{"data_date":"2026-11-09","library_size":29780,"matched_against":"each record's title and abstract (summary field), case-insensitive","n":448,"page":"https://alzhub.org/answers/alcohol-and-dementia","query":"title or abstract mentions \"alcohol\", \"drinking\", \"drinkers\", \"wine\", \"ethanol\" or \"binge\"","studies":[{"alzhub_score":65,"alzhub_url":"https://alzhub.org/study/alcohol-consumption-and-risk-of-dementia-23-year-follow-up-of-b8c2bc18","doi":null,"journal":"BMJ","n_participants":9087,"pmid":null,"source_url":"https://www.bmj.com/content/362/bmj.k2927","study_design":"cohort","title":"Alcohol consumption and risk of dementia: 23 year follow-up of Whitehall II cohort study","title_match":true,"year":2018},{"alzhub_score":61,"alzhub_url":"https://alzhub.org/study/risk-of-dementia-in-individuals-with-emergency-department-visits-or-40227745","doi":"10.1001/jamaneurol.2025.0530","journal":"JAMA Neurology","n_participants":6086794,"pmid":"40227745","source_url":"https://pubmed.ncbi.nlm.nih.gov/40227745/","study_design":"cohort","title":"Risk of Dementia in Individuals With Emergency Department Visits or Hospitalizations Due to Cannabis","title_match":false,"year":2025},{"alzhub_score":72,"alzhub_url":"https://alzhub.org/study/risk-factors-for-young-onset-dementia-in-the-uk-biobank-38147328","doi":"10.1001/jamaneurol.2023.4929","journal":"JAMA Neurology","n_participants":356052,"pmid":"38147328","source_url":"https://pubmed.ncbi.nlm.nih.gov/38147328/","study_design":"cohort","title":"Risk Factors for Young-Onset Dementia in the UK Biobank","title_match":false,"year":2024},{"alzhub_score":58,"alzhub_url":"https://alzhub.org/study/prioritizing-modifiable-risk-factors-for-dementia-prevention-across-41085200","doi":"10.1002/ana.78060","journal":"Annals of Neurology","n_participants":182473,"pmid":"41085200","source_url":"https://pubmed.ncbi.nlm.nih.gov/41085200/","study_design":"cohort","title":"Prioritizing Modifiable Risk Factors for Dementia Prevention across the Spectrum of Genetic Susceptibility: A Prospective Cohort Study","title_match":false,"year":2025},{"alzhub_score":68,"alzhub_url":"https://alzhub.org/study/alcohol-use-and-risk-of-dementia-in-diverse-populations-evidence-from-40987604","doi":"10.1136/bmjebm-2025-113913","journal":"BMJ Evidence-Based Medicine","n_participants":559559,"pmid":"40987604","source_url":"https://pubmed.ncbi.nlm.nih.gov/40987604/","study_design":"cohort","title":"Alcohol use and risk of dementia in diverse populations: evidence from cohort, case-control and Mendelian randomisation approaches","title_match":true,"year":2026},{"alzhub_score":73,"alzhub_url":"https://alzhub.org/study/changes-in-alcohol-consumption-and-risk-of-dementia-in-a-nationwide-36745453","doi":"10.1001/jamanetworkopen.2022.54771","journal":"JAMA Network Open","n_participants":3933382,"pmid":"36745453","source_url":"https://pubmed.ncbi.nlm.nih.gov/36745453/","study_design":"cohort","title":"Changes in Alcohol Consumption and Risk of Dementia in a Nationwide Cohort in South Korea","title_match":true,"year":2023},{"alzhub_score":52,"alzhub_url":"https://alzhub.org/study/associations-of-alcohol-drinking-with-incident-dementia-a-prospective-41014391","doi":"10.1007/s10654-025-01304-y","journal":"European Journal of Epidemiology","n_participants":296715,"pmid":"41014391","source_url":"https://pubmed.ncbi.nlm.nih.gov/41014391/","study_design":"cohort","title":"Associations of alcohol drinking with incident dementia: a prospective study from the UK Biobank","title_match":true,"year":2025},{"alzhub_score":66,"alzhub_url":"https://alzhub.org/study/flavonoid-rich-foods-dementia-risk-and-interactions-with-genetic-risk-39292460","doi":"10.1001/jamanetworkopen.2024.34136","journal":"JAMA Network Open","n_participants":121986,"pmid":"39292460","source_url":"https://pubmed.ncbi.nlm.nih.gov/39292460/","study_design":"cohort","title":"Flavonoid-Rich Foods, Dementia Risk, and Interactions With Genetic Risk, Hypertension, and Depression","title_match":false,"year":2024},{"alzhub_score":65,"alzhub_url":"https://alzhub.org/study/risk-factors-for-early-onset-and-late-onset-dementia-a-prospective-41936382","doi":"10.1016/j.lanhl.2026.100831","journal":"The lancet. Healthy longevity","n_participants":544442,"pmid":"41936382","source_url":"https://pubmed.ncbi.nlm.nih.gov/41936382/","study_design":"cohort","title":"Risk factors for early-onset and late-onset dementia: a prospective cohort study","title_match":false,"year":2026},{"alzhub_score":47,"alzhub_url":"https://alzhub.org/study/inhibitory-effect-of-4-o-methylhonokiol-on-lipopolysaccharide-induced-22339795","doi":"10.1186/1742-2094-9-35","journal":"Journal of neuroinflammation","n_participants":null,"pmid":"22339795","source_url":"https://pubmed.ncbi.nlm.nih.gov/22339795/","study_design":null,"title":"Inhibitory effect of 4-O-methylhonokiol on lipopolysaccharide-induced neuroinflammation, amyloidogenesis and memory impairment via inhibition of nuclear factor-kappaB in vitro and in vivo models","title_match":false,"year":2012},{"alzhub_score":39,"alzhub_url":"https://alzhub.org/study/methylene-blue-inhibits-caspase-6-activity-and-reverses-caspase-6-31843022","doi":"10.1186/s40478-019-0856-6","journal":"Acta neuropathologica communications","n_participants":null,"pmid":"31843022","source_url":"https://pubmed.ncbi.nlm.nih.gov/31843022/","study_design":null,"title":"Methylene blue inhibits Caspase-6 activity, and reverses Caspase-6-induced cognitive impairment and neuroinflammation in aged mice","title_match":false,"year":2019},{"alzhub_score":56,"alzhub_url":"https://alzhub.org/study/nonalcoholic-fatty-liver-disease-and-longitudinal-change-in-imaging-38471046","doi":"10.1212/wnl.0000000000209203","journal":"Neurology","n_participants":1706,"pmid":"38471046","source_url":"https://pubmed.ncbi.nlm.nih.gov/38471046/","study_design":null,"title":"Nonalcoholic Fatty Liver Disease and Longitudinal Change in Imaging and Plasma Biomarkers of Alzheimer Disease and Vascular Pathology","title_match":false,"year":2024},{"alzhub_score":37,"alzhub_url":"https://alzhub.org/study/in-vivo-demonstration-of-congo-red-labeled-amyloid-plaques-via-33508413","doi":"10.1016/j.jneumeth.2021.109082","journal":"Journal of neuroscience methods","n_participants":null,"pmid":"33508413","source_url":"https://pubmed.ncbi.nlm.nih.gov/33508413/","study_design":null,"title":"In vivo demonstration of Congo Red labeled amyloid plaques via perfusion in the Alzheimer disease rat model","title_match":false,"year":2021},{"alzhub_score":60,"alzhub_url":"https://alzhub.org/study/cardiovascular-risk-factors-and-incident-alzheimer-disease-a-18703981","doi":"10.1097/wad.0b013e318187541c","journal":"Alzheimer disease and associated disorders","n_participants":null,"pmid":"18703981","source_url":"https://pubmed.ncbi.nlm.nih.gov/18703981/","study_design":"systematic review","title":"Cardiovascular risk factors and incident Alzheimer disease: a systematic review of the literature","title_match":false,"year":2009},{"alzhub_score":43,"alzhub_url":"https://alzhub.org/study/environment-and-gene-association-with-obesity-and-their-impact-on-32982666","doi":"10.3389/fnins.2020.00863","journal":"Frontiers in neuroscience","n_participants":null,"pmid":"32982666","source_url":"https://pubmed.ncbi.nlm.nih.gov/32982666/","study_design":null,"title":"Environment and Gene Association With Obesity and Their Impact on Neurodegenerative and Neurodevelopmental Diseases","title_match":false,"year":2020},{"alzhub_score":65,"alzhub_url":"https://alzhub.org/study/association-of-apoe-4-genotype-and-lifestyle-with-cognitive-function-34061824","doi":"10.1371/journal.pmed.1003597","journal":"PLoS medicine","n_participants":null,"pmid":"34061824","source_url":"https://pubmed.ncbi.nlm.nih.gov/34061824/","study_design":"cohort study","title":"Association of APOE \u03b54 genotype and lifestyle with cognitive function among Chinese adults aged 80 years and older: A cross-sectional study","title_match":false,"year":2021},{"alzhub_score":39,"alzhub_url":"https://alzhub.org/study/processing-of-the-synaptic-cell-adhesion-molecule-neurexin-3beta-by-21084300","doi":"10.1074/jbc.m110.142521","journal":"The Journal of biological chemistry","n_participants":null,"pmid":"21084300","source_url":"https://pubmed.ncbi.nlm.nih.gov/21084300/","study_design":null,"title":"Processing of the synaptic cell adhesion molecule neurexin-3beta by Alzheimer disease alpha- and gamma-secretases","title_match":false,"year":2011},{"alzhub_score":57,"alzhub_url":"https://alzhub.org/study/a-phase-i-study-to-assess-the-effect-of-speed-of-injection-on-pain-31883703","doi":"10.1016/j.clinthera.2019.11.015","journal":"Clinical therapeutics","n_participants":null,"pmid":"31883703","source_url":"https://pubmed.ncbi.nlm.nih.gov/31883703/","study_design":"open-label trial","title":"A Phase I Study to Assess the Effect of Speed of Injection on Pain, Tolerability, and Pharmacokinetics After High-volume Subcutaneous Administration of Gantenerumab in Healthy Volunteers","title_match":false,"year":2020},{"alzhub_score":69,"alzhub_url":"https://alzhub.org/study/aluminium-and-the-pathogenesis-of-alzheimer-s-disease-a-summary-of-1490430","doi":"10.1002/9780470514306.ch6","journal":"Ciba Foundation symposium","n_participants":null,"pmid":"1490430","source_url":"https://pubmed.ncbi.nlm.nih.gov/1490430/","study_design":"randomized controlled trial","title":"Aluminium and the pathogenesis of Alzheimer's disease: a summary of evidence","title_match":false,"year":1992},{"alzhub_score":59,"alzhub_url":"https://alzhub.org/study/assessing-the-effectiveness-of-ehealth-interventions-to-manage-39083787","doi":"10.2196/58174","journal":"Journal of medical Internet research","n_participants":34,"pmid":"39083787","source_url":"https://pubmed.ncbi.nlm.nih.gov/39083787/","study_design":null,"title":"Assessing the Effectiveness of eHealth Interventions to Manage Multiple Lifestyle Risk Behaviors Among Older Adults: Systematic Review and Meta-Analysis","title_match":false,"year":2024},{"alzhub_score":56,"alzhub_url":"https://alzhub.org/study/thiamine-for-alzheimer-s-disease-11405995","doi":"10.1002/14651858.cd001498","journal":"The Cochrane database of systematic reviews","n_participants":null,"pmid":"11405995","source_url":"https://pubmed.ncbi.nlm.nih.gov/11405995/","study_design":"systematic review","title":"Thiamine for Alzheimer's disease","title_match":false,"year":2001},{"alzhub_score":54,"alzhub_url":"https://alzhub.org/study/mechanisms-pathophysiology-and-therapy-of-arterial-stiffness-15731494","doi":"10.1161/01.atv.0000160548.78317.29","journal":"Arteriosclerosis, thrombosis, and vascular biology","n_participants":null,"pmid":"15731494","source_url":"https://pubmed.ncbi.nlm.nih.gov/15731494/","study_design":null,"title":"Mechanisms, pathophysiology, and therapy of arterial stiffness","title_match":false,"year":2005},{"alzhub_score":46,"alzhub_url":"https://alzhub.org/study/ageing-and-the-brain-16461469","doi":"10.1136/pgmj.2005.036665","journal":"Postgraduate medical journal","n_participants":null,"pmid":"16461469","source_url":"https://pubmed.ncbi.nlm.nih.gov/16461469/","study_design":null,"title":"Ageing and the brain","title_match":false,"year":2006},{"alzhub_score":78,"alzhub_url":"https://alzhub.org/study/mediterranean-diet-improves-cognition-the-predimed-navarra-randomised-23670794","doi":"10.1136/jnnp-2012-304792","journal":"Journal of neurology, neurosurgery, and psychiatry","n_participants":522,"pmid":"23670794","source_url":"https://pubmed.ncbi.nlm.nih.gov/23670794/","study_design":null,"title":"Mediterranean diet improves cognition: the PREDIMED-NAVARRA randomised trial","title_match":false,"year":2013},{"alzhub_score":53,"alzhub_url":"https://alzhub.org/study/considering-sex-and-gender-in-alzheimer-disease-and-other-dementias-28179815","doi":"10.31887/dcns.2016.18.4/cepperson","journal":"Dialogues in clinical neuroscience","n_participants":null,"pmid":"28179815","source_url":"https://pubmed.ncbi.nlm.nih.gov/28179815/","study_design":null,"title":"Considering sex and gender in Alzheimer disease and other dementias","title_match":false,"year":2016},{"alzhub_score":57,"alzhub_url":"https://alzhub.org/study/nutrition-and-prevention-of-cognitive-impairment-30244829","doi":"10.1016/s1474-4422(18)30338-7","journal":"The Lancet. Neurology","n_participants":null,"pmid":"30244829","source_url":"https://pubmed.ncbi.nlm.nih.gov/30244829/","study_design":null,"title":"Nutrition and prevention of cognitive impairment","title_match":false,"year":2018},{"alzhub_score":52,"alzhub_url":"https://alzhub.org/study/risk-factors-for-community-acquired-pneumonia-in-adults-in-europe-a-24130229","doi":"10.1136/thoraxjnl-2013-204282","journal":"Thorax","n_participants":null,"pmid":"24130229","source_url":"https://pubmed.ncbi.nlm.nih.gov/24130229/","study_design":null,"title":"Risk factors for community-acquired pneumonia in adults in Europe: a literature review","title_match":false,"year":2013},{"alzhub_score":51,"alzhub_url":"https://alzhub.org/study/fruit-and-vegetable-juices-and-alzheimer-s-disease-the-kame-project-16945610","doi":"10.1016/j.amjmed.2006.03.045","journal":"The American journal of medicine","n_participants":null,"pmid":"16945610","source_url":"https://pubmed.ncbi.nlm.nih.gov/16945610/","study_design":null,"title":"Fruit and vegetable juices and Alzheimer's disease: the Kame Project","title_match":false,"year":2006},{"alzhub_score":46,"alzhub_url":"https://alzhub.org/study/statin-therapy-review-of-safety-and-potential-side-effects-27899849","doi":"10.6515/acs20160611a","journal":"Acta Cardiologica Sinica","n_participants":null,"pmid":"27899849","source_url":"https://pubmed.ncbi.nlm.nih.gov/27899849/","study_design":null,"title":"Statin Therapy: Review of Safety and Potential Side Effects","title_match":false,"year":2016},{"alzhub_score":67,"alzhub_url":"https://alzhub.org/study/risk-factors-associated-with-the-onset-and-progression-of-alzheimer-s-28363508","doi":"10.1016/j.neuro.2017.03.006","journal":"Neurotoxicology","n_participants":65,"pmid":"28363508","source_url":"https://pubmed.ncbi.nlm.nih.gov/28363508/","study_design":"systematic review","title":"Risk factors associated with the onset and progression of Alzheimer's disease: A systematic review of the evidence","title_match":false,"year":2017},{"alzhub_score":54,"alzhub_url":"https://alzhub.org/study/midlife-coffee-and-tea-drinking-and-the-risk-of-late-life-dementia-a-19158424","doi":"10.3233/jad-2009-0920","journal":"Journal of Alzheimer's disease : JAD","n_participants":1409,"pmid":"19158424","source_url":"https://pubmed.ncbi.nlm.nih.gov/19158424/","study_design":null,"title":"Midlife coffee and tea drinking and the risk of late-life dementia: a population-based CAIDE study","title_match":true,"year":2009},{"alzhub_score":52,"alzhub_url":"https://alzhub.org/study/alcohol-use-and-dementia-a-systematic-scoping-review-30611304","doi":"10.1186/s13195-018-0453-0","journal":"Alzheimer's research & therapy","n_participants":null,"pmid":"30611304","source_url":"https://pubmed.ncbi.nlm.nih.gov/30611304/","study_design":null,"title":"Alcohol use and dementia: a systematic scoping review","title_match":true,"year":2019},{"alzhub_score":58,"alzhub_url":"https://alzhub.org/study/potentially-modifiable-lifestyle-factors-cognitive-reserve-and-28323829","doi":"10.1371/journal.pmed.1002259","journal":"PLoS medicine","n_participants":null,"pmid":"28323829","source_url":"https://pubmed.ncbi.nlm.nih.gov/28323829/","study_design":"cross-sectional","title":"Potentially modifiable lifestyle factors, cognitive reserve, and cognitive function in later life: A cross-sectional study","title_match":false,"year":2017},{"alzhub_score":53,"alzhub_url":"https://alzhub.org/study/wine-consumption-and-dementia-in-the-elderly-a-prospective-community-9296132","doi":null,"journal":"Revue neurologique","n_participants":3777,"pmid":"9296132","source_url":"https://pubmed.ncbi.nlm.nih.gov/9296132/","study_design":null,"title":"Wine consumption and dementia in the elderly: a prospective community study in the Bordeaux area","title_match":true,"year":1997},{"alzhub_score":47,"alzhub_url":"https://alzhub.org/study/cardiovascular-disease-and-alzheimer-s-disease-common-links-16918818","doi":"10.1111/j.1365-2796.2006.01687.x","journal":"Journal of internal medicine","n_participants":null,"pmid":"16918818","source_url":"https://pubmed.ncbi.nlm.nih.gov/16918818/","study_design":null,"title":"Cardiovascular disease and Alzheimer's disease: common links","title_match":false,"year":2006},{"alzhub_score":45,"alzhub_url":"https://alzhub.org/study/risk-factors-for-hip-fracture-in-men-from-southern-europe-the-medos-10367029","doi":"10.1007/s001980050115","journal":"Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA","n_participants":null,"pmid":"10367029","source_url":"https://pubmed.ncbi.nlm.nih.gov/10367029/","study_design":null,"title":"Risk factors for hip fracture in men from southern Europe: the MEDOS study. Mediterranean Osteoporosis Study","title_match":false,"year":1999},{"alzhub_score":55,"alzhub_url":"https://alzhub.org/study/does-caffeine-intake-protect-from-alzheimer-s-disease-12099922","doi":"10.1046/j.1468-1331.2002.00421.x","journal":"European journal of neurology","n_participants":54,"pmid":"12099922","source_url":"https://pubmed.ncbi.nlm.nih.gov/12099922/","study_design":"case-control study","title":"Does caffeine intake protect from Alzheimer's disease?","title_match":false,"year":2002},{"alzhub_score":64,"alzhub_url":"https://alzhub.org/study/predictors-of-functional-change-a-longitudinal-study-of-nondemented-12383150","doi":"10.1046/j.1532-5415.2002.50408.x","journal":"Journal of the American Geriatrics Society","n_participants":null,"pmid":"12383150","source_url":"https://pubmed.ncbi.nlm.nih.gov/12383150/","study_design":"cohort study","title":"Predictors of functional change: a longitudinal study of nondemented people aged 65 and older","title_match":false,"year":2002},{"alzhub_score":58,"alzhub_url":"https://alzhub.org/study/apolipoprotein-e-epsilon4-magnifies-lifestyle-risks-for-dementia-a-18318693","doi":"10.1111/j.1582-4934.2008.00296.x","journal":"Journal of cellular and molecular medicine","n_participants":1449,"pmid":"18318693","source_url":"https://pubmed.ncbi.nlm.nih.gov/18318693/","study_design":null,"title":"Apolipoprotein E epsilon4 magnifies lifestyle risks for dementia: a population-based study","title_match":false,"year":2008},{"alzhub_score":74,"alzhub_url":"https://alzhub.org/study/virgin-olive-oil-supplementation-and-long-term-cognition-the-predimed-23732551","doi":"10.1007/s12603-013-0027-6","journal":"The journal of nutrition, health & aging","n_participants":285,"pmid":"23732551","source_url":"https://pubmed.ncbi.nlm.nih.gov/23732551/","study_design":"randomized controlled trial","title":"Virgin olive oil supplementation and long-term cognition: the PREDIMED-NAVARRA randomized, trial","title_match":false,"year":2013},{"alzhub_score":44,"alzhub_url":"https://alzhub.org/study/vascular-basis-for-brain-degeneration-faltering-controls-and-risk-21091952","doi":"10.1111/j.1753-4887.2010.00352.x","journal":"Nutrition reviews","n_participants":null,"pmid":"21091952","source_url":"https://pubmed.ncbi.nlm.nih.gov/21091952/","study_design":null,"title":"Vascular basis for brain degeneration: faltering controls and risk factors for dementia","title_match":false,"year":2010},{"alzhub_score":50,"alzhub_url":"https://alzhub.org/study/prevention-of-diseases-after-menopause-24969415","doi":"10.3109/13697137.2014.933411","journal":"Climacteric : the journal of the International Menopause Society","n_participants":null,"pmid":"24969415","source_url":"https://pubmed.ncbi.nlm.nih.gov/24969415/","study_design":null,"title":"Prevention of diseases after menopause","title_match":false,"year":2014},{"alzhub_score":59,"alzhub_url":"https://alzhub.org/study/association-between-self-reported-dental-health-status-and-onset-of-22408130","doi":"10.1097/psy.0b013e318246dffb","journal":"Psychosomatic medicine","n_participants":220,"pmid":"22408130","source_url":"https://pubmed.ncbi.nlm.nih.gov/22408130/","study_design":"cohort study","title":"Association between self-reported dental health status and onset of dementia: a 4-year prospective cohort study of older Japanese adults from the Aichi Gerontological Evaluation Study (AGES) Project","title_match":false,"year":2012},{"alzhub_score":77,"alzhub_url":"https://alzhub.org/study/healthy-lifestyle-and-the-risk-of-alzheimer-dementia-findings-from-2-32554763","doi":"10.1212/wnl.0000000000009816","journal":"Neurology","n_participants":1845,"pmid":"32554763","source_url":"https://pubmed.ncbi.nlm.nih.gov/32554763/","study_design":"meta-analysis","title":"Healthy lifestyle and the risk of Alzheimer dementia: Findings from 2 longitudinal studies","title_match":false,"year":2020},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/diet-and-alzheimer-s-disease-risk-factors-or-prevention-the-current-21539488","doi":"10.1586/ern.11.56","journal":"Expert review of neurotherapeutics","n_participants":null,"pmid":"21539488","source_url":"https://pubmed.ncbi.nlm.nih.gov/21539488/","study_design":null,"title":"Diet and Alzheimer's disease risk factors or prevention: the current evidence","title_match":false,"year":2011},{"alzhub_score":58,"alzhub_url":"https://alzhub.org/study/systematic-review-of-health-behavioral-risks-and-cognitive-health-in-19883522","doi":"10.1017/s1041610209991189","journal":"International psychogeriatrics","n_participants":null,"pmid":"19883522","source_url":"https://pubmed.ncbi.nlm.nih.gov/19883522/","study_design":"systematic review","title":"Systematic review of health behavioral risks and cognitive health in older adults","title_match":false,"year":2010},{"alzhub_score":48,"alzhub_url":"https://alzhub.org/study/alcohol-related-dementia-an-update-of-the-evidence-23347747","doi":"10.1186/alzrt157","journal":"Alzheimer's research & therapy","n_participants":null,"pmid":"23347747","source_url":"https://pubmed.ncbi.nlm.nih.gov/23347747/","study_design":null,"title":"Alcohol-related dementia: an update of the evidence","title_match":true,"year":2013},{"alzhub_score":61,"alzhub_url":"https://alzhub.org/study/physical-exercise-at-midlife-and-risk-of-dementia-three-decades-later-18245762","doi":"10.1093/gerona/63.1.62","journal":"The journals of gerontology. Series A, Biological sciences and medical sciences","n_participants":264,"pmid":"18245762","source_url":"https://pubmed.ncbi.nlm.nih.gov/18245762/","study_design":"case-control study","title":"Physical exercise at midlife and risk of dementia three decades later: a population-based study of Swedish twins","title_match":false,"year":2008},{"alzhub_score":57,"alzhub_url":"https://alzhub.org/study/predicting-risk-of-dementia-in-older-adults-the-late-life-dementia-19439724","doi":"10.1212/wnl.0b013e3181a81636","journal":"Neurology","n_participants":480,"pmid":"19439724","source_url":"https://pubmed.ncbi.nlm.nih.gov/19439724/","study_design":null,"title":"Predicting risk of dementia in older adults: The late-life dementia risk index","title_match":false,"year":2009},{"alzhub_score":54,"alzhub_url":"https://alzhub.org/study/economic-hardship-and-biological-weathering-the-epigenetics-of-aging-26765221","doi":"10.1016/j.socscimed.2015.12.001","journal":"Social science & medicine (1982)","n_participants":null,"pmid":"26765221","source_url":"https://pubmed.ncbi.nlm.nih.gov/26765221/","study_design":"longitudinal study","title":"Economic hardship and biological weathering: The epigenetics of aging in a U.S. sample of black women","title_match":false,"year":2016},{"alzhub_score":65,"alzhub_url":"https://alzhub.org/study/dietary-patterns-and-risk-of-dementia-a-systematic-review-and-meta-26553347","doi":"10.1007/s12035-015-9516-4","journal":"Molecular neurobiology","n_participants":null,"pmid":"26553347","source_url":"https://pubmed.ncbi.nlm.nih.gov/26553347/","study_design":"meta-analysis","title":"Dietary Patterns and Risk of Dementia: a Systematic Review and Meta-Analysis of Cohort Studies","title_match":false,"year":2016},{"alzhub_score":50,"alzhub_url":"https://alzhub.org/study/warfarin-use-among-patients-with-atrial-fibrillation-9412618","doi":"10.1161/01.str.28.12.2382","journal":"Stroke","n_participants":488,"pmid":"9412618","source_url":"https://pubmed.ncbi.nlm.nih.gov/9412618/","study_design":null,"title":"Warfarin use among patients with atrial fibrillation","title_match":false,"year":1997},{"alzhub_score":45,"alzhub_url":"https://alzhub.org/study/phenotypes-of-prediabetes-and-stratification-of-cardiometabolic-risk-27185609","doi":"10.1016/s2213-8587(16)00082-6","journal":"The lancet. Diabetes & endocrinology","n_participants":null,"pmid":"27185609","source_url":"https://pubmed.ncbi.nlm.nih.gov/27185609/","study_design":null,"title":"Phenotypes of prediabetes and stratification of cardiometabolic risk","title_match":false,"year":2016},{"alzhub_score":53,"alzhub_url":"https://alzhub.org/study/caffeine-as-a-protective-factor-in-dementia-and-alzheimer-s-disease-20182054","doi":"10.3233/jad-2010-1404","journal":"Journal of Alzheimer's disease : JAD","n_participants":null,"pmid":"20182054","source_url":"https://pubmed.ncbi.nlm.nih.gov/20182054/","study_design":"longitudinal study","title":"Caffeine as a protective factor in dementia and Alzheimer's disease","title_match":false,"year":2010},{"alzhub_score":64,"alzhub_url":"https://alzhub.org/study/vascular-dementia-incidence-and-risk-factors-in-the-canadian-study-of-10884442","doi":"10.1161/01.str.31.7.1487","journal":"Stroke","n_participants":8623,"pmid":"10884442","source_url":"https://pubmed.ncbi.nlm.nih.gov/10884442/","study_design":"case-control study","title":"Vascular dementia : incidence and risk factors in the Canadian study of health and aging","title_match":false,"year":2000},{"alzhub_score":66,"alzhub_url":"https://alzhub.org/study/estrogen-replacement-therapy-and-alzheimer-s-disease-in-the-italian-9566385","doi":"10.1212/wnl.50.4.996","journal":"Neurology","n_participants":null,"pmid":"9566385","source_url":"https://pubmed.ncbi.nlm.nih.gov/9566385/","study_design":null,"title":"Estrogen-replacement