{"data_date":"2026-11-08","library_size":29380,"matched_against":"each record's title and abstract (summary field), case-insensitive","n":293,"page":"https://alzhub.org/answers/hearing-loss-and-dementia","query":"title or abstract mentions \"hearing loss\", \"hearing aid(s)\", \"hearing impairment\", \"hearing intervention\", \"presbycusis\" or \"audiometry\"","studies":[{"alzhub_score":73,"alzhub_url":"https://alzhub.org/study/hearing-intervention-versus-health-education-control-to-reduce-4ecff333","doi":null,"journal":"The Lancet","n_participants":977,"pmid":null,"source_url":"https://pubmed.ncbi.nlm.nih.gov/37478886/","study_design":"RCT","title":"Hearing intervention versus health education control to reduce cognitive decline in older adults with hearing loss in the USA (ACHIEVE): a multicentre, randomised controlled trial","title_match":true,"year":2023},{"alzhub_score":66,"alzhub_url":"https://alzhub.org/study/a-comprehensive-evaluation-on-the-associations-between-hearing-and-39506811","doi":"10.1186/s12916-024-03748-7","journal":"BMC Medicine","n_participants":937908,"pmid":"39506811","source_url":"https://pubmed.ncbi.nlm.nih.gov/39506811/","study_design":"meta-analysis","title":"A comprehensive evaluation on the associations between hearing and vision impairments and risk of all-cause and cause-specific dementia: results from cohort study, meta-analysis and Mendelian randomization study","title_match":false,"year":2024},{"alzhub_score":72,"alzhub_url":"https://alzhub.org/study/risk-factors-for-young-onset-dementia-in-the-uk-biobank-38147328","doi":"10.1001/jamaneurol.2023.4929","journal":"JAMA Neurology","n_participants":356052,"pmid":"38147328","source_url":"https://pubmed.ncbi.nlm.nih.gov/38147328/","study_design":"cohort","title":"Risk Factors for Young-Onset Dementia in the UK Biobank","title_match":false,"year":2024},{"alzhub_score":79,"alzhub_url":"https://alzhub.org/study/association-of-hearing-aids-and-cochlear-implants-with-cognitive-36469314","doi":"10.1001/jamaneurol.2022.4427","journal":"JAMA Neurology","n_participants":137484,"pmid":"36469314","source_url":"https://pubmed.ncbi.nlm.nih.gov/36469314/","study_design":"meta-analysis","title":"Association of Hearing Aids and Cochlear Implants With Cognitive Decline and Dementia: A Systematic Review and Meta-analysis","title_match":true,"year":2023},{"alzhub_score":70,"alzhub_url":"https://alzhub.org/study/hearing-loss-hearing-aid-use-and-risk-of-dementia-in-older-adults-38175662","doi":"10.1001/jamaoto.2023.3509","journal":"JAMA Otolaryngology-Head & Neck Surgery","n_participants":573088,"pmid":"38175662","source_url":"https://pubmed.ncbi.nlm.nih.gov/38175662/","study_design":"cohort","title":"Hearing Loss, Hearing Aid Use, and Risk of Dementia in Older Adults","title_match":true,"year":2024},{"alzhub_score":61,"alzhub_url":"https://alzhub.org/study/hearing-aid-effectiveness-and-probable-dementia-risk-across-33-42127901","doi":"10.1016/j.xcrm.2026.102802","journal":"Cell Reports Medicine","n_participants":61089,"pmid":"42127901","source_url":"https://pubmed.ncbi.nlm.nih.gov/42127901/","study_design":"cohort","title":"Hearing aid effectiveness and probable dementia risk across 33 countries: A pooled analysis of seven cohorts","title_match":true,"year":2026},{"alzhub_score":56,"alzhub_url":"https://alzhub.org/study/population-attributable-fractions-of-a-wide-range-of-peripheral-41559195","doi":"10.1038/s41562-025-02392-2","journal":"Nature human behaviour","n_participants":null,"pmid":"41559195","source_url":"https://pubmed.ncbi.nlm.nih.gov/41559195/","study_design":"meta-analysis","title":"Population attributable fractions of a wide range of peripheral diseases for the burden of dementia","title_match":false,"year":2026},{"alzhub_score":53,"alzhub_url":"https://alzhub.org/study/electronic-health-records-to-test-multimorbidity-influences-to-plasma-41447112","doi":"10.1002/ana.78114","journal":"Annals of neurology","n_participants":617,"pmid":"41447112","source_url":"https://pubmed.ncbi.nlm.nih.gov/41447112/","study_design":"cross-sectional","title":"Electronic Health Records to Test Multimorbidity Influences to Plasma Biomarker Interpretation for Alzheimer's Disease","title_match":false,"year":2026},{"alzhub_score":60,"alzhub_url":"https://alzhub.org/study/do-hearing-aids-influence-behavioral-and-psychological-symptoms-of-28269769","doi":"10.3233/jad-160792","journal":"Journal of Alzheimer's disease : JAD","n_participants":null,"pmid":"28269769","source_url":"https://pubmed.ncbi.nlm.nih.gov/28269769/","study_design":null,"title":"Do Hearing Aids Influence Behavioral and Psychological Symptoms of Dementia and Quality of Life in Hearing Impaired Alzheimer's Disease Patients and Their Caregivers?","title_match":true,"year":2017},{"alzhub_score":44,"alzhub_url":"https://alzhub.org/study/design-and-methods-of-the-early-age-related-hearing-loss-38728564","doi":"10.1097/mao.0000000000004093","journal":"Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology","n_participants":null,"pmid":"38728564","source_url":"https://pubmed.ncbi.nlm.nih.gov/38728564/","study_design":null,"title":"Design and Methods of the Early Age-Related Hearing Loss Investigation Randomized Controlled Trial","title_match":true,"year":2024},{"alzhub_score":71,"alzhub_url":"https://alzhub.org/study/hearing-loss-and-incident-dementia-21320988","doi":"10.1001/archneurol.2010.362","journal":"Archives of neurology","n_participants":639,"pmid":"21320988","source_url":"https://pubmed.ncbi.nlm.nih.gov/21320988/","study_design":"longitudinal study","title":"Hearing loss and incident dementia","title_match":true,"year":2011},{"alzhub_score":71,"alzhub_url":"https://alzhub.org/study/association-of-age-related-hearing-loss-with-cognitive-function-29222544","doi":"10.1001/jamaoto.2017.2513","journal":"JAMA otolaryngology-- head & neck surgery","n_participants":null,"pmid":"29222544","source_url":"https://pubmed.ncbi.nlm.nih.gov/29222544/","study_design":"systematic review","title":"Association of Age-Related Hearing Loss With Cognitive Function, Cognitive Impairment, and Dementia: A Systematic Review and Meta-analysis","title_match":true,"year":2018},{"alzhub_score":59,"alzhub_url":"https://alzhub.org/study/hearing-impairment-and-incident-dementia-and-cognitive-decline-in-27071780","doi":"10.1093/gerona/glw069","journal":"The journals of gerontology. Series A, Biological sciences and medical sciences","n_participants":null,"pmid":"27071780","source_url":"https://pubmed.ncbi.nlm.nih.gov/27071780/","study_design":null,"title":"Hearing Impairment and Incident Dementia and Cognitive Decline in Older Adults: The Health ABC Study","title_match":true,"year":2017},{"alzhub_score":52,"alzhub_url":"https://alzhub.org/study/sensation-and-psychiatry-linking-age-related-hearing-loss-to-late-29202654","doi":"10.1176/appi.ajp.2017.17040423","journal":"The American journal of psychiatry","n_participants":null,"pmid":"29202654","source_url":"https://pubmed.ncbi.nlm.nih.gov/29202654/","study_design":null,"title":"Sensation and Psychiatry: Linking Age-Related Hearing Loss to Late-Life Depression and Cognitive Decline","title_match":true,"year":2018},{"alzhub_score":64,"alzhub_url":"https://alzhub.org/study/mortality-after-osteoporotic-hip-fracture-incidence-trends-and-31272470","doi":"10.1186/s13018-019-1226-6","journal":"Journal of orthopaedic surgery and research","n_participants":3992,"pmid":"31272470","source_url":"https://pubmed.ncbi.nlm.nih.gov/31272470/","study_design":"cohort study","title":"Mortality after osteoporotic hip fracture: incidence, trends, and associated factors","title_match":false,"year":2019},{"alzhub_score":84,"alzhub_url":"https://alzhub.org/study/hearing-intervention-versus-health-education-control-to-reduce-37478886","doi":"10.1016/s0140-6736(23)01406-x","journal":"Lancet (London, England)","n_participants":858,"pmid":"37478886","source_url":"https://pubmed.ncbi.nlm.nih.gov/37478886/","study_design":"randomized controlled trial","title":"Hearing intervention versus health education control to reduce cognitive decline in older adults with hearing loss in the USA (ACHIEVE): a multicentre, randomised controlled trial","title_match":true,"year":2023},{"alzhub_score":75,"alzhub_url":"https://alzhub.org/study/population-attributable-fractions-for-risk-factors-for-dementia-in-31000129","doi":"10.1016/s2214-109x(19)30074-9","journal":"The Lancet. Global health","n_participants":2162,"pmid":"31000129","source_url":"https://pubmed.ncbi.nlm.nih.gov/31000129/","study_design":"meta-analysis","title":"Population attributable fractions for risk factors for dementia in low-income and middle-income countries: an analysis using cross-sectional survey data","title_match":false,"year":2019},{"alzhub_score":48,"alzhub_url":"https://alzhub.org/study/age-related-hearing-loss-30291149","doi":"10.1101/cshperspect.a033217","journal":"Cold Spring Harbor perspectives in medicine","n_participants":null,"pmid":"30291149","source_url":"https://pubmed.ncbi.nlm.nih.gov/30291149/","study_design":null,"title":"Age-Related Hearing Loss","title_match":true,"year":2019},{"alzhub_score":56,"alzhub_url":"https://alzhub.org/study/how-can-hearing-loss-cause-dementia-32871106","doi":"10.1016/j.neuron.2020.08.003","journal":"Neuron","n_participants":null,"pmid":"32871106","source_url":"https://pubmed.ncbi.nlm.nih.gov/32871106/","study_design":null,"title":"How Can Hearing Loss Cause Dementia?","title_match":true,"year":2020},{"alzhub_score":64,"alzhub_url":"https://alzhub.org/study/relationship-of-hearing-loss-and-dementia-a-prospective-population-24662628","doi":"10.1097/mao.0000000000000313","journal":"Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology","n_participants":4463,"pmid":"24662628","source_url":"https://pubmed.ncbi.nlm.nih.gov/24662628/","study_design":"cohort study","title":"Relationship of hearing loss and dementia: a prospective, population-based study","title_match":true,"year":2014},{"alzhub_score":49,"alzhub_url":"https://alzhub.org/study/aging-and-hearing-health-the-life-course-approach-26994265","doi":"10.1093/geront/gnw033","journal":"The Gerontologist","n_participants":null,"pmid":"26994265","source_url":"https://pubmed.ncbi.nlm.nih.gov/26994265/","study_design":null,"title":"Aging and Hearing Health: The Life-course Approach","title_match":false,"year":2016},{"alzhub_score":47,"alzhub_url":"https://alzhub.org/study/the-effects-of-age-related-hearing-loss-on-the-brain-and-cognitive-32826080","doi":"10.1016/j.tins.2020.07.005","journal":"Trends in neurosciences","n_participants":null,"pmid":"32826080","source_url":"https://pubmed.ncbi.nlm.nih.gov/32826080/","study_design":null,"title":"The Effects of Age-Related Hearing Loss on the Brain and Cognitive Function","title_match":true,"year":2020},{"alzhub_score":48,"alzhub_url":"https://alzhub.org/study/age-related-hearing-loss-and-cognitive-decline-the-potential-30177417","doi":"10.1016/j.anl.2018.08.010","journal":"Auris, nasus, larynx","n_participants":null,"pmid":"30177417","source_url":"https://pubmed.ncbi.nlm.nih.gov/30177417/","study_design":null,"title":"Age-related hearing loss and cognitive decline - The potential mechanisms linking the two","title_match":true,"year":2019},{"alzhub_score":62,"alzhub_url":"https://alzhub.org/study/hearing-loss-as-a-risk-factor-for-dementia-a-systematic-review-28894825","doi":"10.1002/lio2.65","journal":"Laryngoscope investigative otolaryngology","n_participants":null,"pmid":"28894825","source_url":"https://pubmed.ncbi.nlm.nih.gov/28894825/","study_design":"systematic review","title":"Hearing loss as a risk factor for dementia: A systematic review","title_match":true,"year":2017},{"alzhub_score":65,"alzhub_url":"https://alzhub.org/study/age-related-sensory-impairments-and-risk-of-cognitive-impairment-27611845","doi":"10.1111/jgs.14308","journal":"Journal of the American Geriatrics Society","n_participants":1884,"pmid":"27611845","source_url":"https://pubmed.ncbi.nlm.nih.gov/27611845/","study_design":"longitudinal study","title":"Age-Related Sensory Impairments and Risk of Cognitive Impairment","title_match":false,"year":2016},{"alzhub_score":48,"alzhub_url":"https://alzhub.org/study/age-related-hearing-impairment-a-risk-factor-and-frailty-marker-for-25686757","doi":"10.1038/nrneurol.2015.12","journal":"Nature reviews. Neurology","n_participants":null,"pmid":"25686757","source_url":"https://pubmed.ncbi.nlm.nih.gov/25686757/","study_design":null,"title":"Age-related hearing impairment-a risk factor and frailty marker for dementia and AD","title_match":true,"year":2015},{"alzhub_score":42,"alzhub_url":"https://alzhub.org/study/age-related-hearing-loss-and-tinnitus-dementia-risk-and-auditory-31557539","doi":"10.1016/j.arr.2019.100963","journal":"Ageing research reviews","n_participants":null,"pmid":"31557539","source_url":"https://pubmed.ncbi.nlm.nih.gov/31557539/","study_design":null,"title":"Age-related hearing loss and tinnitus, dementia risk, and auditory amplification outcomes","title_match":true,"year":2019},{"alzhub_score":56,"alzhub_url":"https://alzhub.org/study/olfaction-and-the-5-year-incidence-of-cognitive-impairment-in-an-18662205","doi":"10.1111/j.1532-5415.2008.01826.x","journal":"Journal of the American Geriatrics Society","n_participants":null,"pmid":"18662205","source_url":"https://pubmed.ncbi.nlm.nih.gov/18662205/","study_design":"longitudinal study","title":"Olfaction and the 5-year incidence of cognitive impairment in an epidemiological study of older adults","title_match":false,"year":2008},{"alzhub_score":65,"alzhub_url":"https://alzhub.org/study/the-relationship-between-hearing-impairment-and-cognitive-function-a-26670203","doi":"10.1111/coa.12607","journal":"Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery","n_participants":602,"pmid":"26670203","source_url":"https://pubmed.ncbi.nlm.nih.gov/26670203/","study_design":"systematic review","title":"The relationship between hearing impairment and cognitive function: a meta-analysis in adults","title_match":true,"year":2016},{"alzhub_score":48,"alzhub_url":"https://alzhub.org/study/gwas-identifies-44-independent-associated-genomic-loci-for-self-31564434","doi":"10.1016/j.ajhg.2019.09.008","journal":"American journal of human genetics","n_participants":null,"pmid":"31564434","source_url":"https://pubmed.ncbi.nlm.nih.gov/31564434/","study_design":null,"title":"GWAS Identifies 44 Independent Associated Genomic Loci for Self-Reported Adult Hearing Difficulty in UK Biobank","title_match":false,"year":2019},{"alzhub_score":69,"alzhub_url":"https://alzhub.org/study/how-can-dementia-and-disability-be-prevented-in-older-adults-where-33314384","doi":"10.1111/joim.13227","journal":"Journal of internal medicine","n_participants":null,"pmid":"33314384","source_url":"https://pubmed.ncbi.nlm.nih.gov/33314384/","study_design":"randomized controlled trial","title":"How can dementia and disability be prevented in older adults: where are we today and where are we going?","title_match":false,"year":2021},{"alzhub_score":72,"alzhub_url":"https://alzhub.org/study/hearing-loss-and-the-risk-of-dementia-in-later-life-29704910","doi":"10.1016/j.maturitas.2018.03.004","journal":"Maturitas","n_participants":6948,"pmid":"29704910","source_url":"https://pubmed.ncbi.nlm.nih.gov/29704910/","study_design":"systematic review","title":"Hearing loss and the risk of dementia in later life","title_match":true,"year":2018},{"alzhub_score":53,"alzhub_url":"https://alzhub.org/study/central-auditory-dysfunction-cognitive-dysfunction-and-dementia-in-8630210","doi":"10.1001/archotol.1996.01890140047010","journal":"Archives of otolaryngology--head & neck surgery","n_participants":null,"pmid":"8630210","source_url":"https://pubmed.ncbi.nlm.nih.gov/8630210/","study_design":"cohort study","title":"Central auditory dysfunction, cognitive dysfunction, and dementia in older people","title_match":false,"year":1996},{"alzhub_score":43,"alzhub_url":"https://alzhub.org/study/associations-between-self-reported-sensory-impairment-and-risk-of-30977823","doi":"10.1093/geronb/gbz043","journal":"The journals of gerontology. Series B, Psychological sciences and social sciences","n_participants":null,"pmid":"30977823","source_url":"https://pubmed.ncbi.nlm.nih.gov/30977823/","study_design":null,"title":"Associations Between Self-Reported Sensory Impairment and Risk of Cognitive Decline and Impairment in the Health and Retirement Study Cohort","title_match":false,"year":2020},{"alzhub_score":67,"alzhub_url":"https://alzhub.org/study/association-of-midlife-hearing-impairment-with-late-life-temporal-31268512","doi":"10.1001/jamaoto.2019.1610","journal":"JAMA otolaryngology-- head & neck surgery","n_participants":194,"pmid":"31268512","source_url":"https://pubmed.ncbi.nlm.nih.gov/31268512/","study_design":"cohort study","title":"Association of Midlife Hearing Impairment With Late-Life Temporal Lobe Volume Loss","title_match":true,"year":2019},{"alzhub_score":64,"alzhub_url":"https://alzhub.org/study/association-of-subclinical-hearing-loss-with-cognitive-performance-31725853","doi":"10.1001/jamaoto.2019.3375","journal":"JAMA