
[
"Getting a diagnosis",
781,
4,
17,
2,
0,
5,
0,
47,
706
],
[
"Health systems and care delivery",
477,
0,
5,
0,
0,
0,
0,
31,
441
],
[
"Mild cognitive impairment",
667,
0,
12,
0,
0,
0,
0,
33,
622
],
[
"Prevention trials",
662,
0,
35,
0,
0,
0,
0,
25,
602
],
[
"Digital health tools",
739,
0,
11,
0,
0,
0,
0,
26,
702
],
[
"Down syndrome and Alzheimer's",
538,
0,
1,
0,
0,
0,
0,
18,
519
],
[
"Drug development",
94,
0,
4,
0,
0,
0,
0,
3,
87
],
[
"Brain tissue and pathology",
447,
0,
7,
0,
0,
0,
0,
12,
428
],
[
"Clinical safety",
569,
0,
24,
0,
0,
0,
0,
14,
531
],
[
"Treatments",
809,
2,
18,
3,
4,
6,
1,
9,
766
],
[
"Disease mechanisms",
666,
0,
6,
0,
0,
0,
0,
10,
650
],
[
"Lewy body dementia",
543,
0,
0,
0,
0,
0,
0,
8,
535
],
[
"TREM2 and immune genetics",
580,
0,
23,
0,
0,
0,
0,
8,
549
],
[
"Risk genes beyond APOE",
630,
0,
7,
0,
0,
0,
0,
4,
619
],
[
"Inflammation and the immune system",
659,
0,
12,
0,
0,
0,
0,
3,
644
],
[
"Clinical trials",
22,
0,
0,
2,
17,
0,
0,
0,
3
]
]
},
"buckets": [
{
"key": "systematic-review",
"label": "Systematic review",
"colour": "#3B1B57",
"total": 11
},
{
"key": "meta-analysis",
"label": "Meta-analysis",
"colour": "#4F2E6F",
"total": 471
},
{
"key": "rct",
"label": "Randomised controlled trial",
"colour": "#654287",
"total": 40
},
{
"key": "trial",
"label": "Phase 2 or phase 3 trial",
"colour": "#7A579F",
"total": 24
},
{
"key": "cohort",
"label": "Cohort study",
"colour": "#906EB4",
"total": 133
},
{
"key": "case-control",
"label": "Case-control",
"colour": "#A587C8",
"total": 16
},
{
"key": "cross-sectional",
"label": "Cross-sectional",
"colour": "#BBA0D9",
"total": 956
},
{
"key": "other",
"label": "Other or not recorded",
"colour": "#8C8378",
"total": 16338
}
]
}
]
}