therapy and Alzheimer's disease in the Italian Longitudinal Study on Aging","title_match":false,"year":1998},{"alzhub_score":50,"alzhub_url":"https://alzhub.org/study/nutrition-and-cognitive-health-a-life-course-approach-37050953","doi":"10.3389/fpubh.2023.1023907","journal":"Frontiers in public health","n_participants":null,"pmid":"37050953","source_url":"https://pubmed.ncbi.nlm.nih.gov/37050953/","study_design":null,"title":"Nutrition and cognitive health: A life course approach","title_match":false,"year":2023},{"alzhub_score":54,"alzhub_url":"https://alzhub.org/study/a-nationwide-survey-on-the-prevalence-of-dementia-and-mild-cognitive-21178286","doi":"10.3233/jad-2010-101221","journal":"Journal of Alzheimer's disease : JAD","n_participants":6141,"pmid":"21178286","source_url":"https://pubmed.ncbi.nlm.nih.gov/21178286/","study_design":null,"title":"A nationwide survey on the prevalence of dementia and mild cognitive impairment in South Korea","title_match":false,"year":2011},{"alzhub_score":44,"alzhub_url":"https://alzhub.org/study/the-epidemiology-of-common-late-life-mental-disorders-in-the-10478901","doi":"10.1176/ps.50.9.1158","journal":"Psychiatric services (Washington, D.C.)","n_participants":null,"pmid":"10478901","source_url":"https://pubmed.ncbi.nlm.nih.gov/10478901/","study_design":null,"title":"The epidemiology of common late-life mental disorders in the community: themes for the new century","title_match":false,"year":1999},{"alzhub_score":66,"alzhub_url":"https://alzhub.org/study/consumption-of-coffee-and-tea-and-risk-of-developing-stroke-dementia-34784347","doi":"10.1371/journal.pmed.1003830","journal":"PLoS medicine","n_participants":365682,"pmid":"34784347","source_url":"https://pubmed.ncbi.nlm.nih.gov/34784347/","study_design":"cohort study","title":"Consumption of coffee and tea and risk of developing stroke, dementia, and poststroke dementia: A cohort study in the UK Biobank","title_match":false,"year":2021},{"alzhub_score":56,"alzhub_url":"https://alzhub.org/study/mild-cognitive-impairment-and-dementia-the-importance-of-modifiable-22163250","doi":"10.3238/arztebl.2011.0743","journal":"Deutsches Arzteblatt international","n_participants":null,"pmid":"22163250","source_url":"https://pubmed.ncbi.nlm.nih.gov/22163250/","study_design":null,"title":"Mild cognitive impairment and dementia: the importance of modifiable risk factors","title_match":false,"year":2011},{"alzhub_score":65,"alzhub_url":"https://alzhub.org/study/association-between-midlife-risk-factors-and-late-onset-epilepsy-30039175","doi":"10.1001/jamaneurol.2018.1935","journal":"JAMA neurology","n_participants":792,"pmid":"30039175","source_url":"https://pubmed.ncbi.nlm.nih.gov/30039175/","study_design":"cohort study","title":"Association Between Midlife Risk Factors and Late-Onset Epilepsy: Results From the Atherosclerosis Risk in Communities Study","title_match":false,"year":2018},{"alzhub_score":69,"alzhub_url":"https://alzhub.org/study/how-can-dementia-and-disability-be-prevented-in-older-adults-where-33314384","doi":"10.1111/joim.13227","journal":"Journal of internal medicine","n_participants":null,"pmid":"33314384","source_url":"https://pubmed.ncbi.nlm.nih.gov/33314384/","study_design":"randomized controlled trial","title":"How can dementia and disability be prevented in older adults: where are we today and where are we going?","title_match":false,"year":2021},{"alzhub_score":56,"alzhub_url":"https://alzhub.org/study/modifiable-risk-factors-for-prevention-of-dementia-in-midlife-late-28453475","doi":"10.3233/jad-161208","journal":"Journal of Alzheimer's disease : JAD","n_participants":3256,"pmid":"28453475","source_url":"https://pubmed.ncbi.nlm.nih.gov/28453475/","study_design":null,"title":"Modifiable Risk Factors for Prevention of\u00a0Dementia in Midlife, Late Life and the Oldest-Old: Validation of the LIBRA Index","title_match":false,"year":2017},{"alzhub_score":65,"alzhub_url":"https://alzhub.org/study/modifiable-lifestyle-factors-in-dementia-a-systematic-review-of-24799342","doi":"10.3233/jad-132225","journal":"Journal of Alzheimer's disease : JAD","n_participants":26,"pmid":"24799342","source_url":"https://pubmed.ncbi.nlm.nih.gov/24799342/","study_design":"systematic review","title":"Modifiable lifestyle factors in dementia: a systematic review of longitudinal observational cohort studies","title_match":false,"year":2014},{"alzhub_score":62,"alzhub_url":"https://alzhub.org/study/behavioural-risk-factors-in-mid-life-associated-with-successful-26845035","doi":"10.1371/journal.pone.0144405","journal":"PloS one","n_participants":null,"pmid":"26845035","source_url":"https://pubmed.ncbi.nlm.nih.gov/26845035/","study_design":"cohort study","title":"Behavioural Risk Factors in Mid-Life Associated with Successful Ageing, Disability, Dementia and Frailty in Later Life: A Rapid Systematic Review","title_match":false,"year":2016},{"alzhub_score":61,"alzhub_url":"https://alzhub.org/study/promoting-successful-cognitive-aging-a-ten-year-update-33935078","doi":"10.3233/jad-201462","journal":"Journal of Alzheimer's disease : JAD","n_participants":null,"pmid":"33935078","source_url":"https://pubmed.ncbi.nlm.nih.gov/33935078/","study_design":"cohort study","title":"Promoting Successful Cognitive Aging: A Ten-Year Update","title_match":false,"year":2021},{"alzhub_score":43,"alzhub_url":"https://alzhub.org/study/vegetables-unsaturated-fats-moderate-alcohol-intake-and-mild-20502015","doi":"10.1159/000305099","journal":"Dementia and geriatric cognitive disorders","n_participants":null,"pmid":"20502015","source_url":"https://pubmed.ncbi.nlm.nih.gov/20502015/","study_design":null,"title":"Vegetables, unsaturated fats, moderate alcohol intake, and mild cognitive impairment","title_match":true,"year":2010},{"alzhub_score":77,"alzhub_url":"https://alzhub.org/study/determinants-of-cognitive-performance-and-decline-in-20-diverse-ethno-31335910","doi":"10.1371/journal.pmed.1002853","journal":"PLoS medicine","n_participants":48522,"pmid":"31335910","source_url":"https://pubmed.ncbi.nlm.nih.gov/31335910/","study_design":"meta-analysis","title":"Determinants of cognitive performance and decline in 20 diverse ethno-regional groups: A COSMIC collaboration cohort study","title_match":false,"year":2019},{"alzhub_score":64,"alzhub_url":"https://alzhub.org/study/adherence-to-the-2015-dutch-dietary-guidelines-and-risk-of-non-28825166","doi":"10.1007/s10654-017-0295-2","journal":"European journal of epidemiology","n_participants":9701,"pmid":"28825166","source_url":"https://pubmed.ncbi.nlm.nih.gov/28825166/","study_design":"prospective cohort","title":"Adherence to the 2015 Dutch dietary guidelines and risk of non-communicable diseases and mortality in the Rotterdam Study","title_match":false,"year":2017},{"alzhub_score":61,"alzhub_url":"https://alzhub.org/study/obesity-in-middle-age-and-future-risk-of-dementia-a-27-year-15863436","doi":"10.1136/bmj.38446.466238.e0","journal":"BMJ (Clinical research ed.)","n_participants":null,"pmid":"15863436","source_url":"https://pubmed.ncbi.nlm.nih.gov/15863436/","study_design":null,"title":"Obesity in middle age and future risk of dementia: a 27 year longitudinal population based study","title_match":false,"year":2005},{"alzhub_score":56,"alzhub_url":"https://alzhub.org/study/classifying-neurocognitive-disorders-the-dsm-5-approach-25266297","doi":"10.1038/nrneurol.2014.181","journal":"Nature reviews. Neurology","n_participants":null,"pmid":"25266297","source_url":"https://pubmed.ncbi.nlm.nih.gov/25266297/","study_design":null,"title":"Classifying neurocognitive disorders: the DSM-5 approach","title_match":false,"year":2014},{"alzhub_score":56,"alzhub_url":"https://alzhub.org/study/incidence-and-risk-factors-of-vascular-dementia-and-alzheimer-s-7783883","doi":"10.1212/wnl.45.6.1161","journal":"Neurology","n_participants":103,"pmid":"7783883","source_url":"https://pubmed.ncbi.nlm.nih.gov/7783883/","study_design":null,"title":"Incidence and risk factors of vascular dementia and Alzheimer's disease in a defined elderly Japanese population: the Hisayama Study","title_match":false,"year":1995},{"alzhub_score":53,"alzhub_url":"https://alzhub.org/study/lower-cognitive-function-in-the-presence-of-obesity-and-hypertension-12587008","doi":"10.1038/sj.ijo.802225","journal":"International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity","n_participants":551,"pmid":"12587008","source_url":"https://pubmed.ncbi.nlm.nih.gov/12587008/","study_design":null,"title":"Lower cognitive function in the presence of obesity and hypertension: the Framingham heart study","title_match":false,"year":2003},{"alzhub_score":46,"alzhub_url":"https://alzhub.org/study/cerebrospinal-fluid-protein-biomarkers-for-alzheimer-s-disease-15717022","doi":"10.1602/neurorx.1.2.213","journal":"NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics","n_participants":null,"pmid":"15717022","source_url":"https://pubmed.ncbi.nlm.nih.gov/15717022/","study_design":null,"title":"Cerebrospinal fluid protein biomarkers for Alzheimer's disease","title_match":false,"year":2004},{"alzhub_score":46,"alzhub_url":"https://alzhub.org/study/postoperative-cognitive-dysfunction-24622758","doi":"10.3238/arztebl.2014.0119","journal":"Deutsches Arzteblatt international","n_participants":null,"pmid":"24622758","source_url":"https://pubmed.ncbi.nlm.nih.gov/24622758/","study_design":null,"title":"Postoperative cognitive dysfunction","title_match":false,"year":2014},{"alzhub_score":59,"alzhub_url":"https://alzhub.org/study/prevalence-of-dementia-subtypes-in-united-states-medicare-fee-for-27172148","doi":"10.1016/j.jalz.2016.04.002","journal":"Alzheimer's & dementia : the journal of the Alzheimer's Association","n_participants":21,"pmid":"27172148","source_url":"https://pubmed.ncbi.nlm.nih.gov/27172148/","study_design":null,"title":"Prevalence of dementia subtypes in United States Medicare fee-for-service beneficiaries, 2011-2013","title_match":false,"year":2017},{"alzhub_score":68,"alzhub_url":"https://alzhub.org/study/contribution-of-alcohol-use-disorders-to-the-burden-of-dementia-in-29475810","doi":"10.1016/s2468-2667(18)30022-7","journal":"The Lancet. Public health","n_participants":156,"pmid":"29475810","source_url":"https://pubmed.ncbi.nlm.nih.gov/29475810/","study_design":"retrospective cohort","title":"Contribution of alcohol use disorders to the burden of dementia in France 2008-13: a nationwide retrospective cohort study","title_match":true,"year":2018},{"alzhub_score":71,"alzhub_url":"https://alzhub.org/study/prospective-study-of-alcohol-consumption-and-risk-of-dementia-in-12636463","doi":"10.1001/jama.289.11.1405","journal":"JAMA","n_participants":5888,"pmid":"12636463","source_url":"https://pubmed.ncbi.nlm.nih.gov/12636463/","study_design":"cohort study","title":"Prospective study of alcohol consumption and risk of dementia in older adults","title_match":true,"year":2003},{"alzhub_score":46,"alzhub_url":"https://alzhub.org/study/alcohol-intake-in-relation-to-brain-magnetic-resonance-imaging-15447910","doi":"10.1093/ajcn/80.4.992","journal":"The American journal of clinical nutrition","n_participants":509,"pmid":"15447910","source_url":"https://pubmed.ncbi.nlm.nih.gov/15447910/","study_design":null,"title":"Alcohol intake in relation to brain magnetic resonance imaging findings in older persons without dementia","title_match":true,"year":2004},{"alzhub_score":56,"alzhub_url":"https://alzhub.org/study/the-size-and-burden-of-mental-disorders-and-other-disorders-of-the-21896369","doi":"10.1016/j.euroneuro.2011.07.018","journal":"European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology","n_participants":null,"pmid":"21896369","source_url":"https://pubmed.ncbi.nlm.nih.gov/21896369/","study_design":null,"title":"The size and burden of mental disorders and other disorders of the brain in Europe 2010","title_match":false,"year":2011},{"alzhub_score":68,"alzhub_url":"https://alzhub.org/study/non-specialist-health-worker-interventions-for-the-care-of-mental-24249541","doi":"10.1002/14651858.cd009149.pub2","journal":"The Cochrane database of systematic reviews","n_participants":null,"pmid":"24249541","source_url":"https://pubmed.ncbi.nlm.nih.gov/24249541/","study_design":null,"title":"Non-specialist health worker interventions for the care of mental, neurological and substance-abuse disorders in low- and middle-income countries","title_match":false,"year":2013},{"alzhub_score":62,"alzhub_url":"https://alzhub.org/study/metabolic-cardiovascular-syndrome-and-risk-of-dementia-in-japanese-11031212","doi":"10.1161/01.atv.20.10.2255","journal":"Arteriosclerosis, thrombosis, and vascular biology","n_participants":null,"pmid":"11031212","source_url":"https://pubmed.ncbi.nlm.nih.gov/11031212/","study_design":"cohort study","title":"Metabolic cardiovascular syndrome and risk of dementia in Japanese-American elderly men. The Honolulu-Asia aging study","title_match":false,"year":2000},{"alzhub_score":47,"alzhub_url":"https://alzhub.org/study/the-mental-health-workforce-gap-in-low-and-middle-income-countries-a-21379414","doi":"10.2471/blt.10.082784","journal":"Bulletin of the World Health Organization","n_participants":null,"pmid":"21379414","source_url":"https://pubmed.ncbi.nlm.nih.gov/21379414/","study_design":null,"title":"The mental health workforce gap in low- and middle-income countries: a needs-based approach","title_match":false,"year":2011},{"alzhub_score":49,"alzhub_url":"https://alzhub.org/study/psychiatric-illness-in-patients-with-end-stage-renal-disease-9753024","doi":"10.1016/s0002-9343(98)00245-9","journal":"The American journal of medicine","n_participants":null,"pmid":"9753024","source_url":"https://pubmed.ncbi.nlm.nih.gov/9753024/","study_design":"cohort study","title":"Psychiatric illness in patients with end-stage renal disease","title_match":false,"year":1998},{"alzhub_score":47,"alzhub_url":"https://alzhub.org/study/interleukin-6-is-associated-with-cognitive-function-the-northern-16501663","doi":"10.1016/j.jstrokecerebrovasdis.2005.08.009","journal":"Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association","n_participants":null,"pmid":"16501663","source_url":"https://pubmed.ncbi.nlm.nih.gov/16501663/","study_design":"cross-sectional","title":"Interleukin-6 is associated with cognitive function: the Northern Manhattan Study","title_match":false,"year":2006},{"alzhub_score":61,"alzhub_url":"https://alzhub.org/study/risk-factors-for-incident-dementia-in-england-and-wales-the-medical-16414964","doi":"10.1093/ageing/afj030","journal":"Age and ageing","n_participants":4075,"pmid":"16414964","source_url":"https://pubmed.ncbi.nlm.nih.gov/16414964/","study_design":"cohort study","title":"Risk factors for incident dementia in England and Wales: The Medical Research Council Cognitive Function and Ageing Study. A population-based nested case-control study","title_match":false,"year":2006},{"alzhub_score":43,"alzhub_url":"https://alzhub.org/study/understanding-the-broad-spectrum-neuroprotective-action-profile-of-21368374","doi":"10.3233/jad-2011-101803","journal":"Journal of Alzheimer's disease : JAD","n_participants":null,"pmid":"21368374","source_url":"https://pubmed.ncbi.nlm.nih.gov/21368374/","study_design":null,"title":"Understanding the broad-spectrum neuroprotective action profile of green tea polyphenols in aging and neurodegenerative diseases","title_match":false,"year":2011},{"alzhub_score":55,"alzhub_url":"https://alzhub.org/study/the-effect-of-alcohol-and-tobacco-consumption-and-apolipoprotein-e-19750560","doi":"10.1002/gps.2372","journal":"International journal of geriatric psychiatry","n_participants":397,"pmid":"19750560","source_url":"https://pubmed.ncbi.nlm.nih.gov/19750560/","study_design":"cross-sectional","title":"The effect of alcohol and tobacco consumption, and apolipoprotein E genotype, on the age of onset in Alzheimer's disease","title_match":true,"year":2010},{"alzhub_score":43,"alzhub_url":"https://alzhub.org/study/a-descriptive-evaluation-of-eligibility-for-therapy-among-veterans-11873110","doi":"10.1097/00004836-200203000-00015","journal":"Journal of clinical gastroenterology","n_participants":100,"pmid":"11873110","source_url":"https://pubmed.ncbi.nlm.nih.gov/11873110/","study_design":null,"title":"A descriptive evaluation of eligibility for therapy among veterans with chronic hepatitis C virus infection","title_match":false,"year":2002},{"alzhub_score":46,"alzhub_url":"https://alzhub.org/study/characteristics-of-nonresponders-in-a-community-survey-of-the-elderly-7983287","doi":"10.1111/j.1532-5415.1994.tb06506.x","journal":"Journal of the American Geriatrics Society","n_participants":null,"pmid":"7983287","source_url":"https://pubmed.ncbi.nlm.nih.gov/7983287/","study_design":"cross-sectional","title":"Characteristics of nonresponders in a community survey of the elderly","title_match":false,"year":1994},{"alzhub_score":56,"alzhub_url":"https://alzhub.org/study/effect-of-area-level-socioeconomic-deprivation-on-risk-of-cognitive-29430638","doi":"10.1111/jgs.15258","journal":"Journal of the American Geriatrics Society","n_participants":5186,"pmid":"29430638","source_url":"https://pubmed.ncbi.nlm.nih.gov/29430638/","study_design":"cross-sectional","title":"Effect of Area-Level Socioeconomic Deprivation on Risk of Cognitive Dysfunction in Older Adults","title_match":false,"year":2018},{"alzhub_score":50,"alzhub_url":"https://alzhub.org/study/use-of-lipid-lowering-drugs-in-older-adults-with-and-without-dementia-12410906","doi":"10.1046/j.1532-5415.2002.50515.x","journal":"Journal of the American Geriatrics Society","n_participants":null,"pmid":"12410906","source_url":"https://pubmed.ncbi.nlm.nih.gov/12410906/","study_design":"longitudinal study","title":"Use of lipid-lowering drugs in older adults with and without dementia: a community-based epidemiological study","title_match":false,"year":2002},{"alzhub_score":40,"alzhub_url":"https://alzhub.org/study/the-relationship-between-alcohol-consumption-cognitive-performance-8855993","doi":"10.1111/j.1532-5415.1996.tb01364.x","journal":"Journal of the American Geriatrics Society","n_participants":null,"pmid":"8855993","source_url":"https://pubmed.ncbi.nlm.nih.gov/8855993/","study_design":null,"title":"The relationship between alcohol consumption, cognitive performance, and daily functioning in an urban sample of older black Americans","title_match":true,"year":1996},{"alzhub_score":46,"alzhub_url":"https://alzhub.org/study/neutrophil-lymphocyte-ratio-across-psychiatric-diagnoses-a-cross-32690528","doi":"10.1136/bmjopen-2020-036859","journal":"BMJ open","n_participants":null,"pmid":"32690528","source_url":"https://pubmed.ncbi.nlm.nih.gov/32690528/","study_design":"cross-sectional","title":"Neutrophil-lymphocyte ratio across psychiatric diagnoses: a cross-sectional study using electronic health records","title_match":false,"year":2020},{"alzhub_score":55,"alzhub_url":"https://alzhub.org/study/cigarette-smoking-and-gray-matter-brain-volumes-in-middle-age-adults-30741945","doi":"10.1038/s41398-019-0401-1","journal":"Translational psychiatry","n_participants":698,"pmid":"30741945","source_url":"https://pubmed.ncbi.nlm.nih.gov/30741945/","study_design":null,"title":"Cigarette smoking and gray matter brain volumes in middle age adults: the CARDIA Brain MRI sub-study","title_match":false,"year":2019},{"alzhub_score":52,"alzhub_url":"https://alzhub.org/study/health-and-aging-in-elderly-farmers-the-ami-cohort-22839764","doi":"10.1186/1471-2458-12-558","journal":"BMC public health","n_participants":null,"pmid":"22839764","source_url":"https://pubmed.ncbi.nlm.nih.gov/22839764/","study_design":"longitudinal study","title":"Health and aging in elderly farmers: the AMI cohort","title_match":false,"year":2012},{"alzhub_score":77,"alzhub_url":"https://alzhub.org/study/leisure-time-physical-activity-at-midlife-and-the-risk-of-dementia-16239176","doi":"10.1016/s1474-4422(05)70198-8","journal":"The Lancet. Neurology","n_participants":1449,"pmid":"16239176","source_url":"https://pubmed.ncbi.nlm.nih.gov/16239176/","study_design":null,"title":"Leisure-time physical activity at midlife and the risk of dementia and Alzheimer's disease","title_match":false,"year":2005},{"alzhub_score":56,"alzhub_url":"https://alzhub.org/study/midlife-blood-pressure-and-dementia-the-honolulu-asia-aging-study-10794848","doi":"10.1016/s0197-4580(00)00096-8","journal":"Neurobiology of aging","n_participants":null,"pmid":"10794848","source_url":"https://pubmed.ncbi.nlm.nih.gov/10794848/","study_design":null,"title":"Midlife blood pressure and dementia: the Honolulu-Asia aging study","title_match":false,"year":2000},{"alzhub_score":57,"alzhub_url":"https://alzhub.org/study/cardiovascular-death-in-rheumatoid-arthritis-a-population-based-study-15751097","doi":"10.1002/art.20878","journal":"Arthritis and rheumatism","n_participants":354,"pmid":"15751097","source_url":"https://pubmed.ncbi.nlm.nih.gov/15751097/","study_design":null,"title":"Cardiovascular death in rheumatoid arthritis: a population-based study","title_match":false,"year":2005},{"alzhub_score":70,"alzhub_url":"https://alzhub.org/study/dietary-intake-of-antioxidants-and-risk-of-alzheimer-disease-12076218","doi":"10.1001/jama.287.24.3223","journal":"JAMA","n_participants":5395,"pmid":"12076218","source_url":"https://pubmed.ncbi.nlm.nih.gov/12076218/","study_design":"cohort study","title":"Dietary intake of antioxidants and risk of Alzheimer disease","title_match":false,"year":2002},{"alzhub_score":74,"alzhub_url":"https://alzhub.org/study/epidemiologic-studies-of-modifiable-factors-associated-with-cognition-24962204","doi":"10.1186/1471-2458-14-643","journal":"BMC public health","n_participants":null,"pmid":"24962204","source_url":"https://pubmed.ncbi.nlm.nih.gov/24962204/","study_design":"systematic review","title":"Epidemiologic studies of modifiable factors associated with cognition and dementia: systematic review and meta-analysis","title_match":false,"year":2014},{"alzhub_score":65,"alzhub_url":"https://alzhub.org/study/circadian-activity-rhythms-and-risk-of-incident-dementia-and-mild-22162057","doi":"10.1002/ana.22468","journal":"Annals of neurology","n_participants":null,"pmid":"22162057","source_url":"https://pubmed.ncbi.nlm.nih.gov/22162057/","study_design":"cross-sectional","title":"Circadian activity rhythms and risk of incident dementia and mild cognitive impairment in older women","title_match":false,"year":2011},{"alzhub_score":54,"alzhub_url":"https://alzhub.org/study/intake-of-flavonoids-and-risk-of-dementia-10959944","doi":"10.1023/a:1007614613771","journal":"European journal of epidemiology","n_participants":1367,"pmid":"10959944","source_url":"https://pubmed.ncbi.nlm.nih.gov/10959944/","study_design":null,"title":"Intake of flavonoids and risk of dementia","title_match":false,"year":2000},{"alzhub_score":60,"alzhub_url":"https://alzhub.org/study/prevalence-of-psychiatric-disorders-among-older-adults-in-long-term-20522279","doi":"10.1017/s1041610210000608","journal":"International psychogeriatrics","n_participants":74,"pmid":"20522279","source_url":"https://pubmed.ncbi.nlm.nih.gov/20522279/","study_design":null,"title":"Prevalence of psychiatric disorders among older adults in long-term care homes: a systematic review","title_match":false,"year":2010},{"alzhub_score":67,"alzhub_url":"https://alzhub.org/study/smoking-and-risk-of-dementia-and-alzheimer-s-disease-in-a-population-9652667","doi":"10.1016/s0140-6736(97)07541-7","journal":"Lancet (London, England)","n_participants":6870,"pmid":"9652667","source_url":"https://pubmed.ncbi.nlm.nih.gov/9652667/","study_design":"case-control study","title":"Smoking and risk of dementia and Alzheimer's disease in a population-based cohort study: the Rotterdam Study","title_match":false,"year":1998},{"alzhub_score":50,"alzhub_url":"https://alzhub.org/study/prevalence-of-alzheimer-s-disease-and-other-dementias-in-an-elderly-1745343","doi":"10.1212/wnl.41.12.1886","journal":"Neurology","n_participants":null,"pmid":"1745343","source_url":"https://pubmed.ncbi.nlm.nih.gov/1745343/","study_design":null,"title":"Prevalence of Alzheimer's disease and other dementias in an elderly urban population: relationship with age, sex, and education","title_match":false,"year":1991},{"alzhub_score":73,"alzhub_url":"https://alzhub.org/study/alcohol-consumption-as-a-risk-factor-for-dementia-and-cognitive-19546653","doi":"10.1097/jgp.0b013e3181a2fd07","journal":"The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry","n_participants":14646,"pmid":"19546653","source_url":"https://pubmed.ncbi.nlm.nih.gov/19546653/","study_design":"systematic review","title":"Alcohol consumption as a risk factor for dementia and cognitive decline: meta-analysis of prospective studies","title_match":true,"year":2009},{"alzhub_score":49,"alzhub_url":"https://alzhub.org/study/clinical-characteristics-of-a-family-with-chromosome-17-linked-7936241","doi":"10.1212/wnl.44.10.1878","journal":"Neurology","n_participants":null,"pmid":"7936241","source_url":"https://pubmed.ncbi.nlm.nih.gov/7936241/","study_design":null,"title":"Clinical characteristics of a family with chromosome 17-linked disinhibition-dementia-parkinsonism-amyotrophy complex","title_match":false,"year":1994},{"alzhub_score":39,"alzhub_url":"https://alzhub.org/study/nutrition-and-dementia-care-developing-an-evidence-based-model-for-28196475","doi":"10.1186/s12877-017-0443-2","journal":"BMC geriatrics","n_participants":null,"pmid":"28196475","source_url":"https://pubmed.ncbi.nlm.nih.gov/28196475/","study_design":null,"title":"Nutrition and dementia care: developing an evidence-based model for nutritional care in nursing homes","title_match":false,"year":2017},{"alzhub_score":61,"alzhub_url":"https://alzhub.org/study/diabetes-prediabetes-and-brain-aging-the-role-of-healthy-lifestyle-39193914","doi":"10.2337/dc24-0860","journal":"Diabetes care","n_participants":31229,"pmid":"39193914","source_url":"https://pubmed.ncbi.nlm.nih.gov/39193914/","study_design":null,"title":"Diabetes, Prediabetes, and Brain Aging: The Role of Healthy