otolaryngology-- head & neck surgery","n_participants":5190,"pmid":"31725853","source_url":"https://pubmed.ncbi.nlm.nih.gov/31725853/","study_design":"cross-sectional","title":"Association of Subclinical Hearing Loss With Cognitive Performance","title_match":true,"year":2020},{"alzhub_score":57,"alzhub_url":"https://alzhub.org/study/multiple-sensory-impairment-is-associated-with-increased-risk-of-30452551","doi":"10.1093/gerona/gly264","journal":"The journals of gerontology. Series A, Biological sciences and medical sciences","n_participants":1810,"pmid":"30452551","source_url":"https://pubmed.ncbi.nlm.nih.gov/30452551/","study_design":null,"title":"Multiple Sensory Impairment Is Associated With Increased Risk of Dementia Among Black and White Older Adults","title_match":false,"year":2019},{"alzhub_score":52,"alzhub_url":"https://alzhub.org/study/cognitive-frailty-in-china-results-from-china-comprehensive-geriatric-29104866","doi":"10.3389/fmed.2017.00174","journal":"Frontiers in medicine","n_participants":5708,"pmid":"29104866","source_url":"https://pubmed.ncbi.nlm.nih.gov/29104866/","study_design":null,"title":"Cognitive Frailty in China: Results from China Comprehensive Geriatric Assessment Study","title_match":false,"year":2017},{"alzhub_score":61,"alzhub_url":"https://alzhub.org/study/risk-factors-for-dementia-in-brazil-differences-by-region-and-race-36326095","doi":"10.1002/alz.12820","journal":"Alzheimer's & dementia : the journal of the Alzheimer's Association","n_participants":null,"pmid":"36326095","source_url":"https://pubmed.ncbi.nlm.nih.gov/36326095/","study_design":"longitudinal study","title":"Risk factors for dementia in Brazil: Differences by region and race","title_match":false,"year":2023},{"alzhub_score":64,"alzhub_url":"https://alzhub.org/study/health-status-and-risk-profiles-for-brain-aging-of-rural-dwelling-35441085","doi":"10.1002/trc2.12254","journal":"Alzheimer's & dementia (New York, N. Y.)","n_participants":5765,"pmid":"35441085","source_url":"https://pubmed.ncbi.nlm.nih.gov/35441085/","study_design":null,"title":"Health status and risk profiles for brain aging of rural-dwelling older adults: Data from the interdisciplinary baseline assessments in MIND-China","title_match":false,"year":2022},{"alzhub_score":44,"alzhub_url":"https://alzhub.org/study/late-neurological-complications-after-prophylactic-cranial-2153764","doi":"10.1200/jco.1990.8.2.215","journal":"Journal of clinical oncology : official journal of the American Society of Clinical Oncology","n_participants":14,"pmid":"2153764","source_url":"https://pubmed.ncbi.nlm.nih.gov/2153764/","study_design":null,"title":"Late neurological complications after prophylactic cranial irradiation in patients with small-cell lung cancer: the Toronto experience","title_match":false,"year":1990},{"alzhub_score":61,"alzhub_url":"https://alzhub.org/study/hearing-loss-and-cognition-in-the-baltimore-longitudinal-study-of-21728425","doi":"10.1037/a0024238","journal":"Neuropsychology","n_participants":347,"pmid":"21728425","source_url":"https://pubmed.ncbi.nlm.nih.gov/21728425/","study_design":"cross-sectional","title":"Hearing loss and cognition in the Baltimore Longitudinal Study of Aging","title_match":true,"year":2011},{"alzhub_score":64,"alzhub_url":"https://alzhub.org/study/association-of-hearing-impairment-with-brain-volume-changes-in-older-24412398","doi":"10.1016/j.neuroimage.2013.12.059","journal":"NeuroImage","n_participants":126,"pmid":"24412398","source_url":"https://pubmed.ncbi.nlm.nih.gov/24412398/","study_design":"cross-sectional","title":"Association of hearing impairment with brain volume changes in older adults","title_match":true,"year":2014},{"alzhub_score":42,"alzhub_url":"https://alzhub.org/study/compensatory-changes-in-cortical-resource-allocation-in-adults-with-24478637","doi":"10.3389/fnsys.2013.00071","journal":"Frontiers in systems neuroscience","n_participants":null,"pmid":"24478637","source_url":"https://pubmed.ncbi.nlm.nih.gov/24478637/","study_design":null,"title":"Compensatory changes in cortical resource allocation in adults with hearing loss","title_match":true,"year":2013},{"alzhub_score":49,"alzhub_url":"https://alzhub.org/study/the-effect-of-hearing-aid-use-on-cognition-in-older-adults-can-we-31963547","doi":"10.3390/jcm9010254","journal":"Journal of clinical medicine","n_participants":null,"pmid":"31963547","source_url":"https://pubmed.ncbi.nlm.nih.gov/31963547/","study_design":null,"title":"The Effect of Hearing Aid Use on Cognition in Older Adults: Can We Delay Decline or Even Improve Cognitive Function?","title_match":true,"year":2020},{"alzhub_score":61,"alzhub_url":"https://alzhub.org/study/long-term-cognitive-prognosis-of-profoundly-deaf-older-adults-after-30091185","doi":"10.1111/jgs.15445","journal":"Journal of the American Geriatrics Society","n_participants":70,"pmid":"30091185","source_url":"https://pubmed.ncbi.nlm.nih.gov/30091185/","study_design":"longitudinal study","title":"Long-Term Cognitive Prognosis of Profoundly Deaf Older Adults After Hearing Rehabilitation Using Cochlear Implants","title_match":true,"year":2018},{"alzhub_score":49,"alzhub_url":"https://alzhub.org/study/the-hearing-hippocampus-35870677","doi":"10.1016/j.pneurobio.2022.102326","journal":"Progress in neurobiology","n_participants":null,"pmid":"35870677","source_url":"https://pubmed.ncbi.nlm.nih.gov/35870677/","study_design":null,"title":"The hearing hippocampus","title_match":false,"year":2022},{"alzhub_score":52,"alzhub_url":"https://alzhub.org/study/the-age-related-central-auditory-processing-disorder-silent-31258467","doi":"10.3389/fnins.2019.00619","journal":"Frontiers in neuroscience","n_participants":null,"pmid":"31258467","source_url":"https://pubmed.ncbi.nlm.nih.gov/31258467/","study_design":"longitudinal study","title":"The Age-Related Central Auditory Processing Disorder: Silent Impairment of the Cognitive Ear","title_match":false,"year":2019},{"alzhub_score":56,"alzhub_url":"https://alzhub.org/study/the-effect-of-cochlear-implants-on-cognitive-function-in-older-adults-31427915","doi":"10.3389/fnins.2019.00789","journal":"Frontiers in neuroscience","n_participants":59,"pmid":"31427915","source_url":"https://pubmed.ncbi.nlm.nih.gov/31427915/","study_design":"longitudinal study","title":"The Effect of Cochlear Implants on Cognitive Function in Older Adults: Initial Baseline and 18-Month Follow Up Results for a Prospective International Longitudinal Study","title_match":false,"year":2019},{"alzhub_score":56,"alzhub_url":"https://alzhub.org/study/speech-in-noise-hearing-impairment-is-associated-with-an-increased-34288382","doi":"10.1002/alz.12416","journal":"Alzheimer's & dementia : the journal of the Alzheimer's Association","n_participants":1285,"pmid":"34288382","source_url":"https://pubmed.ncbi.nlm.nih.gov/34288382/","study_design":null,"title":"Speech-in-noise hearing impairment is associated with an increased risk of incident dementia in 82,039 UK Biobank participants","title_match":true,"year":2022},{"alzhub_score":34,"alzhub_url":"https://alzhub.org/study/central-auditory-processing-in-alzheimer-s-disease-7789674","doi":"10.1097/00003446-199504000-00010","journal":"Ear and hearing","n_participants":null,"pmid":"7789674","source_url":"https://pubmed.ncbi.nlm.nih.gov/7789674/","study_design":null,"title":"Central auditory processing in Alzheimer's disease","title_match":false,"year":1995},{"alzhub_score":48,"alzhub_url":"https://alzhub.org/study/association-between-hearing-loss-and-development-of-dementia-using-36410368","doi":"10.1016/s2666-7568(22)00241-0","journal":"The lancet. Healthy longevity","n_participants":null,"pmid":"36410368","source_url":"https://pubmed.ncbi.nlm.nih.gov/36410368/","study_design":null,"title":"Association between hearing loss and development of dementia using formal behavioural audiometric testing within the Mayo Clinic Study of Aging (MCSA): a prospective population-based study","title_match":true,"year":2022},{"alzhub_score":58,"alzhub_url":"https://alzhub.org/study/data-driven-discovery-of-probable-alzheimer-s-disease-and-related-33083543","doi":"10.1002/lrh2.10246","journal":"Learning health systems","n_participants":273,"pmid":"33083543","source_url":"https://pubmed.ncbi.nlm.nih.gov/33083543/","study_design":"longitudinal study","title":"Data-driven discovery of probable Alzheimer's disease and related dementia subphenotypes using electronic health records","title_match":false,"year":2020},{"alzhub_score":56,"alzhub_url":"https://alzhub.org/study/hearing-loss-treatment-in-older-adults-with-cognitive-impairment-a-30304320","doi":"10.1044/2018_jslhr-h-18-0077","journal":"Journal of speech, language, and hearing research : JSLHR","n_participants":null,"pmid":"30304320","source_url":"https://pubmed.ncbi.nlm.nih.gov/30304320/","study_design":"randomized controlled trial","title":"Hearing Loss Treatment in Older Adults With Cognitive Impairment: A Systematic Review","title_match":true,"year":2018},{"alzhub_score":46,"alzhub_url":"https://alzhub.org/study/occupational-noise-auditory-and-non-auditory-consequences-33276507","doi":"10.3390/ijerph17238963","journal":"International journal of environmental research and public health","n_participants":null,"pmid":"33276507","source_url":"https://pubmed.ncbi.nlm.nih.gov/33276507/","study_design":null,"title":"Occupational Noise: Auditory and Non-Auditory Consequences","title_match":false,"year":2020},{"alzhub_score":45,"alzhub_url":"https://alzhub.org/study/melas-syndrome-clinical-manifestations-pathogenesis-and-treatment-26095523","doi":"10.1016/j.ymgme.2015.06.004","journal":"Molecular genetics and metabolism","n_participants":null,"pmid":"26095523","source_url":"https://pubmed.ncbi.nlm.nih.gov/26095523/","study_design":null,"title":"MELAS syndrome: Clinical manifestations, pathogenesis, and treatment options","title_match":false,"year":2015},{"alzhub_score":61,"alzhub_url":"https://alzhub.org/study/hearing-loss-and-cognition-the-role-of-hearing-aids-social-isolation-25760329","doi":"10.1371/journal.pone.0119616","journal":"PloS one","n_participants":164770,"pmid":"25760329","source_url":"https://pubmed.ncbi.nlm.nih.gov/25760329/","study_design":null,"title":"Hearing loss and cognition: the role of hearing AIDS, social isolation and depression","title_match":true,"year":2015},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/health-care-concerns-and-guidelines-for-adults-with-down-syndrome-10559765","doi":"10.1002/(sici)1096-8628(19990625)89:2<100::aid-ajmg8>3.0.co;2-n","journal":"American journal of medical genetics","n_participants":null,"pmid":"10559765","source_url":"https://pubmed.ncbi.nlm.nih.gov/10559765/","study_design":null,"title":"Health care concerns and guidelines for adults with Down syndrome","title_match":false,"year":1999},{"alzhub_score":40,"alzhub_url":"https://alzhub.org/study/corticonigral-degeneration-with-neuronal-achromasia-presenting-with-7707078","doi":"10.1016/0022-510x(94)90072-8","journal":"Journal of the neurological sciences","n_participants":null,"pmid":"7707078","source_url":"https://pubmed.ncbi.nlm.nih.gov/7707078/","study_design":null,"title":"Corticonigral degeneration with neuronal achromasia presenting with primary progressive aphasia: ultrastructural and immunocytochemical studies","title_match":false,"year":1994},{"alzhub_score":65,"alzhub_url":"https://alzhub.org/study/hearing-impairment-is-associated-with-cognitive-decline-brain-atrophy-36356475","doi":"10.1016/j.ebiom.2022.104336","journal":"EBioMedicine","n_participants":165550,"pmid":"36356475","source_url":"https://pubmed.ncbi.nlm.nih.gov/36356475/","study_design":"cross-sectional","title":"Hearing impairment is associated with cognitive decline, brain atrophy and tau pathology","title_match":true,"year":2022},{"alzhub_score":54,"alzhub_url":"https://alzhub.org/study/age-related-hearing-loss-accelerates-cerebrospinal-fluid-tau-levels-31118310","doi":"10.18632/aging.101971","journal":"Aging","n_participants":null,"pmid":"31118310","source_url":"https://pubmed.ncbi.nlm.nih.gov/31118310/","study_design":"cross-sectional","title":"Age-related hearing loss accelerates cerebrospinal fluid tau levels and brain atrophy: a longitudinal study","title_match":true,"year":2019},{"alzhub_score":16,"alzhub_url":"https://alzhub.org/study/association-between-hearing-aid-use-and-all-cause-and-cause-specific-37062296","doi":"10.1016/s2468-2667(23)00048-8","journal":"The Lancet. Public health","n_participants":25,"pmid":"37062296","source_url":"https://pubmed.ncbi.nlm.nih.gov/37062296/","study_design":"cohort study","title":"Association between hearing aid use and all-cause and cause-specific dementia: an analysis of the UK Biobank cohort","title_match":true,"year":2023},{"alzhub_score":48,"alzhub_url":"https://alzhub.org/study/the-characteristic-features-of-auditory-verbal-hallucinations-in-22499783","doi":"10.1093/schbul/sbs061","journal":"Schizophrenia bulletin","n_participants":null,"pmid":"22499783","source_url":"https://pubmed.ncbi.nlm.nih.gov/22499783/","study_design":null,"title":"The characteristic features of auditory verbal hallucinations in clinical and nonclinical groups: state-of-the-art overview and future directions","title_match":false,"year":2012},{"alzhub_score":28,"alzhub_url":"https://alzhub.org/study/cochlear-implants-now-more-accessible-to-older-adults-a9d2ef8f","doi":"10.1097/01.hj.0000911292.81161.cb","journal":"The Hearing Journal","n_participants":null,"pmid":null,"source_url":"https://doi.org/10.1097/01.hj.0000911292.81161.cb","study_design":null,"title":"Cochlear Implants Now More Accessible to Older Adults","title_match":false,"year":2022},{"alzhub_score":26,"alzhub_url":"https://alzhub.org/study/life-in-balance-35618f91","doi":"10.1044/leader.ftr1.18122013.40","journal":"ASHA Leader","n_participants":null,"pmid":null,"source_url":"https://doi.org/10.1044/leader.ftr1.18122013.40","study_design":null,"title":"Life in Balance","title_match":false,"year":2013},{"alzhub_score":31,"alzhub_url":"https://alzhub.org/study/exploring-the-maze-of-the-cognition-audition-connection-0ce0a339","doi":"10.1097/01.hj.0000406770.64981.d4","journal":"The Hearing Journal","n_participants":null,"pmid":null,"source_url":"https://doi.org/10.1097/01.hj.0000406770.64981.d4","study_design":"longitudinal study","title":"Exploring the maze of the cognition-audition connection","title_match":false,"year":2011},{"alzhub_score":59,"alzhub_url":"https://alzhub.org/study/incident-hearing-loss-and-comorbidity-30419134","doi":"10.1001/jamaoto.2018.2876","journal":"JAMA Otolaryngology\u2013Head & Neck Surgery","n_participants":154,"pmid":"30419134","source_url":"https://pubmed.ncbi.nlm.nih.gov/30419134/","study_design":"cohort study","title":"Incident Hearing Loss and Comorbidity","title_match":true,"year":2018},{"alzhub_score":54,"alzhub_url":"https://alzhub.org/study/understanding-medicare-hearing-loss-and-health-literacy-32744734","doi":"10.1111/jgs.16705","journal":"Journal of the American Geriatrics Society","n_participants":10510,"pmid":"32744734","source_url":"https://pubmed.ncbi.nlm.nih.gov/32744734/","study_design":"cross-sectional","title":"Understanding Medicare: Hearing Loss and Health Literacy","title_match":true,"year":2020},{"alzhub_score":32,"alzhub_url":"https://alzhub.org/study/introduction-of-an-openaccess-nationallevel-u-s-dementia-surveillance-41434796","doi":"10.1002/alz70860_100503","journal":"Alzheimer s & Dementia","n_participants":null,"pmid":"41434796","source_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12725989/","study_design":null,"title":"Introduction of an open\u2010access national\u2010level U.S. dementia surveillance system","title_match":false,"year":2025},{"alzhub_score":32,"alzhub_url":"https://alzhub.org/study/desenvolvimento-de-sistema-baseado-na-internet-para-orientacao-e-38055411","doi":"10.1590/2317-1782/20232022162pt","journal":"CoDAS","n_participants":43,"pmid":"38055411","source_url":"https://pubmed.ncbi.nlm.nih.gov/38055411/","study_design":null,"title":"Desenvolvimento de sistema baseado na internet para orienta\u00e7\u00e3o e telemonitoramento de usu\u00e1rios de pr\u00f3tese auditiva","title_match":false,"year":2023},{"alzhub_score":24,"alzhub_url":"https://alzhub.org/study/coding-options-for-central-auditory-processing-e34a9218","doi":"10.1044/leader.bml.07092002.3","journal":"ASHA Leader","n_participants":null,"pmid":null,"source_url":"https://doi.org/10.1044/leader.bml.07092002.3","study_design":null,"title":"Coding Options for Central Auditory Processing","title_match":false,"year":2002},{"alzhub_score":27,"alzhub_url":"https://alzhub.org/study/economics-of-cochlear-implant-utilization-b70a196b","doi":"10.1097/01.hj.0000602912.91566.64","journal":"The Hearing Journal","n_participants":null,"pmid":null,"source_url":"https://doi.org/10.1097/01.hj.0000602912.91566.64","study_design":null,"title":"Economics of Cochlear Implant Utilization","title_match":false,"year":2019},{"alzhub_score":29,"alzhub_url":"https://alzhub.org/study/development-of-an-internet-based-system-to-guide-and-telemonitor-31536918","doi":"10.1590/2317-1782/20232022162en","journal":"CoDAS","n_participants":43,"pmid":null,"source_url":"https://doi.org/10.1590/2317-1782/20232022162en","study_design":null,"title":"Development of an Internet-based system to guide and telemonitor hearing aid users","title_match":true,"year":2023},{"alzhub_score":40,"alzhub_url":"https://alzhub.org/study/maximizing-annual-wellness-visits-to-promote-hearing-health-aeed8851","doi":"10.1097/01.hj.0000557741.82410.a1","journal":"The Hearing Journal","n_participants":null,"pmid":null,"source_url":"https://doi.org/10.1097/01.hj.0000557741.82410.a1","study_design":"systematic review","title":"Maximizing Annual Wellness Visits to Promote Hearing Health","title_match":false,"year":2019},{"alzhub_score":60,"alzhub_url":"https://alzhub.org/study/geographical-variation-in-dementia-prevalence-across-china-a-38974661","doi":"10.1016/j.lanwpc.2024.101117","journal":"The Lancet Regional Health - Western Pacific","n_participants":17176,"pmid":"38974661","source_url":"https://pubmed.ncbi.nlm.nih.gov/38974661/","study_design":"longitudinal study","title":"Geographical variation in dementia prevalence across China: a geospatial analysis","title_match":false,"year":2024},{"alzhub_score":61,"alzhub_url":"https://alzhub.org/study/global-regional-and-national-incidence-prevalence-and-years-lived-28919117","doi":"10.1016/s0140-6736(17)32154-2","journal":"The Lancet","n_participants":null,"pmid":"28919117","source_url":"https://pubmed.ncbi.nlm.nih.gov/28919117/","study_design":null,"title":"Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990\u20132016: a systematic analysis for the Global Burden of Disease Study 2016","title_match":false,"year":2017},{"alzhub_score":58,"alzhub_url":"https://alzhub.org/study/disparities-in-brain-health-comorbidity-management-in-intracerebral-37360335","doi":"10.3389/fneur.2023.1194810","journal":"Frontiers in Neurology","n_participants":234,"pmid":"37360335","source_url":"https://pubmed.ncbi.nlm.nih.gov/37360335/","study_design":"longitudinal study","title":"Disparities in brain health comorbidity management in intracerebral hemorrhage","title_match":false,"year":2023},{"alzhub_score":46,"alzhub_url":"https://alzhub.org/study/frequency-of-unrecognized-and-undertreated-dementia-risk-factors-in-41433883","doi":"10.1002/alz70860_107565","journal":"Alzheimer s & Dementia","n_participants":105,"pmid":"41433883","source_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12725708/","study_design":"longitudinal study","title":"Frequency of Unrecognized and Undertreated Dementia Risk Factors in Community\u2010dwelling Latino and Black Americans","title_match":false,"year":2025},{"alzhub_score":44,"alzhub_url":"https://alzhub.org/study/hearing-impairment-hearing-aid-use-and-cognitive-outcomes-in-older-41433879","doi":"10.1002/alz70860_106643","journal":"Alzheimer s & Dementia","n_participants":179,"pmid":"41433879","source_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12725432/","study_design":"cross-sectional","title":"Hearing Impairment, Hearing Aid Use, and Cognitive Outcomes in Older Adults: A Cross\u2010Sectional Study","title_match":true,"year":2025},{"alzhub_score":47,"alzhub_url":"https://alzhub.org/study/arealevel-deprivation-is-associated-with-rate-of-memory-decline-in-ccce1fef","doi":"10.1002/alz.056608","journal":"Alzheimer s & Dementia","n_participants":2554,"pmid":null,"source_url":"https://doi.org/10.1002/alz.056608","study_design":"longitudinal study","title":"Area\u2010level deprivation is associated with rate of memory decline in late life within a community\u2010based cohort","title_match":false,"year":2021},{"alzhub_score":63,"alzhub_url":"https://alzhub.org/study/population-attributable-fraction-of-incident-dementia-associated-with-40244612","doi":"10.1001/jamaoto.2025.0192","journal":"JAMA Otolaryngology\u2013Head & Neck Surgery","n_participants":2946,"pmid":"40244612","source_url":"https://pubmed.ncbi.nlm.nih.gov/40244612/","study_design":"cohort study","title":"Population Attributable Fraction of Incident Dementia Associated With Hearing Loss","title_match":true,"year":2025},{"alzhub_score":51,"alzhub_url":"https://alzhub.org/study/hearing-loss-diet-and-cognitive-decline-interconnections-for-dementia-40015758","doi":"10.1016/j.tjpad.2024.100052","journal":"The Journal of Prevention of Alzheimer s Disease","n_participants":5145,"pmid":"40015758","source_url":"https://pubmed.ncbi.nlm.nih.gov/40015758/","study_design":"cohort study","title":"Hearing loss, diet, and cognitive decline: interconnections for dementia prevention","title_match":true,"year":2025},{"alzhub_score":48,"alzhub_url":"https://alzhub.org/study/hearing-impairment-and-dementia-cause-catalyst-or-consequence-40377748","doi":"10.1007/s00415-025-13140-x","journal":"Journal of Neurology","n_participants":null,"pmid":"40377748","source_url":"https://pubmed.ncbi.nlm.nih.gov/40377748/","study_design":null,"title":"Hearing impairment and dementia: cause, catalyst or consequence?","title_match":true,"year":2025},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/age-related-hearing-loss-and-dementia-risk-across-the-lifespan-40885376","doi":"10.1016/j.neuroscience.2025.08.056","journal":"Neuroscience","n_participants":null,"pmid":"40885376","source_url":"https://pubmed.ncbi.nlm.nih.gov/40885376/","study_design":null,"title":"Age-related hearing loss and dementia risk across the lifespan: mechanisms, equity, and prevention","title_match":true,"year":2025},{"alzhub_score":56,"alzhub_url":"https://alzhub.org/study/self-reported-hearing-aid-use-and-risk-of-incident-dementia-40824575","doi":"10.1001/jamaneurol.2025.2713","journal":"JAMA Neurology","n_participants":null,"pmid":"40824575","source_url":"https://pubmed.ncbi.nlm.nih.gov/40824575/","study_design":"cohort study","title":"Self-Reported Hearing Aid Use and Risk of Incident Dementia","title_match":true,"year":2025},{"alzhub_score":65,"alzhub_url":"https://alzhub.org/study/hearing-loss-brain-structure-cognition-and-dementia-risk-in-the-41191359","doi":"10.1001/jamanetworkopen.2025.39209","journal":"JAMA Network Open","n_participants":1656,"pmid":"41191359","source_url":"https://pubmed.ncbi.nlm.nih.gov/41191359/","study_design":"cohort study","title":"Hearing Loss, Brain Structure, Cognition, and Dementia Risk in the Framingham Heart Study","title_match":true,"year":2025},{"alzhub_score":42,"alzhub_url":"https://alzhub.org/study/dementia-and-hearing-loss-from-risk-to-mechanisms-and-management-41783253","doi":"10.3389/frdem.2026.1736003","journal":"Frontiers in Dementia","n_participants":null,"pmid":"41783253","source_url":"https://pubmed.ncbi.nlm.nih.gov/41783253/","study_design":null,"title":"Dementia and hearing loss: from risk to mechanisms and management","title_match":true,"year":2026},{"alzhub_score":53,"alzhub_url":"https://alzhub.org/study/treating-hearing-loss-with-hearing-aids-for-the-prevention-of-41534012","doi":"10.1212/wnl.0000000000214572","journal":"Neurology","n_participants":null,"pmid":"41534012","source_url":"https://pubmed.ncbi.nlm.nih.gov/41534012/","study_design":null,"title":"Treating Hearing Loss With Hearing Aids for the Prevention of Cognitive Decline and Dementia","title_match":true,"year":2026},{"alzhub_score":59,"alzhub_url":"https://alzhub.org/study/associations-of-modifiable-dementia-risk-factors-with-dementia-and-39882349","doi":"10.3389/fpubh.2025.1529969","journal":"Frontiers in Public Health","n_participants":30113,"pmid":"39882349","source_url":"https://pubmed.ncbi.nlm.nih.gov/39882349/","study_design":"longitudinal study","title":"Associations of modifiable dementia risk factors with dementia and cognitive decline: evidence from three prospective cohorts","title_match":false,"year":2025},{"alzhub_score":66,"alzhub_url":"https://alzhub.org/study/early-detection-and-management-of-hearing-loss-to-reduce-dementia-39835654","doi":"10.1093/ageing/afaf004","journal":"Age and Ageing","n_participants":58,"pmid":"39835654","source_url":"https://pubmed.ncbi.nlm.nih.gov/39835654/","study_design":"randomized controlled trial","title":"Early detection and management of hearing loss to reduce dementia risk in older adults with mild cognitive impairment: findings from the treating auditory impairment and cognition trial (TACT)","title_match":true,"year":2025},{"alzhub_score":52,"alzhub_url":"https://alzhub.org/study/from-hearing-aid-uptake-to-hearing-aid-effectiveness-rethinking-fcd1fddf","doi":"10.1002/sen2.70034","journal":"Sensory Neuroscience","n_participants":61089,"pmid":null,"source_url":"https://doi.org/10.1002/sen2.70034","study_design":"longitudinal study","title":"From Hearing Aid Uptake to Hearing Aid Effectiveness: Rethinking Dementia Risk Reduction in Adults With Hearing Loss","title_match":true,"year":2026},{"alzhub_score":68,"alzhub_url":"https://alzhub.org/study/hearing-loss-and-falls-40111358","doi":"10.1001/jamaoto.2025.0056","journal":"JAMA Otolaryngology\u2013Head & Neck Surgery","n_participants":935,"pmid":"40111358","source_url":"https://pubmed.ncbi.nlm.nih.gov/40111358/","study_design":"systematic review","title":"Hearing Loss and Falls","title_match":true,"year":2025},{"alzhub_score":58,"alzhub_url":"https://alzhub.org/study/cognitive-benefits-of-hearing-intervention-vary-by-risk-of-cognitive-40369891","doi":"10.1002/alz.70156","journal":"Alzheimer s & Dementia","n_participants":2692,"pmid":"40369891","source_url":"https://pubmed.ncbi.nlm.nih.gov/40369891/","study_design":null,"title":"Cognitive benefits of hearing intervention vary by risk of cognitive decline: A secondary analysis of the ACHIEVE trial","title_match":true,"year":2025},{"alzhub_score":57,"alzhub_url":"https://alzhub.org/study/language-literacy-and-sensory-impairments-and-missing-cognitive-test-40355654","doi":"10.1007/s40520-025-03039-y","journal":"Aging Clinical and Experimental Research","n_participants":9755,"pmid":"40355654","source_url":"https://pubmed.ncbi.nlm.nih.gov/40355654/","study_design":"longitudinal study","title":"Language, literacy, and sensory impairments and missing cognitive test scores in the Harmonized Cognitive Assessment Protocol of the China Health and Retirement Longitudinal Study","title_match":false,"year":2025},{"alzhub_score":46,"alzhub_url":"https://alzhub.org/study/reliability-and-validity-of-selfreported-risk-factors-for-stroke-and-40118792","doi":"10.1161/jaha.124.038730","journal":"Journal of the American Heart Association","n_participants":null,"pmid":"40118792","source_url":"https://pubmed.ncbi.nlm.nih.gov/40118792/","study_design":"cross-sectional","title":"Reliability and Validity of Self\u2010Reported Risk Factors for Stroke and Dementia","title_match":false,"year":2025},{"alzhub_score":54,"alzhub_url":"https://alzhub.org/study/hearing-and-cognitive-scores-measured-with-the-montreal-cognitive-39846386","doi":"10.1002/alz.14514","journal":"Alzheimer s & Dementia","n_participants":6879,"pmid":"39846386","source_url":"https://pubmed.ncbi.nlm.nih.gov/39846386/","study_design":"cohort study","title":"Hearing and cognitive scores measured with the Montreal Cognitive Assessment Scale in The HUNT Study, Norway","title_match":false,"year":2025},{"alzhub_score":42,"alzhub_url":"https://alzhub.org/study/decomposing-racial-and-ethnic-disparities-in-risk-and-protective-40673372","doi":"10.1080/07317115.2025.2534651","journal":"Clinical Gerontologist","n_participants":3495,"pmid":"40673372","source_url":"https://pubmed.ncbi.nlm.nih.gov/40673372/","study_design":null,"title":"Decomposing Racial and Ethnic Disparities in Risk and Protective Factors of Dementia in the U.S","title_match":false,"year":2025},{"alzhub_score":44,"alzhub_url":"https://alzhub.org/study/cognitive-assessment-in-hearing-aid-clinics-is-it-feasible-to-40233135","doi":"10.1177/00368504251335410","journal":"Science Progress","n_participants":null,"pmid":"40233135","source_url":"https://pubmed.ncbi.nlm.nih.gov/40233135/","study_design":"cohort study","title":"Cognitive assessment in hearing aid clinics: Is it feasible to implement in a National Health Service (NHS) setting?","title_match":true,"year":2025},{"alzhub_score":51,"alzhub_url":"https://alzhub.org/study/rural-urban-differences-in-modifiable-dementia-risk-factors-among-u-s-41209367","doi":"10.1177/25424823251395318","journal":"Journal of Alzheimer s Disease Reports","n_participants":16981,"pmid":"41209367","source_url":"https://pubmed.ncbi.nlm.nih.gov/41209367/","study_design":"cross-sectional","title":"Rural-urban differences in modifiable dementia risk factors among U.S. populations aged 45 years or older","title_match":false,"year":2025},{"alzhub_score":46,"alzhub_url":"https://alzhub.org/study/sensory-impairment-and-dementia-risk-among-older-adults-in-rural-40693440","doi":"10.1002/alz.70513","journal":"Alzheimer s & Dementia","n_participants":567,"pmid":"40693440","source_url":"https://pubmed.ncbi.nlm.nih.gov/40693440/","study_design":null,"title":"Sensory impairment and dementia risk among older adults in rural South Africa","title_match":false,"year":2025},{"alzhub_score":40,"alzhub_url":"https://alzhub.org/study/disparities-in-clinical-trial-participation-for-hearing-loss-40285653","doi":"10.1002/lary.32213","journal":"The Laryngoscope","n_participants":null,"pmid":"40285653","source_url":"https://pubmed.ncbi.nlm.nih.gov/40285653/","study_design":null,"title":"Disparities in Clinical Trial Participation for Hearing Loss Treatment and Cognitive Outcomes in the United States: A Scoping Review","title_match":true,"year":2025},{"alzhub_score":39,"alzhub_url":"https://alzhub.org/study/cochlear-implantation-is-associated-with-reduced-incidence-of-40200399","doi":"10.1097/aud.0000000000001660","journal":"Ear and Hearing","n_participants":649,"pmid":"40200399","source_url":"https://pubmed.ncbi.nlm.nih.gov/40200399/","study_design":null,"title":"Cochlear Implantation Is Associated With Reduced Incidence of Dementia in Severe Hearing Loss","title_match":true,"year":2025},{"alzhub_score":43,"alzhub_url":"https://alzhub.org/study/prevalence-of-hearing-loss-in-patients-with-dementia-and-its-40297793","doi":"10.1177/20503121251333033","journal":"SAGE Open Medicine","n_participants":88,"pmid":"40297793","source_url":"https://pubmed.ncbi.nlm.nih.gov/40297793/","study_design":"cross-sectional","title":"Prevalence of hearing loss in patients with dementia and its association with dementia severity","title_match":true,"year":2025},{"alzhub_score":53,"alzhub_url":"https://alzhub.org/study/prevalence-and-risk-factors-of-mild-cognitive-impairment-and-dementia-40469616","doi":"10.3389/fpubh.2025.1567073","journal":"Frontiers in Public Health","n_participants":385,"pmid":"40469616","source_url":"https://pubmed.ncbi.nlm.nih.gov/40469616/","study_design":"cross-sectional","title":"Prevalence and risk factors of mild cognitive impairment and dementia in northern Peru","title_match":false,"year":2025},{"alzhub_score":61,"alzhub_url":"https://alzhub.org/study/moving-beyond-the-prevalent-exposure-design-for-causal-inference-in-39894022","doi":"10.1016/j.lanhl.2024.100675","journal":"The Lancet Healthy Longevity","n_participants":null,"pmid":"39894022","source_url":"https://pubmed.ncbi.nlm.nih.gov/39894022/","study_design":"cohort study","title":"Moving beyond the prevalent exposure design for causal inference in dementia research","title_match":false,"year":2025},{"alzhub_score":59,"alzhub_url":"https://alzhub.org/study/timing-of-risk-factors-prodromal-features-and-comorbidities-of-39819557","doi":"10.1186/s13195-024-01662-x","journal":"Alzheimer s Research & Therapy","n_participants":1686759,"pmid":"39819557","source_url":"https://pubmed.ncbi.nlm.nih.gov/39819557/","study_design":"cohort study","title":"Timing of risk factors, prodromal features, and comorbidities of dementia from a large health claims case\u2013control study","title_match":false,"year":2025},{"alzhub_score":43,"alzhub_url":"https://alzhub.org/study/the-potential-for-dementia-prevention-in-japan-a-population-41647885","doi":"10.1016/j.lanwpc.2025.101792","journal":"The Lancet Regional Health - Western Pacific","n_participants":null,"pmid":"41647885","source_url":"https://pubmed.ncbi.nlm.nih.gov/41647885/","study_design":null,"title":"The potential for dementia prevention in Japan: a population attributable fraction calculation for 14 modifiable risk factors and estimates of the impact of risk factor reductions","title_match":false,"year":2026},{"alzhub_score":47,"alzhub_url":"https://alzhub.org/study/sex-and-socioeconomic-differences-in-15-year-prevalence-trends-for-40425022","doi":"10.1016/j.lanhl.2025.100711","journal":"The Lancet Healthy Longevity","n_participants":null,"pmid":"40425022","source_url":"https://pubmed.ncbi.nlm.nih.gov/40425022/","study_design":"cross-sectional","title":"Sex and socioeconomic differences in 15-year prevalence trends for modifiable dementia risk factors in Australia: a cross-sectional, time series