Lifestyle","title_match":false,"year":2024},{"alzhub_score":56,"alzhub_url":"https://alzhub.org/study/risk-factors-for-alzheimer-s-disease-a-prospective-analysis-from-the-12196314","doi":"10.1093/aje/kwf074","journal":"American journal of epidemiology","n_participants":194,"pmid":"12196314","source_url":"https://pubmed.ncbi.nlm.nih.gov/12196314/","study_design":null,"title":"Risk factors for Alzheimer's disease: a prospective analysis from the Canadian Study of Health and Aging","title_match":false,"year":2002},{"alzhub_score":55,"alzhub_url":"https://alzhub.org/study/head-trauma-as-a-risk-factor-for-alzheimer-s-disease-a-collaborative-1833351","doi":"10.1093/ije/20.supplement_2.s28","journal":"International journal of epidemiology","n_participants":null,"pmid":"1833351","source_url":"https://pubmed.ncbi.nlm.nih.gov/1833351/","study_design":"case-control study","title":"Head trauma as a risk factor for Alzheimer's disease: a collaborative re-analysis of case-control studies. EURODEM Risk Factors Research Group","title_match":false,"year":1991},{"alzhub_score":66,"alzhub_url":"https://alzhub.org/study/delirium-risk-factors-in-elderly-hospitalized-patients-9541379","doi":"10.1046/j.1525-1497.1998.00047.x","journal":"Journal of general internal medicine","n_participants":1365,"pmid":"9541379","source_url":"https://pubmed.ncbi.nlm.nih.gov/9541379/","study_design":null,"title":"Delirium risk factors in elderly hospitalized patients","title_match":false,"year":1998},{"alzhub_score":53,"alzhub_url":"https://alzhub.org/study/excessive-daytime-sleepiness-and-subsequent-development-of-parkinson-16275833","doi":"10.1212/01.wnl.0000183056.89590.0d","journal":"Neurology","n_participants":null,"pmid":"16275833","source_url":"https://pubmed.ncbi.nlm.nih.gov/16275833/","study_design":null,"title":"Excessive daytime sleepiness and subsequent development of Parkinson disease","title_match":false,"year":2005},{"alzhub_score":51,"alzhub_url":"https://alzhub.org/study/alcohol-and-cardiovascular-health-the-razor-sharp-double-edged-sword-17825708","doi":"10.1016/j.jacc.2007.04.089","journal":"Journal of the American College of Cardiology","n_participants":null,"pmid":"17825708","source_url":"https://pubmed.ncbi.nlm.nih.gov/17825708/","study_design":null,"title":"Alcohol and cardiovascular health: the razor-sharp double-edged sword","title_match":true,"year":2007},{"alzhub_score":47,"alzhub_url":"https://alzhub.org/study/mediterranean-diet-the-role-of-long-chain-3-fatty-acids-in-fish-31521398","doi":"10.1016/j.neurol.2019.08.005","journal":"Revue neurologique","n_participants":null,"pmid":"31521398","source_url":"https://pubmed.ncbi.nlm.nih.gov/31521398/","study_design":null,"title":"Mediterranean diet: The role of long-chain \u03c9-3 fatty acids in fish; polyphenols in fruits, vegetables, cereals, coffee, tea, cacao and wine; probiotics and vitamins in prevention of stroke, age-related cognitive decline, and Alzheimer disease","title_match":true,"year":2019},{"alzhub_score":62,"alzhub_url":"https://alzhub.org/study/the-2015-dutch-food-based-dietary-guidelines-27049034","doi":"10.1038/ejcn.2016.52","journal":"European journal of clinical nutrition","n_participants":null,"pmid":"27049034","source_url":"https://pubmed.ncbi.nlm.nih.gov/27049034/","study_design":"meta-analysis","title":"The 2015 Dutch food-based dietary guidelines","title_match":false,"year":2016},{"alzhub_score":43,"alzhub_url":"https://alzhub.org/study/inhaled-anesthetic-enhancement-of-amyloid-beta-oligomerization-and-15329595","doi":"10.1097/00000542-200409000-00019","journal":"Anesthesiology","n_participants":null,"pmid":"15329595","source_url":"https://pubmed.ncbi.nlm.nih.gov/15329595/","study_design":null,"title":"Inhaled anesthetic enhancement of amyloid-beta oligomerization and cytotoxicity","title_match":false,"year":2004},{"alzhub_score":59,"alzhub_url":"https://alzhub.org/study/a-case-control-study-of-alzheimer-s-disease-in-australia-2146525","doi":"10.1212/wnl.40.11.1698","journal":"Neurology","n_participants":null,"pmid":"2146525","source_url":"https://pubmed.ncbi.nlm.nih.gov/2146525/","study_design":"case-control study","title":"A case-control study of Alzheimer's disease in Australia","title_match":false,"year":1990},{"alzhub_score":66,"alzhub_url":"https://alzhub.org/study/derivation-and-validation-of-updated-qfracture-algorithm-to-predict-22619194","doi":"10.1136/bmj.e3427","journal":"BMJ (Clinical research ed.)","n_participants":3142673,"pmid":"22619194","source_url":"https://pubmed.ncbi.nlm.nih.gov/22619194/","study_design":"cohort study","title":"Derivation and validation of updated QFracture algorithm to predict risk of osteoporotic fracture in primary care in the United Kingdom: prospective open cohort study","title_match":false,"year":2012},{"alzhub_score":69,"alzhub_url":"https://alzhub.org/study/cognitive-function-trajectories-and-their-determinants-in-older-29691286","doi":"10.1136/jech-2017-210116","journal":"Journal of epidemiology and community health","n_participants":626,"pmid":"29691286","source_url":"https://pubmed.ncbi.nlm.nih.gov/29691286/","study_design":"longitudinal study","title":"Cognitive function trajectories and their determinants in older people: 8 years of follow-up in the English Longitudinal Study of Ageing","title_match":false,"year":2018},{"alzhub_score":51,"alzhub_url":"https://alzhub.org/study/magnesium-in-aging-health-and-diseases-33573164","doi":"10.3390/nu13020463","journal":"Nutrients","n_participants":null,"pmid":"33573164","source_url":"https://pubmed.ncbi.nlm.nih.gov/33573164/","study_design":null,"title":"Magnesium in Aging, Health and Diseases","title_match":false,"year":2021},{"alzhub_score":32,"alzhub_url":"https://alzhub.org/study/nardilysin-in-human-brain-diseases-both-friend-and-foe-23604405","doi":"10.1007/s00726-013-1499-8","journal":"Amino acids","n_participants":null,"pmid":"23604405","source_url":"https://pubmed.ncbi.nlm.nih.gov/23604405/","study_design":null,"title":"Nardilysin in human brain diseases: both friend and foe","title_match":false,"year":2013},{"alzhub_score":34,"alzhub_url":"https://alzhub.org/study/a-pilot-study-of-the-reliability-and-validity-of-the-caregiver-12427167","doi":"10.1046/j.1365-2788.2002.00437.x","journal":"Journal of intellectual disability research : JIDR","n_participants":30,"pmid":"12427167","source_url":"https://pubmed.ncbi.nlm.nih.gov/12427167/","study_design":null,"title":"A pilot study of the reliability and validity of the Caregiver Activity Survey - Intellectual Disability (CAS-ID)","title_match":false,"year":2002},{"alzhub_score":35,"alzhub_url":"https://alzhub.org/study/the-many-neurofaces-of-prohibitins-1-and-2-crucial-for-the-healthy-37524128","doi":"10.1016/j.jchemneu.2023.102321","journal":"Journal of chemical neuroanatomy","n_participants":null,"pmid":"37524128","source_url":"https://pubmed.ncbi.nlm.nih.gov/37524128/","study_design":null,"title":"The many \"Neurofaces\" of Prohibitins 1 and 2: Crucial for the healthy brain, dysregulated in numerous brain disorders","title_match":false,"year":2023},{"alzhub_score":61,"alzhub_url":"https://alzhub.org/study/alcohol-consumption-and-risk-of-dementia-the-rotterdam-study-11830193","doi":"10.1016/s0140-6736(02)07493-7","journal":"Lancet (London, England)","n_participants":5395,"pmid":"11830193","source_url":"https://pubmed.ncbi.nlm.nih.gov/11830193/","study_design":null,"title":"Alcohol consumption and risk of dementia: the Rotterdam Study","title_match":true,"year":2002},{"alzhub_score":39,"alzhub_url":"https://alzhub.org/study/contribution-of-hyperammonemia-and-inflammatory-factors-to-cognitive-22072427","doi":"10.1007/s11011-011-9269-3","journal":"Metabolic brain disease","n_participants":null,"pmid":"22072427","source_url":"https://pubmed.ncbi.nlm.nih.gov/22072427/","study_design":null,"title":"Contribution of hyperammonemia and inflammatory factors to cognitive impairment in minimal hepatic encephalopathy","title_match":false,"year":2012},{"alzhub_score":44,"alzhub_url":"https://alzhub.org/study/nutraceutical-properties-of-mediterranean-diet-and-cognitive-decline-20858954","doi":"10.3233/jad-2010-100942","journal":"Journal of Alzheimer's disease : JAD","n_participants":null,"pmid":"20858954","source_url":"https://pubmed.ncbi.nlm.nih.gov/20858954/","study_design":null,"title":"Nutraceutical properties of Mediterranean diet and cognitive decline: possible underlying mechanisms","title_match":false,"year":2010},{"alzhub_score":49,"alzhub_url":"https://alzhub.org/study/green-tea-epigallocatechin-3-gallate-egcg-reduces-beta-amyloid-18457818","doi":"10.1016/j.brainres.2008.02.107","journal":"Brain research","n_participants":null,"pmid":"18457818","source_url":"https://pubmed.ncbi.nlm.nih.gov/18457818/","study_design":null,"title":"Green tea epigallocatechin-3-gallate (EGCG) reduces beta-amyloid mediated cognitive impairment and modulates tau pathology in Alzheimer transgenic mice","title_match":false,"year":2008},{"alzhub_score":47,"alzhub_url":"https://alzhub.org/study/the-polyphenol-oleuropein-aglycone-protects-tgcrnd8-mice-against-a-23951225","doi":"10.1371/journal.pone.0071702","journal":"PloS one","n_participants":null,"pmid":"23951225","source_url":"https://pubmed.ncbi.nlm.nih.gov/23951225/","study_design":null,"title":"The polyphenol oleuropein aglycone protects TgCRND8 mice against A\u00df plaque pathology","title_match":false,"year":2013},{"alzhub_score":42,"alzhub_url":"https://alzhub.org/study/simultaneous-manipulation-of-multiple-brain-targets-by-green-tea-19040558","doi":"10.1111/j.1755-5949.2008.00060.x","journal":"CNS neuroscience & therapeutics","n_participants":null,"pmid":"19040558","source_url":"https://pubmed.ncbi.nlm.nih.gov/19040558/","study_design":null,"title":"Simultaneous manipulation of multiple brain targets by green tea catechins: a potential neuroprotective strategy for Alzheimer and Parkinson diseases","title_match":false,"year":2008},{"alzhub_score":43,"alzhub_url":"https://alzhub.org/study/chicoric-acid-supplementation-prevents-systemic-inflammation-induced-28003341","doi":"10.1096/fj.201601071r","journal":"FASEB journal : official publication of the Federation of American Societies for Experimental Biology","n_participants":null,"pmid":"28003341","source_url":"https://pubmed.ncbi.nlm.nih.gov/28003341/","study_design":null,"title":"Chicoric acid supplementation prevents systemic inflammation-induced memory impairment and amyloidogenesis via inhibition of NF-\u03baB","title_match":false,"year":2017},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/pomegranate-polyphenols-and-extract-inhibit-nuclear-factor-of-23468550","doi":"10.3945/jn.112.169516","journal":"The Journal of nutrition","n_participants":null,"pmid":"23468550","source_url":"https://pubmed.ncbi.nlm.nih.gov/23468550/","study_design":null,"title":"Pomegranate polyphenols and extract inhibit nuclear factor of activated T-cell activity and microglial activation in vitro and in a transgenic mouse model of Alzheimer disease","title_match":false,"year":2013},{"alzhub_score":58,"alzhub_url":"https://alzhub.org/study/niche-specific-reprogramming-of-epigenetic-landscapes-drives-myeloid-32362324","doi":"10.1016/j.immuni.2020.04.001","journal":"Immunity","n_participants":null,"pmid":"32362324","source_url":"https://pubmed.ncbi.nlm.nih.gov/32362324/","study_design":null,"title":"Niche-Specific Reprogramming of Epigenetic Landscapes Drives Myeloid Cell Diversity in Nonalcoholic Steatohepatitis","title_match":false,"year":2020},{"alzhub_score":56,"alzhub_url":"https://alzhub.org/study/dynamic-shifts-in-the-composition-of-resident-and-recruited-33440159","doi":"10.1016/j.celrep.2020.108626","journal":"Cell reports","n_participants":null,"pmid":"33440159","source_url":"https://pubmed.ncbi.nlm.nih.gov/33440159/","study_design":null,"title":"Dynamic Shifts in the Composition of Resident and Recruited Macrophages Influence Tissue Remodeling in NASH","title_match":false,"year":2021},{"alzhub_score":51,"alzhub_url":"https://alzhub.org/study/soluble-trem2-levels-reflect-the-recruitment-and-expansion-of-trem2-35750138","doi":"10.1016/j.jhep.2022.06.004","journal":"Journal of hepatology","n_participants":null,"pmid":"35750138","source_url":"https://pubmed.ncbi.nlm.nih.gov/35750138/","study_design":null,"title":"Soluble TREM2 levels reflect the recruitment and expansion of TREM2+ macrophages that localize to fibrotic areas and limit NASH","title_match":false,"year":2022},{"alzhub_score":56,"alzhub_url":"https://alzhub.org/study/a-proteo-transcriptomic-map-of-non-alcoholic-fatty-liver-disease-37037945","doi":"10.1038/s42255-023-00775-1","journal":"Nature metabolism","n_participants":306,"pmid":"37037945","source_url":"https://pubmed.ncbi.nlm.nih.gov/37037945/","study_design":null,"title":"A proteo-transcriptomic map of non-alcoholic fatty liver disease signatures","title_match":true,"year":2023},{"alzhub_score":42,"alzhub_url":"https://alzhub.org/study/extracellular-microvesicles-promote-microglia-mediated-pro-33611821","doi":"10.1002/jnr.24813","journal":"Journal of neuroscience research","n_participants":null,"pmid":"33611821","source_url":"https://pubmed.ncbi.nlm.nih.gov/33611821/","study_design":null,"title":"Extracellular microvesicles promote microglia-mediated pro-inflammatory responses to ethanol","title_match":true,"year":2021},{"alzhub_score":35,"alzhub_url":"https://alzhub.org/study/fluoride-activates-microglia-secretes-inflammatory-factors-and-30273629","doi":"10.1016/j.neuro.2018.09.006","journal":"Neurotoxicology","n_participants":null,"pmid":"30273629","source_url":"https://pubmed.ncbi.nlm.nih.gov/30273629/","study_design":null,"title":"Fluoride activates microglia, secretes inflammatory factors and influences synaptic neuron plasticity in the hippocampus of rats","title_match":false,"year":2018},{"alzhub_score":51,"alzhub_url":"https://alzhub.org/study/alcohol-consumption-and-cerebrospinal-fluid-biomarkers-for-40713707","doi":"10.1186/s13195-025-01819-2","journal":"Alzheimer's research & therapy","n_participants":301,"pmid":"40713707","source_url":"https://pubmed.ncbi.nlm.nih.gov/40713707/","study_design":"cohort study","title":"Alcohol consumption and cerebrospinal fluid biomarkers for preclinical alzheimer's disease in a population-based sample of 70-year-olds","title_match":true,"year":2025},{"alzhub_score":57,"alzhub_url":"https://alzhub.org/study/alcohol-consumption-and-cognitive-function-in-late-life-a-16247047","doi":"10.1212/01.wnl.0000180520.35181.24","journal":"Neurology","n_participants":null,"pmid":"16247047","source_url":"https://pubmed.ncbi.nlm.nih.gov/16247047/","study_design":"longitudinal study","title":"Alcohol consumption and cognitive function in late life: a longitudinal community study","title_match":true,"year":2005},{"alzhub_score":43,"alzhub_url":"https://alzhub.org/study/risk-of-dementia-and-alcohol-and-wine-consumption-a-review-of-recent-15455646","doi":"10.4067/s0716-97602004000200003","journal":"Biological research","n_participants":null,"pmid":"15455646","source_url":"https://pubmed.ncbi.nlm.nih.gov/15455646/","study_design":null,"title":"Risk of dementia and alcohol and wine consumption: a review of recent results","title_match":true,"year":2004},{"alzhub_score":55,"alzhub_url":"https://alzhub.org/study/age-and-sex-specific-modifiable-risk-factor-profiles-of-dementia-36593335","doi":"10.1007/s10654-022-00952-8","journal":"European journal of epidemiology","n_participants":497401,"pmid":"36593335","source_url":"https://pubmed.ncbi.nlm.nih.gov/36593335/","study_design":null,"title":"Age- and sex-specific modifiable risk factor profiles of dementia: evidence from the UK Biobank","title_match":false,"year":2023},{"alzhub_score":38,"alzhub_url":"https://alzhub.org/study/suboptimal-hydration-remodels-metabolism-promotes-degenerative-31484829","doi":"10.1172/jci.insight.130949","journal":"JCI insight","n_participants":null,"pmid":"31484829","source_url":"https://pubmed.ncbi.nlm.nih.gov/31484829/","study_design":null,"title":"Suboptimal hydration remodels metabolism, promotes degenerative diseases, and shortens life","title_match":false,"year":2019},{"alzhub_score":49,"alzhub_url":"https://alzhub.org/study/refined-geographic-distribution-of-the-oriental-aldh2-504lys-nee-19456322","doi":"10.1111/j.1469-1809.2009.00517.x","journal":"Annals of human genetics","n_participants":4091,"pmid":"19456322","source_url":"https://pubmed.ncbi.nlm.nih.gov/19456322/","study_design":null,"title":"Refined geographic distribution of the oriental ALDH2*504Lys (nee 487Lys) variant","title_match":false,"year":2009},{"alzhub_score":29,"alzhub_url":"https://alzhub.org/study/depression-dementia-or-pseudodementia-16273012","doi":"10.1017/s1092852900019799","journal":"CNS Spectrums","n_participants":null,"pmid":"16273012","source_url":"https://pubmed.ncbi.nlm.nih.gov/16273012/","study_design":null,"title":"Depression, Dementia, or Pseudodementia?","title_match":false,"year":2005},{"alzhub_score":31,"alzhub_url":"https://alzhub.org/study/performance-on-an-everyday-life-activity-in-persons-diagnosed-with-22355014","doi":"10.1093/alcalc/ags014","journal":"Alcohol and Alcoholism","n_participants":null,"pmid":"22355014","source_url":"https://pubmed.ncbi.nlm.nih.gov/22355014/","study_design":null,"title":"Performance on an Everyday Life Activity in Persons Diagnosed with Alcohol Dependency Compared to Healthy Controls: Relations between a Computerized Shopping Task and Cognitive and Clinical Variables\u2020","title_match":true,"year":2012},{"alzhub_score":54,"alzhub_url":"https://alzhub.org/study/editor-s-view-51de44c0","doi":"10.1093/ageing/afad065","journal":"Age and Ageing","n_participants":240000,"pmid":null,"source_url":"https://doi.org/10.1093/ageing/afad065","study_design":"systematic review","title":"Editor's view","title_match":false,"year":2023},{"alzhub_score":54,"alzhub_url":"https://alzhub.org/study/catastrophic-health-expenditure-among-chinese-adults-living-alone-35922775","doi":"10.1186/s12877-022-03341-8","journal":"BMC Geriatrics","n_participants":null,"pmid":"35922775","source_url":"https://pubmed.ncbi.nlm.nih.gov/35922775/","study_design":"longitudinal study","title":"Catastrophic health expenditure among Chinese adults living alone with cognitive impairment: findings from the CHARLS","title_match":false,"year":2022},{"alzhub_score":28,"alzhub_url":"https://alzhub.org/study/deprescribing-benzodiazepines-30672861","doi":"10.1097/01.npr.0000550253.04526.30","journal":"The Nurse Practitioner","n_participants":null,"pmid":"30672861","source_url":"https://pubmed.ncbi.nlm.nih.gov/30672861/","study_design":null,"title":"Deprescribing benzodiazepines","title_match":false,"year":2019},{"alzhub_score":60,"alzhub_url":"https://alzhub.org/study/geographical-variation-in-dementia-prevalence-across-china-a-38974661","doi":"10.1016/j.lanwpc.2024.101117","journal":"The Lancet Regional Health - Western Pacific","n_participants":17176,"pmid":"38974661","source_url":"https://pubmed.ncbi.nlm.nih.gov/38974661/","study_design":"longitudinal study","title":"Geographical variation in dementia prevalence across China: a geospatial analysis","title_match":false,"year":2024},{"alzhub_score":51,"alzhub_url":"https://alzhub.org/study/the-prevalence-and-risk-factors-study-of-cognitive-impairment-37736696","doi":"10.1111/cns.14478","journal":"CNS Neuroscience & Therapeutics","n_participants":3233,"pmid":"37736696","source_url":"https://pubmed.ncbi.nlm.nih.gov/37736696/","study_design":"cross-sectional","title":"The prevalence and risk factors study of cognitive impairment: Analysis of the elderly population of Han nationality in Hunan province, China","title_match":false,"year":2023},{"alzhub_score":38,"alzhub_url":"https://alzhub.org/study/risk-factors-for-cognitive-impairment-and-dementia-differ-across-41435227","doi":"10.1002/alz70860_106294","journal":"Alzheimer s & Dementia","n_participants":null,"pmid":"41435227","source_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12726156/","study_design":"cross-sectional","title":"Risk Factors for Cognitive Impairment and Dementia Differ Across Classification Codes Evaluating Disadvantaged and Rural Regions in a Kentucky Appalachian Cohort","title_match":false,"year":2025},{"alzhub_score":42,"alzhub_url":"https://alzhub.org/study/a-health-ecological-model-study-of-subjective-cognitive-decline-among-42448799","doi":"10.1038/s41598-026-62335-3","journal":"Scientific Reports","n_participants":null,"pmid":"42448799","source_url":"https://pubmed.ncbi.nlm.nih.gov/42448799/","study_design":"cross-sectional","title":"A health ecological model study of subjective cognitive decline among hypertensive patients in rural Shanxi, China","title_match":false,"year":2026},{"alzhub_score":38,"alzhub_url":"https://alzhub.org/study/trends-in-diagnosis-of-dementia-subtypes-in-nationwide-medicare-500e86e2","doi":"10.1002/alz.093412","journal":"Alzheimer s & Dementia","n_participants":100,"pmid":null,"source_url":"https://doi.org/10.1002/alz.093412","study_design":null,"title":"Trends in Diagnosis of Dementia Subtypes in Nationwide Medicare Claims, 2015\u20102021, by Race/Ethnicity, Sex, and Neighborhood Socioeconomic Status","title_match":false,"year":2024},{"alzhub_score":58,"alzhub_url":"https://alzhub.org/study/research-on-multiple-chronic-conditions-24561755","doi":"10.1097/mlr.0000000000000093","journal":"Medical Care","n_participants":110000,"pmid":"24561755","source_url":"https://pubmed.ncbi.nlm.nih.gov/24561755/","study_design":"longitudinal study","title":"Research on Multiple Chronic Conditions","title_match":false,"year":2014},{"alzhub_score":32,"alzhub_url":"https://alzhub.org/study/partial-mitochondrial-complex-i-inhibitors-as-a-therapy-for-alzheimer-41450141","doi":"10.1002/alz70859_105252","journal":"Alzheimer s & Dementia","n_participants":null,"pmid":"41450141","source_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12741622/","study_design":null,"title":"Partial Mitochondrial Complex I Inhibitors as a Therapy for Alzheimer Disease","title_match":false,"year":2025},{"alzhub_score":49,"alzhub_url":"https://alzhub.org/study/nutrition-and-lifestyle-interventions-in-managing-dyslipidemia-and-40077646","doi":"10.3390/nu17050776","journal":"Nutrients","n_participants":null,"pmid":"40077646","source_url":"https://pubmed.ncbi.nlm.nih.gov/40077646/","study_design":null,"title":"Nutrition and Lifestyle Interventions in Managing Dyslipidemia and Cardiometabolic Risk","title_match":false,"year":2025},{"alzhub_score":51,"alzhub_url":"https://alzhub.org/study/diet-exercise-and-lifestyle-in-glaucoma-current-evidence-and-future-41228444","doi":"10.3390/nu17213369","journal":"Nutrients","n_participants":null,"pmid":"41228444","source_url":"https://pubmed.ncbi.nlm.nih.gov/41228444/","study_design":"cross-sectional","title":"Diet, Exercise, and Lifestyle in Glaucoma: Current Evidence and Future Perspectives","title_match":false,"year":2025},{"alzhub_score":49,"alzhub_url":"https://alzhub.org/study/colorectal-cancer-epidemiology-risk-factors-and-public-health-39938491","doi":"10.1159/000543921","journal":"Digestion","n_participants":null,"pmid":"39938491","source_url":"https://pubmed.ncbi.nlm.nih.gov/39938491/","study_design":null,"title":"Colorectal Cancer: Epidemiology, Risk Factors, and Public Health Strategies","title_match":false,"year":2025},{"alzhub_score":46,"alzhub_url":"https://alzhub.org/study/the-exposome-and-pancreatic-cancer-lifestyle-and-environmental-risk-40368260","doi":"10.1016/j.semcancer.2025.05.004","journal":"Seminars in Cancer Biology","n_participants":null,"pmid":"40368260","source_url":"https://pubmed.ncbi.nlm.nih.gov/40368260/","study_design":null,"title":"The exposome and pancreatic cancer, lifestyle and environmental risk factors for PDAC","title_match":false,"year":2025},{"alzhub_score":58,"alzhub_url":"https://alzhub.org/study/diet-wide-analyses-for-risk-of-colorectal-cancer-prospective-study-of-39779669","doi":"10.1038/s41467-024-55219-5","journal":"Nature Communications","n_participants":null,"pmid":"39779669","source_url":"https://pubmed.ncbi.nlm.nih.gov/39779669/","study_design":null,"title":"Diet-wide analyses for risk of colorectal cancer: prospective study of 12,251 incident cases among 542,778 women in the UK","title_match":false,"year":2025},{"alzhub_score":58,"alzhub_url":"https://alzhub.org/study/health-benefits-of-leisure-time-physical-activity-by-socioeconomic-39909687","doi":"10.1016/s2468-2667(24)00300-1","journal":"The Lancet Public Health","n_participants":909,"pmid":"39909687","source_url":"https://pubmed.ncbi.nlm.nih.gov/39909687/","study_design":null,"title":"Health benefits of leisure-time physical activity by socioeconomic status, lifestyle risk, and mental health: a multicohort study","title_match":false,"year":2025},{"alzhub_score":48,"alzhub_url":"https://alzhub.org/study/mediterranean-diet-why-a-new-pyramid-an-updated-representation-of-the-40087038","doi":"10.1016/j.numecd.2025.103919","journal":"Nutrition Metabolism and Cardiovascular Diseases","n_participants":null,"pmid":"40087038","source_url":"https://pubmed.ncbi.nlm.nih.gov/40087038/","study_design":null,"title":"Mediterranean diet: Why a new pyramid? An updated representation of the traditional Mediterranean diet by the Italian Society of Human Nutrition (SINU)","title_match":false,"year":2025},{"alzhub_score":38,"alzhub_url":"https://alzhub.org/study/lifestyle-and-breast-cancer-prevention-and-treatment-support-40940924","doi":"10.3390/cancers17172830","journal":"Cancers","n_participants":null,"pmid":"40940924","source_url":"https://pubmed.ncbi.nlm.nih.gov/40940924/","study_design":null,"title":"Lifestyle and Breast Cancer: Prevention and Treatment Support","title_match":false,"year":2025},{"alzhub_score":49,"alzhub_url":"https://alzhub.org/study/diet-and-nutrition-in-cardiovascular-disease-prevention-a-scientific-40504596","doi":"10.1093/eurjpc/zwaf310","journal":"European Journal of Preventive Cardiology","n_participants":null,"pmid":"40504596","source_url":"https://pubmed.ncbi.nlm.nih.gov/40504596/","study_design":null,"title":"Diet and nutrition in cardiovascular disease prevention: a scientific statement of the European Association of Preventive Cardiology and the Association of Cardiovascular Nursing & Allied Professions of the European Society of Cardiology","title_match":false,"year":2025},{"alzhub_score":42,"alzhub_url":"https://alzhub.org/study/the-role-of-lifestyle-and-diet-in-the-treatment-of-endometriosis-a-41515258","doi":"10.3390/nu18010142","journal":"Nutrients","n_participants":null,"pmid":"41515258","source_url":"https://pubmed.ncbi.nlm.nih.gov/41515258/","study_design":null,"title":"The Role of Lifestyle and Diet in the Treatment of Endometriosis: A Review","title_match":false,"year":2026},{"alzhub_score":44,"alzhub_url":"https://alzhub.org/study/cancer-statistics-in-china-epidemiology-risk-factors-and-prevention-41523837","doi":"10.21147/j.issn.1000-9604.2025.06.04","journal":"Chinese Journal of Cancer Research","n_participants":null,"pmid":"41523837","source_url":"https://pubmed.ncbi.nlm.nih.gov/41523837/","study_design":null,"title":"Cancer statistics in China: Epidemiology, risk factors, and prevention","title_match":false,"year":2025},{"alzhub_score":40,"alzhub_url":"https://alzhub.org/study/environmental-factors-inducing-gastric-cancer-insights-into-risk-and-39786603","doi":"10.1007/s12672-025-01771-5","journal":"Discover Oncology","n_participants":null,"pmid":"39786603","source_url":"https://pubmed.ncbi.nlm.nih.gov/39786603/","study_design":null,"title":"Environmental factors inducing gastric cancer: insights into risk and prevention strategies","title_match":false,"year":2025},{"alzhub_score":48,"alzhub_url":"https://alzhub.org/study/air-pollution-lifestyle-and-cardiovascular-disease-risk-in-40253932","doi":"10.1016/j.envint.2025.109459","journal":"Environment International","n_participants":null,"pmid":"40253932","source_url":"https://pubmed.ncbi.nlm.nih.gov/40253932/","study_design":null,"title":"Air pollution, lifestyle, and cardiovascular disease risk in northwestern China: A cohort study of over 5.8 million participants","title_match":false,"year":2025},{"alzhub_score":48,"alzhub_url":"https://alzhub.org/study/dementia-risk-reduction-in-china-countryspecific-estimates-of-40879658","doi":"10.1002/alz.70542","journal":"Alzheimer s & Dementia","n_participants":null,"pmid":"40879658","source_url":"https://pubmed.ncbi.nlm.nih.gov/40879658/","study_design":"longitudinal study","title":"Dementia risk reduction in China: Country\u2010specific estimates of modifiable risk factors and population attributable fractions (PAFs)","title_match":false,"year":2025},{"alzhub_score":59,"alzhub_url":"https://alzhub.org/study/associations-of-modifiable-dementia-risk-factors-with-dementia-and-39882349","doi":"10.3389/fpubh.2025.1529969","journal":"Frontiers in Public Health","n_participants":30113,"pmid":"39882349","source_url":"https://pubmed.ncbi.nlm.nih.gov/39882349/","study_design":"longitudinal study","title":"Associations of modifiable dementia risk factors with dementia and cognitive decline: evidence from three prospective cohorts","title_match":false,"year":2025},{"alzhub_score":51,"alzhub_url":"https://alzhub.org/study/how-do-lifestyle-and-environmental-factors-influence-the-sperm-39819375","doi":"10.1186/s13148-025-01815-1","journal":"Clinical Epigenetics","n_participants":null,"pmid":"39819375","source_url":"https://pubmed.ncbi.nlm.nih.gov/39819375/","study_design":null,"title":"How do lifestyle and environmental factors influence the sperm epigenome? Effects on sperm fertilising ability, embryo development, and offspring health","title_match":false,"year":2025},{"alzhub_score":42,"alzhub_url":"https://alzhub.org/study/cardiovascular-risk-reduction-in-metabolic-dysfunction-associated-39826021","doi":"10.1007/s11886-024-02185-5","journal":"Current Cardiology Reports","n_participants":null,"pmid":"39826021","source_url":"https://pubmed.ncbi.nlm.nih.gov/39826021/","study_design":null,"title":"Cardiovascular Risk Reduction in Metabolic Dysfunction-Associated Steatotic Liver Disease and Metabolic Dysfunction-Associated Steatohepatitis","title_match":false,"year":2025},{"alzhub_score":58,"alzhub_url":"https://alzhub.org/study/inflammatory-potential-of-the-diet-and-risk-of-crohn-s-disease-and-39817326","doi":"10.1111/apt.18497","journal":"Alimentary Pharmacology & Therapeutics","n_participants":394255,"pmid":"39817326","source_url":"https://pubmed.ncbi.nlm.nih.gov/39817326/","study_design":null,"title":"Inflammatory Potential of the Diet and Risk of Crohn's Disease and Ulcerative Colitis","title_match":false,"year":2025},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/public-health-strategies-for-hepatocellular-carcinoma-from-risk-40721214","doi":"10.17998/jlc.2025.07.25","journal":"Journal of Liver Cancer","n_participants":null,"pmid":"40721214","source_url":"https://pubmed.ncbi.nlm.nih.gov/40721214/","study_design":null,"title":"Public health strategies for hepatocellular carcinoma: from risk factors to prevention and control","title_match":false,"year":2025},{"alzhub_score":44,"alzhub_url":"https://alzhub.org/study/development-and-evaluation-of-a-free-e-learning-program-on-dementia-39791248","doi":"10.1177/13872877241309112","journal":"Journal of Alzheimer s Disease","n_participants":477,"pmid":"39791248","source_url":"https://pubmed.ncbi.nlm.nih.gov/39791248/","study_design":null,"title":"Development and evaluation of a free e-learning program on dementia risk reduction for the general public: A pre-post study","title_match":false,"year":2025},{"alzhub_score":49,"alzhub_url":"https://alzhub.org/study/nutritional-knowledge-sociodemographic-and-lifestyle-factors-as-40917426","doi":"10.3389/fpubh.2025.1613598","journal":"Frontiers in Public Health","n_participants":4000,"pmid":"40917426","source_url":"https://pubmed.ncbi.nlm.nih.gov/40917426/","study_design":"cross-sectional","title":"Nutritional knowledge, sociodemographic, and lifestyle factors as determinants of diet quality \u2013 a Polish population-based study","title_match":false,"year":2025},{"alzhub_score":53,"alzhub_url":"https://alzhub.org/study/interventions-that-support-lifestyle-behavior-change-for-secondary-40294167","doi":"10.1161/strokeaha.124.045888","journal":"Stroke","n_participants":null,"pmid":"40294167","source_url":"https://pubmed.ncbi.nlm.nih.gov/40294167/","study_design":"longitudinal study","title":"Interventions That Support Lifestyle Behavior Change for Secondary Prevention of Stroke: A Scoping Review","title_match":false,"year":2025},{"alzhub_score":58,"alzhub_url":"https://alzhub.org/study/associations-of-family-history-of-hypertension-genetic-and-lifestyle-40804164","doi":"10.1038/s41440-025-02314-9","journal":"Hypertension Research","n_participants":9001,"pmid":"40804164","source_url":"https://pubmed.ncbi.nlm.nih.gov/40804164/","study_design":"cohort study","title":"Associations of family history of hypertension, genetic, and lifestyle risks with incident hypertension","title_match":false,"year":2025},{"alzhub_score":60,"alzhub_url":"https://alzhub.org/study/brain-age-gap-as-a-predictive-biomarker-that-links-aging-lifestyle-41136538","doi":"10.1038/s43856-025-01100-5","journal":"Communications Medicine","n_participants":38967,"pmid":"41136538","source_url":"https://pubmed.ncbi.nlm.nih.gov/41136538/","study_design":"cohort study","title":"Brain age gap as a predictive biomarker that links aging, lifestyle, and neuropsychiatric health","title_match":false,"year":2025},{"alzhub_score":43,"alzhub_url":"https://alzhub.org/study/a-selfpowered-shapeable-and-wearable-sensor-for-effective-hazard-9adbdf4f","doi":"10.1002/sys3.3","journal":"SmartSys","n_participants":null,"pmid":null,"source_url":"https://doi.org/10.1002/sys3.3","study_design":null,"title":"A Self\u2010Powered, Shapeable, and Wearable Sensor for Effective Hazard Prevention and Biomechanical Monitoring","title_match":false,"year":2025},{"alzhub_score":56,"alzhub_url":"https://alzhub.org/study/clinical-practice-guidelines-on-addressing-cognitive-impairment-in-40046486","doi":"10.4103/indianjpsychiatry.indianjpsychiatry_684_24","journal":"Indian Journal of Psychiatry","n_participants":null,"pmid":"40046486","source_url":"https://pubmed.ncbi.nlm.nih.gov/40046486/","study_design":"meta-analysis","title":"Clinical practice guidelines on addressing cognitive impairment in treatable dementias","title_match":false,"year":2025},{"alzhub_score":58,"alzhub_url":"https://alzhub.org/study/metabolic-dysfunction-associated-steatotic-liver-disease-metabolic-40301749","doi":"10.1186/s12876-025-03814-1","journal":"BMC Gastroenterology","n_participants":296001,"pmid":"40301749","source_url":"https://pubmed.ncbi.nlm.nih.gov/40301749/","study_design":"cohort study","title":"Metabolic dysfunction-associated steatotic liver disease, metabolic alcohol-related liver disease, and incident dementia: a nationwide cohort study","title_match":true,"year":2025},{"alzhub_score":44,"alzhub_url":"https://alzhub.org/study/development-and-validation-of-the-latedem-risk-score-to-predict-41691016","doi":"10.1038/s41598-026-39205-z","journal":"Scientific Reports","n_participants":null,"pmid":"41691016","source_url":"https://pubmed.ncbi.nlm.nih.gov/41691016/","study_design":null,"title":"Development and validation of the LateDem-Risk score to predict dementia incidence in the InveCe.Ab and Trelong Italian cohorts","title_match":false,"year":2026},{"alzhub_score":62,"alzhub_url":"https://alzhub.org/study/association-between-metabolic-syndrome-and-young-onset-dementia-40267374","doi":"10.1212/wnl.0000000000213599","journal":"Neurology","n_participants":1979509,"pmid":"40267374","source_url":"https://pubmed.ncbi.nlm.nih.gov/40267374/","study_design":"cohort study","title":"Association Between Metabolic Syndrome and Young-Onset Dementia","title_match":false,"year":2025},{"alzhub_score":55,"alzhub_url":"https://alzhub.org/study/knowledge-and-practice-of-healthy-behaviors-for-dementia-and-stroke-40307407","doi":"10.1038/s41598-025-99246-8","journal":"Scientific Reports","n_participants":1478,"pmid":"40307407","source_url":"https://pubmed.ncbi.nlm.nih.gov/40307407/","study_design":"cross-sectional","title":"Knowledge and practice of healthy behaviors for dementia and stroke prevention in a United States cohort","title_match":false,"year":2025},{"alzhub_score":48,"alzhub_url":"https://alzhub.org/study/loneliness-and-social-isolation-correlate-with-multiple-modifiable-6ed56966","doi":"10.1007/s10389-025-02412-5","journal":"Journal of Public Health","n_participants":6670,"pmid":null,"source_url":"https://doi.org/10.1007/s10389-025-02412-5","study_design":"cohort study","title":"Loneliness and social isolation correlate with multiple modifiable risk factors for chronic diseases including dementia","title_match":false,"year":2025},{"alzhub_score":59,"alzhub_url":"https://alzhub.org/study/timing-of-risk-factors-prodromal-features-and-comorbidities-of-39819557","doi":"10.1186/s13195-024-01662-x","journal":"Alzheimer s Research & Therapy","n_participants":1686759,"pmid":"39819557","source_url":"https://pubmed.ncbi.nlm.nih.gov/39819557/","study_design":"cohort study","title":"Timing of risk factors, prodromal features, and comorbidities of dementia from a large health claims case\u2013control study","title_match":false,"year":2025},{"alzhub_score":47,"alzhub_url":"https://alzhub.org/study/sex-and-socioeconomic-differences-in-15-year-prevalence-trends-for-40425022","doi":"10.1016/j.lanhl.2025.100711","journal":"The Lancet Healthy Longevity","n_participants":null,"pmid":"40425022","source_url":"https://pubmed.ncbi.nlm.nih.gov/40425022/","study_design":"cross-sectional","title":"Sex and socioeconomic differences in 15-year prevalence trends for modifiable dementia risk factors in Australia: a cross-sectional, time series analysis","title_match":false,"year":2025},{"alzhub_score":42,"alzhub_url":"https://alzhub.org/study/modifiable-risk-factors-for-early-and-late-onset-dementia-using-the-39814657","doi":"10.1016/j.tjpad.2024.100032","journal":"The Journal of Prevention of Alzheimer s Disease","n_participants":null,"pmid":"39814657","source_url":"https://pubmed.ncbi.nlm.nih.gov/39814657/","study_design":"case-control study","title":"Modifiable risk factors for early- and late-onset dementia using the Korean national health insurance service database","title_match":false,"year":2025},{"alzhub_score":54,"alzhub_url":"https://alzhub.org/study/sex-differences-in-modifiable-risk-factors-of-dementia-and-their-42157293","doi":"10.1186/s13293-026-00908-7","journal":"Biology of Sex Differences","n_participants":17182,"pmid":"42157293","source_url":"https://pubmed.ncbi.nlm.nih.gov/42157293/","study_design":"cohort study","title":"Sex differences in modifiable risk factors of dementia and their associations with cognition","title_match":false,"year":2026},{"alzhub_score":42,"alzhub_url":"https://alzhub.org/study/insights-for-dementia-risk-reduction-among-lower-ses-adults-in-oecd-39994664","doi":"10.1186/s12939-025-02386-6","journal":"International Journal for Equity in Health","n_participants":17500,"pmid":"39994664","source_url":"https://pubmed.ncbi.nlm.nih.gov/39994664/","study_design":null,"title":"Insights for dementia risk reduction among lower SES adults in OECD countries: scoping review of interventions targeting multiple common health risk factors","title_match":false,"year":2025},{"alzhub_score":50,"alzhub_url":"https://alzhub.org/study/life-course-modifiable-risk-factors-of-dementia-replicating-the-2024-41434761","doi":"10.1002/alz70860_107692","journal":"Alzheimer s & Dementia","n_participants":5526,"pmid":"41434761","source_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12726475/","study_design":"cross-sectional","title":"Life Course Modifiable Risk Factors of Dementia: Replicating the 2024 Lancet Commission Model in a Single Longitudinal Cohort","title_match":false,"year":2025},{"alzhub_score":40,"alzhub_url":"https://alzhub.org/study/preserved-cognitivefunctional-phenotype-in-centenarians-and-its-41400045","doi":"10.1002/alz.71034","journal":"Alzheimer s & Dementia","n_participants":null,"pmid":"41400045","source_url":"https://pubmed.ncbi.nlm.nih.gov/41400045/","study_design":null,"title":"Preserved cognitive\u2013functional phenotype in centenarians and its association with modifiable risk factors for dementia: Results from the Colombian centenarians project","title_match":false,"year":2025},{"alzhub_score":50,"alzhub_url":"https://alzhub.org/study/variation-of-the-risk-associated-with-potentially-modifiable-risk-39780033","doi":"10.1002/gps.70042","journal":"International Journal of Geriatric Psychiatry","n_participants":null,"pmid":"39780033","source_url":"https://pubmed.ncbi.nlm.nih.gov/39780033/","study_design":"cohort study","title":"Variation of the Risk Associated With Potentially Modifiable Risk Factors for Dementia Between Ethnic Groups Within One Country. A Retrospective Cohort Study Using Routinely Collected Health Data in Aotearoa New Zealand","title_match":false,"year":2025},{"alzhub_score":46,"alzhub_url":"https://alzhub.org/study/development-of-a-neural-network-based-risk-prediction-model-for-mild-40457220","doi":"10.1186/s12889-025-23310-1","journal":"BMC Public Health","n_participants":null,"pmid":"40457220","source_url":"https://pubmed.ncbi.nlm.nih.gov/40457220/","study_design":"longitudinal study","title":"Development of a neural network-based risk prediction model for mild cognitive impairment in older adults with functional disability","title_match":false,"year":2025},{"alzhub_score":34,"alzhub_url":"https://alzhub.org/study/glp-1-receptor-agonists-beyond-glycemic-control-clinical-implications-d1c44bbc","doi":"10.55729/2000-9666.1651","journal":"Journal of Community Hospital Internal Medicine Perspectives","n_participants":null,"pmid":null,"source_url":"https://doi.org/10.55729/2000-9666.1651","study_design":"clinical trial","title":"GLP-1 Receptor Agonists Beyond Glycemic Control: Clinical Implications in Neurodegenerative Disease and Substance Use Disorders","title_match":false,"year":2026},{"alzhub_score":34,"alzhub_url":"https://alzhub.org/study/the-influence-of-lifestyle-on-cognitive-function-and-quality-of-life-41952972","doi":"10.2147/ndt.s565372","journal":"Neuropsychiatric Disease and Treatment","n_participants":null,"pmid":"41952972","source_url":"https://pubmed.ncbi.nlm.nih.gov/41952972/","study_design":null,"title":"The Influence of Lifestyle on Cognitive Function and Quality of Life in People with Dementia","title_match":false,"year":2026},{"alzhub_score":55,"alzhub_url":"https://alzhub.org/study/challenging-the-wine-component-in-mediterranean-diet-scores-cognitive-41305626","doi":"10.3390/nu17223576","journal":"Nutrients","n_participants":75,"pmid":"41305626","source_url":"https://pubmed.ncbi.nlm.nih.gov/41305626/","study_design":"randomized controlled trial","title":"Challenging the Wine Component in Mediterranean Diet Scores: Cognitive Outcomes in Portuguese Adults at High Risk of Dementia","title_match":true,"year":2025},{"alzhub_score":54,"alzhub_url":"https://alzhub.org/study/liver-diseases-and-brain-disorders-genetic-mechanisms-and-biomarker-40230026","doi":"10.1111/jnc.70066","journal":"Journal of Neurochemistry","n_participants":59,"pmid":"40230026","source_url":"https://pubmed.ncbi.nlm.nih.gov/40230026/","study_design":"cohort study","title":"Liver Diseases and Brain Disorders: Genetic Mechanisms and Biomarker Pathways in a Prospective Cohort Study From the UK Biobank","title_match":false,"year":2025},{"alzhub_score":51,"alzhub_url":"https://alzhub.org/study/association-between-leukocyte-telomere-length-and-neurodegenerative-41670794","doi":"10.1007/s00415-025-13479-1","journal":"Journal of Neurology","n_participants":459902,"pmid":"41670794","source_url":"https://pubmed.ncbi.nlm.nih.gov/41670794/","study_design":null,"title":"Association between leukocyte telomere length and neurodegenerative diseases: a prospective cohort in the UK Biobank","title_match":false,"year":2026},{"alzhub_score":32,"alzhub_url":"https://alzhub.org/study/new-vsed-advance-directive-improved-documentation-to-avoid-late-stage-40994267","doi":"10.1017/jme.2025.10176","journal":"The Journal of Law Medicine & Ethics","n_participants":null,"pmid":"40994267","source_url":"https://pubmed.ncbi.nlm.nih.gov/40994267/","study_design":null,"title":"New VSED Advance Directive: Improved Documentation to Avoid Late-Stage Dementia","title_match":false,"year":2025},{"alzhub_score":42,"alzhub_url":"https://alzhub.org/study/propyl-gallate-attenuates-methylglyoxal-induced-alzheimer-like-41516384","doi":"10.3390/ijms27010511","journal":"International Journal of Molecular Sciences","n_participants":null,"pmid":"41516384","source_url":"https://pubmed.ncbi.nlm.nih.gov/41516384/","study_design":null,"title":"Propyl Gallate Attenuates Methylglyoxal-Induced Alzheimer-like Cognitive Deficits and Neuroinflammation in Mice","title_match":false,"year":2026},{"alzhub_score":39,"alzhub_url":"https://alzhub.org/study/ethanol-induces-neuroimmune-dysregulation-and-soluble-trem2-41205777","doi":"10.1016/j.alcohol.2025.10.006","journal":"Alcohol","n_participants":null,"pmid":"41205777","source_url":"https://pubmed.ncbi.nlm.nih.gov/41205777/","study_design":null,"title":"Ethanol induces neuroimmune dysregulation and soluble TREM2 generation in a human iPSC neuron, astrocyte, microglia triculture model","title_match":true,"year":2025},{"alzhub_score":45,"alzhub_url":"https://alzhub.org/study/ethanol-consumption-aggravates-amyloid-pathology-and-40665351","doi":"10.1186/s12974-025-03501-8","journal":"Journal of Neuroinflammation","n_participants":null,"pmid":"40665351","source_url":"https://pubmed.ncbi.nlm.nih.gov/40665351/","study_design":null,"title":"Ethanol consumption aggravates amyloid pathology and neuroinflammation in Alzheimer\u2019s disease associated with inflammasome activation and ASC speck propagation","title_match":true,"year":2025},{"alzhub_score":38,"alzhub_url":"https://alzhub.org/study/synaptic-loss-in-alcohol-use-disorder-clinical-and-mechanistic-41919494","doi":"10.1172/jci204460","journal":"Journal of Clinical Investigation","n_participants":null,"pmid":"41919494","source_url":"https://pubmed.ncbi.nlm.nih.gov/41919494/","study_design":null,"title":"Synaptic loss in alcohol use disorder: clinical and mechanistic insights from a PET imaging study","title_match":true,"year":2026},{"alzhub_score":33,"alzhub_url":"https://alzhub.org/study/pde4a-knockdown-rescues-alcohol-induced-cognitive-impairment-and-42434904","doi":"10.1093/ijnp/pyag031","journal":"The International Journal of Neuropsychopharmacology","n_participants":null,"pmid":"42434904","source_url":"https://pubmed.ncbi.nlm.nih.gov/42434904/","study_design":null,"title":"PDE4A knockdown rescues alcohol-induced cognitive impairment and synaptic dysfunction via the cAMP/PKA/CREB pathway","title_match":true,"year":2026},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/oxidative-stress-alzheimers-disease-dna-methylation-the-role-of-40591736","doi":"10.1042/ebc20253019","journal":"Essays in Biochemistry","n_participants":null,"pmid":"40591736","source_url":"https://pubmed.ncbi.nlm.nih.gov/40591736/","study_design":null,"title":"Oxidative stress \u2013 Alzheimer\u2019s disease \u2013 DNA methylation: the role of arsenic","title_match":false,"year":2025},{"alzhub_score":31,"alzhub_url":"https://alzhub.org/study/updates-on-mediterranean-diet-and-health-status-active-ingredients-0254447a","doi":"10.1111/bph.70441","journal":"Chalmers Research (Chalmers University of Technology)","n_participants":null,"pmid":null,"source_url":"https://doi.org/10.1111/bph.70441","study_design":null,"title":"Updates on Mediterranean diet and health status: active ingredients and pharmacological mechanisms","title_match":false,"year":2026},{"alzhub_score":40,"alzhub_url":"https://alzhub.org/study/type-2-diabetes-and-cognitive-decline-a-neurovascular-perspective-b4e51807","doi":"10.4103/cdrp.cdrp_11_24","journal":"Chronicle of Diabetes Research and Practice","n_participants":null,"pmid":null,"source_url":"https://doi.org/10.4103/cdrp.cdrp_11_24","study_design":"longitudinal study","title":"Type 2 Diabetes and Cognitive Decline: A Neurovascular Perspective","title_match":false,"year":2025},{"alzhub_score":47,"alzhub_url":"https://alzhub.org/study/prevention-of-cognitive-decline-and-dementia-current-evidence-on-42376437","doi":"10.17179/excli2026-9298","journal":"EXCLI journal","n_participants":null,"pmid":"42376437","source_url":"https://pubmed.ncbi.nlm.nih.gov/42376437/","study_design":"meta-analysis","title":"Prevention of cognitive decline and dementia: Current evidence on lifestyle factors and dietary patterns","title_match":false,"year":2026},{"alzhub_score":31,"alzhub_url":"https://alzhub.org/study/marchiafava-bignami-or-delirium-ipoactive-a-case-report-presentation-fbae8441","doi":"10.23736/s2724-6612.24.02569-7","journal":"Minerva Psychiatry","n_participants":null,"pmid":null,"source_url":"https://doi.org/10.23736/s2724-6612.24.02569-7","study_design":null,"title":"Marchiafava-Bignami or delirium ipoactive: a case report presentation","title_match":false,"year":2025},{"alzhub_score":35,"alzhub_url":"https://alzhub.org/study/glp-1-receptor-agonists-in-delirium-and-encephalopathies-a-1839cdb4","doi":"10.1007/s44337-025-00428-0","journal":"Discover Medicine","n_participants":38,"pmid":null,"source_url":"https://doi.org/10.1007/s44337-025-00428-0","study_design":null,"title":"GLP-1 receptor agonists in delirium and encephalopathies: a neuroprotective scoping review","title_match":false,"year":2025},{"alzhub_score":24,"alzhub_url":"https://alzhub.org/study/dependence-dementia-cerebellar-dysfunction-and-myopathy-in-12473964","doi":"10.64719/pb.4213","journal":"Psychopharmacology Bulletin","n_participants":null,"pmid":"12473964","source_url":"https://pubmed.ncbi.nlm.nih.gov/12473964/","study_design":null,"title":"Dependence, Dementia, Cerebellar Dysfunction, and Myopathy in Association With Chronic Isopropanol Ingestion","title_match":false,"year":2002},{"alzhub_score":16,"alzhub_url":"https://alzhub.org/study/alcohol-use-disorder-accelerates-age-related-cognitive-decline-e63c43ee","doi":"10.64898/2026.09.22.26363720","journal":"medRxiv (preprint)","n_participants":1421,"pmid":null,"source_url":"https://doi.org/10.64898/2026.09.22.26363720","study_design":"cross-sectional","title":"Alcohol use disorder accelerates age-related cognitive decline","title_match":true,"year":2026},{"alzhub_score":16,"alzhub_url":"https://alzhub.org/study/patterns-of-modifiable-lifestyle-behavioural-and-health-related-risk-bf9e6ff5","doi":"10.64898/2026.09.24.26363838","journal":"medRxiv (preprint)","n_participants":151832,"pmid":null,"source_url":"https://doi.org/10.64898/2026.09.24.26363838","study_design":null,"title":"Patterns of modifiable lifestyle, behavioural and health-related risk factors and their associations with incident dementia in UK Biobank","title_match":false,"year":2026},{"alzhub_score":54,"alzhub_url":"https://alzhub.org/study/neighborhood-environment-associations-with-cognitive-function-and-39800688","doi":"10.1186/s12916-024-03845-7","journal":"BMC medicine","n_participants":542,"pmid":"39800688","source_url":"https://pubmed.ncbi.nlm.nih.gov/39800688/","study_design":null,"title":"Neighborhood environment associations with cognitive function and structural brain measures in older African Americans","title_match":false,"year":2025},{"alzhub_score":30,"alzhub_url":"https://alzhub.org/study/analysis-of-japanese-nationwide-health-datasets-association-between-37439280","doi":"10.1515/sjpain-2023-0010","journal":"Scandinavian journal of pain","n_participants":null,"pmid":"37439280","source_url":"https://pubmed.ncbi.nlm.nih.gov/37439280/","study_design":null,"title":"Analysis of Japanese nationwide health datasets: association between lifestyle habits and prevalence of neuropathic pain and fibromyalgia with reference to dementia-related diseases and Parkinson's disease","title_match":false,"year":2023},{"alzhub_score":47,"alzhub_url":"https://alzhub.org/study/association-between-alcohol-use-disorders-and-dementia-in-262-703-36525370","doi":"10.1093/gerona/glac252","journal":"The journals of gerontology. Series A, Biological sciences and