analysis","title_match":false,"year":2025},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/dissecting-the-interactions-of-diabetes-mellitus-and-hearing-loss-40722262","doi":"10.3390/brainsci15070669","journal":"Brain Sciences","n_participants":null,"pmid":"40722262","source_url":"https://pubmed.ncbi.nlm.nih.gov/40722262/","study_design":null,"title":"Dissecting the Interactions of Diabetes Mellitus and Hearing Loss with Cognitive Decline and Dementia","title_match":true,"year":2025},{"alzhub_score":54,"alzhub_url":"https://alzhub.org/study/sex-differences-in-modifiable-risk-factors-of-dementia-and-their-42157293","doi":"10.1186/s13293-026-00908-7","journal":"Biology of Sex Differences","n_participants":17182,"pmid":"42157293","source_url":"https://pubmed.ncbi.nlm.nih.gov/42157293/","study_design":"cohort study","title":"Sex differences in modifiable risk factors of dementia and their associations with cognition","title_match":false,"year":2026},{"alzhub_score":50,"alzhub_url":"https://alzhub.org/study/life-course-modifiable-risk-factors-of-dementia-replicating-the-2024-41434761","doi":"10.1002/alz70860_107692","journal":"Alzheimer s & Dementia","n_participants":5526,"pmid":"41434761","source_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12726475/","study_design":"cross-sectional","title":"Life Course Modifiable Risk Factors of Dementia: Replicating the 2024 Lancet Commission Model in a Single Longitudinal Cohort","title_match":false,"year":2025},{"alzhub_score":40,"alzhub_url":"https://alzhub.org/study/blood-neurofilament-light-chain-and-phospho-tau-181-in-subjects-with-39941343","doi":"10.3390/jcm14030672","journal":"Journal of Clinical Medicine","n_participants":30,"pmid":"39941343","source_url":"https://pubmed.ncbi.nlm.nih.gov/39941343/","study_design":null,"title":"Blood Neurofilament Light Chain and Phospho-Tau 181 in Subjects with Mild Cognitive Impairment Due to Age-Related Hearing Loss","title_match":true,"year":2025},{"alzhub_score":48,"alzhub_url":"https://alzhub.org/study/association-of-hearing-loss-to-brain-structure-and-cognition-in-the-41434410","doi":"10.1002/alz70860_101741","journal":"Alzheimer s & Dementia","n_participants":1656,"pmid":"41434410","source_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12726679/","study_design":null,"title":"Association of hearing loss to brain structure and cognition in the Framingham Heart Study","title_match":true,"year":2025},{"alzhub_score":58,"alzhub_url":"https://alzhub.org/study/parkinsons-disease-dementia-and-hearing-impairment-are-they-related-a-41954638","doi":"10.1007/s00221-026-07282-1","journal":"Experimental Brain Research","n_participants":158686,"pmid":"41954638","source_url":"https://pubmed.ncbi.nlm.nih.gov/41954638/","study_design":"cohort study","title":"Parkinson\u2019s disease dementia and hearing impairment, are they related? A UK biobank pilot analysis","title_match":true,"year":2026},{"alzhub_score":53,"alzhub_url":"https://alzhub.org/study/mediators-of-educational-differences-in-dementia-risk-later-in-life-40211155","doi":"10.1186/s12889-025-22592-9","journal":"BMC Public Health","n_participants":7655,"pmid":"40211155","source_url":"https://pubmed.ncbi.nlm.nih.gov/40211155/","study_design":null,"title":"Mediators of educational differences in dementia risk later in life: evidence from the HUNT study","title_match":false,"year":2025},{"alzhub_score":51,"alzhub_url":"https://alzhub.org/study/identifying-the-optimal-combinations-of-modifiable-dementia-risk-40817010","doi":"10.1016/j.tjpad.2025.100321","journal":"The Journal of Prevention of Alzheimer s Disease","n_participants":30097,"pmid":"40817010","source_url":"https://pubmed.ncbi.nlm.nih.gov/40817010/","study_design":"longitudinal study","title":"Identifying the optimal combinations of modifiable dementia risk factors to target in multidomain intervention \u2013 Three-year longitudinal findings from the Canadian longitudinal study on aging","title_match":false,"year":2025},{"alzhub_score":38,"alzhub_url":"https://alzhub.org/study/prevention-of-cognitive-impairment-and-dementia-in-people-with-41032653","doi":"10.1177/1877718x251365769","journal":"Journal of Parkinson s Disease","n_participants":null,"pmid":"41032653","source_url":"https://pubmed.ncbi.nlm.nih.gov/41032653/","study_design":null,"title":"Prevention of cognitive impairment and dementia in people with Parkinson's disease: A call-to-action","title_match":false,"year":2025},{"alzhub_score":44,"alzhub_url":"https://alzhub.org/study/hearing-and-listening-experience-helix-evaluation-of-a-co-designed-39972554","doi":"10.1177/17470218251324168","journal":"Quarterly Journal of Experimental Psychology","n_participants":43,"pmid":"39972554","source_url":"https://pubmed.ncbi.nlm.nih.gov/39972554/","study_design":null,"title":"HEaring and LIstening eXperience (HELIX): Evaluation of a co-designed serious game for auditory-cognitive training","title_match":false,"year":2025},{"alzhub_score":48,"alzhub_url":"https://alzhub.org/study/impact-of-implantable-hearing-devices-on-delirium-risk-in-patients-40059784","doi":"10.1097/mao.0000000000004416","journal":"Otology & Neurotology","n_participants":36,"pmid":"40059784","source_url":"https://pubmed.ncbi.nlm.nih.gov/40059784/","study_design":"retrospective cohort","title":"Impact of Implantable Hearing Devices on Delirium Risk in Patients with Hearing Loss: A National Database Study","title_match":true,"year":2025},{"alzhub_score":16,"alzhub_url":"https://alzhub.org/study/patterns-of-modifiable-lifestyle-behavioural-and-health-related-risk-bf9e6ff5","doi":"10.64898/2026.09.24.26363838","journal":"medRxiv (preprint)","n_participants":151832,"pmid":null,"source_url":"https://doi.org/10.64898/2026.09.24.26363838","study_design":null,"title":"Patterns of modifiable lifestyle, behavioural and health-related risk factors and their associations with incident dementia in UK Biobank","title_match":false,"year":2026},{"alzhub_score":16,"alzhub_url":"https://alzhub.org/study/public-awareness-of-the-hearing-loss-dementia-link-and-self-reported-bec3301c","doi":"10.64898/2026.01.12.26343953","journal":"medRxiv (preprint)","n_participants":null,"pmid":null,"source_url":"https://doi.org/10.64898/2026.01.12.26343953","study_design":"cross-sectional","title":"Public awareness of the hearing loss-dementia link and self-reported behavioral changes in middle- to older-aged Canadians","title_match":true,"year":2026},{"alzhub_score":51,"alzhub_url":"https://alzhub.org/study/diversity-in-united-states-dementia-prevention-trials-an-updated-39947158","doi":"10.1159/000543905","journal":"Dementia and geriatric cognitive disorders","n_participants":null,"pmid":"39947158","source_url":"https://pubmed.ncbi.nlm.nih.gov/39947158/","study_design":"systematic review","title":"Diversity in United States Dementia Prevention Trials: An Updated Systematic Review of Eligibility Criteria and Recruitment Strategies","title_match":false,"year":2025},{"alzhub_score":55,"alzhub_url":"https://alzhub.org/study/patient-characteristics-associated-with-being-offered-or-choosing-36988958","doi":"10.1001/jamanetworkopen.2023.5242","journal":"JAMA network open","n_participants":1593,"pmid":"36988958","source_url":"https://pubmed.ncbi.nlm.nih.gov/36988958/","study_design":null,"title":"Patient Characteristics Associated With Being Offered or Choosing Telephone vs Video Virtual Visits Among Medicare Beneficiaries","title_match":false,"year":2023},{"alzhub_score":57,"alzhub_url":"https://alzhub.org/study/hearing-loss-and-cognitive-decline-in-older-adults-23337978","doi":"10.1001/jamainternmed.2013.1868","journal":"JAMA Internal Medicine","n_participants":1984,"pmid":"23337978","source_url":"https://pubmed.ncbi.nlm.nih.gov/23337978/","study_design":null,"title":"Hearing Loss and Cognitive Decline in Older Adults","title_match":true,"year":2013},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/immediate-improvement-of-speech-in-noise-perception-through-31006700","doi":"10.3233/rnn-190898","journal":"Restorative neurology and neuroscience","n_participants":null,"pmid":"31006700","source_url":"https://pubmed.ncbi.nlm.nih.gov/31006700/","study_design":null,"title":"Immediate improvement of speech-in-noise perception through multisensory stimulation via an auditory to tactile sensory substitution","title_match":false,"year":2019},{"alzhub_score":40,"alzhub_url":"https://alzhub.org/study/maternally-inherited-mitochondrial-myopathy-and-myoclonic-epilepsy-3922281","doi":"10.1002/ana.410170303","journal":"Annals of neurology","n_participants":null,"pmid":"3922281","source_url":"https://pubmed.ncbi.nlm.nih.gov/3922281/","study_design":null,"title":"Maternally inherited mitochondrial myopathy and myoclonic epilepsy","title_match":false,"year":1985},{"alzhub_score":72,"alzhub_url":"https://alzhub.org/study/reduced-mortality-in-treating-acutely-sick-frail-older-patients-in-a-12028163","doi":"10.1046/j.1532-5415.2002.50202.x","journal":"Journal of the American Geriatrics Society","n_participants":127,"pmid":"12028163","source_url":"https://pubmed.ncbi.nlm.nih.gov/12028163/","study_design":"randomized controlled trial","title":"Reduced mortality in treating acutely sick, frail older patients in a geriatric evaluation and management unit. A prospective randomized trial","title_match":false,"year":2002},{"alzhub_score":69,"alzhub_url":"https://alzhub.org/study/can-hearing-aids-delay-time-to-diagnosis-of-dementia-depression-or-31486068","doi":"10.1111/jgs.16109","journal":"Journal of the American Geriatrics Society","n_participants":114,"pmid":"31486068","source_url":"https://pubmed.ncbi.nlm.nih.gov/31486068/","study_design":"cohort study","title":"Can Hearing Aids Delay Time to Diagnosis of Dementia, Depression, or Falls in Older Adults?","title_match":true,"year":2019},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/selecting-target-conditions-for-quality-of-care-improvement-in-10798460","doi":"10.1111/j.1532-5415.2000.tb04691.x","journal":"Journal of the American Geriatrics Society","n_participants":null,"pmid":"10798460","source_url":"https://pubmed.ncbi.nlm.nih.gov/10798460/","study_design":null,"title":"Selecting target conditions for quality of care improvement in vulnerable older adults","title_match":false,"year":2000},{"alzhub_score":48,"alzhub_url":"https://alzhub.org/study/association-of-sensory-and-cognitive-impairment-with-healthcare-30924932","doi":"10.1111/jgs.15891","journal":"Journal of the American Geriatrics Society","n_participants":24,"pmid":"30924932","source_url":"https://pubmed.ncbi.nlm.nih.gov/30924932/","study_design":null,"title":"Association of Sensory and Cognitive Impairment With Healthcare Utilization and Cost in Older Adults","title_match":false,"year":2019},{"alzhub_score":45,"alzhub_url":"https://alzhub.org/study/age-related-hearing-loss-and-dementia-31335455","doi":"10.1097/wad.0000000000000325","journal":"Alzheimer disease and associated disorders","n_participants":null,"pmid":"31335455","source_url":"https://pubmed.ncbi.nlm.nih.gov/31335455/","study_design":null,"title":"Age-related Hearing Loss and Dementia","title_match":true,"year":2019},{"alzhub_score":52,"alzhub_url":"https://alzhub.org/study/central-auditory-dysfunction-as-a-harbinger-of-alzheimer-dementia-21502479","doi":"10.1001/archoto.2011.28","journal":"Archives of otolaryngology--head & neck surgery","n_participants":null,"pmid":"21502479","source_url":"https://pubmed.ncbi.nlm.nih.gov/21502479/","study_design":"cohort study","title":"Central auditory dysfunction as a harbinger of Alzheimer dementia","title_match":false,"year":2011},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/clinical-practice-guideline-age-related-hearing-loss-38687845","doi":"10.1002/ohn.750","journal":"Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery","n_participants":null,"pmid":"38687845","source_url":"https://pubmed.ncbi.nlm.nih.gov/38687845/","study_design":null,"title":"Clinical Practice Guideline: Age-Related Hearing Loss","title_match":true,"year":2024},{"alzhub_score":43,"alzhub_url":"https://alzhub.org/study/mutations-in-dnmt1-cause-hereditary-sensory-neuropathy-with-dementia-21532572","doi":"10.1038/ng.830","journal":"Nature genetics","n_participants":null,"pmid":"21532572","source_url":"https://pubmed.ncbi.nlm.nih.gov/21532572/","study_design":null,"title":"Mutations in DNMT1 cause hereditary sensory neuropathy with dementia and hearing loss","title_match":true,"year":2011},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/excitotoxicity-bridge-to-various-triggers-in-neurodegenerative-23123057","doi":"10.1016/j.ejphar.2012.10.032","journal":"European journal of pharmacology","n_participants":null,"pmid":"23123057","source_url":"https://pubmed.ncbi.nlm.nih.gov/23123057/","study_design":null,"title":"Excitotoxicity: bridge to various triggers in neurodegenerative disorders","title_match":false,"year":2013},{"alzhub_score":55,"alzhub_url":"https://alzhub.org/study/relationship-of-hearing-impairment-to-dementia-and-cognitive-2926927","doi":"10.1001/jama.1989.03420130084028","journal":"JAMA","n_participants":null,"pmid":"2926927","source_url":"https://pubmed.ncbi.nlm.nih.gov/2926927/","study_design":"case-control study","title":"Relationship of hearing impairment to dementia and cognitive dysfunction in older adults","title_match":true,"year":1989},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/glutamate-in-cns-disorders-as-a-target-for-drug-development-an-update-15616669","doi":"10.1358/dnp.1998.11.9.863689","journal":"Drug news & perspectives","n_participants":null,"pmid":"15616669","source_url":"https://pubmed.ncbi.nlm.nih.gov/15616669/","study_design":null,"title":"Glutamate in CNS disorders as a target for drug development: an update","title_match":false,"year":1998},{"alzhub_score":38,"alzhub_url":"https://alzhub.org/study/causes-of-hyperhomocysteinemia-and-its-pathological-significance-29552692","doi":"10.1007/s12272-018-1016-4","journal":"Archives of pharmacal research","n_participants":null,"pmid":"29552692","source_url":"https://pubmed.ncbi.nlm.nih.gov/29552692/","study_design":null,"title":"Causes of hyperhomocysteinemia and its pathological significance","title_match":false,"year":2018},{"alzhub_score":52,"alzhub_url":"https://alzhub.org/study/validation-of-a-26-point-telephone-version-of-the-mini-mental-state-15157348","doi":"10.1177/0891988704264534","journal":"Journal of geriatric psychiatry and neurology","n_participants":null,"pmid":"15157348","source_url":"https://pubmed.ncbi.nlm.nih.gov/15157348/","study_design":"longitudinal study","title":"Validation of a 26-point telephone version of the Mini-Mental State Examination","title_match":false,"year":2004},{"alzhub_score":53,"alzhub_url":"https://alzhub.org/study/chronic-inflammation-inflammaging-in-the-ageing-cochlea-a-novel-29017893","doi":"10.1016/j.arr.2017.10.002","journal":"Ageing research reviews","n_participants":null,"pmid":"29017893","source_url":"https://pubmed.ncbi.nlm.nih.gov/29017893/","study_design":"cohort study","title":"Chronic inflammation - inflammaging - in the ageing cochlea: A novel target for future presbycusis therapy","title_match":true,"year":2017},{"alzhub_score":64,"alzhub_url":"https://alzhub.org/study/longitudinal-relationship-between-hearing-aid-use-and-cognitive-29637544","doi":"10.1111/jgs.15363","journal":"Journal of the American Geriatrics Society","n_participants":2040,"pmid":"29637544","source_url":"https://pubmed.ncbi.nlm.nih.gov/29637544/","study_design":"cohort study","title":"Longitudinal Relationship Between Hearing Aid Use and Cognitive Function in Older Americans","title_match":true,"year":2018},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/using-resting-state-functional-connectivity-to-unravel-networks-of-23895873","doi":"10.1016/j.heares.2013.07.010","journal":"Hearing research","n_participants":null,"pmid":"23895873","source_url":"https://pubmed.ncbi.nlm.nih.gov/23895873/","study_design":null,"title":"Using resting state functional connectivity to unravel networks of tinnitus","title_match":false,"year":2014},{"alzhub_score":40,"alzhub_url":"https://alzhub.org/study/essential-tremor-neurodegenerative-or-nondegenerative-disease-towards-19750493","doi":"10.1002/mds.22755","journal":"Movement disorders : official journal of the Movement Disorder Society","n_participants":null,"pmid":"19750493","source_url":"https://pubmed.ncbi.nlm.nih.gov/19750493/","study_design":null,"title":"Essential tremor--neurodegenerative or nondegenerative disease towards a working definition of ET","title_match":false,"year":2009},{"alzhub_score":47,"alzhub_url":"https://alzhub.org/study/hearing-and-dementia-from-ears-to-brain-33351095","doi":"10.1093/brain/awaa429","journal":"Brain : a journal of neurology","n_participants":null,"pmid":"33351095","source_url":"https://pubmed.ncbi.nlm.nih.gov/33351095/","study_design":null,"title":"Hearing and dementia: from ears to brain","title_match":false,"year":2021},{"alzhub_score":43,"alzhub_url":"https://alzhub.org/study/oxidative-stress-and-4-hydroxy-2-nonenal-4-hne-implications-in-the-35411309","doi":"10.1155/2022/2233906","journal":"Journal