medical sciences","n_participants":null,"pmid":"36525370","source_url":"https://pubmed.ncbi.nlm.nih.gov/36525370/","study_design":"cohort study","title":"Association Between Alcohol Use Disorders and Dementia in 262,703 Dementia-free Finnish Adults: Is Cardiovascular Disease a Mediator?","title_match":true,"year":2023},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/how-to-create-value-with-unobtrusive-monitoring-technology-in-home-36451119","doi":"10.1186/s12877-022-03550-1","journal":"BMC geriatrics","n_participants":25,"pmid":"36451119","source_url":"https://pubmed.ncbi.nlm.nih.gov/36451119/","study_design":null,"title":"How to create value with unobtrusive monitoring technology in home-based dementia care: a multimethod study among key stakeholders","title_match":false,"year":2022},{"alzhub_score":42,"alzhub_url":"https://alzhub.org/study/american-indian-and-alaska-native-veterans-in-the-indian-health-35363822","doi":"10.1371/journal.pone.0266378","journal":"PloS one","n_participants":12242,"pmid":"35363822","source_url":"https://pubmed.ncbi.nlm.nih.gov/35363822/","study_design":null,"title":"American Indian and Alaska Native veterans in the Indian Health Service: Health status, utilization, and cost","title_match":false,"year":2022},{"alzhub_score":37,"alzhub_url":"https://alzhub.org/study/predictors-of-same-admission-cholecystectomy-in-mild-acute-biliary-34099373","doi":"10.1016/j.hpb.2021.04.002","journal":"HPB : the official journal of the International Hepato Pancreato Biliary Association","n_participants":578,"pmid":"34099373","source_url":"https://pubmed.ncbi.nlm.nih.gov/34099373/","study_design":null,"title":"Predictors of same-admission cholecystectomy in mild, acute, biliary pancreatitis","title_match":false,"year":2021},{"alzhub_score":35,"alzhub_url":"https://alzhub.org/study/associations-between-low-dose-drinking-water-lithium-exposure-and-41643982","doi":"10.1016/j.envpol.2026.127766","journal":"Environmental pollution (Barking, Essex : 1987)","n_participants":null,"pmid":"41643982","source_url":"https://pubmed.ncbi.nlm.nih.gov/41643982/","study_design":null,"title":"Associations between low-dose drinking water lithium exposure and Dementia: A nationwide U.S. ecological study","title_match":true,"year":2026},{"alzhub_score":33,"alzhub_url":"https://alzhub.org/study/factors-associated-with-alzheimer-s-disease-dementia-prevalence-in-58e54ddd","doi":"10.1101/2024.07.16.24310529","journal":"Not indexed","n_participants":null,"pmid":null,"source_url":"https://doi.org/10.1101/2024.07.16.24310529","study_design":null,"title":"Factors associated with Alzheimer's Disease Dementia prevalence in the United States: A county-level spatial machine learning analysis","title_match":false,"year":2024},{"alzhub_score":63,"alzhub_url":"https://alzhub.org/study/midlife-vascular-risk-factors-and-alzheimer-s-disease-in-later-life-11408299","doi":"10.1136/bmj.322.7300.1447","journal":"BMJ","n_participants":1449,"pmid":"11408299","source_url":"https://pubmed.ncbi.nlm.nih.gov/11408299/","study_design":null,"title":"Midlife vascular risk factors and Alzheimer's disease in later life: longitudinal, population based study","title_match":false,"year":2001},{"alzhub_score":46,"alzhub_url":"https://alzhub.org/study/identification-of-disulfiram-as-a-secretase-modulating-compound-with-29358714","doi":"10.1038/s41598-018-19577-7","journal":"Scientific reports","n_participants":null,"pmid":"29358714","source_url":"https://pubmed.ncbi.nlm.nih.gov/29358714/","study_design":null,"title":"Identification of disulfiram as a secretase-modulating compound with beneficial effects on Alzheimer's disease hallmarks","title_match":false,"year":2018},{"alzhub_score":44,"alzhub_url":"https://alzhub.org/study/aluminum-and-alzheimer-s-disease-in-the-21st-century-an-umbrella-42497677","doi":"10.1016/j.neuro.2026.103531","journal":"Neurotoxicology","n_participants":null,"pmid":"42497677","source_url":"https://pubmed.ncbi.nlm.nih.gov/42497677/","study_design":"meta-analysis","title":"Aluminum and Alzheimer's disease in the 21st century: An umbrella review of evidence and controversies","title_match":false,"year":2026},{"alzhub_score":56,"alzhub_url":"https://alzhub.org/study/comparison-of-sociodemographic-and-health-related-characteristics-of-28641372","doi":"10.1093/aje/kwx246","journal":"American Journal of Epidemiology","n_participants":null,"pmid":"28641372","source_url":"https://pubmed.ncbi.nlm.nih.gov/28641372/","study_design":null,"title":"Comparison of Sociodemographic and Health-Related Characteristics of UK Biobank Participants With Those of the General Population","title_match":false,"year":2017},{"alzhub_score":40,"alzhub_url":"https://alzhub.org/study/emerging-histomorphologic-phenotypes-of-chronic-traumatic-21358359","doi":"10.1227/neu.0b013e318212bc7b","journal":"Neurosurgery","n_participants":null,"pmid":"21358359","source_url":"https://pubmed.ncbi.nlm.nih.gov/21358359/","study_design":null,"title":"Emerging histomorphologic phenotypes of chronic traumatic encephalopathy in American athletes","title_match":false,"year":2011},{"alzhub_score":40,"alzhub_url":"https://alzhub.org/study/trehalose-ameliorates-dopaminergic-and-tau-pathology-in-parkin-20546895","doi":"10.1016/j.nbd.2010.05.014","journal":"Neurobiology of disease","n_participants":null,"pmid":"20546895","source_url":"https://pubmed.ncbi.nlm.nih.gov/20546895/","study_design":null,"title":"Trehalose ameliorates dopaminergic and tau pathology in parkin deleted/tau overexpressing mice through autophagy activation","title_match":false,"year":2010},{"alzhub_score":40,"alzhub_url":"https://alzhub.org/study/orally-available-compound-prevents-deficits-in-memory-caused-by-the-17192927","doi":"10.1002/ana.21051","journal":"Annals of neurology","n_participants":null,"pmid":"17192927","source_url":"https://pubmed.ncbi.nlm.nih.gov/17192927/","study_design":null,"title":"Orally available compound prevents deficits in memory caused by the Alzheimer amyloid-beta oligomers","title_match":false,"year":2006},{"alzhub_score":38,"alzhub_url":"https://alzhub.org/study/alzheimer-s-disease-including-focal-presentations-30925614","doi":"10.1055/s-0039-1681041","journal":"Seminars in neurology","n_participants":null,"pmid":"30925614","source_url":"https://pubmed.ncbi.nlm.nih.gov/30925614/","study_design":null,"title":"Alzheimer's Disease Including Focal Presentations","title_match":false,"year":2019},{"alzhub_score":64,"alzhub_url":"https://alzhub.org/study/the-mediterranean-diet-its-components-and-cardiovascular-disease-25447615","doi":"10.1016/j.amjmed.2014.10.014","journal":"The American journal of medicine","n_participants":null,"pmid":"25447615","source_url":"https://pubmed.ncbi.nlm.nih.gov/25447615/","study_design":"randomized controlled trial","title":"The Mediterranean diet, its components, and cardiovascular disease","title_match":false,"year":2015},{"alzhub_score":45,"alzhub_url":"https://alzhub.org/study/polyphenol-rich-foods-in-the-mediterranean-diet-are-associated-with-22349682","doi":"10.3233/jad-2012-111799","journal":"Journal of Alzheimer's disease : JAD","n_participants":447,"pmid":"22349682","source_url":"https://pubmed.ncbi.nlm.nih.gov/22349682/","study_design":null,"title":"Polyphenol-rich foods in the Mediterranean diet are associated with better cognitive function in elderly subjects at high cardiovascular risk","title_match":false,"year":2012},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/the-role-of-diet-in-cognitive-decline-12541015","doi":"10.1007/s00702-002-0766-8","journal":"Journal of neural transmission (Vienna, Austria : 1996)","n_participants":null,"pmid":"12541015","source_url":"https://pubmed.ncbi.nlm.nih.gov/12541015/","study_design":null,"title":"The role of diet in cognitive decline","title_match":false,"year":2003},{"alzhub_score":67,"alzhub_url":"https://alzhub.org/study/mediterranean-diet-and-cognitive-function-in-older-age-23676264","doi":"10.1097/ede.0b013e318294a065","journal":"Epidemiology (Cambridge, Mass.)","n_participants":6174,"pmid":"23676264","source_url":"https://pubmed.ncbi.nlm.nih.gov/23676264/","study_design":null,"title":"Mediterranean diet and cognitive function in older age","title_match":false,"year":2013},{"alzhub_score":52,"alzhub_url":"https://alzhub.org/study/long-term-adherence-to-the-mediterranean-diet-is-associated-with-23365105","doi":"10.3945/jn.112.169896","journal":"The Journal of nutrition","n_participants":16058,"pmid":"23365105","source_url":"https://pubmed.ncbi.nlm.nih.gov/23365105/","study_design":null,"title":"Long-term adherence to the Mediterranean diet is associated with overall cognitive status, but not cognitive decline, in women","title_match":false,"year":2013},{"alzhub_score":40,"alzhub_url":"https://alzhub.org/study/mediterranean-diet-and-cognitive-decline-15482625","doi":"10.1079/phn2004561","journal":"Public health nutrition","n_participants":null,"pmid":"15482625","source_url":"https://pubmed.ncbi.nlm.nih.gov/15482625/","study_design":null,"title":"Mediterranean diet and cognitive decline","title_match":false,"year":2004},{"alzhub_score":47,"alzhub_url":"https://alzhub.org/study/nutrition-and-the-risk-of-alzheimer-s-disease-23865055","doi":"10.1155/2013/524820","journal":"BioMed research international","n_participants":null,"pmid":"23865055","source_url":"https://pubmed.ncbi.nlm.nih.gov/23865055/","study_design":null,"title":"Nutrition and the risk of Alzheimer's disease","title_match":false,"year":2013},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/potential-benefits-of-adherence-to-the-mediterranean-diet-on-23228285","doi":"10.1017/s0029665112002959","journal":"The Proceedings of the Nutrition Society","n_participants":null,"pmid":"23228285","source_url":"https://pubmed.ncbi.nlm.nih.gov/23228285/","study_design":null,"title":"Potential benefits of adherence to the Mediterranean diet on cognitive health","title_match":false,"year":2013},{"alzhub_score":55,"alzhub_url":"https://alzhub.org/study/lifestyle-related-factors-in-predementia-and-dementia-syndromes-18088206","doi":"10.1586/14737175.8.1.133","journal":"Expert review of neurotherapeutics","n_participants":null,"pmid":"18088206","source_url":"https://pubmed.ncbi.nlm.nih.gov/18088206/","study_design":"longitudinal study","title":"Lifestyle-related factors in predementia and dementia syndromes","title_match":false,"year":2008},{"alzhub_score":52,"alzhub_url":"https://alzhub.org/study/evaluation-of-a-dietary-screener-the-mediterranean-eating-pattern-for-28168764","doi":"10.1111/jhn.12451","journal":"Journal of human nutrition and dietetics : the official journal of the British Dietetic Association","n_participants":49,"pmid":"28168764","source_url":"https://pubmed.ncbi.nlm.nih.gov/28168764/","study_design":"cross-sectional","title":"Evaluation of a dietary screener: the Mediterranean Eating Pattern for Americans tool","title_match":false,"year":2017},{"alzhub_score":55,"alzhub_url":"https://alzhub.org/study/the-role-of-lifestyle-factors-and-sleep-duration-for-late-onset-30320581","doi":"10.3233/jad-180529","journal":"Journal of Alzheimer's disease : JAD","n_participants":3755,"pmid":"30320581","source_url":"https://pubmed.ncbi.nlm.nih.gov/30320581/","study_design":null,"title":"The Role of Lifestyle Factors and Sleep Duration for Late-Onset Dementia: A Cohort Study","title_match":false,"year":2018},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/olive-oil-phenols-as-promising-multi-targeting-agents-against-26092624","doi":"10.1007/978-3-319-18365-7_1","journal":"Advances in experimental medicine and biology","n_participants":null,"pmid":"26092624","source_url":"https://pubmed.ncbi.nlm.nih.gov/26092624/","study_design":null,"title":"Olive Oil Phenols as Promising Multi-targeting Agents Against Alzheimer's Disease","title_match":false,"year":2015},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/mediterranean-diet-in-predementia-and-dementia-syndromes-21605047","doi":"10.2174/156720511796391809","journal":"Current Alzheimer research","n_participants":null,"pmid":"21605047","source_url":"https://pubmed.ncbi.nlm.nih.gov/21605047/","study_design":null,"title":"Mediterranean diet in predementia and dementia syndromes","title_match":false,"year":2011},{"alzhub_score":55,"alzhub_url":"https://alzhub.org/study/adherence-to-a-mediterranean-diet-protects-from-cognitive-decline-in-30572567","doi":"10.3390/nu10122007","journal":"Nutrients","n_participants":832,"pmid":"30572567","source_url":"https://pubmed.ncbi.nlm.nih.gov/30572567/","study_design":null,"title":"Adherence to a Mediterranean Diet Protects from Cognitive Decline in the Invecchiare in Chianti Study of Aging","title_match":false,"year":2018},{"alzhub_score":40,"alzhub_url":"https://alzhub.org/study/insights-into-the-neuroprotective-effects-of-i-salvia-officinalis-i-l-35137748","doi":"10.1039/d1fo02988f","journal":"Food & function","n_participants":null,"pmid":"35137748","source_url":"https://pubmed.ncbi.nlm.nih.gov/35137748/","study_design":null,"title":"Insights into the neuroprotective effects of Salvia officinalis L. and Salvia microphylla Kunth in the memory impairment rat model","title_match":false,"year":2022},{"alzhub_score":48,"alzhub_url":"https://alzhub.org/study/mediterranean-diet-its-components-and-amyloid-imaging-biomarkers-29889074","doi":"10.3233/jad-171121","journal":"Journal of Alzheimer's disease : JAD","n_participants":null,"pmid":"29889074","source_url":"https://pubmed.ncbi.nlm.nih.gov/29889074/","study_design":"cross-sectional","title":"Mediterranean Diet, Its Components, and Amyloid Imaging Biomarkers","title_match":false,"year":2018},{"alzhub_score":60,"alzhub_url":"https://alzhub.org/study/dietary-patterns-are-related-to-cognitive-functioning-in-elderly-32472387","doi":"10.1007/s00394-020-02257-6","journal":"European journal of nutrition","n_participants":60,"pmid":"32472387","source_url":"https://pubmed.ncbi.nlm.nih.gov/32472387/","study_design":"cross-sectional","title":"Dietary patterns are related to cognitive functioning in elderly enriched with individuals at increased risk for Alzheimer's disease","title_match":false,"year":2021},{"alzhub_score":47,"alzhub_url":"https://alzhub.org/study/active-cognitive-training-and-rates-of-incident-dementia-22400989","doi":"10.1017/s1355617711001470","journal":"Journal of the International Neuropsychological Society : JINS","n_participants":2802,"pmid":"22400989","source_url":"https://pubmed.ncbi.nlm.nih.gov/22400989/","study_design":null,"title":"ACTIVE cognitive training and rates of incident dementia","title_match":false,"year":2012},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/the-nutritional-components-of-beer-and-its-relationship-with-31295866","doi":"10.3390/nu11071558","journal":"Nutrients","n_participants":null,"pmid":"31295866","source_url":"https://pubmed.ncbi.nlm.nih.gov/31295866/","study_design":null,"title":"The Nutritional Components of Beer and Its Relationship with Neurodegeneration and Alzheimer's Disease","title_match":false,"year":2019},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/hydroxytyrosol-decreases-lps-and-synuclein-induced-microglial-31906130","doi":"10.3390/antiox9010036","journal":"Antioxidants (Basel, Switzerland)","n_participants":null,"pmid":"31906130","source_url":"https://pubmed.ncbi.nlm.nih.gov/31906130/","study_design":null,"title":"Hydroxytyrosol Decreases LPS- and \u03b1-Synuclein-Induced Microglial Activation In Vitro","title_match":false,"year":2019},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/wine-an-aspiring-agent-in-promoting-longevity-and-preventing-chronic-30096779","doi":"10.3390/diseases6030073","journal":"Diseases (Basel, Switzerland)","n_participants":null,"pmid":"30096779","source_url":"https://pubmed.ncbi.nlm.nih.gov/30096779/","study_design":null,"title":"Wine: An Aspiring Agent in Promoting Longevity and Preventing Chronic Diseases","title_match":true,"year":2018},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/wine-intake-in-the-framework-of-a-mediterranean-diet-and-chronic-non-33143082","doi":"10.3390/molecules25215045","journal":"Molecules (Basel, Switzerland)","n_participants":null,"pmid":"33143082","source_url":"https://pubmed.ncbi.nlm.nih.gov/33143082/","study_design":null,"title":"Wine Intake in the Framework of a Mediterranean Diet and Chronic Non-Communicable Diseases: A Short Literature Review of the Last 5 Years","title_match":true,"year":2020},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/the-prevention-of-dementia-19031479","doi":"10.1002/gps.2153","journal":"International journal of geriatric psychiatry","n_participants":null,"pmid":"19031479","source_url":"https://pubmed.ncbi.nlm.nih.gov/19031479/","study_design":null,"title":"The prevention of dementia","title_match":false,"year":2009},{"alzhub_score":40,"alzhub_url":"https://alzhub.org/study/microbial-translocation-is-associated-with-increased-monocyte-18575590","doi":"10.1371/journal.pone.0002516","journal":"PloS one","n_participants":null,"pmid":"18575590","source_url":"https://pubmed.ncbi.nlm.nih.gov/18575590/","study_design":null,"title":"Microbial translocation is associated with increased monocyte activation and dementia in AIDS patients","title_match":false,"year":2008},{"alzhub_score":45,"alzhub_url":"https://alzhub.org/study/psychiatric-phenomena-in-alzheimer-s-disease-iv-disorders-of-behaviour-2397368","doi":"10.1192/bjp.157.1.86","journal":"The British journal of psychiatry : the journal of mental science","n_participants":178,"pmid":"2397368","source_url":"https://pubmed.ncbi.nlm.nih.gov/2397368/","study_design":null,"title":"Psychiatric phenomena in Alzheimer's disease. IV: Disorders of behaviour","title_match":false,"year":1990},{"alzhub_score":64,"alzhub_url":"https://alzhub.org/study/evaluation-and-management-of-oropharyngeal-dysphagia-in-different-22608838","doi":"10.1016/j.archger.2012.04.011","journal":"Archives of gerontology and geriatrics","n_participants":null,"pmid":"22608838","source_url":"https://pubmed.ncbi.nlm.nih.gov/22608838/","study_design":"systematic review","title":"Evaluation and management of oropharyngeal dysphagia in different types of dementia: a systematic review","title_match":false,"year":2013},{"alzhub_score":52,"alzhub_url":"https://alzhub.org/study/psychiatric-illness-predicts-poor-outcome-after-surgery-for-hip-11037100","doi":"10.1017/s0033291799002548","journal":"Psychological medicine","n_participants":731,"pmid":"11037100","source_url":"https://pubmed.ncbi.nlm.nih.gov/11037100/","study_design":null,"title":"Psychiatric illness predicts poor outcome after surgery for hip fracture: a prospective cohort study","title_match":false,"year":2000},{"alzhub_score":43,"alzhub_url":"https://alzhub.org/study/obstructive-sleep-apnea-and-incidence-of-postoperative-delirium-after-22337162","doi":"10.1097/aln.0b013e31824b94fc","journal":"Anesthesiology","n_participants":15,"pmid":"22337162","source_url":"https://pubmed.ncbi.nlm.nih.gov/22337162/","study_design":null,"title":"Obstructive sleep apnea and incidence of postoperative delirium after elective knee replacement in the nondemented elderly","title_match":false,"year":2012},{"alzhub_score":71,"alzhub_url":"https://alzhub.org/study/practice-parameter-risk-of-driving-and-alzheimer-s-disease-an-10881240","doi":"10.1212/wnl.54.12.2205","journal":"Neurology","n_participants":null,"pmid":"10881240","source_url":"https://pubmed.ncbi.nlm.nih.gov/10881240/","study_design":"systematic review","title":"Practice parameter: risk of driving and Alzheimer's disease (an evidence-based review) [RETIRED]: report of the quality standards subcommittee of the American Academy of Neurology","title_match":false,"year":2000},{"alzhub_score":43,"alzhub_url":"https://alzhub.org/study/use-of-topiramate-a-new-anti-epileptic-as-a-mood-stabilizer-9858083","doi":"10.1016/s0165-0327(98)00110-4","journal":"Journal of affective disorders","n_participants":58,"pmid":"9858083","source_url":"https://pubmed.ncbi.nlm.nih.gov/9858083/","study_design":null,"title":"Use of topiramate, a new anti-epileptic as a mood stabilizer","title_match":false,"year":1998},{"alzhub_score":67,"alzhub_url":"https://alzhub.org/study/effectiveness-of-interventions-to-directly-support-food-and-drink-26801619","doi":"10.1186/s12877-016-0196-3","journal":"BMC geriatrics","n_participants":null,"pmid":"26801619","source_url":"https://pubmed.ncbi.nlm.nih.gov/26801619/","study_design":"systematic review","title":"Effectiveness of interventions to directly support food and drink intake in people with dementia: systematic review and meta-analysis","title_match":false,"year":2016},{"alzhub_score":40,"alzhub_url":"https://alzhub.org/study/fatty-acids-and-oxidative-stress-in-psychiatric-disorders-18433515","doi":"10.1186/1471-244x-8-s1-s5","journal":"BMC psychiatry","n_participants":null,"pmid":"18433515","source_url":"https://pubmed.ncbi.nlm.nih.gov/18433515/","study_design":null,"title":"Fatty acids and oxidative stress in psychiatric disorders","title_match":false,"year":2008},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/the-role-of-reduced-fitness-to-drive-due-to-medical-impairments-in-18696384","doi":"10.1080/15389580801895244","journal":"Traffic injury prevention","n_participants":null,"pmid":"18696384","source_url":"https://pubmed.ncbi.nlm.nih.gov/18696384/","study_design":null,"title":"The role of reduced fitness to drive due to medical impairments in explaining crashes involving older drivers","title_match":false,"year":2008},{"alzhub_score":40,"alzhub_url":"https://alzhub.org/study/nursing-home-residents-dying-with-dementia-in-flanders-belgium-a-23523319","doi":"10.1016/j.jamda.2013.01.016","journal":"Journal of the American Medical Directors Association","n_participants":null,"pmid":"23523319","source_url":"https://pubmed.ncbi.nlm.nih.gov/23523319/","study_design":null,"title":"Nursing home residents dying with dementia in Flanders, Belgium: a nationwide postmortem study on clinical characteristics and quality of dying","title_match":false,"year":2013},{"alzhub_score":44,"alzhub_url":"https://alzhub.org/study/is-hospice-associated-with-improved-end-of-life-care-in-nursing-homes-16551318","doi":"10.1111/j.1532-5415.2005.00636.x","journal":"Journal of the American Geriatrics Society","n_participants":97,"pmid":"16551318","source_url":"https://pubmed.ncbi.nlm.nih.gov/16551318/","study_design":null,"title":"Is hospice associated with improved end-of-life care in nursing homes and assisted living facilities?","title_match":false,"year":2006},{"alzhub_score":61,"alzhub_url":"https://alzhub.org/study/prospective-associations-between-single-foods-alzheimer-s-dementia-29966314","doi":"10.3390/nu10070852","journal":"Nutrients","n_participants":2622,"pmid":"29966314","source_url":"https://pubmed.ncbi.nlm.nih.gov/29966314/","study_design":null,"title":"Prospective Associations between Single Foods, Alzheimer's Dementia and Memory Decline in the Elderly","title_match":false,"year":2018},{"alzhub_score":43,"alzhub_url":"https://alzhub.org/study/comparison-of-predictive-modeling-approaches-for-30-day-all-cause-non-26920363","doi":"10.1186/s12874-016-0128-0","journal":"BMC medical research methodology","n_participants":null,"pmid":"26920363","source_url":"https://pubmed.ncbi.nlm.nih.gov/26920363/","study_design":null,"title":"Comparison of predictive modeling approaches for 30-day all-cause non-elective readmission risk","title_match":false,"year":2016},{"alzhub_score":64,"alzhub_url":"https://alzhub.org/study/planning-for-an-uncertain-future-in-progressive-neurological-disease-30115018","doi":"10.1186/s12883-018-1112-6","journal":"BMC neurology","n_participants":29,"pmid":"30115018","source_url":"https://pubmed.ncbi.nlm.nih.gov/30115018/","study_design":"longitudinal study","title":"Planning for an uncertain future in progressive neurological disease: a qualitative study of patient and family decision-making with a focus on eating and drinking","title_match":true,"year":2018},{"alzhub_score":43,"alzhub_url":"https://alzhub.org/study/hippocampal-volume-reduction-in-major-depression-10618023","doi":"10.1176/ajp.157.1.115","journal":"The American journal of psychiatry","n_participants":16,"pmid":"10618023","source_url":"https://pubmed.ncbi.nlm.nih.gov/10618023/","study_design":null,"title":"Hippocampal volume reduction in major depression","title_match":false,"year":2000},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/mri-based-measurement-of-hippocampal-volume-in-patients-with-combat-7793467","doi":"10.1176/ajp.152.7.973","journal":"The American journal of psychiatry","n_participants":null,"pmid":"7793467","source_url":"https://pubmed.ncbi.nlm.nih.gov/7793467/","study_design":null,"title":"MRI-based measurement of hippocampal volume in patients with combat-related posttraumatic stress disorder","title_match":false,"year":1995},{"alzhub_score":43,"alzhub_url":"https://alzhub.org/study/magnetic-resonance-imaging-based-measurement-of-hippocampal-volume-in-8988792","doi":"10.1016/s0006-3223(96)00162-x","journal":"Biological psychiatry","n_participants":17,"pmid":"8988792","source_url":"https://pubmed.ncbi.nlm.nih.gov/8988792/","study_design":null,"title":"Magnetic resonance imaging-based measurement of hippocampal volume in posttraumatic stress disorder related to childhood physical and sexual abuse--a preliminary report","title_match":false,"year":1997},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/magnetic-resonance-imaging-study-of-hippocampal-volume-in-chronic-8931911","doi":"10.1016/s0006-3223(96)00229-6","journal":"Biological psychiatry","n_participants":null,"pmid":"8931911","source_url":"https://pubmed.ncbi.nlm.nih.gov/8931911/","study_design":null,"title":"Magnetic resonance imaging study of hippocampal volume in chronic, combat-related posttraumatic stress disorder","title_match":false,"year":1996},{"alzhub_score":43,"alzhub_url":"https://alzhub.org/study/hippocampal-volume-in-adolescent-onset-alcohol-use-disorders-10784466","doi":"10.1176/appi.ajp.157.5.737","journal":"The American journal of psychiatry","n_participants":12,"pmid":"10784466","source_url":"https://pubmed.ncbi.nlm.nih.gov/10784466/","study_design":null,"title":"Hippocampal