of immunology research","n_participants":null,"pmid":"35411309","source_url":"https://pubmed.ncbi.nlm.nih.gov/35411309/","study_design":null,"title":"Oxidative Stress and 4-hydroxy-2-nonenal (4-HNE): Implications in the Pathogenesis and Treatment of Aging-related Diseases","title_match":false,"year":2022},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/impact-of-aging-on-the-auditory-system-and-related-cognitive-29556173","doi":"10.3389/fnins.2018.00125","journal":"Frontiers in neuroscience","n_participants":null,"pmid":"29556173","source_url":"https://pubmed.ncbi.nlm.nih.gov/29556173/","study_design":"narrative review","title":"Impact of Aging on the Auditory System and Related Cognitive Functions: A Narrative Review","title_match":false,"year":2018},{"alzhub_score":40,"alzhub_url":"https://alzhub.org/study/a-review-of-new-insights-on-the-association-between-hearing-loss-and-27214827","doi":"10.14639/0392-100x-993","journal":"Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale","n_participants":null,"pmid":"27214827","source_url":"https://pubmed.ncbi.nlm.nih.gov/27214827/","study_design":null,"title":"A review of new insights on the association between hearing loss and cognitive decline in ageing","title_match":true,"year":2016},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/nitrones-as-therapeutics-18793715","doi":"10.1016/j.freeradbiomed.2008.08.017","journal":"Free radical biology & medicine","n_participants":null,"pmid":"18793715","source_url":"https://pubmed.ncbi.nlm.nih.gov/18793715/","study_design":null,"title":"Nitrones as therapeutics","title_match":false,"year":2008},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/using-virtual-reality-in-medical-education-to-teach-empathy-30271295","doi":"10.5195/jmla.2018.518","journal":"Journal of the Medical Library Association : JMLA","n_participants":null,"pmid":"30271295","source_url":"https://pubmed.ncbi.nlm.nih.gov/30271295/","study_design":null,"title":"Using virtual reality in medical education to teach empathy","title_match":false,"year":2018},{"alzhub_score":48,"alzhub_url":"https://alzhub.org/study/hearing-impairment-and-mental-state-in-the-elderly-living-at-home-7427503","doi":"10.1136/bmj.281.6245.903","journal":"British medical journal","n_participants":253,"pmid":"7427503","source_url":"https://pubmed.ncbi.nlm.nih.gov/7427503/","study_design":null,"title":"Hearing impairment and mental state in the elderly living at home","title_match":true,"year":1980},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/susac-s-syndrome-1975-2005-microangiopathy-autoimmune-endotheliopathy-17331544","doi":"10.1016/j.jns.2007.01.036","journal":"Journal of the neurological sciences","n_participants":null,"pmid":"17331544","source_url":"https://pubmed.ncbi.nlm.nih.gov/17331544/","study_design":null,"title":"Susac's syndrome: 1975-2005 microangiopathy/autoimmune endotheliopathy","title_match":false,"year":2007},{"alzhub_score":66,"alzhub_url":"https://alzhub.org/study/unilateral-cochlear-implants-for-severe-profound-or-moderate-sloping-32857157","doi":"10.1001/jamaoto.2020.0998","journal":"JAMA otolaryngology-- head & neck surgery","n_participants":null,"pmid":"32857157","source_url":"https://pubmed.ncbi.nlm.nih.gov/32857157/","study_design":"systematic review","title":"Unilateral Cochlear Implants for Severe, Profound, or Moderate Sloping to Profound Bilateral Sensorineural Hearing Loss: A Systematic Review and Consensus Statements","title_match":true,"year":2020},{"alzhub_score":52,"alzhub_url":"https://alzhub.org/study/association-of-cognition-and-age-related-hearing-impairment-in-the-30193368","doi":"10.1001/jamaoto.2018.1656","journal":"JAMA otolaryngology-- head & neck surgery","n_participants":null,"pmid":"30193368","source_url":"https://pubmed.ncbi.nlm.nih.gov/30193368/","study_design":"cross-sectional","title":"Association of Cognition and Age-Related Hearing Impairment in the English Longitudinal Study of Ageing","title_match":true,"year":2018},{"alzhub_score":43,"alzhub_url":"https://alzhub.org/study/hearing-loss-and-cognition-what-we-know-and-where-we-need-to-go-35295208","doi":"10.3389/fnagi.2021.769405","journal":"Frontiers in aging neuroscience","n_participants":null,"pmid":"35295208","source_url":"https://pubmed.ncbi.nlm.nih.gov/35295208/","study_design":null,"title":"Hearing Loss and Cognition: What We Know and Where We Need to Go","title_match":true,"year":2021},{"alzhub_score":72,"alzhub_url":"https://alzhub.org/study/hearing-impairment-and-incident-dementia-findings-from-the-english-28734053","doi":"10.1111/jgs.14986","journal":"Journal of the American Geriatrics Society","n_participants":7865,"pmid":"28734053","source_url":"https://pubmed.ncbi.nlm.nih.gov/28734053/","study_design":"cohort study","title":"Hearing Impairment and Incident Dementia: Findings from the English Longitudinal Study of Ageing","title_match":true,"year":2017},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/autosomal-dominant-syndrome-with-strokelike-episodes-and-1926242","doi":"10.1161/01.str.22.10.1297","journal":"Stroke","n_participants":null,"pmid":"1926242","source_url":"https://pubmed.ncbi.nlm.nih.gov/1926242/","study_design":null,"title":"Autosomal dominant syndrome with strokelike episodes and leukoencephalopathy","title_match":false,"year":1991},{"alzhub_score":50,"alzhub_url":"https://alzhub.org/study/association-of-hearing-impairment-and-mortality-in-older-adults-25024235","doi":"10.1093/gerona/glu094","journal":"The journals of gerontology. Series A, Biological sciences and medical sciences","n_participants":1958,"pmid":"25024235","source_url":"https://pubmed.ncbi.nlm.nih.gov/25024235/","study_design":null,"title":"Association of hearing impairment and mortality in older adults","title_match":true,"year":2015},{"alzhub_score":74,"alzhub_url":"https://alzhub.org/study/olfactory-identification-deficits-and-increased-mortality-in-the-26031760","doi":"10.1002/ana.24447","journal":"Annals of neurology","n_participants":null,"pmid":"26031760","source_url":"https://pubmed.ncbi.nlm.nih.gov/26031760/","study_design":null,"title":"Olfactory identification deficits and increased mortality in the community","title_match":false,"year":2015},{"alzhub_score":48,"alzhub_url":"https://alzhub.org/study/death-depression-disability-and-dementia-associated-with-self-29304204","doi":"10.1093/gerona/glx250","journal":"The journals of gerontology. Series A, Biological sciences and medical sciences","n_participants":3777,"pmid":"29304204","source_url":"https://pubmed.ncbi.nlm.nih.gov/29304204/","study_design":null,"title":"Death, Depression, Disability, and Dementia Associated With Self-reported Hearing Problems: A 25-Year Study","title_match":false,"year":2018},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/susac-s-syndrome-update-20855088","doi":"10.1016/j.jns.2010.08.032","journal":"Journal of the neurological sciences","n_participants":null,"pmid":"20855088","source_url":"https://pubmed.ncbi.nlm.nih.gov/20855088/","study_design":null,"title":"Susac's Syndrome--update","title_match":false,"year":2010},{"alzhub_score":67,"alzhub_url":"https://alzhub.org/study/telemedicine-and-dementia-care-a-systematic-review-of-barriers-and-33887231","doi":"10.1016/j.jamda.2021.03.015","journal":"Journal of the American Medical Directors Association","n_participants":null,"pmid":"33887231","source_url":"https://pubmed.ncbi.nlm.nih.gov/33887231/","study_design":"systematic review","title":"Telemedicine and Dementia Care: A Systematic Review of Barriers and Facilitators","title_match":false,"year":2021},{"alzhub_score":67,"alzhub_url":"https://alzhub.org/study/tooth-loss-and-dementia-a-critical-examination-32942945","doi":"10.1177/0022034520957233","journal":"Journal of dental research","n_participants":null,"pmid":"32942945","source_url":"https://pubmed.ncbi.nlm.nih.gov/32942945/","study_design":"systematic review","title":"Tooth Loss and Dementia: A Critical Examination","title_match":false,"year":2021},{"alzhub_score":64,"alzhub_url":"https://alzhub.org/study/observed-hearing-loss-and-incident-dementia-in-a-multiethnic-cohort-28323321","doi":"10.1111/jgs.14848","journal":"Journal of the American Geriatrics Society","n_participants":1881,"pmid":"28323321","source_url":"https://pubmed.ncbi.nlm.nih.gov/28323321/","study_design":"cohort study","title":"Observed Hearing Loss and Incident Dementia in a Multiethnic Cohort","title_match":true,"year":2017},{"alzhub_score":50,"alzhub_url":"https://alzhub.org/study/visual-impairment-and-cognitive-dysfunction-in-alzheimer-s-disease-2023019","doi":"10.1007/bf02598307","journal":"Journal of general internal medicine","n_participants":null,"pmid":"2023019","source_url":"https://pubmed.ncbi.nlm.nih.gov/2023019/","study_design":"case-control study","title":"Visual impairment and cognitive dysfunction in Alzheimer's disease","title_match":false,"year":1991},{"alzhub_score":40,"alzhub_url":"https://alzhub.org/study/hearing-and-dementia-27372450","doi":"10.1007/s00415-016-8208-y","journal":"Journal of neurology","n_participants":null,"pmid":"27372450","source_url":"https://pubmed.ncbi.nlm.nih.gov/27372450/","study_design":null,"title":"Hearing and dementia","title_match":false,"year":2016},{"alzhub_score":40,"alzhub_url":"https://alzhub.org/study/noise-induced-hearing-loss-impairs-spatial-learning-memory-and-26842803","doi":"10.1038/srep20374","journal":"Scientific reports","n_participants":null,"pmid":"26842803","source_url":"https://pubmed.ncbi.nlm.nih.gov/26842803/","study_design":null,"title":"Noise induced hearing loss impairs spatial learning/memory and hippocampal neurogenesis in mice","title_match":true,"year":2016},{"alzhub_score":52,"alzhub_url":"https://alzhub.org/study/prevalence-and-incidence-of-health-problems-in-people-with-9089458","doi":"10.1111/j.1365-2788.1997.tb00675.x","journal":"Journal of intellectual disability research : JIDR","n_participants":null,"pmid":"9089458","source_url":"https://pubmed.ncbi.nlm.nih.gov/9089458/","study_design":"cohort study","title":"Prevalence and incidence of health problems in people with intellectual disability","title_match":false,"year":1997},{"alzhub_score":67,"alzhub_url":"https://alzhub.org/study/modifiable-risk-factors-for-incident-dementia-and-cognitive-35863541","doi":"10.1016/j.jad.2022.07.008","journal":"Journal of affective disorders","n_participants":null,"pmid":"35863541","source_url":"https://pubmed.ncbi.nlm.nih.gov/35863541/","study_design":"meta-analysis","title":"Modifiable risk factors for incident dementia and cognitive impairment: An umbrella review of evidence","title_match":false,"year":2022},{"alzhub_score":52,"alzhub_url":"https://alzhub.org/study/hearing-loss-is-negatively-related-to-episodic-and-semantic-long-term-20884779","doi":"10.1044/1092-4388(2010/09-0088)","journal":"Journal of speech, language, and hearing research : JSLHR","n_participants":null,"pmid":"20884779","source_url":"https://pubmed.ncbi.nlm.nih.gov/20884779/","study_design":"prospective cohort","title":"Hearing loss is negatively related to episodic and semantic long-term memory but not to short-term memory","title_match":true,"year":2011},{"alzhub_score":48,"alzhub_url":"https://alzhub.org/study/the-prevalence-of-peripheral-and-central-hearing-impairment-and-its-25733360","doi":"10.1159/000371597","journal":"Audiology & neuro-otology","n_participants":488,"pmid":"25733360","source_url":"https://pubmed.ncbi.nlm.nih.gov/25733360/","study_design":null,"title":"The prevalence of peripheral and central hearing impairment and its relation to cognition in older adults","title_match":true,"year":2014},{"alzhub_score":48,"alzhub_url":"https://alzhub.org/study/screening-of-chchd10-in-a-french-cohort-confirms-the-involvement-of-25155093","doi":"10.1016/j.neurobiolaging.2014.07.022","journal":"Neurobiology of aging","n_participants":115,"pmid":"25155093","source_url":"https://pubmed.ncbi.nlm.nih.gov/25155093/","study_design":null,"title":"Screening of CHCHD10 in a French cohort confirms the involvement of this gene in frontotemporal dementia with amyotrophic lateral sclerosis patients","title_match":false,"year":2014},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/elderly-onset-essential-tremor-and-mild-cognitive-impairment-a-21304183","doi":"10.3233/jad-2011-101572","journal":"Journal of Alzheimer's disease : JAD","n_participants":null,"pmid":"21304183","source_url":"https://pubmed.ncbi.nlm.nih.gov/21304183/","study_design":null,"title":"Elderly-onset essential tremor and mild cognitive impairment: a population-based study (NEDICES)","title_match":false,"year":2011},{"alzhub_score":74,"alzhub_url":"https://alzhub.org/study/widening-the-spectrum-of-risk-factors-comorbidities-and-prodromal-36342675","doi":"10.1001/jamaneurol.2022.3902","journal":"JAMA neurology","n_participants":345,"pmid":"36342675","source_url":"https://pubmed.ncbi.nlm.nih.gov/36342675/","study_design":"cohort study","title":"Widening the Spectrum of Risk Factors, Comorbidities, and Prodromal Features of Parkinson Disease","title_match":false,"year":2023},{"alzhub_score":76,"alzhub_url":"https://alzhub.org/study/prevalence-of-concurrent-functional-vision-and-hearing-impairment-and-33739429","doi":"10.1001/jamanetworkopen.2021.1558","journal":"JAMA network open","n_participants":7562,"pmid":"33739429","source_url":"https://pubmed.ncbi.nlm.nih.gov/33739429/","study_design":"cohort study","title":"Prevalence of Concurrent Functional Vision and Hearing Impairment and Association With Dementia in Community-Dwelling Medicare Beneficiaries","title_match":true,"year":2021},{"alzhub_score":38,"alzhub_url":"https://alzhub.org/study/motor-function-deficits-in-the-12-month-old-female-5xfad-mouse-model-28890389","doi":"10.1016/j.bbr.2017.09.009","journal":"Behavioural brain research","n_participants":null,"pmid":"28890389","source_url":"https://pubmed.ncbi.nlm.nih.gov/28890389/","study_design":null,"title":"Motor function deficits in the 12 month-old female 5xFAD mouse model of Alzheimer's disease","title_match":false,"year":2018},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/essential-tremor-beyond-the-motor-features-22217558","doi":"10.1016/j.parkreldis.2011.12.003","journal":"Parkinsonism & related disorders","n_participants":null,"pmid":"22217558","source_url":"https://pubmed.ncbi.nlm.nih.gov/22217558/","study_design":null,"title":"Essential tremor: beyond the motor features","title_match":false,"year":2012},{"alzhub_score":55,"alzhub_url":"https://alzhub.org/study/sensorial-frailty-age-related-hearing-loss-and-the-risk-of-cognitive-31452865","doi":"10.1177/2040622318811000","journal":"Therapeutic advances in chronic disease","n_participants":null,"pmid":"31452865","source_url":"https://pubmed.ncbi.nlm.nih.gov/31452865/","study_design":"case-control study","title":"Sensorial frailty: age-related hearing loss and the risk of cognitive impairment and dementia in later life","title_match":true,"year":2019},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/health-care-management-of-adults-with-down-syndrome-11578024","doi":null,"journal":"American family physician","n_participants":null,"pmid":"11578024","source_url":"https://pubmed.ncbi.nlm.nih.gov/11578024/","study_design":null,"title":"Health care management of adults with Down syndrome","title_match":false,"year":2001},{"alzhub_score":59,"alzhub_url":"https://alzhub.org/study/hearing-impairment-and-cognitive-decline-in-senile-dementia-of-the-3950288","doi":"10.1111/j.1532-5415.1986.tb04204.x","journal":"Journal of the American Geriatrics Society","n_participants":36,"pmid":"3950288","source_url":"https://pubmed.ncbi.nlm.nih.gov/3950288/","study_design":"longitudinal study","title":"Hearing impairment and cognitive decline in senile dementia of the Alzheimer's type","title_match":true,"year":1986},{"alzhub_score":81,"alzhub_url":"https://alzhub.org/study/a-randomized-feasibility-pilot-trial-of-hearing-treatment-for-29067347","doi":"10.1016/j.trci.2017.06.003","journal":"Alzheimer's & dementia (New York, N. Y.)","n_participants":850,"pmid":"29067347","source_url":"https://pubmed.ncbi.nlm.nih.gov/29067347/","study_design":"randomized controlled trial","title":"A randomized feasibility pilot trial of hearing treatment for reducing cognitive decline: Results from the Aging and Cognitive Health Evaluation in Elders Pilot Study","title_match":false,"year":2017},{"alzhub_score":38,"alzhub_url":"https://alzhub.org/study/alzheimer-s-disease-beyond-amyloid-can-the-repetitive-failures-of-32247851","doi":"10.1016/j.bcp.2020.113945","journal":"Biochemical pharmacology","n_participants":null,"pmid":"32247851","source_url":"https://pubmed.ncbi.nlm.nih.gov/32247851/","study_design":null,"title":"Alzheimer's disease beyond amyloid: Can the repetitive failures of amyloid-targeted therapeutics inform future approaches to dementia drug discovery?","title_match":false,"year":2020},{"alzhub_score":72,"alzhub_url":"https://alzhub.org/study/hearing-treatment-for-reducing-cognitive-decline-design-and-methods-30364572","doi":"10.1016/j.trci.2018.08.007","journal":"Alzheimer's & dementia (New York, N. Y.)","n_participants":null,"pmid":"30364572","source_url":"https://pubmed.ncbi.nlm.nih.gov/30364572/","study_design":"randomized controlled trial","title":"Hearing treatment for reducing cognitive decline: Design and methods of the Aging and Cognitive Health Evaluation in Elders randomized controlled trial","title_match":false,"year":2018},{"alzhub_score":55,"alzhub_url":"https://alzhub.org/study/long-term-systemic-inflammation-and-cognitive-impairment-in-a-25123210","doi":"10.1111/jgs.12994","journal":"Journal of the American Geriatrics Society","n_participants":2422,"pmid":"25123210","source_url":"https://pubmed.ncbi.nlm.nih.gov/25123210/","study_design":null,"title":"Long-term systemic inflammation and cognitive impairment in a population-based cohort","title_match":false,"year":2014},{"alzhub_score":86,"alzhub_url":"https://alzhub.org/study/hearing-impairment-mild-cognitive-impairment-and-dementia-a-meta-29430246","doi":"10.1159/000485178","journal":"Dementia and geriatric cognitive disorders extra","n_participants":15521,"pmid":"29430246","source_url":"https://pubmed.ncbi.nlm.nih.gov/29430246/","study_design":"meta-analysis","title":"Hearing Impairment, Mild Cognitive Impairment, and Dementia: A Meta-Analysis of Cohort Studies","title_match":true,"year":2017},{"alzhub_score":47,"alzhub_url":"https://alzhub.org/study/healthy-aging-nutrition-matters-start-early-and-screen-often-33838032","doi":"10.1093/advances/nmab032","journal":"Advances in nutrition (Bethesda, Md.)","n_participants":null,"pmid":"33838032","source_url":"https://pubmed.ncbi.nlm.nih.gov/33838032/","study_design":"narrative review","title":"Healthy Aging-Nutrition Matters: Start Early and Screen Often","title_match":false,"year":2021},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/treatment-of-susac-s-syndrome-18325301","doi":"10.1007/s11940-008-0008-y","journal":"Current treatment options in neurology","n_participants":null,"pmid":"18325301","source_url":"https://pubmed.ncbi.nlm.nih.gov/18325301/","study_design":null,"title":"Treatment of Susac's Syndrome","title_match":false,"year":2008},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/the-effects-of-improving-hearing-in-dementia-12615563","doi":"10.1093/ageing/32.2.189","journal":"Age and ageing","n_participants":null,"pmid":"12615563","source_url":"https://pubmed.ncbi.nlm.nih.gov/12615563/","study_design":null,"title":"The effects of improving hearing in dementia","title_match":false,"year":2003},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/cognitive-decline-dementia-alzheimer-s-disease-and-presbycusis-29937713","doi":"10.3389/fnins.2018.00394","journal":"Frontiers in neuroscience","n_participants":null,"pmid":"29937713","source_url":"https://pubmed.ncbi.nlm.nih.gov/29937713/","study_design":null,"title":"Cognitive Decline, Dementia, Alzheimer's Disease and Presbycusis: Examination of the Possible Molecular Mechanism","title_match":true,"year":2018},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/cockayne-syndrome-in-adults-review-with-clinical-and-pathologic-study-17092472","doi":"10.1177/08830738060210110101","journal":"Journal of child neurology","n_participants":null,"pmid":"17092472","source_url":"https://pubmed.ncbi.nlm.nih.gov/17092472/","study_design":null,"title":"Cockayne syndrome in adults: review with clinical and pathologic study of a new case","title_match":false,"year":2006},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/hearing-impairment-as-a-predictor-of-cognitive-decline-in-dementia-3171050","doi":"10.1111/j.1532-5415.1988.tb04363.x","journal":"Journal of the American Geriatrics Society","n_participants":null,"pmid":"3171050","source_url":"https://pubmed.ncbi.nlm.nih.gov/3171050/","study_design":null,"title":"Hearing impairment as a predictor of cognitive decline in dementia","title_match":true,"year":1988},{"alzhub_score":59,"alzhub_url":"https://alzhub.org/study/hearing-loss-and-risk-of-mild-cognitive-impairment-and-dementia-28420004","doi":"10.1159/000464281","journal":"Dementia and geriatric cognitive disorders","n_participants":1515,"pmid":"28420004","source_url":"https://pubmed.ncbi.nlm.nih.gov/28420004/","study_design":"cross-sectional","title":"Hearing Loss and Risk of Mild Cognitive Impairment and Dementia: Findings from the Singapore Longitudinal Ageing Study","title_match":true,"year":2017},{"alzhub_score":71,"alzhub_url":"https://alzhub.org/study/the-effect-of-decreased-audibility-on-mmse-performance-a-measure-27115241","doi":"10.3766/jaaa.15006","journal":"Journal of the American Academy of Audiology","n_participants":null,"pmid":"27115241","source_url":"https://pubmed.ncbi.nlm.nih.gov/27115241/","study_design":null,"title":"The Effect of Decreased Audibility on MMSE Performance: A Measure Commonly Used for Diagnosing Dementia","title_match":false,"year":2016},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/susac-syndrome-9465860","doi":"10.1097/00005792-199801000-00002","journal":"Medicine","n_participants":null,"pmid":"9465860","source_url":"https://pubmed.ncbi.nlm.nih.gov/9465860/","study_design":null,"title":"Susac syndrome","title_match":false,"year":1998},{"alzhub_score":38,"alzhub_url":"https://alzhub.org/study/reduced-acoustic-startle-response-and-peripheral-hearing-loss-in-the-28133939","doi":"10.1111/gbb.12370","journal":"Genes, brain, and behavior","n_participants":null,"pmid":"28133939","source_url":"https://pubmed.ncbi.nlm.nih.gov/28133939/","study_design":null,"title":"Reduced acoustic startle response and peripheral hearing loss in the 5xFAD mouse model of Alzheimer's disease","title_match":true,"year":2017},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/target-based-selection-of-flavonoids-for-neurodegenerative-disorders-22980637","doi":"10.1016/j.tips.2012.08.002","journal":"Trends in pharmacological sciences","n_participants":null,"pmid":"22980637","source_url":"https://pubmed.ncbi.nlm.nih.gov/22980637/","study_design":null,"title":"Target-based selection of flavonoids for neurodegenerative disorders","title_match":false,"year":2012},{"alzhub_score":83,"alzhub_url":"https://alzhub.org/study/genome-wide-association-meta-analysis-identifies-48-risk-variants-and-35580588","doi":"10.1016/j.ajhg.2022.04.010","journal":"American journal of human genetics","n_participants":723266,"pmid":"35580588","source_url":"https://pubmed.ncbi.nlm.nih.gov/35580588/","study_design":"meta-analysis","title":"Genome-wide association meta-analysis identifies 48 risk variants and highlights the role of the stria vascularis in hearing loss","title_match":true,"year":2022},{"alzhub_score":76,"alzhub_url":"https://alzhub.org/study/hearing-impairment-and-risk-of-alzheimer-s-disease-a-meta-analysis-of-27896493","doi":"10.1007/s10072-016-2779-3","journal":"Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology","n_participants":7461,"pmid":"27896493","source_url":"https://pubmed.ncbi.nlm.nih.gov/27896493/","study_design":"systematic review","title":"Hearing impairment and risk of Alzheimer's disease: a meta-analysis of prospective cohort studies","title_match":true,"year":2017},{"alzhub_score":40,"alzhub_url":"https://alzhub.org/study/age-related-hearing-loss-prevention-of-threshold-declines-cell-loss-27667674","doi":"10.18632/aging.101045","journal":"Aging","n_participants":null,"pmid":"27667674","source_url":"https://pubmed.ncbi.nlm.nih.gov/27667674/","study_design":null,"title":"Age-related hearing loss: prevention of threshold declines, cell loss and apoptosis in spiral ganglion neurons","title_match":true,"year":2016},{"alzhub_score":48,"alzhub_url":"https://alzhub.org/study/identifying-health-conditions-associated-with-alzheimer-s-disease-up-35216751","doi":"10.1016/s2589-7500(21)00275-2","journal":"The Lancet. Digital health","n_participants":214,"pmid":"35216751","source_url":"https://pubmed.ncbi.nlm.nih.gov/35216751/","study_design":null,"title":"Identifying health conditions associated with Alzheimer's disease up to 15 years before diagnosis: an agnostic study of French and British health records","title_match":false,"year":2022},{"alzhub_score":38,"alzhub_url":"https://alzhub.org/study/mir-34a-in-neurophysiology-and-neuropathology-30488149","doi":"10.1007/s12031-018-1231-y","journal":"Journal of molecular neuroscience : MN","n_participants":null,"pmid":"30488149","source_url":"https://pubmed.ncbi.nlm.nih.gov/30488149/","study_design":null,"title":"miR-34a in Neurophysiology and Neuropathology","title_match":false,"year":2019},{"alzhub_score":66,"alzhub_url":"https://alzhub.org/study/interventions-for-hearing-and-vision-impairment-to-improve-outcomes-30244688","doi":"10.1017/s1041610218000728","journal":"International psychogeriatrics","n_participants":null,"pmid":"30244688","source_url":"https://pubmed.ncbi.nlm.nih.gov/30244688/","study_design":"randomized controlled trial","title":"Interventions for hearing and vision impairment to improve outcomes for people with dementia: a scoping review","title_match":false,"year":2019},{"alzhub_score":74,"alzhub_url":"https://alzhub.org/study/association-of-hearing-loss-with-dementia-31365110","doi":"10.1001/jamanetworkopen.2019.8112","journal":"JAMA network open","n_participants":8135,"pmid":"31365110","source_url":"https://pubmed.ncbi.nlm.nih.gov/31365110/","study_design":"cohort study","title":"Association of Hearing Loss With Dementia","title_match":true,"year":2019},{"alzhub_score":52,"alzhub_url":"https://alzhub.org/study/the-effect-of-cognitive-impairment-on-the-accuracy-of-the-presenting-21272958","doi":"10.1016/j.annemergmed.2010.12.002","journal":"Annals of emergency medicine","n_participants":202,"pmid":"21272958","source_url":"https://pubmed.ncbi.nlm.nih.gov/21272958/","study_design":"cross-sectional","title":"The effect of cognitive impairment on the accuracy of the presenting complaint and discharge instruction comprehension in older emergency department patients","title_match":false,"year":2011},{"alzhub_score":50,"alzhub_url":"https://alzhub.org/study/a-population-based-study-of-cognitive-function-in-older-people-with-20847410","doi":"10.3233/jad-2010-100972","journal":"Journal of Alzheimer's disease : JAD","n_participants":1073,"pmid":"20847410","source_url":"https://pubmed.ncbi.nlm.nih.gov/20847410/","study_design":null,"title":"A population-based study of cognitive function in older people with subjective memory complaints","title_match":false,"year":2010},{"alzhub_score":71,"alzhub_url":"https://alzhub.org/study/age-related-hearing-loss-late-life-depression-and-risk-for-incident-32959064","doi":"10.1093/gerona/glaa242","journal":"The journals of gerontology. Series A, Biological sciences and medical sciences","n_participants":8529,"pmid":"32959064","source_url":"https://pubmed.ncbi.nlm.nih.gov/32959064/","study_design":"longitudinal study","title":"Age-Related Hearing Loss, Late-Life Depression, and Risk for Incident Dementia in Older Adults","title_match":true,"year":2021},{"alzhub_score":50,"alzhub_url":"https://alzhub.org/study/hearing-impairment-and-the-risk-of-neurodegenerative-dementia-a-30323320","doi":"10.1038/s41598-018-33325-x","journal":"Scientific reports","n_participants":null,"pmid":"30323320","source_url":"https://pubmed.ncbi.nlm.nih.gov/30323320/","study_design":null,"title":"Hearing impairment and the risk of neurodegenerative dementia: A longitudinal follow-up study using a national sample cohort","title_match":true,"year":2018},{"alzhub_score":60,"alzhub_url":"https://alzhub.org/study/association-between-sensory-impairment-and-dementia-in-older-adults-29319875","doi":"10.1111/jgs.15202","journal":"Journal of the American Geriatrics Society","n_participants":250752,"pmid":"29319875","source_url":"https://pubmed.ncbi.nlm.nih.gov/29319875/","study_design":"cross-sectional","title":"Association Between Sensory Impairment and Dementia in Older Adults: Evidence from China","title_match":false,"year":2018},{"alzhub_score":52,"alzhub_url":"https://alzhub.org/study/the-triple-challenges-associated-with-age-related-comorbidities-in-23510031","doi":"10.1111/jir.12026","journal":"Journal of intellectual disability research : JIDR","n_participants":null,"pmid":"23510031","source_url":"https://pubmed.ncbi.nlm.nih.gov/23510031/","study_design":"longitudinal study","title":"The triple challenges associated with age-related comorbidities in Down syndrome","title_match":false,"year":2014},{"alzhub_score":62,"alzhub_url":"https://alzhub.org/study/carotid-atherosclerosis-and-10-year-changes-in-cognitive-function-22854188","doi":"10.1016/j.atherosclerosis.2012.07.024","journal":"Atherosclerosis","n_participants":1651,"pmid":"22854188","source_url":"https://pubmed.ncbi.nlm.nih.gov/22854188/","study_design":"longitudinal study","title":"Carotid atherosclerosis and 10-year changes in cognitive function","title_match":false,"year":2012},{"alzhub_score":16,"alzhub_url":"https://alzhub.org/study/modifiable-risk-factors-for-alzheimer-disease-and-related-dementias-35587456","doi":"10.15585/mmwr.mm7120a2","journal":"MMWR. Morbidity and mortality weekly report","n_participants":null,"pmid":"35587456","source_url":"https://pubmed.ncbi.nlm.nih.gov/35587456/","study_design":null,"title":"Modifiable Risk Factors for Alzheimer Disease and Related Dementias Among Adults Aged \u226545 Years - United States, 2019","title_match":false,"year":2022},{"alzhub_score":72,"alzhub_url":"https://alzhub.org/study/hearing-impairment-affects-dementia-incidence-an-analysis-based-on-27391486","doi":"10.1371/journal.pone.0156876","journal":"PloS one","n_participants":154783,"pmid":"27391486","source_url":"https://pubmed.ncbi.nlm.nih.gov/27391486/","study_design":"longitudinal study","title":"Hearing Impairment Affects Dementia Incidence. An Analysis Based on Longitudinal Health Claims Data in Germany","title_match":true,"year":2016},{"alzhub_score":59,"alzhub_url":"https://alzhub.org/study/hearing-loss-plasma-neurodegenerative-biomarkers-and-cognitive-40961167","doi":"10.1177/13872877251378675","journal":"Journal of Alzheimer's disease : JAD","n_participants":373,"pmid":"40961167","source_url":"https://pubmed.ncbi.nlm.nih.gov/40961167/","study_design":"cross-sectional","title":"Hearing loss, plasma neurodegenerative biomarkers, and cognitive function: Independent and additive effects","title_match":true,"year":2025},{"alzhub_score":43,"alzhub_url":"https://alzhub.org/study/apoe4-impairs-macrophage-lipophagy-and-promotes-demyelination-of-40258814","doi":"10.1038/s41420-025-02454-4","journal":"Cell death discovery","n_participants":null,"pmid":"40258814","source_url":"https://pubmed.ncbi.nlm.nih.gov/40258814/","study_design":null,"title":"APOE4 impairs macrophage lipophagy and promotes demyelination of spiral ganglion neurons in mouse cochleae","title_match":false,"year":2025},{"alzhub_score":46,"alzhub_url":"https://alzhub.org/study/exploring-the-genetic-relationship-between-hearing-impairment-and-33005726","doi":"10.1002/dad2.12108","journal":"Alzheimer's & dementia (Amsterdam, Netherlands)","n_participants":null,"pmid":"33005726","source_url":"https://pubmed.ncbi.nlm.nih.gov/33005726/","study_design":null,"title":"Exploring the genetic relationship between hearing impairment and Alzheimer's disease","title_match":true,"year":2020},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/alterations-to-cognitive-abilities-and-functional-networks-in-rats-35543862","doi":"10.1007/s11682-022-00643-8","journal":"Brain imaging and behavior","n_participants":null,"pmid":"35543862","source_url":"https://pubmed.ncbi.nlm.nih.gov/35543862/","study_design":null,"title":"Alterations to cognitive abilities and functional networks in rats post broad-band intense noise exposure","title_match":false,"year":2022},{"alzhub_score":48,"alzhub_url":"https://alzhub.org/study/hearing-loss-and-its-link-to-cognitive-impairment-and-dementia-39081997","doi":"10.3389/frdem.2023.1199319","journal":"Frontiers in dementia","n_participants":null,"pmid":"39081997","source_url":"https://pubmed.ncbi.nlm.nih.gov/39081997/","study_design":null,"title":"Hearing loss and its link to cognitive impairment and dementia","title_match":true,"year":2023},{"alzhub_score":45,"alzhub_url":"https://alzhub.org/study/susac-syndrome-challenges-in-the-diagnosis-and-treatment-35136969","doi":"10.1093/brain/awab476","journal":"Brain : a journal of neurology","n_participants":null,"pmid":"35136969","source_url":"https://pubmed.ncbi.nlm.nih.gov/35136969/","study_design":null,"title":"Susac syndrome: challenges in the diagnosis and treatment","title_match":false,"year":2022},{"alzhub_score":39,"alzhub_url":"https://alzhub.org/study/presbyacusis-31579062","doi":"10.17116/otorino20198404167","journal":"Vestnik otorinolaringologii","n_participants":null,"pmid":"31579062","source_url":"https://pubmed.ncbi.nlm.nih.gov/31579062/","study_design":null,"title":"[Presbyacusis]","title_match":false,"year":2019},{"alzhub_score":52,"alzhub_url":"https://alzhub.org/study/trends-and-mechanisms-of-alzheimer-s-disease-and-hearing-impairment-a-40499729","doi":"10.1016/j.arr.2025.102799","journal":"Ageing research reviews","n_participants":349,"pmid":"40499729","source_url":"https://pubmed.ncbi.nlm.nih.gov/40499729/","study_design":null,"title":"Trends and mechanisms of Alzheimer's disease and hearing impairment: A 20-year perspective","title_match":true,"year":2025},{"alzhub_score":48,"alzhub_url":"https://alzhub.org/study/relationship-between-hearing-impairment-and-dementia-and-cognitive-39385207","doi":"10.1186/s13195-024-01586-6","journal":"Alzheimer's research & therapy","n_participants":null,"pmid":"39385207","source_url":"https://pubmed.ncbi.nlm.nih.gov/39385207/","study_design":null,"title":"Relationship between hearing impairment and dementia and cognitive function: a Mendelian randomization study","title_match":true,"year":2024},{"alzhub_score":89,"alzhub_url":"https://alzhub.org/study/adult-onset-hearing-loss-and-incident-cognitive-impairment-and-38788800","doi":"10.1016/j.arr.2024.102346","journal":"Ageing research reviews","n_participants":1548754,"pmid":"38788800","source_url":"https://pubmed.ncbi.nlm.nih.gov/38788800/","study_design":"meta-analysis","title":"Adult-onset hearing loss and incident cognitive impairment and dementia - A systematic review and meta-analysis of cohort studies","title_match":true,"year":2024},{"alzhub_score":46,"alzhub_url":"https://alzhub.org/study/hearing-loss-promotes-alzheimer-s-disease-38491290","doi":"10.1038/s43587-024-00606-2","journal":"Nature aging","n_participants":null,"pmid":"38491290","source_url":"https://pubmed.ncbi.nlm.nih.gov/38491290/","study_design":null,"title":"Hearing loss promotes Alzheimer's disease","title_match":true,"year":2024},{"alzhub_score":43,"alzhub_url":"https://alzhub.org/study/hearing-loss-and-alzheimer-disease-39436630","doi":"10.1007/7854_2024_526","journal":"Current topics in behavioral neurosciences","n_participants":null,"pmid":"39436630","source_url":"https://pubmed.ncbi.nlm.nih.gov/39436630/","study_design":null,"title":"Hearing Loss and Alzheimer Disease","title_match":true,"year":2025},{"alzhub_score":46,"alzhub_url":"https://alzhub.org/study/hearing-interventions-to-prevent-dementia-30767054","doi":"10.1007/s00106-019-0617-7","journal":"HNO","n_participants":null,"pmid":"30767054","source_url":"https://pubmed.ncbi.nlm.nih.gov/30767054/","study_design":null,"title":"Hearing interventions to prevent dementia","title_match":false,"year":2019},{"alzhub_score":38,"alzhub_url":"https://alzhub.org/study/hearing-impairment-and-dementia-25217286","doi":"10.1007/s00391-014-0808-5","journal":"Zeitschrift fur Gerontologie und Geriatrie","n_participants":null,"pmid":"25217286","source_url":"https://pubmed.ncbi.nlm.nih.gov/25217286/","study_design":null,"title":"[Hearing impairment and dementia]","title_match":true,"year":2015},{"alzhub_score":39,"alzhub_url":"https://alzhub.org/study/hearing-loss-and-alzheimer-s-disease-a-review-32009339","doi":"10.5935/0946-5448.20190014","journal":"The international tinnitus journal","n_participants":null,"pmid":"32009339","source_url":"https://pubmed.ncbi.nlm.nih.gov/32009339/","study_design":null,"title":"Hearing loss and Alzheimer's disease: A Review","title_match":true,"year":2019},{"alzhub_score":39,"alzhub_url":"https://alzhub.org/study/hearing-loss-in-the-elderly-29661329","doi":"10.1016/j.cger.2018.01.001","journal":"Clinics in geriatric medicine","n_participants":null,"pmid":"29661329","source_url":"https://pubmed.ncbi.nlm.nih.gov/29661329/","study_design":null,"title":"Hearing Loss in the Elderly","title_match":true,"year":2018},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/hearing-loss-and-brain-disorders-a-review-of-multiple-pathologies-34993346","doi":"10.1515/med-2021-0402","journal":"Open medicine (Warsaw, Poland)","n_participants":null,"pmid":"34993346","source_url":"https://pubmed.ncbi.nlm.nih.gov/34993346/","study_design":null,"title":"Hearing loss and brain disorders: A review of multiple pathologies","title_match":true,"year":2022},{"alzhub_score":63,"alzhub_url":"https://alzhub.org/study/dementia-and-hearing-aid-use-and-cessation-a-national-study-37713529","doi":"10.1044/2023_aja-23-00038","journal":"American journal of audiology","n_participants":null,"pmid":"37713529","source_url":"https://pubmed.ncbi.nlm.nih.gov/37713529/","study_design":"longitudinal study","title":"Dementia and Hearing Aid Use and Cessation: A National Study","title_match":true,"year":2023},{"alzhub_score":66,"alzhub_url":"https://alzhub.org/study/dual-sensory-impairment-and-cognitive-impairment-in-the-korean-33827964","doi":"10.1212/wnl.0000000000011845","journal":"Neurology","n_participants":null,"pmid":"33827964","source_url":"https://pubmed.ncbi.nlm.nih.gov/33827964/","study_design":"cohort study","title":"Dual Sensory Impairment and Cognitive Impairment in the Korean Longitudinal Elderly Cohort","title_match":false,"year":2021},{"alzhub_score":88,"alzhub_url":"https://alzhub.org/study/hearing-loss-and-dementia-a-meta-analysis-of-prospective-cohort-34305572","doi":"10.3389/fnagi.2021.695117","journal":"Frontiers in aging neuroscience","n_participants":726900,"pmid":"34305572","source_url":"https://pubmed.ncbi.nlm.nih.gov/34305572/","study_design":"meta-analysis","title":"Hearing Loss and Dementia: A Meta-Analysis of Prospective Cohort Studies","title_match":true,"year":2021},{"alzhub_score":39,"alzhub_url":"https://alzhub.org/study/peripheral-and-central-hearing-impairment-and-their-relationship-with-30939073","doi":"10.1080/14992027.2019.1591644","journal":"International journal of audiology","n_participants":null,"pmid":"30939073","source_url":"https://pubmed.ncbi.nlm.nih.gov/30939073/","study_design":"narrative review","title":"Peripheral and central hearing impairment and their relationship with cognition: a review","title_match":true,"year":2019},{"alzhub_score":64,"alzhub_url":"https://alzhub.org/study/vision-impairment-and-patient-activation-among-medicare-beneficiaries-35593136","doi":"10.1080/09286586.2022.2078495","journal":"Ophthalmic epidemiology","n_participants":6683,"pmid":"35593136","source_url":"https://pubmed.ncbi.nlm.nih.gov/35593136/","study_design":"cross-sectional","title":"Vision Impairment and Patient Activation among Medicare Beneficiaries","title_match":false,"year":2023},{"alzhub_score":61,"alzhub_url":"https://alzhub.org/study/risk-of-dementia-with-hearing-impairment-and-social-isolation-38756910","doi":"10.1002/dad2.12586","journal":"Alzheimer's & dementia (Amsterdam, Netherlands)","n_participants":2745,"pmid":"38756910","source_url":"https://pubmed.ncbi.nlm.nih.gov/38756910/","study_design":null,"title":"Risk of dementia with hearing impairment and social isolation","title_match":true,"year":2024},{"alzhub_score":70,"alzhub_url":"https://alzhub.org/study/hearing-impairment-and-cognitive-decline-in-older-community-dwelling-30753308","doi":"10.1093/gerona/glz035","journal":"The journals of gerontology. Series A, Biological sciences and medical sciences","n_participants":1164,"pmid":"30753308","source_url":"https://pubmed.ncbi.nlm.nih.gov/30753308/","study_design":"longitudinal study","title":"Hearing Impairment and Cognitive Decline in Older, Community-Dwelling Adults","title_match":true,"year":2020},{"alzhub_score":61,"alzhub_url":"https://alzhub.org/study/association-of-genetic-risk-for-alzheimer-disease-and-hearing-32878991","doi":"10.1212/wnl.0000000000010709","journal":"Neurology","n_participants":80074,"pmid":"32878991","source_url":"https://pubmed.ncbi.nlm.nih.gov/32878991/","study_design":null,"title":"Association of genetic risk for Alzheimer disease and hearing impairment","title_match":true,"year":2020},{"alzhub_score":57,"alzhub_url":"https://alzhub.org/study/self-reported-hearing-loss-hearing-aid-use-and-cognitive-function-37304046","doi":"10.18063/ijps.v8i1.1308","journal":"International journal of population studies","n_participants":null,"pmid":"37304046","source_url":"https://pubmed.ncbi.nlm.nih.gov/37304046/","study_design":"longitudinal study","title":"Self-reported hearing loss, hearing aid use, and cognitive function among U.S. older adults","title_match":true,"year":2022},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/does-hearing-loss-lead-to-dementia-a-review-of-the-literature-32814645","doi":"10.1016/j.heares.2020.108038","journal":"Hearing research","n_participants":null,"pmid":"32814645","source_url":"https://pubmed.ncbi.nlm.nih.gov/32814645/","study_design":null,"title":"Does hearing loss lead to dementia? A review of the literature","title_match":true,"year":2021},{"alzhub_score":39,"alzhub_url":"https://alzhub.org/study/age-related-hearing-loss-innovations-in-hearing-augmentation-29735277","doi":"10.1016/j.otc.2018.03.002","journal":"Otolaryngologic clinics of North America","n_participants":null,"pmid":"29735277","source_url":"https://pubmed.ncbi.nlm.nih.gov/29735277/","study_design":null,"title":"Age-Related Hearing Loss: Innovations in Hearing Augmentation","title_match":true,"year":2018},{"alzhub_score":57,"alzhub_url":"https://alzhub.org/study/the-laterality-of-early-age-related-hearing-loss-and-brain-amyloid-35147609","doi":"10.1097/mao.0000000000003454","journal":"Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology","n_participants":null,"pmid":"35147609","source_url":"https://pubmed.ncbi.nlm.nih.gov/35147609/","study_design":"cohort study","title":"The Laterality of Early Age-Related Hearing Loss and Brain \u03b2-Amyloid","title_match":true,"year":2022},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/sensorineural-hearing-loss-may-lead-to-dementia-related-pathological-34082124","doi":"10.1016/j.nbd.2021.105408","journal":"Neurobiology of disease","n_participants":null,"pmid":"34082124","source_url":"https://pubmed.ncbi.nlm.nih.gov/34082124/","study_design":null,"title":"Sensorineural hearing loss may lead to dementia-related pathological changes in hippocampal neurons","title_match":true,"year":2021},{"alzhub_score":48,"alzhub_url":"https://alzhub.org/study/hearing-all-about-donepezil-its-role-in-the-field-of-auditory-41141199","doi":"10.7759/cureus.93143","journal":"Cureus","n_participants":null,"pmid":"41141199","source_url":"https://pubmed.ncbi.nlm.nih.gov/41141199/","study_design":null,"title":"Hearing All About Donepezil: Its Role in the Field of Auditory Processing","title_match":false,"year":2025},{"alzhub_score":61,"alzhub_url":"https://alzhub.org/study/audiometric-age-related-hearing-loss-and-cognition-in-the-hispanic-31183502","doi":"10.1093/gerona/glz119","journal":"The journals of gerontology. Series A, Biological sciences and medical sciences","n_participants":5277,"pmid":"31183502","source_url":"https://pubmed.ncbi.nlm.nih.gov/31183502/","study_design":"cross-sectional","title":"Audiometric Age-Related Hearing Loss and Cognition in the Hispanic Community Health Study","title_match":true,"year":2020},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/hearing-impairment-and-cognition-in-an-aging-world-34008037","doi":"10.1007/s10162-021-00799-y","journal":"Journal of the Association for Research in Otolaryngology : JARO","n_participants":null,"pmid":"34008037","source_url":"https://pubmed.ncbi.nlm.nih.gov/34008037/","study_design":null,"title":"Hearing Impairment and Cognition in an Aging World","title_match":true,"year":2021},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/hearing-loss-and-cognitive-impairment-epidemiology-common-34685474","doi":"10.3390/life11101102","journal":"Life (Basel, Switzerland)","n_participants":null,"pmid":"34685474","source_url":"https://pubmed.ncbi.nlm.nih.gov/34685474/","study_design":null,"title":"Hearing Loss and Cognitive Impairment: Epidemiology, Common Pathophysiological Findings, and Treatment Considerations","title_match":true,"year":2021},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/micrornas-related-to-cognitive-impairment-after-hearing-loss-32646202","doi":"10.21053/ceo.2019.01382","journal":"Clinical and experimental otorhinolaryngology","n_participants":null,"pmid":"32646202","source_url":"https://pubmed.ncbi.nlm.nih.gov/32646202/","study_design":null,"title":"MicroRNAs Related to Cognitive Impairment After Hearing Loss","title_match":true,"year":2021},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/early-noise-induced-hearing-loss-accelerates-presbycusis-altering-35197842","doi":"10.3389/fnagi.2022.803973","journal":"Frontiers in aging neuroscience","n_participants":null,"pmid":"35197842","source_url":"https://pubmed.ncbi.nlm.nih.gov/35197842/","study_design":null,"title":"Early Noise-Induced Hearing Loss Accelerates Presbycusis Altering Aging Processes in the Cochlea","title_match":true,"year":2022},{"alzhub_score":55,"alzhub_url":"https://alzhub.org/study/associations-between-sleep-duration-and-sensory-impairments-among-35754970","doi":"10.3389/fnagi.2022.910231","journal":"Frontiers in aging neuroscience","n_participants":null,"pmid":"35754970","source_url":"https://pubmed.ncbi.nlm.nih.gov/35754970/","study_design":"cross-sectional","title":"Associations Between Sleep Duration and Sensory Impairments Among Older Adults in China","title_match":false,"year":2022},{"alzhub_score":64,"alzhub_url":"https://alzhub.org/study/the-association-between-early-age-related-hearing-loss-and-brain-32644260","doi":"10.1002/lary.28859","journal":"The Laryngoscope","n_participants":98,"pmid":"32644260","source_url":"https://pubmed.ncbi.nlm.nih.gov/32644260/","study_design":"cohort study","title":"The Association Between Early Age-Related Hearing Loss and Brain \u03b2-Amyloid","title_match":true,"year":2021},{"alzhub_score":61,"alzhub_url":"https://alzhub.org/study/impact-of-concurrent-visual-and-hearing-impairment-on-incident-38363608","doi":"10.3233/jad-230806","journal":"Journal of Alzheimer's disease : JAD","n_participants":14186,"pmid":"38363608","source_url":"https://pubmed.ncbi.nlm.nih.gov/38363608/","study_design":null,"title":"Impact of Concurrent Visual and Hearing Impairment on Incident Alzheimer's Disease: The LIFE Study","title_match":true,"year":2024},{"alzhub_score":43,"alzhub_url":"https://alzhub.org/study/neuropathological-findings-of-dementia-associated-with-subjective-31498297","doi":"10.1097/mao.0000000000002381","journal":"Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology","n_participants":null,"pmid":"31498297","source_url":"https://pubmed.ncbi.nlm.nih.gov/31498297/","study_design":null,"title":"Neuropathological Findings of Dementia Associated With Subjective Hearing Loss","title_match":true,"year":2019},{"alzhub_score":71,"alzhub_url":"https://alzhub.org/study/enablers-and-barriers-to-hearing-aid-use-in-people-living-with-38235997","doi":"10.1177/07334648231225346","journal":"Journal of applied gerontology : the official journal of the Southern Gerontological Society","n_participants":null,"pmid":"38235997","source_url":"https://pubmed.ncbi.nlm.nih.gov/38235997/","study_design":"randomized controlled trial","title":"Enablers and Barriers to Hearing aid Use in People Living With Dementia","title_match":true,"year":2024},{"alzhub_score":82,"alzhub_url":"https://alzhub.org/study/hearing-screening-for-older-adults-with-cognitive-impairment-a-38973326","doi":"10.7874/jao.2023.00507","journal":"Journal of audiology & otology","n_participants":1071,"pmid":"38973326","source_url":"https://pubmed.ncbi.nlm.nih.gov/38973326/","study_design":"systematic review","title":"Hearing Screening for Older Adults With Cognitive Impairment: A Systematic Review","title_match":false,"year":2024},{"alzhub_score":71,"alzhub_url":"https://alzhub.org/study/do-self-reported-hearing-and-visual-impairments-predict-longitudinal-33734430","doi":"10.1111/jgs.17074","journal":"Journal of the American Geriatrics Society","n_participants":3497,"pmid":"33734430","source_url":"https://pubmed.ncbi.nlm.nih.gov/33734430/","study_design":"cohort study","title":"Do self-reported hearing and visual impairments predict longitudinal dementia in older adults?","title_match":false,"year":2021},{"alzhub_score":39,"alzhub_url":"https://alzhub.org/study/interplay-between-nutrition-and-hearing-loss-state-of-art-30586880","doi":"10.3390/nu11010035","journal":"Nutrients","n_participants":null,"pmid":"30586880","source_url":"https://pubmed.ncbi.nlm.nih.gov/30586880/","study_design":null,"title":"Interplay between Nutrition and Hearing Loss: State of Art","title_match":true,"year":2018},{"alzhub_score":57,"alzhub_url":"https://alzhub.org/study/cognitive-change-in-prevalent-and-incident-hearing-loss-the-38236753","doi":"10.1002/alz.13606","journal":"Alzheimer's & dementia : the journal of the Alzheimer's Association","n_participants":1823,"pmid":"38236753","source_url":"https://pubmed.ncbi.nlm.nih.gov/38236753/","study_design":null,"title":"Cognitive change in prevalent and incident hearing loss: The Maastricht Aging Study","title_match":true,"year":2024},{"alzhub_score":59,"alzhub_url":"https://alzhub.org/study/factors-associated-with-hearing-aid-use-among-medicare-beneficiaries-34316520","doi":"10.1093/geroni/igab021","journal":"Innovation in