volume in adolescent-onset alcohol use disorders","title_match":true,"year":2000},{"alzhub_score":43,"alzhub_url":"https://alzhub.org/study/hippocampal-volume-memory-and-cortisol-status-in-major-depressive-15231442","doi":"10.1016/j.biopsych.2004.04.002","journal":"Biological psychiatry","n_participants":22,"pmid":"15231442","source_url":"https://pubmed.ncbi.nlm.nih.gov/15231442/","study_design":null,"title":"Hippocampal volume, memory, and cortisol status in major depressive disorder: effects of treatment","title_match":false,"year":2004},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/neurocognitive-impairment-in-obstructive-sleep-apnea-22670023","doi":"10.1378/chest.11-2214","journal":"Chest","n_participants":null,"pmid":"22670023","source_url":"https://pubmed.ncbi.nlm.nih.gov/22670023/","study_design":null,"title":"Neurocognitive impairment in obstructive sleep apnea","title_match":false,"year":2012},{"alzhub_score":47,"alzhub_url":"https://alzhub.org/study/amygdala-and-hippocampal-volumes-in-adolescents-and-adults-with-14662552","doi":"10.1001/archpsyc.60.12.1201","journal":"Archives of general psychiatry","n_participants":36,"pmid":"14662552","source_url":"https://pubmed.ncbi.nlm.nih.gov/14662552/","study_design":null,"title":"Amygdala and hippocampal volumes in adolescents and adults with bipolar disorder","title_match":false,"year":2003},{"alzhub_score":40,"alzhub_url":"https://alzhub.org/study/mr-based-in-vivo-hippocampal-volumetrics-2-findings-in-15356639","doi":"10.1038/sj.mp.4001579","journal":"Molecular psychiatry","n_participants":null,"pmid":"15356639","source_url":"https://pubmed.ncbi.nlm.nih.gov/15356639/","study_design":null,"title":"MR-based in vivo hippocampal volumetrics: 2. Findings in neuropsychiatric disorders","title_match":false,"year":2005},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/hippocampal-volume-in-patients-with-alcohol-dependence-10197833","doi":"10.1001/archpsyc.56.4.356","journal":"Archives of general psychiatry","n_participants":null,"pmid":"10197833","source_url":"https://pubmed.ncbi.nlm.nih.gov/10197833/","study_design":null,"title":"Hippocampal volume in patients with alcohol dependence","title_match":true,"year":1999},{"alzhub_score":43,"alzhub_url":"https://alzhub.org/study/anterior-hippocampal-volume-deficits-in-nonamnesic-aging-chronic-7771636","doi":"10.1111/j.1530-0277.1995.tb01478.x","journal":"Alcoholism, clinical and experimental research","n_participants":null,"pmid":"7771636","source_url":"https://pubmed.ncbi.nlm.nih.gov/7771636/","study_design":"cross-sectional","title":"Anterior hippocampal volume deficits in nonamnesic, aging chronic alcoholics","title_match":true,"year":1995},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/reduced-hippocampal-volume-and-total-white-matter-volume-in-12114003","doi":"10.1016/s0006-3223(02)01359-8","journal":"Biological psychiatry","n_participants":null,"pmid":"12114003","source_url":"https://pubmed.ncbi.nlm.nih.gov/12114003/","study_design":null,"title":"Reduced hippocampal volume and total white matter volume in posttraumatic stress disorder","title_match":false,"year":2002},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/reduced-hippocampal-volume-among-adolescents-with-alcohol-use-16054344","doi":"10.1016/j.pscychresns.2005.05.008","journal":"Psychiatry research","n_participants":null,"pmid":"16054344","source_url":"https://pubmed.ncbi.nlm.nih.gov/16054344/","study_design":null,"title":"Reduced hippocampal volume among adolescents with alcohol use disorders without psychiatric comorbidity","title_match":true,"year":2005},{"alzhub_score":43,"alzhub_url":"https://alzhub.org/study/effects-of-alcohol-and-combined-marijuana-and-alcohol-use-during-17169528","doi":"10.1016/j.ntt.2006.10.010","journal":"Neurotoxicology and teratology","n_participants":16,"pmid":"17169528","source_url":"https://pubmed.ncbi.nlm.nih.gov/17169528/","study_design":null,"title":"Effects of alcohol and combined marijuana and alcohol use during adolescence on hippocampal volume and asymmetry","title_match":true,"year":2007},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/effects-of-prenatal-alcohol-exposure-on-hippocampal-volume-verbal-18954482","doi":"10.1017/s1355617708081368","journal":"Journal of the International Neuropsychological Society : JINS","n_participants":null,"pmid":"18954482","source_url":"https://pubmed.ncbi.nlm.nih.gov/18954482/","study_design":null,"title":"Effects of prenatal alcohol exposure on hippocampal volume, verbal learning, and verbal and spatial recall in late childhood","title_match":true,"year":2008},{"alzhub_score":40,"alzhub_url":"https://alzhub.org/study/decreased-hippocampal-n-acetylaspartate-in-the-absence-of-atrophy-in-11750891","doi":"10.1016/s0006-3223(01)01245-8","journal":"Biological psychiatry","n_participants":null,"pmid":"11750891","source_url":"https://pubmed.ncbi.nlm.nih.gov/11750891/","study_design":null,"title":"Decreased hippocampal N-acetylaspartate in the absence of atrophy in posttraumatic stress disorder","title_match":false,"year":2001},{"alzhub_score":50,"alzhub_url":"https://alzhub.org/study/baseline-predictors-for-progression-4-years-after-parkinson-s-disease-30468694","doi":"10.1002/mds.27492","journal":"Movement disorders : official journal of the Movement Disorder Society","n_participants":135,"pmid":"30468694","source_url":"https://pubmed.ncbi.nlm.nih.gov/30468694/","study_design":null,"title":"Baseline predictors for progression 4 years after Parkinson's disease diagnosis in the De Novo Parkinson Cohort (DeNoPa)","title_match":false,"year":2019},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/serotonin-transporter-gene-variants-and-behavior-a-comprehensive-17168841","doi":"10.2174/138945006779025419","journal":"Current drug targets","n_participants":null,"pmid":"17168841","source_url":"https://pubmed.ncbi.nlm.nih.gov/17168841/","study_design":null,"title":"Serotonin transporter gene variants and behavior: a comprehensive review","title_match":false,"year":2006},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/hippocampus-volume-loss-due-to-chronic-heavy-drinking-17067350","doi":"10.1111/j.1530-0277.2006.00223.x","journal":"Alcoholism, clinical and experimental research","n_participants":null,"pmid":"17067350","source_url":"https://pubmed.ncbi.nlm.nih.gov/17067350/","study_design":null,"title":"Hippocampus volume loss due to chronic heavy drinking","title_match":true,"year":2006},{"alzhub_score":40,"alzhub_url":"https://alzhub.org/study/smaller-hippocampal-volume-in-dutch-police-officers-with-15336518","doi":"10.1016/j.biopsych.2004.05.021","journal":"Biological psychiatry","n_participants":null,"pmid":"15336518","source_url":"https://pubmed.ncbi.nlm.nih.gov/15336518/","study_design":null,"title":"Smaller hippocampal volume in Dutch police officers with posttraumatic stress disorder","title_match":false,"year":2004},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/chronic-alcohol-consumption-does-not-cause-hippocampal-neuron-loss-in-9138671","doi":"10.1002/(sici)1098-1063(1997)7:1<78::aid-hipo8>3.0.co;2-3","journal":"Hippocampus","n_participants":null,"pmid":"9138671","source_url":"https://pubmed.ncbi.nlm.nih.gov/9138671/","study_design":null,"title":"Chronic alcohol consumption does not cause hippocampal neuron loss in humans","title_match":true,"year":1997},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/the-effects-of-tobacco-smoke-and-nicotine-on-cognition-and-the-brain-17690985","doi":"10.1007/s11065-007-9035-9","journal":"Neuropsychology review","n_participants":null,"pmid":"17690985","source_url":"https://pubmed.ncbi.nlm.nih.gov/17690985/","study_design":null,"title":"The effects of tobacco smoke and nicotine on cognition and the brain","title_match":false,"year":2007},{"alzhub_score":51,"alzhub_url":"https://alzhub.org/study/cognitive-disorders-in-acute-stroke-prevalence-and-clinical-17406110","doi":"10.1159/000101464","journal":"Cerebrovascular diseases (Basel, Switzerland)","n_participants":190,"pmid":"17406110","source_url":"https://pubmed.ncbi.nlm.nih.gov/17406110/","study_design":null,"title":"Cognitive disorders in acute stroke: prevalence and clinical determinants","title_match":false,"year":2007},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/neuroprotective-action-of-resveratrol-25281824","doi":"10.1016/j.bbadis.2014.09.011","journal":"Biochimica et biophysica acta","n_participants":null,"pmid":"25281824","source_url":"https://pubmed.ncbi.nlm.nih.gov/25281824/","study_design":null,"title":"Neuroprotective action of resveratrol","title_match":false,"year":2015},{"alzhub_score":60,"alzhub_url":"https://alzhub.org/study/alcohol-intake-and-risk-of-dementia-15066068","doi":"10.1111/j.1532-5415.2004.52159.x","journal":"Journal of the American Geriatrics Society","n_participants":260,"pmid":"15066068","source_url":"https://pubmed.ncbi.nlm.nih.gov/15066068/","study_design":"cohort study","title":"Alcohol intake and risk of dementia","title_match":true,"year":2004},{"alzhub_score":67,"alzhub_url":"https://alzhub.org/study/prevalence-of-cognitive-impairment-data-from-the-indianapolis-study-11706107","doi":"10.1212/wnl.57.9.1655","journal":"Neurology","n_participants":351,"pmid":"11706107","source_url":"https://pubmed.ncbi.nlm.nih.gov/11706107/","study_design":"longitudinal study","title":"Prevalence of cognitive impairment: data from the Indianapolis Study of Health and Aging","title_match":false,"year":2001},{"alzhub_score":53,"alzhub_url":"https://alzhub.org/study/heavy-smoking-in-midlife-and-long-term-risk-of-alzheimer-disease-and-20975015","doi":"10.1001/archinternmed.2010.393","journal":"Archives of internal medicine","n_participants":5367,"pmid":"20975015","source_url":"https://pubmed.ncbi.nlm.nih.gov/20975015/","study_design":null,"title":"Heavy smoking in midlife and long-term risk of Alzheimer disease and vascular dementia","title_match":false,"year":2011},{"alzhub_score":60,"alzhub_url":"https://alzhub.org/study/cerebrovascular-and-brain-morphologic-correlates-of-mild-cognitive-11295996","doi":"10.1001/archneur.58.4.643","journal":"Archives of neurology","n_participants":null,"pmid":"11295996","source_url":"https://pubmed.ncbi.nlm.nih.gov/11295996/","study_design":"longitudinal study","title":"Cerebrovascular and brain morphologic correlates of mild cognitive impairment in the National Heart, Lung, and Blood Institute Twin Study","title_match":false,"year":2001},{"alzhub_score":67,"alzhub_url":"https://alzhub.org/study/cardiometabolic-multimorbidity-lifestyle-behaviours-and-cognitive-37150183","doi":"10.1016/s2666-7568(23)00054-5","journal":"The lancet. Healthy longevity","n_participants":147,"pmid":"37150183","source_url":"https://pubmed.ncbi.nlm.nih.gov/37150183/","study_design":"cohort study","title":"Cardiometabolic multimorbidity, lifestyle behaviours, and cognitive function: a multicohort study","title_match":false,"year":2023},{"alzhub_score":52,"alzhub_url":"https://alzhub.org/study/patient-characteristics-associated-with-oral-anticoagulation-control-20653840","doi":"10.1111/j.1538-7836.2010.03996.x","journal":"Journal of thrombosis and haemostasis : JTH","n_participants":124619,"pmid":"20653840","source_url":"https://pubmed.ncbi.nlm.nih.gov/20653840/","study_design":null,"title":"Patient characteristics associated with oral anticoagulation control: results of the Veterans AffaiRs Study to Improve Anticoagulation (VARIA)","title_match":false,"year":2010},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/alcohol-in-moderation-cardioprotection-and-neuroprotection-19032583","doi":"10.1111/j.1530-0277.2008.00828.x","journal":"Alcoholism, clinical and experimental research","n_participants":null,"pmid":"19032583","source_url":"https://pubmed.ncbi.nlm.nih.gov/19032583/","study_design":null,"title":"Alcohol in moderation, cardioprotection, and neuroprotection: epidemiological considerations and mechanistic studies","title_match":true,"year":2009},{"alzhub_score":52,"alzhub_url":"https://alzhub.org/study/association-between-dementia-and-midlife-risk-factors-the-radiation-12588587","doi":"10.1046/j.1532-5415.2003.51117.x","journal":"Journal of the American Geriatrics Society","n_participants":null,"pmid":"12588587","source_url":"https://pubmed.ncbi.nlm.nih.gov/12588587/","study_design":"cohort study","title":"Association between dementia and midlife risk factors: the Radiation Effects Research Foundation Adult Health Study","title_match":false,"year":2003},{"alzhub_score":52,"alzhub_url":"https://alzhub.org/study/increased-risk-of-dementia-in-patients-with-mild-traumatic-brain-23658727","doi":"10.1371/journal.pone.0062422","journal":"PloS one","n_participants":28551,"pmid":"23658727","source_url":"https://pubmed.ncbi.nlm.nih.gov/23658727/","study_design":null,"title":"Increased risk of dementia in patients with mild traumatic brain injury: a nationwide cohort study","title_match":false,"year":2013},{"alzhub_score":52,"alzhub_url":"https://alzhub.org/study/late-onset-seizures-as-a-predictor-of-subsequent-stroke-15081649","doi":"10.1016/s0140-6736(04)15946-1","journal":"Lancet (London, England)","n_participants":4709,"pmid":"15081649","source_url":"https://pubmed.ncbi.nlm.nih.gov/15081649/","study_design":null,"title":"Late-onset seizures as a predictor of subsequent stroke","title_match":false,"year":2004},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/measurement-of-thirteen-biological-markers-in-csf-of-patients-with-16244482","doi":"10.1159/000089137","journal":"Dementia and geriatric cognitive disorders","n_participants":null,"pmid":"16244482","source_url":"https://pubmed.ncbi.nlm.nih.gov/16244482/","study_design":null,"title":"Measurement of thirteen biological markers in CSF of patients with Alzheimer's disease and other dementias","title_match":false,"year":2006},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/gfap-mrna-increases-with-age-in-rat-and-human-brain-8247224","doi":"10.1016/0197-4580(93)90100-p","journal":"Neurobiology of aging","n_participants":null,"pmid":"8247224","source_url":"https://pubmed.ncbi.nlm.nih.gov/8247224/","study_design":null,"title":"GFAP mRNA increases with age in rat and human brain","title_match":false,"year":1993},{"alzhub_score":40,"alzhub_url":"https://alzhub.org/study/protection-against-beta-amyloid-peptide-toxicity-in-vivo-with-long-11325798","doi":"10.1038/sj.bjp.0704047","journal":"British journal of pharmacology","n_participants":null,"pmid":"11325798","source_url":"https://pubmed.ncbi.nlm.nih.gov/11325798/","study_design":null,"title":"Protection against beta-amyloid peptide toxicity in vivo with long-term administration of ferulic acid","title_match":false,"year":2001},{"alzhub_score":40,"alzhub_url":"https://alzhub.org/study/prolonged-oral-cannabinoid-administration-prevents-neuroinflammation-22248049","doi":"10.1186/1742-2094-9-8","journal":"Journal of neuroinflammation","n_participants":null,"pmid":"22248049","source_url":"https://pubmed.ncbi.nlm.nih.gov/22248049/","study_design":null,"title":"Prolonged oral cannabinoid administration prevents neuroinflammation, lowers \u03b2-amyloid levels and improves cognitive performance in Tg APP 2576 mice","title_match":false,"year":2012},{"alzhub_score":38,"alzhub_url":"https://alzhub.org/study/alcohol-drinking-exacerbates-neural-and-behavioral-pathology-in-the-31733664","doi":"10.1016/bs.irn.2019.10.017","journal":"International review of neurobiology","n_participants":null,"pmid":"31733664","source_url":"https://pubmed.ncbi.nlm.nih.gov/31733664/","study_design":null,"title":"Alcohol drinking exacerbates neural and behavioral pathology in the 3xTg-AD mouse model of Alzheimer's disease","title_match":true,"year":2019},{"alzhub_score":48,"alzhub_url":"https://alzhub.org/study/cognitive-function-in-low-income-and-low-literacy-settings-validation-27974474","doi":"10.1093/geronb/gbw139","journal":"The journals of gerontology. Series B, Psychological sciences and social sciences","n_participants":null,"pmid":"27974474","source_url":"https://pubmed.ncbi.nlm.nih.gov/27974474/","study_design":"cross-sectional","title":"Cognitive Function in Low-Income and Low-Literacy Settings: Validation of the Tablet-Based Oxford Cognitive Screen in the Health and Aging in Africa: A Longitudinal Study of an INDEPTH Community in South Africa (HAALSI)","title_match":false,"year":2017},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/epidemiology-and-etiology-of-alzheimer-s-disease-from-genetic-to-non-23919770","doi":"10.2174/15672050113109990155","journal":"Current Alzheimer research","n_participants":null,"pmid":"23919770","source_url":"https://pubmed.ncbi.nlm.nih.gov/23919770/","study_design":null,"title":"Epidemiology and etiology of Alzheimer's disease: from genetic to non-genetic factors","title_match":false,"year":2013},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/neuroprotective-actions-of-dietary-choline-28788094","doi":"10.3390/nu9080815","journal":"Nutrients","n_participants":null,"pmid":"28788094","source_url":"https://pubmed.ncbi.nlm.nih.gov/28788094/","study_design":null,"title":"Neuroprotective Actions of Dietary Choline","title_match":false,"year":2017},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/the-pharmacological-activity-biochemical-properties-and-32210182","doi":"10.3390/foods9030374","journal":"Foods (Basel, Switzerland)","n_participants":null,"pmid":"32210182","source_url":"https://pubmed.ncbi.nlm.nih.gov/32210182/","study_design":null,"title":"The Pharmacological Activity, Biochemical Properties, and Pharmacokinetics of the Major Natural Polyphenolic Flavonoid: Quercetin","title_match":false,"year":2020},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/involvement-of-p2-receptors-in-the-growth-and-survival-of-neurons-in-16102837","doi":"10.1016/j.pharmthera.2005.06.002","journal":"Pharmacology & therapeutics","n_participants":null,"pmid":"16102837","source_url":"https://pubmed.ncbi.nlm.nih.gov/16102837/","study_design":null,"title":"Involvement of P2 receptors in the growth and survival of neurons in the CNS","title_match":false,"year":2006},{"alzhub_score":40,"alzhub_url":"https://alzhub.org/study/lipid-peroxidation-products-and-antioxidants-in-human-disease-9788902","doi":"10.1289/ehp.98106s51229","journal":"Environmental health perspectives","n_participants":null,"pmid":"9788902","source_url":"https://pubmed.ncbi.nlm.nih.gov/9788902/","study_design":null,"title":"Lipid peroxidation products and antioxidants in human disease","title_match":false,"year":1998},{"alzhub_score":40,"alzhub_url":"https://alzhub.org/study/aducanumab-making-a-comeback-in-alzheimer-s-disease-an-old-wine-in-a-35231697","doi":"10.1016/j.biopha.2022.112746","journal":"Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie","n_participants":null,"pmid":"35231697","source_url":"https://pubmed.ncbi.nlm.nih.gov/35231697/","study_design":null,"title":"\"Aducanumab\" making a comeback in Alzheimer's disease: An old wine in a new bottle","title_match":true,"year":2022},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/inhibition-of-the-self-assembly-of-a-and-of-tau-by-polyphenols-31234523","doi":"10.3390/molecules24122316","journal":"Molecules (Basel, Switzerland)","n_participants":null,"pmid":"31234523","source_url":"https://pubmed.ncbi.nlm.nih.gov/31234523/","study_design":null,"title":"Inhibition of the Self-Assembly of A\u03b2 and of Tau by Polyphenols: Mechanistic Studies","title_match":false,"year":2019},{"alzhub_score":43,"alzhub_url":"https://alzhub.org/study/therapeutic-potential-of-semaglutide-a-newer-glp-1-receptor-agonist-35650449","doi":"10.1007/s11095-022-03302-1","journal":"Pharmaceutical research","n_participants":null,"pmid":"35650449","source_url":"https://pubmed.ncbi.nlm.nih.gov/35650449/","study_design":null,"title":"Therapeutic Potential of Semaglutide, a Newer GLP-1 Receptor Agonist, in Abating Obesity, Non-Alcoholic Steatohepatitis and Neurodegenerative diseases: A Narrative Review","title_match":true,"year":2022},{"alzhub_score":71,"alzhub_url":"https://alzhub.org/study/glp-1a-going-beyond-traditional-use-35054924","doi":"10.3390/ijms23020739","journal":"International journal of molecular sciences","n_participants":null,"pmid":"35054924","source_url":"https://pubmed.ncbi.nlm.nih.gov/35054924/","study_design":"systematic review","title":"GLP-1a: Going beyond Traditional Use","title_match":false,"year":2022},{"alzhub_score":64,"alzhub_url":"https://alzhub.org/study/meta-analysis-of-modifiable-risk-factors-for-alzheimer-s-disease-26294005","doi":"10.1136/jnnp-2015-310548","journal":"Journal of neurology, neurosurgery, and psychiatry","n_participants":null,"pmid":"26294005","source_url":"https://pubmed.ncbi.nlm.nih.gov/26294005/","study_design":"systematic review","title":"Meta-analysis of modifiable risk factors for Alzheimer's disease","title_match":false,"year":2015},{"alzhub_score":47,"alzhub_url":"https://alzhub.org/study/bdnf-is-a-novel-marker-of-cognitive-function-in-ageing-women-the-dr-s-18707012","doi":"10.1016/j.nlm.2008.07.014","journal":"Neurobiology of learning and memory","n_participants":1389,"pmid":"18707012","source_url":"https://pubmed.ncbi.nlm.nih.gov/18707012/","study_design":null,"title":"BDNF is a novel marker of cognitive function in ageing women: the DR's EXTRA Study","title_match":false,"year":2008},{"alzhub_score":69,"alzhub_url":"https://alzhub.org/study/a-systematic-review-of-meta-analyses-that-evaluate-risk-factors-for-31306123","doi":"10.3233/jad-190181","journal":"Journal of Alzheimer's disease : JAD","n_participants":null,"pmid":"31306123","source_url":"https://pubmed.ncbi.nlm.nih.gov/31306123/","study_design":"meta-analysis","title":"A Systematic Review of Meta-Analyses that Evaluate Risk Factors for Dementia to Evaluate the Quantity, Quality, and Global Representativeness of Evidence","title_match":false,"year":2019},{"alzhub_score":52,"alzhub_url":"https://alzhub.org/study/fish-consumption-and-cognitive-decline-with-age-in-a-large-community-16216930","doi":"10.1001/archneur.62.12.noc50161","journal":"Archives of neurology","n_participants":null,"pmid":"16216930","source_url":"https://pubmed.ncbi.nlm.nih.gov/16216930/","study_design":"cohort study","title":"Fish consumption and cognitive decline with age in a large community study","title_match":false,"year":2005},{"alzhub_score":40,"alzhub_url":"https://alzhub.org/study/high-fat-diet-induces-brain-insulin-resistance-and-cognitive-27771511","doi":"10.1016/j.bbadis.2016.10.006","journal":"Biochimica et biophysica acta. Molecular basis of disease","n_participants":null,"pmid":"27771511","source_url":"https://pubmed.ncbi.nlm.nih.gov/27771511/","study_design":null,"title":"High fat diet induces brain insulin resistance and cognitive impairment in mice","title_match":false,"year":2017},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/the-sleeping-brain-harnessing-the-power-of-the-glymphatic-system-33212927","doi":"10.3390/brainsci10110868","journal":"Brain sciences","n_participants":null,"pmid":"33212927","source_url":"https://pubmed.ncbi.nlm.nih.gov/33212927/","study_design":null,"title":"The Sleeping Brain: Harnessing the Power of the Glymphatic System through Lifestyle Choices","title_match":false,"year":2020},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/age-associated-chronic-diseases-require-age-old-medicine-role-of-22178471","doi":"10.1016/j.ypmed.2011.11.011","journal":"Preventive medicine","n_participants":null,"pmid":"22178471","source_url":"https://pubmed.ncbi.nlm.nih.gov/22178471/","study_design":null,"title":"Age-associated chronic diseases require age-old medicine: role of chronic inflammation","title_match":false,"year":2012},{"alzhub_score":55,"alzhub_url":"https://alzhub.org/study/risk-factors-and-preventive-interventions-for-alzheimer-disease-state-21555601","doi":"10.1001/archneurol.2011.100","journal":"Archives of neurology","n_participants":null,"pmid":"21555601","source_url":"https://pubmed.ncbi.nlm.nih.gov/21555601/","study_design":"cohort study","title":"Risk factors and preventive interventions for Alzheimer disease: state of the science","title_match":false,"year":2011},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/risk-factors-for-dementia-19864195","doi":"10.1016/s0929-6646(09)60402-2","journal":"Journal of the Formosan Medical Association = Taiwan yi zhi","n_participants":null,"pmid":"19864195","source_url":"https://pubmed.ncbi.nlm.nih.gov/19864195/","study_design":null,"title":"Risk factors for dementia","title_match":false,"year":2009},{"alzhub_score":55,"alzhub_url":"https://alzhub.org/study/development-of-a-new-method-for-assessing-global-risk-of-alzheimer-s-23319292","doi":"10.1007/s11121-012-0313-2","journal":"Prevention science : the official journal of the Society for Prevention Research","n_participants":null,"pmid":"23319292","source_url":"https://pubmed.ncbi.nlm.nih.gov/23319292/","study_design":"cohort study","title":"Development of a new method for assessing global risk of Alzheimer's disease for use in population health approaches to prevention","title_match":false,"year":2013},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/relationship-between-loneliness-psychiatric-disorders-and-physical-25386507","doi":"10.7860/jcdr/2014/10077.4828","journal":"Journal of clinical and diagnostic research : JCDR","n_participants":null,"pmid":"25386507","source_url":"https://pubmed.ncbi.nlm.nih.gov/25386507/","study_design":null,"title":"Relationship between loneliness, psychiatric disorders and physical health ? A review on the psychological aspects of loneliness","title_match":false,"year":2014},{"alzhub_score":43,"alzhub_url":"https://alzhub.org/study/indirect-bright-light-improves-circadian-rest-activity-rhythm-9110101","doi":"10.1016/s0006-3223(97)89928-3","journal":"Biological psychiatry","n_participants":22,"pmid":"9110101","source_url":"https://pubmed.ncbi.nlm.nih.gov/9110101/","study_design":null,"title":"Indirect bright light improves circadian rest-activity rhythm disturbances in demented patients","title_match":false,"year":1997},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/excitotoxicity-bridge-to-various-triggers-in-neurodegenerative-23123057","doi":"10.1016/j.ejphar.2012.10.032","journal":"European