aging","n_participants":5146,"pmid":"34316520","source_url":"https://pubmed.ncbi.nlm.nih.gov/34316520/","study_design":"cross-sectional","title":"Factors Associated With Hearing Aid Use Among Medicare Beneficiaries","title_match":true,"year":2021},{"alzhub_score":43,"alzhub_url":"https://alzhub.org/study/hearing-loss-and-cognitive-decline-in-the-aging-population-emerging-38920961","doi":"10.3390/audiolres14030040","journal":"Audiology research","n_participants":null,"pmid":"38920961","source_url":"https://pubmed.ncbi.nlm.nih.gov/38920961/","study_design":null,"title":"Hearing Loss and Cognitive Decline in the Aging Population: Emerging Perspectives in Audiology","title_match":true,"year":2024},{"alzhub_score":48,"alzhub_url":"https://alzhub.org/study/gender-differences-in-the-association-between-hearing-loss-and-31510756","doi":"10.1177/1533317519871167","journal":"American journal of Alzheimer's disease and other dementias","n_participants":655,"pmid":"31510756","source_url":"https://pubmed.ncbi.nlm.nih.gov/31510756/","study_design":null,"title":"Gender Differences in the Association Between Hearing Loss and Cognitive Function","title_match":true,"year":2020},{"alzhub_score":77,"alzhub_url":"https://alzhub.org/study/hidden-dangers-does-multisensory-impairments-accompanying-visual-38678684","doi":"10.1016/j.jpsychires.2024.04.041","journal":"Journal of psychiatric research","n_participants":500000,"pmid":"38678684","source_url":"https://pubmed.ncbi.nlm.nih.gov/38678684/","study_design":"cohort study","title":"Hidden dangers: Does multisensory impairments accompanying visual impairment increase dementia risk","title_match":false,"year":2024},{"alzhub_score":39,"alzhub_url":"https://alzhub.org/study/hearing-aids-indications-technology-adaptation-and-quality-control-29279726","doi":"10.3205/cto000147","journal":"GMS current topics in otorhinolaryngology, head and neck surgery","n_participants":null,"pmid":"29279726","source_url":"https://pubmed.ncbi.nlm.nih.gov/29279726/","study_design":null,"title":"Hearing aids: indications, technology, adaptation, and quality control","title_match":true,"year":2017},{"alzhub_score":50,"alzhub_url":"https://alzhub.org/study/importance-of-loneliness-in-behavioral-and-psychological-symptoms-of-33091165","doi":"10.1002/gps.5450","journal":"International journal of geriatric psychiatry","n_participants":152,"pmid":"33091165","source_url":"https://pubmed.ncbi.nlm.nih.gov/33091165/","study_design":null,"title":"Importance of loneliness in behavioral and psychological symptoms of dementia","title_match":false,"year":2021},{"alzhub_score":63,"alzhub_url":"https://alzhub.org/study/association-of-midlife-hearing-impairment-and-hearing-aid-use-with-40595016","doi":"10.1038/s43587-025-00914-1","journal":"Nature aging","n_participants":null,"pmid":"40595016","source_url":"https://pubmed.ncbi.nlm.nih.gov/40595016/","study_design":"cohort study","title":"Association of midlife hearing impairment and hearing aid use with incident dementia: analysis of two UK-based longitudinal cohort studies","title_match":true,"year":2025},{"alzhub_score":52,"alzhub_url":"https://alzhub.org/study/peripheral-hearing-loss-at-age-70-predicts-brain-atrophy-and-38569877","doi":"10.1136/jnnp-2023-333101","journal":"Journal of neurology, neurosurgery, and psychiatry","n_participants":287,"pmid":"38569877","source_url":"https://pubmed.ncbi.nlm.nih.gov/38569877/","study_design":null,"title":"Peripheral hearing loss at age 70 predicts brain atrophy and associated cognitive change","title_match":true,"year":2024},{"alzhub_score":48,"alzhub_url":"https://alzhub.org/study/dementia-prevention-and-primary-care-estimation-of-the-target-32877931","doi":"10.1055/a-1227-6287","journal":"Fortschritte der Neurologie-Psychiatrie","n_participants":51,"pmid":"32877931","source_url":"https://pubmed.ncbi.nlm.nih.gov/32877931/","study_design":null,"title":"[Dementia prevention and primary care: Estimation of the target population]","title_match":false,"year":2021},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/towards-a-consensus-on-alzheimer-s-disease-comorbidity-34640387","doi":"10.3390/jcm10194360","journal":"Journal of clinical medicine","n_participants":null,"pmid":"34640387","source_url":"https://pubmed.ncbi.nlm.nih.gov/34640387/","study_design":null,"title":"Towards a Consensus on Alzheimer's Disease Comorbidity?","title_match":false,"year":2021},{"alzhub_score":48,"alzhub_url":"https://alzhub.org/study/population-attributable-fraction-of-modifiable-risk-factors-for-35229017","doi":"10.1002/dad2.12273","journal":"Alzheimer's & dementia (Amsterdam, Netherlands)","n_participants":null,"pmid":"35229017","source_url":"https://pubmed.ncbi.nlm.nih.gov/35229017/","study_design":null,"title":"Population attributable fraction of modifiable risk factors for dementia in Chile","title_match":false,"year":2022},{"alzhub_score":71,"alzhub_url":"https://alzhub.org/study/modifiable-risk-factors-for-stroke-dementia-and-late-life-depression-40180437","doi":"10.1136/jnnp-2024-334925","journal":"Journal of neurology, neurosurgery, and psychiatry","n_participants":null,"pmid":"40180437","source_url":"https://pubmed.ncbi.nlm.nih.gov/40180437/","study_design":"meta-analysis","title":"Modifiable risk factors for stroke, dementia and late-life depression: a systematic review and DALY-weighted risk factors for a composite outcome","title_match":false,"year":2025},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/cognitive-and-behavioral-effects-of-hearing-loss-36004783","doi":"10.1097/moo.0000000000000825","journal":"Current opinion in otolaryngology & head and neck surgery","n_participants":null,"pmid":"36004783","source_url":"https://pubmed.ncbi.nlm.nih.gov/36004783/","study_design":null,"title":"Cognitive and behavioral effects of hearing loss","title_match":true,"year":2022},{"alzhub_score":43,"alzhub_url":"https://alzhub.org/study/causal-association-between-particulate-matter-2-5-and-alzheimer-s-38873321","doi":"10.3389/fpubh.2024.1343915","journal":"Frontiers in public health","n_participants":null,"pmid":"38873321","source_url":"https://pubmed.ncbi.nlm.nih.gov/38873321/","study_design":null,"title":"Causal association between particulate matter 2.5 and Alzheimer's disease: a Mendelian randomization study","title_match":false,"year":2024},{"alzhub_score":43,"alzhub_url":"https://alzhub.org/study/nutrition-exercise-and-cognitive-rehabilitation-for-dementia-38854809","doi":"10.14789/jmj.jmj23-0032-r","journal":"Juntendo Iji zasshi = Juntendo medical journal","n_participants":null,"pmid":"38854809","source_url":"https://pubmed.ncbi.nlm.nih.gov/38854809/","study_design":null,"title":"Nutrition, Exercise, and Cognitive Rehabilitation for Dementia Prevention","title_match":false,"year":2024},{"alzhub_score":71,"alzhub_url":"https://alzhub.org/study/dementia-and-communication-comorbidities-within-the-context-of-41345569","doi":"10.1186/s12877-025-06622-0","journal":"BMC geriatrics","n_participants":228,"pmid":"41345569","source_url":"https://pubmed.ncbi.nlm.nih.gov/41345569/","study_design":"cohort study","title":"Dementia and communication comorbidities within the context of caregiver support systems: a scoping review","title_match":false,"year":2025},{"alzhub_score":16,"alzhub_url":"https://alzhub.org/study/racial-and-ethnic-differences-in-subjective-cognitive-decline-united-36893045","doi":"10.15585/mmwr.mm7210a1","journal":"MMWR. Morbidity and mortality weekly report","n_participants":null,"pmid":"36893045","source_url":"https://pubmed.ncbi.nlm.nih.gov/36893045/","study_design":null,"title":"Racial and Ethnic Differences in Subjective Cognitive Decline - United States, 2015-2020","title_match":false,"year":2023},{"alzhub_score":16,"alzhub_url":"https://alzhub.org/study/cognition-in-healthy-aging-ages-36-to-108-associations-with-dementia-4c319601","doi":"10.64898/2026.10.25.26366428","journal":"medRxiv","n_participants":1396,"pmid":null,"source_url":"https://doi.org/10.64898/2026.10.25.26366428","study_design":null,"title":"Cognition in healthy aging, ages 36 to 108: Associations with dementia risk factors and neurodegenerative disease biomarkers","title_match":false,"year":2026},{"alzhub_score":16,"alzhub_url":"https://alzhub.org/study/retinal-biomarkers-and-dementia-risk-a-review-of-evidence-across-the-e8939dca","doi":"10.31234/osf.io/xh7g6_v1","journal":"PsyArXiv","n_participants":null,"pmid":null,"source_url":"https://doi.org/10.31234/osf.io/xh7g6_v1","study_design":null,"title":"Retinal biomarkers and dementia risk: A review of evidence across the 14 Lancet modifiable risk factors for dementia","title_match":false,"year":2026},{"alzhub_score":16,"alzhub_url":"https://alzhub.org/study/building-cognitive-lines-of-defense-a-life-course-prevention-strategy-9d3fb2a4","doi":"10.21203/rs.3.rs-10476642/v1","journal":"Research Square","n_participants":null,"pmid":null,"source_url":"https://doi.org/10.21203/rs.3.rs-10476642/v1","study_design":null,"title":"Building Cognitive Lines of Defense: A Life-Course Prevention Strategy for Alzheimer's Disease\u2014An Evidence-Based Multi-Stage Intervention Protocol","title_match":false,"year":2026},{"alzhub_score":16,"alzhub_url":"https://alzhub.org/study/interacting-role-of-social-determinants-of-health-and-hearing-loss-on-ca226f12","doi":"10.21203/rs.3.rs-11406227/v1","journal":"Research Square","n_participants":2397,"pmid":null,"source_url":"https://doi.org/10.21203/rs.3.rs-11406227/v1","study_design":null,"title":"Interacting Role of Social Determinants of Health and Hearing Loss on Cognitive Decline: An ACTIVE Longitudinal Study","title_match":true,"year":2026},{"alzhub_score":16,"alzhub_url":"https://alzhub.org/study/modifiable-risk-factors-for-dementia-across-the-europe-regional-f6c44b9b","doi":"10.21203/rs.3.rs-9835142/v1","journal":"Research Square","n_participants":40000,"pmid":null,"source_url":"https://doi.org/10.21203/rs.3.rs-9835142/v1","study_design":null,"title":"Modifiable Risk Factors for Dementia across the Europe: regional comparative studyusing SHARE data","title_match":false,"year":2026},{"alzhub_score":16,"alzhub_url":"https://alzhub.org/study/can-modifiable-dementia-risk-factors-help-account-for-the-predictive-ba2a884f","doi":"10.31234/osf.io/tg8ej_v1","journal":"PsyArXiv","n_participants":null,"pmid":null,"source_url":"https://doi.org/10.31234/osf.io/tg8ej_v1","study_design":"longitudinal study","title":"Can modifiable dementia risk factors help account for the predictive link between personality and midlife cognitive health? Evidence from a 17-year longitudinal study of Mexican-origin adults","title_match":false,"year":2026},{"alzhub_score":48,"alzhub_url":"https://alzhub.org/study/linking-modifiable-risk-factors-to-vascular-and-neurodegenerative-0bacb0b1","doi":"10.64898/2026.02.28.26347178","journal":"GeroScience","n_participants":null,"pmid":null,"source_url":"https://doi.org/10.64898/2026.02.28.26347178","study_design":"cross-sectional","title":"Linking Modifiable Risk Factors to Vascular and Neurodegenerative Brain Changes","title_match":false,"year":2026},{"alzhub_score":16,"alzhub_url":"https://alzhub.org/study/hearing-loss-as-a-modifiable-risk-factor-for-dementia-e06f5eda","doi":"10.64898/2026.03.16.26348518","journal":"medRxiv","n_participants":16270,"pmid":null,"source_url":"https://doi.org/10.64898/2026.03.16.26348518","study_design":null,"title":"Hearing Loss as a Modifiable Risk Factor for Dementia","title_match":true,"year":2026},{"alzhub_score":16,"alzhub_url":"https://alzhub.org/study/a-multidomain-intrinsic-capacity-score-tracks-longitudinal-health-8dfce9e2","doi":"10.64898/2026.04.10.26350621","journal":"medRxiv","n_participants":null,"pmid":null,"source_url":"https://doi.org/10.64898/2026.04.10.26350621","study_design":"cross-sectional","title":"A multidomain intrinsic capacity score tracks longitudinal health trajectories in the UK Biobank","title_match":false,"year":2026},{"alzhub_score":72,"alzhub_url":"https://alzhub.org/study/loneliness-as-a-pathway-linking-hearing-decline-to-cognitive-aging-f71c1569","doi":"10.64898/2026.04.16.26351059","journal":"Alzheimer's & dementia : the journal of the Alzheimer's Association","n_participants":10375,"pmid":null,"source_url":"https://doi.org/10.64898/2026.04.16.26351059","study_design":"longitudinal study","title":"Loneliness as a Pathway Linking Hearing Decline to Cognitive Aging: Longitudinal and Genetic Evidence","title_match":false,"year":2026},{"alzhub_score":16,"alzhub_url":"https://alzhub.org/study/crossmodal-plasticity-effects-of-hearing-loss-and-ageing-in-the-human-1aad7f20","doi":"10.64898/2026.06.08.730968","journal":"bioRxiv","n_participants":null,"pmid":null,"source_url":"https://doi.org/10.64898/2026.06.08.730968","study_design":null,"title":"Crossmodal plasticity effects of hearing loss and ageing in the human auditory cortex","title_match":true,"year":2026},{"alzhub_score":16,"alzhub_url":"https://alzhub.org/study/age-related-speech-in-noise-hearing-loss-in-parkinsons-disease-and-a3ec8995","doi":"10.64898/2026.06.08.26355175","journal":"medRxiv","n_participants":null,"pmid":null,"source_url":"https://doi.org/10.64898/2026.06.08.26355175","study_design":"longitudinal study","title":"Age-Related Speech-in-Noise Hearing Loss in Parkinson\u2019s Disease and APOE E4 Carriers","title_match":true,"year":2026},{"alzhub_score":16,"alzhub_url":"https://alzhub.org/study/alzheimer-disease-amyloid-pathology-accelerates-age-related-hearing-b3cc5f32","doi":"10.64898/2026.05.25.727095","journal":"bioRxiv","n_participants":null,"pmid":null,"source_url":"https://doi.org/10.64898/2026.05.25.727095","study_design":null,"title":"Alzheimer disease \u03b2-amyloid pathology accelerates age-related hearing loss: evidence from App NL-F \u201cknock-in\u201d mice","title_match":true,"year":2026},{"alzhub_score":16,"alzhub_url":"https://alzhub.org/study/small-palpebral-fissure-as-a-significant-risk-factor-for-glaucoma-4246e032","doi":"10.64898/2026.05.27.26354208","journal":"medRxiv","n_participants":339,"pmid":null,"source_url":"https://doi.org/10.64898/2026.05.27.26354208","study_design":null,"title":"Small palpebral fissure as a significant risk factor for glaucoma surgery failure","title_match":false,"year":2026},{"alzhub_score":16,"alzhub_url":"https://alzhub.org/study/multi-site-mri-analysis-of-morphometric-differences-in-brain-regions-f6e523dc","doi":"10.64898/2026.03.06.710136","journal":"bioRxiv","n_participants":null,"pmid":null,"source_url":"https://doi.org/10.64898/2026.03.06.710136","study_design":"post-hoc analysis","title":"Multi-site MRI analysis of morphometric differences in brain regions in the presence of hearing loss and tinnitus across the adult lifespan","title_match":true,"year":2026},{"alzhub_score":16,"alzhub_url":"https://alzhub.org/study/physiological-histological-and-cognitive-characterization-of-a-rhesus-155df2b8","doi":"10.64898/2026.03.24.714040","journal":"bioRxiv","n_participants":null,"pmid":null,"source_url":"https://doi.org/10.64898/2026.03.24.714040","study_design":null,"title":"Physiological, Histological, and Cognitive Characterization of a Rhesus Macaque Model of Presbycusis","title_match":true,"year":2026},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/mobile-applications-to-detect-hearing-impairment-opportunities-and-31656337","doi":"10.2471/blt.18.227728","journal":"Bulletin of the World Health Organization","n_participants":null,"pmid":"31656337","source_url":"https://pubmed.ncbi.nlm.nih.gov/31656337/","study_design":null,"title":"Mobile applications to detect hearing impairment: opportunities and challenges","title_match":true,"year":2019},{"alzhub_score":53,"alzhub_url":"https://alzhub.org/study/unveiling-the-potential-of-the-digits-in-noise-test-as-a-hearing-40938770","doi":"10.1177/13872877251376949","journal":"Journal of Alzheimer's disease : JAD","n_participants":93,"pmid":"40938770","source_url":"https://pubmed.ncbi.nlm.nih.gov/40938770/","study_design":null,"title":"Unveiling the potential of the Digits-in-Noise test as a hearing screening tool for older adults with cognitive impairment","title_match":false,"year":2026},{"alzhub_score":62,"alzhub_url":"https://alzhub.org/study/web-based-assessment-of-cognition-and-dementia-risk-factors-in-over-40854096","doi":"10.2196/69867","journal":"JMIR aging","n_participants":3214,"pmid":"40854096","source_url":"https://pubmed.ncbi.nlm.nih.gov/40854096/","study_design":null,"title":"Web-Based Assessment of Cognition and Dementia Risk Factors in Over 3000 Norwegian Adults Aged 50 Years and Older: Cross-Sectional PROTECT Norge Study","title_match":false,"year":2025},{"alzhub_score":50,"alzhub_url":"https://alzhub.org/study/the-impact-of-presentation-modality-on-cognitive-test-performance-for-34971091","doi":"10.1002/alz.058571","journal":"Alzheimer's & dementia : the journal of the Alzheimer's Association","n_participants":63,"pmid":"34971091","source_url":"https://pubmed.ncbi.nlm.nih.gov/34971091/","study_design":null,"title":"The impact of presentation modality on cognitive test performance for adults with hearing loss","title_match":true,"year":2021}]}