journal of pharmacology","n_participants":null,"pmid":"23123057","source_url":"https://pubmed.ncbi.nlm.nih.gov/23123057/","study_design":null,"title":"Excitotoxicity: bridge to various triggers in neurodegenerative disorders","title_match":false,"year":2013},{"alzhub_score":74,"alzhub_url":"https://alzhub.org/study/olfactory-identification-deficits-and-increased-mortality-in-the-26031760","doi":"10.1002/ana.24447","journal":"Annals of neurology","n_participants":null,"pmid":"26031760","source_url":"https://pubmed.ncbi.nlm.nih.gov/26031760/","study_design":null,"title":"Olfactory identification deficits and increased mortality in the community","title_match":false,"year":2015},{"alzhub_score":67,"alzhub_url":"https://alzhub.org/study/modifiable-risk-factors-for-incident-dementia-and-cognitive-35863541","doi":"10.1016/j.jad.2022.07.008","journal":"Journal of affective disorders","n_participants":null,"pmid":"35863541","source_url":"https://pubmed.ncbi.nlm.nih.gov/35863541/","study_design":"meta-analysis","title":"Modifiable risk factors for incident dementia and cognitive impairment: An umbrella review of evidence","title_match":false,"year":2022},{"alzhub_score":74,"alzhub_url":"https://alzhub.org/study/widening-the-spectrum-of-risk-factors-comorbidities-and-prodromal-36342675","doi":"10.1001/jamaneurol.2022.3902","journal":"JAMA neurology","n_participants":345,"pmid":"36342675","source_url":"https://pubmed.ncbi.nlm.nih.gov/36342675/","study_design":"cohort study","title":"Widening the Spectrum of Risk Factors, Comorbidities, and Prodromal Features of Parkinson Disease","title_match":false,"year":2023},{"alzhub_score":59,"alzhub_url":"https://alzhub.org/study/hearing-loss-and-risk-of-mild-cognitive-impairment-and-dementia-28420004","doi":"10.1159/000464281","journal":"Dementia and geriatric cognitive disorders","n_participants":1515,"pmid":"28420004","source_url":"https://pubmed.ncbi.nlm.nih.gov/28420004/","study_design":"cross-sectional","title":"Hearing Loss and Risk of Mild Cognitive Impairment and Dementia: Findings from the Singapore Longitudinal Ageing Study","title_match":false,"year":2017},{"alzhub_score":16,"alzhub_url":"https://alzhub.org/study/modifiable-risk-factors-for-alzheimer-disease-and-related-dementias-35587456","doi":"10.15585/mmwr.mm7120a2","journal":"MMWR. Morbidity and mortality weekly report","n_participants":null,"pmid":"35587456","source_url":"https://pubmed.ncbi.nlm.nih.gov/35587456/","study_design":null,"title":"Modifiable Risk Factors for Alzheimer Disease and Related Dementias Among Adults Aged \u226545 Years - United States, 2019","title_match":false,"year":2022},{"alzhub_score":40,"alzhub_url":"https://alzhub.org/study/inflammation-in-obesity-diabetes-and-related-disorders-35021057","doi":"10.1016/j.immuni.2021.12.013","journal":"Immunity","n_participants":null,"pmid":"35021057","source_url":"https://pubmed.ncbi.nlm.nih.gov/35021057/","study_design":null,"title":"Inflammation in obesity, diabetes, and related disorders","title_match":false,"year":2022},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/free-radicals-properties-sources-targets-and-their-implication-in-25646037","doi":"10.1007/s12291-014-0446-0","journal":"Indian journal of clinical biochemistry : IJCB","n_participants":null,"pmid":"25646037","source_url":"https://pubmed.ncbi.nlm.nih.gov/25646037/","study_design":null,"title":"Free radicals: properties, sources, targets, and their implication in various diseases","title_match":false,"year":2015},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/health-benefits-of-docosahexaenoic-acid-dha-10479465","doi":"10.1006/phrs.1999.0495","journal":"Pharmacological research","n_participants":null,"pmid":"10479465","source_url":"https://pubmed.ncbi.nlm.nih.gov/10479465/","study_design":null,"title":"Health benefits of docosahexaenoic acid (DHA)","title_match":false,"year":1999},{"alzhub_score":66,"alzhub_url":"https://alzhub.org/study/environmental-risk-factors-for-rem-sleep-behavior-disorder-a-22744670","doi":"10.1212/wnl.0b013e31825dd383","journal":"Neurology","n_participants":694,"pmid":"22744670","source_url":"https://pubmed.ncbi.nlm.nih.gov/22744670/","study_design":"case-control study","title":"Environmental risk factors for REM sleep behavior disorder: a multicenter case-control study","title_match":false,"year":2012},{"alzhub_score":40,"alzhub_url":"https://alzhub.org/study/apoe-genotype-and-alzheimer-s-disease-the-influence-of-lifestyle-and-34275270","doi":"10.1021/acschemneuro.1c00295","journal":"ACS chemical neuroscience","n_participants":null,"pmid":"34275270","source_url":"https://pubmed.ncbi.nlm.nih.gov/34275270/","study_design":null,"title":"APOE Genotype and Alzheimer's Disease: The Influence of Lifestyle and Environmental Factors","title_match":false,"year":2021},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/can-the-controversy-of-the-role-of-aluminum-in-alzheimer-s-disease-be-8772802","doi":"10.1080/009841096161104","journal":"Journal of toxicology and environmental health","n_participants":null,"pmid":"8772802","source_url":"https://pubmed.ncbi.nlm.nih.gov/8772802/","study_design":null,"title":"Can the controversy of the role of aluminum in Alzheimer's disease be resolved? What are the suggested approaches to this controversy and methodological issues to be considered?","title_match":false,"year":1996},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/abad-directly-links-abeta-to-mitochondrial-toxicity-in-alzheimer-s-15087549","doi":"10.1126/science.1091230","journal":"Science (New York, N.Y.)","n_participants":null,"pmid":"15087549","source_url":"https://pubmed.ncbi.nlm.nih.gov/15087549/","study_design":null,"title":"ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease","title_match":false,"year":2004},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/genetic-architectures-of-psychiatric-disorders-the-emerging-picture-22777127","doi":"10.1038/nrg3240","journal":"Nature reviews. Genetics","n_participants":null,"pmid":"22777127","source_url":"https://pubmed.ncbi.nlm.nih.gov/22777127/","study_design":null,"title":"Genetic architectures of psychiatric disorders: the emerging picture and its implications","title_match":false,"year":2012},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/mitochondrial-bioenergetic-deficit-precedes-alzheimer-s-pathology-in-19667196","doi":"10.1073/pnas.0903563106","journal":"Proceedings of the National Academy of Sciences of the United States of America","n_participants":null,"pmid":"19667196","source_url":"https://pubmed.ncbi.nlm.nih.gov/19667196/","study_design":null,"title":"Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease","title_match":false,"year":2009},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/dendritic-spine-pathology-cause-or-consequence-of-neurological-12086707","doi":"10.1016/s0165-0173(02)00158-3","journal":"Brain research. Brain research reviews","n_participants":null,"pmid":"12086707","source_url":"https://pubmed.ncbi.nlm.nih.gov/12086707/","study_design":null,"title":"Dendritic spine pathology: cause or consequence of neurological disorders?","title_match":false,"year":2002},{"alzhub_score":62,"alzhub_url":"https://alzhub.org/study/olfactory-dysfunction-in-parkinsonism-a-general-deficit-unrelated-to-3399075","doi":"10.1212/wnl.38.8.1237","journal":"Neurology","n_participants":24,"pmid":"3399075","source_url":"https://pubmed.ncbi.nlm.nih.gov/3399075/","study_design":"longitudinal study","title":"Olfactory dysfunction in parkinsonism: a general deficit unrelated to neurologic signs, disease stage, or disease duration","title_match":false,"year":1988},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/puerarin-a-review-of-pharmacological-effects-24339367","doi":"10.1002/ptr.5083","journal":"Phytotherapy research : PTR","n_participants":null,"pmid":"24339367","source_url":"https://pubmed.ncbi.nlm.nih.gov/24339367/","study_design":null,"title":"Puerarin: a review of pharmacological effects","title_match":false,"year":2014},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/the-binding-of-thioflavin-t-to-amyloid-fibrils-localisation-and-15629655","doi":"10.1016/j.jsb.2004.08.002","journal":"Journal of structural biology","n_participants":null,"pmid":"15629655","source_url":"https://pubmed.ncbi.nlm.nih.gov/15629655/","study_design":null,"title":"The binding of thioflavin-T to amyloid fibrils: localisation and implications","title_match":false,"year":2005},{"alzhub_score":40,"alzhub_url":"https://alzhub.org/study/a-genomic-pathway-approach-to-a-complex-disease-axon-guidance-and-17571925","doi":"10.1371/journal.pgen.0030098","journal":"PLoS genetics","n_participants":null,"pmid":"17571925","source_url":"https://pubmed.ncbi.nlm.nih.gov/17571925/","study_design":null,"title":"A genomic pathway approach to a complex disease: axon guidance and Parkinson disease","title_match":false,"year":2007},{"alzhub_score":45,"alzhub_url":"https://alzhub.org/study/modifiable-pathways-in-alzheimer-s-disease-mendelian-randomisation-29212772","doi":"10.1136/bmj.j5375","journal":"BMJ (Clinical research ed.)","n_participants":null,"pmid":"29212772","source_url":"https://pubmed.ncbi.nlm.nih.gov/29212772/","study_design":null,"title":"Modifiable pathways in Alzheimer's disease: Mendelian randomisation analysis","title_match":false,"year":2017},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/trace-amounts-of-copper-in-water-induce-beta-amyloid-plaques-and-12920183","doi":"10.1073/pnas.1832769100","journal":"Proceedings of the National Academy of Sciences of the United States of America","n_participants":null,"pmid":"12920183","source_url":"https://pubmed.ncbi.nlm.nih.gov/12920183/","study_design":null,"title":"Trace amounts of copper in water induce beta-amyloid plaques and learning deficits in a rabbit model of Alzheimer's disease","title_match":false,"year":2003},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/presence-of-both-odor-identification-and-detection-deficits-in-3607528","doi":"10.1016/0361-9230(87)90129-8","journal":"Brain research bulletin","n_participants":null,"pmid":"3607528","source_url":"https://pubmed.ncbi.nlm.nih.gov/3607528/","study_design":null,"title":"Presence of both odor identification and detection deficits in Alzheimer's disease","title_match":false,"year":1987},{"alzhub_score":64,"alzhub_url":"https://alzhub.org/study/alzheimer-s-disease-a-study-of-epidemiological-aspects-6742780","doi":"10.1002/ana.410150406","journal":"Annals of neurology","n_participants":40,"pmid":"6742780","source_url":"https://pubmed.ncbi.nlm.nih.gov/6742780/","study_design":"case-control study","title":"Alzheimer's disease: a study of epidemiological aspects","title_match":false,"year":1984},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/mapping-cortical-change-in-alzheimer-s-disease-brain-development-and-15501091","doi":"10.1016/j.neuroimage.2004.07.071","journal":"NeuroImage","n_participants":null,"pmid":"15501091","source_url":"https://pubmed.ncbi.nlm.nih.gov/15501091/","study_design":null,"title":"Mapping cortical change in Alzheimer's disease, brain development, and schizophrenia","title_match":false,"year":2004},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/regulation-of-gut-microbiota-and-metabolic-endotoxemia-with-dietary-31547555","doi":"10.3390/nu11102277","journal":"Nutrients","n_participants":null,"pmid":"31547555","source_url":"https://pubmed.ncbi.nlm.nih.gov/31547555/","study_design":null,"title":"Regulation of Gut Microbiota and Metabolic Endotoxemia with Dietary Factors","title_match":false,"year":2019},{"alzhub_score":43,"alzhub_url":"https://alzhub.org/study/mannan-oligosaccharide-attenuates-cognitive-and-behavioral-disorders-33839232","doi":"10.1016/j.bbi.2021.04.005","journal":"Brain, behavior, and immunity","n_participants":null,"pmid":"33839232","source_url":"https://pubmed.ncbi.nlm.nih.gov/33839232/","study_design":null,"title":"Mannan oligosaccharide attenuates cognitive and behavioral disorders in the 5xFAD Alzheimer's disease mouse model via regulating the gut microbiota-brain axis","title_match":false,"year":2021},{"alzhub_score":40,"alzhub_url":"https://alzhub.org/study/loss-of-neurons-in-the-nucleus-basalis-of-meynert-in-alzheimer-s-6637393","doi":"10.1007/bf00697388","journal":"Acta neuropathologica","n_participants":null,"pmid":"6637393","source_url":"https://pubmed.ncbi.nlm.nih.gov/6637393/","study_design":null,"title":"Loss of neurons in the nucleus basalis of Meynert in Alzheimer's disease, paralysis agitans and Korsakoff's Disease","title_match":false,"year":1983},{"alzhub_score":60,"alzhub_url":"https://alzhub.org/study/associations-between-cerebrovascular-risk-factors-and-parkinson-31464350","doi":"10.1002/ana.25564","journal":"Annals of neurology","n_participants":null,"pmid":"31464350","source_url":"https://pubmed.ncbi.nlm.nih.gov/31464350/","study_design":"cohort study","title":"Associations between cerebrovascular risk factors and parkinson disease","title_match":false,"year":2019},{"alzhub_score":69,"alzhub_url":"https://alzhub.org/study/comparison-of-dementia-risk-after-age-50-between-individuals-with-and-33394681","doi":"10.1097/qad.0000000000002806","journal":"AIDS (London, England)","n_participants":5381,"pmid":"33394681","source_url":"https://pubmed.ncbi.nlm.nih.gov/33394681/","study_design":"cohort study","title":"Comparison of dementia risk after age 50 between individuals with and without HIV infection","title_match":false,"year":2021},{"alzhub_score":76,"alzhub_url":"https://alzhub.org/study/patients-with-chronic-kidney-disease-are-at-an-elevated-risk-of-23020192","doi":"10.1186/1471-2369-13-129","journal":"BMC nephrology","n_participants":37049,"pmid":"23020192","source_url":"https://pubmed.ncbi.nlm.nih.gov/23020192/","study_design":"cohort study","title":"Patients with chronic kidney disease are at an elevated risk of dementia: a population-based cohort study in Taiwan","title_match":false,"year":2012},{"alzhub_score":43,"alzhub_url":"https://alzhub.org/study/lifestyle-factors-and-plasma-biomarkers-of-alzheimer-s-disease-a-40082178","doi":"10.1016/j.tjpad.2025.100130","journal":"The journal of prevention of Alzheimer's disease","n_participants":null,"pmid":"40082178","source_url":"https://pubmed.ncbi.nlm.nih.gov/40082178/","study_design":null,"title":"Lifestyle factors and plasma biomarkers of Alzheimer's disease: A narrative review","title_match":false,"year":2025},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/molecular-genetics-of-neuropsychiatric-illness-some-musings-38028602","doi":"10.3389/fgene.2023.1203017","journal":"Frontiers in genetics","n_participants":null,"pmid":"38028602","source_url":"https://pubmed.ncbi.nlm.nih.gov/38028602/","study_design":null,"title":"Molecular genetics of neuropsychiatric illness: some musings","title_match":false,"year":2023},{"alzhub_score":46,"alzhub_url":"https://alzhub.org/study/a-polygenic-risk-score-predicts-mosaic-loss-of-chromosome-y-in-34895331","doi":"10.1186/s13578-021-00716-z","journal":"Cell & bioscience","n_participants":null,"pmid":"34895331","source_url":"https://pubmed.ncbi.nlm.nih.gov/34895331/","study_design":null,"title":"A polygenic risk score predicts mosaic loss of chromosome Y in circulating blood cells","title_match":false,"year":2021},{"alzhub_score":43,"alzhub_url":"https://alzhub.org/study/a-decade-in-psychiatric-gwas-research-29942042","doi":"10.1038/s41380-018-0055-z","journal":"Molecular psychiatry","n_participants":null,"pmid":"29942042","source_url":"https://pubmed.ncbi.nlm.nih.gov/29942042/","study_design":null,"title":"A decade in psychiatric GWAS research","title_match":false,"year":2019},{"alzhub_score":38,"alzhub_url":"https://alzhub.org/study/what-is-early-onset-dementia-19604328","doi":"10.1111/j.1479-8301.2009.00274.x","journal":"Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society","n_participants":null,"pmid":"19604328","source_url":"https://pubmed.ncbi.nlm.nih.gov/19604328/","study_design":null,"title":"What is 'early onset dementia'?","title_match":false,"year":2009},{"alzhub_score":43,"alzhub_url":"https://alzhub.org/study/epigenome-wide-analyses-identify-dna-methylation-signatures-of-32789163","doi":"10.1002/dad2.12078","journal":"Alzheimer's & dementia (Amsterdam, Netherlands)","n_participants":null,"pmid":"32789163","source_url":"https://pubmed.ncbi.nlm.nih.gov/32789163/","study_design":null,"title":"Epigenome-wide analyses identify DNA methylation signatures of dementia risk","title_match":false,"year":2020},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/a-history-of-repeated-alcohol-intoxication-promotes-cognitive-37308288","doi":"10.1523/eneuro.0456-22.2023","journal":"eNeuro","n_participants":null,"pmid":"37308288","source_url":"https://pubmed.ncbi.nlm.nih.gov/37308288/","study_design":null,"title":"A History of Repeated Alcohol Intoxication Promotes Cognitive Impairment and Gene Expression Signatures of Disease Progression in the 3xTg Mouse Model of Alzheimer's Disease","title_match":true,"year":2023},{"alzhub_score":39,"alzhub_url":"https://alzhub.org/study/genes-and-genetics-in-hyperhomocysteinemia-and-the-1-carbon-31369712","doi":"10.1139/cjpp-2019-0236","journal":"Canadian journal of physiology and pharmacology","n_participants":null,"pmid":"31369712","source_url":"https://pubmed.ncbi.nlm.nih.gov/31369712/","study_design":null,"title":"Genes and genetics in hyperhomocysteinemia and the \"1-carbon metabolism\": implications for retinal structure and eye functions","title_match":false,"year":2020},{"alzhub_score":43,"alzhub_url":"https://alzhub.org/study/glucagon-like-peptide-1-receptor-agonists-a-new-pharmacological-40042613","doi":"10.1007/s00115-025-01813-x","journal":"Der Nervenarzt","n_participants":null,"pmid":"40042613","source_url":"https://pubmed.ncbi.nlm.nih.gov/40042613/","study_design":null,"title":"[Glucagon-like peptide-1 receptor agonists: a new pharmacological treatment option for psychiatric illnesses?]","title_match":false,"year":2025},{"alzhub_score":43,"alzhub_url":"https://alzhub.org/study/the-expanding-role-of-semaglutide-beyond-glycemic-control-40620322","doi":"10.1007/s40200-025-01663-z","journal":"Journal of diabetes and metabolic disorders","n_participants":null,"pmid":"40620322","source_url":"https://pubmed.ncbi.nlm.nih.gov/40620322/","study_design":null,"title":"The expanding role of semaglutide: beyond glycemic control","title_match":false,"year":2025},{"alzhub_score":79,"alzhub_url":"https://alzhub.org/study/effect-of-glucagon-like-peptide-1-receptor-agonists-glp-1-ra-on-41862354","doi":"10.1016/j.clinthera.2026.02.010","journal":"Clinical therapeutics","n_participants":null,"pmid":"41862354","source_url":"https://pubmed.ncbi.nlm.nih.gov/41862354/","study_design":"systematic review","title":"Effect of Glucagon-Like-Peptide-1 Receptor Agonists (GLP-1 RA) on Neuropsychiatric Outcomes: A Systematic Review and Meta-Analysis","title_match":false,"year":2026},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/glp-1-and-underlying-beneficial-actions-in-alzheimer-s-disease-34552561","doi":"10.3389/fendo.2021.721198","journal":"Frontiers in endocrinology","n_participants":null,"pmid":"34552561","source_url":"https://pubmed.ncbi.nlm.nih.gov/34552561/","study_design":null,"title":"GLP-1 and Underlying Beneficial Actions in Alzheimer's Disease, Hypertension, and NASH","title_match":false,"year":2021},{"alzhub_score":43,"alzhub_url":"https://alzhub.org/study/glucagon-like-peptide-1-receptor-agonists-exciting-avenues-beyond-40142784","doi":"10.3390/jcm14061978","journal":"Journal of clinical medicine","n_participants":null,"pmid":"40142784","source_url":"https://pubmed.ncbi.nlm.nih.gov/40142784/","study_design":null,"title":"Glucagon-like Peptide-1 Receptor Agonists: Exciting Avenues Beyond Weight Loss","title_match":false,"year":2025},{"alzhub_score":63,"alzhub_url":"https://alzhub.org/study/glucagon-like-peptide-1-receptor-agonists-and-mental-health-a-41025359","doi":"10.12701/jyms.2025.42.61","journal":"Journal of Yeungnam medical science","n_participants":null,"pmid":"41025359","source_url":"https://pubmed.ncbi.nlm.nih.gov/41025359/","study_design":"cohort study","title":"Glucagon-like peptide-1 receptor agonists and mental health: a narrative review of emerging benefits and risks","title_match":false,"year":2025},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/abc-transporter-c1-prevents-dimethyl-fumarate-from-targeting-37508364","doi":"10.3390/biology12070932","journal":"Biology","n_participants":null,"pmid":"37508364","source_url":"https://pubmed.ncbi.nlm.nih.gov/37508364/","study_design":null,"title":"ABC Transporter C1 Prevents Dimethyl Fumarate from Targeting Alzheimer's Disease","title_match":false,"year":2023},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/metformin-attenuates-tau-pathology-in-tau-seeded-ps19-mice-36422837","doi":"10.1007/s13311-022-01316-6","journal":"Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics","n_participants":null,"pmid":"36422837","source_url":"https://pubmed.ncbi.nlm.nih.gov/36422837/","study_design":null,"title":"Metformin Attenuates Tau Pathology in Tau-Seeded PS19 Mice","title_match":false,"year":2023},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/metformin-new-applications-for-an-old-drug-36474458","doi":"10.1515/jbcpp-2022-0252","journal":"Journal of basic and clinical physiology and pharmacology","n_participants":null,"pmid":"36474458","source_url":"https://pubmed.ncbi.nlm.nih.gov/36474458/","study_design":null,"title":"Metformin: new applications for an old drug","title_match":false,"year":2023},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/lithium-in-drinking-water-and-alzheimer-s-dementia-epidemiological-36073313","doi":"10.1111/bdi.13257","journal":"Bipolar disorders","n_participants":null,"pmid":"36073313","source_url":"https://pubmed.ncbi.nlm.nih.gov/36073313/","study_design":null,"title":"Lithium in drinking water and Alzheimer's dementia: Epidemiological Findings from National Data Base of Japan","title_match":true,"year":2022},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/treatment-of-insomnia-effect-of-trazodone-and-hypnotics-on-sleep-34994734","doi":"10.12740/pp/125650","journal":"Psychiatria polska","n_participants":null,"pmid":"34994734","source_url":"https://pubmed.ncbi.nlm.nih.gov/34994734/","study_design":null,"title":"Treatment of insomnia - effect of trazodone and hypnotics on sleep","title_match":false,"year":2021},{"alzhub_score":61,"alzhub_url":"https://alzhub.org/study/alcohol-consumption-and-sleep-quality-a-community-based-study-33183388","doi":"10.1017/s1368980020004553","journal":"Public health nutrition","n_participants":905,"pmid":"33183388","source_url":"https://pubmed.ncbi.nlm.nih.gov/33183388/","study_design":"cross-sectional","title":"Alcohol consumption and sleep quality: a community-based study","title_match":true,"year":2021},{"alzhub_score":57,"alzhub_url":"https://alzhub.org/study/obstructive-sleep-apnea-and-cognitive-decline-a-review-of-potential-34071739","doi":"10.3390/brainsci11060706","journal":"Brain sciences","n_participants":null,"pmid":"34071739","source_url":"https://pubmed.ncbi.nlm.nih.gov/34071739/","study_design":"cohort study","title":"Obstructive Sleep Apnea and Cognitive Decline: A Review of Potential Vulnerability and Protective Factors","title_match":false,"year":2021},{"alzhub_score":59,"alzhub_url":"https://alzhub.org/study/metabolically-healthy-obesity-and-risk-of-leukoaraiosis-a-population-29643322","doi":"10.1507/endocrj.ej18-0023","journal":"Endocrine journal","n_participants":171,"pmid":"29643322","source_url":"https://pubmed.ncbi.nlm.nih.gov/29643322/","study_design":"cross-sectional","title":"Metabolically healthy obesity and risk of leukoaraiosis; a population based cross-sectional study","title_match":false,"year":2018},{"alzhub_score":43,"alzhub_url":"https://alzhub.org/study/outdoor-nighttime-light-exposure-light-pollution-is-associated-with-38405987","doi":"10.1101/2024.02.14.24302831","journal":"Frontiers in neuroscience","n_participants":null,"pmid":"38405987","source_url":"https://pubmed.ncbi.nlm.nih.gov/38405987/","study_design":null,"title":"Outdoor Nighttime Light Exposure (Light Pollution) is Associated with Alzheimer's Disease","title_match":false,"year":2024},{"alzhub_score":39,"alzhub_url":"https://alzhub.org/study/linking-mitochondrial-dysfunction-metabolic-syndrome-and-stress-27345267","doi":"10.1016/j.bbadis.2016.06.015","journal":"Biochimica et biophysica acta. Molecular basis of disease","n_participants":null,"pmid":"27345267","source_url":"https://pubmed.ncbi.nlm.nih.gov/27345267/","study_design":null,"title":"Linking mitochondrial dysfunction, metabolic syndrome and stress signaling in Neurodegeneration","title_match":false,"year":2017},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/the-fructose-survival-hypothesis-for-obesity-37482773","doi":"10.1098/rstb.2022.0230","journal":"Philosophical transactions of the Royal Society of London. Series B, Biological sciences","n_participants":null,"pmid":"37482773","source_url":"https://pubmed.ncbi.nlm.nih.gov/37482773/","study_design":null,"title":"The fructose survival hypothesis for obesity","title_match":false,"year":2023},{"alzhub_score":59,"alzhub_url":"https://alzhub.org/study/phenotypic-heterogeneity-of-type-2-diabetes-and-risks-of-41913207","doi":"10.1186/s12933-026-03147-7","journal":"Cardiovascular diabetology","n_participants":6406,"pmid":"41913207","source_url":"https://pubmed.ncbi.nlm.nih.gov/41913207/","study_design":null,"title":"Phenotypic heterogeneity of type 2 diabetes and risks of complications with a tree-like representation","title_match":false,"year":2026},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/towards-a-consensus-on-alzheimer-s-disease-comorbidity-34640387","doi":"10.3390/jcm10194360","journal":"Journal of clinical medicine","n_participants":null,"pmid":"34640387","source_url":"https://pubmed.ncbi.nlm.nih.gov/34640387/","study_design":null,"title":"Towards a Consensus on Alzheimer's Disease Comorbidity?","title_match":false,"year":2021},{"alzhub_score":38,"alzhub_url":"https://alzhub.org/study/cardiovascular-risk-profile-in-women-and-dementia-25351109","doi":"10.3233/jad-141629","journal":"Journal of Alzheimer's disease : JAD","n_participants":null,"pmid":"25351109","source_url":"https://pubmed.ncbi.nlm.nih.gov/25351109/","study_design":null,"title":"Cardiovascular risk profile in women and dementia","title_match":false,"year":2014},{"alzhub_score":52,"alzhub_url":"https://alzhub.org/study/cognition-and-brain-health-among-older-adults-in-iceland-the-ages-35978066","doi":"10.1007/s11357-022-00642-z","journal":"GeroScience","n_participants":1707,"pmid":"35978066","source_url":"https://pubmed.ncbi.nlm.nih.gov/35978066/","study_design":null,"title":"Cognition and brain health among older adults in Iceland: the AGES-Reykjavik study","title_match":false,"year":2022},{"alzhub_score":57,"alzhub_url":"https://alzhub.org/study/cognitive-reserve-and-brain-maintenance-in-aging-and-dementia-an-33492168","doi":"10.1080/23279095.2021.1872079","journal":"Applied neuropsychology. Adult","n_participants":null,"pmid":"33492168","source_url":"https://pubmed.ncbi.nlm.nih.gov/33492168/","study_design":"cohort study","title":"Cognitive reserve and brain maintenance in aging and dementia: An integrative review","title_match":false,"year":2022},{"alzhub_score":71,"alzhub_url":"https://alzhub.org/study/modifiable-risk-factors-for-stroke-dementia-and-late-life-depression-40180437","doi":"10.1136/jnnp-2024-334925","journal":"Journal of neurology, neurosurgery, and psychiatry","n_participants":null,"pmid":"40180437","source_url":"https://pubmed.ncbi.nlm.nih.gov/40180437/","study_design":"meta-analysis","title":"Modifiable risk factors for stroke, dementia and late-life depression: a systematic review and DALY-weighted risk factors for a composite outcome","title_match":false,"year":2025},{"alzhub_score":43,"alzhub_url":"https://alzhub.org/study/inclusion-exclusion-criteria-in-late-life-depression-antidepressant-27546477","doi":"10.1002/gps.4560","journal":"International journal of geriatric psychiatry","n_participants":null,"pmid":"27546477","source_url":"https://pubmed.ncbi.nlm.nih.gov/27546477/","study_design":null,"title":"Inclusion/exclusion criteria in late life depression antidepressant efficacy trials","title_match":false,"year":2017},{"alzhub_score":39,"alzhub_url":"https://alzhub.org/study/association-between-exposure-to-air-pollution-and-hippocampal-volume-31220475","doi":"10.1016/j.neuro.2019.06.005","journal":"Neurotoxicology","n_participants":null,"pmid":"31220475","source_url":"https://pubmed.ncbi.nlm.nih.gov/31220475/","study_design":null,"title":"Association between exposure to air pollution and hippocampal volume in adults in the UK Biobank","title_match":false,"year":2019},{"alzhub_score":43,"alzhub_url":"https://alzhub.org/study/causal-association-between-particulate-matter-2-5-and-alzheimer-s-38873321","doi":"10.3389/fpubh.2024.1343915","journal":"Frontiers in public health","n_participants":null,"pmid":"38873321","source_url":"https://pubmed.ncbi.nlm.nih.gov/38873321/","study_design":null,"title":"Causal association between particulate matter 2.5 and Alzheimer's disease: a Mendelian randomization study","title_match":false,"year":2024},{"alzhub_score":79,"alzhub_url":"https://alzhub.org/study/potentially-modifiable-risk-factors-for-dementia-and-mild-cognitive-38346414","doi":"10.1159/000536643","journal":"Dementia and geriatric cognitive disorders","n_participants":45,"pmid":"38346414","source_url":"https://pubmed.ncbi.nlm.nih.gov/38346414/","study_design":"meta-analysis","title":"Potentially Modifiable Risk Factors for Dementia and Mild Cognitive Impairment: An Umbrella Review and Meta-Analysis","title_match":false,"year":2024},{"alzhub_score":55,"alzhub_url":"https://alzhub.org/study/healthy-dietary-patterns-in-relation-to-cognitive-performance-and-40055039","doi":"10.1016/j.tjpad.2025.100100","journal":"The journal of prevention of Alzheimer's disease","n_participants":27773,"pmid":"40055039","source_url":"https://pubmed.ncbi.nlm.nih.gov/40055039/","study_design":null,"title":"Healthy dietary patterns in relation to cognitive performance and Alzheimer's disease mortality","title_match":false,"year":2025},{"alzhub_score":45,"alzhub_url":"https://alzhub.org/study/diet-and-alzheimer-s-disease-17764625","doi":"10.1007/s11910-007-0057-8","journal":"Current neurology and neuroscience reports","n_participants":null,"pmid":"17764625","source_url":"https://pubmed.ncbi.nlm.nih.gov/17764625/","study_design":null,"title":"Diet and Alzheimer's disease","title_match":false,"year":2007},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/smoking-and-alcohol-consumption-following-a-new-dementia-diagnosis-31587074","doi":"10.1093/geronb/gbz127","journal":"The journals of gerontology. Series B, Psychological sciences and social sciences","n_participants":null,"pmid":"31587074","source_url":"https://pubmed.ncbi.nlm.nih.gov/31587074/","study_design":null,"title":"Smoking and Alcohol Consumption Following a New Dementia Diagnosis","title_match":true,"year":2021},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/mediterranean-diet-polyphenols-anthocyanins-and-their-implications-33390135","doi":"10.2174/1389557521999201230200813","journal":"Mini reviews in medicinal chemistry","n_participants":null,"pmid":"33390135","source_url":"https://pubmed.ncbi.nlm.nih.gov/33390135/","study_design":null,"title":"Mediterranean Diet Polyphenols: Anthocyanins and Their Implications for Health","title_match":false,"year":2021},{"alzhub_score":70,"alzhub_url":"https://alzhub.org/study/associations-between-dietary-patterns-and-dementia-related-36960849","doi":"10.1002/alz.13048","journal":"Alzheimer's & dementia : the journal of the Alzheimer's Association","n_participants":610,"pmid":"36960849","source_url":"https://pubmed.ncbi.nlm.nih.gov/36960849/","study_design":"cohort study","title":"Associations between dietary patterns and dementia-related neuroimaging markers","title_match":false,"year":2023},{"alzhub_score":38,"alzhub_url":"https://alzhub.org/study/is-it-always-alzheimer-s-let-s-talk-to-our-patients-about-26559414","doi":"10.1007/s40520-015-0480-7","journal":"Aging clinical and experimental research","n_participants":null,"pmid":"26559414","source_url":"https://pubmed.ncbi.nlm.nih.gov/26559414/","study_design":null,"title":"Is it always Alzheimer's? Let's talk to our patients about \"cardiocerebrovascular\" prevention","title_match":false,"year":2016},{"alzhub_score":38,"alzhub_url":"https://alzhub.org/study/nutrition-and-cognitive-impairment-27571865","doi":"10.20960/nh.346","journal":"Nutricion hospitalaria","n_participants":null,"pmid":"27571865","source_url":"https://pubmed.ncbi.nlm.nih.gov/27571865/","study_design":null,"title":"[Nutrition and cognitive impairment]","title_match":false,"year":2016},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/ethics-of-digital-therapeutics-dtx-36196692","doi":"10.26355/eurrev_202209_29741","journal":"European review for medical and pharmacological sciences","n_participants":null,"pmid":"36196692","source_url":"https://pubmed.ncbi.nlm.nih.gov/36196692/","study_design":null,"title":"Ethics of digital therapeutics (DTx)","title_match":false,"year":2022},{"alzhub_score":43,"alzhub_url":"https://alzhub.org/study/nutrition-exercise-and-cognitive-rehabilitation-for-dementia-38854809","doi":"10.14789/jmj.jmj23-0032-r","journal":"Juntendo Iji zasshi = Juntendo medical journal","n_participants":null,"pmid":"38854809","source_url":"https://pubmed.ncbi.nlm.nih.gov/38854809/","study_design":null,"title":"Nutrition, Exercise, and Cognitive Rehabilitation for Dementia Prevention","title_match":false,"year":2024},{"alzhub_score":48,"alzhub_url":"https://alzhub.org/study/dietary-components-and-nutritional-strategies-for-dementia-prevention-37303177","doi":"10.2174/1567205020666230609155932","journal":"Current Alzheimer research","n_participants":null,"pmid":"37303177","source_url":"https://pubmed.ncbi.nlm.nih.gov/37303177/","study_design":null,"title":"Dietary Components and Nutritional Strategies for Dementia Prevention in the Elderly","title_match":false,"year":2023},{"alzhub_score":39,"alzhub_url":"https://alzhub.org/study/preventive-role-of-l-carnitine-and-balanced-diet-in-alzheimer-s-32635400","doi":"10.3390/nu12071987","journal":"Nutrients","n_participants":null,"pmid":"32635400","source_url":"https://pubmed.ncbi.nlm.nih.gov/32635400/","study_design":null,"title":"Preventive Role of L-Carnitine and Balanced Diet in Alzheimer's Disease","title_match":false,"year":2020},{"alzhub_score":63,"alzhub_url":"https://alzhub.org/study/retinal-functional-and-structural-neural-indices-potential-biomarkers-37182886","doi":"10.3233/jad-230104","journal":"Journal of Alzheimer's disease : JAD","n_participants":5666,"pmid":"37182886","source_url":"https://pubmed.ncbi.nlm.nih.gov/37182886/","study_design":"cross-sectional","title":"Retinal Functional and Structural Neural Indices: Potential Biomarkers for the Monitoring of Cerebral Neurodegeneration: The Maastricht Study","title_match":false,"year":2023},{"alzhub_score":46,"alzhub_url":"https://alzhub.org/study/nutrition-and-immunology-in-mental-health-precision-medicine-and-31568824","doi":"10.1016/j.bbi.2019.09.022","journal":"Brain, behavior, and immunity","n_participants":15,"pmid":"31568824","source_url":"https://pubmed.ncbi.nlm.nih.gov/31568824/","study_design":null,"title":"Nutrition and immunology in mental health: Precision medicine and integrative approaches to address unmet clinical needs in psychiatric treatments","title_match":false,"year":2020},{"alzhub_score":16,"alzhub_url":"https://alzhub.org/study/extracellular-cirp-induces-neurotoxic-astrocytes-via-trem-1-in-c554220d","doi":"10.64898/2026.09.18.752724","journal":"bioRxiv","n_participants":null,"pmid":null,"source_url":"https://doi.org/10.64898/2026.09.18.752724","study_design":null,"title":"Extracellular CIRP induces neurotoxic astrocytes via TREM-1 in Alzheimer\u2019s disease","title_match":false,"year":2026},{"alzhub_score":16,"alzhub_url":"https://alzhub.org/study/living-arrangements-shape-the-determinants-of-life-sustaining-bc771d3f","doi":"10.21203/rs.3.rs-10441296/v1","journal":"Research Square","n_participants":3787,"pmid":null,"source_url":"https://doi.org/10.21203/rs.3.rs-10441296/v1","study_design":"longitudinal study","title":"Living arrangements shape the determinants of life-sustaining treatment preferences among Korean older adults","title_match":false,"year":2026},{"alzhub_score":16,"alzhub_url":"https://alzhub.org/study/rna-sequencing-of-butyrate-treated-human-lymphoblastoid-cell-lines-d5e3353a","doi":"10.64898/2026.10.21.760620","journal":"bioRxiv","n_participants":null,"pmid":null,"source_url":"https://doi.org/10.64898/2026.10.21.760620","study_design":null,"title":"RNA-sequencing of butyrate-treated human lymphoblastoid cell lines shows dysregulated genes of multiple disease-related pathways","title_match":false,"year":2026},{"alzhub_score":16,"alzhub_url":"https://alzhub.org/study/a-physicist-s-perspective-on-metabolic-rejuvenation-after-50-a8f0164f","doi":"10.20944/preprints202609.0698.v1","journal":"Preprints.org","n_participants":null,"pmid":null,"source_url":"https://doi.org/10.20944/preprints202609.0698.v1","study_design":null,"title":"A Physicist's Perspective on Metabolic Rejuvenation After 50","title_match":false,"year":2026},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/beyond-glycemic-control-glp-1rabased-therapies-and-emerging-targets-fe439787","doi":"10.20944/preprints202602.0277.v1","journal":"Journal of clinical medicine","n_participants":null,"pmid":null,"source_url":"https://doi.org/10.20944/preprints202602.0277.v1","study_design":null,"title":"Beyond Glycemic Control: GLP-1RA\u2013Based Therapies and Emerging Targets Beyond the Metabolic Axis","title_match":false,"year":2026},{"alzhub_score":16,"alzhub_url":"https://alzhub.org/study/hepatic-and-brain-spatial-gene-expression-changes-in-intragastric-0146b3bc","doi":"10.21203/rs.3.rs-10760512/v1","journal":"Research Square","n_participants":null,"pmid":null,"source_url":"https://doi.org/10.21203/rs.3.rs-10760512/v1","study_design":null,"title":"Hepatic and Brain Spatial Gene Expression Changes in Intragastric Alcohol Fed APP/PS1 Alzheimer's Disease Mouse Model","title_match":true,"year":2026},{"alzhub_score":48,"alzhub_url":"https://alzhub.org/study/linking-modifiable-risk-factors-to-vascular-and-neurodegenerative-0bacb0b1","doi":"10.64898/2026.02.28.26347178","journal":"GeroScience","n_participants":null,"pmid":null,"source_url":"https://doi.org/10.64898/2026.02.28.26347178","study_design":"cross-sectional","title":"Linking Modifiable Risk Factors to Vascular and Neurodegenerative Brain Changes","title_match":false,"year":2026},{"alzhub_score":48,"alzhub_url":"https://alzhub.org/study/identification-of-chemicals-targeting-dementia-genes-and-pathways-in-47bb1ac3","doi":"10.64898/2025.12.19.695572","journal":"Alzheimer's & dementia : the journal of the Alzheimer's Association","n_participants":null,"pmid":null,"source_url":"https://doi.org/10.64898/2025.12.19.695572","study_design":null,"title":"Identification of chemicals targeting dementia genes and pathways in the Comparative Toxicogenomics Database","title_match":false,"year":2025},{"alzhub_score":16,"alzhub_url":"https://alzhub.org/study/clinically-recognised-alcohol-use-disorder-and-risk-of-dementia-0d5a1594","doi":"10.64898/2026.09.23.26363779","journal":"medRxiv","n_participants":null,"pmid":null,"source_url":"https://doi.org/10.64898/2026.09.23.26363779","study_design":"prospective cohort","title":"Clinically Recognised Alcohol Use Disorder and Risk of Dementia Subtypes in 1.3 Million Women: A Prospective Cohort Study","title_match":true,"year":2026},{"alzhub_score":16,"alzhub_url":"https://alzhub.org/study/aging-and-alcohol-withdrawal-escalate-cns-hyperexcitability-across-066e4624","doi":"10.21203/rs.3.rs-10907903/v1","journal":"Research Square","n_participants":null,"pmid":null,"source_url":"https://doi.org/10.21203/rs.3.rs-10907903/v1","study_design":null,"title":"Aging and Alcohol Withdrawal Escalate CNS Hyperexcitability Across the Lifespan","title_match":true,"year":2026},{"alzhub_score":16,"alzhub_url":"https://alzhub.org/study/postmortem-alterations-of-metabotropic-glutamate-receptors-across-65d6a8d2","doi":"10.64898/2026.08.29.748003","journal":"bioRxiv","n_participants":null,"pmid":null,"source_url":"https://doi.org/10.64898/2026.08.29.748003","study_design":null,"title":"Postmortem Alterations of Metabotropic Glutamate Receptors across Neuropsychiatric Disorders: A Systematic Review","title_match":false,"year":2026},{"alzhub_score":16,"alzhub_url":"https://alzhub.org/study/investigating-the-causal-relationship-between-neuroticism-and-0d107df7","doi":"10.64898/2026.08.01.26359481","journal":"medRxiv","n_participants":1277,"pmid":null,"source_url":"https://doi.org/10.64898/2026.08.01.26359481","study_design":null,"title":"Investigating the Causal Relationship between Neuroticism and Alzheimer\u2019s Disease Using Mendelian Randomization and the Mediating Role of Modifiable Risk Factors","title_match":false,"year":2026},{"alzhub_score":16,"alzhub_url":"https://alzhub.org/study/associations-of-lifestyle-factors-and-genetic-risk-with-risk-and-rate-dc6dfca0","doi":"10.31234/osf.io/9tsj3_v1","journal":"PsyArXiv","n_participants":null,"pmid":null,"source_url":"https://doi.org/10.31234/osf.io/9tsj3_v1","study_design":null,"title":"Associations of lifestyle factors and genetic risk with risk and rate advancement periods of dementia","title_match":false,"year":2026},{"alzhub_score":76,"alzhub_url":"https://alzhub.org/study/technology-literacy-as-a-barrier-to-telehealth-during-covid-19-32429770","doi":"10.1089/tmj.2020.0155","journal":"Telemedicine Journal and e-Health","n_participants":5000,"pmid":"32429770","source_url":"https://pubmed.ncbi.nlm.nih.gov/32429770/","study_design":"randomized controlled trial","title":"Technology Literacy as a Barrier to Telehealth During COVID-19","title_match":false,"year":2020},{"alzhub_score":71,"alzhub_url":"https://alzhub.org/study/association-of-lithium-in-drinking-water-with-the-incidence-of-28832877","doi":"10.1001/jamapsychiatry.2017.2362","journal":"JAMA Psychiatry","n_participants":731,"pmid":"28832877","source_url":"https://pubmed.ncbi.nlm.nih.gov/28832877/","study_design":"case-control study","title":"Association of Lithium in Drinking Water With the Incidence of Dementia","title_match":true,"year":2017},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/deaths-preliminary-data-for-2002-14998175","doi":null,"journal":"PubMed","n_participants":null,"pmid":"14998175","source_url":"https://pubmed.ncbi.nlm.nih.gov/14998175/","study_design":null,"title":"Deaths: preliminary data for 2002","title_match":false,"year":2004},{"alzhub_score":45,"alzhub_url":"https://alzhub.org/study/the-cochrane-database-of-systematic-reviews-issue-4-2008-36b8f4be","doi":"10.1111/j.1756-5391.2008.00009.x","journal":"Journal of Evidence-Based Medicine","n_participants":8000,"pmid":null,"source_url":"https://doi.org/10.1111/j.1756-5391.2008.00009.x","study_design":null,"title":"The Cochrane Database of Systematic Reviews \u2013 Issue 4 2008","title_match":false,"year":2008},{"alzhub_score":59,"alzhub_url":"https://alzhub.org/study/the-canadian-study-of-health-and-aging-9056606","doi":"10.1161/01.str.28.3.526","journal":"Stroke","n_participants":129,"pmid":"9056606","source_url":"https://pubmed.ncbi.nlm.nih.gov/9056606/","study_design":"case-control study","title":"The Canadian Study of Health and Aging","title_match":false,"year":1997},{"alzhub_score":40,"alzhub_url":"https://alzhub.org/study/depressive-symptoms-and-cognitive-decline-in-nondemented-elderly-10232297","doi":"10.1001/archpsyc.56.5.425","journal":"PubMed","n_participants":null,"pmid":"10232297","source_url":"https://pubmed.ncbi.nlm.nih.gov/10232297/","study_design":null,"title":"Depressive symptoms and cognitive decline in nondemented elderly women: a prospective study","title_match":false,"year":1999},{"alzhub_score":40,"alzhub_url":"https://alzhub.org/study/epidemiology-of-early-onset-dementia-a-review-of-the-literature-23878613","doi":"10.2174/1745017901309010088","journal":"Clinical Practice and Epidemiology in Mental Health","n_participants":null,"pmid":"23878613","source_url":"https://pubmed.ncbi.nlm.nih.gov/23878613/","study_design":null,"title":"Epidemiology of early-onset dementia: a review of the literature","title_match":false,"year":2013},{"alzhub_score":43,"alzhub_url":"https://alzhub.org/study/alcohol-drinking-in-middle-age-and-subsequent-risk-of-mild-cognitive-15304383","doi":"10.1136/bmj.38181.418958.be","journal":"BMJ","n_participants":null,"pmid":"15304383","source_url":"https://pubmed.ncbi.nlm.nih.gov/15304383/","study_design":null,"title":"Alcohol drinking in middle age and subsequent risk of mild cognitive impairment and dementia in old age: a prospective population based study","title_match":true,"year":2004},{"alzhub_score":40,"alzhub_url":"https://alzhub.org/study/resveratrol-promotes-clearance-of-alzheimer-s-disease-amyloid-peptides-16162502","doi":"10.1074/jbc.m508246200","journal":"Journal of Biological Chemistry","n_participants":null,"pmid":"16162502","source_url":"https://pubmed.ncbi.nlm.nih.gov/16162502/","study_design":null,"title":"Resveratrol Promotes Clearance of Alzheimer's Disease Amyloid-\u03b2 Peptides","title_match":false,"year":2005},{"alzhub_score":43,"alzhub_url":"https://alzhub.org/study/gastrodin-and-gastrodigenin-improve-energy-metabolism-disorders-and-36985572","doi":"10.3390/molecules28062598","journal":"Molecules (Basel, Switzerland)","n_participants":null,"pmid":"36985572","source_url":"https://pubmed.ncbi.nlm.nih.gov/36985572/","study_design":null,"title":"Gastrodin and Gastrodigenin Improve Energy Metabolism Disorders and Mitochondrial Dysfunction to Antagonize Vascular Dementia","title_match":false,"year":2023},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/chronic-nicotine-treatment-reduces-beta-amyloidosis-in-the-brain-of-a-12065674","doi":"10.1046/j.1471-4159.2002.00874.x","journal":"Journal of neurochemistry","n_participants":null,"pmid":"12065674","source_url":"https://pubmed.ncbi.nlm.nih.gov/12065674/","study_design":null,"title":"Chronic nicotine treatment reduces beta-amyloidosis in the brain of a mouse model of Alzheimer's disease (APPsw)","title_match":false,"year":2002},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/chronic-exposure-to-aluminum-in-drinking-water-increases-inflammatory-14743440","doi":"10.1002/jnr.10877","journal":"Journal of neuroscience research","n_participants":null,"pmid":"14743440","source_url":"https://pubmed.ncbi.nlm.nih.gov/14743440/","study_design":null,"title":"Chronic exposure to aluminum in drinking water increases inflammatory parameters selectively in the brain","title_match":true,"year":2004},{"alzhub_score":41,"alzhub_url":"https://alzhub.org/study/beneficial-effects-of-low-alcohol-exposure-but-adverse-effects-of-29396480","doi":"10.1038/s41598-018-20424-y","journal":"Scientific reports","n_participants":null,"pmid":"29396480","source_url":"https://pubmed.ncbi.nlm.nih.gov/29396480/","study_design":null,"title":"Beneficial effects of low alcohol exposure, but adverse effects of high alcohol intake on glymphatic function","title_match":true,"year":2018},{"alzhub_score":40,"alzhub_url":"https://alzhub.org/study/is-there-chronic-brain-damage-in-retired-nfl-players-neuroradiology-25177413","doi":"10.1177/1941738114540270","journal":"Sports health","n_participants":null,"pmid":"25177413","source_url":"https://pubmed.ncbi.nlm.nih.gov/25177413/","study_design":null,"title":"Is There Chronic Brain Damage in Retired NFL Players? Neuroradiology, Neuropsychology, and Neurology Examinations of 45 Retired Players","title_match":false,"year":2014},{"alzhub_score":45,"alzhub_url":"https://alzhub.org/study/the-associations-between-a-capsaicin-rich-diet-and-blood-amyloid-27079706","doi":"10.3233/jad-151079","journal":"Journal of Alzheimer's disease : JAD","n_participants":338,"pmid":"27079706","source_url":"https://pubmed.ncbi.nlm.nih.gov/27079706/","study_design":null,"title":"The Associations between a Capsaicin-Rich Diet and Blood Amyloid-\u03b2 Levels and Cognitive Function","title_match":false,"year":2016},{"alzhub_score":62,"alzhub_url":"https://alzhub.org/study/association-between-modifiable-risk-factors-and-levels-of-blood-based-38204926","doi":"10.14283/jarlife.2024.1","journal":"JAR life","n_participants":779,"pmid":"38204926","source_url":"https://pubmed.ncbi.nlm.nih.gov/38204926/","study_design":null,"title":"Association between Modifiable Risk Factors and Levels of Blood-Based Biomarkers of Alzheimer's and Related Dementias in the Look AHEAD Cohort","title_match":false,"year":2024},{"alzhub_score":55,"alzhub_url":"https://alzhub.org/study/use-of-the-stroop-encephalapp-for-covert-hepatic-encephalopathy-33237215","doi":"10.1590/s0004-2803.202000000-73","journal":"Arquivos de gastroenterologia","n_participants":82,"pmid":"33237215","source_url":"https://pubmed.ncbi.nlm.nih.gov/33237215/","study_design":"cross-sectional","title":"USE OF THE STROOP ENCEPHALAPP FOR COVERT HEPATIC ENCEPHALOPATHY SCREENING IN CIRRHOTIC PATIENTS IN SOUTHERN BRAZIL","title_match":false,"year":2020},{"alzhub_score":45,"alzhub_url":"https://alzhub.org/study/smartwatch-based-interventions-for-people-with-dementia-user-centered-38848116","doi":"10.2196/50107","journal":"JMIR aging","n_participants":null,"pmid":"38848116","source_url":"https://pubmed.ncbi.nlm.nih.gov/38848116/","study_design":null,"title":"Smartwatch-Based Interventions for People With Dementia: User-Centered Design Approach","title_match":false,"year":2024},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/aluminium-as-a-risk-factor-in-alzheimer-s-disease-with-emphasis-on-11470314","doi":"10.1016/s0361-9230(01)00459-2","journal":"Brain research bulletin","n_participants":null,"pmid":"11470314","source_url":"https://pubmed.ncbi.nlm.nih.gov/11470314/","study_design":null,"title":"Aluminium as a risk factor in Alzheimer's disease, with emphasis on drinking water","title_match":true,"year":2001},{"alzhub_score":36,"alzhub_url":"https://alzhub.org/study/cholesterol-modulates-alpha-secretase-cleavage-of-amyloid-precursor-8626795","doi":"10.1074/jbc.271.8.4436","journal":"The Journal of biological chemistry","n_participants":null,"pmid":"8626795","source_url":"https://pubmed.ncbi.nlm.nih.gov/8626795/","study_design":null,"title":"Cholesterol modulates alpha-secretase cleavage of amyloid precursor protein","title_match":false,"year":1996},{"alzhub_score":40,"alzhub_url":"https://alzhub.org/study/chronic-exposure-of-alcohol-triggers-microglia-mediated-synaptic-35367455","doi":"10.1016/j.expneurol.2022.114061","journal":"Experimental neurology","n_participants":null,"pmid":"35367455","source_url":"https://pubmed.ncbi.nlm.nih.gov/35367455/","study_design":null,"title":"Chronic exposure of alcohol triggers microglia-mediated synaptic elimination inducing cognitive impairment","title_match":true,"year":2022},{"alzhub_score":43,"alzhub_url":"https://alzhub.org/study/chronic-ethanol-causes-persistent-increases-in-alzheimer-s-tau-35645744","doi":"10.3389/fnbeh.2022.886634","journal":"Frontiers in behavioral neuroscience","n_participants":null,"pmid":"35645744","source_url":"https://pubmed.ncbi.nlm.nih.gov/35645744/","study_design":null,"title":"Chronic Ethanol Causes Persistent Increases in Alzheimer's Tau Pathology in Female 3xTg-AD Mice: A Potential Role for Lysosomal Impairment","title_match":true,"year":2022},{"alzhub_score":52,"alzhub_url":"https://alzhub.org/study/caffeine-protects-alzheimer-s-mice-against-cognitive-impairment-and-16938404","doi":"10.1016/j.neuroscience.2006.07.021","journal":"Neuroscience","n_participants":null,"pmid":"16938404","source_url":"https://pubmed.ncbi.nlm.nih.gov/16938404/","study_design":"longitudinal study","title":"Caffeine protects Alzheimer's mice against cognitive impairment and reduces brain beta-amyloid production","title_match":false,"year":2006}]}
